1DCOA

Dcoh, a bifunctional protein-binding transcriptional coactivator
Total Genus 31
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
31
sequence length
99
structure length
99
Chain Sequence
HRLSAEERDQLLPNLRAVGWNELEGRDAIFKQFHFKDFNRAFGFMTRVALQAEKLDHHPEWFNVYNKVHITLSTHECAGLSERDINLASFIEQVAVSMT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title High-resolution structures of the bifunctional enzyme and transcriptional coactivator DCoH and its complex with a product analogue.
pubmed rcsb
molecule tags Transcriptional stimulator
source organism Rattus norvegicus
molecule keywords DCOH
total genus 31
structure length 99
sequence length 99
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 4.2.1.96: 4a-hydroxytetrahydrobiopterin dehydratase.
pdb deposition date 1996-05-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01329 Pterin_4a Pterin 4 alpha carbinolamine dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1360.20 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 Transcriptional coactivator/pterin dehydratase 1dcoA00
2V6SA 1USOA 1F93A 1DCPA 2V6TA 3HXAA 2V6UA 1USMA 3JSTA 1DCHA 4WILA 2EBBA 1RU0A 1DCOA 4C45A 4LOWA
chains in the Genus database with same CATH superfamily
4MQ9A 1O24A 2JA5A 3N3YA 3S1MC 4GT9A 1BGWA 3FOEA 2ZFZA 5C3EK 5M5YK 2CFAA 2WB1L 2P8TA 3OEPA 3TFJA 2PA8L 2GAGC 3HOUC 4AH6A 4A3CC 3S1RC 2E2HC 2FQTA 2KWAA 2PPBA 1VLOA 3G4AA 4KM9A 3RZDK 3H0GA 3S2DK 4XLPA 4OIQA 1I6HK 1TWHC 3A8IA 1IW7A 4A3IC 4G7HA 3M3YK 3OPFA 3I4NC 1GE9A 3S14C 1TWFA 1WOOA 1O26A 2V6UA 1ZXOA 5C4XK 4C3JC 4AYBD 2NVQC 1R9TK 3S1NK 1WQFA 2Y0SL 2RGRA 3RZOC 1J6XA 4GTEA 1F9NA 5JVOA 4KB4A 2V6SA 1VRQC 2ZUFA 4PABA 2E2IC 3M4OC 4A3GK 4QIWL 3HOXC 1TWAC 3S17C 1XXAA 2NVTK 3GTOA 1O2BA 4BBRC 2JA5K 2GSOA 4M1XA 1DCHA 4KC6A 1IBAA 4P5AA 5E68A 3IPJA 4A3LK 1TWGA 2PMZD 5C4JK 2NVXC 1F7VA 5IOQA 1USOA 4KMAA 4KMDA 2E2IA 2WAQL 3HOVC 2NVYK 1AB4A 3K7AK 2PHCB 1Y1WA 1O28A 4A3EC 1XZQA 2WB1D 4BBSC 3DXJA 2PA8D 1VJEA 3AQPA 2NVXA 1TWFK 2VUMC 2E2JC 4G7OA 3HOUK 1ZBSA 3HXAA 1IQ0A 4A3CK 1WQGA 3S1RK 3GTPC 1I50C 4RMFA 3HKZL 1WORA 4Q5SA 3AD7C 4QJVA 1TWHK 2A68A 4A3GC 