1DCHA

Crystal structure of dcoh, a bifunctional, protein-binding transcription coactivator
Total Genus 31
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
31
sequence length
99
structure length
99
Chain Sequence
HRLSAEERDQLLPNLRAVGWNELEGRDAIFKQFHFKDFNRAFGFMTRVALQAEKLDHHPEWFNVYNKVHITLSTHECAGLSERDINLASFIEQVAVSMT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of DCoH, a bifunctional, protein-binding transcriptional coactivator.
pubmed rcsb
molecule tags Transcriptional stimulator,dimerization
source organism Rattus norvegicus
molecule keywords DCOH (DIMERIZATION COFACTOR OF HNF-1)
total genus 31
structure length 99
sequence length 99
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 4.2.1.96: 4a-hydroxytetrahydrobiopterin dehydratase.
pdb deposition date 1995-01-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01329 Pterin_4a Pterin 4 alpha carbinolamine dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1360.20 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 Transcriptional coactivator/pterin dehydratase 1dchA00
2V6SA 1USMA 2V6TA 1USOA 2EBBA 1F93A 1DCHA 3HXAA 4WILA 1RU0A 4C45A 1DCOA 4LOWA 2V6UA 1DCPA 3JSTA
chains in the Genus database with same CATH superfamily
4DDQA 4BY1K 4A3JC 1JOEA 2GAHC 1I6VA 1O25A 3GTQA 2O5IA 5IP9K 4A3FC 4A3DC 2B63A 4AYBL 4GZYA 1VRQC 4C2MK 2NVYK 3T02A 2NVQC 1F7VA 3M4OC 4BY7C 1O24A 4XSXA 3CQZK 4M1XA 2JA8C 3PO3K 4X6AK 1XXCA 4G7ZA 2GSUA 3H3VD 2JA5C 3HOZK 1IW7A 2A6EA 4A3IC 3HOVC 3GEEA 3AD7C 5D4DA 3H0GC 4C3IK 1O2FB 4C45A 4QIWL 4KMDA 1TWHK 1XXAA 3IPJA 3S0XA 3G4CA 1JQWA 4YG2A 3RZDK 4BBRC 3GTPK 2Y3PA 3GEHA 4BY1C 1WOOA 5CHPA 2R7ZK 3OEPA 5JVOA 4GTCA 5IP9C 3S16C 3GTLK 2E2IK 1EH1A 3Q3QA 4LK1A 5TMFA 2NVYC 3GTKA 1B4AA 2XCOA 3CQZC 2BE5A 3HOWC 2P5MA 5IOTA 3GTJK 3LAPA 3S2DK 5EGHA 4A3CC 3GEIA 1R9TA 4GTBA 3V4GA 1TWAK 3HKZD 4A3BK 4G7HA 1B4BA 1O29A 4C3IC 3DXJA 1IL2A 1IE0A 5IYBC 1WSVA 2PA8D 4WILA 2VUMC 3A8KA 1IS1A 5M3MK 4KATA 4OIQA 5C4XK 4BKWA 3I4MK 1HI9A 3FOEA 1TWFK 4KC6A 1Y1WK 1PJ6A 1UV7A 4GFQA 2ZUEA 3GTLC 2CFAA 4GTFA 1WCMC 4A3JK 1O2AA 1K83A 3HOUK 4P9SA 4A3FK 3S2DC 4A3DK 1BGWA 4YFNA 