1DCOA

Dcoh, a bifunctional protein-binding transcriptional coactivator
Total Genus 31
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
31
sequence length
99
structure length
99
Chain Sequence
HRLSAEERDQLLPNLRAVGWNELEGRDAIFKQFHFKDFNRAFGFMTRVALQAEKLDHHPEWFNVYNKVHITLSTHECAGLSERDINLASFIEQVAVSMT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title High-resolution structures of the bifunctional enzyme and transcriptional coactivator DCoH and its complex with a product analogue.
pubmed rcsb
molecule tags Transcriptional stimulator
source organism Rattus norvegicus
molecule keywords DCOH
total genus 31
structure length 99
sequence length 99
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 4.2.1.96: 4a-hydroxytetrahydrobiopterin dehydratase.
pdb deposition date 1996-05-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01329 Pterin_4a Pterin 4 alpha carbinolamine dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1360.20 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 Transcriptional coactivator/pterin dehydratase 1dcoA00
2V6UA 1USOA 1USMA 1F93A 2V6TA 1DCPA 3HXAA 2V6SA 4LOWA 4WILA 1DCOA 1DCHA 1RU0A 2EBBA 3JSTA 4C45A
chains in the Genus database with same CATH superfamily
2A6HA 2V6UA 2BE5A 3HKZD 3FKIA 3HOVC 4A3CK 1WOSA 4A3MC 4BBSK 3AD8C 1B4BA 1DCOA 5FLMC 1IW7A 2ZUFA 3I4MK 2NVYK 2R92A 5IYDC 4A3GC 3T02A 2RH6A 2RGRA 2JA6K 3CQZA 3OREA 2B63A 3G4CA 1F93A 4KM8A 3HOXK 3GIRA 3GTKA 4BY1K 2GSNA 3S1QK 3H3VL 2Y3PA 1TWAC 3HOWC 3HXAA 3N3YA 3GTOC 1TWFK 1SFOK 3PO3K 4BLBA 3H3VD 1TWHA 4LK1A 1JVIA 4A3CC 4BBSC 3BP3A 4XSXA 4GTBA 1YNNA 4C3JC 3S17C 4YFNA 3I4MC 3HOZC 1WSRA 1Y1VC 1O25A 2B63K 1B4AA 5IOSA 2JA6C 3GTKK 2CFAB 5M5XK 3HOXC 4BY1C 4BBRC 4C3HC 1WCMA 2PPBA 3H0GA 3DXJA 3AQOA 3FKIC 3TTGA 3GTLA 1UV7A 1I3QA 3PO3C 1ZXOA 2JA7A 1I6HK 2PHCB 4WILA 2P5MA 5JVOA 1TWGA 2NVQC 4KAWX 4P9SA 2R92C 3S2HC 2WAQL 1R9TA 3FOEA 2ZFZA 3NUHA 5M3MK 5IORA 1USOA 2KWAA 3CQZC 2WAQD 3SZZA 4G7ZA 2B63C 3S2DK 3BUEA 3GTKC 2VUMA 3GDZA 2V6SA 4BLAA 3H0GK 3S15K 4O2DA 5TMCA 1WORA 3GTLK 1I3QK 1BDFA 4JK1A 3RZOK 4A93C 1TWHC 4KASA 3A8KA 4DDQA 1TWCA 1TWGK 3OPFA 