1USOA

Dcoh, a bifunctional protein-binding transcriptional coactivator, pro9leu mutant
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
77
structure length
77
Chain Sequence
DWEERENPKRLVKTFAFPNFREALDFANRVGALAERENHHPRLTVEWGRVTVEWWTHSAGGVTEKDREMARLTDALL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transcriptional stimulator
molecule keywords HEPATOCYTE NUCLEAR FACTOR 1-ALPHA
publication title Crystal Structure of Transcriptional Coactivator DCoH from Thermus Thermophilus
rcsb
source organism Thermus thermophilus
total genus 20
structure length 77
sequence length 77
chains with identical sequence B
ec nomenclature
pdb deposition date 2003-11-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01329 Pterin_4a Pterin 4 alpha carbinolamine dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1360.20 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 Transcriptional coactivator/pterin dehydratase 1usoA00
1RU0A 4C45A 3JSTA 1DCOA 4WILA 1DCPA 3HXAA 1USMA 2V6SA 1DCHA 1USOA 2V6UA 4LOWA 2V6TA 1F93A 2EBBA
chains in the Genus database with same CATH superfamily
1RU0A 1UV7A 3HOXC 3V4GA 3FOEA 3S1QK 1K83K 3GTGK 1ZVUA 4C3IC 3G4CA 2O5IA 3JSTA 1Y1VA 3I4NK 4Y7NK 4WILA 4GTDA 4GT9A 2WB1D 3S15K 4GTAA 3AD7C 1C0AA 2B63K 5D4DA 4KMUA 2PMZL 5EGHA 3PO2C 2O5JA 3S14C 4KN7A 3GTPK 1TWGC 4MQ9A 4PABA 5TMCA 3GTLK 3A8KA 5FLMC 1TWCA 1XZQA 4P5AA 3HOZK 4OIOA 4A93K 1BS2A 3LAJA 1KQ4A 3EQLA 4MEYA 4LOWA 5C3EC 1R9TK 1WORA 4XSXA 3HOYC 3VA7A 4FZBA 4X6AK 1DCHA 1YNNA 1WCMA 4C45A 3FOFA 4A3LC 1USMA 3T00A 4JK1A 1B4AA 3S0XA 4A3DC 1BDFA 2FQTA 4G7HA 3S1NC 4LR2A 4KMHA 4GTFA 4LLGA 2GAGC 5C4JK 3AQPA 3HOWK 2P5MA 4A3KC 4A3BK 4A3IC 4BY1C 4M1XA 4C3HK 1IBAA 1J6XA 3ADAC 2XCOA 1JVIA 4Y52K 5IYDK 3GEIA 3RZOK 4GTBA 5M5YK 1SFOK 4G7OA 1BGWA 2PMZD 2E2HA 2EBBA 2NVYK 1TWFC 4QJVA 5HL8A 1XXCA 4BLAA 3H0GK 5IORA 1BJTA 2V6UA 5IOTA 2JA5A 2WB1L 2E2IC 4XCHA 4NOIA 2JA8C 1I50C 3GTQC 3L4JA 4ZH4A 3TTGA 3CQZC 3GTOA 2BE5A 4A3GC 4Q4ZA 5C4XK 1I3QK 1YX2A 4KAWX 2VUMC 2NVQC 4OIPA 2ZUEA 4Q5SA 2JA7K 4A3CC 4BY7K 4AH6A 3GTJC 2VUMA 4PAAA 1XZQB 2P8TA 1J6WA 4A3EC 1I6HK 