1USMA

Dcoh, a bifunctional protein-binding transcriptional coactivator, pro9leu mutant
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
80
structure length
77
Chain Sequence
MDWEERKRLVKTFAFPNFREALDFANRVGALAERENHHPRLTVEWGRVTVEWWTHSAGGVTEKDREMARLTDALLQR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transcriptional stimulator
molecule keywords HEPATOCYTE NUCLEAR FACTOR 1-ALPHA
publication title Crystal Structure of Transcriptional Coactivator DCoH from Thermus Thermophilus
rcsb
source organism Thermus thermophilus
total genus 23
structure length 77
sequence length 80
ec nomenclature
pdb deposition date 2003-11-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01329 Pterin_4a Pterin 4 alpha carbinolamine dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1360.20 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 Transcriptional coactivator/pterin dehydratase 1usmA00
1USOA 4C45A 3HXAA 2V6UA 4WILA 1DCOA 2EBBA 2V6SA 1F93A 1RU0A 1DCPA 2V6TA 1DCHA 3JSTA 4LOWA 1USMA
chains in the Genus database with same CATH superfamily
3M3YK 3T00A 1B4BA 1SFOC 1J98A 3HOZC 5C3EC 2B63K 2E2IK 1WOPA 1ZQ1C 2FQTA 2PPBA 1EI6A 3N0BA 4AH6A 3JSTA 1V5VA 4A3CC 3H0GC 4P5AA 3ADAC 5IP9C 4OIPA 4A3KC 4Q5SA 4C3HK 4G7ZA 2WAQD 4A3DC 1O27A 4KMHA 5M5XK 2B63A 1I3QK 3S2DK 3CQZK 3HXAA 4A3JC 4A3MC 1TWFC 3N0CA 1K83C 2R92K 4O2DA 1ISEA 5IYBC 1O2BA 2RGRA 3GTOK 1WCMA 4GTCA 3CAGA 1EH1A 1TWHC 4GTEA 1USMA 1YNNA 3AH5A 1I50K 2NVTK 3HOVK 1F9NA 4KN7A 3PO2C 3RZOK 4XSXA 1TWGA 4KASA 4A3EK 1WQFA 3EQLA 4Y7NC 3OPFA 1R9TA 4YFXA 1PJ5A 5M5YK 2XCRB 2R7ZA 4XSZA 2GAGC 1TWAA 3SZZA 3GTLC 3S1QC 1I50A 3S1MK 4OIOA 4BBRK 4BLBA 4RMFA 2GSUA 5FLMC 1GE9A 3M4OC 1O2FB 3QX3A 4KM8A 4BXXK 3HOYC 1TWCK 1EFWA 5TMFA 4AYBL 3GTQK 5IOSA 1Y1VK 1IQ0A 1F93A 2V6TA 2ZFZA 1XPPA 4LR2A 5C4JK 4DDQA 2JA6C 1XXAA 3PO3K 4KC6A 4C2MC 2E2JC 3SZYA 5CJ9A 2YU9A 3I4MK 2NVQK 2E2HC 4G0VA 1WQHA 3S0XA 3GTKK 1BS2A 2JA5A 1WOSA 3V4GA 1Y1WK 1WOOA 5M5WK 1O28A 4GTFA 2VUMA 1DCPA 4C3JK 5IYCC 1XZPA 3IPJA 5TMCA 3S16C 1XZPB 3GTGK 3DXJA 5IYDC 1IW7A 4BY7K 2PA8D 2JA7A 1KQ4A 2R93K 3GTPA 1WIHA 