3GKLC

Following evolutionary paths to high affinity and selectivity protein-protein interactions using colicin7 and immunity proteins
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
82
structure length
82
Chain Sequence
KHSISDYTEAEFLQLVATICDADATSEEELDKLITHFGEMTEHPSGSDLIYYPEEGDDDSPSGIVNTVKQWRAANGKSGFKQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Following evolutionary paths to high affinity and selectivity protein-protein interactions
rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords Colicin-E9 immunity protein
total genus 24
structure length 82
sequence length 82
chains with identical sequence D
ec nomenclature
pdb deposition date 2009-03-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF01320 Colicin_Pyocin Colicin immunity protein / pyocin immunity protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.20 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A Colicin E immunity protein 3gklC00
2VLPA 1GXHA 1EMVA 3GKLC 4F37A 4QKOA 2ERHA 1IMPA 2JAZA 2JBGA 1AYIA 5EW5E 3U43A 4UHPB 3GJNA 1E0HA 2VLQA 2GZJA 2GZGA 2JB0A 2VLOA 1UNKA 2NO8A 1MZ8A 2K0DX 1CEIA 1ZNVA 2GZEA 2WPTA 1FR2A 2GZIA 1BXIA 2GZFA 1GXGA 2GYKA 1UJZA 7CEIA 1IMQA 2K5XA 2VLNA
chains in the Genus database with same CATH superfamily
1VQ5P 1VKUA 2CG5B 5KP6B 1VQ7P 4H2XC 2ROQA 5F2KA 1E0HA 1YJ9P 3CC2P 1M1KQ 1UNKA 2K0DX 1NJIQ 2OTLP 1A43A 1VQPP 2GDYA 2GZFA 2EG5A 2K5XA 1ZMBA 1VQMP 3GKLC 2EIAA 3GZLA 2BUOA 4COPA 1VQLP 2MF4A 2FVFA 2KG9A 2FQ0A 2OARA 3I56P 2EFJA 1BXIA 2OTJP 2XZ0D 1EMVA 2E1MA 2FHSC 1YITP 2GDXA 4UHPB 5I4TG 1HQBA 5JPAA 5HGNA 2PEOA 2CGQA 3G21A 3MGEA 3DS1A 3CCJP 1GPJA 3CCSP 1NQ4A 2VLPA 4U0AA 2VSQA 2XT1A 4XRQA 4COCA 1K8AQ 1T8KA 2EHTA 2GZGA 5HV8A 4WYMA 1CEIA 1Q82Q 1VQ9P 2KWLA 2KG8A 2GDWA 4R0MA 2KGCA 1QVFO 2L4BA 3GJNA 3EJBA 2KOOA 2KODA 3G1IA 4QNBA 2ONTA 1X3OA 4XFXA 2PNGA 2KGDA 1W2BO 3RG6C 2M8NA 2LTEA 1GXHA 4IZ6A 1VQ4P 4DG9A 2M8LA 4HKGA 2KOQA 1KQSO 3Q20A 1Q7YQ 1Z6MA 2GZEA 2KOPA 2LL8A 1YJWP 3LMOA 3VRLC 3CCEP 3RG2A 2PEMA 3M1MA 4QKOA 2PEIA 