2GSNA 1Y1WC 3ERED 3GTJA 3S16K 2E2JC 5E68A 2YU9C 3S2DK 3PO3C 1TWAA 4KM8A 4BBRC 2A6EA 3S1MK 3I4MC 4RMFA 1O2AA 1IE0A 2YU9A 3HOXK 2JA6A 2Y0SD 2PA8D 3HXAA 3N0CA 5TMFA 3FKIC 2JH3A 2RGRA 2R7ZA 4J3NA 1DD5A 1VLOA 3FKIA 1Y1VC 4LQYA 3PO2K 2R93K 3S14K 1XZPA 3G4AA 2CFAA 1TWHC 1PJ7A 1TWGK 4KB2A 1O29A 5IYCC 1IQ0A 5FJ8K 1TWHA 4KARA 4A3FC 1F9NA 1HI9A 1TWCC 1F7VA 3HOYK 1I6VA 4BBSC 3OPFA 4KC6A 4QJVB 1ZBSA 4G0VA 3L4KA 3H3VL 3GTMK 4A3DK 1WCMC 3S1NK 4AYBD 3GTKK 2NVTC 4BKWA 1EK8A 1DCOA 4YFKA 3RZDC 1V5VA 4A3KK 4Y7NC 3A8IA 4A3IK 4P5BA 2NVXK 4KMDA 1K83A 1WSVA 3GTGA 4XLNA 1EI6A 2PHCB 5EGEA 3GTPC 1B4BA 1GE9A 1TWFK 2PA8L 2Y0SL 3N3YA 4QIWL 2B63A 2GSUA 3AD8C 3GTPA 2E2IK 4XSZA 2JA8K 4LK0A 4GZYA 4KMAA 1I50K 2E2HC 3GTLA 3GTQK 3HKZL 2ZUFA 1IL2A 3MMLB 3GIRA 3BP3A 3CQZK 4A3GK 3M3YK 4X6AC 2JA5C 1YNJA 2NVQK 3S17C 2R92K 1R9TA 1PJ5A 1XZPB 4A3CK 3GSIA 3GTOC 3H3VD 4OIQA 4G0WA 4A3EK 1VGXA 2V6TA 4GTEA 5C4JC 1Y1WK 1EH1A 2E2JK 3S2HC 1WSRA 3A8JA 2CW0A 4MEXA 3DXJA 3I4MK 2RH6A 1XXBA 4BXXK 3OEPA 3M4OC 3T02A 4C3HC 4YFXA 1TWAC 2A6HA 4AYBL 5C44K 4C2MC 5IP7K 5IP9C 2KWAA 1ZQ1C 1INNA 3BP8C 3BUEA 2JA6C 4C3JC 5CHPA 3HOUC 1Y1VK 2NVYC 3QX3A 4O2DA 5TJ3A 2R7ZC 3H0GC 1TWHK 4QIWD 1SFOA 4C3IK 3IPJA 1WIHA 2NVYA 5IYCK 4DDQA 4YG2A 3H0GA 2XCQA 4KB4A 3HKZD 1VJEA 4G0UA 4WJ4A 4A3JC 3HOVC 1O24A 1TWCK 4A3MC 3WODA 1I3QA 5FLMK 5IYBC 5M3FK 3K7AC 2JA7A 1I6HC 1WQHA 1WOPA 5M3MK 1WCMK 3S16C 4OIRA 3SZZA 5C3EK 3TFHA 2NVTK 1YCLA 1J98A 3GEEA 3GEHA 1VRQC 3FHZA 3RZDK 4FM9A 4A3LK 1XPPA 2PPBA 4GTLA 1F93A 3N0BA 3NUHA 4P9SA 1O27A 3TFJA 1XXAA 1ZXOA 3S1RC 2A68A 5M5XK 2R93C 3S1QC 5L46A 1K83C 1SMYA 5M5WK 3GTGC 3I4NC 2Y3PA 4KM9A 2R93A 1O28A 1VH2A 4BY1K 3S15C 1TWGA 1USOA 2E2HK 2B63C 2FQOA 4LJZA 2JA5K 3S17K 2WAQD 4KATA 3AD9C 3Q3QA 3GTLC 4LK1A 3HOZC 4GTCA 3GTOK 4A93C 2XCRB 3GTMC 4ILDA 4XLPA 1ZYRA 3GTKC 1R9TC 1O2FB 5JVOA 3GTMA 3S2HK 2VUMK 3GTKA 2V6SA 2CFAB 1X31C 1G51A 3GTJK 2GAHC 1L0WA 5CJ9A 3M4OK 2NVXC 1TWAK 1WQGA 4C2MK 4GFQA 1HQMA 5IP9K 1EQRA 2YU9K 3HOWC 2NVXA 2JA6K 3PO3K 4C3JK 4BBRK 3HOUK 3OREA 4YFNA 4KN4A 4A3BC 3GDZA 1ISEA 2R7ZK 1O26A 1IW7A 4G7ZA 3FKIK 3CAGA 1AB4A 1WOSA 1TWFA 