5CHPA 1UV7A 3GTJA 2GSOA 4Y52C 4A3LK 5M3MK 2Y0SL 4MEXA 3NUHA 3GSIA 4Q4ZA 3FOEA 3LAJA 2RH6A 4A3IC 3GEHA 4P9SA 4XLPA 1I6HK 1VJEA 4X6AC 1IBAA 3S14C 1WCMC 1YCLA 3FKIA 2JA8C 3S15K 2NVYK 5IP7C 4A3BK 5JFEA 1TWGC 3G4AA 3ERED 3RZDK 4A93C 1R9TC 1SMYA 3OEPA 2D6FC 4BBSC 1ZBSA 1VGXA 5C4XK 4C3IC 2R7ZC 2E2IA 5FJ8K 4QJVA 1TWAC 2V6SA 4KAWX 4WJ4A 3S1RC 1I50C 4QJVB 2NVTC 1SFOK 3HOZK 5C3EK 3H3VD 1L0WA 1DCHA 3AD9C 1I3QA 4A3CK 5JVOA 3LAPA 1J6WA 3CQZA 5IP9K 4A3KK 4BY1C 2PMZD 3S1MC 3GTMC 2V6UA 4YFNA 4A3DK 2R92A 5HL8A 4ZH4A 4FZBA 3GTOA 4G0UA 4A3JK 4A3MK 1TWFK 3MMLB 1O26A 1PJ7A 1K83K 2YU9C 3AD8C 3S1NC 1INNA 5IYBK 3T01A 1F7VA 1TWHK 1BDFA 3GEIA 3LPXA 3PO2K 2WB1D 5IOTA 2JA5C 5IOQA 2XCQA 3HOWK 4KMUA 5L46A 1USOA 3HOXC 3GDZA 4WILA 4Y7NK 3TFIA 2VUMC 3L4KA 4QIWD 2GSNA 2GAHC 3AD7C 4JK1A 3S17C 4A3GC 1TWHA 1WQGA 3GTLK 5TJ3A 2JA7C 3S1QK 4FM9A 1BGWA 3GTPC 3T02A 3GTJC 1IL2A 4YG2A 3A8KA 1TWCA 2O5JA 3GTQA 3WODA 1Y1VA 5FLMK 2A69A 1IS1A 3L4JA 4A3FC 1J6VA 3HOUC 3TTGA 3HOYK 1HI9A 4MQ9A 2WAQL 4PABA 5EGEA 1YNJA 1DD5A 3FKIC 3I4NC 4P5BA 4M1XA 1EQRA 4LOWA 1PJ6A 4LK1A 4A3LC 2JH3A 3TFHA 4KMAA 2JA6K 3K7AC 4GFQA 3GTKA 4C2MK 2E2JK 3M3YC 5M3FK 1JVIA 1Y1WA 1WSRA 1X31C 2BE5A 2E2HK 2B63C 2E2IC 3TFJA 4WJ3M 4BLAA 3H3VL 3S15C 1XZQA 3AQPA 5C44K 3GTGA 2ZUFA 1XZQB 4J3NA 3S2HK 1YX2A 4LQYA 2R93A 2JA6A 3GIRA 2NVXK 5IYCK 2PMZL 4GTBA 4C3HC 2ZUEA 3S16K 1I3QC 5IYDK 3S2DC 3CQZC 4C45A 4KATA 1O25A 2A6HA 3A8IA 4G0WA 1F7UA 2R92C 1JOEA 2CFAA 4Y52K 4KMDA 3GTOC 2NVXA 2CFAB 4NOIA 2NVYA 3HOVC 2WB1L 3RZOC 2KWAA 4A3IK 2CW0A 3GEEA 4A3EC 4X6AK 3BP3A 3S14K 4KB4A 1J6XA 1WCMK 4GZYA 4PAAA 2JA8K 4QIWL 2P8TA 5IP7K 2A68A 3H0GK 1AB4A 1TWGK 3FOFA 1EK8A 2FQOA 4A93K 1R9TK 2O5IA 1HQMA 2W7VA 4GT9A 3HKZD 4YFKA 1SFOA 1RU0A 4BBRC 4BBSK 4C3IK 2R7ZK 1VRQC 5IORA 1TWAK 2Y0SD 4MEYA 1XXBA 3S1RK 1O29A 4OINA 3H0GA 4BXXC 3HOWC 1TWCC 3GTQC 1Y1VC 4GTAA 4KM9A 2P5MA 4KDDA 2Y3PA 4G7HA 3OREA 5C4JC 2PA8L 1XXCA 4OIRA 1TWFA 3PO3C 4BY1K 4BKWA 1K83A 1B4AA 3GTMK 4XLNA 3I4MC 2NVQC 3AQOA 3FHZA 3G4CA 1IE0A 1BJTA 3GTKC 1ZXOA 2YU9K 1Y1WC 1WORA 4KB2A 5EGHA 3S1NK 3VA7A 4C3JC 4G7OA 4OIQA 5E68A 3M4OK 3GTMA 3N3YA 