The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
93
|
sequence length |
363
|
structure length |
358
|
Chain Sequence |
LQEVIGWGLIGWKYGPIQCEGLANLGVTQIACAEKRFLILSRNGRVYTQAYNSDTLAPQLVQGLASRNIVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVVKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKPEPAALPGLDTKHIVGIACGPAQSFAWSSCSEWSI
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| molecule keywords |
E3 ubiquitin-protein ligase HERC2
|
| publication title |
Structure of the first RCC1-like domain of HERC2
rcsb |
| source organism |
Homo sapiens
|
| molecule tags |
Ligase
|
| total genus |
93
|
| structure length |
358
|
| sequence length |
363
|
| chains with identical sequence |
B, C
|
| ec nomenclature |
ec
2.3.2.26: HECT-type E3 ubiquitin transferase. |
| pdb deposition date | 2013-06-03 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF00415 | RCC1 | Regulator of chromosome condensation (RCC1) repeat |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Beta | 7 Propeller | Methylamine Dehydrogenase; Chain H | Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II |
#chains in the Genus database with same CATH superfamily 4DNW A; 4L1M A; 4D9S A; 4NC4 A; 4NBM A; 1JTD B; 4DNV A; 3OF7 A; 3KCI A; 4JHP C; 4O2W A; 3QI0 A; 1A12 A; 3QHY B; 1I2M B; 4QAM A; 4JHN A; 4NAA A; 4DNU A; 3MVD K; #chains in the Genus database with same CATH topology 4G1M A; 1QFM A; 2GNQ A; 2XE4 A; 3IJC A; 2AGY A; 2J57 G; 5FLX g; 5JWZ A; 3PXW D; 3OL2 B; 4PBZ A; 4BP8 A; 1JTD B; 1UTC A; 2HU8 A; 2O9K A; 3C99 A; 2G9A A; 5EMJ B; 4D6V A; 3FM0 A; 5CYK B; 5H1M A; 2OJY A; 1SQJ A; 2XL3 A; 4Y5R D; 5FKT A; 4I79 A; 3I8C A; 2PM9 A; 4AN0 A; 5M5T A; 5C2W B; 2PM6 B; 3HFQ A; 2VDN A; 4GGD A; 3I7L A; 3EI4 B; 2QZP A; 5GXH A; 5C2V B; 2B5M A; 3GD1 I; 3BG1 A; 4XEI C; 3SBR A; 3RFH A; 5AFU 3; 2VDR A; 3NVX A; 2AGZ A; 4DNW A; 4JT6 C; 2XL2 A; 3NVN A; 3OKW A; 3UVN A; 4QL1 A; 3DDU A; 3KRW B; 2H6Q A; 2YNN A; 4AN1 A; 3N0D A; 3UVK A; 4JSP C; 3OKY B; 2IUQ A; 4J77 A; 1VZ3 A; 3K72 A; 4FA4 D; 2Q7Q A; 5C86 A; 3EQ7 A; 1GOG A; 2MTA H; 1Q47 A; 3ZWL B; 1P22 A; 2I0S A; 5E6U A; 2VDM A; 3JRP A; 2IUV A; 4X3E A; 2EIE A; 1I2M B; 1GOF A; 4ERZ A; 4LG8 A; 4J82 A; 2H68 A; 5B4W A; 3CFS B; 4GGA A; 3VI3 A; 4L1M A; 3ODT A; 4Z7N A; 3B7F A; 2Z2P A; 3JZN A; 1GOT B; 5H17 A; 1N6E A; 2B5N A; 3NIF A; 3I8E A; 1NR0 A; 2VZ3 A; 1L0Q A; 2VDL A; 4QT8 A; 1UOO