3GJNA

Following evolutionary paths to high affinity and selectivity protein-protein interactions using colicin7 and immunity proteins
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
82
structure length
82
Chain Sequence
KHSISDYTEAEFLQLVTTICDAEATSEEELDKLITHFEEMTEHPSGSDLIYWPKEGDDDSPSGIVNTVKQWRAANGKSGFKQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Following evolutionary paths to protein-protein interactions with high affinity and selectivity
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords Colicin-E9 immunity protein
total genus 27
structure length 82
sequence length 82
chains with identical sequence D
ec nomenclature
pdb deposition date 2009-03-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01320 Colicin_Pyocin Colicin immunity protein / pyocin immunity protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.20 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A Colicin E immunity protein 3gjnA00
2GZJA 3U43A 1IMQA 1GXGA 7CEIA 2GYKA 1AYIA 1BXIA 1CEIA 1MZ8A 2JBGA 3GKLC 5EW5E 1E0HA 1GXHA 2VLNA 2JB0A 4QKOA 1UNKA 2K0DX 4UHPB 1FR2A 2K5XA 2VLQA 2VLOA 1EMVA 1IMPA 2GZIA 2GZGA 2ERHA 2WPTA 2JAZA 4F37A 1UJZA 1ZNVA 2VLPA 3GJNA 2NO8A 2GZEA 2GZFA
chains in the Genus database with same CATH superfamily
2LL8A 2KW2A 1YITP 2KOPA 2FACA 2JB0A 2PEQA 2L0QA 1K73Q 2FVFA 3NTEA 3LRYA 4U0DA 1A43A 3CCQP 1S72P 3CCMP 4MRTC 1ZNVA 2QEXP 5BS1A 1M1KQ 1VQ4P 3B5IA 3CCUP 4R0MA 3G28A 2JBGA 3CXCO 3G1IA 1VQ8P 5F2NA 4XRQA 2PNGA 2PEKA 3HYBA 3CCJP 2GDYA 1YJ9P 2MD9A 5KP7B 3DS4A 1VHNA 2WPTA 3EJEA 2FADA 3CMAP 4HKGA 4DG9A 2PEOA 1RO2A 1RNIA 2PY8A 2KGEA 2CNRA 1KQSO 3CD6P 1GPJA 1QRJA 3CC2P 2KODA 1Q82Q 2MR7A 2BHVA 2DNWA 1HQBA 2N50A 3U43A 1VQNP 1ACPA 4U0EA 4U0BA 1L0IA 4XFZA 2K2QA 2M8LA 2KG8A 3E2DA 4U0CA 2KR5A 4XFXA 2VLPA 2XZ1C 4PH1A 1GXHA 5HGMA 2FQ2A 1Q86Q 2N6YA 1D1DA 1CEIA 1MZ8A 3EJBA 2N98A 1X3OA 4UHPB 1YHQP 4BPHA 2VLQA 2L22A 2QA4P 2NO8A 2Z44A 1VQ5P 1AF8A 2MY5A 4COCA 2Z45A 3VRLC 2EHTA 4PH0A 2K0XA 4QKOA 2K0DX 2N5HA 3CCRP 4H2XC 1KD1Q 3RG6C 