4BXXC 3S16C 4A3FC 1JOEA 3H0GC 3S2HC 4KN7A 1O29A 3I4NK 1SFOC 3S14K 3GTGA 2VUMA 4C3HC 3GTOK 1I3QC 4C3JK 2JA8K 3AQOA 2O5JA 1X31C 5IORA 2NVQK 3N0CA 3T00A 4KM8A 3AH5A 3GIRA 2Y0SD 1TWGK 4A3BK 4C2MC 5JFEA 3AD9C 2E2IK 2R93A 3M4OK 1F7UA 1XZPB 3HOXK 1SFOA 2GSUA 3BP3A 5M3FK 1TWAK 3S17K 1I3QA 4BBRK 4GTFA 4A3DC 4LJZA 1TWFC 2XCOA 1KQ4A 2XCQA 3JSTA 2JH3A 2NVXK 2R7ZA 3BUEA 4MEYA 2D6FC 4BY1C 4XSXA 3HOVK 4LR2A 4A3JK 1IS1A 1VH2A 1SMYA 5M5WK 1XPPA 4A3EK 1ZQ1C 4KASA 3GTLC 4BBSK 2JA6A 1K83A 5C44C 2EBBA 3GTOC 4KARA 2JA8C 2JA7C 3GTQA 2VUMK 3S1QC 2E2JK 1HQMA 1WCMA 1O2AA 3HKZD 3GTPK 1I50K 3TTGA 4XSZA 1TWGC 4Y7NK 2V6TA 4A3BC 1HI9A 1EQRA 3WODA 3LPXA 3AD8C 3FOFA 4BXXK 2B63A 3S16K 4A3FK 4LLGA 3H0GK 1EK8A 2Y3PA 3S2HK 3GTLA 4P5BA 1Y1WC 3S0XA 1SFOK 2JA7A 4C3HK 1XXCA 1I3QK 4C3IC 1TWCC 1G51A 3A8KA 1XXBA 3I4MC 4C2MK 3HOZK 4LK1A 3HOYK 4JK1A 2YU9A 4A3JC 4BLAA 1J98A 3H3VL 4KB2A 5D4DA 5FJ8K 2A69A 2CFAB 4A3DK 4KAWX 3GTGC 2JA6K 1TWCA 3TFHA 1VGXA 4FZBA 1DCOA 3T02A 4YG2A 4GTCA 4Y7NC 3GTJC 2GAHC 4A3KC 1YNJA 4LQYA 3VA7A 1YX2A 4Y52C 3FHZA 4BY1K 3ADAC 2R92C 3ERED 1O25A 1EI6A 4YFNA 4WJ4A 3CQZC 3PO3C 2R93C 2B63K 3GTLK 2FQOA 4AYBL 5C44K 5TMFA 2JA7K 4GTLA 5TMCA 3S1QK 3GTJA 4OINA 4G7ZA 4GFQA 1ZYRA 4KN4A 2R92A 2R7ZC 4BKWA 3HOZC 1C0AA 1ISEA 3CQZA 3HOYC 4QIWD 4BY7K 5TJ3A 1PJ5A 4KATA 3V4GA 1ZVUA 1EH1A 1O2FB 4ZH4A 4NOIA 5FLMK 1Y1WK 5IP7C 3GEHA 3TFIA 1Y1VA 3LAJA 4XCHA 3L4KA 3GSIA 2O5IA 2JA6C 1K83C 3GTQC 4J3NA 4C3IK 3SZZA 1J6VA 1TWCK 4G0UA 3GTMC 3NUHA 3GTKC 1WCMC 4DDQA 5M3MK 2WAQD 4ILDA 3I4MK 4YFKA 4YFXA 3GEIA 4A3MC 4MEXA 3S15C 1DCPA 3H3VD 5IYCC 4FM9A 4G0VA 4PAAA 1B4AA 1RU0A 2A6EA 4GTAA 2B63C 4KDDA 1XZQB 3LAPA 3GTGK 3GTMA 4X6AC 3GTKA 2NVYA 5L46A 4O2DA 3Q3QA 3GTJK 1DD5A 4A3KK 5IP9C 1BDFA 4Y52K 4QJVB 2R92K 5IYDC 4BY7C 2W7VA 4GTDA 3CQZK 4A93C 2YU9C 2XCRB 3PO3K 2R93K 1WIHA 5FLMC 3N0BA 2P5MA 2E2HA 5CJ9A 1EFWA 2GSNA 3A8JA 3PO2C 3T01A 3FKIC 1TWHA 1Y1VK 1WOSA 4OIRA 2R7ZK 3G4CA 1XZPA 4LK0A 1YNNA 3EQLA 1B4BA 5C3EC 3SZYA 2BE5A 3CAGA 1V5VA 5IP7K 3FKIA 5IOTA 1BS2A 4KMUA 1K83K 1USMA 3QX3A 3RZDC 3GTQK 3S2DC 1WSVA 1I6HC 1F93A 5IYBK 3GTMK 5CHPA 3GTKK 1WCMK 2CW0A 3M3YC 1INNA 3HOWK 1TWAA 