2V6UA

High resolution crystal structure of pterin-4a-carbinolamine dehydratase from toxoplasma gondii
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
103
structure length
103
Chain Sequence
MAPLARLAANSARLLQLHKTVPQWHLTDGHLSIKRKFQFSDFNEAWGFMSRVALYADKVDHHPNWYNVYNTVDVELSTHDAAGLTEKDFALAKFMDDAAKNFE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures of Toxoplasma Gondii Pterin-4A-Carbinolamine Dehydratase and Comparisons with Mammalian and Parasite Orthologues.
pubmed doi rcsb
molecule tags Lyase
source organism Toxoplasma gondii
molecule keywords PTERIN-4A-CARBINOLAMINE DEHYDRATASE
total genus 32
structure length 103
sequence length 103
chains with identical sequence B
ec nomenclature ec 4.2.1.96: 4a-hydroxytetrahydrobiopterin dehydratase.
pdb deposition date 2007-07-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01329 Pterin_4a Pterin 4 alpha carbinolamine dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1360.20 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 Transcriptional coactivator/pterin dehydratase 2v6uA00
3HXAA 2V6SA 4LOWA 4C45A 2V6UA 1USMA 1F93A 2V6TA 3JSTA 1RU0A 1USOA 1DCOA 2EBBA 1DCHA 1DCPA 4WILA
chains in the Genus database with same CATH superfamily
4G0VA 4A3LC 4G7ZA 2E2HC 4GT9A 3ADAC 4A3JK 4OINA 1TWHK 2A6HA 1VLOA 4GZYA 2JA6K 3CAGA 2VUMA 4ZH4A 4A3EC 3GTQC 1J6WA 5C3EK 1O24A 5HL8A 4A93C 3S1MC 4C3IK 1KQ4A 3AQOA 5JVOA 4BXXC 3N0BA 5IYBK 3A8KA 1RU0A 4KATA 3TFIA 3HOVK 4A3JC 1DCHA 1TWHC 4A3BK 1PJ7A 2O5JA 2JA6C 3CQZA 3MMLB 2JH3A 5C3EC 4FM9A 1DD5A 3RZDK 1WQFA 1TWFK 3V4GA 4LQYA 4J3NA 4C3IC 1WCMA 3FKIK 5M5XK 1F93A 2GSUA 3LAPA 3OPFA 4RMFA 2V6SA 3GTLK 5IYBC 1IQ0A 4LLGA 3HOVC 4GTEA 5C4JK 4A3BC 3FKIA 2NVTK 1XZPA 5IP7K 1YNJA 3N3YA 2E2JK 1VJEA 3RZDC 4AYBD 4AH6A 5JFEA 1EFWA 3GTLA 1TWCK 1TWFC 1ZYRA 3AD7C 1I50K 4KB4A 4XSZA 4C3JK 3FKIC 2CFAA 3LAJA 3GTGA 4AYBL 1WOSA 5IYDK 1SMYA 3GEEA 3GTLC 2O5IA 3T02A 3HOWK 4JK1A 1PJ6A 1TWCA 1I50A 5C4JC 2FQOA 2NVTC 2A69A 5IP7C 3GTKK 2E2JC 4YFKA 4MEXA 3GTPK 4KM8A 4KASA 1TWCC 2E2IK 1I50C 4C3JC 3GTOA 3AD8C 1BGWA 2YU9K 3S1QC 5IYDC 5M3FK 3S17K 3H3VD 1XZPB 2WB1D 3GTKA 