1USOA

Dcoh, a bifunctional protein-binding transcriptional coactivator, pro9leu mutant
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
77
structure length
77
Chain Sequence
DWEERENPKRLVKTFAFPNFREALDFANRVGALAERENHHPRLTVEWGRVTVEWWTHSAGGVTEKDREMARLTDALL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords HEPATOCYTE NUCLEAR FACTOR 1-ALPHA
publication title Crystal Structure of Transcriptional Coactivator DCoH from Thermus Thermophilus
rcsb
source organism Thermus thermophilus
molecule tags Transcriptional stimulator
total genus 20
structure length 77
sequence length 77
chains with identical sequence B
ec nomenclature
pdb deposition date 2003-11-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01329 Pterin_4a Pterin 4 alpha carbinolamine dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1360.20 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 Transcriptional coactivator/pterin dehydratase 1usoA00
2EBBA 1DCHA 1DCOA 2V6UA 1DCPA 1USMA 1USOA 2V6SA 3JSTA 4C45A 4LOWA 4WILA 1F93A 1RU0A 2V6TA 3HXAA
chains in the Genus database with same CATH superfamily
4A3GK 1O24A 3ERED 2VUMC 3FKIK 3GTLC 3GTPK 1HI9A 1IBAA 3T00A 3OPFA 4BLAA 1TWFK 2O5IA 2JA6A 1XXCA 2R92C 3LPXA 3S0XA 1SFOK 2NVXK 2R7ZC 4P5BA 4PAAA 4GFQA 2XCQA 5IYCK 4BXXC 3T02A 3GTGC 1Y1VK 1WIHA 4BKWA 4P9SA 4Y7NK 1BDFA 4OIQA 1O29A 3TFHA 3PO2C 1ZXOA 2R93A 2E2IK 2RGRA 3K7AC 4XLNA 3S17C 4A3BC 2E2HA 2YU9A 1R9TA 2ZFZA 1I3QK 2JA8C 2NVTK 4BBSC 4G0WA 1KQ4A 4A3MC 1TWHC 4WILA 1TWCK 3FKIA 4A3EK 3GTPA 3HXAA 3GTKC 1DCPA 5C4XK 2WB1D 1ZQ1C 2Y3PA 1TWFA 1I50C 2WB1L 3I4MC 3HOZK 1INNA 2JA5A 5C3EK 5M3FK 1IS1A 2NVXA 1YCLA 4AYBL 3GTQC 2E2JC 4QIWD 3FHZA 1XZQA 2WAQD 4YFXA 1O27A 4KM8A 4QIWL 2WAQL 4A3DK 3A8KA 1YX2A 1Y1VA 4C2MK 1JVIA 1Y1WC 1O28A 4GTAA 2PA8D 1EQRA 5IYDK 1DCOA 2PA8L 2XCRB 3GTJC 4C3IC 3RZDK 1F9NA 2Y0SD 1O25A 1PJ6A 4P5AA 4BY7K 4A3IC 4C3HC 2Y0SL 1HQMA 5JVOA 1I3QA 3HOXK 4G7ZA 1EK8A 3S15C 2P5MA 4C3JK 4A3KK 2ZUFA 1TWCA 2JA7C 3S14K 1YNJA 3AH5A 3RZOK 5FLMC 4XCHA 4LOWA 1I6HK 2FQOA 3NUHA 3HOUC 4OIOA 1K83A 3H0GC 3GTLK 5IP9K 5EGEA 5IP7K 2B63K 4MEXA 