4KMHA 3GTJK 4BXXK 2R93A 1R9TK 1J98A 2D6FC 1BJTA 3ERED 4GT9A 1WIHA 3HOUK 1WQGA 4AH6A 3GTOA 4BY7C 3HOVK 2Y0SL 1DCHA 4A3MK 4GFQA 1WCMC 1YX2A 5IYCC 5CJ9A 3H0GC 3GEIA 3S15C 5FLMK 2CFAA 1I3QC 1TWCK 2Y0SD 4MEYA 3HOYC 2JA7C 3RZOC 3GTQA 3GSIA 5IYDK 2R93K 1TWGC 2W7VA 2XCQA 4A3LC 4XLNA 3VA7A 5C44C 1R9TC 3A8JA 3GTMA 3L4JA 1TWAK 2ZUEA 3GTOK 2VUMC 3HOUC 3A8IA 3L4KA 1O2FB 4KMAA 1WOPA 1EI6A 5IOTA 1VJEA 3T00A 4C3JK 4X6AK 2FQOA 3S17K 1WOOA 1TWCC 1PJ6A 3HOZK 1Y1VK 3AD7C 1J6XA 2R93C 1XXBA 3LAPA 4XSZA 4AYBD 1ZBSA 4BBRK 4KATA 1IQ0A 2XCOA 4C3HK 1O2AA 1F7VA 1PJ7A 3FKIK 4P5BA 3IPJA 1USMA 4GZYA 2E2JC 1O27A 2NVQK 1Y1WA 1KQ4A 4C45A 4FZBA 5FJ8K 2E2IA 2R92K 3GTQC 3S2HK 3T01A 2WB1L 4X6AC 1VLOA 2JA5A 3LAJA 2PMZL 4KN4A 3MMLB 3FHZA 3CQZK 2GAHC 3GTMC 2WB1D 3GEEA 4QJVA 2O5IA 1WQFA 1VH2A 4MQ9A 2PMZD 3BP8C 2PA8D 1INNA 4A3JC 5JFEA 4A93K 1TWHK 4PABA 1SMYA 1XXCA 1Y1WK 2E2IK 4G7HA 3WODA 4A3DC 4KMUA 1G51A 4NOIA 1EK8A 1XZQB 5HL8A 1O28A 1BGWA 3OEPA 4QIWL 4RMFA 1I50A 4BY7K 1WCMK 4QIWD 4C3IC 5IYCK 1VGXA 4KN7A 4XLPA 1F7UA 5EGEA 1ZQ1C 3HOYK 2JA7K 3S16C 1VRQC 3QX3A 4OINA 3S14K 1DD5A 3S1NK 1XZPB 2V6TA 3ADAC 3N0CA 1Y1WC 2NVTC 4A3LK 2JA8K 2E2IC 3AD9C 3LPXA 5C44K 3TFHA 2A6EA 1O24A 2JA5C 1WSVA 5C4XK 1V5VA 3I4NC 3GTPA 1X31C 4A3BC 4Y7NC 4GTEA 4A3EK 4G7OA 4G0UA 1YCLA 3K7AC 2VUMK 4YFKA 2XCRB 4KC6A 4OIOA 4BKWA 4G0WA 4GTCA 4WJ3M 5TJ3A 5E68A 3S14C 2NVXA 3S1NC 5M3FK 2JA8C 5D4DA 4KM9A 1EH1A 5IP7C 4A3FC 5C4XC 3S0XA 4KMDA 1IL2A 2YU9A 4A3EC 4OIRA 1I50C 4MEXA 4LLGA 4C2MC 1XXAA 3TFJA 1K83A 4OIQA 2E2JK 1JOEA 2FQTA 2NVYA 3GTQK 4KARA 1DCPA 2NVXK 4XCHA 4AYBL 1ISEA 2EBBA 4GTDA 3GTMK 1PJ5A 1O26A 4GTLA 3GTPC 3M3YK 1XZPA 2YU9K 4KDDA 4A3JK 4GTFA 1C0AA 1TWFA 1SFOA 3M4OC 1K83K 3Q3QA 3GTGA 4LOWA 4A3KK 3V4GA 4GTAA 2CW0A 4A3DK 3PO2K 4Q4ZA 2R7ZA 2O5JA 2NVXC 4A3IK 3TFIA 5C4JC 4YG2A 3N0BA 1EFWA 2E2HA 2PA8L 3S1MC 4LK0A 1F9NA 2A69A 4LJZA 3CAGA 4C3IK 3M3YC 2YU9C 5M5WK 1O29A 3JSTA 1AB4A 5IYBK 1HI9A 1K83C 3GTGK 3S16K 4ZH4A 3G4AA 2NVTK 4A3KC 1J6VA 3AH5A 2R7ZK 2NVYC 1IS1A 2JA5K 3PO2C 2P8TA 1HQMA 3I4NK 5M5YK 1JQWA 2E2HK 4FM9A 4A3BK 4A3IC 4Y7NK 5IOQA 4ILDA 3K7AK 3S1QC 4PAAA 4LR2A 1ZYRA 5CHPA 3FOFA 1TWFC 