3NUHA

A domain insertion in e. coli gyrb adopts a novel fold that plays a critical role in gyrase function
Total Genus 138
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
138
sequence length
506
structure length
485
Chain Sequence
SSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANPWVAAMLEDAARPEWLEPEFLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITAN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Isomerase
molecule keywords DNA gyrase subunit A
publication title A domain insertion in Escherichia coli GyrB adopts a novel fold that plays a critical role in gyrase function.
pubmed doi rcsb
source organism Escherichia coli
total genus 138
structure length 485
sequence length 506
ec nomenclature ec 5.99.1.3: Transferred entry: 5.6.2.3.
pdb deposition date 2010-07-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00521 DNA_topoisoIV DNA gyrase/topoisomerase IV, subunit A
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.268.10 Mainly Alpha Orthogonal Bundle Topoisomerase; domain 3 Topoisomerase, domain 3 3nuhA03
3.30.1360.40 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 Gyrase A; domain 2 3nuhA02
3.90.199.10 Alpha Beta Alpha-Beta Complex Topoisomerase II; domain 5 Topoisomerase II, domain 5 3nuhA01
1DD5A 2Y3PA 4GFQA 4CKLA 1B4AA 1WIHA 3FHZA 3BUEA 3OEPA 1XXAA 4ELZA 1XXBA 1B4BA 3ERED 4ELYA 3FOFA 2P5MA 3MMLB 4G0WA 1WQGA 1X75A 4KC6A 1WQFA 3V4GA 1ZVUA 1BGWA 4J3NA 1EK8A 5CJ9A 1IS1A 4DDQA 1BJTA 4Z3OA 1WQHA 1EH1A 5JVOA 1GE9A 4Z4QA 3L4JA 4Z53A 1XXCA 2KWAA 4CKKA 3OREA 2RGRA 1ISEA 4KB2A 3CAGA 4KDDA 4G0VA 3LAPA 4FM9A 2ZFZA 4KB4A 1AB4A 3NUHA 4TMAA 2XCOA 2XCRB 3L4KA 2XCQA 3QX3A 4G0UA 1F9NA 3OPFA 4KAWX 3LAJA 3FOEA 3LPXA 3VA7A 2PHCB
chains in the Genus database with same CATH superfamily