3HKZD 2PHCB 3HOVC 3S1NC 5E68A 1J98A 4BY1K 3HKZL 3GTMA 3GTOA 2NVQC 3HOWC 3HOYK 5HL8A 1X31C 3S16C 3GEIA 3GTGK 2KWAA 1J6VA 5L46A 4G0UA 3TTGA 4GTDA 4A3FC 1TWAC 5C44K 4X6AK 1WCMK 3M3YC 3G4AA 3AQPA 3VA7A 1C0AA 3S1MC 1VH2A 3GIRA 3CAGA 2JA8K 1YNNA 2A6EA 4A93C 1IL2A 1O2FB 3S2HK 4G7OA 3S1QC 2B63A 1DCHA 1USOA 2NVYC 3I4MK 3S1RC 3DXJA 5IORA 4A3CC 4KATA 4KN7A 3WODA 3GTQK 4O2DA 2JA6C 4YG2A 3ADAC 1PJ7A 2XCOA 2V6SA 1XXBA 3M4OK 3L4JA 4LK0A 3SZZA 1WCMA 2V6UA 3PO3K 4C3IK 4A3LK 4LK1A 4C3HK 1B4BA 5IYBC 4A3JC 2R93C 3FOFA 4KASA 2JA7K 2E2HC 2YU9C 2P8TA 5FJ8K 1R9TC 1SFOA 4BBRC 4A3GC 1XPPA 3AD8C 3N3YA 3FKIC 4MQ9A 1ISEA 4KDDA 4G7HA 3GTPC 2W7VA 4WJ3M 3BP3A 1TWGK 4J3NA 3GDZA 1TWFC 1WOSA 1IQ0A 2FQTA 5EGHA 2JA5C 3I4NK 2E2IA 2NVXC 5CJ9A 3TFJA 5IYCC 1BGWA 4KC6A 4LR2A 4XLPA 1Y1VC 3FOEA 4Y7NC 1O2AA 2CFAA 3T01A 1UV7A 4KM9A 4KAWX 4FM9A 4FZBA 2GSUA 4DDQA 3S2DK 4A3FK 1AB4A 3GEEA 1TWAK 2PPBA 4KN4A 3CQZK 1F93A 2EBBA 3SZYA 1I3QC 2NVTC 3AD9C 4GZYA 2VUMK 1TWCC 1WORA 4A3EC 4YFKA 5C4XC 1TWGA 2CFAB 1F7UA 3HOZC 3GEHA 4KMHA 2R92K 2R7ZK 2CW0A 2GAHC 1IW7A 4LJZA 1K83C 4AH6A 4BXXK 4A3CK 1WOPA 4A3DC 5CHPA 1IE0A 5IOSA 1XZPA 1B4AA 3BUEA 4C2MC 1O2BA 4XSZA 3AD7C 3PO2K 3GTMC 3GTOC 1G51A 3N0BA 5IYDC 1WQHA 3EQLA 3K7AK 3S17K 4A3BK 3OEPA 3RZDC 3CQZA 4BY7C 1V5VA 3HOXC 4BBSK 3L4KA 2GSOA 4A3MK 1TWHK 3MMLB 4C3JC 4A3KC 3LAPA 2VUMA 1J6WA 2A69A 4OIRA 3GTLA 3GTKK 1USMA 3S14C 4NOIA 1EH1A 1XZPB 3RZOC 1I50K 1XXAA 4C45A 2R92A 2R7ZA 1I6HC 1WSRA 2V6TA 2E2JK 1EI6A 3JSTA 3IPJA 5IP9C 5IP7C 3GTGA 2B63C 3QX3A 4KMDA 1WSVA 3TFIA 4KARA 4BY1C 1JQWA 5TMCA 1Y1WK 1VJEA 2JA5K 1RU0A 3HOYC 2D6FC 1I6VA 3GTJK 4YFNA 4LQYA 4A3IK 4Y52C 3OREA 1J6XA 5IOQA 3S15K 1TWHA 4KMUA 3BP8C 1WOOA 4GTFA 1VRQC 3GTKA 3A8IA 5C44C 1PJ5A 4X6AC 1WCMC 1WQFA 1I50A 5M3MK 1VGXA 1ZBSA 5C4JC 5FLMK 4ZH4A 1O26A 5TJ3A 3LAJA 1BJTA 3GTQA 2BE5A 4GTEA 3HOUK 2A6HA 3S2HC 2O5JA 3H0GK 2GSNA 1ZVUA 1SMYA 4GTBA 3HOVK 3S1NK 1EFWA 1BS2A 4Q5SA 1SFOC 1JOEA 1Y1WA 2A68A 2ZUEA 3N0CA 2NVQK 4AYBD 4KB2A 4XSXA 3AQOA 3HOWK 3GTJA 1K83K 5TMFA 4KB4A 3S16K 1GE9A 4GTLA 4QJVA 4OINA 3G4CA 4BLBA 4PABA 2E2IC 1ZYRA 3GTMK 3M4OC 3V4GA 4KMAA 3GTOK 