3M1MA

Crystal structure of the primase-polymerase from sulfolobus islandicus
Total Genus 121
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
121
sequence length
331
structure length
320
Chain Sequence
SSERIRYAKWFLEHGFNIIPIDPESKKPVLKEWQKYSHEMPSDEEKQRFLKMIEEGYNYAIPGGQKGLVILDFESKEKLKAWIGESALEELCRKTLCTNTVHGGIHIYVLSNDIPPHKINPLFEENGKGIIDLQSYNSYVLGLGSCVNHLHCTTDKCPWKEQNYTTCYTLYNELKEISKVDLKSLLRFLAEKGKRLGITLSKTAKEWLEGEELRKELVKRDSGKPVEKIKEEICTKSPPKLIKEIICENKTYADVNIDRSRGDWHVILYLMKHGVTDPDKILELLPRDSKAKENEKWNTQKYFVITLSKAWSVVKKYLEA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Replication
source organism Sulfolobus islandicus
publication title The archaeo-eukaryotic primase of plasmid pRN1 requires a helix bundle domain for faithful primer synthesis
pubmed doi rcsb
molecule keywords ORF904
total genus 121
structure length 320
sequence length 331
ec nomenclature
pdb deposition date 2010-03-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09250 Prim-Pol Bifunctional DNA primase/polymerase, N-terminal
A PF13010 pRN1_helical Primase helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.130 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A 3m1mA01
1.10.1240.50 Mainly Alpha Orthogonal Bundle Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 3m1mA03
3.30.2250.10 Alpha Beta 2-Layer Sandwich Prim-pol fold Bifunctional DNA primase/polymerase domain 3m1mA02
3H20A 3M1MA 1RNIA 1RO0A 1RO2A
chains in the Genus database with same CATH superfamily
2OARA 5KP7B 2ROQA 3DTJA 1YIJP 3Q20A 1Q7YQ 1VQ8P 4U0FA 2MY5A 1EIAA 4BPFA 1AUMA 3B4QA 4U0AA 2BHVA 3CCEP 2CGQA 3CE7A 2JB0A 1QSAA 2AF8A 4COPA 2EIAA 3DS0A 5F2KA 2FACA 1W53A 2OTJP 1QVGO 1M1KQ 2FQ0A 4U0BA 4PH1A 2NO8A 2K93A 2LL8A 2K0YA 3CMAP 1DNYA 2M5RA 4U0CA 3CCRP 2J70A 3H20A 1Q86Q 1NQ4A 2DGYA 3G21A 4BPGA 1OR5A 1A43A 2LTEA 2M8NA 2Z46A 3CC4P 2L6EA 3H4EA 2MD9A 1ZMBA 2GZFA 4G86A 1K7YA 1L0IA 2KOSA 2XT1A 3NY7B 3CD6P 2LIUA 4NEOA 1L0HA 2AFDA 2ONTA 2KG8A 2L0QA 2JBGA 2N6ZA 1SLYA 3DS5A 2JU2A 2PEIA 2GDXA 3HYBA 4BPHA 3P05A 1RNIA 4PH0A 2KODA 1EOQA 4UHPB 2FAEA 4XFXA 3E2DA 4U0DA 2LF4A 1Q82Q 3G6EP 2PNGA 2GDWA 2Z44A 2WPTA 2KGCA 2JU1A 3CCMP 1VQ5P 1N8RQ 