2V6TA

Crystal structure of a complex of pterin-4a-carbinolamine dehydratase from toxoplasma gondii with 7,8-dihydrobiopterin
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
99
structure length
99
Chain Sequence
ARLAANSARLLQLHKTVPQWHLTDGHLSIKRKFQFSDFNEAWGFMSRVALYADKVDHHPNWYNVYNTVDVELSTHDAAGLTEKDFALAKFMDDAAKNFE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lyase
source organism Toxoplasma gondii
publication title Crystal Structures of Toxoplasma Gondii Pterin-4A-Carbinolamine Dehydratase and Comparisons with Mammalian and Parasite Orthologues.
pubmed doi rcsb
molecule keywords PTERIN-4A-CARBINOLAMINE DEHYDRATASE
total genus 29
structure length 99
sequence length 99
chains with identical sequence B
ec nomenclature ec 4.2.1.96: 4a-hydroxytetrahydrobiopterin dehydratase.
pdb deposition date 2007-07-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01329 Pterin_4a Pterin 4 alpha carbinolamine dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1360.20 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 Transcriptional coactivator/pterin dehydratase 2v6tA00
3HXAA 2V6UA 1F93A 4LOWA 4C45A 1RU0A 3JSTA 2EBBA 1DCOA 1DCPA 1USOA 2V6TA 4WILA 1USMA 1DCHA 2V6SA
chains in the Genus database with same CATH superfamily
5FLMC 4LLGA 3PO3K 4PABA 5HL8A 1TWHA 1EK8A 4QJVB 3GDZA 1GE9A 3V4GA 1B4BA 3GTJC 3T01A 4GTEA 1I3QK 1ZVUA 2FQTA 2XCOA 4C3HK 5M5XK 4OINA 2V6SA 3S14K 4XLNA 1O2BA 4LQYA 5IOTA 1WOSA 1I50K 4GFQA 5IYBK 1TWGC 3QX3A 4A3KK 4BBRC 1XZQA 2P5MA 3H0GK 1O2FB 2R92C 2ZUFA 1XXAA 4A3MC 2JA7A 2RGRA 4A3EK 3ADAC 4LOWA 1TWHK 2EBBA 1L0WA 3FOEA 3SZZA 3GTJA 4A3LK 2JA8C 1IL2A 3PO2K 4OIPA 4KMHA 1SMYA 2XCQA 5IP9K 2NVYC 4YFNA 4LR2A 3GSIA 1VGXA 1TWGA 3G4CA 3S1RK 3HOZK 1O29A 1WIHA 1PJ6A 1DCHA 2JA7K 5IYCC 4X6AK 3WODA 1B4AA 2JA5C 3GTJK 4OIRA 1INNA 4KM9A 3S2DC 3OREA 2O5IA 1HQMA 4MEYA 2XCRB 4XLPA 1K83C 3TFHA 3M3YC 2WB1L 3BP3A 4KC6A 4C45A 3T02A 1F7VA 1I50C 3JSTA 2NVYA 1TWGK 5CJ9A 4BBRK 5IP7C 3MMLB 2R92K 3GTKC 4AYBL 3GTOK 2GSOA 3CQZC 3VA7A 2Y0SD 1WQHA 4QIWL 1WCMC 3RZDK 2E2IC 4GZYA 2JA5A 4A3LC 5JVOA 1F7UA 3N3YA 4M1XA 2A68A 3HOXC 3H3VL 3OEPA 2JA8K 