5EJDA

The crystal structure of holo t3ct
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
75
structure length
75
Chain Sequence
KQLSTDAERELANIWATVLDIPIGTISASDNFFFRGGHSIDAMKASALGRAAGMSFGVADIFDHPVLSELASVAV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of nonribosomal peptide macrocyclization in fungi
pubmed doi rcsb
molecule tags Biosynthetic protein
source organism Penicillium aethiopicum
molecule keywords TqaA
total genus 23
structure length 75
sequence length 75
chains with identical sequence C, E, G, I, K, M, O
ec nomenclature
pdb deposition date 2015-11-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00550 PP-binding Phosphopantetheine attachment site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.10 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A ACP-like 5ejdA00
2FADA 3EJDA 2FVAA 4BPHA 1L0HA 1OR5A 3EJBA 2KG9A 4R0MA 2FACA 2GDXA 4HKGA 2EHSA 1DV5A 1NQ4A 2KG6A 4NEOA 1X3OA 2LIUA 2JQ4A 4MRTC 2MR7A 5CZDB 2ROQA 2K0XA 2JU1A 2KG8A 2FQ1A 2AF8A 5HV8A 2GDYA 1F80D 5KP8B 2K2QA 2MVUA 2N5IA 2QNWA 2AVAA 2FAEA 3NY7B 3EJEA 2LIWA 2FVFA 2LMLA 2GDWA 2KOPA 1ACPA 2VSQA 1AF8A 2K94A 2K92A 5KP6B 2CNRA 2JGPA 2MR8A 4IZ6A 1VKUA 2N98A 2XZ0D 3GZLA 4BPGA 5KP7B 2KGAA 2N50A 2KORA 2FQ0A 2JU2A 2KOOA 2KW2A 2KGEA 2KR5A 4PXHB 2K93A 2DNWA 3CE7A 2CQ8A 2L4BA 2N6ZA 5HVCA 2K0YA 3GZMA 1T8KA 3LMOA 2LOLA 2N6YA 5EJDA 2N5HA 1HQBA 2MD9A 2FVEA 2CG5B 2LTEA 2KOQA 4H2WC 2FHSC 2KWLA 2KGCA 1HY8A 2CGQA 1L0IA 2KGDA 2PNGA 2AFEA 2L22A 4H2XC 2AFDA 2KOSA 3RG2A 2MY5A 2LPKA 2EHTA 2X2BA 2LL8A 4CA3A 2L0QA 1KLPA 4H2YC 2MF4A 1DNYA 2XZ1C 2L9FA 2FQ2A 4BPFA 2MVVA 4DG9A 2LKIA 4PWVB 2M5RA
chains in the Genus database with same CATH superfamily
2FADA 1W2BO 1Q7YQ 1QRJA 2KG9A 1EIAA 2GZEA 1EOQA 3CC2P 1GXHA 3G29A 1NQ4A 1M1KQ 5JPAA 2JQ4A 3G28A 5DCKA 1YHQP 2AF8A 3CCLP 3LRYA 3WBHA 2PEMA 2GDYA 1F80D 3GJNA 5KP8B 1KQSO 4WYMA 3DPHA 2AVAA 3NY7B 2GZFA 1IUQA 1VQKP 2GDWA 2VLQA 1QVFO 1GPJA 2OTLP 2K94A 1YITP 7CEIA 1KC8Q 2K92A 1S72P 3OW2O 1UNKA 3CCVP 1BXIA 2Z44A 4QKOA 1VQ4P 2DGYA 1D1DA 5HGNA 2KW2A 4PH1A 4PXHB 3CE7A 2CQ8A 2PEIA 5F2OA 2JBGA 1RO2A 2EG5A 5EJDA 1YI2P 3CCSP 1HQBA 2MD9A 2FHSC 