1USOA

Dcoh, a bifunctional protein-binding transcriptional coactivator, pro9leu mutant
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
77
structure length
77
Chain Sequence
DWEERENPKRLVKTFAFPNFREALDFANRVGALAERENHHPRLTVEWGRVTVEWWTHSAGGVTEKDREMARLTDALL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords HEPATOCYTE NUCLEAR FACTOR 1-ALPHA
publication title Crystal Structure of Transcriptional Coactivator DCoH from Thermus Thermophilus
rcsb
source organism Thermus thermophilus
molecule tags Transcriptional stimulator
total genus 20
structure length 77
sequence length 77
chains with identical sequence B
ec nomenclature
pdb deposition date 2003-11-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01329 Pterin_4a Pterin 4 alpha carbinolamine dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1360.20 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 Transcriptional coactivator/pterin dehydratase 1usoA00
4C45A 1USMA 4LOWA 2V6TA 2V6SA 2V6UA 2EBBA 3HXAA 4WILA 1DCHA 1DCOA 1DCPA 1RU0A 3JSTA 1USOA 1F93A
chains in the Genus database with same CATH superfamily
1VRQC 4PAAA 2GAGC 3S17K 1J6VA 4RMFA 3HOZK 1C0AA 4YFXA 3FOEA 3L4KA 4C2MK 1R9TC 2R93K 3I4MK 3HOYC 2E2IC 4A3IK 1XPPA 3GTJC 2NVQK 1O2BA 1SMYA 5FLMC 1I6VA 2GSOA 5L46A 1HQMA 3PO2K 1BJTA 1ZBSA 4QJVB 4AH6A 4MQ9A 4GTAA 4LR2A 4KDDA 3GTLK 4A3DC 1TWGC 3GIRA 4YFKA 4C3JK 2JA5C 3N3YA 3GTMA 2JA6A 2VUMC 1VGXA 4A3EC 2PHCB 3GTPK 2NVXC 3PO3C 1XZQB 4A93C 1YX2A 3AQOA 1ISEA 2NVYK 4GTEA 3OEPA 1R9TK 3S1NK 4BLAA 3JSTA 1XZPA 5TMCA 4GTLA 3GTKA 3GTJK 1O29A 3GTQA 1EH1A 3FKIC 4YFNA 1I3QA 1K83C 1O25A 4Q4ZA 3G4CA 3I4NC 4A3MC 1B4BA 2WB1L 4YG2A 3FHZA 1ZYRA 1TWHA 1USMA 1J6XA 2PA8D 4OIPA 4XLNA 4KMDA 4C3HC 2VUMK 4BY1C 1O2FB 2JA7A 1DCPA 3CQZA 4A3LK 3FOFA 2JA6K 3AD9C 5IYCC 2GSUA 2V6TA 2P8TA 4DDQA 2PMZL 2YU9K 1USOA 2E2HC 3S1QC 4GZYA 3BP8C 1TWAC 4C3IC 3GTKK 5E68A 1SFOA 1WQHA 1K83K 4BBSC 1F7VA 4A3JK 3I4NK 3SZYA 2A6EA 4A3BK 1PJ5A 1XZQA 4KASA 3H3VD 3GSIA 3HOZC 3S17C 4GT9A 3S0XA 2JH3A 4P5AA 4C2MC 1UV7A 2R93C 3I4MC 4QIWD 2R7ZC 4A3IC 2D6FC 4Y7NC 2NVQC 1VJEA 1XZPB 2E2JC 2E2HK 