3IPJA 1XXAA 3HOWC 3GTPA 2R92K 4KC6A 4KM9A 2E2IA 3H0GK 2WB1L 3PO2K 2YU9A 5CJ9A 1VGXA 1ZBSA 4A3IK 2CFAB 3LPXA 1WQHA 4BKWA 1JVIA 3GTPC 2NVQK 3HOZK 2E2IC 2YU9C 4P5AA 3DXJA 4GTLA 3H0GA 1J98A 4YFNA 2VUMK 3S17C 3S1NK 4BBRK 2R92C 1XZQB 2WAQD 3H0GC 3PO2C 1HI9A 4GTCA 2NVYC 4A3IC 4A3GK 4C3HK 2WAQL 3GSIA 1O27A 3TTGA 2NVQC 3JSTA 3HOZC 4LJZA 4QJVA 3T00A 2XCOA 1EQRA 3TFJA 3CQZK 5FLMK 2VUMC 4GTFA 3S1NC 4BBRC 3VA7A 1WCMK 4KAWX 1B4BA 4Y7NK 4A3GC 4C3HC 3S2HK 1O29A 3S14K 1EK8A 3GTJK 1J6XA 3ERED 4BBSK 1DCOA 3K7AK 2GSNA 4OIRA 5D4DA 1K83K 3CQZC 5FLMC 4OIOA 1JQWA 5IYCK 3AQPA 1HQMA 1O2FB 3FHZA 2PHCB 3GTJA 2D6FC 1ZQ1C 1WCMC 3S1RK 1B4AA 4OIPA 1EI6A 3GTGK 1IE0A 2P5MA 3AD9C 4Y7NC 4LK1A 4XSXA 3GIRA 1K83A 4QJVB 4A3MK 2PMZD 4Q5SA 3S14C 3GTJC 1L0WA 3AH5A 3M3YK 5EGHA 1K83C 4KB2A 4MEYA 1INNA 1VH2A 5IYCC 3TFHA 3OREA 4C45A 3BP8C 3S1RC 3GTOK 3GTGC 2R7ZK 3FOFA 4A3MC 1O25A 3S2DK 1TWAK 1USMA 1F7VA 3I4MK 3M4OK 3M3YC 2Y3PA 1X31C 3PO3K 2R7ZA 3GEHA 4QIWD 1IW7A 4Y52K 2NVXA 4GTBA 4BLBA 1IS1A 5EGEA 1Y1WK 1TWAA 1YNNA 1Y1VK 3GTOC 3H3VL 2ZUFA 2R7ZC 2W7VA 1WSVA 4GTAA 4MQ9A 2EBBA 3SZYA 3GTKC 1TWAC 3I4MC 3M4OC 4G7OA 1Y1WA 2P8TA 3PO3C 2CW0A 1Y1VA 2JA5K 1BS2A 4FZBA 4Y52C 4X6AK 2GSOA 1BJTA 3HOXK 5IOQA 4BY7K 4KMUA 1Y1WC 1IL2A 1Y1VC 4C2MK 4WILA 2A68A 2JA5A 5TMCA 1I6HK 4PABA 3FOEA 2GAGC 3SZZA 1WORA 4BY1K 5CHPA 2JA5C 3HOYK 3G4CA 2PA8D 4KMAA 4X6AC 5C4XK 3GTQA 3HOXC 1F9NA 3A8IA 2KWAA 2B63K 4PAAA 1O26A 4BY7C 4KMHA 2PA8L 3GDZA 4C2MC 1ZVUA 4KN4A 1DCPA 5IP9K 3L4JA 1I6HC 3G4AA 2RH6A 4G7HA 4WJ3M 4DDQA 3A8JA 3BUEA 4P5BA 1YX2A 2B63A 1G51A 4G0UA 4BY1C 1O2AA 3GTMK 3HXAA 2R93K 1TWHA 1TWGK 3HOYC 1O2BA 2JA6A 1ZXOA 4YG2A 1WOPA 5C4XC 1WOOA 1BDFA 1XXCA 2B63C 4GFQA 2V6TA 3NUHA 3WODA 5IP9C 3GTMA 2R93A 2V6UA 1TWGA 4A3KK 1WQGA 4KARA 3N0CA 5TMFA 5M5YK 4OIQA 3S2HC 2FQTA 1I3QK 3I4NK 3GTMC 4BBSC 2R93C 3K7AC 1TWGC 2PMZL 5IORA 4LR2A 1EH1A 1V5VA 5M3MK 3S16K 3S0XA 4WJ4A 1WIHA 3GEIA 1TWFA 4XCHA 1I3QA 2BE5A 2ZUEA 1J6VA 1C0AA 4A3DK 5IOSA 4A3KC 1XXBA 4KMDA 3RZOK 2NVXK 2Y0SD 1YCLA 1I3QC 3I4NC 2ZFZA 1SFOK 2RGRA 2Y0SL 5M5WK 3S1QK 1PJ5A 4O2DA 1JOEA 1F7UA 4P9SA 4XLPA 2GAHC 3S16C 4NOIA 1UV7A 4G0WA 4QIWL 4KN7A 