5HV8A

Solution structure of an octanoyl- loaded acyl carrier protein domain from module mlsa2 of the mycolactone polyketide synthase.
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
95
structure length
95
Chain Sequence
GSHMRLNGLSPQQQQQTLATLVAAATATVLGHHTPESISPATAFKDLGIDSLTALELRNTLTHNTGLDLPPTLIFDHPTPHALTQHLHTRLTQSH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Sticky swinging arm dynamics: studies of an acyl carrier protein domain from the mycolactone polyketide synthase.
pubmed doi rcsb
molecule tags Transferase
source organism Mycobacterium ulcerans
molecule keywords Type I modular polyketide synthase
total genus 26
structure length 95
sequence length 95
ec nomenclature
pdb deposition date 2016-01-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00550 PP-binding Phosphopantetheine attachment site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.10 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A ACP-like 5hv8A00
1L0IA 3GZMA 4H2XC 1NQ4A 2JU2A 3EJDA 5KP6B 1KLPA 2KGDA 2MVVA 2K93A 2KG8A 2JGPA 2KOSA 2FVFA 4CA3A 2EHTA 3RG2A 2X2BA 2CNRA 2MVUA 2XZ1C 4H2YC 2QNWA 2N5IA 2MD9A 3LMOA 2LOLA 2GDYA 2XZ0D 2MY5A 1ACPA 2MF4A 2LIWA 2N98A 2N5HA 2FQ0A 2LL8A 2EHSA 1L0HA 2CG5B 2KOQA 2FVEA 1OR5A 1T8KA 2FACA 2FAEA 4BPHA 5KP8B 2DNWA 2KGEA 2VSQA 3GZLA 4IZ6A 4NEOA 2KGAA 2LIUA 4MRTC 4BPGA 2FVAA 2AVAA 2KR5A 2L0QA 2N6YA 2KG6A 2LPKA 1HQBA 2KWLA 2FHSC 2L22A 2KGCA 4H2WC 2KORA 2L9FA 5CZDB 2LKIA 2K2QA 2KOPA 1DNYA 3EJEA 3NY7B 4HKGA 2MR7A 2LMLA 2K0YA 2N50A 2KW2A 2KG9A 2GDWA 1DV5A 4R0MA 2LTEA 2JU1A 2FQ1A 2FADA 1X3OA 2AFDA 2FQ2A 4PXHB 1VKUA 5HV8A 2AF8A 2K0XA 2CGQA 4BPFA 5HVCA 1F80D 2L4BA 2ROQA 2M5RA 2JQ4A 5KP7B 2CQ8A 2N6ZA 1HY8A 3EJBA 2GDXA 2MR8A 3CE7A 2PNGA 2AFEA 4PWVB 4DG9A 2KOOA 1AF8A 2K92A 5EJDA 2K94A
chains in the Genus database with same CATH superfamily
4H2XC 1NQ4A 2JU2A 1KLPA 2VLOA 3DS2A 1YJ9P 2GZJA 2JGPA 2KOSA 4CA3A 3CCUP 2XZ1C 4H2YC 2QNWA 2JBGA 2Z45A 3NTEA 2XZ0D 2XXMA 2EG5A 2MF4A 5BS2A 1VQ6P 3CCMP 2N5HA 2CG5B 2KOQA 1YJWP 3MGEA 5KP8B 1YITP 4XROA 4IZ6A 4NEOA 4GR2A 4MRTC 4BPGA 2AVAA 1M6EX 3CCQP 2KR5A 2L0QA 4U0AA 2PEIA 1EOQA 2ERHA 5HGMA 2KORA 2GZEA 3Q20A 1VQ7P 