4FM9A 3S1QK 1Y1WK 3Q3QA 4GTFA 3GTOK 1IQ0A 5IP9K 3ADAC 4BBSK 5JFEA 1WCMK 1WIHA 5JVOA 2B63C 4A3GK 1I6HC 4LJZA 1SFOK 2ZUFA 3OREA 4G7OA 3S15K 3GTPC 4WJ4A 4A3CC 1O27A 3QX3A 5M5WK 5C44C 2NVYC 3LAPA 4G0UA 3S1NC 4AYBD 4Q5SA 2R7ZK 2V6SA 3H0GA 4Y7NK 3LAJA 3N0BA 1J6WA 5CHPA 1IW7A 2FQTA 2E2JK 4O2DA 1XXBA 1TWCA 1ZQ1C 3S16K 4KARA 1RU0A 2O5JA 2Y3PA 2B63K 4ILDA 4A3FK 1I6HK 1WOPA 4OIRA 1WORA 4MEYA 4G7ZA 1TWFA 2R92A 1L0WA 4A3CK 4A3LC 5FJ8K 2JA6C 5C44K 3S2HK 1TWGA 4NOIA 5IORA 1PJ7A 3A8JA 4XLPA 4A3KC 3HOWK 2A68A 2YU9C 2KWAA 1I50A 4KB4A 5IP7K 2NVXA 1IL2A 3GTKC 3H0GK 3WODA 4BXXC 4C45A 3HOUC 3M3YK 1ZXOA 4A3JC 1WSRA 1GE9A 3TFJA 4XCHA 3ERED 3S1MK 4LOWA 3HOXK 4A3BC 1DD5A 2XCRB 1JOEA 3S1RK 4X6AK 3FKIA 3HKZD 3GTMK 3BP3A 1DCHA 2Y0SD 4PABA 2CFAB 3LPXA 1TWFK 3T02A 3RZOK 1PJ6A 4OIQA 1IS1A 4LLGA 3TFHA 4A3KK 2FQOA 1BS2A 3A8IA 1Y1WC 3AQPA 3GTOC 4KAWX 2NVTK 3OPFA 2A69A 1Y1VA 4GTDA 3GTGA 4BXXK 5IP9C 2P5MA 4KATA 3GTQK 1WCMC 4A3GC 3N0CA 2A6HA 3HOUK 4LK0A 4G0VA 1IE0A 2CW0A 5M3FK 1I3QK 1SFOC 4BBRC 4KN4A 4ZH4A 1EFWA 1HI9A 2XCQA 3S15C 1EK8A 1O24A 1B4AA 1TWAA 2W7VA 1TWHK 3T01A 4P5BA 4KN7A 2RH6A 2JA7K 3CQZK 1EI6A 5TMFA 2PPBA 1WSVA 3S16C 4XSZA 2PA8L 4GTBA 3S2DK 3HKZL 4A3FC 1V5VA 1F93A 1BGWA 3GTGK 4P9SA 3K7AK 4BBRK 3L4JA 1INNA 2Y0SL 3M4OK 4GTCA 2RGRA 3T00A 2CFAA 4KM9A 3S2HC 3MMLB 1XXAA 3GTLA 5EGHA 5C3EC 1WOOA 5EGEA 4LQYA 5IOQA 1DCOA 3HOWC 3AD7C 4KMUA 3CAGA 5IP7C 3SZZA 3GTPA 3HOVK 2ZFZA 3H0GC 3G4AA 3NUHA 2NVYA 1KQ4A 5C4JK 1R9TA 2WB1D 3M3YC 2E2IA 1WQFA 1TWCC 4MEXA 3H3VL 1IBAA 5HL8A 3S1MC 3GTJA 3HOXC 3GEIA 4KMAA 4KB2A 3S1RC 3AH5A 4X6AC 4QIWL 5CJ9A 5M3MK 3GTMC 1TWFC 2R92C 5IYDC 3RZOC 5C3EK 2PMZD 2JA5A 5IOSA 1X31C 3VA7A 3TTGA 2VUMA 3S14K 1F7UA 1JVIA 3GEHA 5IOTA 3IPJA 4BY7K 1WOSA 2NVTC 5M5XK 1I50C 3GTQC 1VLOA 3RZDC 1TWCK 1I3QC 4J3NA 2YU9A 3HOYK 2E2IK 4AYBL 3AD8C 2WAQD 1BDFA 1J98A 1TWHC 2JA8C 1K83A 5FLMK 1YCLA 1VH2A 5IYBC 2R92K 5IYDK 2JA7C 4KMHA 3CQZC 1O26A 4A3DK 1TWGK 1YNNA 2O5IA 3GDZA 2JA5K 1AB4A 4JK1A 4A3EK 1I50K 2XCOA 2NVXK 3S2DC 1O28A 3PO3K 3RZDK 3TFIA 1JQWA 4A93K 1Y1VC 3GTGC 3K7AC 5C4XC 4WILA 2E2HA 3M4OC 1Y1WA 3GTOA 4FZBA 2V6UA 4BKWA 