1SFOC 2A68A 5IYBC 3EQLA 4Y52K 3GTGC 2GAGC 3AQPA 3GTJA 2R7ZC 3S1RK 5IP7K 4A3FK 4WJ4A 5C3EK 2E2HC 5TMFA 1I50K 4C2MK 4LQYA 3RZDK 5IP9K 1GE9A 4M1XA 1I6HC 4OIPA 4Y52C 4Q5SA 1L0WA 4J3NA 4KB4A 2GSOA 3GEHA 4KB2A 1WQHA 1O2BA 3S1RC 3GTPK 1TWAA 1IBAA 3S2DC 5C3EC 2GSUA 3M4OK 4P5AA 1XZQA 3RZDC 4QJVB 1ZVUA 3GTLC 4G0VA 5IP9C 5EGHA 1EQRA 1XPPA 4A3GK 1BS2A 1J6WA 1I6VA 1YNJA 1Y1VA 5L46A 3GTJC 5C4JK 4BXXC 2JA6A 3SZYA 4YFXA 3S1MK 2JH3A 3HKZL 3HOWK 1IE0A 1RU0A
chains in the Genus database with same CATH topology
2V6UA 1USOA 1USMA 1F93A 2V6TA 1DCPA 3HXAA 2V6SA 4LOWA 4WILA 1DCOA 1DCHA 1RU0A 2EBBA 3JSTA 4C45A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2V6U A;  1USO A;  1USM A;  1F93 A;  2V6T A;  1DCP A;  3HXA A;  2V6S A;  4LOW A;  4WIL A;  1DCO A;  1DCH A;  1RU0 A;  2EBB A;  3JST A;  4C45 A; 
#chains in the Genus database with same CATH topology
 2A6H A;  2V6U A;  2BE5 A;  3HKZ D;  3FKI A;  3HOV C;  4A3C K;  1WOS A;  4A3M C;  4BBS K;  3AD8 C;  1B4B A;  1DCO A;  5FLM C;  1IW7 A;  2ZUF A;  3I4M K;  2NVY K;  2R92 A;  5IYD C;  4A3G C;  3T02 A;  2RH6 A;  2RGR A;  2JA6 K;  3CQZ A;  3ORE A;  2B63 A;  3G4C A;  1F93 A;  4KM8 A;  3HOX K;  3GIR A;  3GTK A;  4BY1 K;  2GSN A;  3S1Q K;  3H3V L;  2Y3P A;  1TWA C;  3HOW C;  3HXA A;  3N3Y A;  3GTO C;  1TWF K;  1SFO K;  3PO3 K;  4BLB A;  3H3V D;  1TWH A;  4LK1 A;  1JVI A;  4A3C C;  4BBS C;  3BP3 A;  4XSX A;  4GTB A;  1YNN A;  4C3J C;  3S17 C;  4YFN A;  3I4M C;  3HOZ C;  1WSR A;  1Y1V C;  1O25 A;  2B63 K;  1B4A A;  5IOS A;  2JA6 C;  3GTK K;  2CFA B;  5M5X K;  3HOX C;  4BY1 C;  4BBR C;  4C3H C;  1WCM A;  2PPB A;  3H0G A;  3DXJ A;  3AQO A;  3FKI C;  3TTG A;  3GTL A;  1UV7 A;  1I3Q A;  3PO3 C;  1ZXO A;  2JA7 A;  1I6H K;  2PHC B;  4WIL A;  2P5M A;  5JVO A;  1TWG A;  2NVQ C;  4KAW X;  4P9S A;  2R92 C;  3S2H C;  2WAQ L;  1R9T A;  3FOE A;  2ZFZ A;  3NUH A;  5M3M K;  5IOR A;  1USO A;  2KWA A;  3CQZ C;  2WAQ D;  3SZZ A;  4G7Z A;  2B63 C;  3S2D K;  3BUE A;  3GTK C;  2VUM A;  3GDZ A;  2V6S A;  4BLA A;  3H0G K;  3S15 K;  4O2D A;  5TMC A;  1WOR A;  3GTL K;  1I3Q K;  1BDF A;  4JK1 A;  3RZO K;  4A93 C;  1TWH