5E68A 1SFOA 4BLAA 4XLNA 4A3DC 1R9TK 4KDDA 3L4KA 3RZOC 1XZQA 2JA8K 2NVXC 3EQLA 3S2DC 4YFXA 1SFOC 2JA7K 1VRQC 5C44K 3HKZD 1I6VA 3HOUK 5L46A 3S15K 4A3FK 1R9TA 4A3CK 3HKZL 4LK0A 1ISEA 2XCQA 2XCRB 4A3LK 1AB4A 2E2HK 1GE9A 2JA7A 4GTDA 5IOTA 1WSRA 1O28A 2NVYK 3Q3QA 5FJ8K 1R9TC 2PPBA 4ILDA 3T01A 4A3EK 2JA8C 3GTQK 4LOWA 2A6EA 2R92A 2JA7C 4A93K 3S1MK 3QX3A 5TJ3A 5C44C 2E2HA 3OEPA 1XPPA 4M1XA 2NVYA 3HOUC 1USOA 3S15C 4A3FC 3BP3A 4A3CC 4BXXK 1IBAA 4Q4ZA
chains in the Genus database with same CATH topology
3HXAA 2V6SA 4LOWA 4C45A 2V6UA 1USMA 1F93A 2V6TA 3JSTA 1RU0A 1USOA 1DCOA 2EBBA 1DCHA 1DCPA 4WILA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HXA A;  2V6S A;  4LOW A;  4C45 A;  2V6U A;  1USM A;  1F93 A;  2V6T A;  3JST A;  1RU0 A;  1USO A;  1DCO A;  2EBB A;  1DCH A;  1DCP A;  4WIL A; 
#chains in the Genus database with same CATH topology
 4G0V A;  4A3L C;  4G7Z A;  2E2H C;  4GT9 A;  3ADA C;  4A3J K;  4OIN A;  1TWH K;  2A6H A;  1VLO A;  4GZY A;  2JA6 K;  3CAG A;  2VUM A;  4ZH4 A;  4A3E C;  3GTQ C;  1J6W A;  5C3E K;  1O24 A;  5HL8 A;  4A93 C;  3S1M C;  4C3I K;  1KQ4 A;  3AQO A;  5JVO A;  4BXX C;  3N0B A;  5IYB K;  3A8K A;  1RU0 A;  4KAT A;  3TFI A;  3HOV K;  4A3J C;  1DCH A;  1TWH C;  4A3B K;  1PJ7 A;  2O5J A;  2JA6 C;  3CQZ A;  3MML B;  2JH3 A;  5C3E C;  4FM9 A;  1DD5 A;  3RZD K;  1WQF A;  1TWF K;  3V4G A;  4LQY A;  4J3N A;  4C3I C;  1WCM A;  3FKI K;  5M5X K;  1F93 A;  2GSU A;  3LAP A;  3OPF A;  4RMF A;  2V6S A;  3GTL K;  5IYB C;  1IQ0 A;  4LLG A;  3HOV C;  4GTE A;  5C4J K;  4A3B C;  3FKI A;  2NVT K;  1XZP A;  5IP7 K;  1YNJ A;  3N3Y A;  2E2J K;  1VJE A;  3RZD C;  4AYB D;  4AH6 A;  5JFE A;  1EFW A;  3GTL A;  1TWC K;  1TWF C;  1ZYR A;  3AD7 C;  1I50 K;  4KB4 A;  4XSZ A;  4C3J K;  3FKI C;  2CFA A;  3LAJ A;  3GTG A;  4AYB L;  1WOS A;  5IYD K;  1SMY A;  3GEE A;  3GTL C;  2O5I A;  3T02 A;  3HOW K;  4JK1 A;  1PJ6 A;  1TWC A;  1I50 A;  5C4J C;  2FQO A;  2NVT C;  2A69 A;  5IP7 C;  3GTK K;  2E2J C;  4YFK A;  4MEX A;  3GTP K;  4KM8 A;  4KAS A;  1TWC C;  2E2I K;  1I50 C;  4C3J C;  3GTO A;  3AD8 C;  1BGW A;  2YU9 K;  3S1Q C;  5IYD