2JA7K 1WORA 2NVQK 5HL8A 1TWAC 3TFIA 2JA8K 4A3BC 4LLGA 4WJ3M 3HOYC 3TTGA 4RMFA 3T00A 2A6HA 4LOWA 1DCPA 3S1NC 2YU9A 2JA5K 1XXBA 4A3IK 5FJ8K 3HOVK 2ZFZA 1YCLA 1TWGA 3GTGC 2Y0SL 1ZVUA 3H0GK 4KMHA 2W7VA 1L0WA 5L46A 1TWFC 1XZPA 4KN4A 1Y1WC 4JK1A 2GSOA 2P8TA 4BBRK 2R93A 2R92A 1USOA 2WAQD 2XCRB 4C3JC 3NUHA 4KB4A 2PMZD 1IBAA 3HOUC 2RGRA 1O2BA 1F93A 3GTOA 3S16K 1WQHA 2JA7C 4OIOA 4XLPA 2EBBA 3HOWK 1ZBSA 3GTQC 2NVTK 4A3CK 3I4NK 2ZUFA 2B63C 3VA7A 1EK8A 1KQ4A 2O5JA 3N3YA 4PAAA 3GTKK 4A3GC 1WOSA 2GAGC 2JA6A 5IYBK 4BLBA 2VUMK 4BBSC 4Y7NK 2GSNA 1ZXOA 1R9TK 4KMUA 1O28A 1O27A 1WQFA 2CW0A 3S2HC 4NOIA 5IYDC 5TJ3A 3FKIA 1Y1VA 1IQ0A 1O26A 1PJ5A 3G4AA 3S14C 1VJEA 1BJTA 1WCMK 5IOSA 3LPXA 4FM9A 2FQOA 5E68A 3PO2K 2A68A 3S15C 3H3VL 1XPPA 2NVTC 3I4NC 4YFXA 3AH5A 1INNA 4G0UA 3HOYK 3GTKC 3GTMA 4P5AA 4ILDA 2V6UA 3S1NK 3K7AK 4MQ9A 1TWCA 4Y7NC 3N0BA 5IOQA 3GTGK 4O2DA 1R9TC 1J6VA 4Y52K 4KN7A 1TWHA 3SZYA 3ADAC 2V6SA 1J6XA 1DCHA 4QJVA 1HQMA 4LQYA 3GTPA 5M3FK 1WOPA 2RH6A 4XSZA 2D6FC 4C3JK 3FHZA 5FLMK 2PHCB 1BS2A 1WQGA 3OPFA 4FZBA 4KARA 4PABA 3HOXK 3PO2C 5C44C 2R7ZA 1VH2A 3S1MC 2E2IA 3FOFA 1I50A 3HKZL 4YFKA 2V6TA 3QX3A 2E2HA 2PPBA 4XCHA 3GTJA 1K83C 3GTQK 3L4KA 1ZYRA 3HXAA 2PA8L 3BP3A 3K7AC 2B63K 3A8IA 3RZOK 4A3GK 1SFOA 4P5BA 4LR2A 4Y52C 1YNJA 4GTLA 3AQOA 2YU9C 4BBSK 4AYBD 4A3KK 1ZQ1C 1TWGC 5C4JK 3AD9C 3S2HK 2NVXA 4OINA 4BXXK 4Q4ZA 5IYDK 5IP7K 5FLMC 2JA6K 3N0CA 3HOXC 3TFHA 3L4JA 3S14K 2A69A 4A3MC 2R93C 2XCQA 2R92C 4A3EC 4A93C 2WB1D 3CAGA 5IYCC 2CFAB 4QIWD 3GSIA 3FKIK 1I6HC 1Y1VK 3S1QC 3S15K 3JSTA 1F9NA 3AD8C 3GTOC 5C3EK 4MEXA 1JVIA 1YNNA 3RZOC 2JA5A 3T01A 1DD5A 1EI6A 1XZQA 2KWAA 4A3KC 4GTDA 3H0GA 1V5VA 4GTAA 4KM9A 2WAQL 5C4JC 3TFJA 3GTMK 1YX2A 1G51A 3S1RK 2PMZL 4BXXC 1WIHA 1I3QA 5IP7C 2JA6C 1TWCK 1SMYA 3WODA 1AB4A 2E2JC 1XZPB 5M5XK 4AH6A 2WB1L 4G0WA 3MMLB 4GT9A 1I3QC 3FKIC 4KB2A 5C44K 1Y1VC 4A3LK 3S1MK 2NVYA 1USMA 5C3EC 3M3YK 3CQZA 4GTEA 1J6WA 1K83K 5IORA 4LK0A 4C2MC 1I50K 4OIPA 3EQLA 4KM8A 2E2HK 1PJ7A 3PO3C 4WJ4A 3GTMC 3S1RC 4KASA 1ISEA 4X6AC 1X31C 5CJ9A 5JFEA 1VLOA 2VUMA 4KDDA 2YU9K 3LAJA 3HOZC 4KAWX 1TWCC 1TWGK 1VGXA 3S17K 1XZQB 1SFOK 4MEYA 3AQPA 