3DS1A

Hiv-1 capsid c-terminal domain mutant (e187a) in complex with an inhibitor of particle assembly (cai)
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
81
structure length
81
Chain Sequence
TSILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNWMTATLLVQNANPDCKTILKALGPGATLEEMMTACQGVGGPGHKA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Residues in the HIV-1 Capsid Assembly Inhibitor Binding Site Are Essential for Maintaining the Assembly-competent Quaternary Structure of the Capsid Protein.
pubmed doi rcsb
molecule tags Viral protein
source organism Human immunodeficiency virus 1
molecule keywords HIV-1 CAPSID PROTEIN
total genus 29
structure length 81
sequence length 81
ec nomenclature ec 2.7.7.49: RNA-directed DNA polymerase.
pdb deposition date 2008-07-11
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.30 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A 3ds1A00
2JO0A 1EIAA 3DPHA 3DS0A 3P05A 3G29A 5HGLA 3DS3A 2EIAA 3DTJA 2JYLA 4U0FA 2L6EA 3H4EA 5HGMA 3DS1A 3G1GA 3DS2A 2BUOA 3H47A 4U0DA 4XRQA 4U0CA 1D1DA 2LF4A 4XFXA 3NTEA 1A43A 4PH0A 3LRYA 3VRLC 4XFYA 2KODA 2ONTA 3G28A 4M0IA 2JYGA 3DS5A 3G1IA 4QNBA 4XROA 3G26A 3MGEA 4IPYA 1BAJA 1E6JP 3DS4A 1A8OA 2M8PA 2XV6A 3G0VA 5HGNA 4U0AA 4COPA 2M8NA 3G21A 4U0EA 4COCA 5DCKA 5HGOA 4PH1A 5JPAA 1AUMA 4U0BA 2XXMA 4WYMA 1QRJA 4XFZA 1EOQA 2M8LA 2XT1A 5I4TG
chains in the Genus database with same CATH superfamily
2K0YA 2JYLA 3HYBA 4U0FA 3RG6C 1EMVA 3H47A 2QNWA 4CA3A 2MD9A 2QEXP 1YHQP 2FVEA 2PNGA 3G4SP 2AFDA 1VQOP 4IZ6A 1A8OA 2XV6A 1BXIA 2CWOA 1M74A 4COPA 1DV5A 4PH1A 2VLPA 2CNRA 3CE7A 2DNWA 1OR5A 2GZGA 3B5IA 5KP6B 1RO0A 2KORA 2MR8A 2CGQA 1D1DA 5KP7B 3NTEA 2CG5B 3I56P 3G6EP 2Z44A 4HKGA 1BAJA 3NY7B 1NQ4A 2KGCA 1AF8A 1QRJA 1VKUA 3CC7P 2M5RA 2XZ0D 4DG9A 1VQ5P 4U0CA 2OARA 2L22A 3DS5A 2PY8A 4XROA 2N50A 1YJ9P 1VQ8P 2XZ1C 5F2NA 2KOSA 3GZMA 4GR2A 1M6NA 2VLOA 1AUMA 2JGPA 1IUQA 1YI2P 3CD6P 2P9XA 4PH0A 1W2BO 1L0IA 1ACPA 1L0HA 2KOQA 4IPYA 1GXHA 2VSQA 2M8LA 1EOQA 1IMQA 2LPKA 2MR7A 3CXCO 1VQ4P 3CMAP 2K92A 2KGAA 2DGYA 1ZMBA 2GDXA 1HQBA 2EFJA 2GDWA 4QKOA 1AYIA 5HVCA 2JO0A 2FAEA 3P05A 1YITP 2K5XA 