3M1MA

Crystal structure of the primase-polymerase from sulfolobus islandicus
Total Genus 121
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
121
sequence length
331
structure length
320
Chain Sequence
SSERIRYAKWFLEHGFNIIPIDPESKKPVLKEWQKYSHEMPSDEEKQRFLKMIEEGYNYAIPGGQKGLVILDFESKEKLKAWIGESALEELCRKTLCTNTVHGGIHIYVLSNDIPPHKINPLFEENGKGIIDLQSYNSYVLGLGSCVNHLHCTTDKCPWKEQNYTTCYTLYNELKEISKVDLKSLLRFLAEKGKRLGITLSKTAKEWLEGEELRKELVKRDSGKPVEKIKEEICTKSPPKLIKEIICENKTYADVNIDRSRGDWHVILYLMKHGVTDPDKILELLPRDSKAKENEKWNTQKYFVITLSKAWSVVKKYLEA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The archaeo-eukaryotic primase of plasmid pRN1 requires a helix bundle domain for faithful primer synthesis
pubmed doi rcsb
molecule tags Replication
source organism Sulfolobus islandicus
molecule keywords ORF904
total genus 121
structure length 320
sequence length 331
ec nomenclature
pdb deposition date 2010-03-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09250 Prim-Pol Bifunctional DNA primase/polymerase, N-terminal
A PF13010 pRN1_helical Primase helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.130 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A 3m1mA01
1.10.1240.50 Mainly Alpha Orthogonal Bundle Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 3m1mA03
3.30.2250.10 Alpha Beta 2-Layer Sandwich Prim-pol fold Bifunctional DNA primase/polymerase domain 3m1mA02
1RO0A 1RO2A 3H20A 3M1MA 1RNIA
chains in the Genus database with same CATH superfamily
1GXGA 2N6ZA 3G6EP 2LOLA 1CEIA 3M1MA 2FVFA 4XFXA 5EJDA 3DTJA 4M0MA 5F2KA 4IPYA 2AVAA 1DNYA 2GYKA 1M1KQ 3LRYA 3I55P 1R8JA 4DG9A 5C8DA 4MRTC 2XT1A 1E0HA 2KW2A 2GZEA 2LF4A 3G1GA 1RO2A 2GDXA 2KOSA 3G28A 3CC2P 3DS1A 4HH3C 2KORA 2N5HA 3CPWO 2AFDA 1M6EX 2K0YA 1QSAA 5KP8B 4H2YC 1ZMBA 2P9XA 1K8AQ 2FQ2A 2L0QA 1QVFO 5HV8A 1RNIA 5F2NA 2CNRA 2LIUA 1YI2P 3BULA 5EW5E 2GDYA 3DS2A 1AF8A 2K0DX 3HYBA 2OTLP 2LKIA 1IMPA 2QA4P 2EFJA 2MY5A 2GZFA 4XROA 2K2QA 2K5XA 3NTEA 2JBGA 3CXCO 1L0HA 2JU1A 1Q6AA 1QRJA 1VQ7P 1BMTA 2VLQA 2CQ8A 1F80D 3G0VA 2KOQA 2PEIA 2JAZA 3G21A 4U0DA 5KP7B 1BXIA 4NEOA 2AF8A 1VQ4P 3H47A 1V2ZA 3GKLC 2E1MA 1GPJA 2FHSC 1Q6BA 1VQ5P 1EOQA 1D1DA 