4OIRA 3BP8C 1TWHC 2JH3A 4XLNA 1EQRA 4C3HK 3BUEA 4A3LC 3GTLA 1RU0A 1WSRA 3RZDC 4A3MK 3GTPC 2R93K 2Y0SD 2R92K 4A3EK 1WCMA 4A93K 2NVXK 5IYCK 3M3YC 3GDZA 4J3NA 1I6HK 3S1QK 1J98A 2R7ZC 3SZZA 2E2IC 3GTOK 5TMCA 3A8JA 4G7OA 1TWAA 1I50C 3GIRA 1F7UA 1EFWA 4ZH4A 2E2HC 3OREA 3GTJC 3GTGA 3M4OK 4BY7K 5M5WK 1C0AA 1GE9A 4G0VA 3S17C 4LJZA 1SFOC 1TWFA 4BLAA 1Y1WA 3ERED 4C3HC 5M5YK 2E2JK 5C4XC 4QJVB 1BDFA 2NVXC 3I4MC 1I3QK 4KMAA 5EGEA 2JA7A 1DCOA 4Q5SA 2FQTA
chains in the Genus database with same CATH topology
2V6SA 1USMA 2V6TA 1USOA 2EBBA 1F93A 1DCHA 3HXAA 4WILA 1RU0A 4C45A 1DCOA 4LOWA 2V6UA 1DCPA 3JSTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2V6S A;  1USM A;  2V6T A;  1USO A;  2EBB A;  1F93 A;  1DCH A;  3HXA A;  4WIL A;  1RU0 A;  4C45 A;  1DCO A;  4LOW A;  2V6U A;  1DCP A;  3JST A; 
#chains in the Genus database with same CATH topology
 4DDQ A;  4BY1 K;  4A3J C;  1JOE A;  2GAH C;  1I6V A;  1O25 A;  3GTQ A;  2O5I A;  5IP9 K;  4A3F C;  4A3D C;  2B63 A;  4AYB L;  4GZY A;  1VRQ C;  4C2M K;  2NVY K;  3T02 A;  2NVQ C;  1F7V A;  3M4O C;  4BY7 C;  1O24 A;  4XSX A;  3CQZ K;  4M1X A;  2JA8 C;  3PO3 K;  4X6A K;  1XXC A;  4G7Z A;  2GSU A;  3H3V D;  2JA5 C;  3HOZ K;  1IW7 A;  2A6E A;  4A3I C;  3HOV C;  3GEE A;  3AD7 C;  5D4D A;  3H0G C;  4C3I K;  1O2F B;  4C45 A;  4QIW L;  4KMD A;  1TWH K;  1XXA A;  3IPJ A;  3S0X A;  3G4C A;  1JQW A;  4YG2 A;  3RZD K;  4BBR C;  3GTP K;  2Y3P A;  3GEH A;  4BY1 C;  1WOO A;  5CHP A;  2R7Z K;  3OEP A;  5JVO A;  4GTC A;  5IP9 C;  3S16 C;  3GTL K;  2E2I K;  1EH1 A;  3Q3Q A;  4LK1 A;  5TMF A;  2NVY C;  3GTK A;  1B4A A;  2XCO A;  3CQZ C;  2BE5 A;  3HOW C;  2P5M A;  5IOT A;  3GTJ K;  3LAP A;  3S2D K;  5EGH A;  4A3C C;  3GEI A;  1R9T A;  4GTB A;  3V4G A;  1TWA K;  3HKZ D;  4A3B K;  4G7H A;  1B4B A;  1O29 A;  4C3I C;  3DXJ A;  1IL2 A;  1IE0 A;  5IYB C;  1WSV A;  2PA8 D;  4WIL A;  2VUM C;  3A8K A;  1IS1 A;  5M3M K;  4KAT A;  4OIQ A;  5C4X K;  4BKW A;  3I4M K;  1HI9 A;  3FOE A;  1TWF K;  4KC6 A;  1Y1W K;  1PJ6 A;  1UV7 A;  4GFQ A;  2ZUE A;  3GTL C;  2CFA A;  4GTF A;  1WCM C;  4A3J K;  1O2A A;  1K83 A;  3HOU K;  