3CXCO

The structure of an enhanced oxazolidinone inhibitor bound to the 50s ribosomal subunit of h. marismortui
Total Genus 50
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
143
structure length
143
Chain Sequence
TDLSAQKRLAADVLDVGKNRVWFNPERQGDIADAITREDVRELVDEGAIQAKDKKGNSRGRARERQKKRAKGHQKGAGSRKGKAGARQNSKEDWESRIRAQRTKLRELRDEGTLSSSQYRDLYDKAGGGEFDSVADLERYIDA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Design at the atomic level: design of biaryloxazolidinones as potent orally active antibiotics.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S RIBOSOMAL RNA
total genus 50
structure length 143
sequence length 143
ec nomenclature
pdb deposition date 2008-04-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
O PF01280 Ribosomal_L19e Ribosomal protein L19e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.60 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A 3cxcO02
1.10.1650.10 Mainly Alpha Orthogonal Bundle 50s Ribosomal Protein L19e, Chain O, domain 1 50s Ribosomal Protein L19e, Chain O, domain 1 3cxcO01
1JJ2O 1YJNP 3CCQP 3OW2O 1Q86Q 1K73Q 1YIJP 3CPWO 1Q82Q 1M1KQ 1QVFO 3CCJP 1YJWP 1NJIQ 3I55P 1KD1Q 1VQNP 1VQ6P 3CMAP 1QVGO 1W2BO 1VQMP 3CCUP 1YJ9P 1M90Q 3CC2P 3CCLP 1KC8Q 1Q7YQ 1VQ9P 3I56P 3CCVP 3CXCO 2OTJP 1KQSO 3CC4P 1VQPP 1VQ7P 1K9MQ 1VQ4P 2QEXP 1VQ5P 3G71P 1K8AQ 3CC7P 2OTLP 3CD6P 1VQKP 1YI2P 1S72P 1VQ8P 3G4SP 1N8RQ 1VQLP 3CCEP 2QA4P 1VQOP 3CMEP 1Q81Q 1YHQP 1YITP 3CCRP 3CCSP 3G6EP 3CCMP
chains in the Genus database with same CATH superfamily
1BAJA 1M1KQ 3GJNA 2JAZA 1VHNA 2LPKA 1VQNP 2ONTA 2K93A 1F80D 1ZNVA 1ZMBA 2PEMA 1L0IA 2EHSA 4PWVB 5BS1A 1K30A 3CXCO 5CZDB 2N50A 2M8PA 2CGQA 4COCA 4QKOA 4PXHB 2FHSC 1T8KA 2CG5B 7CEIA 2KG9A 4WYMA 2JYLA 2GZEA 2N6ZA 1RO2A 1BXIA 5BS2A 1PEQA 1M6NA 3CCUP 1CEIA 3P05A 1RNIA 2QNWA 4GR2A 1E6JP 2Z46A 1Z6MA 2M5RA 2JB0A 2MY5A 1YJ9P 2Z45A 2JBGA 5EW5E 1DNYA 2MR8A 5I4TG 2PEOA 4R0MA 3EJEA 2X2BA 2OTJP 3DS4A 4U0CA 1VQKP 2GZFA 2KOSA 4F37A 1A43A 4XFYA 1YHQP 2AFEA 2KODA 4BPHA 3G6EP 2K5XA 3EJDA 2P9XA 5F2OA 3LMOA 2K0YA 2EIAA 2GZGA 1QVGO 1VQMP 2MVVA 1D1DA 2FQ2A 1AUMA 5HVCA 1L0HA 1VQ5P 2FVAA 1M6EX 1EMVA 3MGEA 2BQ1E 3CCEP 2LKIA 