3LAPA 4Y52C 5IYDC 3SZYA 3M3YC 3RZOC 2A69A 1SFOC 1PJ6A 2E2IA 4A3JK 3HOVK 1I50A 4KASA 1F7UA 3LPXA 2R92C 3GTQA 4A3MK 3CQZA 4BLBA 5IYBK 2R92A 3AQOA 2GSOA 3K7AK 1JQWA 5C4XC 1I3QC 3AH5A 3T01A 4A3FK 4KDDA 1J6VA 1O2BA 2W7VA 2WAQL 5IOSA 2JA7C 4BBSK 2ZFZA 1Y1WA 1WOOA 1WQFA 4BY7C 2D6FC 4BXXC 3TFIA 5IOQA 5C44C 1DCPA 5IP7C 4OINA 4WJ3M 1JOEA 1EFWA 3S2DC 1O25A 1IS1A 5JFEA 3S1RK 3S1MC
chains in the Genus database with same CATH topology
1RU0A 4C45A 3JSTA 1DCOA 4WILA 1DCPA 3HXAA 1USMA 2V6SA 1DCHA 1USOA 2V6UA 4LOWA 2V6TA 1F93A 2EBBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RU0 A;  4C45 A;  3JST A;  1DCO A;  4WIL A;  1DCP A;  3HXA A;  1USM A;  2V6S A;  1DCH A;  1USO A;  2V6U A;  4LOW A;  2V6T A;  1F93 A;  2EBB A; 
#chains in the Genus database with same CATH topology
 1RU0 A;  1UV7 A;  3HOX C;  3V4G A;  3FOE A;  3S1Q K;  1K83 K;  3GTG K;  1ZVU A;  4C3I C;  3G4C A;  2O5I A;  3JST A;  1Y1V A;  3I4N K;  4Y7N K;  4WIL A;  4GTD A;  4GT9 A;  2WB1 D;  3S15 K;  4GTA A;  3AD7 C;  1C0A A;  2B63 K;  5D4D A;  4KMU A;  2PMZ L;  5EGH A;  3PO2 C;  2O5J A;  3S14 C;  4KN7 A;  3GTP K;  1TWG C;  4MQ9 A;  4PAB A;  5TMC A;  3GTL K;  3A8K A;  5FLM C;  1TWC A;  1XZQ A;  4P5A A;  3HOZ K;  4OIO A;  4A93 K;  1BS2 A;  3LAJ A;  1KQ4 A;  3EQL A;  4MEY A;  4LOW A;  5C3E C;  1R9T K;  1WOR A;  4XSX A;  3HOY C;  3VA7 A;  4FZB A;  4X6A K;  1DCH A;  1YNN A;  1WCM A;  4C45 A;  3FOF A;  4A3L C;  1USM A;  3T00 A;  4JK1 A;  1B4A A;  3S0X A;  4A3D C;  1BDF A;  2FQT A;  4G7H A;  3S1N C;  4LR2 A;  4KMH A;  4GTF A;  4LLG A;  2GAG C;  5C4J K;  3AQP A;  3HOW K;  2P5M A;  4A3K C;  4A3B K;  4A3I C;  4BY1 C;  4M1X A;  4C3H K;  1IBA A;  1J6X A;  3ADA C;  2XCO A;  1JVI A;  4Y52 K;  5IYD K;  3GEI A;  3RZO K;  4GTB A;  5M5Y K;  1SFO K;  4G7O A;  1BGW A;  2PMZ D;  2E2H A;  2EBB A;  2NVY K;  1TWF C;  4QJV A;  5HL8 A;  1XXC A;  4BLA A;  3H0G K;  5IOR A;  1BJT A;  2V6U A;  5IOT A;  2JA5 A;  2WB1 L;  2E2I C;  4XCH A;  4NOI A;  2JA8 C;  1I50 C;  3GTQ C;  3L4J A;  4ZH4 A;  3TTG A;  3CQZ C;  3GTO A;  2BE5 A;  4A3G C;  4Q4Z A;  5C4X K;  1I3Q K;  1YX2 A;  