2VUMC 2NVTK 4PAAA 1YCLA 4KM9A 4C3JC 5M3MK 1TWFK 2D6FC 2JA7C 1O24A 3I4MC 4G0WA 1TWHA 1IQ0A 3HOWC 1WQFA 2R7ZC 3HOZC 4Z4QA 1VJEA 2V6TA 4OIOA 3PO2C 3T01A 5C4JK 1SFOK 1TWFA 2GSOA 3S14K 5M5YK 4GTAA 4CIDA 5TMFA 4AYBL 5C44K 3SZYA 3ERED 4BBRC 2GSUA 2PMZL 1WSRA 1RU0A 4GTEA 4A3KK 3M3YC 1BGWA 4O2DA 5IOQA 5IP9K 4DDQA 4Z3OA 4Y52C 3S2DK 2E2IC 2O5JA 2NVYC 4FM9A 5IP7K 4G0UA 3QX3A 2XCQA 1Y1VC 4WILA 4OIRA 3S1NK 1F93A 2PHCB 3VA7A 4A3BC 3I4NC 1L0WA 3AD8C 4A3DC 3A8KA 3GTOC 1XZQA 1PJ5A 3HKZL 1TWCK 5C3EK 4C3HK 1EI6A 4G7OA 1O29A 4KASA 2A69A 3N0BA 4Z53A 2A6EA 3GEIA 2YU9C 2B63K 4A3CK 1K83C 4KN4A 1TWCA 3HOVC 1TWGC 3H0GK 5IYBC 3GTLC 3GTQC 2Y3PA 3Q3QA 3FHZA 1O2FB 3OEPA 3TTGA 2Y0SD 4BY7C 3ADAC 2VUMK 4Y7NK 1VGXA 3TFHA 4ELYA 4A3EC 3RZOC 4A93C 4KC6A 4C3JK 2NVXA 4BLAA 2JH3A 1EK8A 4A3JC 2B63A 4OIQA 4LK1A 3PO3K 1VH2A 3H0GA 4WJ4A 3CAGA 3RZDK 1I6HC 4BXXC 4KB4A 3S1QC 3NUHA 1VRQC 4BLBA 2VUMA 1WSVA 2E2JK 4GTCA 1JQWA 1V5VA 3GTGC 4BBSC 5M5WK 4GTLA 1BDFA 3HOYC 1O26A 3A8IA 4QIWD 4BBRK 5CJ9A 4YFKA 1R9TC 3S16K 4A3LK 4BY1K 3FKIK 5HL8A 4C45A 4KAWX 4PABA 1J98A 4LJZA 2JA8C 5FLMC 1Y1VK 1EFWA 1WOSA 2R93C 2JA6K 3I4NK 4RMFA 1WQGA 2E2HK 4M1XA 4A3GK 3FKIA 2NVQC 3A8JA 2E2IA 5JVOA 3EQLA 2WB1D 1Y1VA 2FQTA 3CQZC 1AB4A 3L4KA 1BS2A 3S15K 3HOUK 3HOXK 4JK1A 2JA6A 4AH6A 2E2HA 4QJVB 3S17K 3S1RK 5EGEA 5IYBK 5M5XK 1JVIA 3GEEA 2W7VA 4KMUA 4QJVA 4X6AC 2RH6A 4G7HA 4P9SA 2YU9A 4A3JK 4FZBA 1J6VA 4KATA 4P5BA 5IYDK 1YNJA 2JA5C 1X31C 4GT9A 4BKWA 2WAQD 1F9NA 2R92C 4BXXK 5IYCK 3S1MC 3S2HK 3M4OC 5TJ3A 2BE5A 4A3MC 5L46A 4C2MC 2GAHC 1ZQ1C 1B4BA 1WCMC 4BBSK 4J3NA 1TWHC 1PJ7A 1O25A 3L4JA 4XCHA 3SZZA 5C4XK 2EBBA 4GTFA 1G51A 4A3IK 3H3VD 2ZFZA 3GTKC 2NVXK 3N0CA 4TMAA 2NVTC 2XCOA 1HI9A 4GTBA 1TWFC 2O5IA 5E68A 4GFQA 4LK0A 4C3IK 1ZYRA 4ELZA 3GSIA 4XLPA 5JFEA 3GTPC 4NOIA 4GZYA 2JA7K 1I3QC 1WQHA 1EH1A 3I4MK 5C4JC 3HOWK 3GTMC 1SFOC 3S14C 2A6HA 1I6VA 2R7ZK 3HOZK 1O2BA 5IORA 2XCRB 5C44C 3GTJC 3GDZA 3FOEA 5FJ8K 2V6UA 3PO2K 4P5AA 1YNNA 1DCOA 2JA7A 5IP9C 1VLOA 1IE0A 3S2DC 3AD9C 2R7ZA 4KMAA 1XZPB 4XSXA 5IP7C 2GSNA 3M3YK 2KWAA 3S1NC 4LR2A 3T02A 1Y1WC 3AH5A 3DXJA 2PMZD 4Y52K 2E2IK 2QPTA 2JA5K 2CFAB 2NVYK 1TWCC 1DD5A 1B4AA 4C3HC 3AQPA 4KN7A 3H3VL 2PA8D 4A3BK 3TFJA 1ZXOA 3FOFA 3MMLB 2CFAA 1XPPA 4A3DK 3GTOK 1C0AA 1TWAC 1WCMK 1WORA 3WODA 2B63C 4A3CC 1IBAA 2Y0SL 2JA5A 4CKKA 