1DCOA

Dcoh, a bifunctional protein-binding transcriptional coactivator
Total Genus 31
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
31
sequence length
99
structure length
99
Chain Sequence
HRLSAEERDQLLPNLRAVGWNELEGRDAIFKQFHFKDFNRAFGFMTRVALQAEKLDHHPEWFNVYNKVHITLSTHECAGLSERDINLASFIEQVAVSMT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title High-resolution structures of the bifunctional enzyme and transcriptional coactivator DCoH and its complex with a product analogue.
pubmed rcsb
molecule tags Transcriptional stimulator
source organism Rattus norvegicus
molecule keywords DCOH
total genus 31
structure length 99
sequence length 99
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 4.2.1.96: 4a-hydroxytetrahydrobiopterin dehydratase.
pdb deposition date 1996-05-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01329 Pterin_4a Pterin 4 alpha carbinolamine dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1360.20 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 Transcriptional coactivator/pterin dehydratase 1dcoA00
1USOA 2V6UA 1F93A 4WILA 1USMA 3JSTA 2V6TA 1DCPA 2V6SA 1DCOA 1DCHA 4LOWA 4C45A 1RU0A 2EBBA 3HXAA
chains in the Genus database with same CATH superfamily
3GIRA 1F93A 4JK1A 4KMDA 1VLOA 4KM8A 4AH6A 3I4MK 3IPJA 3PO3C 3TFIA 3S14K 4BBRK 2R93C 2E2IK 1O26A 2GSOA 2VUMK 3S1NC 1I50K 1WCMC 1R9TA 2PMZD 1TWHK 4G7OA 2P8TA 4MQ9A 1F7UA 4A3DK 2RGRA 5C4XC 5TMFA 2Y0SD 2D6FC 3MMLB 4A93K 4P5AA 4BLBA 3HOVK 4G7ZA 4LQYA 1TWCK 4X6AK 2JA6K 4Y7NK 3N0CA 1I3QA 5IYBC 1V5VA 3M4OC 4YFKA 1TWAC 2V6UA 3T01A 2YU9A 4G7HA 3GTKC 1XZPA 1KQ4A 2WB1D 4GTAA 5IORA 2A69A 2ZUEA 3ERED 1ZVUA 5FLMK 2PA8D 3HOUC 1ISEA 3GTJK 3T00A 1K83C 5M3FK 4QJVA 2R93A 1TWGA 3HOYC 2ZFZA 5EGHA 3CQZK 4A3KK 3M3YC 3LAPA 4A3FC 1WOPA 3BUEA 4FM9A 3RZDC 1B4AA 3S17C 4MEXA 2NVYK 4J3NA 2NVXK 4GTCA 2JA5C 1HI9A 1WQFA 3GSIA 3RZOK 1TWFC 4C2MK 1SFOA 2B63C 4Y52C 3GEEA 1I6HC 3GEHA 4NOIA 1O2FB 3TTGA 1AB4A 1WOOA 4LR2A 1TWAA 3GTMA 2R92C 1IL2A 1EK8A 5IYCK 5E68A 4C45A 3S0XA 2PMZL 4C3IK 2WAQD 1XXAA 3GTKA 5M3MK 1J98A 5C3EC 5C4JC 3PO2K 2Y0SL 4OIRA 3GTLA 3S1RK 1ZBSA 3A8JA 