3OPFA 3GTLC 1F9NA 1EI6A 2VUMC 1TWCC 1WOOA 1K83A 4FZBA 3SZYA 1TWFC 2NVYK 1I50A 3HOZC 2R93C 2JA6C 1J6XA 1O26A 4GTLA 2E2HC 5IOSA 3LPXA 3GTQC 3GTKA 5IYCK 4A3CC 3CQZA 4P9SA 4G7ZA 3Q3QA 4KMDA 5IYDC 2JA5K 1V5VA 4ILDA 1WCMA 2E2IA 1XZPA 4KMUA 3S2DK 4C3IC 1IW7A 2B63K 3A8JA 4XCHA 3GTLA 2V6TA 1K83K 3GEIA 3L4KA 3M3YK 2VUMA 1TWCA 3AD8C 4LK0A 1C0AA 1IBAA 1TWFA 3GTPC 3HKZL 3HOWC 4OIOA 5IP7K 3IPJA 2R93A 2JA6A 3GTOC 4XSXA 2FQOA 3GTKK 3S16C 2E2HA 2WAQL 3CQZK 1IQ0A 3GTQA 5M3MK 4WJ3M 1I6VA 1VLOA 3RZDC 1WCMK 2E2IK 2A6EA 4LJZA 5TJ3A 3S1MC 2CFAA 1Y1WC 3HOXK 4Y52C 1G51A 4BXXC 2NVXC 3GTLK 3GEEA 5TMCA 1AB4A 1O2AA 3NUHA 2PMZD 1JOEA 2GAHC 2VUMK 1TWCK 4QIWD 3TTGA 3BP8C 4A3BC 3TFJA 1TWFK 2A6HA 1PJ7A 4P5BA 5C4JK 2JH3A 2V6UA 2R93K 2JA6K 2D6FC 4O2DA 2E2HK 2YU9C 2R92A 3LAPA 1XZPB 1JQWA 3GTQK 3GTOA 1DD5A 5M5YK 4A3CK 1XXBA 1HI9A 3A8KA 5IYDK 4C3JC 1I6HC 4GT9A 4C2MC 5C44C 1Y1WA 2B63C 1J6VA 4BKWA 4XSZA 4C3IK 4YFKA 4DDQA 1XPPA 1IS1A 2PA8D 1XZQB 3S15C 2NVXA 2W7VA 2GSUA 2PPBA 3AD9C 3FKIC 3I4MC 3GTPK 1XXCA 3HOWK 1ZQ1C 5C4XC 4GTAA 3S17C 2A69A 4AH6A 2GAGC 4A3FC 2RH6A 4KN7A 4ZH4A 3BUEA 4BBSC 3S16K 2YU9A 3AD7C 4QJVA 4NOIA 3S1MK 4WILA 3GTMC 1Y1WK 4Y52K 4A3IC 2KWAA 2B63A 4BXXK 3LAJA 5TMFA 2NVXK 3T00A 1WORA 4P5AA 4WJ4A 5CHPA 4A3BK 4FM9A 5E68A 3I4NC 4A3GK 4KB2A 4RMFA 1USMA 3FKIA 5C4JC 4A3JC 1R9TK 3TFIA 2NVTC 1WQGA 2E2JC 1VRQC 3S1NC 2ZFZA 1WQFA 2YU9K 3FOFA 2R7ZC 4KDDA 4G7OA 1ZBSA 2Y3PA 4C3JK 1I6HK 4Y7NC 4LK1A 3GTGC 4C2MK 5C44K 3GTMA 4JK1A 5L46A 1BGWA 3S15K 4GTCA 1EFWA 1RU0A 3N0BA 4BLBA 2PHCB 3AH5A 2ZUEA 3FKIK 3I4MK 3GIRA 1EH1A 1VJEA 5C4XK 4OIQA 4KASA 1YCLA 4G7HA 4A3FK 3S17K 4G0WA 4KM8A 3HXAA 4BBSK 5EGEA 1TWAC 4GTFA 1IE0A 2R7ZA 3AQPA 5FJ8K 1ZYRA 3S0XA 2WB1D 2Y0SL 3K7AC 4YG2A 3RZOC 3FHZA 4PAAA 3GTMK 3GTGA 1WSVA 3S1QK 3HOUC 4A3IK 4BLAA 3HOYC 1DCPA 3M4OC 3L4JA 4A93C 4AYBD 1BDFA 2O5JA 3A8IA 1O24A 3EQLA 5JFEA 1Y1VC 4A3GC 3I4NK 3GTPA 1R9TC 4A3JK 2BE5A 2NVTK 2E2JK 3H3VD 4G0VA 3S1NK 5C3EC 2NVQC 1ZXOA 4MEXA 2GSNA 4J3NA 1BJTA 2R7ZK 1PJ5A 1USOA 1TWAA 1SFOC 4BY7C 4Y7NK 1WSRA 3GTGK 3G4AA 5IORA 3DXJA 3HOVC 4G0UA 4A3DK 1YX2A 3AQOA 3S2HK 1Y1VA 4BY1K 3PO3C 5FLMK 1R9TA 1YNNA 3ERED 4Q5SA 