2NVYA 3H0GC 3HKZD 1PJ6A 4WJ3M 3OPFA 1YX2A 2GAGC 2ZUEA 3GTKK 4Y7NC 2YU9K 5EGHA 4G7ZA 1K83K 1WIHA 3GTOA 4KMDA 4LOWA 1WCMA 3HOVK 1TWGK 3GTQK 3GTLK 2P5MA 1I50C 5CHPA 3PO3C 1O27A 4A3FC 4KMHA 4BY7K 3TFIA 1DCHA 3RZDC 4A3EK 3RZOK 4A93K 1GE9A 1O2AA 3GTPK 3GTKA 4MQ9A 3OREA 2RGRA 4Q4ZA 1KQ4A 1I3QK 4G0VA 2E2JC 1K83A 3K7AC 3GTMK 1IW7A 4QIWL 1TWGA 2A68A 2PPBA 3GTQA 3T00A 3GTLA 1I6HK 4Q5SA 4CKLA 3S1QK 3GTJK 3JSTA 5M3FK 1XXAA 4YFNA 3AD7C 3G4CA 3GTPA 4MEYA 1I3QA 3GTGK 3GIRA 1UV7A 4KARA 2CW0A 3S16C 4A3LC 4BY1C 3GTMA 1SFOA 2FQOA 3FKIC 3IPJA 2PA8L 5TMCA 4XLNA 3HOYK 4LQYA 3LAPA 3GTJA 1XZQB 1R9TK 4ZH4A 1Y1WK 2JA6C 1DCPA 3GTGA 1IL2A 3N3YA 2E2HC 2WB1L 4A3GC 4YG2A 3AQOA 1XXBA 2JA8K 1WOOA 5FLMK 2R93K 4XSZA 1IS1A 1R9TA 1Y1WA 3S15C 3HOUC 3HOXC 1TWAK 2NVQK 5D4DA 3S17C 3S1RC 1J6XA 1SMYA 3CQZK 2R93A 3BUEA 4A3KC 2V6SA 2WAQL 1WOPA 1JOEA 1ZBSA 1TWAA 3G4AA 1J6WA 3V4GA 1ZVUA 3GEHA 5IYDC 4ILDA 1I50K 1O28A 3BP8C 2P8TA 4A3FK 1F7UA 1ISEA 4KDDA 1EQRA 5IYCC 3CQZA 1USMA 4AYBD 3S2HC 4X6AK 1USOA 1XZPA 3LAJA 4YFXA 3LPXA 3S0XA 3K7AK 4OINA 1INNA 1HQMA 4LLGA 5C3EC 1I50A 2R92K 3S1MK 3M4OK 3HXAA 5IOTA 5IOSA 1X75A 4A3MK 4OIPA 4C2MK 1F7VA 5C4XC 4KM8A 1BJTA 4A3IC 2NVXC 4GTDA 3BP3A 1XXCA 1TWHK 4KB2A 2R92A 4C3IC 2ZUFA 4MEXA
chains in the Genus database with same CATH topology
4GTCA 4GFQA 4CKLA 4KM9A 1XXAA 4C3JC 4ELZA 3G4CA 1O24A 4GTLA 3GTPA 4G0WA 1TWHA 1WQFA 1I3QA 5JFEA 1O26A 4KARA 5CJ9A 3GTMA 1SFOA 1WQHA 1EH1A 4Z4QA 4LQYA 3LAPA 3GTJA 1O2BA 5IORA 4KAWX 2XCRB 1TWFA 2GSOA 3FOEA 4GTAA 3GTGA 4P5AA 3N3YA 2JA7A 3AQOA 1XXBA 3ERED 2GSUA 4GTEA 1WQGA 4M1XA 1BGWA 3FKIA 2R7ZA 4KMAA 5IOQA 1IS1A 1R9TA 2E2IA 4DDQA 4Z3OA 5JVOA 1Y1WA 2GSNA 2KWAA 4LR2A 1Y1VA 4FM9A 3AH5A 1AB4A 3L4KA 4G0UA 3QX3A 2XCQA 2JA6A 3VA7A 2PHCB 2CFAB 2E2HA 1DD5A 1B4AA 4C3HC 2R93A 3BUEA 3AQPA 5EGEA 1ZXOA 3FOFA 3MMLB 1ZBSA 1TWAA 2CFAA 3G4AA 1O29A 3V4GA 1ZVUA 4ILDA 2RH6A 1O28A 4KASA 3N0BA 2JA5A 2YU9A 4Z53A 4FZBA 4KATA 4CKKA 2NVYA 4P5BA 1ISEA 4KDDA 3CQZA 4GT9A 4BKWA 1F9NA 3OPFA 3LAJA 1TWCA 3S0XA 3LPXA 5TJ3A 5EGHA 2Y3PA 3Q3QA 1WIHA 3FHZA 3GTOA 