The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
32
|
sequence length |
103
|
structure length |
103
|
Chain Sequence |
AGKAHRLSAEERDQLLPNLRAVGWNELEGRDAIFKQFHFKDFNRAFGFMTRVALQAEKLDHHPEWFNVYNKVHITLSTHECAGLSERDINLASFIEQVAVSMT
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Structural basis of dimerization, coactivator recognition and MODY3 mutations in HNF-1alpha.
pubmed doi rcsb |
| molecule tags |
Transcription
|
| source organism |
Rattus norvegicus
|
| molecule keywords |
DIMERIZATION COFACTOR OF HEPATOCYTE NUCLEAR FACTOR 1-ALPHA
|
| total genus |
32
|
| structure length |
103
|
| sequence length |
103
|
| chains with identical sequence |
B, C, D
|
| ec nomenclature |
ec
4.2.1.96: 4a-hydroxytetrahydrobiopterin dehydratase. |
| pdb deposition date | 2000-07-06 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF01329 | Pterin_4a | Pterin 4 alpha carbinolamine dehydratase |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | 2-Layer Sandwich | Gyrase A; domain 2 | Transcriptional coactivator/pterin dehydratase |
#chains in the Genus database with same CATH superfamily 1USO A; 4WIL A; 2V6S A; 3JST A; 1F93 A; 2V6U A; 1DCO A; 3HXA A; 2EBB A; 1DCH A; 2V6T A; 4LOW A; 1USM A; 1RU0 A; 1DCP A; 4C45 A; #chains in the Genus database with same CATH topology 3S1N C; 3K7A K; 3GTL C; 2PA8 D; 4A93 C; 4LR2 A; 4KDD A; 2E2I A; 3L4K A; 5C4X K; 5IP9 C; 3PO3 K; 3PO2 C; 4P9S A; 2E2I K; 2NVY A; 4YFK A; 3RZD C; 1ZYR A; 5C44 C; 3ADA C; 1ZQ1 C; 1Y1V A; 4A3I K; 3M3Y C; 2NVT C; 2A68 A; 1VGX A; 4XLP A; 2CW0 A; 4QIW D; 4A3J K; 3SZZ A; 4BLA A; 3FOE A; 4WIL A; 1INN A; 4C3I K; 3HXA A; 4C2M K; 3GTO C; 3GTL A; 5M3M K; 3S1N K; 2R92 C; 1I6H K; 1J6V A; 3A8I A; 3BUE A; 2JA5 K; 4A3D K; 5IP9 K; 5CJ9 A; 1TWG C; 4BY1 K; 5D4D A; 3BP8 C; 4GTA A; 3GTG A; 1WOR A; 1HI9 A; 2ZFZ A; 4A3L C; 3HOV K; 4LJZ A; 3S2D C; 1KQ4 A; 3GTO A; 3H0G C; 3GTO K; 4BY7 C; 2R92 K; 2XCO A; 2Y0S D; 5IYD C; 3S17 K; 3OEP A; 4QJV B; 1IE0 A; 1TWG A; 1XZQ B; 3T02 A; 5EGE A; 3L4J A; 1J6W A; 5C3E C; 3A8J A; 1V5V