4A3MK 3S15K 4OIPA 4G0WA 2RH6A 1PJ6A 3S1MK 1WOPA 1YCLA 5IYCK 5M5XK 5C4XC 4BLBA 4WILA 1PJ7A 3BP8C 1R9TC 3S1NC 4WJ3M 2E2HK 1JVIA 1JQWA 4XLNA 4KMHA 4X6AK 1Y1VC 4Q4ZA 4C45A 1BJTA 5IOSA 4A3IK 3MMLB 1O27A 5IP9K 1I6VA 1UV7A 5IYDK 2NVTC 4GZYA 4OIOA 2JA5C 2A6HA 4A93K 5EGHA 1R9TA 2YU9K 5HL8A 1WSRA 3L4JA 3GTPA 1I50A 4A3LC 3GEEA 4LOWA 3OREA 5C4JC 1IL2A 1L0WA 3PO2K 3GDZA 2PMZL 2ZUEA 3FKIK 5EGEA 1WQHA 5IYBC 3RZOK 2NVYC 1IE0A 3HOWC 4GTBA 4P9SA 1J6WA 3K7AC
chains in the Genus database with same CATH topology
2V6SA 1USOA 1F93A 1DCPA 2V6TA 3HXAA 2V6UA 1USMA 3JSTA 1DCHA 4WILA 2EBBA 1RU0A 1DCOA 4C45A 4LOWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2V6S A;  1USO A;  1F93 A;  1DCP A;  2V6T A;  3HXA A;  2V6U A;  1USM A;  3JST A;  1DCH A;  4WIL A;  2EBB A;  1RU0 A;  1DCO A;  4C45 A;  4LOW A; 
#chains in the Genus database with same CATH topology
 4MQ9 A;  1O24 A;  2JA5 A;  3N3Y A;  3S1M C;  4GT9 A;  1BGW A;  3FOE A;  2ZFZ A;  5C3E K;  5M5Y K;  2CFA A;  2WB1 L;  2P8T A;  3OEP A;  3TFJ A;  2PA8 L;  2GAG C;  3HOU C;  4AH6 A;  4A3C C;  3S1R C;  2E2H C;  2FQT A;  2KWA A;  2PPB A;  1VLO A;  3G4A A;  4KM9 A;  3RZD K;  3H0G A;  3S2D K;  4XLP A;  4OIQ A;  1I6H K;  1TWH C;  3A8I A;  1IW7 A;  4A3I C;  4G7H A;  3M3Y K;  3OPF A;  3I4N C;  1GE9 A;  3S14 C;  1TWF A;  1WOO A;  1O26 A;  2V6U A;  1ZXO A;  5C4X K;  4C3J C;  4AYB D;  2NVQ C;  1R9T K;  3S1N K;  1WQF A;  2Y0S L;  2RGR A;  3RZO C;  1J6X A;  4GTE A;  1F9N A;  5JVO A;  4KB4 A;  2V6S A;  1VRQ C;  2ZUF A;  4PAB A;  2E2I C;  3M4O C;  4A3G K;  4QIW L;  3HOX C;  1TWA C;  3S17 C;  1XXA A;  2NVT K;  3GTO A;  1O2B A;  4BBR C;  2JA5 K;  2GSO A;  4M1X A;  1DCH A;  4KC6 A;  1IBA A;  4P5A A;  5E68 A;  3IPJ A;  4A3L K;  1TWG A;  2PMZ D;  5C4J K;  2NVX C;  1F7V A;  5IOQ A;  1USO A;  4KMA A;  4KMD A;  2E2I A;  2WAQ L;  3HOV C;  2NVY K;  1AB4 A;  3K7A K;  2PHC B;  1Y1W A;  1O28 A;  4A3E C;  1XZQ A;  2WB1 D;  4BBS C;  3DXJ A;  2PA8 D;  1VJE A;  3AQP A;  2NVX A;  1TWF K;  2VUM C;  2E2J C;  4G7O A;  3HOU K;  1ZBS A;  3HXA A;  1IQ0 A;  4A3C K;  1WQG A;  3S1R K;  3GTP C;  1I50 C;  4RMF A;  3HKZ L;  1WOR