3DS2A 4XRQA 1E0HA 1HY8A 1K73Q 3G28A 2JYGA 2LTEA 2OTJP 1VQ6P 3CCVP 2N98A 3Q20A 4PWVB 1GXGA 2KG8A 5BS2A 3G21A 5DCKA 2N5HA 1QVGO 3GKLC 3GZLA 3DPHA 5EW5E 2GZEA 1Q86Q 1JJ2O 2K2QA 4PXHB 1A43A 2K94A 3EJDA 2MVUA 4XFYA 2GZFA 2GYKA 4QNBA 2KGEA 3CC4P 1UJZA 1VQNP 2LMLA 5F2OA 4H2XC 2GZIA 2LOLA 2MF4A 1M6EX 5HGLA 2FQ0A 2N6ZA 1M1KQ 3I55P 2EIAA 5HGMA 3CCUP 4U0DA 5BS1A 4BPGA 2FACA 4M0IA 2JAZA 2PEOA 2PEIA 1YJNP 3G26A 1GPJA 3U43A 4U0EA 2AVAA 2GDYA 4GR6A 2PENA 1T8KA 3DS0A 3CPWO 2KR5A 3DS3A 2FVAA 3H4EA 3LMOA 1VQLP 2LL8A 2KODA 2FHSC 1Q7YQ 2JBGA 1VQPP 1QVFO 3HZQA 2ERHA 1YIJP 2PEKA 3CCMP 2JU2A 2WPTA 1N8RQ 1KC8Q 2KWLA 2EHSA 2E1MA 1VQ9P 3CCJP 1YJWP 1Z6MA 1VQ7P 2ROQA 2Z46A 3MGEA 3CCLP 7CEIA 4F37A 3OW2O 5CZDB 4U0BA 1VQMP 2XT1A 3E2DA 1RO2A 3G29A 2N6YA 3DS1A 3G1GA 2FADA 5KP8B 2LF4A 2K0XA 3LRYA 2LKIA 1K30A 2FQ1A 3EJBA 3DS4A 2L0QA 2N5IA 2VLQA 4R0MA 2KG9A 3GJNA 2K93A 1RNIA 2BHVA 2BUOA 2X2BA 3CCSP 1Q82Q 2EG5A 1MZ8A 1VHNA 5HGNA 2KGDA 4U0AA 5HGOA 2KOPA 2FQ2A 5JPAA 1K8AQ 4XFZA 2AFEA 3CCEP 2OTLP 3DTJA 5HV8A 1UNKA 1F80D 1KD1Q 3G71P 1S72P 2MY5A 2KW2A 3CMEP 3CC2P 1CEIA 2FVFA 4WYMA 5I4TG 2KOOA 3CCRP 2LIWA 3H0DA 4XFXA 2GZJA 4MRTC 5EJDA 3VRLC 1Q81Q 2JB0A 3CCQP 2M8PA 2EHTA 3G0VA 4BPHA 2L4BA 1KLPA 2LIUA 1K9MQ 2XXMA 2QA4P 3EJEA 2PEJA 2JQ4A 2L6EA 1VQKP 2VLNA 1DNYA 2ONTA 4NEOA 1NJIQ 2NO8A 2Z45A 2M8NA 4COCA 3M1MA 4UHPB 2CQ8A 2KG6A 2JU1A 1EIAA 4H2YC 1KQSO 2L9FA 4BPFA 1IMPA 1ZNVA 3WBHA 2AF8A 4H2WC 3G1IA 3B4QA 1FR2A 2MVVA 1E6JP 1X3OA 5F2KA 3RG2A 2PEMA 2PEQA 1M90Q 2K0DX
chains in the Genus database with same CATH topology
3CCEP 3DS0A 3CXCO 2OTLP 3CPWO 3DS3A 3DTJA 2JYLA 3HYBA 4U0FA 3RG6C 1VQ4P 3H4EA 3CMAP 3H47A 2QEXP 1VQLP 1KD1Q 2DGYA 2KODA 1ZMBA 1YHQP 3G71P 3G4SP 1Q7YQ 1VQOP 1VQPP 1S72P 1QVFO 3HZQA 1A8OA 2XV6A 3CMEP 2CWOA 1M74A 4COPA 1YIJP 3CC2P 4PH1A 2PEKA 3CCMP 2EFJA 4WYMA 1N8RQ 1KC8Q 5I4TG 2JO0A 3P05A 3B5IA 3CCRP 1RO0A 1YITP 2E1MA 3DS2A 3H0DA 1VQ9P 3CCJP 4XRQA 1D1DA 4XFXA 3NTEA 1YJWP 3I56P 3VRLC 3G6EP 1Q81Q 2Z44A 1K73Q 3G28A 2JYGA 1VQ7P 2OTJP 2Z46A 3CCQP 3MGEA 3CCVP 1VQ6P 3CCLP 1BAJA 3Q20A 2M8PA 3G0VA 5BS2A 3G21A 3OW2O 5DCKA 1K9MQ 4U0BA 2XXMA 1QRJA 2QA4P 1VQMP 1QVGO 2XT1A 3CC7P 3E2DA 3DPHA 