1I3QC 2CFAB 1F93A 4C3HC 1TWAK 3S14C 4KMAA 4KAWX 4MQ9A 1SFOA 3K7AK 3HKZD 4GTBA 1UV7A 3RZOK 1EQRA 4Q4ZA 1O27A 4YFXA 3S1QC 1O28A 3HOUK 5IYBC 1J6WA 4KN4A 1DCOA 4A3KC 3HOYK 3M4OK 4A93K 2WAQD 3H0GC 2CW0A 5IOQA 3CAGA 5EGHA 1Y1VK 1O25A 4A3EC 4A3MK 2PMZL 5M3FK 1TWHC 2P8TA 1WOPA 5M5WK 4KATA 1YNJA 5C3EK 2NVQK 1VH2A 1I3QA 4KB4A 3PO2C 1BS2A 1SFOK 5IP9C 4BY7K 1JVIA 1KQ4A 4GTDA 1J98A 3GEHA 1X31C 3N0CA 3S1RC 3HOVK 4KARA 5D4DA 1ISEA 4A3DC 3H0GA 2PA8L 3S2HC 2JA7C 4X6AC 4BY1C
chains in the Genus database with same CATH topology
3HXAA 2V6UA 1F93A 4LOWA 4C45A 1RU0A 3JSTA 2EBBA 1DCOA 1DCPA 1USOA 2V6TA 4WILA 1USMA 1DCHA 2V6SA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HXA A;  2V6U A;  1F93 A;  4LOW A;  4C45 A;  1RU0 A;  3JST A;  2EBB A;  1DCO A;  1DCP A;  1USO A;  2V6T A;  4WIL A;  1USM A;  1DCH A;  2V6S A; 
#chains in the Genus database with same CATH topology
 5FLM C;  4LLG A;  3PO3 K;  4PAB A;  5HL8 A;  1TWH A;  1EK8 A;  4QJV B;  3GDZ A;  1GE9 A;  3V4G A;  1B4B A;  3GTJ C;  3T01 A;  4GTE A;  1I3Q K;  1ZVU A;  2FQT A;  2XCO A;  4C3H K;  5M5X K;  4OIN A;  2V6S A;  3S14 K;  4XLN A;  1O2B A;  4LQY A;  5IOT A;  1WOS A;  1I50 K;  4GFQ A;  5IYB K;  1TWG C;  3QX3 A;  4A3K K;  4BBR C;  1XZQ A;  2P5M A;  3H0G K;  1O2F B;  2R92 C;  2ZUF A;  1XXA A;  4A3M C;  2JA7 A;  2RGR A;  4A3E K;  3ADA C;  4LOW A;  1TWH K;  2EBB A;  1L0W A;  3FOE A;  3SZZ A;  3GTJ A;  4A3L K;  2JA8 C;  1IL2 A;  3PO2 K;  4OIP A;  4KMH A;  1SMY A;  2XCQ A;  5IP9 K;  2NVY C;  4YFN A;  4LR2 A;  3GSI A;  1VGX A;  1TWG A;  3G4C A;  3S1R K;  3HOZ K;  1O29 A;  1WIH A;  1PJ6 A;  1DCH A;  2JA7 K;  5IYC C;  4X6A K;  3WOD A;  1B4A A;  2JA5 C;  3GTJ K;  4OIR A;  1INN A;  4KM9 A;  3S2D C;  3ORE A;  2O5I A;  1HQM A;  4MEY A;  2XCR B;  4XLP A;  1K83 C;  3TFH A;  3M3Y C;  2WB1 L;  3BP3 A;  4KC6 A;  4C45 A;  3T02 A;  1F7V A;  1I50 C;  3JST A;  2NVY A;  1TWG K;  5CJ9 A;  4BBR K;  5IP7 C;  3MML B;  2R92 K;  3GTK C;  4AYB L;  3GTO K;  2GSO A;  3CQZ C;  3VA7 A;  2Y0S D;  1WQH A;  4QIW L;  1WCM C;  3RZD K;  2E2I C;  4GZY A;  2JA5 A;  4A3L C;  5JVO A;  1F7U A;  3N3Y A;  4M1X A;  2A68 A;  3HOX