1RU0A

Crystal structure of dcoh2, a paralog of dcoh, the dimerization cofactor of hnf-1
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
100
structure length
100
Chain Sequence
DAQWLTAEERDQLIPGLKAAGWSELSERDAIYKEFSFKNFNQAFGFMSRVALQAEKMNHHPEWFNVYNKVQITLTSHDCGGLTKRDVKLAQFIEKAAASL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Biochemical and structural basis for partially redundant enzymatic and transcriptional functions of DCoH and DCoH2
pubmed doi rcsb
molecule tags Lyase
source organism Mus musculus
molecule keywords DcoH-like protein DCoHm
total genus 37
structure length 100
sequence length 100
chains with identical sequence B
ec nomenclature ec 4.2.1.96: 4a-hydroxytetrahydrobiopterin dehydratase.
pdb deposition date 2003-12-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01329 Pterin_4a Pterin 4 alpha carbinolamine dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1360.20 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 Transcriptional coactivator/pterin dehydratase 1ru0A00
3JSTA 3HXAA 2V6TA 2V6SA 4WILA 1USMA 4C45A 4LOWA 1RU0A 1USOA 1DCPA 2V6UA 2EBBA 1DCOA 1DCHA 1F93A
chains in the Genus database with same CATH superfamily
1WCMA 2JA6C 3GTPA 1O2FB 1TWCA 5TMCA 3GTOA 5L46A 3RZOK 5TMFA 4LQYA 3GTKK 4BY1K 3S1RC 2YU9K 1TWGC 1TWHA 3H0GA 4YG2A 4KB2A 5M5YK 1PJ7A 1WOSA 3N0CA 4BKWA 4BBSC 2JA6K 4WJ4A 3I4MK 5M3MK 3GDZA 1I50A 2NVQC 1Y1VA 4A93C 3GEIA 3S17C 2NVXC 4J3NA 1J6XA 5IYDC 2R92K 3CQZA 3WODA 2XCOA 4BBSK 1J98A 2E2IA 1VJEA 1WQHA 3T01A 4AH6A 3FOFA 3S1QK 2NVTC 2NVQK 2ZUEA 4WJ3M 3TFJA 2JH3A 3S17K 5JVOA 2NVXK 3GTOC 3HOXK 4C3IC 2W7VA 2ZUFA 2WAQL 3T00A 1F93A 5C4JC 4WILA 3L4KA 3A8KA 3AH5A 3GTPK 1I50C 5M5WK 3GTOK 4KM9A 3FKIA 4OIRA 3S2HC 4KMDA 4C3IK 2XCQA 5C4XC 4OIQA 4G7OA 3GTMC 4KMUA 1I6HC 2GSOA 4A3JC 1IW7A 3TFHA 5M3FK 3GTJC 1I50K 3PO3C 4GFQA 3S2HK 4AYBL 2P8TA 3BP3A 1J6VA 2PHCB 1DCPA 5IOSA 3N0BA 4A3IK 5C4XK 2YU9A 3GTMK 4Q4ZA 1XZPA 3L4JA 4A3JK 3AD9C 1XZPB 4MEXA 2VUMA 2JA6A 2WB1L 3OEPA 3DXJA 1XPPA 3GTJK 1BS2A 3GEHA 1O27A 2R93C 3LAJA 4GTLA 5FLMK 3JSTA 1TWGA 3H3VD 4O2DA 4P9SA 4A3GK 3HOUC 4DDQA 4BLAA 