A;  4Q5S A;  3AD7 C;  4QJV A;  1TWH K;  2A68 A;  4A3G C;  4BXX C;  3S16 C;  4A3F C;  1JOE A;  3H0G C;  3S2H C;  4KN7 A;  1O29 A;  3I4N K;  1SFO C;  3S14 K;  3GTG A;  2VUM A;  4C3H C;  3GTO K;  1I3Q C;  4C3J K;  2JA8 K;  3AQO A;  2O5J A;  1X31 C;  5IOR A;  2NVQ K;  3N0C A;  3T00 A;  4KM8 A;  3AH5 A;  3GIR A;  2Y0S D;  1TWG K;  4A3B K;  4C2M C;  5JFE A;  3AD9 C;  2E2I K;  2R93 A;  3M4O K;  1F7U A;  1XZP B;  3HOX K;  1SFO A;  2GSU A;  3BP3 A;  5M3F K;  1TWA K;  3S17 K;  1I3Q A;  4BBR K;  4GTF A;  4A3D C;  4LJZ A;  1TWF C;  2XCO A;  1KQ4 A;  2XCQ A;  3JST A;  2JH3 A;  2NVX K;  2R7Z A;  3BUE A;  4MEY A;  2D6F C;  4BY1 C;  4XSX A;  3HOV K;  4LR2 A;  4A3J K;  1IS1 A;  1VH2 A;  1SMY A;  5M5W K;  1XPP A;  4A3E K;  1ZQ1 C;  4KAS A;  3GTL C;  4BBS K;  2JA6 A;  1K83 A;  5C44 C;  2EBB A;  3GTO C;  4KAR A;  2JA8 C;  2JA7 C;  3GTQ A;  2VUM K;  3S1Q C;  2E2J K;  1HQM A;  1WCM A;  1O2A A;  3HKZ D;  3GTP K;  1I50 K;  3TTG A;  4XSZ A;  1TWG C;  4Y7N K;  2V6T A;  4A3B C;  1HI9 A;  1EQR A;  3WOD A;  3LPX A;  3AD8 C;  3FOF A;  4BXX K;  2B63 A;  3S16 K;  4A3F K;  4LLG A;  3H0G K;  1EK8 A;  2Y3P A;  3S2H K;  3GTL A;  4P5B A;  1Y1W C;  3S0X A;  1SFO K;  2JA7 A;  4C3H K;  1XXC A;  1I3Q K;  4C3I C;  1TWC C;  1G51 A;  3A8K A;  1XXB A;  3I4M C;  4C2M K;  3HOZ K;  4LK1 A;  3HOY K;  4JK1 A;  2YU9 A;  4A3J C;  4BLA A;  1J98 A;  3H3V L;  4KB2 A;  5D4D A;  5FJ8 K;  2A69 A;  2CFA B;  4A3D K;  4KAW X;  3GTG C;  2JA6 K;  1TWC A;  3TFH A;  1VGX A;  4FZB A;  1DCO A;  3T02 A;  4YG2 A;  4GTC A;  4Y7N C;  3GTJ C;  2GAH C;  4A3K C;  1YNJ A;  4LQY A;  3VA7 A;  1YX2 A;  4Y52 C;  3FHZ A;  4BY1 K;  3ADA C;  2R92 C;  3ERE D;  1O25 A;  1EI6 A;  4YFN A;  4WJ4 A;  3CQZ C;  3PO3 C;  2R93 C;  2B63 K;  3GTL K;  2FQO A;  4AYB L;  5C44 K;  5TMF A;  2JA7 K;  4GTL A;  5TMC A;  3S1Q K;  3GTJ A;  4OIN A;  4G7Z A;  4GFQ A;  1ZYR A;  4KN4 A;  2R92 A;  2R7Z C;  4BKW A;  3HOZ C;  1C0A A;  1ISE A;  3CQZ A;  3HOY C;  4QIW D;  4BY7 K;  5TJ3 A;  1PJ5 A;  4KAT A;  3V4G A;  1ZVU A;  1EH1 A;  1O2F B;  4ZH4 A;  4NOI A;  5FLM K;  1Y1W K;  5IP7 C;  3GEH A;  3TFI A;  1Y1V A;  3LAJ A;  