2FADA 2FACA 2JBGA 2LF4A 3U43A 2K0XA 2N6ZA 3H0DA 3NTEA 4PWVB 5HVCA 2MR8A 1MZ8A 3G28A 2K92A 2K93A 2K94A 3DS0A 4PH1A 1FR2A 3LRYA 2QNWA 1Q86Q 2DGYA 2LKIA 2CNRA 2AFEA 1IMQA 2VLNA 3HZQA 2N5HA 4F37A 2KOSA 3GZMA 1KLPA 1EIAA 4GR2A 4U0BA 1K9MQ 4MRTC 2K0YA 2VLQA 4U0DA 2N98A 2PEKA 5EJDA 3EJDA 4H2YC 1AF8A 3DS5A 1K30A 3DS2A 2BHVA 1N8RQ 3G1GA 1HY8A 4BPHA 4GR6A 5BS2A 2M8PA 2LMLA 1S72P 2FVAA 2AF8A 2Z44A 3CXCO 3CPWO 1VQKP 2NO8A 3DPHA 5KP7B 2KG6A 2CQ8A 4CA3A 3NY7B 1D1DA 2WPTA 4NEOA 1DV5A 2KGAA 2MVUA 4BPGA 1M90Q 2FVEA 3CCRP 1M6EX 5F2NA 3G71P 4H2WC 2PEQA 3CC7P 1BAJA 1Q81Q 2QEXP 2LOLA 2JYGA 2L0QA 3DTJA 2N6YA 2QA4P 5HGMA 3G4SP 1VQOP 1EOQA 4IPYA 2ERHA 2JAZA 1M6NA 3WBHA 1ACPA 3CMAP 2GZJA 1VHNA 1JJ2O 1VQ6P 3CCLP 2XXMA 2LPKA 1QVGO 2PEJA 2JU2A 2EHSA 2N5IA 4U0CA 3P05A 2DNWA 5BS1A 1M74A 1YJNP 2KR5A 1KD1Q 2M5RA 4U0FA 1YIJP 2JB0A 4PXHB 3E2DA 1AUMA 2AVAA 2PENA 2Z45A 1VQNP 2KORA 2MR7A 1L0IA 3CE7A 1AYIA 2KGEA 3B5IA 3OW2O 2VLOA 2MVVA 2LIWA 2JGPA 2X2BA 2XZ1C 4BPFA 3CMEP 3CC4P 3EJEA 1RNIA 4M0IA 7CEIA 2LIUA 3DS3A 5F2OA 2K2QA 2CWOA 4XFZA 3G6EP 1F80D 3CCUP 3I55P 1RO0A 1A8OA 1ZNVA 1IUQA 2GZIA 1RO2A 3H47A 4PH0A 3G0VA 2JQ4A 4XROA 1YI2P 3G29A 2JYLA 2JU1A 1L0HA 1QRJA 2PY8A 2MD9A 5KP8B 2FQ1A 5EW5E 3B4QA 5CZDB 2L6EA 2JO0A 3CCQP 2MY5A 1VQ8P 2L22A 3HYBA 2L9FA 3G26A 2GYKA 1OR5A 3CCVP 1YHQP 2FQ2A 3DS4A 2AFDA 3CCMP 1IMPA 4U0EA 5DCKA 3CD6P 1DNYA 5HGLA 1K73Q 3H4EA 2FAEA 5HGOA 2KW2A 1KC8Q 2XV6A 2Z46A 2N50A 1GXGA 1UJZA 2P9XA 1E6JP 4XFYA
chains in the Genus database with same CATH topology
2VLPA 1GXHA 1EMVA 3GKLC 4F37A 4QKOA 2ERHA 1IMPA 2JAZA 2JBGA 1AYIA 5EW5E 3U43A 4UHPB 3GJNA 1E0HA 2VLQA 2GZJA 2GZGA 2JB0A 2VLOA 1UNKA 2NO8A 1MZ8A 2K0DX 1CEIA 1ZNVA 2GZEA 2WPTA 1FR2A 2GZIA 1BXIA 2GZFA 1GXGA 2GYKA 1UJZA 7CEIA 1IMQA 2K5XA 2VLNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VLP A;  1GXH A;  1EMV A;  3GKL C;  4F37 A;  4QKO A;  2ERH A;  1IMP A;  2JAZ A;  2JBG A;  1AYI A;  5EW5 E;  3U43 A;  4UHP B;  3GJN A;  1E0H A;  2VLQ A;  2GZJ A;  2GZG A;  2JB0 A;  2VLO A;  1UNK A;  2NO8 A;  1MZ8 A;  2K0D X;  1CEI A;  1ZNV A;  2GZE A;  2WPT A;  1FR2 A;  2GZI A;  1BXI A;  2GZF A;  1GXG A;  2GYK A;  1UJZ A;  7CEI A;  1IMQ A;  2K5X A;  2VLN A; 