1RO2A 3G29A 2PEJA 2L6EA 1Q86Q 1VQKP 3DS1A 3G1GA 1JJ2O 1VQ5P 4U0CA 2LF4A 2OARA 1A43A 3LRYA 4XFYA 2ONTA 4QNBA 3DS5A 2PY8A 4XROA 1NJIQ 1K30A 1YJ9P 3CC4P 1VQ8P 1VQNP 5F2OA 5F2NA 2Z45A 3DS4A 2M8NA 4COCA 3M1MA 4GR2A 1M6NA 1AUMA 1RNIA 1M6EX 5HGLA 1EIAA 1IUQA 1M1KQ 3I55P 2EIAA 1YI2P 3CD6P 1KQSO 5HGMA 3CCUP 2BHVA 2BUOA 4U0DA 2P9XA 3WBHA 4PH0A 5BS1A 1W2BO 3CCSP 1Q82Q 4M0IA 2EG5A 3G1IA 2PEOA 2PEIA 1YJNP 3G26A 4IPYA 1E6JP 5HGNA 5F2KA 4U0AA 4U0EA 5HGOA 2PEMA 4GR6A 5JPAA 2PEQA 1M90Q 1K8AQ 4XFZA 1EOQA 2PENA 2M8LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JO0 A;  1EIA A;  3DPH A;  3DS0 A;  3P05 A;  3G29 A;  5HGL A;  3DS3 A;  2EIA A;  3DTJ A;  2JYL A;  4U0F A;  2L6E A;  3H4E A;  5HGM A;  3DS1 A;  3G1G A;  3DS2 A;  2BUO A;  3H47 A;  4U0D A;  4XRQ A;  4U0C A;  1D1D A;  2LF4 A;  4XFX A;  3NTE A;  1A43 A;  4PH0 A;  3LRY A;  3VRL C;  4XFY A;  2KOD A;  2ONT A;  3G28 A;  4M0I A;  2JYG A;  3DS5 A;  3G1I A;  4QNB A;  4XRO A;  3G26 A;  3MGE A;  4IPY A;  1BAJ A;  1E6J P;  3DS4 A;  1A8O A;  2M8P A;  2XV6 A;  3G0V A;  5HGN A;  4U0A A;  4COP A;  2M8N A;  3G21 A;  4U0E A;  4COC A;  5DCK A;  5HGO A;  4PH1 A;  5JPA A;  1AUM A;  4U0B A;  2XXM A;  4WYM A;  1QRJ A;  4XFZ A;  1EOQ A;  2M8L A;  2XT1 A;  5I4T G; 
#chains in the Genus database with same CATH topology
 2K0Y A;  2JYL A;  3HYB A;  4U0F A;  3RG6 C;  1EMV A;  3H47 A;  2QNW A;  4CA3 A;  2MD9 A;  2QEX P;  1YHQ P;  2FVE A;  2PNG A;  3G4S P;  2AFD A;  1VQO P;  4IZ6 A;  1A8O A;  2XV6 A;  1BXI A;  2CWO A;  1M74 A;  4COP A;  1DV5 A;  4PH1 A;  2VLP A;  2CNR A;  3CE7 A;  2DNW A;  1OR5 A;  2GZG A;  3B5I A;  5KP6 B;  1RO0 A;  2KOR A;  2MR8 A;  2CGQ A;  1D1D A;  5KP7 B;  3NTE A;  2CG5 B;  3I56 P;  3G6E P;  2Z44 A;  4HKG A;  1BAJ A;  3NY7 B;  1NQ4 A;  2KGC A;  1AF8 A;  1QRJ A;  1VKU A;  3CC7 P;  2M5R A;  2XZ0 D;  4DG9 A;  1VQ5 P;  4U0C A;  2OAR A;  2L22 A;  3DS5 A;  2PY8 A;  4XRO A;  2N50 A;  1YJ9 P;  1VQ8 P;  2XZ1 C;  5F2N A;  2KOS A;  3GZM A;  4GR2 A;  1M6N A;  2VLO A;  1AUM A;  2JGP A;  1IUQ A;  1YI2 P;  3CD6 P;  2P9X A;  4PH0 A;  1W2B O;  1L0I A;  1ACP A;  1L0H A;  2KOQ A;  4IPY A;  1GXH A;  2VSQ A;  2M8L A;  1EOQ A;  1IMQ A;  2LPK A;  2MR7 A;  3CXC O;  1VQ4 P;  3CMA P;  2K92 A;  2KGA A;  2DGY A;  1ZMB A;  2GDX A;  1HQB A;  2EFJ A;  2GDW A;  4QKO A;  1AYI A;  5HVC A;  2JO0 A;  2FAE A;  3P05 A;  1YIT P;  2K5X A;  3DS2 A;  4XRQ A;  1E0H A;  1HY8 A;  1K73 Q;  3G28 A;  2JYG A;  2LTE A;  2OTJ P;  1VQ6 P;  3CCV P;  2N98 A;  3Q20 A;  4PWV B;  1GXG A;  2KG8 A;  5BS2 A;  3G21 A;  5DCK A;  2N5H A;  1QVG O;  3GKL C;  3GZL A;  3DPH A;  5EW5 E;  2GZE A;  1Q86 Q;  1JJ2 O;  2K2Q A;  4PXH B;  1A43 A;  2K94 A;  3EJD A;  2MVU A;  4XFY A;  2GZF A;  2GYK A;  4QNB A;  2KGE A;  3CC4 P;  1UJZ A;  1VQN P;  2LML A;  5F2O A;  4H2X C;  2GZI A;  2LOL A;  2MF4 A;  1M6E X;  5HGL A;  2FQ0 A;  2N6Z A;  1M1K Q;  3I55 P;  2EIA A;  5HGM A;  3CCU P;  4U0D A;  5BS1 A;  4BPG A;  2FAC A;  4M0I A;  2JAZ A;  2PEO A;  2PEI A;  1YJN P;  3G26 A;  1GPJ A;  3U43 A;  4U0E A;  2AVA A;  2GDY A;  4GR6 A;  2PEN A;  1T8K A;  3DS0 A;  3CPW O;  2KR5 A;  3DS3 A;  2FVA A;  3H4E A;  3LMO A;  1VQL P;  2LL8 A;  2KOD A;  2FHS C;  1Q7Y Q;  2JBG A;  1VQP P;  1QVF O;  3HZQ A;  2ERH A;  1YIJ P;  2PEK A;  3CCM P;  2JU2 A;  2WPT A;  1N8R Q;  1KC8 Q;  2KWL A;  2EHS A;  2E1M A;  1VQ9 P;  3CCJ P;  1YJW P;  1Z6M A;  1VQ7 P;  2ROQ A;  2Z46 A;  3MGE A;  3CCL P;  7CEI A;  4F37 A;  3OW2 O;  5CZD B;  4U0B A;  1VQM P;  2XT1 A;  3E2D A;  1RO2 A;  3G29 A;  2N6Y A;  3DS1 A;  3G1G A;  2FAD A;  5KP8 B;  2LF4 A;  2K0X A;  3LRY A;  2LKI A;  1K30 A;  2FQ1 A;  3EJB A;  3DS4 A;  2L0Q A;  2N5I A;  2VLQ A;  4R0M A;  2KG9 A;  3GJN A;  2K93 A;  1RNI A;  2BHV A;  2BUO A;  2X2B A;  3CCS P;  1Q82 Q;  2EG5 A;  1MZ8 A;  1VHN A;  5HGN A;  2KGD A;  4U0A A;  5HGO A;  2KOP A;  2FQ2 A;  5JPA A;  1K8A Q;  4XFZ A;  2AFE A;  3CCE P;  2OTL P;  3DTJ A;  5HV8 A;  1UNK A;  1F80 D;  1KD1 Q;  3G71 P;  1S72 P;  2MY5 A;  2KW2 A;  3CME P;  3CC2 P;  1CEI A;  2FVF A;  4WYM A;  5I4T G;  2KOO A;  3CCR P;  2LIW A;  3H0D A;  4XFX A;  2GZJ A;  4MRT C;  5EJD A;  3VRL C;  1Q81 Q;  2JB0 A;  3CCQ P;  2M8P A;  2EHT A;  3G0V A;  4BPH A;  2L4B A;  1KLP A;  2LIU A;  1K9M Q;  2XXM A;  2QA4 P;  3EJE A;  2PEJ A;  2JQ4 A;  2L6E A;  1VQK P;  2VLN A;  1DNY A;  2ONT A;  4NEO A;  1NJI Q;  2NO8 A;  2Z45 A;  2M8N A;  4COC A;  3M1M A;  4UHP B;  2CQ8 A;  2KG6 A;  2JU1 A;  1EIA A;  4H2Y C;  1KQS O;  2L9F A;  4BPF A;  1IMP A;  1ZNV A;  3WBH A;  2AF8 A;  4H2W C;  3G1I A;  3B4Q A;  1FR2 A;  2MVV A;  1E6J P;  1X3O A;  5F2K A;  3RG2 A;  2PEM A;  2PEQ A;  1M90 Q;  2K0D X; 