4P9S A;  4A3F K;  3S2D C;  4A3D K;  1BGW A;  4YFN A;  2JA7 K;  1WOR A;  2NVQ K;  5HL8 A;  1TWA C;  3TFI A;  2JA8 K;  4A3B C;  4LLG A;  4WJ3 M;  3HOY C;  3TTG A;  4RMF A;  3T00 A;  2A6H A;  4LOW A;  1DCP A;  3S1N C;  2YU9 A;  2JA5 K;  1XXB A;  4A3I K;  5FJ8 K;  3HOV K;  2ZFZ A;  1YCL A;  1TWG A;  3GTG C;  2Y0S L;  1ZVU A;  3H0G K;  4KMH A;  2W7V A;  1L0W A;  5L46 A;  1TWF C;  1XZP A;  4KN4 A;  1Y1W C;  4JK1 A;  2GSO A;  2P8T A;  4BBR K;  2R93 A;  2R92 A;  1USO A;  2WAQ D;  2XCR B;  4C3J C;  3NUH A;  4KB4 A;  2PMZ D;  1IBA A;  3HOU C;  2RGR A;  1O2B A;  1F93 A;  3GTO A;  3S16 K;  1WQH A;  2JA7 C;  4OIO A;  4XLP A;  2EBB A;  3HOW K;  1ZBS A;  3GTQ C;  2NVT K;  4A3C K;  3I4N K;  2ZUF A;  2B63 C;  3VA7 A;  1EK8 A;  1KQ4 A;  2O5J A;  3N3Y A;  4PAA A;  3GTK K;  4A3G C;  1WOS A;  2GAG C;  2JA6 A;  5IYB K;  4BLB A;  2VUM K;  4BBS C;  4Y7N K;  2GSN A;  1ZXO A;  1R9T K;  4KMU A;  1O28 A;  1O27 A;  1WQF A;  2CW0 A;  3S2H C;  4NOI A;  5IYD C;  5TJ3 A;  3FKI A;  1Y1V A;  1IQ0 A;  1O26 A;  1PJ5 A;  3G4A A;  3S14 C;  1VJE A;  1BJT A;  1WCM K;  5IOS A;  3LPX A;  4FM9 A;  2FQO A;  5E68 A;  3PO2 K;  2A68 A;  3S15 C;  3H3V L;  1XPP A;  2NVT C;  3I4N C;  4YFX A;  3AH5 A;  1INN A;  4G0U A;  3HOY K;  3GTK C;  3GTM A;  4P5A A;  4ILD A;  2V6U A;  3S1N K;  3K7A K;  4MQ9 A;  1TWC A;  4Y7N C;  3N0B A;  5IOQ A;  3GTG K;  4O2D A;  1R9T C;  1J6V A;  4Y52 K;  4KN7 A;  1TWH A;  3SZY A;  3ADA C;  2V6S A;  1J6X A;  1DCH A;  4QJV A;  1HQM A;  4LQY A;  3GTP A;  5M3F K;  1WOP A;  2RH6 A;  4XSZ A;  2D6F C;  4C3J K;  3FHZ A;  5FLM K;  2PHC B;  1BS2 A;  1WQG A;  3OPF A;  4FZB A;  4KAR A;  4PAB A;  3HOX K;  3PO2 C;  5C44 C;  2R7Z A;  1VH2 A;  3S1M C;  2E2I A;  3FOF A;  1I50 A;  3HKZ L;  4YFK A;  2V6T A;  3QX3 A;  2E2H A;  2PPB A;  4XCH A;  3GTJ A;  1K83 C;  3GTQ K;  3L4K A;  1ZYR A;  3HXA A;  2PA8 L;  3BP3 A;  3K7A C;  2B63 K;  3A8I A;  3RZO K;  4A3G K;  1SFO A;  4P5B A;  4LR2 A;  4Y52 C;  1YNJ A;  4GTL A;  3AQO A;  2YU9 C;  4BBS K;  4AYB D;  4A3K K;  1ZQ1 C;  1TWG C;  5C4J K;  3AD9 C;  3S2H K;  2NVX A;  4OIN A;  4BXX K;  4Q4Z A;  5IYD K;  5IP7 K;  