4WJ3M 4Y52C 5M5YK 2JA8K 1WCMA 3FKIK 5IYBK 4QJVA 3GEEA 3EQLA 2ZUEA 2EBBA 4G7HA 4GFQA 4M1XA 4G0WA 1F9NA 4A3MK 4BLBA 4LK1A 3HOVC 2GAHC 2BE5A 5C4JC 4C3HK 1XXCA 1ZVUA 4BY1K 2R93A 3HXAA 4OINA 2WAQL 3A8KA 2R7ZA 1YNJA 1Y1VK 5C4XK 4KM8A 5D4DA 5IYCK 2GSNA 1EQRA 3DXJA 4Y52K 3V4GA 2B63A 3PO2C 1TWAK 4C3IK 4KC6A 4OIOA 1O2AA 1WQGA 3GTLC 3S14C 5TJ3A 4XSXA 4C3JC 3BUEA 4BY7C 1G51A
chains in the Genus database with same CATH topology
4C45A 1USMA 4LOWA 2V6TA 2V6SA 2V6UA 2EBBA 3HXAA 4WILA 1DCHA 1DCOA 1DCPA 1RU0A 3JSTA 1USOA 1F93A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4C45 A;  1USM A;  4LOW A;  2V6T A;  2V6S A;  2V6U A;  2EBB A;  3HXA A;  4WIL A;  1DCH A;  1DCO A;  1DCP A;  1RU0 A;  3JST A;  1USO A;  1F93 A; 
#chains in the Genus database with same CATH topology
 1VRQ C;  4PAA A;  2GAG C;  3S17 K;  1J6V A;  4RMF A;  3HOZ K;  1C0A A;  4YFX A;  3FOE A;  3L4K A;  4C2M K;  1R9T C;  2R93 K;  3I4M K;  3HOY C;  2E2I C;  4A3I K;  1XPP A;  3GTJ C;  2NVQ K;  1O2B A;  1SMY A;  5FLM C;  1I6V A;  2GSO A;  5L46 A;  1HQM A;  3PO2 K;  1BJT A;  1ZBS A;  4QJV B;  4AH6 A;  4MQ9 A;  4GTA A;  4LR2 A;  4KDD A;  3GTL K;  4A3D C;  1TWG C;  3GIR A;  4YFK A;  4C3J K;  2JA5 C;  3N3Y A;  3GTM A;  2JA6 A;  2VUM C;  1VGX A;  4A3E C;  2PHC B;  3GTP K;  2NVX C;  3PO3 C;  1XZQ B;  4A93 C;  1YX2 A;  3AQO A;  1ISE A;  2NVY K;  4GTE A;  3OEP A;  1R9T K;  3S1N K;  4BLA A;  3JST A;  1XZP A;  5TMC A;  4GTL A;  3GTK A;  3GTJ K;  1O29 A;  3GTQ A;  1EH1 A;  3FKI C;  4YFN A;  1I3Q A;  1K83 C;  1O25 A;  4Q4Z A;  3G4C A;  3I4N C;  4A3M C;  1B4B A;  2WB1 L;  4YG2 A;  3FHZ A;  1ZYR A;  1TWH A;  1USM A;  1J6X A;  2PA8 D;  4OIP A;  4XLN A;  4KMD A;  4C3H C;  2VUM K;  4BY1 C;  1O2F B;  2JA7 A;  1DCP A;  3CQZ A;  4A3L K;  3FOF A;  2JA6 K;  3AD9 C;  5IYC C;  2GSU A;  2V6T A;  2P8T A;  4DDQ A;  2PMZ L;  2YU9 K;  1USO A;  2E2H C;  3S1Q C;  4GZY A;  3BP8 C;  1TWA C;  4C3I C;  3GTK K;  5E68 A;  1SFO A;  1WQH A;  1K83 K;  4BBS C;  1F7V A;  4A3J K;  3I4N K;  3SZY A;  2A6E A;  4A3B K;  1PJ5 A;  1XZQ A;  4KAS A;  3H3V D;  3GSI A;  3HOZ C;  3S17 C;  