2JA7A 5JFEA 5IOTA 3M3YK 4GT9A 3PO3C 3S1MK 4ILDA 4A3LC 5D4DA 4A93K 1XZQB 3H3VD 3H0GA 3Q3QA 3S1QK 3H3VL 5M5XK 4QJVB 2NVYK 5C3EC 4JK1A 3S1RK 5M5YK 4M1XA 4GTCA 2JH3A 4MEYA 1VLOA 1TWGC 3A8JA 1F7VA 2PMZD 2JA6K 4OIPA 1DD5A 3I4NC 2PMZL 4G0VA 2RH6A 1TWAA 4WJ4A 4Q4ZA 4Y52K 2GAGC 5IYBK 3GSIA 4A3JK 4RMFA 2R93K 3S2DC 1WQGA 2E2HK 1L0WA 2YU9K 3CQZC 2NVYA 4LLGA 1R9TK 4BBRK 5M5WK 5C4JK
chains in the Genus database with same CATH topology
2EBBA 1DCHA 1DCOA 2V6UA 1DCPA 1USMA 1USOA 2V6SA 3JSTA 4C45A 4LOWA 4WILA 1F93A 1RU0A 2V6TA 3HXAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EBB A;  1DCH A;  1DCO A;  2V6U A;  1DCP A;  1USM A;  1USO A;  2V6S A;  3JST A;  4C45 A;  4LOW A;  4WIL A;  1F93 A;  1RU0 A;  2V6T A;  3HXA A; 
#chains in the Genus database with same CATH topology
 4A3G K;  1O24 A;  3ERE D;  2VUM C;  3FKI K;  3GTL C;  3GTP K;  1HI9 A;  1IBA A;  3T00 A;  3OPF A;  4BLA A;  1TWF K;  2O5I A;  2JA6 A;  1XXC A;  2R92 C;  3LPX A;  3S0X A;  1SFO K;  2NVX K;  2R7Z C;  4P5B A;  4PAA A;  4GFQ A;  2XCQ A;  5IYC K;  4BXX C;  3T02 A;  3GTG C;  1Y1V K;  1WIH A;  4BKW A;  4P9S A;  4Y7N K;  1BDF A;  4OIQ A;  1O29 A;  3TFH A;  3PO2 C;  1ZXO A;  2R93 A;  2E2I K;  2RGR A;  3K7A C;  4XLN A;  3S17 C;  4A3B C;  2E2H A;  2YU9 A;  1R9T A;  2ZFZ A;  1I3Q K;  2JA8 C;  2NVT K;  4BBS C;  4G0W A;  1KQ4 A;  4A3M C;  1TWH C;  4WIL A;  1TWC K;  3FKI A;  4A3E K;  3GTP A;  3HXA A;  3GTK C;  1DCP A;  5C4X K;  2WB1 D;  1ZQ1 C;  2Y3P A;  1TWF A;  1I50 C;  2WB1 L;  3I4M C;  3HOZ K;  1INN A;  2JA5 A;  5C3E K;  5M3F K;  1IS1 A;  2NVX A;  1YCL A;  4AYB L;  3GTQ C;  2E2J C;  4QIW D;  3FHZ A;  1XZQ A;  2WAQ D;  4YFX A;  1O27 A;  4KM8 A;  4QIW L;  2WAQ L;  4A3D K;  3A8K A;  1YX2 A;  1Y1V A;  4C2M K;  1JVI A;  1Y1W C;  1O28 A;  4GTA A;  2PA8 D;  1EQR A;  5IYD K;  1DCO A;  2PA8 L;  2XCR B;  3GTJ C;  4C3I C;  3RZD K;  1F9N A;  2Y0S D;  1O25 A;  1PJ6 A;  4P5A A;  4BY7 K;  4A3I C;  4C3H C;  2Y0S L;  1HQM A;  5JVO A;  1I3Q A;  3HOX K;  4G7Z A;  1EK8 A;  3S15 C;  2P5M A;  4C3J K;  4A3K K;  2ZUF A;  1TWC A;  2JA7 C;  3S14 K;  1YNJ A;  3AH5 A;  