3HZQA

Structure of a tetrameric mscl in an expanded intermediate state
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
94
structure length
94
Chain Sequence
MLKEFKEFALKGNVLDLAIAVVMGAAFNKIICSLVENIIMPLIGKIFGSVDFAKEWSFWGIKYGLFIQSVIDFIIIAFALFIFVKIANTLMKKE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of a tetrameric MscL in an expanded intermediate state.
pubmed doi rcsb
molecule tags Membrane protein
source organism Staphylococcus aureus subsp. aureus mw2
molecule keywords Large-conductance mechanosensitive channel
total genus 24
structure length 94
sequence length 94
ec nomenclature
pdb deposition date 2009-06-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.120 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A 3hzqA00
3HZQA 2OARA
chains in the Genus database with same CATH superfamily
3EJEA 3G4SP 4COCA 2AFDA 1QVFO 5F2NA 1VQMP 2Z45A 1JJ2O 2GDYA 5HVCA 5F2KA 1VQ7P 2N98A 1M90Q 2ERHA 2M8PA 2EIAA 1L0HA 2JYGA 1RNIA 4DG9A 1ZMBA 2FVFA 3DS4A 3GKLC 4H2XC 2BHVA 1MZ8A 1HQBA 2PEOA 1EOQA 2KOOA 1YJWP 2KW2A 3RG2A 5BS2A 2KGEA 5HGLA 4MRTC 4HKGA 2K0YA 4M0IA 1YJNP 4PH1A 1AF8A 2AF8A 4U0BA 2N6ZA 2PENA 1AYIA 2MR7A 2FADA 2FQ2A 1FR2A 3CC4P 2L4BA 1VQLP 2FVEA 1VQPP 4BPHA 5BS1A 5HGMA 3GZMA 1A8OA 4UHPB 3EJDA 2PEQA 1BXIA 2PEJA 3U43A 2XXMA 2EHTA 4U0CA 2KOSA 2P9XA 2L22A 4GR2A 3RG6C 2JQ4A 4NEOA 2N6YA 1DV5A 3CC7P 3G1IA 5EW5E 2JB0A 3B5IA 4U0DA 2FVAA 2FAEA 2K93A 3CCJP 1ACPA 1IMQA 1ZNVA 2AVAA 2PEMA 2VLNA 1Q81Q 1K8AQ 2MF4A 2XZ0D 1KLPA 2VLPA 3G26A 4U0AA 3B4QA 1UJZA 1Z6MA 1E0HA 2GYKA 2DGYA 4PH0A 2GZFA 3I55P 2K94A 3E2DA 2EG5A 2FQ1A 3M1MA 5CZDB 1RO0A 2VLOA 1DNYA 2ROQA 2K2QA 1K30A 2XV6A 3CXCO 4IZ6A 1T8KA 2N5HA 1YHQP 4PWVB 3CCLP 3I56P 3MGEA 2FACA 5HGNA 2VSQA 2M8NA 2OARA 5DCKA 3DS0A 2AFEA 1Q86Q 4BPFA 3H47A 1W2BO 1QRJA 2KGDA 3DTJA 2KR5A 1Q7YQ 1KC8Q 3DS5A 1A43A 2KWLA 1VQOP 1YITP 2KGCA 1K9MQ 1KQSO 1BAJA 2PY8A 2N50A 2JU1A 1GXGA 2GZGA 1YI2P 1RO2A 4CA3A 2MVUA 3CCSP 2X2BA 2GDXA 4IPYA 3G21A 1VQ6P 3LRYA 1D1DA 2M8LA 1CEIA 3DS3A 1GXHA 2JGPA 2KGAA 3G0VA 1E6JP 2GZEA 3CCMP 4QNBA 1IMPA 2CNRA 3G71P 2JYLA 2GZIA 3EJBA 1VQKP 4R0MA 2QA4P 2LPKA 2QEXP 4U0EA 3GJNA 3HYBA 1N8RQ 2K0DX 2GZJA 3CMEP 2XZ1C 3CMAP 2EHSA 2KG8A 2NO8A 3G29A 1VKUA 2LMLA 4XROA 5HV8A 3OW2O 3WBHA 3P05A 3CPWO 4GR6A 2E1MA 2ONTA 2JAZA 3G28A 2WPTA 3NTEA 1K73Q 4U0FA 2DNWA 3NY7B 1NJIQ 4XFZA 2VLQA 2LTEA 2N5IA 2KORA 3CCUP 2FQ0A 1HY8A 