2JA5K 3GTGC 4KN4A 4GTLA 1I6VA 4LK0A 3HOXK 3GTLA 4BY7C 2R93C 2VUMK 1VLOA 4GTDA 1C0AA 1WSVA 3BUEA 5D4DA 3A8JA 3S17K 4A3GK 2XCOA 1O24A 2JA7K 1ZYRA 4LLGA 5C44C 3GTPK 3GTJK 3Q3QA 1I6HC 3S2HC 2A6EA 2NVXC 1VH2A 2NVYC 4LJZA 4A3BC 4A3FK 1JQWA 1DCOA 2EBBA 3HOUK 3RZDC 2PHCB 1O2AA 4AYBD 3HKZL 1ZVUA 4XCHA 3FKIK 3I4NK 3BP8C 4KARA 5C4XC 2E2HA 4ILDA 1G51A 3K7AK
chains in the Genus database with same CATH topology
1USOA 4C45A 3HXAA 2V6UA 4WILA 1DCOA 2EBBA 2V6SA 1F93A 1RU0A 1DCPA 2V6TA 1DCHA 3JSTA 4LOWA 1USMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1USO A;  4C45 A;  3HXA A;  2V6U A;  4WIL A;  1DCO A;  2EBB A;  2V6S A;  1F93 A;  1RU0 A;  1DCP A;  2V6T A;  1DCH A;  3JST A;  4LOW A;  1USM A; 
#chains in the Genus database with same CATH topology
 3M3Y K;  3T00 A;  1B4B A;  1SFO C;  1J98 A;  3HOZ C;  5C3E C;  2B63 K;  2E2I K;  1WOP A;  1ZQ1 C;  2FQT A;  2PPB A;  1EI6 A;  3N0B A;  4AH6 A;  3JST A;  1V5V A;  4A3C C;  3H0G C;  4P5A A;  3ADA C;  5IP9 C;  4OIP A;  4A3K C;  4Q5S A;  4C3H K;  4G7Z A;  2WAQ D;  4A3D C;  1O27 A;  4KMH A;  5M5X K;  2B63 A;  1I3Q K;  3S2D K;  3CQZ K;  3HXA A;  4A3J C;  4A3M C;  1TWF C;  3N0C A;  1K83 C;  2R92 K;  4O2D A;  1ISE A;  5IYB C;  1O2B A;  2RGR A;  3GTO K;  1WCM A;  4GTC A;  3CAG A;  1EH1 A;  1TWH C;  4GTE A;  1USM A;  1YNN A;  3AH5 A;  1I50 K;  2NVT K;  3HOV K;  1F9N A;  4KN7 A;  3PO2 C;  3RZO K;  4XSX A;  1TWG A;  4KAS A;  4A3E K;  1WQF A;  3EQL A;  4Y7N C;  3OPF A;  1R9T A;  4YFX A;  1PJ5 A;  5M5Y K;  2XCR B;  2R7Z A;  4XSZ A;  2GAG C;  1TWA A;  3SZZ A;  3GTL C;  3S1Q C;  1I50 A;  3S1M K;  4OIO A;  4BBR K;  4BLB A;  4RMF A;  2GSU A;  5FLM C;  1GE9 A;  3M4O C;  1O2F B;  3QX3 A;  4KM8 A;  4BXX K;  3HOY C;  1TWC K;  1EFW A;  5TMF A;  4AYB L;  3GTQ K;  5IOS A;  1Y1V K;  1IQ0 A;  1F93 A;  2V6T A;  2ZFZ A;  1XPP A;  4LR2 A;  5C4J K;  4DDQ A;  2JA6 C;  1XXA A;  3PO3 K;  4KC6 A;  4C2M C;  2E2J C;  3SZY A;  5CJ9 A;  2YU9 A;  3I4M K;  2NVQ K;  2E2H C;  4G0V A;  1WQH A;  3S0X A;  3GTK K;  1BS2 A;  2JA5 A;  1WOS A;  3V4G A;  1Y1W K;  1WOO A;  5M5W K;  1O28 A;  4GTF