1O28A 3HOVC 4Y7NC 1BJTA 1WORA 3A8IA 5JFEA 3S1MK 2XCRB 1WSRA 4KM8A 3GTGC 2R93K 1XXCA 2NVXA 2GSNA 5C3EC 3FKIK 3FOEA 4P5AA 1PJ6A 5E68A 3HOUK 1ZQ1C 4A3EK 4PAAA 1SMYA 3HOVK 4Y7NK 2VUMC 4KC6A 4X6AC 2A68A 1C0AA 4OIPA 2KWAA 2PMZL 4OIOA 3GTGK 4KB4A 1XXAA 3I4NC 1V5VA 3RZDC 1X31C 4G0VA 1B4AA 1YNNA 4BLBA 4XSXA 4KARA 1TWFC 4QIWD 2O5IA 2Y0SD 4A3LC 2VUMK 3SZZA 3PO2C 4NOIA 1O2AA 1I6VA 3S0XA 3RZDK 3S1RK 3BUEA 4XSZA 3GTMA 2R7ZC 4MEYA 4Q5SA 1DCOA 1TWGK 1WIHA 5IYCC 5CJ9A 1ZXOA 3S2DC 2B63C 4RMFA 3PO2K 2Y3PA 3HXAA 3GTJA 4A3MC 4A3FC 3GSIA 3S15C 4A93K 1SFOC 5IP9C 5IYCK 4KDDA 3S2DK 5IYDK 2B63K 1IS1A 5EGHA 4G7ZA 2NVYC 4A3MK 4A3FK 1IE0A 1Y1WA 2NVTK 1JQWA 1UV7A 3S15K 2R93A 1F7VA 5IP9K 4GTEA 1XXBA 4BY7C 4G0UA 4KAWX 5C4JK 4BXXC 2NVYK 1YNJA 2RGRA 3EQLA 3GTGA 5D4DA 4KATA 2CFAA 4GTBA 2CFAB 4XLNA 4BBRC 3S16C 1USMA 1I6HK 4C3JC 3S1NC 2PA8D 1HI9A 3ERED 1AB4A 5C44C 3BP8C 3M3YC 3GTQA 3HOWC 3PO3K 1Y1WC 1YCLA 3TTGA 3OREA 2V6UA 4KMAA 4BBRK 3AQPA 4GT9A 3S1NK 1TWFA 1EH1A 1O26A 5C44K 4Y52C 1WSVA 3M3YK 2E2JC 4LK0A 1EI6A 3HOWK 1Y1WK 3GTLC 2PPBA 3HKZD 1XZQA 2R7ZA 1XZQB 3AQOA 5CHPA 3H3VL 2A6EA 1BDFA 2B63A 4Y52K 2FQOA 2FQTA 2E2HC 1DCHA 5FJ8K 3GTQC 1SFOA 1IBAA 4C2MC 3S14C 1TWAC 2PMZD 1JVIA 4GTFA 5C3EK 1F9NA 3LPXA 3MMLB 1KQ4A 4ILDA 3GIRA 2NVYA 4X6AK 3GTQK 5M5XK 4GTCA 1K83C 4C2MK 5IORA 3I4NK 3S14K 1TWAK 4XCHA 3I4MC 3TFIA 2V6SA 1ISEA 1ZYRA 4FZBA 1TWFK 2P5MA 4QIWL 2JA7C 1O24A 1O29A 2Y0SL 4A3LK 5HL8A 3NUHA 1EK8A 4OINA 5IYBC 2R92C 1K83K 3CAGA 4A3KC 3LAPA 4GZYA 5TJ3A 2JA8C 1WOOA 3S1QC 4A3CC 1VLOA 2R7ZK 1USOA 4G0WA 2JA7K 3HOXC 4A3BC 5IYBK 2WAQD 3Q3QA 1O2BA 3HOYC 2JA5C 4A3KK 3M4OC 4YFKA 2JA8K 1GE9A 4GTDA 4A3CK 4KMHA 1SFOK 1R9TA 1O25A 1WCMC 1WOPA 1IQ0A 1VH2A 1B4BA 1PJ5A 3GTPC 1WQGA 1TWCC 1F7UA 1HQMA 4A3BK 4YFXA 1I3QA 3AD7C 2A69A 3K7AC 4M1XA 1RU0A 4LJZA 3HOYK 2JA5K 1TWHC 3H0GC 3IPJA 1L0WA 3GTLA 3M4OK 4A3DC 2GAHC 4PABA 1ZBSA 4GTAA 1WCMK 3N3YA 4XLPA 4BY7K 1TWCK 4C45A 4AYBD 1Y1VC 1J6WA 4LK1A 1G51A 4A3IC 3G4AA 4BXXK 3K7AK 1YX2A 4LLGA 1TWHK 1VGXA 3H0GK 5IP7C 2E2HA 2BE5A 4A3DK 3QX3A 3V4GA 1ZVUA 3CQZC 2WB1D 1TWAA 4FM9A 2E2IC 1R9TC 4KN4A 3S16K 2GSUA 1Y1VK 4C3JK 3A8JA 3GTKA 