1N8RQ 2K2QA 4COCA 1DNYA 3EJEA 3NY7B 2MR7A 5JPAA 2CWOA 1DV5A 3G6EP 1MZ8A 2FQ1A 2GYKA 1M74A 1VQ4P 1X3OA 2AFDA 2FQ2A 4PXHB 1Q81Q 5F2NA 1IMPA 2AF8A 3HZQA 2K0XA 4BPFA 2M5RA 4IPYA 1GXGA 2KODA 2GDXA 2MR8A 3CE7A 2PNGA 3RG6C 3I55P 4DG9A 1Q82Q 1AF8A 3G1IA 3WBHA 5HGNA 5EJDA 3GZMA 3VRLC 1S72P 3GKLC 1AYIA 2MVVA 2K93A 2EHTA 2L6EA 1YIJP 3DS4A 5F2KA 2PENA 2N5IA 3LMOA 3H4EA 1VQKP 3E2DA 2GDYA 2PEOA 2N98A 1UNKA 3G4SP 1CEIA 4XFXA 1OR5A 1T8KA 1VQ9P 3HYBA 3GZLA 4XFZA 3DS5A 3CCRP 2KGAA 1NJIQ 1A43A 2QA4P 2VLPA 3CCJP 1HQBA 3CMEP 5DCKA 3M1MA 2KWLA 5CZDB 4H2WC 2L9FA 2PEQA 2KOPA 3OW2O 1E0HA 1VHNA 3LRYA 4U0BA 2KG9A 2GDWA 5HGLA 3CCVP 2M8LA 2JO0A 3B4QA 3G1GA 5HVCA 1QVGO 5KP7B 1KD1Q 2OTLP 2CQ8A 3CC7P 5BS1A 1M6NA 4WYMA 3H0DA 2PY8A 4PWVB 1YHQP 1K73Q 3CPWO 1FR2A 1EIAA 2K92A 2P9XA 5KP6B 1D1DA 2KGDA 1VQ8P 4U0EA 2KG8A 2JAZA 2CNRA 2LF4A 2K5XA 2K0DX 4COPA 1YI2P 2WPTA 1BAJA 3DS3A 2LOLA 2MY5A 2LIWA 2GZFA 2Z46A 2EHSA 3CC2P 3CC4P 4M0IA 5HGOA 2M8PA 7CEIA 2FAEA 3B5IA 2DGYA 2KGEA 3G26A 1KQSO 3CMAP 2LIUA 3DS0A 4F37A 2N6YA 2KG6A 2LPKA 4QNBA 1RNIA 2FHSC 2L22A 2KGCA 2Z44A 1K8AQ 2PEKA 3H47A 5I4TG 4HKGA 1RO0A 1JJ2O 1M1KQ 2N50A 2KW2A 3U43A 3G29A 4R0MA 2LTEA 2JYLA 2GZIA 2JU1A 2FADA 1AUMA 4XFYA 1VKUA 1VQ5P 1F80D 3DTJA 1GXHA 2L4BA 4PH1A 1VQPP 3CD6P 1HY8A 3EJBA 1EMVA 1VQOP 3G0VA 2AFEA 4UHPB 2OARA 2KOOA 2NO8A 4XRQA 4QKOA 2K94A 2XT1A 1L0IA 3EJDA 4U0CA 2XV6A 1UJZA 2FVFA 1K9MQ 1RO2A 3RG2A 2X2BA 2BUOA 2MVUA 1Q86Q 4U0FA 1A8OA 1M90Q 2MD9A 1VQMP 2OTJP 3G21A 1ACPA 2FQ0A 2QEXP 2LL8A 3CCEP 2VLNA 1L0HA 1QVFO 1QRJA 2FVEA 1VQLP 2FACA 3DPHA 4BPHA 2DNWA 2PEJA 2VSQA 3DS1A 1K30A 1E6JP 2FVAA 2JB0A 1KC8Q 3CCLP 2EFJA 3CXCO 1Q7YQ 3P05A 2BHVA 2LKIA 2GZGA 2E1MA 3G28A 2LMLA 2K0YA 2EIAA 3CCSP 2JYGA 1ZNVA 3I56P 1W2BO 5HV8A 1Z6MA 4GR6A 2CGQA 1ZMBA 1VQNP 2ROQA 1IMQA 2JQ4A 5F2OA 4PH0A 2M8NA 2VLQA 4U0DA 5EW5E 1GPJA 2N6ZA 1BXIA 2ONTA 2PEMA 1YJNP 1IUQA 3GJNA 3G71P
chains in the Genus database with same CATH topology