2KWLA 4XRQA 1K8AQ 2KGDA 2L22A 3Q20A 2AFDA 3CXCO 2KOSA 2MY5A 1RO0A 1AYIA 2M8NA 2BUOA 1Q81Q 5HGMA 4BPFA 2LKIA 4PWVB 4GR6A 2GZJA 3EJDA 4BPHA 2E1MA 4U0EA 1OR5A 1ZMBA 3EJBA 1VQLP 2Z45A 2FACA 1VQOP 2JYLA 2P9XA 1DV5A 2JO0A 3CCUP 2LIUA 3CCEP 5CZDB 2K0XA 2JU1A 2KG8A 5HV8A 2JAZA 3G1GA 2MVUA 3DS4A 2QNWA 1A43A 4M0IA 4IPYA 1ZNVA 3H47A 3G1IA 3RG6C 2CWOA 2KOPA 3G71P 3U43A 3CCRP 3CC7P 2ERHA 5I4TG 3H0DA 2CNRA 1QVGO 2JGPA 1M74A 1VKUA 2PEOA 2XZ0D 1GXGA 5KP7B 5HGOA 3HZQA 3GKLC 2GZGA 3CPWO 2GZIA 2JU2A 3DS5A 2KGEA 2Z46A 3H4EA 5HVCA 1IMPA 3LMOA 1MZ8A 2N6YA 5EW5E 2XT1A 1VHNA 2VLPA 5F2NA 2LTEA 1VQ9P 3CCJP 2KGCA 3G4SP 3G21A 1VQNP 1HY8A 2CGQA 1L0IA 5BS2A 2PNGA 1M6EX 3RG2A 3NTEA 1VQ8P 2MF4A 3DS1A 2L9FA 3DS2A 2QEXP 1L0HA 1VQ5P 2WPTA 3I55P 4F37A 2M8LA 2VLOA 4HKGA 2EHSA 2KG6A 4NEOA 1X3OA 1VQ6P 2OTJP 4MRTC 1FR2A 2K2QA 2VLNA 2N5IA 4COPA 3CMAP 2FAEA 3EJEA 2PEQA 2LIWA 1ACPA 2VSQA 2GYKA 1E6JP 4COCA 2MR8A 2OARA 5BS1A 4PH0A 2N98A 3G6EP 2KGAA 1YJWP 2N50A 1KD1Q 3CD6P 2KORA 4UHPB 2FQ0A 1YJNP 2KR5A 2K0DX 1M90Q 2K93A 2DNWA 2L4BA 2K0YA 3GZMA 3CCQP 2PENA 2QA4P 3B4QA 1BAJA 2FVEA 2KOQA 4H2WC 1CEIA 1Q82Q 1RNIA 2K5XA 4U0FA 1K9MQ 2XV6A 2EHTA 2LL8A 4CA3A 2L0QA 1KLPA 1NJIQ 2XZ1C 5HGLA 1A8OA 2FQ2A 1JJ2O 3DS3A 4U0DA 2EIAA 1EMVA 2FVAA 4U0CA 3MGEA 2ONTA 1UJZA 3CC4P 1M6NA 4U0BA 1K73Q 2PY8A 4XROA 4R0MA 2GDXA 2XXMA 3B5IA 1N8RQ 3M1MA 2MR7A 2ROQA 3DS0A 2FQ1A 3G26A 2LF4A 3I56P 1E0HA 1AUMA 2FVFA 2LMLA 4XFZA 1AF8A 2JB0A 2NO8A 3DTJA 5KP6B 2JYGA 4IZ6A 3VRLC 3HYBA 3GZLA 4BPGA 2PEJA 3P05A 1VQ7P 1Q86Q 2KOOA 1VQPP 2M8PA 4U0AA 4XFXA 2N6ZA 1T8KA 1K30A 2LOLA 2L6EA 1YIJP 2N5HA 3G0VA 4GR2A 1YJ9P 2CG5B 1VQMP 3CMEP 1Z6MA 4QNBA 2AFEA 4H2XC 2PEKA 1IMQA 2BHVA 2LPKA 2X2BA 2EFJA 4H2YC 4XFYA 3CCMP 1DNYA 5F2KA 3E2DA 2KODA 2MVVA 4DG9A 2M5RA
chains in the Genus database with same CATH topology
2FADA 3EJDA 2FVAA 4BPHA 1L0HA 1OR5A 3EJBA 2KG9A 4R0MA 2FACA 2GDXA 4HKGA 2EHSA 1DV5A 1NQ4A 2KG6A 4NEOA 1X3OA 2LIUA 2JQ4A 4MRTC 2MR7A 5CZDB 2ROQA 2K0XA 2JU1A 2KG8A 2FQ1A 2AF8A 5HV8A 2GDYA 1F80D 5KP8B 2K2QA 2MVUA 2N5IA 2QNWA 2AVAA 2FAEA 3NY7B 3EJEA 2LIWA 2FVFA 2LMLA 2GDWA 2KOPA 1ACPA 2VSQA 1AF8A 2K94A 2K92A 5KP6B 2CNRA 2JGPA 