5KP7B

Crystal structure of the curacin biosynthetic pathway hmg synthase in complex with holo donor-acp
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
79
structure length
79
Chain Sequence
MSKEQVLKIIKKYTREIAPELEDSPLEPTDSLKKLGIDSVNRAEIIMMVMEDLSLNIPRIELAGAKNIGELADLFAAKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Anatomy of the beta-branching enzyme of polyketide biosynthesis and its interaction with an acyl-ACP substrate.
pubmed doi rcsb
molecule tags Transferase
source organism Moorea producens 3l
molecule keywords CurD
total genus 25
structure length 79
sequence length 79
ec nomenclature
pdb deposition date 2016-07-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00550 PP-binding Phosphopantetheine attachment site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.10 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A ACP-like 5kp7B00
2K92A 2LL8A 5HV8A 2N6YA 2MY5A 5CZDB 2FVEA 5KP8B 2FACA 1L0IA 3GZLA 2LIWA 2LPKA 2AFDA 2L22A 2N6ZA 2VSQA 2AF8A 4DG9A 1DV5A 2KWLA 2QNWA 3NY7B 4PWVB 2KGCA 1NQ4A 3LMOA 2FHSC 2KOQA 3RG2A 1L0HA 2FVFA 2K2QA 4MRTC 4H2WC 2EHTA 2FQ2A 4IZ6A 2K0XA 2JU2A 2MR8A 2M5RA 2N98A 2CGQA 4PXHB 2LKIA 2CNRA 2MVUA 2KG6A 1AF8A 2JQ4A 2KOPA 5KP7B 2K94A 3EJBA 2KORA 2L0QA 2FQ0A 2X2BA 2MVVA 5HVCA 2GDXA 4H2YC 1KLPA 2KG8A 4R0MA 2AFEA 2FADA 2KG9A 2K93A 2DNWA 3CE7A 2KGEA 2LTEA 2MF4A 2N50A 1X3OA 2KOOA 2KW2A 5EJDA 1DNYA 2JU1A 1F80D 2LIUA 2ROQA 4BPFA 1HQBA 1VKUA 1HY8A 4BPGA 2JGPA 2KR5A 2N5HA 3EJEA 1ACPA 2KGDA 3EJDA 5KP6B 2FVAA 2LMLA 2CG5B 2FQ1A 2XZ0D 2MD9A 2MR7A 4H2XC 2GDWA 3GZMA 2AVAA 2KOSA 2L4BA 2N5IA 2K0YA 4NEOA 2LOLA 4BPHA 1OR5A 2GDYA 2KGAA 2L9FA 4CA3A 4HKGA 2FAEA 1T8KA 2XZ1C 2PNGA 2EHSA 2CQ8A
chains in the Genus database with same CATH superfamily
2LL8A 2GZIA 1VQ8P 3CCRP 2GZFA 2JBGA 2PEKA 2AFDA 1VQPP 3M1MA 3CCQP 2JAZA 4DG9A 3CD6P 4XFXA 2FHSC 3MGEA 1RO2A 4U0CA 3CXCO 5DCKA 1Q7YQ 2JO0A 2MVUA 1JJ2O 3VRLC 2KG6A 2KOPA 2Z44A 2K94A 2NO8A 2M8LA 2FQ0A 3I56P 1Q81Q 1KLPA 2PEQA 2KG8A 1RNIA 2GZJA 3CE7A 2LTEA 1K9MQ 2MF4A 2ONTA 3GJNA 1YJWP 3B4QA 4COCA 1Q82Q 5F2NA 1YHQP 3G26A 3G71P 1F80D 1EOQA 1EMVA 1QVGO 1HY8A 1QRJA 2JYGA 2PY8A 2KR5A 