3DS3A 3CMEP 2LMLA 4CA3A 2KWLA 5EJDA 2N5IA 2XZ0D 2CWOA 4HEHA 3I56P 2JQ4A 2GDYA 2BUOA 2EFJA 1VQ7P 3G1IA 5F2OA 1BMTA 4HH3C 3WHPA 4XFYA 4H2XC 2KR5A 2KORA 1VKUA 1VQNP 3M1MA 2N6YA 5HGOA 3G71P 1HY8A 4U0EA 1M90Q 3H47A 2LKIA 1GXHA 2DNWA 1VQLP 2K0XA 4GR6A 4QKOA 2PEKA 2EHTA 2MVVA 3G0VA 2MR8A 2VLQA 1YJ9P 2E1MA 3G29A 3DS1A 1E0HA 4JGIA 2K92A 2AVAA 3OW2O 1ACPA 5I4TG 2FQ1A 3RG2A 1YI2P 3HZQA 2XZ1C 1S72P 2JYLA 4GR2A 3CCVP 1IMPA 4IZ6A 4WYMA 1UZ3A 1SUYA 2KGDA 1MZ8A 4X8QA 1K73Q 5F2NA 1M6NA 1AF8A 2AFEA 5HGMA 3EJDA 1JJ2O 5C5EA 5KP8B 2JGPA 3G28A 1BAJA 1BXIA 2PEQA 2KOOA 7CEIA 1R8JA 1YHQP 2K2QA 2JAZA 1KQSO 2KOPA 1VQ4P 2K0DX 1E6JP 2VLPA 2LOLA 3EJEA 5KP6B 1IMQA 4PXHB 1R5QA 2FVAA 2FVFA 1UTUA 1EMVA 1F80D 4H2YC 3G4SP 1DV5A 3GZMA 5HGLA 1K30A 4COCA 3EZXA 1VQ6P 2CNRA 2MR7A 2XV6A 5BS2A 3WBHA 1T8KA 4M0IA 3CCUP 2XXMA 2N5HA 1Z6MA 1Q81Q 5C8DA 4IPYA 1NJIQ 2JO0A 5HV8A 1RO2A 2I2XB 2X2BA 2MF4A 2GZJA 2PY8A 1M6EX 2L4BA 1K9MQ 3CCSP 3DS4A 1RO0A 1K8AQ 2MVUA 2N50A 2GZIA 2KGAA 1KLPA 2PEJA 3L9TA 2KG9A 2FADA 3IV9A 4DG9A 1YJWP 2GYKA 2Z45A 3DPHA 3CCJP 1GPJA 1CEIA 1QTEA 3G26A 5HGNA 5DCKA 4QNBA 2K94A 1YITP 4XROA 2VLNA 1AYIA 2VLOA 3RG6C 2FHSC 3I55P 4F37A 2ERHA 1VQOP 2K5XA 4XFZA 1VQ9P 2QA4P 3VRLC 2L22A 2L9FA 1YJNP 2EG5A 1VQKP 3LRYA 1W2BO 2FMME 2LPKA 5BS1A 4H2WC 1A8OA 5EW5E 2FQ2A 2LIWA 2QNWA 2GZEA 1Q6BA 1V2ZA 4XRQA 1KD1Q 3B5IA 3CC2P 2KW2A 1QVFO 2GZGA 1UNKA 1VHNA 1ZNVA 1D1DA 3EJBA 3H0DA 2CQ8A 3LMOA 1Q6AA 2KGEA 2PEOA 2KG6A 4PWVB 1K98A 3BULA 1KC8Q 4HKGA 1VQPP 2CG5B 3CXCO 3CCQP 2PENA 1UJZA 2KOQA 2QEXP 1VQMP 2JYGA 1QRJA 2P9XA 3CC7P 3IVAA 3CCLP 2PEMA 1IUQA 3GJNA 2J6ZA 2EHSA 2M8LA 2M8PA 3NTEA 3CPWO 5JPAA 1X3OA 3BJDA 2N98A 3GZLA 5CZDB 2PBIA 2FVEA 4M0MA 3U43A 1SV1A 4R0MA 2VSQA 1HQBA 3MGEA 3DS2A 2J6YA 1GXGA 1FR2A 3GKLC 3G1GA 4MRTC 2OTLP 5HVCA 1M74A
chains in the Genus database with same CATH topology
3I55P 2Z44A 3G28A 1BAJA 2PEQA 2OARA 1Q7YQ 3DTJA 1YIJP 3Q20A 1VQ8P 4U0FA 1EIAA 1VQOP 1YHQP 1AUMA 4XFZA 3CCMP 1VQ5P 4U0AA 1VQ9P 2BHVA 3CCEP 1N8RQ 3DS3A 1KQSO 3CMEP 2QA4P 3VRLC 1VQ4P 1YJNP 1E6JP 4COPA 2EIAA 2CWOA 3DS0A 5F2KA 2EG5A 1VQKP 3I56P 3LRYA 1W2BO 2BUOA 2EFJA 1VQ7P 3G1IA 5F2OA 2FMME 1UTUA 2OTJP 1QVGO 1M1KQ 4XFYA 5BS1A 4U0BA 4PH1A 3G4SP 1A8OA 