A; 2HKM A; 3MXX A; 3V5W B; 4PNK B; 4X61 B; 4Z7O A; 3JAM g; 1B9Y A; 3AL8 B; 3I7O A; 5TF2 A; 3MUN A; 4BCC A; 4JHN A; 4L3G D; 4NAA A; 4PSW B; 3EI2 A; 3DXM C; 5GSA A; 4H5I A; 4ESG A; 2BKL A; 3SWS D; 3IUJ A; 1A0R B; 3MKQ A; 5I5I A; 1NEX B; 1PEV A; 2OVR B; 3EI1 A; 3O4G A; 4E5Z B; 2I0R A; 4JT5 C; 3F3G A; 4AOW A; 1UOQ A; 3V4V A; 5HE3 B; 3OW8 A; 2IUP A; 2YBA A; 3PXS D; 3I7H A; 1GP2 B; 2HU5 A; 1JJU B; 2YNP A; 4O3T B; 3ZDY A; 4IMM A; 4A09 A; 1BPO A; 4J79 A; 1R5M A; 5FA5 B; 5M5S A; 1RI6 A; 3IVM A; 4CY3 A; 3IJ1 A; 4A11 B; 4Z7Q A; 2HJ4 A; 3UKR C; 3J81 g; 4FA9 D; 4JSV C; 3UVO A; 2I0T A; 1T2X A; 4GM9 A; 2VDO A; 4AEZ A; 4Y7R A; 1E5T A; 4NEN A; 4K3J B; 4QQE A; 4CI3 A; 4J0W A; 3EI3 A; 1YFQ A; 5H14 A; 2I3T A; 2EIC A; 4N14 A; 5HE2 B; 5CXB B; 2XDW A; 3AFC A; 4JSX C; 4J8B A; 1QFS A; 4ZN4 A; 4OZU A; 3JRO A; 3PE7 A; 2B4E A; 3I7K A; 4TZ4 A; 4D9S A; 3N0E A; 4BUJ C; 3ZDX A; 3SFZ A; 5TEF A; 4J84 A; 1VYH C; 2CN3 A; 3NIG A; 3OL2 A; 2GC4 A; 1TYE A; 1C9L A; 2IUR A; 5CYK A; 3C75 H; 1OLZ A; 4BL0 A; 3ZDZ A; 4PXW A; 1VE7 A; 4GM8 A; 1A12 A; 4H5J A; 1JV2 A; 3C5M A; 3L4M D; 3OKT A; 4DNU A; 3MVD K; 5IT9 g; 5EMK B; 2CO0 C; 2P9P C; 4CY1 A; 2PM9 B; 3EQ9 A; 1SQ9 A; 5M5V A; 1FWX A; 4O3U B; 3MUO A; 3RMZ D; 4D0K A; 4A0A B; 1N6D A; 3V7D B; 4O02 A; 2CN2 A; 4FHL A; 3UVL A; 1H2W A; 4G56 B; 2HXC A; 4JHP C; 4MMX A; 2P9K C; 3IUQ A; 5HDB A; 5FKS A; 3BG0 A; 3C9C A; 2EID A; 2P9N C; 5EAP A; 5IC7 A; 3T3P A; 5EM2 A; 5CXC A; 1JMZ B; 4EWR A; 5K1C C; 3DWL C; 3EWE A; 4A2L A; 3IUR A; 3RLM D; 4NC4 A; 4IA9 A; 5TEE A; 5HE1 B; 2AGX A; 3IUM A; 3ORV D; 2OVQ B; 4K3I D; 4L3H D; 4AMZ A; 2HYE A; 1TBG A; 5IGO A; 3I7P A; 3IIW A; 1M1X A; 3K27 A; 2H14 A; 2OK4 A; 5C9Z B; 5GXI A; 3GFC A; 4L1Q D; 5GMK n; 3FCS A; 1GG2 B; 2HKR A; 1TYQ C; 1PGU A; 4PBY A; 3RSE C; 3RN0 D; 1UOP A; 3RFG A; 2H9L A; 2AH0 A; 4CZV A; 3K6S A; 3DXK C; 4GQB B; 5A2Q g; 3AH8 B; 4R7A B; 3PVW B; 3PSC B; 5HYN B; 5C92 A; 1L5G A; 3ULE C; 2YNO A; 3JPX A; 4E54 A; 2JKX A; 2TRC B; 2H3X A; 3J80 g; 3MZL A; 2H13 A; 1PI6 A; 1O6G A; 4XYI A; 3EI2 B; 4GQ2 P; 2XU7 A; 4UM9 A; 4CI1 A; 4GQ1 A; 2VDK A; 2AGW A; 3A0F A; 3EG6 A; 3PXT D; 1JMX B; 3QI0 A; 5K19 A; 3JB9 L; 1K8K C; 1H2Z A; 3EI1 B; 4QAM A; 2HU7 A; 2OIZ A; 4A7J A; 4BH6 A; 5I5M A; 2HES X; 3IJ0 A; 4X60 B; 3I89 A; 5E6S A; 2CO0 A; 3IUN A; 1ERJ A; 4FB1 D; 2H9N A; 5E6R A; 5SXM A; 3I7N A; 4A0B A; 4A08 B; 4G55 A; 4J87 A; 3VH0 A; 2GC7 A; 4J86 A; 5EAR A; 3SLE D; 3VI4 