4C3HC 3EQLA 3G4CA 1O2BA 2NVTC 3FKIC 4Q5SA 4WJ3M 1R9TC 1XZPB 1K83A 1VH2A 5IYDC 4BLAA 4O2DA 3JSTA 5IP7C 2CFAA 4KMAA 4WJ4A 2WB1L 3HOWK 3SZYA 2NVQC 4GT9A 3FOEA 3S1QC 5EGEA 4C3JC 1USOA 4GTBA 3TFJA 4Q4ZA 2PA8L 4QJVB 2JA5A 3HOZK 2YU9C 3S2HK 1TWFA 1B4BA 4ZH4A 1HQMA 1DCOA 1UV7A 3S15C 5M5YK 1Y1WA 4G0VA 1JVIA 2E2JC 3AQPA 1J6WA 1WQGA 4GFQA 1Y1VC 2A68A 2JA7A 4ILDA 4A3CK 2P5MA 4BXXC 4M1XA 1EH1A 4A3JK 2JA8K 1TWGC 1DD5A 1DCHA 1TWCC 4LK1A 3FKIA 4KASA 3GTOA 2V6SA 3H0GA 4A3IC 3GTQC 1GE9A 1I3QK 3GTPK 4OIQA 3HOXC 2WAQL 1BS2A 5IP9C 3LPXA 4MEYA 2KWAA 1SFOC 1WSRA 4GTLA 1JOEA 3OEPA 4A3LK 3GTMC 2CFAB 5C44K 4AYBD 3G4AA 1YNJA 1O2AA 1BJTA 3GEIA 3QX3A 2O5JA 3AD7C 3S2DC 3PO3K 3AH5A 3GTGK 3GTLC 1PJ7A 2R93K 4BY1C 2GSUA 2E2IA 4KDDA 3S1MC 2VUMA 3FOFA 1Y1VA 3LAJA 3S1NK 1WCMK 1XPPA 1TWHA 5D4DA 4KARA 3WODA 4BKWA 5C4XK 4G0UA 3S16C 5IOTA 4DDQA 1TWCA 1O27A 2JA6A 4YFNA 3I4NC 3GTQA 1O29A 4PAAA 4BY7C 5IYBK 4KC6A 3H3VD 2R7ZK 3M4OK 1TWAK 4C3IC 2XCOA 3AD8C 1X31C 1PJ5A 2FQOA 5FJ8K 1WOSA 4A3MC 3GTKK 3A8IA 2RH6A 3S1RC 1O24A 1Y1WC 3K7AC 1VRQC 1YNNA 1ZQ1C 4KN7A 4LK0A 1EQRA 3GTJA 1PJ6A 4KAWX 2JA7C 3HOUK 4P9SA 4A3GC 2Y3PA 3CQZA 3HOYK 4GTEA 1INNA 1F9NA 4A3FK 3AD9C 3N0BA 3RZDK 3GTOC 3H0GC 2NVYA 4GTFA 4LOWA 3S17K 2NVXA 4AYBL 4P5BA 2JA5K 1IW7A 2W7VA 1TWFK 3N3YA 3A8KA 2XCQA 2B63K 1I6HK 1YCLA 3BP8C 2CW0A 2E2HC 4BBSC 4KN4A 4A3EC 2R92K 3TFHA 2A6EA 2GAGC 1BDFA 3I4MC 3HXAA 2PPBA 5C3EK 5C4JK 4XCHA 3S14C 4OIOA 5CHPA 4BBRC 1EFWA 3Q3QA 4KB4A 2E2IC 4C3HK 3L4KA 2VUMC 1I50C 3SZZA 2NVTK 3FKIK 2FQTA 3H3VL 1TWHC 4GTDA 4LJZA 4LLGA 1R9TK 4A3DC 3ADAC 5CJ9A 5IYDK 3OREA 4A93C 1XZQA 5IP7K 3HOVC 1IS1A 4QIWD 4KMHA 2NVQK 4X6AC 2JA6C 4Y7NC 3S1QK 4A3BK 4XLNA 4XSXA 2GSNA 4G0WA 1DCPA 1SMYA 2YU9K 2O5IA 4XSZA 1J6VA 3GTGC 3S15K 2E2HA 1VJEA 5FLMC 2E2JK 3HKZD 4FZBA 1Y1VK 3GTJC 4BXXK 3GDZA 4PABA 3CQZC 1TWGK 4A3KC 1I50A 2JH3A 4A3IK 2NVYC 2R7ZC 3GTQK 3GTPA 2NVXC 5M5WK 3HOXK 3FHZA 3RZOC 4C2MC 2V6TA 5IP9K 1SFOK 5IYCC 3GTMK 3BP3A 1XZQB 1I6VA 3PO2C 1IE0A 3GTGA 3S2DK 4QIWL 1USMA 3GTLK 1ZYRA 5L46A 4BY1K 4GZYA 3S1MK 3OPFA 1WCMA 1K83K 5IOQA 2A6HA 1WSVA 3CAGA 3HOWC 3S16K 1J6XA 1O28A 3M3YK 1O25A 5TMCA 5M5XK 3DXJA 