3OEPA 4KMDA 4C2MC 1I50A 1WCMA 1B4BA 4ELYA 2P5MA 5CHPA 5IOTA 4KC6A 1X75A 5IOSA 1O27A 4KMHA 4J3NA 2NVXA 4BLAA 2JH3A 1EK8A 4KM8A 2B63A 1O25A 1BJTA 1GE9A 4GTDA 3L4JA 1O2AA 1XXCA 3H0GA 3GTKA 4KB2A 3OREA 2RGRA 1KQ4A 3CAGA 4G0VA 4GTFA 1K83A 2ZFZA 4KB4A 3N0CA 4TMAA 3NUHA 2R92A 2XCOA 4BLBA 1TWGA 4C3IC 2VUMA 3GTQA 3GTLA 4GTBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DD5 A;  2Y3P A;  4GFQ A;  4CKL A;  1B4A A;  1WIH A;  3FHZ A;  3BUE A;  3OEP A;  1XXA A;  4ELZ A;  1XXB A;  1B4B A;  3ERE D;  4ELY A;  3FOF A;  2P5M A;  3MML B;  4G0W A;  1WQG A;  1X75 A;  4KC6 A;  1WQF A;  3V4G A;  1ZVU A;  1BGW A;  4J3N A;  1EK8 A;  5CJ9 A;  1IS1 A;  4DDQ A;  1BJT A;  4Z3O A;  1WQH A;  1EH1 A;  5JVO A;  1GE9 A;  4Z4Q A;  3L4J A;  4Z53 A;  1XXC A;  2KWA A;  4CKK A;  3ORE A;  2RGR A;  1ISE A;  4KB2 A;  3CAG A;  4KDD A;  4G0V A;  3LAP A;  4FM9 A;  2ZFZ A;  4KB4 A;  1AB4 A;  3NUH A;  4TMA A;  2XCO A;  2XCR B;  3L4K A;  2XCQ A;  3QX3 A;  4G0U A;  1F9N A;  3OPF A;  4KAW X;  3LAJ A;  3FOE A;  3LPX A;  3VA7 A;  2PHC B; 
#chains in the Genus database with same CATH topology
 2VUM C;  2NVT K;  4PAA A;  1YCL A;  4KM9 A;  4C3J C;  5M3M K;  1TWF K;  2D6F C;  2JA7 C;  1O24 A;  3I4M C;  4G0W A;  1TWH A;  1IQ0 A;  3HOW C;  1WQF A;  2R7Z C;  3HOZ C;  4Z4Q A;  1VJE A;  2V6T A;  4OIO A;  3PO2 C;  3T01 A;  5C4J K;  1SFO K;  1TWF A;  2GSO A;  3S14 K;  5M5Y K;  4GTA A;  4CID A;  5TMF A;  4AYB L;  5C44 K;  3SZY A;  3ERE D;  4BBR C;  2GSU A;  2PMZ L;  1WSR A;  1RU0 A;  4GTE A;  4A3K K;  3M3Y C;  1BGW A;  4O2D A;  5IOQ A;  5IP9 K;  4DDQ A;  4Z3O A;  4Y52 C;  3S2D K;  2E2I C;  2O5J A;  2NVY C;  4FM9 A;  5IP7 K;  4G0U A;  3QX3 A;  2XCQ A;  1Y1V C;  4WIL A;  4OIR A;  3S1N K;  1F93 A;  2PHC B;  3VA7 A;  4A3B C;  3I4N C;  1L0W A;  3AD8 C;  4A3D C;  3A8K A;  3GTO C;  1XZQ A;  1PJ5 A;  3HKZ L;  1TWC K;  5C3E K;  4C3H K;  1EI6 A;  4G7O A;  1O29 A;  4KAS A;  2A69 A;  3N0B A;  4Z53 A;  2A6E A;  3GEI A;  2YU9 C;  2B63 K;  4A3C K;  1K83 C;  4KN4 A;  1TWC A;  3HOV C;  1TWG C;  3H0G K;  5IYB C;  