4XFYA 4BPGA 3VRLC 3CCEP 1Q82Q 7CEIA 3DS1A 1KD1Q 3GZLA 5JPAA 3DPHA 1VQ8P 2FHSC 2K5XA 3CCQP 2K0XA 1OR5A 2KOQA 5I4TG 5KP6B 1AUMA 5KP7B 1IUQA 1M6NA 2LKIA 3CE7A 5HGOA 2CWOA 3CC2P 5EJDA 2CG5B 2MD9A 1EMVA 2PEKA 1M74A 1UNKA 4H2WC 2QNWA 1VQ4P 2PNGA 2L9FA 1M6EX 2L0QA 5KP8B 1VQNP 3H0DA 4XRQA 1YJ9P 1VHNA 2MY5A 2PEIA 1QVGO 1EIAA 2L6EA 2BUOA 2LL8A 1L0IA 2CGQA 2JO0A 2LIWA 2JU2A 4F37A 3HZQA 2KG6A 2EFJA 3H4EA 2Z46A 2KOPA 2GDWA 2Z44A 3CCVP 1GPJA 2CQ8A 4H2YC 2XT1A 1VQ5P 2KODA 4XFXA 1S72P 2MR8A 3CCRP 2MVVA 2KG9A 3CD6P 1VQ9P 2JBGA 1YIJP 2LOLA 3G6EP 1F80D 1X3OA 3DS2A 2LIUA 3LMOA 1M1KQ 4QKOA 2M5RA 4PXHB 5F2OA 2OTLP 2OTJP 1NQ4A 4COPA 3Q20A 3G1GA 4WYMA 2K92A 2LF4A
chains in the Genus database with same CATH topology
3CCQP 3G4SP 3CC7P 3G1IA 4COCA 3CCSP 5I4TG 3B5IA 1QVFO 4U0DA 5F2NA 4IPYA 1VQMP 3G21A 1AUMA 2Z45A 1JJ2O 3CCJP 1IUQA 1VQ6P 1M6NA 3LRYA 1D1DA 2M8LA 5HGOA 5F2KA 3DS3A 2CWOA 1VQ7P 2PEMA 1Q81Q 3CC2P 1K8AQ 1M90Q 2M8PA 3G0VA 1E6JP 2EIAA 2JYGA 2PEKA 3CCMP 1M74A 1RNIA 3G26A 4U0AA 1ZMBA 4QNBA 1VQ4P 1M6EX 3DS4A 2DGYA 4PH0A 1VQNP 3H0DA 3G71P 2JYLA 4XRQA 1YJ9P 3I55P 2BHVA 1VQKP 3E2DA 2QA4P 2EG5A 3M1MA 2QEXP 4U0EA 2PEOA 2PEIA 1EOQA 1QVGO 1EIAA 1RO0A 2BUOA 2L6EA 1YJWP 5BS2A 2JO0A 5HGLA 1K30A 2XV6A 3CXCO 4M0IA 3HYBA 1N8RQ 1YJNP 1YHQP 4PH1A 3CMEP 3CMAP 3CCLP 4U0BA 3I56P 3HZQA 3G29A 2EFJA 3H4EA 2Z46A 3MGEA 4XROA 5HGNA 2PENA 2M8NA 2OARA 3OW2O 2Z44A 3CCVP 5DCKA 3WBHA 3DS0A 2XT1A 1VQ5P 2KODA 4XFXA 3P05A 1S72P 3CPWO 4GR6A 1Q86Q 2E1MA 2ONTA 3CCRP 3CD6P 1VQ9P 3H47A 3G28A 1W2BO 3CC4P 1QRJA 3DTJA 3NTEA 1K73Q 4U0FA 1Q7YQ 1NJIQ 1KC8Q 3DS5A 4XFZA 1VQLP 1A43A 1YIJP 3G6EP 1VQPP 3DS2A 5BS1A 1VQOP 1YITP 5HGMA 1A8OA 3CCUP 2PEQA 1M1KQ 4XFYA 1K9MQ 1KQSO 1BAJA 3VRLC 2PY8A 3CCEP 1Q82Q 2PEJA 2XXMA 3DS1A 4U0CA 5F2OA 1KD1Q 5JPAA 2P9XA 3DPHA 2OTLP 2OTJP 4COPA 1VQ8P 4GR2A 3RG6C 3Q20A 1YI2P 3G1GA 4WYMA 2LF4A 1RO2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HZQ A;  2OAR A; 
#chains in the Genus database with same CATH topology
 3EJE A;  3G4S P;  4COC A;  2AFD A;  1QVF O;  5F2N A;  1VQM P;  2Z45 A;  1JJ2 O;  2GDY A;  5HVC A;  5F2K A;  1VQ7 P;  2N98 A;  1M90 Q;  2ERH A;  2M8P A;  2EIA A;  1L0H A;  2JYG A;  1RNI A;  4DG9 A;  1ZMB A;  2FVF A;  3DS4 A;  3GKL C;  4H2X C;  2BHV A;  1MZ8 A;  1HQB A;  2PEO A;  1EOQ A;  2KOO A;  1YJW P;  2KW2 A;  3RG2 A;  5BS2 A;  2KGE A;  5HGL A;  4MRT C;  4HKG A;  2K0Y A;  4M0I