A; 1XKS A; 2W18 A; 2XZG A; 5FKR A; 3SN6 B; 4LG9 A; 3SXT D; 1E8N A; 2P9L C; 1QNI A; 5EAM A; 1U2V C; 3V4P A; 3CIK B; 3IUL A; 2EBS A; 3O4I A; 4O1Q D; 5M5U A; 2AQ5 A; 3EI3 B; 4JSN C; 3EU7 A; 4ZOY A; 5I5J A; 4MK0 B; 2H9P A; 4AMY A; 4ZOV A; 3SCY A; 3OTT A; 4ERY A; 2CE9 A; 2HJB A; 1GOH A; 2J55 H; 4X63 B; 4CY5 A; 4GMB A; 2OK6 A; 4IRZ A; 1B9X A; 2VDQ A; 4AX4 A; 4CY2 A; 3W15 A; 3QHY B; 2BBK H; 4FAN D; 2WQ8 A; 3EI4 A; 2H6K A; 4WK2 A; 3FGB A; 4RE5 A; 3UR4 A; 5M5R A; 2J56 H; 4CZX A; 4JD2 C; 4WJK A; 4BCB A; 5TDH B; 1MG2 A; 4FWW A; 3JZG A; 3BWS A; 3OF7 A; 4YVD A; 4O45 A; 4QRJ A; 3ZE0 A; 5HQG A; 4L9O A; 4A0A A; 3OKY A; 1C9I A; 3AL9 A; 5AJA A; 3SHF A; 4OWR A; 2OVP B; 3I2N A; 5AMS A; 4FA1 D; 1MDA H; 2YMU A; 4CC9 A; 5IGQ A; 3MMY A; 3ZE2 A; 2H47 A; 4CI2 A; 3CFV A; 2UZY B; 4BCD A; 4GZ8 A; 4GGC A; 3T3M A; 4CZY A; 1MG3 A; 2IAA A; 3O4J A; 1JOF A; 3NID A; 2AGL A; 2QXV A; 3FRX A; 4PC0 A; 4J73 A; 2P9S C; 2IWF A; 5KDO B; 3SBQ A; 5EM2 B; 3EMH A; 4UI9 R; 5CXC B; 2H9M A; 1PBY B; 5IJ8 E; 4O2W A; 2QR5 A; 2YB8 B; 4MMZ A; 1O6F A; 2B5L A; 3DSM A; 3P4F A; 2Z2O A; 2AH1 A; 4O9D A; 5FQD A; 3F3P A; 2P9U C; 4U1E I; 1S4U X; 3AL8 A; 4NBM A; 3NVQ A; 3ZE1 A; 4WK0 A; 2P9I C; 2Z2N A; 4WK4 A; 5IJ7 E; 1N6F A; 3O4H A; 4MMY A; 1H2Y A; 4NSX A; 3V9F A; 4PSX B; 4HDJ A; 3SMR A; 4E5Z A; 5FKQ A; 1SHY B; 3UVM A; 3F3F A; 1H2X A; 3FCU A; 4J8G A; 3E0C A; 3JZH A; 2I3S A; 4U7A A; 2CNX A; 3VGZ A; 4E54 B; 3KRX B; 3SJL D; 2VZ1 A; 2VDP A; 5M61 A; 4ZOX A; 1VZ2 A; 1XIP A; 5EML B; 2BCJ B; 3GC3 B; 5EAL A; 1YR2 A; 4RE6 A; 2QC5 A; 4A11 A; 4FA5 D; 3VA6 A; 4KFM B; 4XYH A; 4BP9 A; 4J78 A; 3KCI A; 4A09 B; 3IKO A; 1U8C A; 2UZX B; 4ZOZ A; 3RRM C; 1VE6 A; 2PM7 B; 4UM8 A; 1XHM A; 4ERQ A; 2H6N A; 3IJE A; 4GM3 A; 5EMM B; 3SVW D; 3MZK A; 4G1E A; 4A08 A; 1GXR A; 3MKS B; 2XYI A; 5HE0 B; 2VC2 A; 3RN1 D; 3K71 A; 4A0B B; 5FXY A; 5THA A; 3DM0 A; 3GRE A; 5CXB A; 4DNV A; 3K26 A; 1E8M A; 4CI8 A; 3UKU C; 4JXM A; 5FFO A; 3SBP A; 2CE8 A; 2IWK A; 2EIB A; 4ES0 A; 2PBI B; 3L4O D; 4J81 A; 1OMW B; 4Z8L A; 4A2M A; 3PVU B; 3PSL A; 4FAV D; 4J0X A; 1K3I A; 4LGN A; 1K32 A; 2G99 A; 3EQ8 A; 3IIY A; 3U4Y A; 5FFG A; 1U4C A; #chains in the Genus database with same CATH homology 4DNW A; 4L1M A; 4D9S A; 4NC4 A; 4NBM A; 1JTD B; 4DNV A; 3OF7 A; 3KCI A; 4JHP C; 4O2W A; 3QI0 A; 1A12 A; 3QHY B; 1I2M B; 4QAM A; 4JHN A; 4NAA A; 4DNU A; 3MVD K;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