2MR8A 4IZ6A 1VKUA 2N98A 2XZ0D 3GZLA 4BPGA 5KP7B 2KGAA 2N50A 2KORA 2FQ0A 2JU2A 2KOOA 2KW2A 2KGEA 2KR5A 4PXHB 2K93A 2DNWA 3CE7A 2CQ8A 2L4BA 2N6ZA 5HVCA 2K0YA 3GZMA 1T8KA 3LMOA 2LOLA 2N6YA 5EJDA 2N5HA 1HQBA 2MD9A 2FVEA 2CG5B 2LTEA 2KOQA 4H2WC 2FHSC 2KWLA 2KGCA 1HY8A 2CGQA 1L0IA 2KGDA 2PNGA 2AFEA 2L22A 4H2XC 2AFDA 2KOSA 3RG2A 2MY5A 2LPKA 2EHTA 2X2BA 2LL8A 4CA3A 2L0QA 1KLPA 4H2YC 2MF4A 1DNYA 2XZ1C 2L9FA 2FQ2A 4BPFA 2MVVA 4DG9A 2LKIA 4PWVB 2M5RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FAD A;  3EJD A;  2FVA A;  4BPH A;  1L0H A;  1OR5 A;  3EJB A;  2KG9 A;  4R0M A;  2FAC A;  2GDX A;  4HKG A;  2EHS A;  1DV5 A;  1NQ4 A;  2KG6 A;  4NEO A;  1X3O A;  2LIU A;  2JQ4 A;  4MRT C;  2MR7 A;  5CZD B;  2ROQ A;  2K0X A;  2JU1 A;  2KG8 A;  2FQ1 A;  2AF8 A;  5HV8 A;  2GDY A;  1F80 D;  5KP8 B;  2K2Q A;  2MVU A;  2N5I A;  2QNW A;  2AVA A;  2FAE A;  3NY7 B;  3EJE A;  2LIW A;  2FVF A;  2LML A;  2GDW A;  2KOP A;  1ACP A;  2VSQ A;  1AF8 A;  2K94 A;  2K92 A;  5KP6 B;  2CNR A;  2JGP A;  2MR8 A;  4IZ6 A;  1VKU A;  2N98 A;  2XZ0 D;  3GZL A;  4BPG A;  5KP7 B;  2KGA A;  2N50 A;  2KOR A;  2FQ0 A;  2JU2 A;  2KOO A;  2KW2 A;  2KGE A;  2KR5 A;  4PXH B;  2K93 A;  2DNW A;  3CE7 A;  2CQ8 A;  2L4B A;  2N6Z A;  5HVC A;  2K0Y A;  3GZM A;  1T8K A;  3LMO A;  2LOL A;  2N6Y A;  5EJD A;  2N5H A;  1HQB A;  2MD9 A;  2FVE A;  2CG5 B;  2LTE A;  2KOQ A;  4H2W C;  2FHS C;  2KWL A;  2KGC A;  1HY8 A;  2CGQ A;  1L0I A;  2KGD A;  2PNG A;  2AFE A;  2L22 A;  4H2X C;  2AFD A;  2KOS A;  3RG2 A;  2MY5 A;  2LPK A;  2EHT A;  2X2B A;  2LL8 A;  4CA3 A;  2L0Q A;  1KLP A;  4H2Y C;  2MF4 A;  1DNY A;  2XZ1 C;  2L9F A;  2FQ2 A;  4BPF A;  2MVV A;  4DG9 A;  2LKI A;  4PWV B;  2M5R A; 
#chains in the Genus database with same CATH topology
 2FAD A;  1W2B O;  1Q7Y Q;  1QRJ A;  2KG9 A;  1EIA A;  2GZE A;  1EOQ A;  3CC2 P;  1GXH A;  3G29 A;  1NQ4 A;  1M1K Q;  5JPA A;  2JQ4 A;  3G28 A;  5DCK A;  1YHQ P;  2AF8 A;  3CCL P;  3LRY A;  3WBH A;  2PEM A;  2GDY A;  1F80 D;  3GJN A;  5KP8 B;  1KQS O;  4WYM A;  3DPH A;  2AVA A;  3NY7 B;  2GZF A;  1IUQ A;  1VQK P;  2GDW A;  2VLQ A;  1QVF O;  1GPJ A;  2OTL P;  