3WBHA 2KOPA 1DV5A 3CCSP 3G29A 3CCMP 2N5HA 1YIJP 3NTEA 1KD1Q 2NO8A 2JGPA 1IUQA 2EFJA 4DG9A 2MD9A 2AFDA 2GDXA 2LMLA 2E1MA 4COPA 1OR5A 3CMEP 2K0DX 3CCRP 3H0DA 3H47A 2VLPA 2PEJA 2XZ1C 2AVAA 1HQBA 1K8AQ 1VQOP 5KP6B 2KORA 3RG2A 4MRTC 4U0AA 3Q20A 1X3OA 2PEKA 2JU1A 2M8NA 3CE7A 2VLNA 1Q7YQ 2MVUA 1RO0A 1EOQA 2K92A 2FADA 2N5IA 3G4SP 2LOLA 2QA4P 3DS5A 2EHTA 2JYGA 5JPAA 4U0EA 1Q86Q 3GZMA 2LTEA 2FQ1A 3G21A 1EIAA 2OARA 3CPWO 3G28A 1KLPA 1AF8A 1IMPA 1M90Q 3VRLC 1KC8Q 3CC7P 1M74A 2DGYA 1FR2A 5HV8A 1PEOA 4NEOA 2FQ0A 4IPYA 2VLQA 3U43A 2KGEA 1A8OA 3DPHA 2VSQA 2LIWA 2KGDA 3EJBA 1KQSO 2FVEA 1VQPP 4BPGA 1VQ4P 2QEXP 1VQ8P 1Q81Q 2GYKA 4CA3A 1GXHA 4U0BA 1YJNP 2KGCA 3GZLA 4IZ6A 3CCQP 1YJWP 4QNBA 4PH0A 3G1GA 3CC4P 2N6YA 2CWOA 2MR7A 5F2NA 2KOQA 2KOOA 4M0IA 1YITP 2MF4A 2PEQA 3LRYA 1UNKA 2KG6A 1GXGA 2JO0A 2GDWA 2KG8A 3G26A 4GR6A 3CC2P 3CCLP 1ACPA 2FACA 5KP7B 1PEMA 2OTLP 2XXMA 3CD6P 4XFXA 4BPFA 2PEIA 2N98A 5HGNA 2AF8A 1IMQA 2ERHA 2GZJA 2GDYA 3DS0A 2CQ8A 1VQ6P 2JQ4A 1NQ4A 2L6EA 2VLOA 3DTJA 3CMAP 1W2BO 2KR5A 3DS3A 4U0DA 1VQ9P 3CCVP 3M1MA 4H2XC 4XRQA 2K0XA 1JJ2O 3G1IA 2DNWA 1AYIA 1Q82Q 3CCJP 1NJIQ 3RG6C 5KP8B 1PEUA 1UJZA 4PH1A 3I56P 1VQ7P 2GZIA 4U0FA 2K94A 2CNRA 5HGMA 2XZ0D 2L9FA 2FVFA 5F2KA 2KGAA 4XROA 1GPJA 3E2DA 3DS1A 2PNGA 1E0HA 4H2YC 2BHVA 1K9MQ 4UHPB 5HGOA 4H2WC 1YI2P 5EJDA 2XV6A 2ROQA 2KW2A 1K73Q 1QVFO 3B4QA 3I55P 2L0QA 2JU2A 5DCKA 4XFZA 2PENA 2LIUA 4HKGA 2L4BA 2M8LA 2LF4A 3NY7B 1S72P 2KWLA 2BUOA 3DS2A 1VQLP 1HY8A 2EG5A 3GKLC 3OW2O 3G0VA 1MZ8A 3B5IA 3HZQA 5HGLA 2FAEA 2L22A 1QRJA 2PY8A 2Z44A 2K2QA 2XT1A 3G71P 1N8RQ 1VKUA 2LL8A 3H4EA 3HYBA 2WPTA
chains in the Genus database with same CATH topology
1JJ2O 3G1IA 4IPYA 1YIJP 1BAJA 1Q82Q 1M1KQ 3CCJP 1NJIQ 3RG6C 1A8OA 3NTEA 3DPHA 2ONTA 1KD1Q 1VQNP 1ZMBA 1PEUA 2PEMA 1IUQA 2EFJA 4PH1A 3I56P 5BS1A 1K30A 3CXCO 1KQSO 1VQPP 1VQ7P 1VQ4P 2M8PA 2QEXP 4U0FA 1VQ8P 2E1MA 4COCA 4COPA 3CMEP 1Q81Q 4U0BA 5HGMA 3CCRP 3H0DA 1YJNP 3CCQP 4WYMA 3H47A 2JYLA 5F2KA 2PEJA 1YJWP 1RO2A 4XROA 5BS2A 1PEQA 1M6NA 3CCUP 4QNBA 4PH0A 3P05A 3E2DA 1RNIA 3DS1A 4GR2A 3G1GA 1E6JP 3CC4P 2Z46A 2BHVA 1K9MQ 2CWOA 1K8AQ 5HGOA 1YI2P 1VQOP 5F2NA 2XV6A 1YITP 4M0IA 1YJ9P 2Z45A 2PEQA 3LRYA 1K73Q 2JO0A 