3CMAP 5HGLA 3CC7P 1K30A 4COCA 4U0CA 4XRQA 3CCRP 3B5IA 1KD1Q 1VQNP 1Q86Q 3H20A 3M1MA 1VQ6P 5HGOA 2DGYA 3G71P 4U0EA 3G21A 3CC2P 1QVFO 2XV6A 1M90Q 5BS2A 3WBHA 1A43A 3H47A 4M0IA 2M8NA 2Z46A 3CCUP 3CC4P 2XXMA 1Q81Q 1D1DA 2L6EA 3H4EA 1VQLP 3H0DA 4IPYA 4GR6A 1NJIQ 2JO0A 1RO2A 1ZMBA 2PEKA 2PEOA 1KC8Q 1VQPP 3G0VA 3CXCO 2PY8A 3CCQP 2XT1A 2PENA 3CD6P 2QEXP 1M6EX 1VQMP 2JYGA 1QRJA 2P9XA 1YJ9P 1K9MQ 2E1MA 3CCSP 2PEMA 3DS4A 3G29A 3CCLP 1RO0A 1IUQA 2ONTA 3DS1A 1K8AQ 3OW2O 2M8LA 5I4TG 2M8PA 3NTEA 3CPWO 3DS5A 5JPAA 2PEJA 1YI2P 3HZQA 2PEIA 2PBIA 4M0MA 3L9TA 1S72P 3HYBA 2JYLA 4GR2A 1YJWP 3P05A 1RNIA 2KODA 1EOQA 3MGEA 4PH0A 2Z45A 3DPHA 3CCJP 3DS2A 3CCVP 4WYMA 4XFXA 1UZ3A 3E2DA 3G26A 5HGNA 5DCKA 4QNBA 4U0DA 2LF4A 4X8QA 1K73Q 5F2NA 1M6NA 1YITP 4XROA 3G1GA 5HGMA 3G6EP 1Q82Q 2OTLP 1JJ2O 3RG6C 1M74A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3H20 A;  3M1M A;  1RNI A;  1RO0 A;  1RO2 A; 
#chains in the Genus database with same CATH topology
 2OAR A;  5KP7 B;  2ROQ A;  3DTJ A;  1YIJ P;  3Q20 A;  1Q7Y Q;  1VQ8 P;  4U0F A;  2MY5 A;  1EIA A;  4BPF A;  1AUM A;  3B4Q A;  4U0A A;  2BHV A;  3CCE P;  2CGQ A;  3CE7 A;  2JB0 A;  1QSA A;  2AF8 A;  4COP A;  2EIA A;  3DS0 A;  5F2K A;  2FAC A;  1W53 A;  2OTJ P;  1QVG O;  1M1K Q;  2FQ0 A;  4U0B A;  4PH1 A;  2NO8 A;  2K93 A;  2LL8 A;  2K0Y A;  3CMA P;  1DNY A;  2M5R A;  4U0C A;  3CCR P;  2J70 A;  3H20 A;  1Q86 Q;  1NQ4 A;  2DGY A;  3G21 A;  4BPG A;  1OR5 A;  1A43 A;  2LTE A;  2M8N A;  2Z46 A;  3CC4 P;  2L6E A;  3H4E A;  2MD9 A;  1ZMB A;  2GZF A;  4G86 A;  1K7Y A;  1L0I A;  2KOS A;  2XT1 A;  3NY7 B;  3CD6 P;  2LIU A;  4NEO A;  1L0H A;  2AFD A;  2ONT A;  2KG8 A;  2L0Q A;  2JBG A;  2N6Z A;  1SLY A;  3DS5 A;  2JU2 A;  2PEI A;  2GDX A;  3HYB A;  4BPH A;  3P05 A;  1RNI A;  4PH0 A;  2KOD A;  1EOQ A;  4UHP B;  2FAE A;  4XFX A;  3E2D A;  4U0D A;  2LF4 A;  1Q82 Q;  3G6E P;  2PNG A;  2GDW A;  2Z44 A;  2WPT A;  2KGC A;  2JU1 A;  3CCM P;  1VQ5 P;  1N8R Q;  3DS3 A;  3CME P;  2LML A;  4CA3 A;  2KWL A;  5EJD A;  2N5I A;  2XZ0 D;  2CWO A;  4HEH A;  3I56 P;  2JQ4 A;  2GDY A;  2BUO A;  2EFJ A;  1VQ7 P;  3G1I A;  5F2O A;  1BMT A;  4HH3 C;  3WHP A;  4XFY A;  4H2X C;  2KR5 