4XCH A;  3L4K A;  3GSI A;  2O5I A;  2JA6 C;  1K83 C;  3GTQ C;  4J3N A;  4C3I K;  3SZZ A;  1J6V A;  1TWC K;  4G0U A;  3GTM C;  3NUH A;  3GTK C;  1WCM C;  4DDQ A;  5M3M K;  2WAQ D;  4ILD A;  3I4M K;  4YFK A;  4YFX A;  3GEI A;  4A3M C;  4MEX A;  3S15 C;  1DCP A;  3H3V D;  5IYC C;  4FM9 A;  4G0V A;  4PAA A;  1B4A A;  1RU0 A;  2A6E A;  4GTA A;  2B63 C;  4KDD A;  1XZQ B;  3LAP A;  3GTG K;  3GTM A;  4X6A C;  3GTK A;  2NVY A;  5L46 A;  4O2D A;  3Q3Q A;  3GTJ K;  1DD5 A;  4A3K K;  5IP9 C;  1BDF A;  4Y52 K;  4QJV B;  2R92 K;  5IYD C;  4BY7 C;  2W7V A;  4GTD A;  3CQZ K;  4A93 C;  2YU9 C;  2XCR B;  3PO3 K;  2R93 K;  1WIH A;  5FLM C;  3N0B A;  2P5M A;  2E2H A;  5CJ9 A;  1EFW A;  2GSN A;  3A8J A;  3PO2 C;  3T01 A;  3FKI C;  1TWH A;  1Y1V K;  1WOS A;  4OIR A;  2R7Z K;  3G4C A;  1XZP A;  4LK0 A;  1YNN A;  3EQL A;  1B4B A;  5C3E C;  3SZY A;  2BE5 A;  3CAG A;  1V5V A;  5IP7 K;  3FKI A;  5IOT A;  1BS2 A;  4KMU A;  1K83 K;  1USM A;  3QX3 A;  3RZD C;  3GTQ K;  3S2D C;  1WSV A;  1I6H C;  1F93 A;  5IYB K;  3GTM K;  5CHP A;  3GTK K;  1WCM K;  2CW0 A;  3M3Y C;  1INN A;  3HOW K;  1TWA A;  4A3M K;  3S15 K;  4OIP A;  4G0W A;  2RH6 A;  1PJ6 A;  3S1M K;  1WOP A;  1YCL A;  5IYC K;  5M5X K;  5C4X C;  4BLB A;  4WIL A;  1PJ7 A;  3BP8 C;  1R9T C;  3S1N C;  4WJ3 M;  2E2H K;  1JVI A;  1JQW A;  4XLN A;  4KMH A;  4X6A K;  1Y1V C;  4Q4Z A;  4C45 A;  1BJT A;  5IOS A;  4A3I K;  3MML B;  1O27 A;  5IP9 K;  1I6V A;  1UV7 A;  5IYD K;  2NVT C;  4GZY A;  4OIO A;  2JA5 C;  2A6H A;  4A93 K;  5EGH A;  1R9T A;  2YU9 K;  5HL8 A;  1WSR A;  3L4J A;  3GTP A;  1I50 A;  4A3L C;  3GEE A;  4LOW A;  3ORE A;  5C4J C;  1IL2 A;  1L0W A;  3PO2 K;  3GDZ A;  2PMZ L;  2ZUE A;  3FKI K;  5EGE A;  1WQH A;  5IYB C;  3RZO K;  2NVY C;  1IE0 A;  3HOW C;  4GTB A;  4P9S A;  1J6W A;  3K7A C; 
#chains in the Genus database with same CATH homology
 2V6S A;  1USO A;  1F93 A;  1DCP A;  2V6T A;  3HXA A;  2V6U A;  1USM A;  3JST A;  1DCH A;  4WIL A;  2EBB A;  1RU0 A;  1DCO A;  4C45 A;  4LOW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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