1BGWA 3T02A 3I4NK 2R7ZA 1VGXA 2EBBA 4BY7K 3HKZL 5TJ3A 3HOZC 1IBAA 3S2HC 4KMUA 4OIPA 4WILA 4KM9A 1F7VA 1G51A 4YG2A 4A3MK 3L4JA 4Y52K 1WQHA 1Y1WK 3K7AK 4YFXA 1ZXOA 4OINA 3AQOA 4A3CC 1XXCA 2JA7K 1WIHA 1WORA 3VA7A 4XLPA 4A3JC 2JA8C 1JQWA 1IQ0A 2GAHC 5HL8A 5IOSA 1YX2A 4A3GK 2BE5A 4A3BC 2PHCB 3V4GA 4RMFA 1I3QC 1XXBA 3H0GK 3GTPC 3GTOK 3NUHA 1L0WA 4KATA 5JVOA 2ZUFA 2B63A 1RU0A 4C3JK 1C0AA 5JFEA 4A3LC 2XCRB 2E2HK 4BBSK 2R92A 4KB2A 5C44C 4A3EK 1EI6A
chains in the Genus database with same CATH topology
1USOA 2V6UA 1F93A 4WILA 1USMA 3JSTA 2V6TA 1DCPA 2V6SA 1DCOA 1DCHA 4LOWA 4C45A 1RU0A 2EBBA 3HXAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1USO A;  2V6U A;  1F93 A;  4WIL A;  1USM A;  3JST A;  2V6T A;  1DCP A;  2V6S A;  1DCO A;  1DCH A;  4LOW A;  4C45 A;  1RU0 A;  2EBB A;  3HXA A; 
#chains in the Genus database with same CATH topology
 3GIR A;  1F93 A;  4JK1 A;  4KMD A;  1VLO A;  4KM8 A;  4AH6 A;  3I4M K;  3IPJ A;  3PO3 C;  3TFI A;  3S14 K;  4BBR K;  2R93 C;  2E2I K;  1O26 A;  2GSO A;  2VUM K;  3S1N C;  1I50 K;  1WCM C;  1R9T A;  2PMZ D;  1TWH K;  4G7O A;  2P8T A;  4MQ9 A;  1F7U A;  4A3D K;  2RGR A;  5C4X C;  5TMF A;  2Y0S D;  2D6F C;  3MML B;  4A93 K;  4P5A A;  4BLB A;  3HOV K;  4G7Z A;  4LQY A;  1TWC K;  4X6A K;  2JA6 K;  4Y7N K;  3N0C A;  1I3Q A;  5IYB C;  1V5V A;  3M4O C;  4YFK A;  1TWA C;  2V6U A;  3T01 A;  2YU9 A;  4G7H A;  3GTK C;  1XZP A;  1KQ4 A;  2WB1 D;  4GTA A;  5IOR A;  2A69 A;  2ZUE A;  3ERE D;  1ZVU A;  5FLM K;  2PA8 D;  3HOU C;  1ISE A;  3GTJ K;  3T00 A;  1K83 C;  5M3F K;  4QJV A;  2R93 A;  1TWG A;  3HOY C;  2ZFZ A;  5EGH A;  3CQZ K;  4A3K K;  3M3Y C;  3LAP A;  4A3F C;  1WOP A;  3BUE A;  4FM9 A;  3RZD C;  1B4A A;  3S17 C;  4MEX A;  2NVY K;  4J3N A;  2NVX K;  4GTC A;  2JA5 C;  1HI9 A;  1WQF A;  3GSI A;  3RZO K;  1TWF C;  4C2M K;  1SFO A;  2B63 C;  4Y52 C;  3GEE A;  1I6H C;  3GEH A;  4NOI A;  1O2F B;  3TTG A;  1AB4 A;  1WOO A;  4LR2 A;  1TWA A;  3GTM A;  2R92 C;  1IL2 A;  1EK8 A;  5IYC K;  5E68 A;  4C45 A;  3S0X A;  2PMZ L;  4C3I K;  2WAQ D;  1XXA A;  3GTK A;  5M3M K;  1J98 A;  5C3E C;  5C4J C;  3PO2 