A;  2VUM A;  1DCP A;  4C3J K;  5IYC C;  1XZP A;  3IPJ A;  5TMC A;  3S16 C;  1XZP B;  3GTG K;  3DXJ A;  5IYD C;  1IW7 A;  4BY7 K;  2PA8 D;  2JA7 A;  1KQ4 A;  2R93 K;  3GTP A;  1WIH A;  5CHP A;  1UV7 A;  3GTJ A;  2GSO A;  4Y52 C;  4A3L K;  5M3M K;  2Y0S L;  4MEX A;  3NUH A;  3GSI A;  4Q4Z A;  3FOE A;  3LAJ A;  2RH6 A;  4A3I C;  3GEH A;  4P9S A;  4XLP A;  1I6H K;  1VJE A;  4X6A C;  1IBA A;  3S14 C;  1WCM C;  1YCL A;  3FKI A;  2JA8 C;  3S15 K;  2NVY K;  5IP7 C;  4A3B K;  5JFE A;  1TWG C;  3G4A A;  3ERE D;  3RZD K;  4A93 C;  1R9T C;  1SMY A;  3OEP A;  2D6F C;  4BBS C;  1ZBS A;  1VGX A;  5C4X K;  4C3I C;  2R7Z C;  2E2I A;  5FJ8 K;  4QJV A;  1TWA C;  2V6S A;  4KAW X;  4WJ4 A;  3S1R C;  1I50 C;  4QJV B;  2NVT C;  1SFO K;  3HOZ K;  5C3E K;  3H3V D;  1L0W A;  1DCH A;  3AD9 C;  1I3Q A;  4A3C K;  5JVO A;  3LAP A;  1J6W A;  3CQZ A;  5IP9 K;  4A3K K;  4BY1 C;  2PMZ D;  3S1M C;  3GTM C;  2V6U A;  4YFN A;  4A3D K;  2R92 A;  5HL8 A;  4ZH4 A;  4FZB A;  3GTO A;  4G0U A;  4A3J K;  4A3M K;  1TWF K;  3MML B;  1O26 A;  1PJ7 A;  1K83 K;  2YU9 C;  3AD8 C;  3S1N C;  1INN A;  5IYB K;  3T01 A;  1F7V A;  1TWH K;  1BDF A;  3GEI A;  3LPX A;  3PO2 K;  2WB1 D;  5IOT A;  2JA5 C;  5IOQ A;  2XCQ A;  3HOW K;  4KMU A;  5L46 A;  1USO A;  3HOX C;  3GDZ A;  4WIL A;  4Y7N K;  3TFI A;  2VUM C;  3L4K A;  4QIW D;  2GSN A;  2GAH C;  3AD7 C;  4JK1 A;  3S17 C;  4A3G C;  1TWH A;  1WQG A;  3GTL K;  5TJ3 A;  2JA7 C;  3S1Q K;  4FM9 A;  1BGW A;  3GTP C;  3T02 A;  3GTJ C;  1IL2 A;  4YG2 A;  3A8K A;  1TWC A;  2O5J A;  3GTQ A;  3WOD A;  1Y1V A;  5FLM K;  2A69 A;  1IS1 A;  3L4J A;  4A3F C;  1J6V A;  3HOU C;  3TTG A;  3HOY K;  1HI9 A;  4MQ9 A;  2WAQ L;  4PAB A;  5EGE A;  1YNJ A;  1DD5 A;  3FKI C;  3I4N C;  4P5B A;  4M1X A;  1EQR A;  4LOW A;  1PJ6 A;  4LK1 A;  4A3L C;  2JH3 A;  3TFH A;  4KMA A;  2JA6 K;  3K7A C;  4GFQ A;  3GTK A;  4C2M K;  2E2J K;  3M3Y C;  5M3F K;  1JVI A;  1Y1W A;  1WSR A;  1X31 C;  2BE5 A;  2E2H K;  2B63 C;  2E2I C;  3TFJ A;  4WJ3 M;  4BLA A;  3H3V L;  3S15 C;  1XZQ A;  3AQP A;  5C44 K;  3GTG A;  2ZUF A;  1XZQ B;  4J3N