2K94 A;  1YIT P;  7CEI A;  1KC8 Q;  2K92 A;  1S72 P;  3OW2 O;  1UNK A;  3CCV P;  1BXI A;  2Z44 A;  4QKO A;  1VQ4 P;  2DGY A;  1D1D A;  5HGN A;  2KW2 A;  4PH1 A;  4PXH B;  3CE7 A;  2CQ8 A;  2PEI A;  5F2O A;  2JBG A;  1RO2 A;  2EG5 A;  5EJD A;  1YI2 P;  3CCS P;  1HQB A;  2MD9 A;  2FHS C;  2KWL A;  4XRQ A;  1K8A Q;  2KGD A;  2L22 A;  3Q20 A;  2AFD A;  3CXC O;  2KOS A;  2MY5 A;  1RO0 A;  1AYI A;  2M8N A;  2BUO A;  1Q81 Q;  5HGM A;  4BPF A;  2LKI A;  4PWV B;  4GR6 A;  2GZJ A;  3EJD A;  4BPH A;  2E1M A;  4U0E A;  1OR5 A;  1ZMB A;  3EJB A;  1VQL P;  2Z45 A;  2FAC A;  1VQO P;  2JYL A;  2P9X A;  1DV5 A;  2JO0 A;  3CCU P;  2LIU A;  3CCE P;  5CZD B;  2K0X A;  2JU1 A;  2KG8 A;  5HV8 A;  2JAZ A;  3G1G A;  2MVU A;  3DS4 A;  2QNW A;  1A43 A;  4M0I A;  4IPY A;  1ZNV A;  3H47 A;  3G1I A;  3RG6 C;  2CWO A;  2KOP A;  3G71 P;  3U43 A;  3CCR P;  3CC7 P;  2ERH A;  5I4T G;  3H0D A;  2CNR A;  1QVG O;  2JGP A;  1M74 A;  1VKU A;  2PEO A;  2XZ0 D;  1GXG A;  5KP7 B;  5HGO A;  3HZQ A;  3GKL C;  2GZG A;  3CPW O;  2GZI A;  2JU2 A;  3DS5 A;  2KGE A;  2Z46 A;  3H4E A;  5HVC A;  1IMP A;  3LMO A;  1MZ8 A;  2N6Y A;  5EW5 E;  2XT1 A;  1VHN A;  2VLP A;  5F2N A;  2LTE A;  1VQ9 P;  3CCJ P;  2KGC A;  3G4S P;  3G21 A;  1VQN P;  1HY8 A;  2CGQ A;  1L0I A;  5BS2 A;  2PNG A;  1M6E X;  3RG2 A;  3NTE A;  1VQ8 P;  2MF4 A;  3DS1 A;  2L9F A;  3DS2 A;  2QEX P;  1L0H A;  1VQ5 P;  2WPT A;  3I55 P;  4F37 A;  2M8L A;  2VLO A;  4HKG A;  2EHS A;  2KG6 A;  4NEO A;  1X3O A;  1VQ6 P;  2OTJ P;  4MRT C;  1FR2 A;  2K2Q A;  2VLN A;  2N5I A;  4COP A;  3CMA P;  2FAE A;  3EJE A;  2PEQ A;  2LIW A;  1ACP A;  2VSQ A;  2GYK A;  1E6J P;  4COC A;  2MR8 A;  2OAR A;  5BS1 A;  4PH0 A;  2N98 A;  3G6E P;  2KGA A;  1YJW P;  2N50 A;  1KD1 Q;  3CD6 P;  2KOR A;  4UHP B;  2FQ0 A;  1YJN P;  2KR5 A;  2K0D X;  1M90 Q;  2K93 A;  2DNW A;  2L4B A;  2K0Y A;  3GZM A;  3CCQ P;  2PEN A;  2QA4 P;  3B4Q A;  1BAJ A;  2FVE A;  2KOQ A;  4H2W C;  1CEI A;  1Q82 Q;  1RNI A;  2K5X A;  4U0F A;  1K9M Q;  2XV6 A;  2EHT A;  2LL8 A;  4CA3 A;  2L0Q A;  1KLP A;  1NJI Q;  2XZ1 C;  5HGL A;  1A8O A;  2FQ2 A;  1JJ2 O;  3DS3 A;  4U0D A;  