C;  5M3F K;  3S17 K;  3H3V D;  1XZP B;  2WB1 D;  3GTK A;  3IPJ A;  1XXA A;  3HOW C;  3GTP A;  2R92 K;  4KC6 A;  4KM9 A;  2E2I A;  3H0G K;  2WB1 L;  3PO2 K;  2YU9 A;  5CJ9 A;  1VGX A;  1ZBS A;  4A3I K;  2CFA B;  3LPX A;  1WQH A;  4BKW A;  1JVI A;  3GTP C;  2NVQ K;  3HOZ K;  2E2I C;  2YU9 C;  4P5A A;  3DXJ A;  4GTL A;  3H0G A;  1J98 A;  4YFN A;  2VUM K;  3S17 C;  3S1N K;  4BBR K;  2R92 C;  1XZQ B;  2WAQ D;  3H0G C;  3PO2 C;  1HI9 A;  4GTC A;  2NVY C;  4A3I C;  4A3G K;  4C3H K;  2WAQ L;  3GSI A;  1O27 A;  3TTG A;  2NVQ C;  3JST A;  3HOZ C;  4LJZ A;  4QJV A;  3T00 A;  2XCO A;  1EQR A;  3TFJ A;  3CQZ K;  5FLM K;  2VUM C;  4GTF A;  3S1N C;  4BBR C;  3VA7 A;  1WCM K;  4KAW X;  1B4B A;  4Y7N K;  4A3G C;  4C3H C;  3S2H K;  1O29 A;  3S14 K;  1EK8 A;  3GTJ K;  1J6X A;  3ERE D;  4BBS K;  1DCO A;  3K7A K;  2GSN A;  4OIR A;  5D4D A;  1K83 K;  3CQZ C;  5FLM C;  4OIO A;  1JQW A;  5IYC K;  3AQP A;  1HQM A;  1O2F B;  3FHZ A;  2PHC B;  3GTJ A;  2D6F C;  1ZQ1 C;  1WCM C;  3S1R K;  1B4A A;  4OIP A;  1EI6 A;  3GTG K;  1IE0 A;  2P5M A;  3AD9 C;  4Y7N C;  4LK1 A;  4XSX A;  3GIR A;  1K83 A;  4QJV B;  4A3M K;  2PMZ D;  4Q5S A;  3S14 C;  3GTJ C;  1L0W A;  3AH5 A;  3M3Y K;  5EGH A;  1K83 C;  4KB2 A;  4MEY A;  1INN A;  1VH2 A;  5IYC C;  3TFH A;  3ORE A;  4C45 A;  3BP8 C;  3S1R C;  3GTO K;  3GTG C;  2R7Z K;  3FOF A;  4A3M C;  1O25 A;  3S2D K;  1TWA K;  1USM A;  1F7V A;  3I4M K;  3M4O K;  3M3Y C;  2Y3P A;  1X31 C;  3PO3 K;  2R7Z A;  3GEH A;  4QIW D;  1IW7 A;  4Y52 K;  2NVX A;  4GTB A;  4BLB A;  1IS1 A;  5EGE A;  1Y1W K;  1TWA A;  1YNN A;  1Y1V K;  3GTO C;  3H3V L;  2ZUF A;  2R7Z C;  2W7V A;  1WSV A;  4GTA A;  4MQ9 A;  2EBB A;  3SZY A;  3GTK C;  1TWA C;  3I4M C;  3M4O C;  4G7O A;  1Y1W A;  2P8T A;  3PO3 C;  2CW0 A;  1Y1V A;  2JA5 K;  1BS2 A;  4FZB A;  4Y52 C;  4X6A K;  2GSO A;  1BJT A;  3HOX K;  5IOQ A;  4BY7 K;  4KMU A;  1Y1W C;  1IL2 A;  1Y1V C;  4C2M K;  4WIL A;  2A68 A;  2JA5 A;  5TMC A;  1I6H K;  4PAB A;  3FOE A;  2GAG C;  3SZZ A;  1WOR A;  4BY1 K;  5CHP A;  2JA5 C;  3HOY K;  3G4C A;  2PA8 D;  4KMA A;  4X6A C;  5C4X K;  3GTQ A;  3HOX C;  