A; 3H0G A; 1XXB A; 4KMU A; 1ZBS A; 2JA7 C; 2EBB A; 4GTC A; 3H0G K; 4A3K K; 3HOU K; 4GFQ A; 3S15 C; 3S1Q C; 1O24 A; 3LAP A; 5IYD K; 4X6A C; 4Y7N C; 2VUM C; 2W7V A; 4G0U A; 1HQM A; 4A3F K; 1TWF K; 3I4N C; 1O27 A; 2CFA A; 1USO A; 2P8T A; 2JA7 A; 3S1M K; 4P5A A; 2BE5 A; 3A8K A; 4FZB A; 5JVO A; 1YNN A; 2JA7 K; 5M5X K; 3S1Q K; 2V6S A; 1WSV A; 4BBR K; 5C4X C; 2VUM A; 1BJT A; 4G7H A; 4OIN A; 4AYB L; 4G7O A; 4A3I C; 2D6F C; 4Q4Z A; 1R9T C; 3I4N K; 3GTK C; 4A3J C; 4WJ3 M; 4LK0 A; 4C3I C; 5IYB K; 1VH2 A; 3G4C A; 3HOW K; 4PAB A; 4C2M C; 3N0C A; 2RGR A; 3AD8 C; 3S0X A; 1I6H C; 2A69 A; 5HL8 A; 4A3D C; 2JA5 C; 3EQL A; 2R93 K; 4MQ9 A; 2E2H C; 4BY1 C; 3S16 K; 3M4O K; 4OIP A; 4OIR A; 1R9T A; 4KN4 A; 2R7Z K; 2O5J A; 5CHP A; 3CQZ K; 1R9T K; 5TMC A; 4LQY A; 3ORE A; 2O5I A; 3GTK K; 1F9N A; 3HOV C; 1XZP B; 3JST A; 4DDQ A; 1PJ6 A; 1Y1W K; 2JA5 A; 2V6U A; 3I4M C; 1IS1 A; 3S17 C; 1BGW A; 1J6X A; 2E2H A; 4XSZ A; 3IPJ A; 2E2H K; 3AQO A; 4GT9 A; 4QJV A; 3TFI A; 5L46 A; 3S14 K; 1F7U A; 2WB1 L; 4MEX A; 1O29 A; 3N3Y A; 5IYC C; 3GTM K; 2GSU A; 4XSX A; 5IP7 K; 1ZXO A; 2NVQ C; 4YFN A; 1C0A A; 4A3K C; 3HOX K; 2R92 A; 4C3J C; 4KB2 A; 3HOU C; 3LPX A; 1IW7 A; 4AYB D; 3I4M K; 1USM A; 3V4G A; 4XCH A; 5TJ3 A; 1WCM C; 1EK8 A; 1VJE A; 4A3F C; 3S2H K; 5M5W K; 4A3E C; 2NVX K; 1TWF C; 3LAJ A; 5IYC K; 4AH6 A; 3S1M C; 3GTQ K; 1IBA A; 1JOE A; 4YFX A; 4KMH A; 2NVQ K; 4G0W A; 4BKW A; 3DXJ A; 2A6E A; 4C3J K; 4BBR C; 1I50 K; 4KM9 A; 4Y52 K; 3BP3 A; 1EFW A; 2PA8 L; 3GTP C; 1WCM A; 1B4B A; 1F93 A; 5IOQ A; 4GTF A; 1WCM K; 1TWF A; 4J3N A; 4KM8 A; 1SMY A; 4A3E K; 1TWH K; 4YG2 A; 1TWC K; 4QIW L; 5IYB C; 3HOW C; 4JK1 A; 1AB4 A; 2JA8 C; 1K83 C; 1F7V A; 3FOF A; 3GTP A; 1DCP A; 4A3G C; 1I6V A; 2R93 C; 1XPP A; 2WB1 D; 3GTP K; 1SFO K; 3S16 C; 3M4O C; 1DCH A; 1EQR A; 1I3Q K; 3MML B; 1DD5 A; 4C3H C; 1B4A A; 3GEH A; 2R7Z C; 3AD9 C; 1WOO A; 3HOY K; 2GSO A; 3CQZ C; 1J98 A; 1BDF A; 4BLB A; 4KAT A; 4G0V A; 3T01 A; 1WQH A; 2ZUE A; 2XCQ A; 4MEY A; 1K83 A; 1Y1W C; 3AD7 C; 3RZO C; 2JA8 K; 1K83 K; 3FKI K; 4KN7 A; 2E2J K; 2R93 A; 