#chains in the Genus database with same CATH topology
 1VQ5 P;  1VKU A;  2CG5 B;  5KP6 B;  1VQ7 P;  4H2X C;  2ROQ A;  5F2K A;  1E0H A;  1YJ9 P;  3CC2 P;  1M1K Q;  1UNK A;  2K0D X;  1NJI Q;  2OTL P;  1A43 A;  1VQP P;  2GDY A;  2GZF A;  2EG5 A;  2K5X A;  1ZMB A;  1VQM P;  3GKL C;  2EIA A;  3GZL A;  2BUO A;  4COP A;  1VQL P;  2MF4 A;  2FVF A;  2KG9 A;  2FQ0 A;  2OAR A;  3I56 P;  2EFJ A;  1BXI A;  2OTJ P;  2XZ0 D;  1EMV A;  2E1M A;  2FHS C;  1YIT P;  2GDX A;  4UHP B;  5I4T G;  1HQB A;  5JPA A;  5HGN A;  2PEO A;  2CGQ A;  3G21 A;  3MGE A;  3DS1 A;  3CCJ P;  1GPJ A;  3CCS P;  1NQ4 A;  2VLP A;  4U0A A;  2VSQ A;  2XT1 A;  4XRQ A;  4COC A;  1K8A Q;  1T8K A;  2EHT A;  2GZG A;  5HV8 A;  4WYM A;  1CEI A;  1Q82 Q;  1VQ9 P;  2KWL A;  2KG8 A;  2GDW A;  4R0M A;  2KGC A;  1QVF O;  2L4B A;  3GJN A;  3EJB A;  2KOO A;  2KOD A;  3G1I A;  4QNB A;  2ONT A;  1X3O A;  4XFX A;  2PNG A;  2KGD A;  1W2B O;  3RG6 C;  2M8N A;  2LTE A;  1GXH A;  4IZ6 A;  1VQ4 P;  4DG9 A;  2M8L A;  4HKG A;  2KOQ A;  1KQS O;  3Q20 A;  1Q7Y Q;  1Z6M A;  2GZE A;  2KOP A;  2LL8 A;  1YJW P;  3LMO A;  3VRL C;  3CCE P;  3RG2 A;  2PEM A;  3M1M A;  4QKO A;  2PEI A;  2FAD A;  2FAC A;  2JBG A;  2LF4 A;  3U43 A;  2K0X A;  2N6Z A;  3H0D A;  3NTE A;  4PWV B;  5HVC A;  2MR8 A;  1MZ8 A;  3G28 A;  2K92 A;  2K93 A;  2K94 A;  3DS0 A;  4PH1 A;  1FR2 A;  3LRY A;  2QNW A;  1Q86 Q;  2DGY A;  2LKI A;  2CNR A;  2AFE A;  1IMQ A;  2VLN A;  3HZQ A;  2N5H A;  4F37 A;  2KOS A;  3GZM A;  1KLP A;  1EIA A;  4GR2 A;  4U0B A;  1K9M Q;  4MRT C;  2K0Y A;  2VLQ A;  4U0D A;  2N98 A;  2PEK A;  5EJD A;  3EJD A;  4H2Y C;  1AF8 A;  3DS5 A;  1K30 A;  3DS2 A;  2BHV A;  1N8R Q;  3G1G A;  1HY8 A;  4BPH A;  4GR6 A;  5BS2 A;  2M8P A;  2LML A;  1S72 P;  2FVA A;  2AF8 A;  2Z44 A;  3CXC O;  3CPW O;  1VQK P;  2NO8 A;  3DPH A;  5KP7 B;  2KG6 A;  2CQ8 A;  4CA3 A;  3NY7 