C;  3H3V L;  3OEP A;  2JA8 K;  3OPF A;  3GTL C;  1F9N A;  1EI6 A;  2VUM C;  1TWC C;  1WOO A;  1K83 A;  4FZB A;  3SZY A;  1TWF C;  2NVY K;  1I50 A;  3HOZ C;  2R93 C;  2JA6 C;  1J6X A;  1O26 A;  4GTL A;  2E2H C;  5IOS A;  3LPX A;  3GTQ C;  3GTK A;  5IYC K;  4A3C C;  3CQZ A;  4P9S A;  4G7Z A;  3Q3Q A;  4KMD A;  5IYD C;  2JA5 K;  1V5V A;  4ILD A;  1WCM A;  2E2I A;  1XZP A;  4KMU A;  3S2D K;  4C3I C;  1IW7 A;  2B63 K;  3A8J A;  4XCH A;  3GTL A;  2V6T A;  1K83 K;  3GEI A;  3L4K A;  3M3Y K;  2VUM A;  1TWC A;  3AD8 C;  4LK0 A;  1C0A A;  1IBA A;  1TWF A;  3GTP C;  3HKZ L;  3HOW C;  4OIO A;  5IP7 K;  3IPJ A;  2R93 A;  2JA6 A;  3GTO C;  4XSX A;  2FQO A;  3GTK K;  3S16 C;  2E2H A;  2WAQ L;  3CQZ K;  1IQ0 A;  3GTQ A;  5M3M K;  4WJ3 M;  1I6V A;  1VLO A;  3RZD C;  1WCM K;  2E2I K;  2A6E A;  4LJZ A;  5TJ3 A;  3S1M C;  2CFA A;  1Y1W C;  3HOX K;  4Y52 C;  1G51 A;  4BXX C;  2NVX C;  3GTL K;  3GEE A;  5TMC A;  1AB4 A;  1O2A A;  3NUH A;  2PMZ D;  1JOE A;  2GAH C;  2VUM K;  1TWC K;  4QIW D;  3TTG A;  3BP8 C;  4A3B C;  3TFJ A;  1TWF K;  2A6H A;  1PJ7 A;  4P5B A;  5C4J K;  2JH3 A;  2V6U A;  2R93 K;  2JA6 K;  2D6F C;  4O2D A;  2E2H K;  2YU9 C;  2R92 A;  3LAP A;  1XZP B;  1JQW A;  3GTQ K;  3GTO A;  1DD5 A;  5M5Y K;  4A3C K;  1XXB A;  1HI9 A;  3A8K A;  5IYD K;  4C3J C;  1I6H C;  4GT9 A;  4C2M C;  5C44 C;  1Y1W A;  2B63 C;  1J6V A;  4BKW A;  4XSZ A;  4C3I K;  4YFK A;  4DDQ A;  1XPP A;  1IS1 A;  2PA8 D;  1XZQ B;  3S15 C;  2NVX A;  2W7V A;  2GSU A;  2PPB A;  3AD9 C;  3FKI C;  3I4M C;  3GTP K;  1XXC A;  3HOW K;  1ZQ1 C;  5C4X C;  4GTA A;  3S17 C;  2A69 A;  4AH6 A;  2GAG C;  4A3F C;  2RH6 A;  4KN7 A;  4ZH4 A;  3BUE A;  4BBS C;  3S16 K;  2YU9 A;  3AD7 C;  4QJV A;  4NOI A;  3S1M K;  4WIL A;  3GTM C;  1Y1W K;  4Y52 K;  4A3I C;  2KWA A;  2B63 A;  4BXX K;  3LAJ A;  5TMF A;  2NVX K;  3T00 A;  1WOR A;  4P5A A;  4WJ4 A;  5CHP A;  4A3B K;  4FM9 A;  5E68 A;  3I4N C;  4A3G K;  4KB2 A;  4RMF A;  1USM A;  3FKI A;  5C4J C;  4A3J C;  1R9T K;  3TFI A;  2NVT C;  1WQG A;  2E2J C;  1VRQ C;  3S1N C;  2ZFZ A;  1WQF A;  2YU9 K;  3FOF A;  2R7Z C;  4KDD A;  4G7O A;  1ZBS