#chains in the Genus database with same CATH homology
 3CCE P;  3DS0 A;  3CXC O;  2OTL P;  3CPW O;  3DS3 A;  3DTJ A;  2JYL A;  3HYB A;  4U0F A;  3RG6 C;  1VQ4 P;  3H4E A;  3CMA P;  3H47 A;  2QEX P;  1VQL P;  1KD1 Q;  2DGY A;  2KOD A;  1ZMB A;  1YHQ P;  3G71 P;  3G4S P;  1Q7Y Q;  1VQO P;  1VQP P;  1S72 P;  1QVF O;  3HZQ A;  1A8O A;  2XV6 A;  3CME P;  2CWO A;  1M74 A;  4COP A;  1YIJ P;  3CC2 P;  4PH1 A;  2PEK A;  3CCM P;  2EFJ A;  4WYM A;  1N8R Q;  1KC8 Q;  5I4T G;  2JO0 A;  3P05 A;  3B5I A;  3CCR P;  1RO0 A;  1YIT P;  2E1M A;  3DS2 A;  3H0D A;  1VQ9 P;  3CCJ P;  4XRQ A;  1D1D A;  4XFX A;  3NTE A;  1YJW P;  3I56 P;  3VRL C;  3G6E P;  1Q81 Q;  2Z44 A;  1K73 Q;  3G28 A;  2JYG A;  1VQ7 P;  2OTJ P;  2Z46 A;  3CCQ P;  3MGE A;  3CCV P;  1VQ6 P;  3CCL P;  1BAJ A;  3Q20 A;  2M8P A;  3G0V A;  5BS2 A;  3G21 A;  3OW2 O;  5DCK A;  1K9M Q;  4U0B A;  2XXM A;  1QRJ A;  2QA4 P;  1VQM P;  1QVG O;  2XT1 A;  3CC7 P;  3E2D A;  3DPH A;  1RO2 A;  3G29 A;  2PEJ A;  2L6E A;  1Q86 Q;  1VQK P;  3DS1 A;  3G1G A;  1JJ2 O;  1VQ5 P;  4U0C A;  2LF4 A;  2OAR A;  1A43 A;  3LRY A;  4XFY A;  2ONT A;  4QNB A;  3DS5 A;  2PY8 A;  4XRO A;  1NJI Q;  1K30 A;  1YJ9 P;  3CC4 P;  1VQ8 P;  1VQN P;  5F2O A;  5F2N A;  2Z45 A;  3DS4 A;  2M8N A;  4COC A;  3M1M A;  4GR2 A;  1M6N A;  1AUM A;  1RNI A;  1M6E X;  5HGL A;  1EIA A;  1IUQ A;  1M1K Q;  3I55 P;  2EIA A;  1YI2 P;  3CD6 P;  1KQS O;  5HGM A;  3CCU P;  2BHV A;  2BUO A;  4U0D A;  2P9X A;  3WBH A;  4PH0 A;  5BS1 A;  1W2B O;  3CCS P;  1Q82 Q;  4M0I A;  2EG5 A;  3G1I A;  2PEO A;  2PEI A;  1YJN P;  3G26 A;  4IPY A;  1E6J P;  5HGN A;  5F2K A;  4U0A A;  4U0E A;  5HGO A;  2PEM A;  4GR6 A;  5JPA A;  2PEQ A;  1M90 Q;  1K8A Q;  4XFZ A;  1EOQ A;  2PEN A;  2M8L A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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