B;  1D1D A;  2WPT A;  4NEO A;  1DV5 A;  2KGA A;  2MVU A;  4BPG A;  1M90 Q;  2FVE A;  3CCR P;  1M6E X;  5F2N A;  3G71 P;  4H2W C;  2PEQ A;  3CC7 P;  1BAJ A;  1Q81 Q;  2QEX P;  2LOL A;  2JYG A;  2L0Q A;  3DTJ A;  2N6Y A;  2QA4 P;  5HGM A;  3G4S P;  1VQO P;  1EOQ A;  4IPY A;  2ERH A;  2JAZ A;  1M6N A;  3WBH A;  1ACP A;  3CMA P;  2GZJ A;  1VHN A;  1JJ2 O;  1VQ6 P;  3CCL P;  2XXM A;  2LPK A;  1QVG O;  2PEJ A;  2JU2 A;  2EHS A;  2N5I A;  4U0C A;  3P05 A;  2DNW A;  5BS1 A;  1M74 A;  1YJN P;  2KR5 A;  1KD1 Q;  2M5R A;  4U0F A;  1YIJ P;  2JB0 A;  4PXH B;  3E2D A;  1AUM A;  2AVA A;  2PEN A;  2Z45 A;  1VQN P;  2KOR A;  2MR7 A;  1L0I A;  3CE7 A;  1AYI A;  2KGE A;  3B5I A;  3OW2 O;  2VLO A;  2MVV A;  2LIW A;  2JGP A;  2X2B A;  2XZ1 C;  4BPF A;  3CME P;  3CC4 P;  3EJE A;  1RNI A;  4M0I A;  7CEI A;  2LIU A;  3DS3 A;  5F2O A;  2K2Q A;  2CWO A;  4XFZ A;  3G6E P;  1F80 D;  3CCU P;  3I55 P;  1RO0 A;  1A8O A;  1ZNV A;  1IUQ A;  2GZI A;  1RO2 A;  3H47 A;  4PH0 A;  3G0V A;  2JQ4 A;  4XRO A;  1YI2 P;  3G29 A;  2JYL A;  2JU1 A;  1L0H A;  1QRJ A;  2PY8 A;  2MD9 A;  5KP8 B;  2FQ1 A;  5EW5 E;  3B4Q A;  5CZD B;  2L6E A;  2JO0 A;  3CCQ P;  2MY5 A;  1VQ8 P;  2L22 A;  3HYB A;  2L9F A;  3G26 A;  2GYK A;  1OR5 A;  3CCV P;  1YHQ P;  2FQ2 A;  3DS4 A;  2AFD A;  3CCM P;  1IMP A;  4U0E A;  5DCK A;  3CD6 P;  1DNY A;  5HGL A;  1K73 Q;  3H4E A;  2FAE A;  5HGO A;  2KW2 A;  1KC8 Q;  2XV6 A;  2Z46 A;  2N50 A;  1GXG A;  1UJZ A;  2P9X A;  1E6J P;  4XFY A; 
#chains in the Genus database with same CATH homology
 2VLP A;  1GXH A;  1EMV A;  3GKL C;  4F37 A;  4QKO A;  2ERH A;  1IMP A;  2JAZ A;  2JBG A;  1AYI A;  5EW5 E;  3U43 A;  4UHP B;  3GJN A;  1E0H A;  2VLQ A;  2GZJ A;  2GZG A;  2JB0 A;  2VLO A;  1UNK A;  2NO8 A;  1MZ8 A;  2K0D X;  1CEI A;  1ZNV A;  2GZE A;  2WPT A;  1FR2 A;  2GZI A;  1BXI A;  2GZF A;  1GXG A;  2GYK A;  1UJZ A;  7CEI A;  1IMQ A;  2K5X A;  2VLN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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