3GTL C;  3GTQ C;  2Y3P A;  3Q3Q A;  3FHZ A;  1O2F B;  3OEP A;  3TTG A;  2Y0S D;  4BY7 C;  3ADA C;  2VUM K;  4Y7N K;  1VGX A;  3TFH A;  4ELY A;  4A3E C;  3RZO C;  4A93 C;  4KC6 A;  4C3J K;  2NVX A;  4BLA A;  2JH3 A;  1EK8 A;  4A3J C;  2B63 A;  4OIQ A;  4LK1 A;  3PO3 K;  1VH2 A;  3H0G A;  4WJ4 A;  3CAG A;  3RZD K;  1I6H C;  4BXX C;  4KB4 A;  3S1Q C;  3NUH A;  1VRQ C;  4BLB A;  2VUM A;  1WSV A;  2E2J K;  4GTC A;  1JQW A;  1V5V A;  3GTG C;  4BBS C;  5M5W K;  4GTL A;  1BDF A;  3HOY C;  1O26 A;  3A8I A;  4QIW D;  4BBR K;  5CJ9 A;  4YFK A;  1R9T C;  3S16 K;  4A3L K;  4BY1 K;  3FKI K;  5HL8 A;  4C45 A;  4KAW X;  4PAB A;  1J98 A;  4LJZ A;  2JA8 C;  5FLM C;  1Y1V K;  1EFW A;  1WOS A;  2R93 C;  2JA6 K;  3I4N K;  4RMF A;  1WQG A;  2E2H K;  4M1X A;  4A3G K;  3FKI A;  2NVQ C;  3A8J A;  2E2I A;  5JVO A;  3EQL A;  2WB1 D;  1Y1V A;  2FQT A;  3CQZ C;  1AB4 A;  3L4K A;  1BS2 A;  3S15 K;  3HOU K;  3HOX K;  4JK1 A;  2JA6 A;  4AH6 A;  2E2H A;  4QJV B;  3S17 K;  3S1R K;  5EGE A;  5IYB K;  5M5X K;  1JVI A;  3GEE A;  2W7V A;  4KMU A;  4QJV A;  4X6A C;  2RH6 A;  4G7H A;  4P9S A;  2YU9 A;  4A3J K;  4FZB A;  1J6V A;  4KAT A;  4P5B A;  5IYD K;  1YNJ A;  2JA5 C;  1X31 C;  4GT9 A;  4BKW A;  2WAQ D;  1F9N A;  2R92 C;  4BXX K;  5IYC K;  3S1M C;  3S2H K;  3M4O C;  5TJ3 A;  2BE5 A;  4A3M C;  5L46 A;  4C2M C;  2GAH C;  1ZQ1 C;  1B4B A;  1WCM C;  4BBS K;  4J3N A;  1TWH C;  1PJ7 A;  1O25 A;  3L4J A;  4XCH A;  3SZZ A;  5C4X K;  2EBB A;  4GTF A;  1G51 A;  4A3I K;  3H3V D;  2ZFZ A;  3GTK C;  2NVX K;  3N0C A;  4TMA A;  2NVT C;  2XCO A;  1HI9 A;  4GTB A;  1TWF C;  2O5I A;  5E68 A;  4GFQ A;  4LK0 A;  4C3I K;  1ZYR A;  4ELZ A;  3GSI A;  4XLP A;  5JFE A;  3GTP C;  4NOI A;  4GZY A;  2JA7 K;  1I3Q C;  1WQH A;  1EH1 A;  3I4M K;  5C4J C;  3HOW K;  3GTM C;  1SFO C;  3S14 C;  2A6H A;  1I6V A;  2R7Z K;  3HOZ K;  1O2B A;  5IOR A;  2XCR B;  5C44 C;  3GTJ C;  3GDZ A;  3FOE A;  5FJ8 K;  2V6U A;  3PO2 K;  4P5A A;  1YNN A;  1DCO A;  2JA7 A;  5IP9 C;  1VLO A;  1IE0 A;  3S2D C;  3AD9 C;  2R7Z A;  