2KG9A 1FR2A 3G71P 2JB0A 2J6YA 3Q20A 2BHVA 3G4SP 3H20A 4BPHA 2PEOA 2Z44A 1ACPA 3H0DA 2L9FA 1L0IA 1Q86Q 1QVGO 5CZDB 3GZLA 4GR2A 1EIAA 1R5QA 2BUOA 1VQKP 1AUMA 3CD6P 2M8PA 2N6YA 2XZ0D 1A43A 1VQPP 1VQMP 2QNWA 2MF4A 1Q82Q 2EHTA 1UTUA 1X3OA 2PNGA 3B5IA 1RO0A 2N50A 3CC4P 2PY8A 3B4QA 2KGEA 2LL8A 4PWVB 1Z6MA 3IV9A 2K93A 1KD1Q 1UJZA 4G86A 2MD9A 2FQ0A 4PH1A 1YJWP 2PEKA 2EHSA 2KGDA 2X2BA 1AYIA 2K94A 5I4TG 1GXHA 2KG6A 5C5EA 2FVAA 1NQ4A 3EJEA 3H4EA 3HZQA 4CA3A 2KOPA 2OTJP 2GDWA 3CE7A 2KGAA 1W53A 2XXMA 1VQOP 5HGLA 5DCKA 1W2BO 2PBIA 3DS0A 1VQ6P 2JQ4A 4HKGA 3EJDA 4IZ6A 3CCVP 2PEJA 4XRQA 5HVCA 1QTEA 1VQNP 5HGMA 7CEIA 1M90Q 4COPA 2L22A 1T8KA 1NJIQ 3VRLC 1JJ2O 2K92A 4U0EA 2PEMA 1IMQA 2KR5A 3WBHA 2EG5A 1ZNVA 2M5RA 1A8OA 4JGIA 5HGNA 1VHNA 2JO0A 1Q7YQ 3CCMP 4BPGA 3U43A 2Z46A 2QEXP 4X8QA 3BJDA 4COCA 3E2DA 2VLPA 2CG5B 3EJBA 4H2WC 1SV1A 1OR5A 5F2OA 4GR6A 3RG2A 1E6JP 2CWOA 2PEQA 2JU2A 2JGPA 2PENA 4PH0A 3EZXA 2GZGA 2KODA 2WPTA 3DS3A 2XV6A 3IVAA 4R0MA 2ERHA 1IUQA 3L9TA 2K0XA 1BAJA 1N8RQ 2VLOA 1VQLP 5BS2A 1K98A 1SLYA 3CC7P 2JYLA 4WYMA 2FQ1A 1YJNP 2MR7A 3I56P 2ONTA 1M74A 4QNBA 2VSQA 3G26A 3MGEA 1UZ3A 2Z45A 1VQ9P 1YJ9P 3OW2O 3CCJP 2KWLA 3CCQP 4XFZA 2L6EA 1UNKA 3GZMA 2FAEA 2LMLA 1K73Q 5JPAA 1MZ8A 2J6ZA 4HEHA 1YHQP 1KC8Q 3GJNA 4U0AA 2NO8A 2ROQA 2FVEA 5HGOA 2KGCA 3CMEP 3WHPA 1HY8A 2OARA 1VKUA 4U0BA 2FADA 2N5IA 2GZJA 3RG6C 2KG8A 3DS4A 2MVUA 1K30A 2L4BA 2M8LA 4BPFA 4XFYA 3CCEP 3P05A 2DNWA 2JYGA 2DGYA 3G1IA 5KP6B 1KQSO 1SUYA 3CMAP 2M8NA 3CCUP 2LPKA 2VLNA 4QKOA 5BS1A 3LMOA 4U0FA 1KLPA 2MR8A 1EMVA 3G29A 4UHPB 2KOOA 4M0IA 3CCSP 2AFEA 3NY7B 4F37A 1HQBA 2LIWA 2XZ1C 2J70A 2EIAA 4PXHB 1K7YA 2FACA 2GZIA 3DPHA 1K9MQ 3CCLP 2CGQA 2N98A 1S72P 2LTEA 1DV5A 1Q81Q 1VQ8P 1YITP 2FMME 1M6NA 2I2XB 4U0CA 3CCRP 4H2XC 2MVVA 1YIJP 3DS5A
chains in the Genus database with same CATH topology
2PEJA 4XRQA 3G6EP 3CCQP 1VQ4P 4XFZA 2L6EA 3H47A 3M1MA 2E1MA 1VQNP 5HGMA 4XFXA 1VQ5P 3DTJA 4COPA 1M90Q 4M0MA 1EOQA 1NJIQ 1D1DA 1K73Q 3VRLC 5JPAA 5F2KA 1YIJP 1JJ2O 3G71P 4IPYA 3Q20A 2BHVA 4U0EA 2PEMA 3G4SP 1YHQP 1KC8Q 3H20A 2PEOA 2Z44A 3WBHA 2EG5A 4U0AA 1M1KQ 3LRYA 3H0DA 3I55P 1A8OA 1Q86Q 1QVGO 5HGNA 2JO0A 1EIAA 4GR2A 5HGOA 1Q7YQ 3CCMP 2BUOA 1VQKP 3CMEP 2XT1A 1AUMA 2OARA 3CD6P 2M8PA 2Z46A 2QEXP 4X8QA 2LF4A 1A43A 3G1GA 1RO2A 1VQPP 4U0BA 1VQMP 3G28A 3CC2P 4COCA 3DS1A 3E2DA 3RG6C 1Q82Q 3DS4A 3CPWO 1UTUA 1M6EX 3B5IA 5F2OA 1K30A 2M8LA 4XFYA 1RO0A 3CCEP 1ZMBA 3P05A 2P9XA 1K8AQ 3CC4P 4GR6A 2PY8A 1E6JP 2JYGA 2CWOA 2DGYA 3G1IA 1QVFO 2PEQA 1RNIA 1KQSO 1KD1Q 5F2NA 1YI2P 3CMAP 2PENA 4PH1A 4PH0A 2M8NA 3CCUP 5BS1A 2KODA 1YJWP 3DS2A 3DS3A 2XV6A 4U0FA 3HYBA 3CCVP 2OTLP 2PEKA 3G29A 2QA4P 2EFJA 1IUQA 4M0IA 3L9TA 3CCSP 1BAJA 4XROA 5I4TG 1N8RQ 1VQLP 5BS2A 3NTEA 3H4EA 3HZQA 3CXCO 3CC7P 2EIAA 2JYLA 4WYMA 1YJNP 2OTJP 1QRJA 1VQ7P 3DPHA 3I56P 1K9MQ 2ONTA 3CCLP 1M74A 3G0VA 4QNBA 3G26A 2XXMA 1VQOP 1S72P 3MGEA 5HGLA 5DCKA 1UZ3A 2Z45A 1W2BO 1VQ9P 2PEIA 1Q81Q 1VQ8P 1YITP 2FMME 2PBIA 1M6NA 1YJ9P 3DS0A 1VQ6P 4U0CA 3CCRP 3G21A 3OW2O 4U0DA 3CCJP 3DS5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RO0 A;  1RO2 A;  3H20 A;  3M1M A;  1RNI A; 
#chains in the Genus database with same CATH topology
 1GXG A;  2N6Z A;  3G6E P;  2LOL A;  1CEI A;  3M1M A;  2FVF A;  4XFX A;  5EJD A;  3DTJ A;  4M0M A;  5F2K A;  4IPY A;  2AVA A;  1DNY A;  2GYK A;  1M1K Q;  3LRY A;  3I55 P;  1R8J A;  4DG9 A;  5C8D A;  4MRT C;  2XT1 A;  1E0H A;  2KW2 A;  2GZE A;  2LF4 A;  3G1G A;  1RO2 A;  2GDX A;  2KOS A;  3G28 A;  3CC2 P;  3DS1 A;  4HH3 C;  2KOR A;  2N5H A;  3CPW O;  2AFD A;  1M6E X;  2K0Y A;  1QSA A;  5KP8 B;  4H2Y C;  1ZMB A;  2P9X A;  1K8A Q;  2FQ2 A;  2L0Q A;  1QVF O;  5HV8 A;  1RNI A;  5F2N A;  2CNR A;  2LIU A;  1YI2 P;  3BUL A;  5EW5 E;  2GDY A;  3DS2 A;  1AF8 A;  2K0D X;  3HYB A;  2OTL P;  2LKI A;  1IMP A;  2QA4 P;  2EFJ A;  2MY5 A;  2GZF A;  4XRO A;  2K2Q A;  2K5X A;  3NTE A;  2JBG A;  3CXC O;  1L0H A;  2JU1 A;  1Q6A A;  1QRJ A;  1VQ7 P;  1BMT A;  2VLQ A;  2CQ8 A;  1F80 D;  3G0V A;  2KOQ A;  2PEI A;  2JAZ A;  3G21 A;  4U0D A;  5KP7 B;  1BXI A;  4NEO A;  2AF8 A;  1VQ4 P;  3H47 A;  1V2Z A;  3GKL C;  2E1M A;  1GPJ A;  2FHS C;  1Q6B A;  1VQ5 P;  1EOQ A;  1D1D A;  2KG9 A;  1FR2 A;  3G71 P;  2JB0 A;  2J6Y A;  3Q20 A;  2BHV A;  3G4S P;  3H20 A;  4BPH A;  2PEO A;  2Z44 A;  1ACP A;  3H0D A;  2L9F A;  1L0I A;  1Q86 Q;  1QVG O;  5CZD B;  3GZL A;  4GR2 A;  1EIA A;  1R5Q