2N5HA 3CCMP 1VQMP 1YITP 3RG6C 4XROA 2KGDA 3DTJA 3EJDA 2FVAA 2CG5B 1YIJP 3LRYA 2MR7A 3CCLP 5F2KA 7CEIA 1D1DA 1S72P 2K0DX 2LOLA 3CC2P 3G1GA 1M6NA 2EFJA 1M6EX 4IPYA 2XZ1C 2K5XA 2CQ8A 2N6YA 1VQ6P 2FVEA 1YI2P 3GZLA 2L22A 1YJNP 2AF8A 1M90Q 1DV5A 2KWLA 1NQ4A 5F2OA 3RG2A 3G21A 5HGNA 2L6EA 5HGMA 2K2QA 2DGYA 1NJIQ 2EHTA 3CMEP 2M8NA 3U43A 1W2BO 2MR8A 2M5RA 2N98A 3HZQA 2E1MA 1Z6MA 2LKIA 2CNRA 5KP7B 2L0QA 1VQ7P 3WBHA 4U0FA 2X2BA 2KODA 3OW2O 3DS5A 2AFEA 1KD1Q 2FADA 2K93A 4WYMA 3G29A 1M74A 3CPWO 2N50A 1VQLP 3CCVP 2KW2A 2PEMA 1DNYA 2GYKA 2GZEA 2VLQA 1E6JP 1A43A 2CWOA 1GPJA 1ACPA 2XT1A 2LMLA 4XFYA 4PH1A 3GZMA 2L4BA 2KOSA 2N5IA 1EIAA 2PEJA 1KC8Q 1FR2A 2OTLP 3CCJP 4CA3A 4HKGA 2FAEA 2BUOA 1A8OA 2PEOA 3B5IA 5HV8A 2MY5A 2EG5A 5CZDB 2VLPA 2FACA 1L0IA 2OARA 2LIWA 2N6ZA 1UJZA 2WPTA 2VSQA 2XV6A 2QNWA 3NY7B 4PWVB 2JB0A 1K8AQ 1K30A 3G6EP 2FVFA 1VQOP 4QKOA 4H2WC 3DPHA 3CCSP 4PXHB 2QEXP 1GXHA 3CC7P 1QVFO 3EJBA 2JYLA 2KORA 5BS1A 4U0AA 3G1IA 5I4TG 1CEIA 5HVCA 4UHPB 2GDXA 4H2YC 3CCUP 4M0IA 3Q20A 3NTEA 2VLNA 1N8RQ 2BHVA 1KQSO 1M1KQ 3H47A 2ROQA 4BPFA 4BPGA 3EJEA 4U0DA 5KP6B 1AUMA 2FQ1A 2XZ0D 2PEIA 3DS2A 5JPAA 2OTJP 1AYIA 3DS1A 1UNKA 4NEOA 4BPHA 1OR5A 2L9FA 2LF4A 1K73Q 3G0VA 3P05A 4PH0A 4QNBA 5BS2A 2EHSA 2K92A 1IMQA 5HGLA 5KP8B 2P9XA 2LPKA 1VQ5P 1VQ4P 3G28A 2KGCA 3DS4A 3LMOA 1E0HA 2KOQA 1L0HA 5EW5E 3I55P 4MRTC 1MZ8A 1VQNP 2QA4P 4U0EA 2FQ2A 4IZ6A 4XRQA 2K0XA 2JU2A 2Z45A 2CGQA 2ERHA 2GZGA 1AF8A 2JQ4A 1IMPA 3CCEP 4F37A 2MVVA 1YJ9P 3DS3A 3CMAP 4R0MA 2M8PA 2KG9A 2DNWA 3HYBA 1IUQA 3GKLC 2KGEA 1Q86Q 5HGOA 3H0DA 3CC4P 2EIAA 2VLOA 1X3OA 2KOOA 5EJDA 1VQ9P 2JU1A 2LIUA 4XFZA 3H4EA 2Z46A 1HQBA 1VKUA 2PENA 2JGPA 1BAJA 3G4SP 3DS0A 2XXMA 3E2DA 4COPA 4GR2A 1VQKP 2MD9A 4H2XC 1ZMBA 1RO0A 2AVAA 1GXGA 2GDWA 2K0YA 2KGAA 2GDYA 4GR6A 1ZNVA 1T8KA 1BXIA 4U0BA 2PNGA 1VHNA
chains in the Genus database with same CATH topology