1L0IA 3GZMA 4H2XC 1NQ4A 2JU2A 3EJDA 5KP6B 1KLPA 2KGDA 2MVVA 2K93A 2KG8A 2JGPA 2KOSA 2FVFA 4CA3A 2EHTA 3RG2A 2X2BA 2CNRA 2MVUA 2XZ1C 4H2YC 2QNWA 2N5IA 2MD9A 3LMOA 2LOLA 2GDYA 2XZ0D 2MY5A 1ACPA 2MF4A 2LIWA 2N98A 2N5HA 2FQ0A 2LL8A 2EHSA 1L0HA 2CG5B 2KOQA 2FVEA 1OR5A 1T8KA 2FACA 2FAEA 4BPHA 5KP8B 2DNWA 2KGEA 2VSQA 3GZLA 4IZ6A 4NEOA 2KGAA 2LIUA 4MRTC 4BPGA 2FVAA 2AVAA 2KR5A 2L0QA 2N6YA 2KG6A 2LPKA 1HQBA 2KWLA 2FHSC 2L22A 2KGCA 4H2WC 2KORA 2L9FA 5CZDB 2LKIA 2K2QA 2KOPA 1DNYA 3EJEA 3NY7B 4HKGA 2MR7A 2LMLA 2K0YA 2N50A 2KW2A 2KG9A 2GDWA 1DV5A 4R0MA 2LTEA 2JU1A 2FQ1A 2FADA 1X3OA 2AFDA 2FQ2A 4PXHB 1VKUA 5HV8A 2AF8A 2K0XA 2CGQA 4BPFA 5HVCA 1F80D 2L4BA 2ROQA 2M5RA 2JQ4A 5KP7B 2CQ8A 2N6ZA 1HY8A 3EJBA 2GDXA 2MR8A 3CE7A 2PNGA 2AFEA 4PWVB 4DG9A 2KOOA 1AF8A 2K92A 5EJDA 2K94A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1L0I A;  3GZM A;  4H2X C;  1NQ4 A;  2JU2 A;  3EJD A;  5KP6 B;  1KLP A;  2KGD A;  2MVV A;  2K93 A;  2KG8 A;  2JGP A;  2KOS A;  2FVF A;  4CA3 A;  2EHT A;  3RG2 A;  2X2B A;  2CNR A;  2MVU A;  2XZ1 C;  4H2Y C;  2QNW A;  2N5I A;  2MD9 A;  3LMO A;  2LOL A;  2GDY A;  2XZ0 D;  2MY5 A;  1ACP A;  2MF4 A;  2LIW A;  2N98 A;  2N5H A;  2FQ0 A;  2LL8 A;  2EHS A;  1L0H A;  2CG5 B;  2KOQ A;  2FVE A;  1OR5 A;  1T8K A;  2FAC A;  2FAE A;  4BPH A;  5KP8 B;  2DNW A;  2KGE A;  2VSQ A;  3GZL A;  4IZ6 A;  4NEO A;  2KGA A;  2LIU A;  4MRT C;  4BPG A;  2FVA A;  2AVA A;  2KR5 A;  2L0Q A;  2N6Y A;  2KG6 A;  2LPK A;  1HQB A;  2KWL A;  2FHS C;  2L22 A;  2KGC A;  4H2W C;  2KOR A;  2L9F A;  5CZD B;  2LKI A;  2K2Q A;  2KOP A;  1DNY A;  3EJE A;  3NY7 B;  4HKG A;  2MR7 A;  2LML A;  2K0Y A;  2N50 A;  2KW2 A;  2KG9 A;  2GDW A;  1DV5 A;  4R0M A;  2LTE A;  2JU1 A;  2FQ1 A;  2FAD A;  1X3O A;  2AFD A;  2FQ2 A;  4PXH B;  1VKU A;  5HV8 A;  2AF8 A;  2K0X A;  2CGQ A;  4BPF A;  5HVC A;  1F80 D;  2L4B A;  2ROQ A;  2M5R A;  2JQ4 A;  5KP7 B;  2CQ8 A;  2N6Z A;  1HY8 A;  3EJB A;  2GDX A;  2MR8 A;  3CE7 A;  2PNG A;  2AFE A;  4PWV B;  4DG9 A;  2KOO A;  1AF8 A;  2K92 A;  5EJD A;  2K94 A; 
#chains in the Genus database with same CATH topology