1QVFO 4U0AA 3Q20A 5I4TG 3I55P 2PEKA 2PEOA 2M8NA 5DCKA 3G26A 4XFZA 4GR6A 3CC2P 2PENA 3CCLP 1Q7YQ 1RO0A 1EOQA 2OTJP 2M8LA 3DS4A 1PEMA 4U0CA 2OTLP 2XXMA 2LF4A 1VQKP 4XFXA 3CD6P 1S72P 3DS2A 2BUOA 3G4SP 1VQLP 2QA4P 2PEIA 3DS5A 1A43A 4XFYA 2JYGA 5HGNA 5JPAA 1YHQP 2KODA 2EG5A 3G6EP 2P9XA 4U0EA 5F2OA 3OW2O 1Q86Q 3G0VA 3G21A 1EIAA 2OARA 3CPWO 3B5IA 3DS0A 2EIAA 3G28A 3HZQA 5HGLA 1VQ6P 3CMAP 2L6EA 3DTJA 1W2BO 1VQMP 1QVGO 1QRJA 1M90Q 3VRLC 1D1DA 1KC8Q 3DS3A 4U0DA 1VQ9P 2PY8A 3CCVP 1AUMA 3M1MA 2Z44A 1VQ5P 1M6EX 2XT1A 3G71P 3CC7P 3MGEA 1M74A 2BQ1E 2DGYA 1N8RQ 3CCEP 4XRQA 3WBHA 3H4EA 3HYBA 1PEOA 3CCSP 3G29A 3CCMP
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JJ2 O;  1YJN P;  3CCQ P;  3OW2 O;  1Q86 Q;  1K73 Q;  1YIJ P;  3CPW O;  1Q82 Q;  1M1K Q;  1QVF O;  3CCJ P;  1YJW P;  1NJI Q;  3I55 P;  1KD1 Q;  1VQN P;  1VQ6 P;  3CMA P;  1QVG O;  1W2B O;  1VQM P;  3CCU P;  1YJ9 P;  1M90 Q;  3CC2 P;  3CCL P;  1KC8 Q;  1Q7Y Q;  1VQ9 P;  3I56 P;  3CCV P;  3CXC O;  2OTJ P;  1KQS O;  3CC4 P;  1VQP P;  1VQ7 P;  1K9M Q;  1VQ4 P;  2QEX P;  1VQ5 P;  3G71 P;  1K8A Q;  3CC7 P;  2OTL P;  3CD6 P;  1VQK P;  1YI2 P;  1S72 P;  1VQ8 P;  3G4S P;  1N8R Q;  1VQL P;  3CCE P;  2QA4 P;  1VQO P;  3CME P;  1Q81 Q;  1YHQ P;  1YIT P;  3CCR P;  3CCS P;  3G6E P;  3CCM P; 
#chains in the Genus database with same CATH topology
 1BAJ A;  1M1K Q;  3GJN A;  2JAZ A;  1VHN A;  2LPK A;  1VQN P;  2ONT A;  2K93 A;  1F80 D;  1ZNV A;  1ZMB A;  2PEM A;  1L0I A;  2EHS A;  4PWV B;  5BS1 A;  1K30 A;  3CXC O;  5CZD B;  2N50 A;  2M8P A;  2CGQ A;  4COC A;  4QKO A;  4PXH B;  2FHS C;  1T8K A;  2CG5 B;  7CEI A;  2KG9 A;  4WYM A;  2JYL A;  2GZE A;  2N6Z A;  1RO2 A;  1BXI A;  5BS2 A;  1PEQ A;  1M6N A;  3CCU P;  1CEI A;  3P05 A;  1RNI A;  2QNW A;  4GR2 A;  1E6J P;  2Z46 A;  1Z6M A;  2M5R A;  2JB0 A;  2MY5 A;  1YJ9 P;  2Z45 A;  2JBG A;  5EW5 E;  1DNY A;  2MR8 A;  5I4T G;  2PEO A;  4R0M A;  3EJE A;  2X2B A;  2OTJ P;  3DS4 A;  4U0C A;  1VQK P;  2GZF A;  2KOS A;  4F37 A;  1A43 A;  4XFY A;  1YHQ P;  2AFE A;  2KOD A;  4BPH A;  3G6E P;  2K5X A;  3EJD A;  2P9X A;  5F2O A;  3LMO A;  2K0Y A;  2EIA A;  2GZG A;  1QVG O;  1VQM P;  2MVV A;  1D1D A;  