2K92A 2LL8A 5HV8A 2N6YA 2MY5A 5CZDB 2FVEA 5KP8B 2FACA 1L0IA 3GZLA 2LIWA 2LPKA 2AFDA 2L22A 2N6ZA 2VSQA 2AF8A 4DG9A 1DV5A 2KWLA 2QNWA 3NY7B 4PWVB 2KGCA 1NQ4A 3LMOA 2FHSC 2KOQA 3RG2A 1L0HA 2FVFA 2K2QA 4MRTC 4H2WC 2EHTA 2FQ2A 4IZ6A 2K0XA 2JU2A 2MR8A 2M5RA 2N98A 2CGQA 4PXHB 2LKIA 2CNRA 2MVUA 2KG6A 1AF8A 2JQ4A 2KOPA 5KP7B 2K94A 3EJBA 2KORA 2L0QA 2FQ0A 2X2BA 2MVVA 5HVCA 2GDXA 4H2YC 1KLPA 2KG8A 4R0MA 2AFEA 2FADA 2KG9A 2K93A 2DNWA 3CE7A 2KGEA 2LTEA 2MF4A 2N50A 1X3OA 2KOOA 2KW2A 5EJDA 1DNYA 2JU1A 1F80D 2LIUA 2ROQA 4BPFA 1HQBA 1VKUA 1HY8A 4BPGA 2JGPA 2KR5A 2N5HA 3EJEA 1ACPA 2KGDA 3EJDA 5KP6B 2FVAA 2LMLA 2CG5B 2FQ1A 2XZ0D 2MD9A 2MR7A 4H2XC 2GDWA 3GZMA 2AVAA 2KOSA 2L4BA 2N5IA 2K0YA 4NEOA 2LOLA 4BPHA 1OR5A 2GDYA 2KGAA 2L9FA 4CA3A 4HKGA 2FAEA 1T8KA 2XZ1C 2PNGA 2EHSA 2CQ8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2K92 A;  2LL8 A;  5HV8 A;  2N6Y A;  2MY5 A;  5CZD B;  2FVE A;  5KP8 B;  2FAC A;  1L0I A;  3GZL A;  2LIW A;  2LPK A;  2AFD A;  2L22 A;  2N6Z A;  2VSQ A;  2AF8 A;  4DG9 A;  1DV5 A;  2KWL A;  2QNW A;  3NY7 B;  4PWV B;  2KGC A;  1NQ4 A;  3LMO A;  2FHS C;  2KOQ A;  3RG2 A;  1L0H A;  2FVF A;  2K2Q A;  4MRT C;  4H2W C;  2EHT A;  2FQ2 A;  4IZ6 A;  2K0X A;  2JU2 A;  2MR8 A;  2M5R A;  2N98 A;  2CGQ A;  4PXH B;  2LKI A;  2CNR A;  2MVU A;  2KG6 A;  1AF8 A;  2JQ4 A;  2KOP A;  5KP7 B;  2K94 A;  3EJB A;  2KOR A;  2L0Q A;  2FQ0 A;  2X2B A;  2MVV A;  5HVC A;  2GDX A;  4H2Y C;  1KLP A;  2KG8 A;  4R0M A;  2AFE A;  2FAD A;  2KG9 A;  2K93 A;  2DNW A;  3CE7 A;  2KGE A;  2LTE A;  2MF4 A;  2N50 A;  1X3O A;  2KOO A;  2KW2 A;  5EJD A;  1DNY A;  2JU1 A;  1F80 D;  2LIU A;  2ROQ A;  4BPF A;  1HQB A;  1VKU A;  1HY8 A;  4BPG A;  2JGP A;  2KR5 A;  2N5H A;  3EJE A;  1ACP A;  2KGD A;  3EJD A;  5KP6 B;  2FVA A;  2LML A;  2CG5 B;  2FQ1 A;  2XZ0 D;  2MD9 A;  2MR7 A;  4H2X C;  2GDW A;  3GZM A;  2AVA A;  2KOS A;  2L4B A;  2N5I A;  2K0Y A;  4NEO A;  2LOL A;  4BPH A;  1OR5 A;  2GDY A;  2KGA A;  2L9F A;  4CA3 A;  4HKG A;  2FAE A;  1T8K A;  2XZ1 C;  2PNG A;  2EHS A;  2CQ8 A; 
#chains in the Genus database with same CATH topology
 2LL8 A;  2GZI A;  1VQ8 P;  3CCR P;  2GZF A;  2JBG A;  2PEK A;  2AFD A;  1VQP P;  3M1M A;  3CCQ P;  2JAZ A;  4DG9 A;  3CD6 P;  4XFX A;  2FHS C;  3MGE A;  1RO2 A;  4U0C A;  3CXC O;  5DCK A;  1Q7Y Q;  2JO0 A;  2MVU A;  1JJ2 O;  3VRL C;  2KG6 A;  2KOP A;  2Z44 A;  2K94 A;  2NO8 A;  2M8L A;  2FQ0 A;  3I56 P;  1Q81 Q;  1KLP A;  2PEQ A;  