A;  2BUO A;  1VQK P;  1AUM A;  3CD6 P;  2M8P A;  2N6Y A;  2XZ0 D;  1A43 A;  1VQP P;  1VQM P;  2QNW A;  2MF4 A;  1Q82 Q;  2EHT A;  1UTU A;  1X3O A;  2PNG A;  3B5I A;  1RO0 A;  2N50 A;  3CC4 P;  2PY8 A;  3B4Q A;  2KGE A;  2LL8 A;  4PWV B;  1Z6M A;  3IV9 A;  2K93 A;  1KD1 Q;  1UJZ A;  4G86 A;  2MD9 A;  2FQ0 A;  4PH1 A;  1YJW P;  2PEK A;  2EHS A;  2KGD A;  2X2B A;  1AYI A;  2K94 A;  5I4T G;  1GXH A;  2KG6 A;  5C5E A;  2FVA A;  1NQ4 A;  3EJE A;  3H4E A;  3HZQ A;  4CA3 A;  2KOP A;  2OTJ P;  2GDW A;  3CE7 A;  2KGA A;  1W53 A;  2XXM A;  1VQO P;  5HGL A;  5DCK A;  1W2B O;  2PBI A;  3DS0 A;  1VQ6 P;  2JQ4 A;  4HKG A;  3EJD A;  4IZ6 A;  3CCV P;  2PEJ A;  4XRQ A;  5HVC A;  1QTE A;  1VQN P;  5HGM A;  7CEI A;  1M90 Q;  4COP A;  2L22 A;  1T8K A;  1NJI Q;  3VRL C;  1JJ2 O;  2K92 A;  4U0E A;  2PEM A;  1IMQ A;  2KR5 A;  3WBH A;  2EG5 A;  1ZNV A;  2M5R A;  1A8O A;  4JGI A;  5HGN A;  1VHN A;  2JO0 A;  1Q7Y Q;  3CCM P;  4BPG A;  3U43 A;  2Z46 A;  2QEX P;  4X8Q A;  3BJD A;  4COC A;  3E2D A;  2VLP A;  2CG5 B;  3EJB A;  4H2W C;  1SV1 A;  1OR5 A;  5F2O A;  4GR6 A;  3RG2 A;  1E6J P;  2CWO A;  2PEQ A;  2JU2 A;  2JGP A;  2PEN A;  4PH0 A;  3EZX A;  2GZG A;  2KOD A;  2WPT A;  3DS3 A;  2XV6 A;  3IVA A;  4R0M A;  2ERH A;  1IUQ A;  3L9T A;  2K0X A;  1BAJ A;  1N8R Q;  2VLO A;  1VQL P;  5BS2 A;  1K98 A;  1SLY A;  3CC7 P;  2JYL A;  4WYM A;  2FQ1 A;  1YJN P;  2MR7 A;  3I56 P;  2ONT A;  1M74 A;  4QNB A;  2VSQ A;  3G26 A;  3MGE A;  1UZ3 A;  2Z45 A;  1VQ9 P;  1YJ9 P;  3OW2 O;  3CCJ P;  2KWL A;  3CCQ P;  4XFZ A;  2L6E A;  1UNK A;  3GZM A;  2FAE A;  2LML A;  1K73 Q;  5JPA A;  1MZ8 A;  2J6Z A;  4HEH A;  1YHQ P;  1KC8 Q;  3GJN A;  4U0A A;  2NO8 A;  2ROQ A;  2FVE A;  5HGO A;  2KGC A;  3CME P;  3WHP A;  1HY8 A;  2OAR A;  1VKU A;  4U0B A;  2FAD A;  2N5I A;  2GZJ A;  3RG6 C;  2KG8 A;  3DS4 A;  2MVU A;  1K30 A;  2L4B A;  2M8L A;  4BPF A;  4XFY A;  3CCE P;  3P05 A;  2DNW A;  2JYG A;  2DGY A;  3G1I A;  5KP6 B;  1KQS O;  1SUY A;  3CMA P;  2M8N A;  3CCU P;  2LPK A;  2VLN A;  4QKO A;  5BS1 A;  3LMO A;  4U0F A;  1KLP A;  2MR8 A;  1EMV A;  3G29 A;  4UHP B;  2KOO A;  4M0I A;  3CCS P;  2AFE A;  3NY7 B;  4F37 A;  1HQB A;  2LIW A;  2XZ1 C;  2J70 A;  2EIA A;  4PXH B;  1K7Y A;  2FAC A;  2GZI A;  3DPH A;  1K9M Q;  3CCL P;  2CGQ A;  2N98 A;  1S72 P;  2LTE A;  1DV5 A;  1Q81 Q;  1VQ8 P;  1YIT P;  2FMM E;  1M6N A;  2I2X B;  4U0C A;  3CCR P;  4H2X C;  2MVV A;  1YIJ P;  3DS5 A; 