4KAW X;  2VUM C;  2NVQ C;  4OIP A;  2ZUE A;  4Q5S A;  2JA7 K;  4A3C C;  4BY7 K;  4AH6 A;  3GTJ C;  2VUM A;  4PAA A;  1XZQ B;  2P8T A;  1J6W A;  4A3E C;  1I6H K;  2GSN A;  1Y1W C;  3ERE D;  3GTJ A;  3S16 K;  2E2J C;  5E68 A;  2YU9 C;  3S2D K;  3PO3 C;  1TWA A;  4KM8 A;  4BBR C;  2A6E A;  3S1M K;  3I4M C;  4RMF A;  1O2A A;  1IE0 A;  2YU9 A;  3HOX K;  2JA6 A;  2Y0S D;  2PA8 D;  3HXA A;  3N0C A;  5TMF A;  3FKI C;  2JH3 A;  2RGR A;  2R7Z A;  4J3N A;  1DD5 A;  1VLO A;  3FKI A;  1Y1V C;  4LQY A;  3PO2 K;  2R93 K;  3S14 K;  1XZP A;  3G4A A;  2CFA A;  1TWH C;  1PJ7 A;  1TWG K;  4KB2 A;  1O29 A;  5IYC C;  1IQ0 A;  5FJ8 K;  1TWH A;  4KAR A;  4A3F C;  1F9N A;  1HI9 A;  1TWC C;  1F7V A;  3HOY K;  1I6V A;  4BBS C;  3OPF A;  4KC6 A;  4QJV B;  1ZBS A;  4G0V A;  3L4K A;  3H3V L;  3GTM K;  4A3D K;  1WCM C;  3S1N K;  4AYB D;  3GTK K;  2NVT C;  4BKW A;  1EK8 A;  1DCO A;  4YFK A;  3RZD C;  1V5V A;  4A3K K;  4Y7N C;  3A8I A;  4A3I K;  4P5B A;  2NVX K;  4KMD A;  1K83 A;  1WSV A;  3GTG A;  4XLN A;  1EI6 A;  2PHC B;  5EGE A;  3GTP C;  1B4B A;  1GE9 A;  1TWF K;  2PA8 L;  2Y0S L;  3N3Y A;  4QIW L;  2B63 A;  2GSU A;  3AD8 C;  3GTP A;  2E2I K;  4XSZ A;  2JA8 K;  4LK0 A;  4GZY A;  4KMA A;  1I50 K;  2E2H C;  3GTL A;  3GTQ K;  3HKZ L;  2ZUF A;  1IL2 A;  3MML B;  3GIR A;  3BP3 A;  3CQZ K;  4A3G K;  3M3Y K;  4X6A C;  2JA5 C;  1YNJ A;  2NVQ K;  3S17 C;  2R92 K;  1R9T A;  1PJ5 A;  1XZP B;  4A3C K;  3GSI A;  3GTO C;  3H3V D;  4OIQ A;  4G0W A;  4A3E K;  1VGX A;  2V6T A;  4GTE A;  5C4J C;  1Y1W K;  1EH1 A;  2E2J K;  3S2H C;  1WSR A;  3A8J A;  2CW0 A;  4MEX A;  3DXJ A;  3I4M K;  2RH6 A;  1XXB A;  4BXX K;  3OEP A;  3M4O C;  3T02 A;  4C3H C;  4YFX A;  1TWA C;  2A6H A;  4AYB L;  5C44 K;  4C2M C;  5IP7 K;  5IP9 C;  2KWA A;  1ZQ1 C;  1INN A;  3BP8 C;  3BUE A;  2JA6 C;  4C3J C;  5CHP A;  3HOU C;  1Y1V K;  2NVY C;  3QX3 A;  4O2D A;  5TJ3 A;  2R7Z C;  3H0G C;  1TWH K;  4QIW D;  1SFO A;  4C3I K;  3IPJ A;  1WIH A;  2NVY A;  5IYC K;  4DDQ A;  4YG2 A;  3H0G A;  2XCQ A;  4KB4 A;  3HKZ D;  1VJE A;  4G0U A;  4WJ4 A;  4A3J C;  3HOV C;  1O24 A;  