 4H2X C;  1NQ4 A;  2JU2 A;  1KLP A;  2VLO A;  3DS2 A;  1YJ9 P;  2GZJ A;  2JGP A;  2KOS A;  4CA3 A;  3CCU P;  2XZ1 C;  4H2Y C;  2QNW A;  2JBG A;  2Z45 A;  3NTE A;  2XZ0 D;  2XXM A;  2EG5 A;  2MF4 A;  5BS2 A;  1VQ6 P;  3CCM P;  2N5H A;  2CG5 B;  2KOQ A;  1YJW P;  3MGE A;  5KP8 B;  1YIT P;  4XRO A;  4IZ6 A;  4NEO A;  4GR2 A;  4MRT C;  4BPG A;  2AVA A;  1M6E X;  3CCQ P;  2KR5 A;  2L0Q A;  4U0A A;  2PEI A;  1EOQ A;  2ERH A;  5HGM A;  2KOR A;  2GZE A;  3Q20 A;  1VQ7 P;  1N8R Q;  2K2Q A;  4COC A;  1DNY A;  3EJE A;  3NY7 B;  2MR7 A;  5JPA A;  2CWO A;  1DV5 A;  3G6E P;  1MZ8 A;  2FQ1 A;  2GYK A;  1M74 A;  1VQ4 P;  1X3O A;  2AFD A;  2FQ2 A;  4PXH B;  1Q81 Q;  5F2N A;  1IMP A;  2AF8 A;  3HZQ A;  2K0X A;  4BPF A;  2M5R A;  4IPY A;  1GXG A;  2KOD A;  2GDX A;  2MR8 A;  3CE7 A;  2PNG A;  3RG6 C;  3I55 P;  4DG9 A;  1Q82 Q;  1AF8 A;  3G1I A;  3WBH A;  5HGN A;  5EJD A;  3GZM A;  3VRL C;  1S72 P;  3GKL C;  1AYI A;  2MVV A;  2K93 A;  2EHT A;  2L6E A;  1YIJ P;  3DS4 A;  5F2K A;  2PEN A;  2N5I A;  3LMO A;  3H4E A;  1VQK P;  3E2D A;  2GDY A;  2PEO A;  2N98 A;  1UNK A;  3G4S P;  1CEI A;  4XFX A;  1OR5 A;  1T8K A;  1VQ9 P;  3HYB A;  3GZL A;  4XFZ A;  3DS5 A;  3CCR P;  2KGA A;  1NJI Q;  1A43 A;  2QA4 P;  2VLP A;  3CCJ P;  1HQB A;  3CME P;  5DCK A;  3M1M A;  2KWL A;  5CZD B;  4H2W C;  2L9F A;  2PEQ A;  2KOP A;  3OW2 O;  1E0H A;  1VHN A;  3LRY A;  4U0B A;  2KG9 A;  2GDW A;  5HGL A;  3CCV P;  2M8L A;  2JO0 A;  3B4Q A;  3G1G A;  5HVC A;  1QVG O;  5KP7 B;  1KD1 Q;  2OTL P;  2CQ8 A;  3CC7 P;  5BS1 A;  1M6N A;  4WYM A;  3H0D A;  2PY8 A;  4PWV B;  1YHQ P;  1K73 Q;  3CPW O;  1FR2 A;  1EIA A;  2K92 A;  2P9X A;  5KP6 B;  1D1D A;  2KGD A;  1VQ8 P;  4U0E A;  2KG8 A;  2JAZ A;  2CNR A;  2LF4 A;  2K5X A;  2K0D X;  4COP A;  1YI2 P;  2WPT A;  1BAJ A;  3DS3 A;  2LOL A;  2MY5 A;  2LIW A;  2GZF A;  2Z46 A;  2EHS A;  3CC2 P;  3CC4 P;  4M0I A;  5HGO A;  2M8P A;  7CEI A;  2FAE A;  3B5I A;  2DGY A;  2KGE A;  3G26 A;  1KQS O;  3CMA P;  2LIU A;  3DS0 A;  4F37 A;  2N6Y A;  2KG6 A;  2LPK A;  4QNB A;  1RNI A;  2FHS C;  2L22 A;  2KGC A;  2Z44 A;  1K8A Q;  2PEK A;  3H47 A;  5I4T G;  4HKG A;  1RO0 A;  1JJ2 O;  1M1K Q;  2N50 A;  2KW2 A;  3U43 A;  3G29 A;  4R0M A;  2LTE A;  2JYL A;  2GZI A;  2JU1 A;  2FAD A;  1AUM A;  4XFY A;  1VKU A;  1VQ5 P;  1F80 D;  3DTJ A;  1GXH A;  2L4B A;  4PH1 A;  1VQP P;  3CD6 P;  1HY8 A;  3EJB A;  1EMV A;  1VQO P;  3G0V A;  2AFE A;  4UHP B;  2OAR A;  2KOO A;  2NO8 A;  4XRQ A;  4QKO A;  