1F9N A;  3A8I A;  2KWA A;  2B63 K;  4PAA A;  1O26 A;  4BY7 C;  4KMH A;  2PA8 L;  3GDZ A;  4C2M C;  1ZVU A;  4KN4 A;  1DCP A;  5IP9 K;  3L4J A;  1I6H C;  3G4A A;  2RH6 A;  4G7H A;  4WJ3 M;  4DDQ A;  3A8J A;  3BUE A;  4P5B A;  1YX2 A;  2B63 A;  1G51 A;  4G0U A;  4BY1 C;  1O2A A;  3GTM K;  3HXA A;  2R93 K;  1TWH A;  1TWG K;  3HOY C;  1O2B A;  2JA6 A;  1ZXO A;  4YG2 A;  1WOP A;  5C4X C;  1WOO A;  1BDF A;  1XXC A;  2B63 C;  4GFQ A;  2V6T A;  3NUH A;  3WOD A;  5IP9 C;  3GTM A;  2R93 A;  2V6U A;  1TWG A;  4A3K K;  1WQG A;  4KAR A;  3N0C A;  5TMF A;  5M5Y K;  4OIQ A;  3S2H C;  2FQT A;  1I3Q K;  3I4N K;  3GTM C;  4BBS C;  2R93 C;  3K7A C;  1TWG C;  2PMZ L;  5IOR A;  4LR2 A;  1EH1 A;  1V5V A;  5M3M K;  3S16 K;  3S0X A;  4WJ4 A;  1WIH A;  3GEI A;  1TWF A;  4XCH A;  1I3Q A;  2BE5 A;  2ZUE A;  1J6V A;  1C0A A;  4A3D K;  5IOS A;  4A3K C;  1XXB A;  4KMD A;  3RZO K;  2NVX K;  2Y0S D;  1YCL A;  1I3Q C;  3I4N C;  2ZFZ A;  1SFO K;  2RGR A;  2Y0S L;  5M5W K;  3S1Q K;  1PJ5 A;  4O2D A;  1JOE A;  1F7U A;  4P9S A;  4XLP A;  2GAH C;  3S16 C;  4NOI A;  1UV7 A;  4G0W A;  4QIW L;  4KN7 A;  5E68 A;  1SFO A;  4BLA A;  4XLN A;  4A3D C;  1R9T K;  4KDD A;  3L4K A;  3RZO C;  1XZQ A;  2JA8 K;  2NVX C;  3EQL A;  3S2D C;  4YFX A;  1SFO C;  2JA7 K;  1VRQ C;  5C44 K;  3HKZ D;  1I6V A;  3HOU K;  5L46 A;  3S15 K;  4A3F K;  1R9T A;  4A3C K;  3HKZ L;  4LK0 A;  1ISE A;  2XCQ A;  2XCR B;  4A3L K;  1AB4 A;  2E2H K;  1GE9 A;  2JA7 A;  4GTD A;  5IOT A;  1WSR A;  1O28 A;  2NVY K;  3Q3Q A;  5FJ8 K;  1R9T C;  2PPB A;  4ILD A;  3T01 A;  4A3E K;  2JA8 C;  3GTQ K;  4LOW A;  2A6E A;  2R92 A;  2JA7 C;  4A93 K;  3S1M K;  3QX3 A;  5TJ3 A;  5C44 C;  2E2H A;  3OEP A;  1XPP A;  4M1X A;  2NVY A;  3HOU C;  1USO A;  3S15 C;  4A3F C;  3BP3 A;  4A3C C;  4BXX K;  1IBA A;  4Q4Z A; 
#chains in the Genus database with same CATH homology
 3HXA A;  2V6S A;  4LOW A;  4C45 A;  2V6U A;  1USM A;  1F93 A;  2V6T A;  3JST A;  1RU0 A;  1USO A;  1DCO A;  2EBB A;  1DCH A;  1DCP A;  4WIL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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