1TWC K;  4A3M C;  3WOD A;  1I3Q A;  5FLM K;  5IYB C;  5M3F K;  3K7A C;  2JA7 A;  1I6H C;  1WQH A;  1WOP A;  5M3M K;  1WCM K;  3S16 C;  4OIR A;  3SZZ A;  5C3E K;  3TFH A;  2NVT K;  1YCL A;  1J98 A;  3GEE A;  3GEH A;  1VRQ C;  3FHZ A;  3RZD K;  4FM9 A;  4A3L K;  1XPP A;  2PPB A;  4GTL A;  1F93 A;  3N0B A;  3NUH A;  4P9S A;  1O27 A;  3TFJ A;  1XXA A;  1ZXO A;  3S1R C;  2A68 A;  5M5X K;  2R93 C;  3S1Q C;  5L46 A;  1K83 C;  1SMY A;  5M5W K;  3GTG C;  3I4N C;  2Y3P A;  4KM9 A;  2R93 A;  1O28 A;  1VH2 A;  4BY1 K;  3S15 C;  1TWG A;  1USO A;  2E2H K;  2B63 C;  2FQO A;  4LJZ A;  2JA5 K;  3S17 K;  2WAQ D;  4KAT A;  3AD9 C;  3Q3Q A;  3GTL C;  4LK1 A;  3HOZ C;  4GTC A;  3GTO K;  4A93 C;  2XCR B;  3GTM C;  4ILD A;  4XLP A;  1ZYR A;  3GTK C;  1R9T C;  1O2F B;  5JVO A;  3GTM A;  3S2H K;  2VUM K;  3GTK A;  2V6S A;  2CFA B;  1X31 C;  1G51 A;  3GTJ K;  2GAH C;  1L0W A;  5CJ9 A;  3M4O K;  2NVX C;  1TWA K;  1WQG A;  4C2M K;  4GFQ A;  1HQM A;  5IP9 K;  1EQR A;  2YU9 K;  3HOW C;  2NVX A;  2JA6 K;  3PO3 K;  4C3J K;  4BBR K;  3HOU K;  3ORE A;  4YFN A;  4KN4 A;  4A3B C;  3GDZ A;  1ISE A;  2R7Z K;  1O26 A;  1IW7 A;  4G7Z A;  3FKI K;  3CAG A;  1AB4 A;  1WOS A;  1TWF A;  3LAP A;  4Y52 C;  5IYD C;  3SZY A;  3M3Y C;  3RZO C;  2A69 A;  1SFO C;  1PJ6 A;  2E2I A;  4A3J K;  3HOV K;  1I50 A;  4KAS A;  1F7U A;  3LPX A;  2R92 C;  3GTQ A;  4A3M K;  3CQZ A;  4BLB A;  5IYB K;  2R92 A;  3AQO A;  2GSO A;  3K7A K;  1JQW A;  5C4X C;  1I3Q C;  3AH5 A;  3T01 A;  4A3F K;  4KDD A;  1J6V A;  1O2B A;  2W7V A;  2WAQ L;  5IOS A;  2JA7 C;  4BBS K;  2ZFZ A;  1Y1W A;  1WOO A;  1WQF A;  4BY7 C;  2D6F C;  4BXX C;  3TFI A;  5IOQ A;  5C44 C;  1DCP A;  5IP7 C;  4OIN A;  4WJ3 M;  1JOE A;  1EFW A;  3S2D C;  1O25 A;  1IS1 A;  5JFE A;  3S1R K;  3S1M C; 
#chains in the Genus database with same CATH homology
 1RU0 A;  4C45 A;  3JST A;  1DCO A;  4WIL A;  1DCP A;  3HXA A;  1USM A;  2V6S A;  1DCH A;  1USO A;  2V6U A;  4LOW A;  2V6T A;  1F93 A;  2EBB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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