3RZO K;  5FLM C;  4XCH A;  4LOW A;  1I6H K;  2FQO A;  3NUH A;  3HOU C;  4OIO A;  1K83 A;  3H0G C;  3GTL K;  5IP9 K;  5EGE A;  5IP7 K;  2B63 K;  4MEX A;  3HKZ D;  2PHC B;  3HOV C;  3S1N C;  5E68 A;  1J98 A;  4BY1 K;  3HKZ L;  3GTM A;  3GTO A;  2NVQ C;  3HOW C;  3HOY K;  5HL8 A;  1X31 C;  3S16 C;  3GEI A;  3GTG K;  2KWA A;  1J6V A;  5L46 A;  4G0U A;  3TTG A;  4GTD A;  4A3F C;  1TWA C;  5C44 K;  4X6A K;  1WCM K;  3M3Y C;  3G4A A;  3AQP A;  3VA7 A;  1C0A A;  3S1M C;  1VH2 A;  3GIR A;  3CAG A;  2JA8 K;  1YNN A;  2A6E A;  4A93 C;  1IL2 A;  1O2F B;  3S2H K;  4G7O A;  3S1Q C;  2B63 A;  1DCH A;  1USO A;  2NVY C;  3I4M K;  3S1R C;  3DXJ A;  5IOR A;  4A3C C;  4KAT A;  4KN7 A;  3WOD A;  3GTQ K;  4O2D A;  2JA6 C;  4YG2 A;  3ADA C;  1PJ7 A;  2XCO A;  2V6S A;  1XXB A;  3M4O K;  3L4J A;  4LK0 A;  3SZZ A;  1WCM A;  2V6U A;  3PO3 K;  4C3I K;  4A3L K;  4LK1 A;  4C3H K;  1B4B A;  5IYB C;  4A3J C;  2R93 C;  3FOF A;  4KAS A;  2JA7 K;  2E2H C;  2YU9 C;  2P8T A;  5FJ8 K;  1R9T C;  1SFO A;  4BBR C;  4A3G C;  1XPP A;  3AD8 C;  3N3Y A;  3FKI C;  4MQ9 A;  1ISE A;  4KDD A;  4G7H A;  3GTP C;  2W7V A;  4WJ3 M;  3BP3 A;  1TWG K;  4J3N A;  3GDZ A;  1TWF C;  1WOS A;  1IQ0 A;  2FQT A;  5EGH A;  2JA5 C;  3I4N K;  2E2I A;  2NVX C;  5CJ9 A;  3TFJ A;  5IYC C;  1BGW A;  4KC6 A;  4LR2 A;  4XLP A;  1Y1V C;  3FOE A;  4Y7N C;  1O2A A;  2CFA A;  3T01 A;  1UV7 A;  4KM9 A;  4KAW X;  4FM9 A;  4FZB A;  2GSU A;  4DDQ A;  3S2D K;  4A3F K;  1AB4 A;  3GEE A;  1TWA K;  2PPB A;  4KN4 A;  3CQZ K;  1F93 A;  2EBB A;  3SZY A;  1I3Q C;  2NVT C;  3AD9 C;  4GZY A;  2VUM K;  1TWC C;  1WOR A;  4A3E C;  4YFK A;  5C4X C;  1TWG A;  2CFA B;  1F7U A;  3HOZ C;  3GEH A;  4KMH A;  2R92 K;  2R7Z K;  2CW0 A;  2GAH C;  1IW7 A;  4LJZ A;  1K83 C;  4AH6 A;  4BXX K;  4A3C K;  1WOP A;  4A3D C;  5CHP A;  1IE0 A;  5IOS A;  1XZP A;  1B4A A;  3BUE A;  4C2M C;  1O2B A;  4XSZ A;  3AD7 C;  3PO2 K;  3GTM C;  3GTO C;  1G51 A;  3N0B A;  5IYD C;  1WQH A;  3EQL A;  3K7A K;  3S17 K;  4A3B K;  3OEP A;  3RZD C;  3CQZ A;  4BY7 C;  1V5V A;  3HOX C;  4BBS K;  3L4K A;  2GSO A;  4A3M