4Q5S A; 2JH3 A; 1IQ0 A; 2KWA A; 2B63 K; 4GTD A; 4A3G K; 1GE9 A; 1XXA A; 2Y0S L; 3HKZ L; 1WQG A; 1Y1V C; 2R7Z A; 3ERE D; 1JQW A; 3S14 C; 3CQZ A; 4C3H K; 4LK1 A; 3GTK A; 1O26 A; 3GEI A; 3GTM C; 2GSN A; 4PAA A; 1PJ7 A; 5IOS A; 1L0W A; 4FM9 A; 5IP7 C; 4KAW X; 1Y1W A; 2YU9 K; 1VLO A; 1O2B A; 3HOX C; 4OIQ A; 4GTB A; 1TWA K; 3RZO K; 3GSI A; 4A3B K; 5JFE A; 2JA6 C; 4O2D A; 1IL2 A; 3TTG A; 2NVY K; 3HOZ K; 1Y1V K; 3WOD A; 3S2H C; 1XZQ A; 3GTG C; 3S1R K; 2NVX C; 3GTM A; 1O25 A; 2GAH C; 4BXX K; 1BS2 A; 2WAQ L; 1YX2 A; 5E68 A; 4BBS K; 3GTQ C; 1O28 A; 5FLM C; 3T00 A; 1G51 A; 3GTL K; 4A93 K; 3TFJ A; 2JA6 A; 1I50 C; 4Y52 C; 3PO2 K; 1WOS A; 5IOT A; 2JA6 K; 3Q3Q A; 3RZD K; 5C44 K; 1ZVU A; 1JVI A; 3SZY A; 3M3Y K; 1X31 C; 2NVT K; 2XCR B; 2NVX A; 4A3M C; 2RH6 A; 1XXC A; 3GTG K; 4OIO A; 1TWH C; 4KAR A; 2V6T A; 3GTQ A; 3AH5 A; 4GTL A; 3H3V L; 1TWC C; 4A3C C; 2FQT A; 5FLM K; 4LOW A; 4GZY A; 1YNJ A; 4KC6 A; 3OPF A; 1I50 A; 2PMZ L; 1UV7 A; 4WJ4 A; 2ZUF A; 3HKZ D; 4ZH4 A; 1YCL A; 1RU0 A; 1WOP A; 5FJ8 K; 4RMF A; 1TWG K; 1SFO C; 1WQF A; 2PHC B; 1O2F B; 1I3Q C; 4ILD A; 4C45 A; 1TWH A; 4A3M K; 3HOY C; 4NOI A; 4A3L K; 1EH1 A; 4KMA A; 3AQP A; 5EGH A; 1TWC A; 2Y3P A; 3S2D K; 3FHZ A; 5M3F K; 4M1X A; 3GIR A; 4A3C K; 4P5B A; 3GDZ A; 4BY7 K; 1WSR A; 2GAG C; 3FKI C; 3GEE A; 4XLN A; 3GTJ C; 2E2J C; 2P5M A; 2B63 C; 1SFO A; 1I3Q A; 1EI6 A; 4KB4 A; 4KMD A; 4KAS A; 2WAQ D; 5C3E K; 3NUH A; 1VRQ C; 2A6H A; 5C4J C; 1ISE A; 3CAG A; 3N0B A; 2YU9 C; 3G4A A; 1WIH A; 3K7A C; 5IOR A; 3FKI A; 3GTJ A; 3S15 K; 1XZP A; 1TWA C; 3QX3 A; 3PO3 C; 4LLG A; 2B63 A; 3GTJ K; 4A3B C; 4G7Z A; 2E2I C; 2PPB A; 4Y7N K; 5TMF A; 4X6A K; 2VUM K; 2NVY C; 1O2A A; 4GTE A; 5M5Y K; 3HOZ C; 2CFA B; 3H3V D; 3S1R C; 1DCO A; 2FQO A; 3TFH A; 4BXX C; 5C4J K; 3VA7 A; 2YU9 A; 2PMZ D; 4BBS C; 1PJ5 A; 1TWA A; #chains in the Genus database with same CATH homology 1USO A; 4WIL A; 2V6S A; 3JST A; 1F93 A; 2V6U A; 1DCO A; 3HXA A; 2EBB A; 1DCH A; 2V6T A; 4LOW A; 1USM A; 1RU0 A; 1DCP A; 4C45 A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