4KMA A;  1XZP B;  4XSX A;  5IP7 C;  2GSN A;  3M3Y K;  2KWA A;  3S1N C;  4LR2 A;  3T02 A;  1Y1W C;  3AH5 A;  3DXJ A;  2PMZ D;  4Y52 K;  2E2I K;  2QPT A;  2JA5 K;  2CFA B;  2NVY K;  1TWC C;  1DD5 A;  1B4A A;  4C3H C;  3AQP A;  4KN7 A;  3H3V L;  2PA8 D;  4A3B K;  3TFJ A;  1ZXO A;  3FOF A;  3MML B;  2CFA A;  1XPP A;  4A3D K;  3GTO K;  1C0A A;  1TWA C;  1WCM K;  1WOR A;  3WOD A;  2B63 C;  4A3C C;  1IBA A;  2Y0S L;  2JA5 A;  4CKK A;  2NVY A;  3H0G C;  3HKZ D;  1PJ6 A;  4WJ3 M;  3OPF A;  1YX2 A;  2GAG C;  2ZUE A;  3GTK K;  4Y7N C;  2YU9 K;  5EGH A;  4G7Z A;  1K83 K;  1WIH A;  3GTO A;  4KMD A;  4LOW A;  1WCM A;  3HOV K;  1TWG K;  3GTQ K;  3GTL K;  2P5M A;  1I50 C;  5CHP A;  3PO3 C;  1O27 A;  4A3F C;  4KMH A;  4BY7 K;  3TFI A;  1DCH A;  3RZD C;  4A3E K;  3RZO K;  4A93 K;  1GE9 A;  1O2A A;  3GTP K;  3GTK A;  4MQ9 A;  3ORE A;  2RGR A;  4Q4Z A;  1KQ4 A;  1I3Q K;  4G0V A;  2E2J C;  1K83 A;  3K7A C;  3GTM K;  1IW7 A;  4QIW L;  1TWG A;  2A68 A;  2PPB A;  3GTQ A;  3T00 A;  3GTL A;  1I6H K;  4Q5S A;  4CKL A;  3S1Q K;  3GTJ K;  3JST A;  5M3F K;  1XXA A;  4YFN A;  3AD7 C;  3G4C A;  3GTP A;  4MEY A;  1I3Q A;  3GTG K;  3GIR A;  1UV7 A;  4KAR A;  2CW0 A;  3S16 C;  4A3L C;  4BY1 C;  3GTM A;  1SFO A;  2FQO A;  3FKI C;  3IPJ A;  2PA8 L;  5TMC A;  4XLN A;  3HOY K;  4LQY A;  3LAP A;  3GTJ A;  1XZQ B;  1R9T K;  4ZH4 A;  1Y1W K;  2JA6 C;  1DCP A;  3GTG A;  1IL2 A;  3N3Y A;  2E2H C;  2WB1 L;  4A3G C;  4YG2 A;  3AQO A;  1XXB A;  2JA8 K;  1WOO A;  5FLM K;  2R93 K;  4XSZ A;  1IS1 A;  1R9T A;  1Y1W A;  3S15 C;  3HOU C;  3HOX C;  1TWA K;  2NVQ K;  5D4D A;  3S17 C;  3S1R C;  1J6X A;  1SMY A;  3CQZ K;  2R93 A;  3BUE A;  4A3K C;  2V6S A;  2WAQ L;  1WOP A;  1JOE A;  1ZBS A;  1TWA A;  3G4A A;  1J6W A;  3V4G A;  1ZVU A;  3GEH A;  5IYD C;  4ILD A;  1I50 K;  1O28 A;  3BP8 C;  2P8T A;  4A3F K;  1F7U A;  1ISE A;  4KDD A;  1EQR A;  5IYC C;  3CQZ A;  1USM A;  4AYB D;  3S2H C;  4X6A K;  1USO A;  1XZP A;  3LAJ A;  4YFX A;  3LPX A;  3S0X A;  3K7A K;  4OIN A;  1INN A;  1HQM A;  4LLG A;  5C3E C;  1I50 A;  2R92 K;  3S1M K;  3M4O K;  3HXA A;  5IOT A;  5IOS A;  1X75 A;  4A3M K;  4OIP A;  4C2M K;  1F7V A;  5C4X C;  4KM8 A;  1BJT A;  4A3I C;  2NVX C;  4GTD A;  3BP3 A;  1XXC A;  1TWH K;  4KB2 A;  2R92 A;  4C3I C;  2ZUF A;  4MEX A; 