3H47A 3DS2A 3CCEP 5KP6B 3G21A 3DPHA 3GZMA 2MF4A 3CPWO 1M74A 3DS3A 1E0HA 2BUOA 5KP8B 1HY8A 1EOQA 1UNKA 1Z6MA 2LOLA 2ONTA 1F80D 4H2YC 1IMPA 2KORA 2OTLP 7CEIA 2GDWA 1RO0A 1AYIA 3CC4P 3G1GA 1NJIQ 2VLNA 3DS0A 2M5RA 4CA3A 2JU1A 5HV8A 1A8OA 4XROA 3WBHA 3G26A 2AF8A 4F37A 2XT1A 3CCVP 3Q20A 1AUMA 4COPA 2GYKA 3GKLC 2XV6A 4U0FA 1KC8Q 2ROQA 5BS2A 1OR5A 2KWLA 3P05A 3RG2A 2LPKA 4GR2A 1M90Q 2DGYA 5F2OA 4BPFA 2JYGA 1VQMP 2FAEA 2X2BA 2M8PA 3GJNA 2JYLA 1Q7YQ 4PWVB 1GXGA 3OW2O 2KG6A 2LIUA 1BXIA 1VQ6P 2JGPA 2KGDA 1K9MQ 3LMOA 2JO0A 2L4BA 2E1MA 2FVEA 1EIAA 1QVFO 2XXMA 2MR8A 1VQLP 3G0VA 5DCKA 1ZMBA 5I4TG 2EG5A 1M6EX 5F2KA 2CWOA 1KLPA 1W2BO 1VQ9P 1L0HA 2CG5B 3I56P 1FR2A 5JPAA 4IZ6A 2PENA 2GZIA 2ERHA 2VSQA 4GR6A 2LKIA 4U0AA 2CQ8A 2KOQA 1VKUA 2OARA 5CZDB 1BAJA 3CC7P 2PEIA 2GDXA 1YJWP 2JQ4A 2KG9A 1K30A 3NY7B 5HGNA 2K94A 1K8AQ 2KOSA 3DS5A 2FVAA 2K93A 3GZLA 2GZEA 3G6EP 2L6EA 2EHSA 3H0DA 3HZQA 3H4EA 3CCSP 1T8KA 2AFEA 4H2WC 4XFYA 2K0YA 2L9FA 1NQ4A 3G71P 2AFDA 5EJDA 1EMVA 2K92A 2GZGA 2KGCA 2LF4A 1DNYA 1UJZA 2EFJA 4NEOA 2GZFA 3MGEA 2FHSC 2MVUA 1IMQA 2MVVA 1IUQA 4WYMA 3DS1A 3B4QA 2K5XA 2LMLA 5HGLA 2P9XA 2N5IA 2Z46A 2M8NA 3CE7A 1N8RQ 3I55P 1E6JP 2PEJA 1QVGO 1YJNP 4IPYA 1JJ2O 1Q81Q 1VQKP 5HVCA 3CMEP 3DTJA 2N6ZA 1DV5A 3M1MA 2FQ0A 2PEMA 2AVAA 4QNBA 2KGAA 1YIJP 2JAZA 3G29A 3G4SP 2LIWA 1VQPP 2GZJA 2JU2A 1VQOP 4BPGA 2QNWA 2FQ1A 3CCLP 5EW5E 4PXHB 1M6NA 3EJDA 2XZ0D 2LTEA 2EIAA 2KOOA 5HGOA 2OTJP 2VLOA 1VQ7P 2CGQA 1YI2P 4M0IA
chains in the Genus database with same CATH topology
2GZJA 3U43A 1IMQA 1GXGA 7CEIA 2GYKA 1AYIA 1BXIA 1CEIA 1MZ8A 2JBGA 3GKLC 5EW5E 1E0HA 1GXHA 2VLNA 2JB0A 4QKOA 1UNKA 2K0DX 4UHPB 1FR2A 2K5XA 2VLQA 2VLOA 1EMVA 1IMPA 2GZIA 2GZGA 2ERHA 2WPTA 2JAZA 4F37A 1UJZA 1ZNVA 2VLPA 3GJNA 2NO8A 2GZEA 2GZFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GZJ A;  3U43 A;  1IMQ A;  1GXG A;  7CEI A;  2GYK A;  1AYI A;  1BXI A;  1CEI A;  1MZ8 A;  2JBG A;  3GKL C;  5EW5 E;  1E0H A;  1GXH A;  2VLN A;  2JB0 A;  4QKO A;  1UNK A;  2K0D X;  4UHP B;  1FR2 A;  2K5X A;  2VLQ A;  2VLO A;  1EMV A;  1IMP A;  2GZI A;  2GZG A;  2ERH A;  2WPT A;  2JAZ A;  4F37 A;  1UJZ A;  1ZNV A;  2VLP A;  3GJN A;  2NO8 A;  2GZE A;  2GZF A; 