2PA8L 3AD8C 1INNA 3VA7A 2O5JA 5FLMC 2V6TA 4A3GC 1I3QC 2A6HA 1JOEA 1VRQC 4LOWA 5IP7K 4G7HA 2CW0A 1K83A 4QJVA 3CQZK 3GEEA 2E2IK 4JK1A 1EQRA 4QJVB 1R9TK 3S1MC 3HOZC 4P5BA 4C3HC 2ZFZA 2JA7A 1IL2A 3FKIC 2D6FC 4KASA 1I3QK 2E2JK 2RH6A 4A3EC 2R92A 3T02A 3GTLK 3G4CA 5EGEA 3HKZL 3HOZK 3SZYA 4KN7A 3ADAC 1DD5A 4C3HK 5IOQA 1WQFA 4MQ9A 2GAGC 3FHZA 3RZOC 3GTKC 4BY1C 2EBBA 1EFWA 2YU9C 4LR2A 4ZH4A 3OPFA 2JA5A 4YFNA 2E2HK 1BGWA 5IOTA
chains in the Genus database with same CATH topology
3JSTA 3HXAA 2V6TA 2V6SA 4WILA 1USMA 4C45A 4LOWA 1RU0A 1USOA 1DCPA 2V6UA 2EBBA 1DCOA 1DCHA 1F93A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3JST A;  3HXA A;  2V6T A;  2V6S A;  4WIL A;  1USM A;  4C45 A;  4LOW A;  1RU0 A;  1USO A;  1DCP A;  2V6U A;  2EBB A;  1DCO A;  1DCH A;  1F93 A; 
#chains in the Genus database with same CATH topology
 1WCM A;  2JA6 C;  3GTP A;  1O2F B;  1TWC A;  5TMC A;  3GTO A;  5L46 A;  3RZO K;  5TMF A;  4LQY A;  3GTK K;  4BY1 K;  3S1R C;  2YU9 K;  1TWG C;  1TWH A;  3H0G A;  4YG2 A;  4KB2 A;  5M5Y K;  1PJ7 A;  1WOS A;  3N0C A;  4BKW A;  4BBS C;  2JA6 K;  4WJ4 A;  3I4M K;  5M3M K;  3GDZ A;  1I50 A;  2NVQ C;  1Y1V A;  4A93 C;  3GEI A;  3S17 C;  2NVX C;  4J3N A;  1J6X A;  5IYD C;  2R92 K;  3CQZ A;  3WOD A;  2XCO A;  4BBS K;  1J98 A;  2E2I A;  1VJE A;  1WQH A;  3T01 A;  4AH6 A;  3FOF A;  3S1Q K;  2NVT C;  2NVQ K;  2ZUE A;  4WJ3 M;  3TFJ A;  2JH3 A;  3S17 K;  5JVO A;  2NVX K;  3GTO C;  3HOX K;  4C3I C;  2W7V A;  2ZUF A;  2WAQ L;  3T00 A;  1F93 A;  5C4J C;  4WIL A;  3L4K A;  3A8K A;  3AH5 A;  3GTP K;  1I50 C;  5M5W K;  3GTO K;  4KM9 A;  3FKI A;  4OIR A;  3S2H C;  4KMD A;  4C3I K;  2XCQ A;  5C4X C;  4OIQ A;  4G7O A;  3GTM C;  4KMU A;  1I6H C;  2GSO A;  4A3J C;  1IW7 A;  3TFH A;  5M3F K;  3GTJ C;  1I50 K;  3PO3 C;  4GFQ A;  3S2H K;  4AYB L;  2P8T A;  3BP3 A;  1J6V A;  2PHC B;  1DCP A;  5IOS A;  3N0B A;  4A3I K;  5C4X K;  2YU9 A;  3GTM K;  4Q4Z A;  1XZP A;  3L4J A;  4A3J K;  3AD9 C;  1XZP B;  4MEX A;  2VUM A;  2JA6 A;  2WB1 L;  3OEP A;  3DXJ A;  1XPP A;  3GTJ K;  1BS2 A;  3GEH A;  1O27 A;  2R93 C;  3LAJ A;  4GTL A;  5FLM