K;  2Y0S L;  4OIR A;  3GTL A;  3S1R K;  1ZBS A;  3A8J A;  4C3H C;  3EQL A;  3G4C A;  1O2B A;  2NVT C;  3FKI C;  4Q5S A;  4WJ3 M;  1R9T C;  1XZP B;  1K83 A;  1VH2 A;  5IYD C;  4BLA A;  4O2D A;  3JST A;  5IP7 C;  2CFA A;  4KMA A;  4WJ4 A;  2WB1 L;  3HOW K;  3SZY A;  2NVQ C;  4GT9 A;  3FOE A;  3S1Q C;  5EGE A;  4C3J C;  1USO A;  4GTB A;  3TFJ A;  4Q4Z A;  2PA8 L;  4QJV B;  2JA5 A;  3HOZ K;  2YU9 C;  3S2H K;  1TWF A;  1B4B A;  4ZH4 A;  1HQM A;  1DCO A;  1UV7 A;  3S15 C;  5M5Y K;  1Y1W A;  4G0V A;  1JVI A;  2E2J C;  3AQP A;  1J6W A;  1WQG A;  4GFQ A;  1Y1V C;  2A68 A;  2JA7 A;  4ILD A;  4A3C K;  2P5M A;  4BXX C;  4M1X A;  1EH1 A;  4A3J K;  2JA8 K;  1TWG C;  1DD5 A;  1DCH A;  1TWC C;  4LK1 A;  3FKI A;  4KAS A;  3GTO A;  2V6S A;  3H0G A;  4A3I C;  3GTQ C;  1GE9 A;  1I3Q K;  3GTP K;  4OIQ A;  3HOX C;  2WAQ L;  1BS2 A;  5IP9 C;  3LPX A;  4MEY A;  2KWA A;  1SFO C;  1WSR A;  4GTL A;  1JOE A;  3OEP A;  4A3L K;  3GTM C;  2CFA B;  5C44 K;  4AYB D;  3G4A A;  1YNJ A;  1O2A A;  1BJT A;  3GEI A;  3QX3 A;  2O5J A;  3AD7 C;  3S2D C;  3PO3 K;  3AH5 A;  3GTG K;  3GTL C;  1PJ7 A;  2R93 K;  4BY1 C;  2GSU A;  2E2I A;  4KDD A;  3S1M C;  2VUM A;  3FOF A;  1Y1V A;  3LAJ A;  3S1N K;  1WCM K;  1XPP A;  1TWH A;  5D4D A;  4KAR A;  3WOD A;  4BKW A;  5C4X K;  4G0U A;  3S16 C;  5IOT A;  4DDQ A;  1TWC A;  1O27 A;  2JA6 A;  4YFN A;  3I4N C;  3GTQ A;  1O29 A;  4PAA A;  4BY7 C;  5IYB K;  4KC6 A;  3H3V D;  2R7Z K;  3M4O K;  1TWA K;  4C3I C;  2XCO A;  3AD8 C;  1X31 C;  1PJ5 A;  2FQO A;  5FJ8 K;  1WOS A;  4A3M C;  3GTK K;  3A8I A;  2RH6 A;  3S1R C;  1O24 A;  1Y1W C;  3K7A C;  1VRQ C;  1YNN A;  1ZQ1 C;  4KN7 A;  4LK0 A;  1EQR A;  3GTJ A;  1PJ6 A;  4KAW X;  2JA7 C;  3HOU K;  4P9S A;  4A3G C;  2Y3P A;  3CQZ A;  3HOY K;  4GTE A;  1INN A;  1F9N A;  4A3F K;  3AD9 C;  3N0B A;  3RZD K;  3GTO C;  3H0G C;  2NVY A;  4GTF A;  4LOW A;  3S17 K;  2NVX A;  4AYB L;  4P5B A;  2JA5 K;  1IW7 A;  2W7V A;  1TWF K;  3N3Y A;  3A8K A;  2XCQ A;  2B63 K;  1I6H K;  1YCL A;  3BP8 C;  2CW0 A;  2E2H C;  4BBS C;  4KN4 A;  4A3E C;  2R92 K;  3TFH A;  2A6E A;  2GAG C;  1BDF A;  3I4M C;  