#chains in the Genus database with same CATH topology
 2LL8 A;  2KW2 A;  1YIT P;  2KOP A;  2FAC A;  2JB0 A;  2PEQ A;  2L0Q A;  1K73 Q;  2FVF A;  3NTE A;  3LRY A;  4U0D A;  1A43 A;  3CCQ P;  1S72 P;  3CCM P;  4MRT C;  1ZNV A;  2QEX P;  5BS1 A;  1M1K Q;  1VQ4 P;  3B5I A;  3CCU P;  4R0M A;  3G28 A;  2JBG A;  3CXC O;  3G1I A;  1VQ8 P;  5F2N A;  4XRQ A;  2PNG A;  2PEK A;  3HYB A;  3CCJ P;  2GDY A;  1YJ9 P;  2MD9 A;  5KP7 B;  3DS4 A;  1VHN A;  2WPT A;  3EJE A;  2FAD A;  3CMA P;  4HKG A;  4DG9 A;  2PEO A;  1RO2 A;  1RNI A;  2PY8 A;  2KGE A;  2CNR A;  1KQS O;  3CD6 P;  1GPJ A;  1QRJ A;  3CC2 P;  2KOD A;  1Q82 Q;  2MR7 A;  2BHV A;  2DNW A;  1HQB A;  2N50 A;  3U43 A;  1VQN P;  1ACP A;  4U0E A;  4U0B A;  1L0I A;  4XFZ A;  2K2Q A;  2M8L A;  2KG8 A;  3E2D A;  4U0C A;  2KR5 A;  4XFX A;  2VLP A;  2XZ1 C;  4PH1 A;  1GXH A;  5HGM A;  2FQ2 A;  1Q86 Q;  2N6Y A;  1D1D A;  1CEI A;  1MZ8 A;  3EJB A;  2N98 A;  1X3O A;  4UHP B;  1YHQ P;  4BPH A;  2VLQ A;  2L22 A;  2QA4 P;  2NO8 A;  2Z44 A;  1VQ5 P;  1AF8 A;  2MY5 A;  4COC A;  2Z45 A;  3VRL C;  2EHT A;  4PH0 A;  2K0X A;  4QKO A;  2K0D X;  2N5H A;  3CCR P;  4H2X C;  1KD1 Q;  3RG6 C;  3H47 A;  3DS2 A;  3CCE P;  5KP6 B;  3G21 A;  3DPH A;  3GZM A;  2MF4 A;  3CPW O;  1M74 A;  3DS3 A;  1E0H A;  2BUO A;  5KP8 B;  1HY8 A;  1EOQ A;  1UNK A;  1Z6M A;  2LOL A;  2ONT A;  1F80 D;  4H2Y C;  1IMP A;  2KOR A;  2OTL P;  7CEI A;  2GDW A;  1RO0 A;  1AYI A;  3CC4 P;  3G1G A;  1NJI Q;  2VLN A;  3DS0 A;  2M5R A;  4CA3 A;  2JU1 A;  5HV8 A;  1A8O A;  4XRO A;  3WBH A;  3G26 A;  2AF8 A;  4F37 A;  2XT1 A;  3CCV P;  3Q20 A;  1AUM A;  4COP A;  2GYK A;  3GKL C;  2XV6 A;  4U0F A;  1KC8 Q;  2ROQ A;  5BS2 A;  1OR5 A;  2KWL A;  3P05 A;  3RG2 A;  2LPK A;  4GR2 A;  1M90 Q;  2DGY A;  5F2O A;  4BPF A;  2JYG A;  1VQM P;  2FAE A;  2X2B A;  2M8P A;  3GJN A;  2JYL A;  1Q7Y Q;  4PWV