A;  1YJN P;  4PH1 A;  1AF8 A;  2AF8 A;  4U0B A;  2N6Z A;  2PEN A;  1AYI A;  2MR7 A;  2FAD A;  2FQ2 A;  1FR2 A;  3CC4 P;  2L4B A;  1VQL P;  2FVE A;  1VQP P;  4BPH A;  5BS1 A;  5HGM A;  3GZM A;  1A8O A;  4UHP B;  3EJD A;  2PEQ A;  1BXI A;  2PEJ A;  3U43 A;  2XXM A;  2EHT A;  4U0C A;  2KOS A;  2P9X A;  2L22 A;  4GR2 A;  3RG6 C;  2JQ4 A;  4NEO A;  2N6Y A;  1DV5 A;  3CC7 P;  3G1I A;  5EW5 E;  2JB0 A;  3B5I A;  4U0D A;  2FVA A;  2FAE A;  2K93 A;  3CCJ P;  1ACP A;  1IMQ A;  1ZNV A;  2AVA A;  2PEM A;  2VLN A;  1Q81 Q;  1K8A Q;  2MF4 A;  2XZ0 D;  1KLP A;  2VLP A;  3G26 A;  4U0A A;  3B4Q A;  1UJZ A;  1Z6M A;  1E0H A;  2GYK A;  2DGY A;  4PH0 A;  2GZF A;  3I55 P;  2K94 A;  3E2D A;  2EG5 A;  2FQ1 A;  3M1M A;  5CZD B;  1RO0 A;  2VLO A;  1DNY A;  2ROQ A;  2K2Q A;  1K30 A;  2XV6 A;  3CXC O;  4IZ6 A;  1T8K A;  2N5H A;  1YHQ P;  4PWV B;  3CCL P;  3I56 P;  3MGE A;  2FAC A;  5HGN A;  2VSQ A;  2M8N A;  2OAR A;  5DCK A;  3DS0 A;  2AFE A;  1Q86 Q;  4BPF A;  3H47 A;  1W2B O;  1QRJ A;  2KGD A;  3DTJ A;  2KR5 A;  1Q7Y Q;  1KC8 Q;  3DS5 A;  1A43 A;  2KWL A;  1VQO P;  1YIT P;  2KGC A;  1K9M Q;  1KQS O;  1BAJ A;  2PY8 A;  2N50 A;  2JU1 A;  1GXG A;  2GZG A;  1YI2 P;  1RO2 A;  4CA3 A;  2MVU A;  3CCS P;  2X2B A;  2GDX A;  4IPY A;  3G21 A;  1VQ6 P;  3LRY A;  1D1D A;  2M8L A;  1CEI A;  3DS3 A;  1GXH A;  2JGP A;  2KGA A;  3G0V A;  1E6J P;  2GZE A;  3CCM P;  4QNB A;  1IMP A;  2CNR A;  3G71 P;  2JYL A;  2GZI A;  3EJB A;  1VQK P;  4R0M A;  2QA4 P;  2LPK A;  2QEX P;  4U0E A;  3GJN A;  3HYB A;  1N8R Q;  2K0D X;  2GZJ A;  3CME P;  2XZ1 C;  3CMA P;  2EHS A;  2KG8 A;  2NO8 A;  3G29 A;  1VKU A;  2LML A;  4XRO A;  5HV8 A;  3OW2 O;  3WBH A;  3P05 A;  3CPW O;  4GR6 A;  2E1M A;  2ONT A;  2JAZ A;  3G28 A;  2WPT A;  3NTE A;  1K73 Q;  4U0F A;  2DNW A;  3NY7 B;  1NJI Q;  4XFZ A;  2VLQ A;  2LTE A;  2N5I A;  2KOR A;  3CCU P;  2FQ0 A;  1HY8 A;  4XFY A;  4BPG A;  3VRL C;  3CCE P;  1Q82 Q;  7CEI A;  3DS1 A;  1KD1 Q;  3GZL A;  5JPA A;  3DPH A;  1VQ8 P;  2FHS C;  2K5X A;  3CCQ P;  2K0X A;  1OR5 A;  2KOQ A;  5I4T G;  5KP6 B;  1AUM A;  5KP7 B;  1IUQ A;  1M6N A;  2LKI A;  3CE7 A;  5HGO A;  2CWO A;  3CC2 P;  5EJD A;  2CG5 B;  2MD9 A;  1EMV A;  2PEK A;  1M74 A;  1UNK A;  4H2W C;  2QNW A;  1VQ4 P;  2PNG A;  2L9F A;  1M6E X;  2L0Q A;  5KP8 B;  1VQN P;  3H0D A;  4XRQ A;  1YJ9 P;  1VHN A;  2MY5 A;  2PEI A;  1QVG O;  