C;  4KAS A;  3A8K A;  4DDQ A;  1TWC A;  1TWG K;  3OPF A;  4KMH A;  3GTJ K;  4BXX K;  2R93 A;  1R9T K;  1J98 A;  2D6F C;  1BJT A;  3ERE D;  4GT9 A;  1WIH A;  3HOU K;  1WQG A;  4AH6 A;  3GTO A;  4BY7 C;  3HOV K;  2Y0S L;  1DCH A;  4A3M K;  4GFQ A;  1WCM C;  1YX2 A;  5IYC C;  5CJ9 A;  3H0G C;  3GEI A;  3S15 C;  5FLM K;  2CFA A;  1I3Q C;  1TWC K;  2Y0S D;  4MEY A;  3HOY C;  2JA7 C;  3RZO C;  3GTQ A;  3GSI A;  5IYD K;  2R93 K;  1TWG C;  2W7V A;  2XCQ A;  4A3L C;  4XLN A;  3VA7 A;  5C44 C;  1R9T C;  3A8J A;  3GTM A;  3L4J A;  1TWA K;  2ZUE A;  3GTO K;  2VUM C;  3HOU C;  3A8I A;  3L4K A;  1O2F B;  4KMA A;  1WOP A;  1EI6 A;  5IOT A;  1VJE A;  3T00 A;  4C3J K;  4X6A K;  2FQO A;  3S17 K;  1WOO A;  1TWC C;  1PJ6 A;  3HOZ K;  1Y1V K;  3AD7 C;  1J6X A;  2R93 C;  1XXB A;  3LAP A;  4XSZ A;  4AYB D;  1ZBS A;  4BBR K;  4KAT A;  1IQ0 A;  2XCO A;  4C3H K;  1O2A A;  1F7V A;  1PJ7 A;  3FKI K;  4P5B A;  3IPJ A;  1USM A;  4GZY A;  2E2J C;  1O27 A;  2NVQ K;  1Y1W A;  1KQ4 A;  4C45 A;  4FZB A;  5FJ8 K;  2E2I A;  2R92 K;  3GTQ C;  3S2H K;  3T01 A;  2WB1 L;  4X6A C;  1VLO A;  2JA5 A;  3LAJ A;  2PMZ L;  4KN4 A;  3MML B;  3FHZ A;  3CQZ K;  2GAH C;  3GTM C;  2WB1 D;  3GEE A;  4QJV A;  2O5I A;  1WQF A;  1VH2 A;  4MQ9 A;  2PMZ D;  3BP8 C;  2PA8 D;  1INN A;  4A3J C;  5JFE A;  4A93 K;  1TWH K;  4PAB A;  1SMY A;  1XXC A;  1Y1W K;  2E2I K;  4G7H A;  3WOD A;  4A3D C;  4KMU A;  1G51 A;  4NOI A;  1EK8 A;  1XZQ B;  5HL8 A;  1O28 A;  1BGW A;  3OEP A;  4QIW L;  4RMF A;  1I50 A;  4BY7 K;  1WCM K;  4QIW D;  4C3I C;  5IYC K;  1VGX A;  4KN7 A;  4XLP A;  1F7U A;  5EGE A;  1ZQ1 C;  3HOY K;  2JA7 K;  3S16 C;  1VRQ C;  3QX3 A;  4OIN A;  3S14 K;  1DD5 A;  3S1N K;  1XZP B;  2V6T A;  3ADA C;  3N0C A;  1Y1W C;  2NVT C;  4A3L K;  2JA8 K;  2E2I C;  3AD9 C;  3LPX A;  5C44 K;  3TFH A;  2A6E A;  1O24 A;  2JA5 C;  1WSV A;  5C4X K;  1V5V A;  3I4N C;  3GTP A;  1X31 C;  4A3B C;  4Y7N C;  4GTE A;  4A3E K;  4G7O A;  4G0U A;  1YCL A;  3K7A C;  2VUM K;  4YFK A;  2XCR B;  4KC6 A;  4OIO A;  4BKW A;  4G0W A;  4GTC A;  4WJ3 M;  5TJ3 A;  5E68 A;  3S14 C;  2NVX A;  3S1N C;  5M3F K;  