B;  1GXG A;  3OW2 O;  2KG6 A;  2LIU A;  1BXI A;  1VQ6 P;  2JGP A;  2KGD A;  1K9M Q;  3LMO A;  2JO0 A;  2L4B A;  2E1M A;  2FVE A;  1EIA A;  1QVF O;  2XXM A;  2MR8 A;  1VQL P;  3G0V A;  5DCK A;  1ZMB A;  5I4T G;  2EG5 A;  1M6E X;  5F2K A;  2CWO A;  1KLP A;  1W2B O;  1VQ9 P;  1L0H A;  2CG5 B;  3I56 P;  1FR2 A;  5JPA A;  4IZ6 A;  2PEN A;  2GZI A;  2ERH A;  2VSQ A;  4GR6 A;  2LKI A;  4U0A A;  2CQ8 A;  2KOQ A;  1VKU A;  2OAR A;  5CZD B;  1BAJ A;  3CC7 P;  2PEI A;  2GDX A;  1YJW P;  2JQ4 A;  2KG9 A;  1K30 A;  3NY7 B;  5HGN A;  2K94 A;  1K8A Q;  2KOS A;  3DS5 A;  2FVA A;  2K93 A;  3GZL A;  2GZE A;  3G6E P;  2L6E A;  2EHS A;  3H0D A;  3HZQ A;  3H4E A;  3CCS P;  1T8K A;  2AFE A;  4H2W C;  4XFY A;  2K0Y A;  2L9F A;  1NQ4 A;  3G71 P;  2AFD A;  5EJD A;  1EMV A;  2K92 A;  2GZG A;  2KGC A;  2LF4 A;  1DNY A;  1UJZ A;  2EFJ A;  4NEO A;  2GZF A;  3MGE A;  2FHS C;  2MVU A;  1IMQ A;  2MVV A;  1IUQ A;  4WYM A;  3DS1 A;  3B4Q A;  2K5X A;  2LML A;  5HGL A;  2P9X A;  2N5I A;  2Z46 A;  2M8N A;  3CE7 A;  1N8R Q;  3I55 P;  1E6J P;  2PEJ A;  1QVG O;  1YJN P;  4IPY A;  1JJ2 O;  1Q81 Q;  1VQK P;  5HVC A;  3CME P;  3DTJ A;  2N6Z A;  1DV5 A;  3M1M A;  2FQ0 A;  2PEM A;  2AVA A;  4QNB A;  2KGA A;  1YIJ P;  2JAZ A;  3G29 A;  3G4S P;  2LIW A;  1VQP P;  2GZJ A;  2JU2 A;  1VQO P;  4BPG A;  2QNW A;  2FQ1 A;  3CCL P;  5EW5 E;  4PXH B;  1M6N A;  3EJD A;  2XZ0 D;  2LTE A;  2EIA A;  2KOO A;  5HGO A;  2OTJ P;  2VLO A;  1VQ7 P;  2CGQ A;  1YI2 P;  4M0I A; 
#chains in the Genus database with same CATH homology
 2GZJ A;  3U43 A;  1IMQ A;  1GXG A;  7CEI A;  2GYK A;  1AYI A;  1BXI A;  1CEI A;  1MZ8 A;  2JBG A;  3GKL C;  5EW5 E;  1E0H A;  1GXH A;  2VLN A;  2JB0 A;  4QKO A;  1UNK A;  2K0D X;  4UHP B;  1FR2 A;  2K5X A;  2VLQ A;  2VLO A;  1EMV A;  1IMP A;  2GZI A;  2GZG A;  2ERH A;  2WPT A;  2JAZ A;  4F37 A;  1UJZ A;  1ZNV A;  2VLP A;  3GJN A;  2NO8 A;  2GZE A;  2GZF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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