2FQ2 A;  1AUM A;  5HVC A;  1L0H A;  1VQ5 P;  2FVA A;  1M6E X;  1EMV A;  3MGE A;  2BQ1 E;  3CCE P;  2LKI A;  3WBH A;  2KOP A;  1DV5 A;  3CCS P;  3G29 A;  3CCM P;  2N5H A;  1YIJ P;  3NTE A;  1KD1 Q;  2NO8 A;  2JGP A;  1IUQ A;  2EFJ A;  4DG9 A;  2MD9 A;  2AFD A;  2GDX A;  2LML A;  2E1M A;  4COP A;  1OR5 A;  3CME P;  2K0D X;  3CCR P;  3H0D A;  3H47 A;  2VLP A;  2PEJ A;  2XZ1 C;  2AVA A;  1HQB A;  1K8A Q;  1VQO P;  5KP6 B;  2KOR A;  3RG2 A;  4MRT C;  4U0A A;  3Q20 A;  1X3O A;  2PEK A;  2JU1 A;  2M8N A;  3CE7 A;  2VLN A;  1Q7Y Q;  2MVU A;  1RO0 A;  1EOQ A;  2K92 A;  2FAD A;  2N5I A;  3G4S P;  2LOL A;  2QA4 P;  3DS5 A;  2EHT A;  2JYG A;  5JPA A;  4U0E A;  1Q86 Q;  3GZM A;  2LTE A;  2FQ1 A;  3G21 A;  1EIA A;  2OAR A;  3CPW O;  3G28 A;  1KLP A;  1AF8 A;  1IMP A;  1M90 Q;  3VRL C;  1KC8 Q;  3CC7 P;  1M74 A;  2DGY A;  1FR2 A;  5HV8 A;  1PEO A;  4NEO A;  2FQ0 A;  4IPY A;  2VLQ A;  3U43 A;  2KGE A;  1A8O A;  3DPH A;  2VSQ A;  2LIW A;  2KGD A;  3EJB A;  1KQS O;  2FVE A;  1VQP P;  4BPG A;  1VQ4 P;  2QEX P;  1VQ8 P;  1Q81 Q;  2GYK A;  4CA3 A;  1GXH A;  4U0B A;  1YJN P;  2KGC A;  3GZL A;  4IZ6 A;  3CCQ P;  1YJW P;  4QNB A;  4PH0 A;  3G1G A;  3CC4 P;  2N6Y A;  2CWO A;  2MR7 A;  5F2N A;  2KOQ A;  2KOO A;  4M0I A;  1YIT P;  2MF4 A;  2PEQ A;  3LRY A;  1UNK A;  2KG6 A;  1GXG A;  2JO0 A;  2GDW A;  2KG8 A;  3G26 A;  4GR6 A;  3CC2 P;  3CCL P;  1ACP A;  2FAC A;  5KP7 B;  1PEM A;  2OTL P;  2XXM A;  3CD6 P;  4XFX A;  4BPF A;  2PEI A;  2N98 A;  5HGN A;  2AF8 A;  1IMQ A;  2ERH A;  2GZJ A;  2GDY A;  3DS0 A;  2CQ8 A;  1VQ6 P;  2JQ4 A;  1NQ4 A;  2L6E A;  2VLO A;  3DTJ A;  3CMA P;  1W2B O;  2KR5 A;  3DS3 A;  4U0D A;  1VQ9 P;  3CCV P;  3M1M A;  4H2X C;  4XRQ A;  2K0X A;  1JJ2 O;  3G1I A;  2DNW A;  1AYI A;  1Q82 Q;  3CCJ P;  1NJI Q;  3RG6 C;  5KP8 B;  1PEU A;  1UJZ A;  4PH1 A;  3I56 P;  1VQ7 P;  2GZI A;  4U0F A;  2K94 A;  2CNR A;  5HGM A;  2XZ0 D;  2L9F A;  2FVF A;  5F2K A;  2KGA A;  4XRO A;  1GPJ A;  3E2D A;  3DS1 A;  2PNG A;  1E0H A;  4H2Y C;  2BHV A;  1K9M Q;  4UHP B;  5HGO A;  4H2W C;  1YI2 P;  5EJD A;  2XV6 A;  2ROQ A;  2KW2 A;  1K73 Q;  1QVF O;  3B4Q A;  3I55 P;  2L0Q A;  2JU2 A;  5DCK A;  4XFZ A;  2PEN A;  2LIU A;  4HKG A;  2L4B A;  2M8L A;  2LF4 A;  3NY7 B;  1S72 P;  2KWL A;  2BUO A;  3DS2 A;  1VQL P;  1HY8 A;  2EG5 A;  3GKL C;  3OW2 O;  3G0V A;  1MZ8 A;  3B5I A;  3HZQ A;  5HGL A;  2FAE A;  2L22 A;  1QRJ A;  2PY8 A;  2Z44 A;  2K2Q A;  2XT1 A;  3G71 P;  1N8R Q;  1VKU A;  2LL8 A;  3H4E A;  3HYB A;  2WPT A; 
#chains in the Genus database with same CATH homology
 1JJ2 O;  3G1I A;  4IPY A;  1YIJ P;  1BAJ A;  1Q82 Q;  1M1K Q;  3CCJ P;  1NJI Q;  3RG6 C;  1A8O A;  3NTE A;  3DPH A;  2ONT A;  1KD1 Q;  1VQN P;  1ZMB A;  1PEU A;  2PEM A;  1IUQ A;  2EFJ A;  4PH1 A;  3I56 P;  5BS1 A;  1K30 A;  3CXC O;  1KQS O;  1VQP P;  1VQ7 P;  1VQ4 P;  2M8P A;  2QEX P;  4U0F A;  1VQ8 P;  2E1M A;  4COC A;  4COP A;  3CME P;  1Q81 Q;  4U0B A;  5HGM A;  3CCR P;  3H0D A;  1YJN P;  3CCQ P;  4WYM A;  3H47 A;  2JYL A;  5F2K A;  2PEJ A;  1YJW P;  1RO2 A;  4XRO A;  5BS2 A;  1PEQ A;  1M6N A;  3CCU P;  4QNB A;  4PH0 A;  3P05 A;  3E2D A;  1RNI A;  3DS1 A;  4GR2 A;  3G1G A;  1E6J P;  3CC4 P;  2Z46 A;  2BHV A;  1K9M Q;  2CWO A;  1K8A Q;  5HGO A;  1YI2 P;  1VQO P;  5F2N A;  2XV6 A;  1YIT P;  4M0I A;  1YJ9 P;  2Z45 A;  2PEQ A;  3LRY A;  1K73 Q;  2JO0 A;  1QVF O;  4U0A A;  3Q20 A;  5I4T G;  3I55 P;  2PEK A;  2PEO A;  2M8N A;  5DCK A;  3G26 A;  4XFZ A;  4GR6 A;  3CC2 P;  2PEN A;  3CCL P;  1Q7Y Q;  1RO0 A;  1EOQ A;  2OTJ P;  2M8L A;  3DS4 A;  1PEM A;  4U0C A;  2OTL P;  2XXM A;  2LF4 A;  1VQK P;  4XFX A;  3CD6 P;  1S72 P;  3DS2 A;  2BUO A;  3G4S P;  1VQL P;  2QA4 P;  2PEI A;  3DS5 A;  1A43 A;  4XFY A;  2JYG A;  5HGN A;  5JPA A;  1YHQ P;  2KOD A;  2EG5 A;  3G6E P;  2P9X A;  4U0E A;  5F2O A;  3OW2 O;  1Q86 Q;  3G0V A;  3G21 A;  1EIA A;  2OAR A;  3CPW O;  3B5I A;  3DS0 A;  2EIA A;  3G28 A;  3HZQ A;  5HGL A;  1VQ6 P;  3CMA P;  2L6E A;  3DTJ A;  1W2B O;  1VQM P;  1QVG O;  1QRJ A;  1M90 Q;  3VRL C;  1D1D A;  1KC8 Q;  3DS3 A;  4U0D A;  1VQ9 P;  2PY8 A;  3CCV P;  1AUM A;  3M1M A;  2Z44 A;  1VQ5 P;  1M6E X;  2XT1 A;  3G71 P;  3CC7 P;  3MGE A;  1M74 A;  2BQ1 E;  2DGY A;  1N8R Q;  3CCE P;  4XRQ A;  3WBH A;  3H4E A;  3HYB A;  1PEO A;  3CCS P;  3G29 A;  3CCM P; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...