2JA8 C;  5D4D A;  4KM9 A;  1EH1 A;  5IP7 C;  4A3F C;  5C4X C;  3S0X A;  4KMD A;  1IL2 A;  2YU9 A;  4A3E C;  4OIR A;  1I50 C;  4MEX A;  4LLG A;  4C2M C;  1XXA A;  3TFJ A;  1K83 A;  4OIQ A;  2E2J K;  1JOE A;  2FQT A;  2NVY A;  3GTQ K;  4KAR A;  1DCP A;  2NVX K;  4XCH A;  4AYB L;  1ISE A;  2EBB A;  4GTD A;  3GTM K;  1PJ5 A;  1O26 A;  4GTL A;  3GTP C;  3M3Y K;  1XZP A;  2YU9 K;  4KDD A;  4A3J K;  4GTF A;  1C0A A;  1TWF A;  1SFO A;  3M4O C;  1K83 K;  3Q3Q A;  3GTG A;  4LOW A;  4A3K K;  3V4G A;  4GTA A;  2CW0 A;  4A3D K;  3PO2 K;  4Q4Z A;  2R7Z A;  2O5J A;  2NVX C;  4A3I K;  3TFI A;  5C4J C;  4YG2 A;  3N0B A;  1EFW A;  2E2H A;  2PA8 L;  3S1M C;  4LK0 A;  1F9N A;  2A69 A;  4LJZ A;  3CAG A;  4C3I K;  3M3Y C;  2YU9 C;  5M5W K;  1O29 A;  3JST A;  1AB4 A;  5IYB K;  1HI9 A;  1K83 C;  3GTG K;  3S16 K;  4ZH4 A;  3G4A A;  2NVT K;  4A3K C;  1J6V A;  3AH5 A;  2R7Z K;  2NVY C;  1IS1 A;  2JA5 K;  3PO2 C;  2P8T A;  1HQM A;  3I4N K;  5M5Y K;  1JQW A;  2E2H K;  4FM9 A;  4A3B K;  4A3I C;  4Y7N K;  5IOQ A;  4ILD A;  3K7A K;  3S1Q C;  4PAA A;  4LR2 A;  1ZYR A;  5CHP A;  3FOF A;  1TWF C;  1SFO C;  2A68 A;  5IYB C;  3EQL A;  4Y52 K;  3GTG C;  2GAG C;  3AQP A;  3GTJ A;  2R7Z C;  3S1R K;  5IP7 K;  4A3F K;  4WJ4 A;  5C3E K;  2E2H C;  5TMF A;  1I50 K;  4C2M K;  4LQY A;  3RZD K;  5IP9 K;  1GE9 A;  4M1X A;  1I6H C;  4OIP A;  4Y52 C;  4Q5S A;  1L0W A;  4J3N A;  4KB4 A;  2GSO A;  3GEH A;  4KB2 A;  1WQH A;  1O2B A;  3S1R C;  3GTP K;  1TWA A;  1IBA A;  3S2D C;  5C3E C;  2GSU A;  3M4O K;  4P5A A;  1XZQ A;  3RZD C;  4QJV B;  1ZVU A;  3GTL C;  4G0V A;  5IP9 C;  5EGH A;  1EQR A;  1XPP A;  4A3G K;  1BS2 A;  1J6W A;  1I6V A;  1YNJ A;  1Y1V A;  5L46 A;  3GTJ C;  5C4J K;  4BXX C;  2JA6 A;  3SZY A;  4YFX A;  3S1M K;  2JH3 A;  3HKZ L;  3HOW K;  1IE0 A;  1RU0 A; 
#chains in the Genus database with same CATH homology
 2V6U A;  1USO A;  1USM A;  1F93 A;  2V6T A;  1DCP A;  3HXA A;  2V6S A;  4LOW A;  4WIL A;  1DCO A;  1DCH A;  1RU0 A;  2EBB A;  3JST A;  4C45 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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