A;  2Y3P A;  4C3J K;  1I6H K;  4Y7N C;  4LK1 A;  3GTG C;  4C2M K;  5C44 K;  3GTM A;  4JK1 A;  5L46 A;  1BGW A;  3S15 K;  4GTC A;  1EFW A;  1RU0 A;  3N0B A;  4BLB A;  2PHC B;  3AH5 A;  2ZUE A;  3FKI K;  3I4M K;  3GIR A;  1EH1 A;  1VJE A;  5C4X K;  4OIQ A;  4KAS A;  1YCL A;  4G7H A;  4A3F K;  3S17 K;  4G0W A;  4KM8 A;  3HXA A;  4BBS K;  5EGE A;  1TWA C;  4GTF A;  1IE0 A;  2R7Z A;  3AQP A;  5FJ8 K;  1ZYR A;  3S0X A;  2WB1 D;  2Y0S L;  3K7A C;  4YG2 A;  3RZO C;  3FHZ A;  4PAA A;  3GTM K;  3GTG A;  1WSV A;  3S1Q K;  3HOU C;  4A3I K;  4BLA A;  3HOY C;  1DCP A;  3M4O C;  3L4J A;  4A93 C;  4AYB D;  1BDF A;  2O5J A;  3A8I A;  1O24 A;  3EQL A;  5JFE A;  1Y1V C;  4A3G C;  3I4N K;  3GTP A;  1R9T C;  4A3J K;  2BE5 A;  2NVT K;  2E2J K;  3H3V D;  4G0V A;  3S1N K;  5C3E C;  2NVQ C;  1ZXO A;  4MEX A;  2GSN A;  4J3N A;  1BJT A;  2R7Z K;  1PJ5 A;  1USO A;  1TWA A;  1SFO C;  4BY7 C;  4Y7N K;  1WSR A;  3GTG K;  3G4A A;  5IOR A;  3DXJ A;  3HOV C;  4G0U A;  4A3D K;  1YX2 A;  3AQO A;  3S2H K;  1Y1V A;  4BY1 K;  3PO3 C;  5FLM K;  1R9T A;  1YNN A;  3ERE D;  4Q5S A;  1I3Q C;  2CFA B;  1F93 A;  4C3H C;  1TWA K;  3S14 C;  4KMA A;  4KAW X;  4MQ9 A;  1SFO A;  3K7A K;  3HKZ D;  4GTB A;  1UV7 A;  3RZO K;  1EQR A;  4Q4Z A;  1O27 A;  4YFX A;  3S1Q C;  1O28 A;  3HOU K;  5IYB C;  1J6W A;  4KN4 A;  1DCO A;  4A3K C;  3HOY K;  3M4O K;  4A93 K;  2WAQ D;  3H0G C;  2CW0 A;  5IOQ A;  3CAG A;  5EGH A;  1Y1V K;  1O25 A;  4A3E C;  4A3M K;  2PMZ L;  5M3F K;  1TWH C;  2P8T A;  1WOP A;  5M5W K;  4KAT A;  1YNJ A;  5C3E K;  2NVQ K;  1VH2 A;  1I3Q A;  4KB4 A;  3PO2 C;  1BS2 A;  1SFO K;  5IP9 C;  4BY7 K;  1JVI A;  1KQ4 A;  4GTD A;  1J98 A;  3GEH A;  1X31 C;  3N0C A;  3S1R C;  3HOV K;  4KAR A;  5D4D A;  1ISE A;  4A3D C;  3H0G A;  2PA8 L;  3S2H C;  2JA7 C;  4X6A C;  4BY1 C; 
#chains in the Genus database with same CATH homology
 3HXA A;  2V6U A;  1F93 A;  4LOW A;  4C45 A;  1RU0 A;  3JST A;  2EBB A;  1DCO A;  1DCP A;  1USO A;  2V6T A;  4WIL A;  1USM A;  1DCH A;  2V6S A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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