4GT9 A;  3S0X A;  2JH3 A;  4P5A A;  4C2M C;  1UV7 A;  2R93 C;  3I4M C;  4QIW D;  2R7Z C;  4A3I C;  2D6F C;  4Y7N C;  2NVQ C;  1VJE A;  1XZP B;  2E2J C;  2E2H K;  4FM9 A;  3S1Q K;  1Y1W K;  3Q3Q A;  4GTF A;  3GTO K;  1IQ0 A;  5IP9 K;  3ADA C;  4BBS K;  5JFE A;  1WCM K;  1WIH A;  5JVO A;  2B63 C;  4A3G K;  1I6H C;  4LJZ A;  1SFO K;  2ZUF A;  3ORE A;  4G7O A;  3S15 K;  3GTP C;  4WJ4 A;  4A3C C;  1O27 A;  3QX3 A;  5M5W K;  5C44 C;  2NVY C;  3LAP A;  4G0U A;  3S1N C;  4AYB D;  4Q5S A;  2R7Z K;  2V6S A;  3H0G A;  4Y7N K;  3LAJ A;  3N0B A;  1J6W A;  5CHP A;  1IW7 A;  2FQT A;  2E2J K;  4O2D A;  1XXB A;  1TWC A;  1ZQ1 C;  3S16 K;  4KAR A;  1RU0 A;  2O5J A;  2Y3P A;  2B63 K;  4ILD A;  4A3F K;  1I6H K;  1WOP A;  4OIR A;  1WOR A;  4MEY A;  4G7Z A;  1TWF A;  2R92 A;  1L0W A;  4A3C K;  4A3L C;  5FJ8 K;  2JA6 C;  5C44 K;  3S2H K;  1TWG A;  4NOI A;  5IOR A;  1PJ7 A;  3A8J A;  4XLP A;  4A3K C;  3HOW K;  2A68 A;  2YU9 C;  2KWA A;  1I50 A;  4KB4 A;  5IP7 K;  2NVX A;  1IL2 A;  3GTK C;  3H0G K;  3WOD A;  4BXX C;  4C45 A;  3HOU C;  3M3Y K;  1ZXO A;  4A3J C;  1WSR A;  1GE9 A;  3TFJ A;  4XCH A;  3ERE D;  3S1M K;  4LOW A;  3HOX K;  4A3B C;  1DD5 A;  2XCR B;  1JOE A;  3S1R K;  4X6A K;  3FKI A;  3HKZ D;  3GTM K;  3BP3 A;  1DCH A;  2Y0S D;  4PAB A;  2CFA B;  3LPX A;  1TWF K;  3T02 A;  3RZO K;  1PJ6 A;  4OIQ A;  1IS1 A;  4LLG A;  3TFH A;  4A3K K;  2FQO A;  1BS2 A;  3A8I A;  1Y1W C;  3AQP A;  3GTO C;  4KAW X;  2NVT K;  3OPF A;  2A69 A;  1Y1V A;  4GTD A;  3GTG A;  4BXX K;  5IP9 C;  2P5M A;  4KAT A;  3GTQ K;  1WCM C;  4A3G C;  3N0C A;  2A6H A;  3HOU K;  4LK0 A;  4G0V A;  1IE0 A;  2CW0 A;  5M3F K;  1I3Q K;  1SFO C;  4BBR C;  4KN4 A;  4ZH4 A;  1EFW A;  1HI9 A;  2XCQ A;  3S15 C;  1EK8 A;  1O24 A;  1B4A A;  1TWA A;  2W7V A;  1TWH K;  3T01 A;  4P5B A;  4KN7 A;  2RH6 A;  2JA7 K;  3CQZ K;  1EI6 A;  5TMF A;  2PPB A;  1WSV A;  3S16 C;  4XSZ A;  2PA8 L;  4GTB A;  3S2D K;  3HKZ L;  4A3F C;  1V5V A;  1F93 A;  1BGW A;  3GTG K;  4P9S A;  3K7A K;  4BBR K;  3L4J A;  1INN A;  2Y0S L;  3M4O K;  4GTC A;  2RGR A;  3T00 A;  2CFA A;  4KM9 A;  