3HXA A;  2PPB A;  5C3E K;  5C4J K;  4XCH A;  3S14 C;  4OIO A;  5CHP A;  4BBR C;  1EFW A;  3Q3Q A;  4KB4 A;  2E2I C;  4C3H K;  3L4K A;  2VUM C;  1I50 C;  3SZZ A;  2NVT K;  3FKI K;  2FQT A;  3H3V L;  1TWH C;  4GTD A;  4LJZ A;  4LLG A;  1R9T K;  4A3D C;  3ADA C;  5CJ9 A;  5IYD K;  3ORE A;  4A93 C;  1XZQ A;  5IP7 K;  3HOV C;  1IS1 A;  4QIW D;  4KMH A;  2NVQ K;  4X6A C;  2JA6 C;  4Y7N C;  3S1Q K;  4A3B K;  4XLN A;  4XSX A;  2GSN A;  4G0W A;  1DCP A;  1SMY A;  2YU9 K;  2O5I A;  4XSZ A;  1J6V A;  3GTG C;  3S15 K;  2E2H A;  1VJE A;  5FLM C;  2E2J K;  3HKZ D;  4FZB A;  1Y1V K;  3GTJ C;  4BXX K;  3GDZ A;  4PAB A;  3CQZ C;  1TWG K;  4A3K C;  1I50 A;  2JH3 A;  4A3I K;  2NVY C;  2R7Z C;  3GTQ K;  3GTP A;  2NVX C;  5M5W K;  3HOX K;  3FHZ A;  3RZO C;  4C2M C;  2V6T A;  5IP9 K;  1SFO K;  5IYC C;  3GTM K;  3BP3 A;  1XZQ B;  1I6V A;  3PO2 C;  1IE0 A;  3GTG A;  3S2D K;  4QIW L;  1USM A;  3GTL K;  1ZYR A;  5L46 A;  4BY1 K;  4GZY A;  3S1M K;  3OPF A;  1WCM A;  1K83 K;  5IOQ A;  2A6H A;  1WSV A;  3CAG A;  3HOW C;  3S16 K;  1J6X A;  1O28 A;  3M3Y K;  1O25 A;  5TMC A;  5M5X K;  3DXJ A;  1BGW A;  3T02 A;  3I4N K;  2R7Z A;  1VGX A;  2EBB A;  4BY7 K;  3HKZ L;  5TJ3 A;  3HOZ C;  1IBA A;  3S2H C;  4KMU A;  4OIP A;  4WIL A;  4KM9 A;  1F7V A;  1G51 A;  4YG2 A;  4A3M K;  3L4J A;  4Y52 K;  1WQH A;  1Y1W K;  3K7A K;  4YFX A;  1ZXO A;  4OIN A;  3AQO A;  4A3C C;  1XXC A;  2JA7 K;  1WIH A;  1WOR A;  3VA7 A;  4XLP A;  4A3J C;  2JA8 C;  1JQW A;  1IQ0 A;  2GAH C;  5HL8 A;  5IOS A;  1YX2 A;  4A3G K;  2BE5 A;  4A3B C;  2PHC B;  3V4G A;  4RMF A;  1I3Q C;  1XXB A;  3H0G K;  3GTP C;  3GTO K;  3NUH A;  1L0W A;  4KAT A;  5JVO A;  2ZUF A;  2B63 A;  1RU0 A;  4C3J K;  1C0A A;  5JFE A;  4A3L C;  2XCR B;  2E2H K;  4BBS K;  2R92 A;  4KB2 A;  5C44 C;  4A3E K;  1EI6 A; 
#chains in the Genus database with same CATH homology
 1USO A;  2V6U A;  1F93 A;  4WIL A;  1USM A;  3JST A;  2V6T A;  1DCP A;  2V6S A;  1DCO A;  1DCH A;  4LOW A;  4C45 A;  1RU0 A;  2EBB A;  3HXA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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