A;  2KOR A;  1VKU A;  1VQN P;  3M1M A;  2N6Y A;  5HGO A;  3G71 P;  1HY8 A;  4U0E A;  1M90 Q;  3H47 A;  2LKI A;  1GXH A;  2DNW A;  1VQL P;  2K0X A;  4GR6 A;  4QKO A;  2PEK A;  2EHT A;  2MVV A;  3G0V A;  2MR8 A;  2VLQ A;  1YJ9 P;  2E1M A;  3G29 A;  3DS1 A;  1E0H A;  4JGI A;  2K92 A;  2AVA A;  3OW2 O;  1ACP A;  5I4T G;  2FQ1 A;  3RG2 A;  1YI2 P;  3HZQ A;  2XZ1 C;  1S72 P;  2JYL A;  4GR2 A;  3CCV P;  1IMP A;  4IZ6 A;  4WYM A;  1UZ3 A;  1SUY A;  2KGD A;  1MZ8 A;  4X8Q A;  1K73 Q;  5F2N A;  1M6N A;  1AF8 A;  2AFE A;  5HGM A;  3EJD A;  1JJ2 O;  5C5E A;  5KP8 B;  2JGP A;  3G28 A;  1BAJ A;  1BXI A;  2PEQ A;  2KOO A;  7CEI A;  1R8J A;  1YHQ P;  2K2Q A;  2JAZ A;  1KQS O;  2KOP A;  1VQ4 P;  2K0D X;  1E6J P;  2VLP A;  2LOL A;  3EJE A;  5KP6 B;  1IMQ A;  4PXH B;  1R5Q A;  2FVA A;  2FVF A;  1UTU A;  1EMV A;  1F80 D;  4H2Y C;  3G4S P;  1DV5 A;  3GZM A;  5HGL A;  1K30 A;  4COC A;  3EZX A;  1VQ6 P;  2CNR A;  2MR7 A;  2XV6 A;  5BS2 A;  3WBH A;  1T8K A;  4M0I A;  3CCU P;  2XXM A;  2N5H A;  1Z6M A;  1Q81 Q;  5C8D A;  4IPY A;  1NJI Q;  2JO0 A;  5HV8 A;  1RO2 A;  2I2X B;  2X2B A;  2MF4 A;  2GZJ A;  2PY8 A;  1M6E X;  2L4B A;  1K9M Q;  3CCS P;  3DS4 A;  1RO0 A;  1K8A Q;  2MVU A;  2N50 A;  2GZI A;  2KGA A;  1KLP A;  2PEJ A;  3L9T A;  2KG9 A;  2FAD A;  3IV9 A;  4DG9 A;  1YJW P;  2GYK A;  2Z45 A;  3DPH A;  3CCJ P;  1GPJ A;  1CEI A;  1QTE A;  3G26 A;  5HGN A;  5DCK A;  4QNB A;  2K94 A;  1YIT P;  4XRO A;  2VLN A;  1AYI A;  2VLO A;  3RG6 C;  2FHS C;  3I55 P;  4F37 A;  2ERH A;  1VQO P;  2K5X A;  4XFZ A;  1VQ9 P;  2QA4 P;  3VRL C;  2L22 A;  2L9F A;  1YJN P;  2EG5 A;  1VQK P;  3LRY A;  1W2B O;  2FMM E;  2LPK A;  5BS1 A;  4H2W C;  1A8O A;  5EW5 E;  2FQ2 A;  2LIW A;  2QNW A;  2GZE A;  1Q6B A;  1V2Z A;  4XRQ A;  1KD1 Q;  3B5I A;  3CC2 P;  2KW2 A;  1QVF O;  2GZG A;  1UNK A;  1VHN A;  1ZNV A;  1D1D A;  3EJB A;  3H0D A;  2CQ8 A;  3LMO A;  1Q6A A;  2KGE A;  2PEO A;  2KG6 A;  4PWV B;  1K98 A;  3BUL A;  1KC8 Q;  4HKG A;  1VQP P;  2CG5 B;  3CXC O;  3CCQ P;  2PEN A;  1UJZ A;  2KOQ A;  2QEX P;  1VQM P;  2JYG A;  1QRJ A;  2P9X A;  3CC7 P;  3IVA A;  3CCL P;  2PEM A;  1IUQ A;  3GJN A;  2J6Z A;  2EHS A;  2M8L A;  2M8P A;  3NTE A;  3CPW O;  5JPA A;  1X3O A;  3BJD A;  2N98 A;  3GZL A;  5CZD B;  2PBI A;  2FVE A;  4M0M A;  3U43 A;  1SV1 A;  4R0M A;  2VSQ A;  1HQB A;  3MGE A;  3DS2 A;  2J6Y A;  1GXG A;  1FR2 A;  3GKL C;  3G1G A;  4MRT C;  2OTL P;  5HVC A;  1M74 A; 