5FLM C;  2JA6 K;  3N0C A;  3HOX C;  3TFH A;  3L4J A;  3S14 K;  2A69 A;  4A3M C;  2R93 C;  2XCQ A;  2R92 C;  4A3E C;  4A93 C;  2WB1 D;  3CAG A;  5IYC C;  2CFA B;  4QIW D;  3GSI A;  3FKI K;  1I6H C;  1Y1V K;  3S1Q C;  3S15 K;  3JST A;  1F9N A;  3AD8 C;  3GTO C;  5C3E K;  4MEX A;  1JVI A;  1YNN A;  3RZO C;  2JA5 A;  3T01 A;  1DD5 A;  1EI6 A;  1XZQ A;  2KWA A;  4A3K C;  4GTD A;  3H0G A;  1V5V A;  4GTA A;  4KM9 A;  2WAQ L;  5C4J C;  3TFJ A;  3GTM K;  1YX2 A;  1G51 A;  3S1R K;  2PMZ L;  4BXX C;  1WIH A;  1I3Q A;  5IP7 C;  2JA6 C;  1TWC K;  1SMY A;  3WOD A;  1AB4 A;  2E2J C;  1XZP B;  5M5X K;  4AH6 A;  2WB1 L;  4G0W A;  3MML B;  4GT9 A;  1I3Q C;  3FKI C;  4KB2 A;  5C44 K;  1Y1V C;  4A3L K;  3S1M K;  2NVY A;  1USM A;  5C3E C;  3M3Y K;  3CQZ A;  4GTE A;  1J6W A;  1K83 K;  5IOR A;  4LK0 A;  4C2M C;  1I50 K;  4OIP A;  3EQL A;  4KM8 A;  2E2H K;  1PJ7 A;  3PO3 C;  4WJ4 A;  3GTM C;  3S1R C;  4KAS A;  1ISE A;  4X6A C;  1X31 C;  5CJ9 A;  5JFE A;  1VLO A;  2VUM A;  4KDD A;  2YU9 K;  3LAJ A;  3HOZ C;  4KAW X;  1TWC C;  1TWG K;  1VGX A;  3S17 K;  1XZQ B;  1SFO K;  4MEY A;  3AQP A;  4OIR A;  3BP8 C;  1TWH C;  2JH3 A;  4XLN A;  1EQR A;  4C3H K;  3BUE A;  4A3L C;  3GTL A;  1RU0 A;  1WSR A;  3RZD C;  4A3M K;  3GTP C;  2R93 K;  2Y0S D;  2R92 K;  4A3E K;  1WCM A;  4A93 K;  2NVX K;  5IYC K;  3M3Y C;  3GDZ A;  4J3N A;  1I6H K;  3S1Q K;  1J98 A;  2R7Z C;  3SZZ A;  2E2I C;  3GTO K;  5TMC A;  3A8J A;  4G7O A;  1TWA A;  1I50 C;  3GIR A;  1F7U A;  1EFW A;  4ZH4 A;  2E2H C;  3ORE A;  3GTJ C;  3GTG A;  3M4O K;  4BY7 K;  5M5W K;  1C0A A;  1GE9 A;  4G0V A;  3S17 C;  4LJZ A;  1SFO C;  1TWF A;  4BLA A;  1Y1W A;  3ERE D;  4C3H C;  5M5Y K;  2E2J K;  5C4X C;  4QJV B;  1BDF A;  2NVX C;  3I4M C;  1I3Q K;  4KMA A;  5EGE A;  2JA7 A;  1DCO A;  4Q5S A;  2FQT A; 
#chains in the Genus database with same CATH homology
 2V6S A;  1USM A;  2V6T A;  1USO A;  2EBB A;  1F93 A;  1DCH A;  3HXA A;  4WIL A;  1RU0 A;  4C45 A;  1DCO A;  4LOW A;  2V6U A;  1DCP A;  3JST A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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