2K94 A;  2XT1 A;  1L0I A;  3EJD A;  4U0C A;  2XV6 A;  1UJZ A;  2FVF A;  1K9M Q;  1RO2 A;  3RG2 A;  2X2B A;  2BUO A;  2MVU A;  1Q86 Q;  4U0F A;  1A8O A;  1M90 Q;  2MD9 A;  1VQM P;  2OTJ P;  3G21 A;  1ACP A;  2FQ0 A;  2QEX P;  2LL8 A;  3CCE P;  2VLN A;  1L0H A;  1QVF O;  1QRJ A;  2FVE A;  1VQL P;  2FAC A;  3DPH A;  4BPH A;  2DNW A;  2PEJ A;  2VSQ A;  3DS1 A;  1K30 A;  1E6J P;  2FVA A;  2JB0 A;  1KC8 Q;  3CCL P;  2EFJ A;  3CXC O;  1Q7Y Q;  3P05 A;  2BHV A;  2LKI A;  2GZG A;  2E1M A;  3G28 A;  2LML A;  2K0Y A;  2EIA A;  3CCS P;  2JYG A;  1ZNV A;  3I56 P;  1W2B O;  5HV8 A;  1Z6M A;  4GR6 A;  2CGQ A;  1ZMB A;  1VQN P;  2ROQ A;  1IMQ A;  2JQ4 A;  5F2O A;  4PH0 A;  2M8N A;  2VLQ A;  4U0D A;  5EW5 E;  1GPJ A;  2N6Z A;  1BXI A;  2ONT A;  2PEM A;  1YJN P;  1IUQ A;  3GJN A;  3G71 P; 
#chains in the Genus database with same CATH homology
 1L0I A;  3GZM A;  4H2X C;  1NQ4 A;  2JU2 A;  3EJD A;  5KP6 B;  1KLP A;  2KGD A;  2MVV A;  2K93 A;  2KG8 A;  2JGP A;  2KOS A;  2FVF A;  4CA3 A;  2EHT A;  3RG2 A;  2X2B A;  2CNR A;  2MVU A;  2XZ1 C;  4H2Y C;  2QNW A;  2N5I A;  2MD9 A;  3LMO A;  2LOL A;  2GDY A;  2XZ0 D;  2MY5 A;  1ACP A;  2MF4 A;  2LIW A;  2N98 A;  2N5H A;  2FQ0 A;  2LL8 A;  2EHS A;  1L0H A;  2CG5 B;  2KOQ A;  2FVE A;  1OR5 A;  1T8K A;  2FAC A;  2FAE A;  4BPH A;  5KP8 B;  2DNW A;  2KGE A;  2VSQ A;  3GZL A;  4IZ6 A;  4NEO A;  2KGA A;  2LIU A;  4MRT C;  4BPG A;  2FVA A;  2AVA A;  2KR5 A;  2L0Q A;  2N6Y A;  2KG6 A;  2LPK A;  1HQB A;  2KWL A;  2FHS C;  2L22 A;  2KGC A;  4H2W C;  2KOR A;  2L9F A;  5CZD B;  2LKI A;  2K2Q A;  2KOP A;  1DNY A;  3EJE A;  3NY7 B;  4HKG A;  2MR7 A;  2LML A;  2K0Y A;  2N50 A;  2KW2 A;  2KG9 A;  2GDW A;  1DV5 A;  4R0M A;  2LTE A;  2JU1 A;  2FQ1 A;  2FAD A;  1X3O A;  2AFD A;  2FQ2 A;  4PXH B;  1VKU A;  5HV8 A;  2AF8 A;  2K0X A;  2CGQ A;  4BPF A;  5HVC A;  1F80 D;  2L4B A;  2ROQ A;  2M5R A;  2JQ4 A;  5KP7 B;  2CQ8 A;  2N6Z A;  1HY8 A;  3EJB A;  2GDX A;  2MR8 A;  3CE7 A;  2PNG A;  2AFE A;  4PWV B;  4DG9 A;  2KOO A;  1AF8 A;  2K92 A;  5EJD A;  2K94 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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