2KG8 A;  1RNI A;  2GZJ A;  3CE7 A;  2LTE A;  1K9M Q;  2MF4 A;  2ONT A;  3GJN A;  1YJW P;  3B4Q A;  4COC A;  1Q82 Q;  5F2N A;  1YHQ P;  3G26 A;  3G71 P;  1F80 D;  1EOQ A;  1EMV A;  1QVG O;  1HY8 A;  1QRJ A;  2JYG A;  2PY8 A;  2KR5 A;  2N5H A;  3CCM P;  1VQM P;  1YIT P;  3RG6 C;  4XRO A;  2KGD A;  3DTJ A;  3EJD A;  2FVA A;  2CG5 B;  1YIJ P;  3LRY A;  2MR7 A;  3CCL P;  5F2K A;  7CEI A;  1D1D A;  1S72 P;  2K0D X;  2LOL A;  3CC2 P;  3G1G A;  1M6N A;  2EFJ A;  1M6E X;  4IPY A;  2XZ1 C;  2K5X A;  2CQ8 A;  2N6Y A;  1VQ6 P;  2FVE A;  1YI2 P;  3GZL A;  2L22 A;  1YJN P;  2AF8 A;  1M90 Q;  1DV5 A;  2KWL A;  1NQ4 A;  5F2O A;  3RG2 A;  3G21 A;  5HGN A;  2L6E A;  5HGM A;  2K2Q A;  2DGY A;  1NJI Q;  2EHT A;  3CME P;  2M8N A;  3U43 A;  1W2B O;  2MR8 A;  2M5R A;  2N98 A;  3HZQ A;  2E1M A;  1Z6M A;  2LKI A;  2CNR A;  5KP7 B;  2L0Q A;  1VQ7 P;  3WBH A;  4U0F A;  2X2B A;  2KOD A;  3OW2 O;  3DS5 A;  2AFE A;  1KD1 Q;  2FAD A;  2K93 A;  4WYM A;  3G29 A;  1M74 A;  3CPW O;  2N50 A;  1VQL P;  3CCV P;  2KW2 A;  2PEM A;  1DNY A;  2GYK A;  2GZE A;  2VLQ A;  1E6J P;  1A43 A;  2CWO A;  1GPJ A;  1ACP A;  2XT1 A;  2LML A;  4XFY A;  4PH1 A;  3GZM A;  2L4B A;  2KOS A;  2N5I A;  1EIA A;  2PEJ A;  1KC8 Q;  1FR2 A;  2OTL P;  3CCJ P;  4CA3 A;  4HKG A;  2FAE A;  2BUO A;  1A8O A;  2PEO A;  3B5I A;  5HV8 A;  2MY5 A;  2EG5 A;  5CZD B;  2VLP A;  2FAC A;  1L0I A;  2OAR A;  2LIW A;  2N6Z A;  1UJZ A;  2WPT A;  2VSQ A;  2XV6 A;  2QNW A;  3NY7 B;  4PWV B;  2JB0 A;  1K8A Q;  1K30 A;  3G6E P;  2FVF A;  1VQO P;  4QKO A;  4H2W C;  3DPH A;  3CCS P;  4PXH B;  2QEX P;  1GXH A;  3CC7 P;  1QVF O;  3EJB A;  2JYL A;  2KOR A;  5BS1 A;  4U0A A;  3G1I A;  5I4T G;  1CEI A;  5HVC A;  4UHP B;  2GDX A;  4H2Y C;  3CCU P;  4M0I A;  3Q20 A;  3NTE A;  2VLN A;  1N8R Q;  2BHV A;  1KQS O;  1M1K Q;  3H47 A;  2ROQ A;  4BPF A;  4BPG A;  3EJE A;  4U0D A;  5KP6 B;  1AUM A;  2FQ1 A;  2XZ0 D;  2PEI A;  3DS2 A;  5JPA A;  2OTJ P;  1AYI A;  3DS1 A;  1UNK A;  4NEO A;  4BPH A;  1OR5 A;  2L9F A;  2LF4 A;  1K73 Q;  3G0V A;  3P05 A;  4PH0 A;  4QNB A;  5BS2 A;  2EHS A;  2K92 A;  1IMQ A;  5HGL A;  5KP8 B;  2P9X A;  2LPK A;  1VQ5 