3S2H C;  3MML B;  1XXA A;  3GTL A;  5EGH A;  5C3E C;  1WOO A;  5EGE A;  4LQY A;  5IOQ A;  1DCO A;  3HOW C;  3AD7 C;  4KMU A;  3CAG A;  5IP7 C;  3SZZ A;  3GTP A;  3HOV K;  2ZFZ A;  3H0G C;  3G4A A;  3NUH A;  2NVY A;  1KQ4 A;  5C4J K;  1R9T A;  2WB1 D;  3M3Y C;  2E2I A;  1WQF A;  1TWC C;  4MEX A;  3H3V L;  1IBA A;  5HL8 A;  3S1M C;  3GTJ A;  3HOX C;  3GEI A;  4KMA A;  4KB2 A;  3S1R C;  3AH5 A;  4X6A C;  4QIW L;  5CJ9 A;  5M3M K;  3GTM C;  1TWF C;  2R92 C;  5IYD C;  3RZO C;  5C3E K;  2PMZ D;  2JA5 A;  5IOS A;  1X31 C;  3VA7 A;  3TTG A;  2VUM A;  3S14 K;  1F7U A;  1JVI A;  3GEH A;  5IOT A;  3IPJ A;  4BY7 K;  1WOS A;  2NVT C;  5M5X K;  1I50 C;  3GTQ C;  1VLO A;  3RZD C;  1TWC K;  1I3Q C;  4J3N A;  2YU9 A;  3HOY K;  2E2I K;  4AYB L;  3AD8 C;  2WAQ D;  1BDF A;  1J98 A;  1TWH C;  2JA8 C;  1K83 A;  5FLM K;  1YCL A;  1VH2 A;  5IYB C;  2R92 K;  5IYD K;  2JA7 C;  4KMH A;  3CQZ C;  1O26 A;  4A3D K;  1TWG K;  1YNN A;  2O5I A;  3GDZ A;  2JA5 K;  1AB4 A;  4JK1 A;  4A3E K;  1I50 K;  2XCO A;  2NVX K;  3S2D C;  1O28 A;  3PO3 K;  3RZD K;  3TFI A;  1JQW A;  4A93 K;  1Y1V C;  3GTG C;  3K7A C;  5C4X C;  4WIL A;  2E2H A;  3M4O C;  1Y1W A;  3GTO A;  4FZB A;  2V6U A;  4BKW A;  4WJ3 M;  4Y52 C;  5M5Y K;  2JA8 K;  1WCM A;  3FKI K;  5IYB K;  4QJV A;  3GEE A;  3EQL A;  2ZUE A;  2EBB A;  4G7H A;  4GFQ A;  4M1X A;  4G0W A;  1F9N A;  4A3M K;  4BLB A;  4LK1 A;  3HOV C;  2GAH C;  2BE5 A;  5C4J C;  4C3H K;  1XXC A;  1ZVU A;  4BY1 K;  2R93 A;  3HXA A;  4OIN A;  2WAQ L;  3A8K A;  2R7Z A;  1YNJ A;  1Y1V K;  5C4X K;  4KM8 A;  5D4D A;  5IYC K;  2GSN A;  1EQR A;  3DXJ A;  4Y52 K;  3V4G A;  2B63 A;  3PO2 C;  1TWA K;  4C3I K;  4KC6 A;  4OIO A;  1O2A A;  1WQG A;  3GTL C;  3S14 C;  5TJ3 A;  4XSX A;  4C3J C;  3BUE A;  4BY7 C;  1G51 A; 
#chains in the Genus database with same CATH homology
 4C45 A;  1USM A;  4LOW A;  2V6T A;  2V6S A;  2V6U A;  2EBB A;  3HXA A;  4WIL A;  1DCH A;  1DCO A;  1DCP A;  1RU0 A;  3JST A;  1USO A;  1F93 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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