K;  3JST A;  1TWG A;  3H3V D;  4O2D A;  4P9S A;  4A3G K;  3HOU C;  4DDQ A;  4BLA A;  1O28 A;  3HOV C;  4Y7N C;  1BJT A;  1WOR A;  3A8I A;  5JFE A;  3S1M K;  2XCR B;  1WSR A;  4KM8 A;  3GTG C;  2R93 K;  1XXC A;  2NVX A;  2GSN A;  5C3E C;  3FKI K;  3FOE A;  4P5A A;  1PJ6 A;  5E68 A;  3HOU K;  1ZQ1 C;  4A3E K;  4PAA A;  1SMY A;  3HOV K;  4Y7N K;  2VUM C;  4KC6 A;  4X6A C;  2A68 A;  1C0A A;  4OIP A;  2KWA A;  2PMZ L;  4OIO A;  3GTG K;  4KB4 A;  1XXA A;  3I4N C;  1V5V A;  3RZD C;  1X31 C;  4G0V A;  1B4A A;  1YNN A;  4BLB A;  4XSX A;  4KAR A;  1TWF C;  4QIW D;  2O5I A;  2Y0S D;  4A3L C;  2VUM K;  3SZZ A;  3PO2 C;  4NOI A;  1O2A A;  1I6V A;  3S0X A;  3RZD K;  3S1R K;  3BUE A;  4XSZ A;  3GTM A;  2R7Z C;  4MEY A;  4Q5S A;  1DCO A;  1TWG K;  1WIH A;  5IYC C;  5CJ9 A;  1ZXO A;  3S2D C;  2B63 C;  4RMF A;  3PO2 K;  2Y3P A;  3HXA A;  3GTJ A;  4A3M C;  4A3F C;  3GSI A;  3S15 C;  4A93 K;  1SFO C;  5IP9 C;  5IYC K;  4KDD A;  3S2D K;  5IYD K;  2B63 K;  1IS1 A;  5EGH A;  4G7Z A;  2NVY C;  4A3M K;  4A3F K;  1IE0 A;  1Y1W A;  2NVT K;  1JQW A;  1UV7 A;  3S15 K;  2R93 A;  1F7V A;  5IP9 K;  4GTE A;  1XXB A;  4BY7 C;  4G0U A;  4KAW X;  5C4J K;  4BXX C;  2NVY K;  1YNJ A;  2RGR A;  3EQL A;  3GTG A;  5D4D A;  4KAT A;  2CFA A;  4GTB A;  2CFA B;  4XLN A;  4BBR C;  3S16 C;  1USM A;  1I6H K;  4C3J C;  3S1N C;  2PA8 D;  1HI9 A;  3ERE D;  1AB4 A;  5C44 C;  3BP8 C;  3M3Y C;  3GTQ A;  3HOW C;  3PO3 K;  1Y1W C;  1YCL A;  3TTG A;  3ORE A;  2V6U A;  4KMA A;  4BBR K;  3AQP A;  4GT9 A;  3S1N K;  1TWF A;  1EH1 A;  1O26 A;  5C44 K;  4Y52 C;  1WSV A;  3M3Y K;  2E2J C;  4LK0 A;  1EI6 A;  3HOW K;  1Y1W K;  3GTL C;  2PPB A;  3HKZ D;  1XZQ A;  2R7Z A;  1XZQ B;  3AQO A;  5CHP A;  3H3V L;  2A6E A;  1BDF A;  2B63 A;  4Y52 K;  2FQO A;  2FQT A;  2E2H C;  1DCH A;  5FJ8 K;  3GTQ C;  1SFO A;  1IBA A;  4C2M C;  3S14 C;  1TWA C;  2PMZ D;  1JVI A;  4GTF A;  5C3E K;  1F9N A;  3LPX A;  3MML B;  1KQ4 A;  4ILD A;  3GIR A;  2NVY A;  4X6A K;  3GTQ K;  5M5X K;  4GTC A;  1K83 C;  4C2M K;  5IOR A;  3I4N K;  3S14 K;  1TWA K;  4XCH A;  3I4M C;  3TFI A;  2V6S A;  1ISE A;  