1EIA A;  2L6E A;  2BUO A;  2LL8 A;  1L0I A;  2CGQ A;  2JO0 A;  2LIW A;  2JU2 A;  4F37 A;  3HZQ A;  2KG6 A;  2EFJ A;  3H4E A;  2Z46 A;  2KOP A;  2GDW A;  2Z44 A;  3CCV P;  1GPJ A;  2CQ8 A;  4H2Y C;  2XT1 A;  1VQ5 P;  2KOD A;  4XFX A;  1S72 P;  2MR8 A;  3CCR P;  2MVV A;  2KG9 A;  3CD6 P;  1VQ9 P;  2JBG A;  1YIJ P;  2LOL A;  3G6E P;  1F80 D;  1X3O A;  3DS2 A;  2LIU A;  3LMO A;  1M1K Q;  4QKO A;  2M5R A;  4PXH B;  5F2O A;  2OTL P;  2OTJ P;  1NQ4 A;  4COP A;  3Q20 A;  3G1G A;  4WYM A;  2K92 A;  2LF4 A; 
#chains in the Genus database with same CATH homology
 3CCQ P;  3G4S P;  3CC7 P;  3G1I A;  4COC A;  3CCS P;  5I4T G;  3B5I A;  1QVF O;  4U0D A;  5F2N A;  4IPY A;  1VQM P;  3G21 A;  1AUM A;  2Z45 A;  1JJ2 O;  3CCJ P;  1IUQ A;  1VQ6 P;  1M6N A;  3LRY A;  1D1D A;  2M8L A;  5HGO A;  5F2K A;  3DS3 A;  2CWO A;  1VQ7 P;  2PEM A;  1Q81 Q;  3CC2 P;  1K8A Q;  1M90 Q;  2M8P A;  3G0V A;  1E6J P;  2EIA A;  2JYG A;  2PEK A;  3CCM P;  1M74 A;  1RNI A;  3G26 A;  4U0A A;  1ZMB A;  4QNB A;  1VQ4 P;  1M6E X;  3DS4 A;  2DGY A;  4PH0 A;  1VQN P;  3H0D A;  3G71 P;  2JYL A;  4XRQ A;  1YJ9 P;  3I55 P;  2BHV A;  1VQK P;  3E2D A;  2QA4 P;  2EG5 A;  3M1M A;  2QEX P;  4U0E A;  2PEO A;  2PEI A;  1EOQ A;  1QVG O;  1EIA A;  1RO0 A;  2BUO A;  2L6E A;  1YJW P;  5BS2 A;  2JO0 A;  5HGL A;  1K30 A;  2XV6 A;  3CXC O;  4M0I A;  3HYB A;  1N8R Q;  1YJN P;  1YHQ P;  4PH1 A;  3CME P;  3CMA P;  3CCL P;  4U0B A;  3I56 P;  3HZQ A;  3G29 A;  2EFJ A;  3H4E A;  2Z46 A;  3MGE A;  4XRO A;  5HGN A;  2PEN A;  2M8N A;  2OAR A;  3OW2 O;  2Z44 A;  3CCV P;  5DCK A;  3WBH A;  3DS0 A;  2XT1 A;  1VQ5 P;  2KOD A;  4XFX A;  3P05 A;  1S72 P;  3CPW O;  4GR6 A;  1Q86 Q;  2E1M A;  2ONT A;  3CCR P;  3CD6 P;  1VQ9 P;  3H47 A;  3G28 A;  1W2B O;  3CC4 P;  1QRJ A;  3DTJ A;  3NTE A;  1K73 Q;  4U0F A;  1Q7Y Q;  1NJI Q;  1KC8 Q;  3DS5 A;  4XFZ A;  1VQL P;  1A43 A;  1YIJ P;  3G6E P;  1VQP P;  3DS2 A;  5BS1 A;  1VQO P;  1YIT P;  5HGM A;  1A8O A;  3CCU P;  2PEQ A;  1M1K Q;  4XFY A;  1K9M Q;  1KQS O;  1BAJ A;  3VRL C;  2PY8 A;  3CCE P;  1Q82 Q;  2PEJ A;  2XXM A;  3DS1 A;  4U0C A;  5F2O A;  1KD1 Q;  5JPA A;  2P9X A;  3DPH A;  2OTL P;  2OTJ P;  4COP A;  1VQ8 P;  4GR2 A;  3RG6 C;  3Q20 A;  1YI2 P;  3G1G A;  4WYM A;  2LF4 A;  1RO2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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