A;  3S2H K;  1YX2 A;  4LQY A;  2R93 A;  2JA6 A;  3GIR A;  2NVX K;  5IYC K;  2PMZ L;  4GTB A;  4C3H C;  2ZUE A;  3S16 K;  1I3Q C;  5IYD K;  3S2D C;  3CQZ C;  4C45 A;  4KAT A;  1O25 A;  2A6H A;  3A8I A;  4G0W A;  1F7U A;  2R92 C;  1JOE A;  2CFA A;  4Y52 K;  4KMD A;  3GTO C;  2NVX A;  2CFA B;  4NOI A;  2NVY A;  3HOV C;  2WB1 L;  3RZO C;  2KWA A;  4A3I K;  2CW0 A;  3GEE A;  4A3E C;  4X6A K;  3BP3 A;  3S14 K;  4KB4 A;  1J6X A;  1WCM K;  4GZY A;  4PAA A;  2JA8 K;  4QIW L;  2P8T A;  5IP7 K;  2A68 A;  3H0G K;  1AB4 A;  1TWG K;  3FOF A;  1EK8 A;  2FQO A;  4A93 K;  1R9T K;  2O5I A;  1HQM A;  2W7V A;  4GT9 A;  3HKZ D;  4YFK A;  1SFO A;  1RU0 A;  4BBR C;  4BBS K;  4C3I K;  2R7Z K;  1VRQ C;  5IOR A;  1TWA K;  2Y0S D;  4MEY A;  1XXB A;  3S1R K;  1O29 A;  4OIN A;  3H0G A;  4BXX C;  3HOW C;  1TWC C;  3GTQ C;  1Y1V C;  4GTA A;  4KM9 A;  2P5M A;  4KDD A;  2Y3P A;  4G7H A;  3ORE A;  5C4J C;  2PA8 L;  1XXC A;  4OIR A;  1TWF A;  3PO3 C;  4BY1 K;  4BKW A;  1K83 A;  1B4A A;  3GTM K;  4XLN A;  3I4M C;  2NVQ C;  3AQO A;  3FHZ A;  3G4C A;  1IE0 A;  1BJT A;  3GTK C;  1ZXO A;  2YU9 K;  1Y1W C;  1WOR A;  4KB2 A;  5EGH A;  3S1N K;  3VA7 A;  4C3J C;  4G7O A;  4OIQ A;  5E68 A;  3M4O K;  3GTM A;  3N3Y A;  2JA5 K;  3GTG C;  4KN4 A;  4GTL A;  1I6V A;  4LK0 A;  3HOX K;  3GTL A;  4BY7 C;  2R93 C;  2VUM K;  1VLO A;  4GTD A;  1C0A A;  1WSV A;  3BUE A;  5D4D A;  3A8J A;  3S17 K;  4A3G K;  2XCO A;  1O24 A;  2JA7 K;  1ZYR A;  4LLG A;  5C44 C;  3GTP K;  3GTJ K;  3Q3Q A;  1I6H C;  3S2H C;  2A6E A;  2NVX C;  1VH2 A;  2NVY C;  4LJZ A;  4A3B C;  4A3F K;  1JQW A;  1DCO A;  2EBB A;  3HOU K;  3RZD C;  2PHC B;  1O2A A;  4AYB D;  3HKZ L;  1ZVU A;  4XCH A;  3FKI K;  3I4N K;  3BP8 C;  4KAR A;  5C4X C;  2E2H A;  4ILD A;  1G51 A;  3K7A K; 
#chains in the Genus database with same CATH homology
 1USO A;  4C45 A;  3HXA A;  2V6U A;  4WIL A;  1DCO A;  2EBB A;  2V6S A;  1F93 A;  1RU0 A;  1DCP A;  2V6T A;  1DCH A;  3JST A;  4LOW A;  1USM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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