K;  1TWH K;  3MML B;  4C3J C;  4A3K C;  3LAP A;  2VUM A;  1J6W A;  2A69 A;  4OIR A;  3GTL A;  3GTK K;  1USM A;  3S14 C;  4NOI A;  1EH1 A;  1XZP B;  3RZO C;  1I50 K;  1XXA A;  4C45 A;  2R92 A;  2R7Z A;  1I6H C;  1WSR A;  2V6T A;  2E2J K;  1EI6 A;  3JST A;  3IPJ A;  5IP9 C;  5IP7 C;  3GTG A;  2B63 C;  3QX3 A;  4KMD A;  1WSV A;  3TFI A;  4KAR A;  4BY1 C;  1JQW A;  5TMC A;  1Y1W K;  1VJE A;  2JA5 K;  1RU0 A;  3HOY C;  2D6F C;  1I6V A;  3GTJ K;  4YFN A;  4LQY A;  4A3I K;  4Y52 C;  3ORE A;  1J6X A;  5IOQ A;  3S15 K;  1TWH A;  4KMU A;  3BP8 C;  1WOO A;  4GTF A;  1VRQ C;  3GTK A;  3A8I A;  5C44 C;  1PJ5 A;  4X6A C;  1WCM C;  1WQF A;  1I50 A;  5M3M K;  1VGX A;  1ZBS A;  5C4J C;  5FLM K;  4ZH4 A;  1O26 A;  5TJ3 A;  3LAJ A;  1BJT A;  3GTQ A;  2BE5 A;  4GTE A;  3HOU K;  2A6H A;  3S2H C;  2O5J A;  3H0G K;  2GSN A;  1ZVU A;  1SMY A;  4GTB A;  3HOV K;  3S1N K;  1EFW A;  1BS2 A;  4Q5S A;  1SFO C;  1JOE A;  1Y1W A;  2A68 A;  2ZUE A;  3N0C A;  2NVQ K;  4AYB D;  4KB2 A;  4XSX A;  3AQO A;  3HOW K;  3GTJ A;  1K83 K;  5TMF A;  4KB4 A;  3S16 K;  1GE9 A;  4GTL A;  4QJV A;  4OIN A;  3G4C A;  4BLB A;  4PAB A;  2E2I C;  1ZYR A;  3GTM K;  3M4O C;  3V4G A;  4KMA A;  3GTO K;  2JA7 A;  5JFE A;  5IOT A;  3M3Y K;  4GT9 A;  3PO3 C;  3S1M K;  4ILD A;  4A3L C;  5D4D A;  4A93 K;  1XZQ B;  3H3V D;  3H0G A;  3Q3Q A;  3S1Q K;  3H3V L;  5M5X K;  4QJV B;  2NVY K;  5C3E C;  4JK1 A;  3S1R K;  5M5Y K;  4M1X A;  4GTC A;  2JH3 A;  4MEY A;  1VLO A;  1TWG C;  3A8J A;  1F7V A;  2PMZ D;  2JA6 K;  4OIP A;  1DD5 A;  3I4N C;  2PMZ L;  4G0V A;  2RH6 A;  1TWA A;  4WJ4 A;  4Q4Z A;  4Y52 K;  2GAG C;  5IYB K;  3GSI A;  4A3J K;  4RMF A;  2R93 K;  3S2D C;  1WQG A;  2E2H K;  1L0W A;  2YU9 K;  3CQZ C;  2NVY A;  4LLG A;  1R9T K;  4BBR K;  5M5W K;  5C4J K; 
#chains in the Genus database with same CATH homology
 2EBB A;  1DCH A;  1DCO A;  2V6U A;  1DCP A;  1USM A;  1USO A;  2V6S A;  3JST A;  4C45 A;  4LOW A;  4WIL A;  1F93 A;  1RU0 A;  2V6T A;  3HXA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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