1ZYR A;  4FZB A;  1TWF K;  2P5M A;  4QIW L;  2JA7 C;  1O24 A;  1O29 A;  2Y0S L;  4A3L K;  5HL8 A;  3NUH A;  1EK8 A;  4OIN A;  5IYB C;  2R92 C;  1K83 K;  3CAG A;  4A3K C;  3LAP A;  4GZY A;  5TJ3 A;  2JA8 C;  1WOO A;  3S1Q C;  4A3C C;  1VLO A;  2R7Z K;  1USO A;  4G0W A;  2JA7 K;  3HOX C;  4A3B C;  5IYB K;  2WAQ D;  3Q3Q A;  1O2B A;  3HOY C;  2JA5 C;  4A3K K;  3M4O C;  4YFK A;  2JA8 K;  1GE9 A;  4GTD A;  4A3C K;  4KMH A;  1SFO K;  1R9T A;  1O25 A;  1WCM C;  1WOP A;  1IQ0 A;  1VH2 A;  1B4B A;  1PJ5 A;  3GTP C;  1WQG A;  1TWC C;  1F7U A;  1HQM A;  4A3B K;  4YFX A;  1I3Q A;  3AD7 C;  2A69 A;  3K7A C;  4M1X A;  1RU0 A;  4LJZ A;  3HOY K;  2JA5 K;  1TWH C;  3H0G C;  3IPJ A;  1L0W A;  3GTL A;  3M4O K;  4A3D C;  2GAH C;  4PAB A;  1ZBS A;  4GTA A;  1WCM K;  3N3Y A;  4XLP A;  4BY7 K;  1TWC K;  4C45 A;  4AYB D;  1Y1V C;  1J6W A;  4LK1 A;  1G51 A;  4A3I C;  3G4A A;  4BXX K;  3K7A K;  1YX2 A;  4LLG A;  1TWH K;  1VGX A;  3H0G K;  5IP7 C;  2E2H A;  2BE5 A;  4A3D K;  3QX3 A;  3V4G A;  1ZVU A;  3CQZ C;  2WB1 D;  1TWA A;  4FM9 A;  2E2I C;  1R9T C;  4KN4 A;  3S16 K;  2GSU A;  1Y1V K;  4C3J K;  3A8J A;  3GTK A;  2PA8 L;  3AD8 C;  1INN A;  3VA7 A;  2O5J A;  5FLM C;  2V6T A;  4A3G C;  1I3Q C;  2A6H A;  1JOE A;  1VRQ C;  4LOW A;  5IP7 K;  4G7H A;  2CW0 A;  1K83 A;  4QJV A;  3CQZ K;  3GEE A;  2E2I K;  4JK1 A;  1EQR A;  4QJV B;  1R9T K;  3S1M C;  3HOZ C;  4P5B A;  4C3H C;  2ZFZ A;  2JA7 A;  1IL2 A;  3FKI C;  2D6F C;  4KAS A;  1I3Q K;  2E2J K;  2RH6 A;  4A3E C;  2R92 A;  3T02 A;  3GTL K;  3G4C A;  5EGE A;  3HKZ L;  3HOZ K;  3SZY A;  4KN7 A;  3ADA C;  1DD5 A;  4C3H K;  5IOQ A;  1WQF A;  4MQ9 A;  2GAG C;  3FHZ A;  3RZO C;  3GTK C;  4BY1 C;  2EBB A;  1EFW A;  2YU9 C;  4LR2 A;  4ZH4 A;  3OPF A;  2JA5 A;  4YFN A;  2E2H K;  1BGW A;  5IOT A; 
#chains in the Genus database with same CATH homology
 3JST A;  3HXA A;  2V6T A;  2V6S A;  4WIL A;  1USM A;  4C45 A;  4LOW A;  1RU0 A;  1USO A;  1DCP A;  2V6U A;  2EBB A;  1DCO A;  1DCH A;  1F93 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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