#chains in the Genus database with same CATH homology
 4GTC A;  4GFQ A;  4CKL A;  4KM9 A;  1XXA A;  4C3J C;  4ELZ A;  3G4C A;  1O24 A;  4GTL A;  3GTP A;  4G0W A;  1TWH A;  1WQF A;  1I3Q A;  5JFE A;  1O26 A;  4KAR A;  5CJ9 A;  3GTM A;  1SFO A;  1WQH A;  1EH1 A;  4Z4Q A;  4LQY A;  3LAP A;  3GTJ A;  1O2B A;  5IOR A;  4KAW X;  2XCR B;  1TWF A;  2GSO A;  3FOE A;  4GTA A;  3GTG A;  4P5A A;  3N3Y A;  2JA7 A;  3AQO A;  1XXB A;  3ERE D;  2GSU A;  4GTE A;  1WQG A;  4M1X A;  1BGW A;  3FKI A;  2R7Z A;  4KMA A;  5IOQ A;  1IS1 A;  1R9T A;  2E2I A;  4DDQ A;  4Z3O A;  5JVO A;  1Y1W A;  2GSN A;  2KWA A;  4LR2 A;  1Y1V A;  4FM9 A;  3AH5 A;  1AB4 A;  3L4K A;  4G0U A;  3QX3 A;  2XCQ A;  2JA6 A;  3VA7 A;  2PHC B;  2CFA B;  2E2H A;  1DD5 A;  1B4A A;  4C3H C;  2R93 A;  3BUE A;  3AQP A;  5EGE A;  1ZXO A;  3FOF A;  3MML B;  1ZBS A;  1TWA A;  2CFA A;  3G4A A;  1O29 A;  3V4G A;  1ZVU A;  4ILD A;  2RH6 A;  1O28 A;  4KAS A;  3N0B A;  2JA5 A;  2YU9 A;  4Z53 A;  4FZB A;  4KAT A;  4CKK A;  2NVY A;  4P5B A;  1ISE A;  4KDD A;  3CQZ A;  4GT9 A;  4BKW A;  1F9N A;  3OPF A;  3LAJ A;  1TWC A;  3S0X A;  3LPX A;  5TJ3 A;  5EGH A;  2Y3P A;  3Q3Q A;  1WIH A;  3FHZ A;  3GTO A;  3OEP A;  4KMD A;  4C2M C;  1I50 A;  1WCM A;  1B4B A;  4ELY A;  2P5M A;  5CHP A;  5IOT A;  4KC6 A;  1X75 A;  5IOS A;  1O27 A;  4KMH A;  4J3N A;  2NVX A;  4BLA A;  2JH3 A;  1EK8 A;  4KM8 A;  2B63 A;  1O25 A;  1BJT A;  1GE9 A;  4GTD A;  3L4J A;  1O2A A;  1XXC A;  3H0G A;  3GTK A;  4KB2 A;  3ORE A;  2RGR A;  1KQ4 A;  3CAG A;  4G0V A;  4GTF A;  1K83 A;  2ZFZ A;  4KB4 A;  3N0C A;  4TMA A;  3NUH A;  2R92 A;  2XCO A;  4BLB A;  1TWG A;  4C3I C;  2VUM A;  3GTQ A;  3GTL A;  4GTB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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