#chains in the Genus database with same CATH homology
 3I55 P;  2Z44 A;  3G28 A;  1BAJ A;  2PEQ A;  2OAR A;  1Q7Y Q;  3DTJ A;  1YIJ P;  3Q20 A;  1VQ8 P;  4U0F A;  1EIA A;  1VQO P;  1YHQ P;  1AUM A;  4XFZ A;  3CCM P;  1VQ5 P;  4U0A A;  1VQ9 P;  2BHV A;  3CCE P;  1N8R Q;  3DS3 A;  1KQS O;  3CME P;  2QA4 P;  3VRL C;  1VQ4 P;  1YJN P;  1E6J P;  4COP A;  2EIA A;  2CWO A;  3DS0 A;  5F2K A;  2EG5 A;  1VQK P;  3I56 P;  3LRY A;  1W2B O;  2BUO A;  2EFJ A;  1VQ7 P;  3G1I A;  5F2O A;  2FMM E;  1UTU A;  2OTJ P;  1QVG O;  1M1K Q;  4XFY A;  5BS1 A;  4U0B A;  4PH1 A;  3G4S P;  1A8O A;  3CMA P;  5HGL A;  3CC7 P;  1K30 A;  4COC A;  4U0C A;  4XRQ A;  3CCR P;  3B5I A;  1KD1 Q;  1VQN P;  1Q86 Q;  3H20 A;  3M1M A;  1VQ6 P;  5HGO A;  2DGY A;  3G71 P;  4U0E A;  3G21 A;  3CC2 P;  1QVF O;  2XV6 A;  1M90 Q;  5BS2 A;  3WBH A;  1A43 A;  3H47 A;  4M0I A;  2M8N A;  2Z46 A;  3CCU P;  3CC4 P;  2XXM A;  1Q81 Q;  1D1D A;  2L6E A;  3H4E A;  1VQL P;  3H0D A;  4IPY A;  4GR6 A;  1NJI Q;  2JO0 A;  1RO2 A;  1ZMB A;  2PEK A;  2PEO A;  1KC8 Q;  1VQP P;  3G0V A;  3CXC O;  2PY8 A;  3CCQ P;  2XT1 A;  2PEN A;  3CD6 P;  2QEX P;  1M6E X;  1VQM P;  2JYG A;  1QRJ A;  2P9X A;  1YJ9 P;  1K9M Q;  2E1M A;  3CCS P;  2PEM A;  3DS4 A;  3G29 A;  3CCL P;  1RO0 A;  1IUQ A;  2ONT A;  3DS1 A;  1K8A Q;  3OW2 O;  2M8L A;  5I4T G;  2M8P A;  3NTE A;  3CPW O;  3DS5 A;  5JPA A;  2PEJ A;  1YI2 P;  3HZQ A;  2PEI A;  2PBI A;  4M0M A;  3L9T A;  1S72 P;  3HYB A;  2JYL A;  4GR2 A;  1YJW P;  3P05 A;  1RNI A;  2KOD A;  1EOQ A;  3MGE A;  4PH0 A;  2Z45 A;  3DPH A;  3CCJ P;  3DS2 A;  3CCV P;  4WYM A;  4XFX A;  1UZ3 A;  3E2D A;  3G26 A;  5HGN A;  5DCK A;  4QNB A;  4U0D A;  2LF4 A;  4X8Q A;  1K73 Q;  5F2N A;  1M6N A;  1YIT P;  4XRO A;  3G1G A;  5HGM A;  3G6E P;  1Q82 Q;  2OTL P;  1JJ2 O;  3RG6 C;  1M74 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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