#chains in the Genus database with same CATH homology
 2PEJ A;  4XRQ A;  3G6E P;  3CCQ P;  1VQ4 P;  4XFZ A;  2L6E A;  3H47 A;  3M1M A;  2E1M A;  1VQN P;  5HGM A;  4XFX A;  1VQ5 P;  3DTJ A;  4COP A;  1M90 Q;  4M0M A;  1EOQ A;  1NJI Q;  1D1D A;  1K73 Q;  3VRL C;  5JPA A;  5F2K A;  1YIJ P;  1JJ2 O;  3G71 P;  4IPY A;  3Q20 A;  2BHV A;  4U0E A;  2PEM A;  3G4S P;  1YHQ P;  1KC8 Q;  3H20 A;  2PEO A;  2Z44 A;  3WBH A;  2EG5 A;  4U0A A;  1M1K Q;  3LRY A;  3H0D A;  3I55 P;  1A8O A;  1Q86 Q;  1QVG O;  5HGN A;  2JO0 A;  1EIA A;  4GR2 A;  5HGO A;  1Q7Y Q;  3CCM P;  2BUO A;  1VQK P;  3CME P;  2XT1 A;  1AUM A;  2OAR A;  3CD6 P;  2M8P A;  2Z46 A;  2QEX P;  4X8Q A;  2LF4 A;  1A43 A;  3G1G A;  1RO2 A;  1VQP P;  4U0B A;  1VQM P;  3G28 A;  3CC2 P;  4COC A;  3DS1 A;  3E2D A;  3RG6 C;  1Q82 Q;  3DS4 A;  3CPW O;  1UTU A;  1M6E X;  3B5I A;  5F2O A;  1K30 A;  2M8L A;  4XFY A;  1RO0 A;  3CCE P;  1ZMB A;  3P05 A;  2P9X A;  1K8A Q;  3CC4 P;  4GR6 A;  2PY8 A;  1E6J P;  2JYG A;  2CWO A;  2DGY A;  3G1I A;  1QVF O;  2PEQ A;  1RNI A;  1KQS O;  1KD1 Q;  5F2N A;  1YI2 P;  3CMA P;  2PEN A;  4PH1 A;  4PH0 A;  2M8N A;  3CCU P;  5BS1 A;  2KOD A;  1YJW P;  3DS2 A;  3DS3 A;  2XV6 A;  4U0F A;  3HYB A;  3CCV P;  2OTL P;  2PEK A;  3G29 A;  2QA4 P;  2EFJ A;  1IUQ A;  4M0I A;  3L9T A;  3CCS P;  1BAJ A;  4XRO A;  5I4T G;  1N8R Q;  1VQL P;  5BS2 A;  3NTE A;  3H4E A;  3HZQ A;  3CXC O;  3CC7 P;  2EIA A;  2JYL A;  4WYM A;  1YJN P;  2OTJ P;  1QRJ A;  1VQ7 P;  3DPH A;  3I56 P;  1K9M Q;  2ONT A;  3CCL P;  1M74 A;  3G0V A;  4QNB A;  3G26 A;  2XXM A;  1VQO P;  1S72 P;  3MGE A;  5HGL A;  5DCK A;  1UZ3 A;  2Z45 A;  1W2B O;  1VQ9 P;  2PEI A;  1Q81 Q;  1VQ8 P;  1YIT P;  2FMM E;  2PBI A;  1M6N A;  1YJ9 P;  3DS0 A;  1VQ6 P;  4U0C A;  3CCR P;  3G21 A;  3OW2 O;  4U0D A;  3CCJ P;  3DS5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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