P;  1VQ4 P;  3G28 A;  2KGC A;  3DS4 A;  3LMO A;  1E0H A;  2KOQ A;  1L0H A;  5EW5 E;  3I55 P;  4MRT C;  1MZ8 A;  1VQN P;  2QA4 P;  4U0E A;  2FQ2 A;  4IZ6 A;  4XRQ A;  2K0X A;  2JU2 A;  2Z45 A;  2CGQ A;  2ERH A;  2GZG A;  1AF8 A;  2JQ4 A;  1IMP A;  3CCE P;  4F37 A;  2MVV A;  1YJ9 P;  3DS3 A;  3CMA P;  4R0M A;  2M8P A;  2KG9 A;  2DNW A;  3HYB A;  1IUQ A;  3GKL C;  2KGE A;  1Q86 Q;  5HGO A;  3H0D A;  3CC4 P;  2EIA A;  2VLO A;  1X3O A;  2KOO A;  5EJD A;  1VQ9 P;  2JU1 A;  2LIU A;  4XFZ A;  3H4E A;  2Z46 A;  1HQB A;  1VKU A;  2PEN A;  2JGP A;  1BAJ A;  3G4S P;  3DS0 A;  2XXM A;  3E2D A;  4COP A;  4GR2 A;  1VQK P;  2MD9 A;  4H2X C;  1ZMB A;  1RO0 A;  2AVA A;  1GXG A;  2GDW A;  2K0Y A;  2KGA A;  2GDY A;  4GR6 A;  1ZNV A;  1T8K A;  1BXI A;  4U0B A;  2PNG A;  1VHN A; 
#chains in the Genus database with same CATH homology
 2K92 A;  2LL8 A;  5HV8 A;  2N6Y A;  2MY5 A;  5CZD B;  2FVE A;  5KP8 B;  2FAC A;  1L0I A;  3GZL A;  2LIW A;  2LPK A;  2AFD A;  2L22 A;  2N6Z A;  2VSQ A;  2AF8 A;  4DG9 A;  1DV5 A;  2KWL A;  2QNW A;  3NY7 B;  4PWV B;  2KGC A;  1NQ4 A;  3LMO A;  2FHS C;  2KOQ A;  3RG2 A;  1L0H A;  2FVF A;  2K2Q A;  4MRT C;  4H2W C;  2EHT A;  2FQ2 A;  4IZ6 A;  2K0X A;  2JU2 A;  2MR8 A;  2M5R A;  2N98 A;  2CGQ A;  4PXH B;  2LKI A;  2CNR A;  2MVU A;  2KG6 A;  1AF8 A;  2JQ4 A;  2KOP A;  5KP7 B;  2K94 A;  3EJB A;  2KOR A;  2L0Q A;  2FQ0 A;  2X2B A;  2MVV A;  5HVC A;  2GDX A;  4H2Y C;  1KLP A;  2KG8 A;  4R0M A;  2AFE A;  2FAD A;  2KG9 A;  2K93 A;  2DNW A;  3CE7 A;  2KGE A;  2LTE A;  2MF4 A;  2N50 A;  1X3O A;  2KOO A;  2KW2 A;  5EJD A;  1DNY A;  2JU1 A;  1F80 D;  2LIU A;  2ROQ A;  4BPF A;  1HQB A;  1VKU A;  1HY8 A;  4BPG A;  2JGP A;  2KR5 A;  2N5H A;  3EJE A;  1ACP A;  2KGD A;  3EJD A;  5KP6 B;  2FVA A;  2LML A;  2CG5 B;  2FQ1 A;  2XZ0 D;  2MD9 A;  2MR7 A;  4H2X C;  2GDW A;  3GZM A;  2AVA A;  2KOS A;  2L4B A;  2N5I A;  2K0Y A;  4NEO A;  2LOL A;  4BPH A;  1OR5 A;  2GDY A;  2KGA A;  2L9F A;  4CA3 A;  4HKG A;  2FAE A;  1T8K A;  2XZ1 C;  2PNG A;  2EHS A;  2CQ8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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