2EIA A;  1EMV A;  2FVA A;  4U0C A;  3MGE A;  2ONT A;  1UJZ A;  3CC4 P;  1M6N A;  4U0B A;  1K73 Q;  2PY8 A;  4XRO A;  4R0M A;  2GDX A;  2XXM A;  3B5I A;  1N8R Q;  3M1M A;  2MR7 A;  2ROQ A;  3DS0 A;  2FQ1 A;  3G26 A;  2LF4 A;  3I56 P;  1E0H A;  1AUM A;  2FVF A;  2LML A;  4XFZ A;  1AF8 A;  2JB0 A;  2NO8 A;  3DTJ A;  5KP6 B;  2JYG A;  4IZ6 A;  3VRL C;  3HYB A;  3GZL A;  4BPG A;  2PEJ A;  3P05 A;  1VQ7 P;  1Q86 Q;  2KOO A;  1VQP P;  2M8P A;  4U0A A;  4XFX A;  2N6Z A;  1T8K A;  1K30 A;  2LOL A;  2L6E A;  1YIJ P;  2N5H A;  3G0V A;  4GR2 A;  1YJ9 P;  2CG5 B;  1VQM P;  3CME P;  1Z6M A;  4QNB A;  2AFE A;  4H2X C;  2PEK A;  1IMQ A;  2BHV A;  2LPK A;  2X2B A;  2EFJ A;  4H2Y C;  4XFY A;  3CCM P;  1DNY A;  5F2K A;  3E2D A;  2KOD A;  2MVV A;  4DG9 A;  2M5R A; 
#chains in the Genus database with same CATH homology
 2FAD A;  3EJD A;  2FVA A;  4BPH A;  1L0H A;  1OR5 A;  3EJB A;  2KG9 A;  4R0M A;  2FAC A;  2GDX A;  4HKG A;  2EHS A;  1DV5 A;  1NQ4 A;  2KG6 A;  4NEO A;  1X3O A;  2LIU A;  2JQ4 A;  4MRT C;  2MR7 A;  5CZD B;  2ROQ A;  2K0X A;  2JU1 A;  2KG8 A;  2FQ1 A;  2AF8 A;  5HV8 A;  2GDY A;  1F80 D;  5KP8 B;  2K2Q A;  2MVU A;  2N5I A;  2QNW A;  2AVA A;  2FAE A;  3NY7 B;  3EJE A;  2LIW A;  2FVF A;  2LML A;  2GDW A;  2KOP A;  1ACP A;  2VSQ A;  1AF8 A;  2K94 A;  2K92 A;  5KP6 B;  2CNR A;  2JGP A;  2MR8 A;  4IZ6 A;  1VKU A;  2N98 A;  2XZ0 D;  3GZL A;  4BPG A;  5KP7 B;  2KGA A;  2N50 A;  2KOR A;  2FQ0 A;  2JU2 A;  2KOO A;  2KW2 A;  2KGE A;  2KR5 A;  4PXH B;  2K93 A;  2DNW A;  3CE7 A;  2CQ8 A;  2L4B A;  2N6Z A;  5HVC A;  2K0Y A;  3GZM A;  1T8K A;  3LMO A;  2LOL A;  2N6Y A;  5EJD A;  2N5H A;  1HQB A;  2MD9 A;  2FVE A;  2CG5 B;  2LTE A;  2KOQ A;  4H2W C;  2FHS C;  2KWL A;  2KGC A;  1HY8 A;  2CGQ A;  1L0I A;  2KGD A;  2PNG A;  2AFE A;  2L22 A;  4H2X C;  2AFD A;  2KOS A;  3RG2 A;  2MY5 A;  2LPK A;  2EHT A;  2X2B A;  2LL8 A;  4CA3 A;  2L0Q A;  1KLP A;  4H2Y C;  2MF4 A;  1DNY A;  2XZ1 C;  2L9F A;  2FQ2 A;  4BPF A;  2MVV A;  4DG9 A;  2LKI A;  4PWV B;  2M5R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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