2V6SA

Medium resolution crystal structure of pterin-4a-carbinolamine dehydratase from toxoplasma gondii
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
102
structure length
102
Chain Sequence
MAPLARLAANSARLLQLHKTVPQWHLTDGHLSIKRKFQFSDFNEAWGFMSRVALYADKVDHHPNWYNVYNTVDVELSTHDAAGLTEKDFALAKFMDDAAKNF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures of Toxoplasma Gondii Pterin-4A-Carbinolamine Dehydratase and Comparisons with Mammalian and Parasite Orthologues.
pubmed doi rcsb
molecule tags Lyase
source organism Toxoplasma gondii
molecule keywords PTERIN-4A-CARBINOLAMINE DEHYDRATASE
total genus 29
structure length 102
sequence length 102
chains with identical sequence B
ec nomenclature ec 4.2.1.96: 4a-hydroxytetrahydrobiopterin dehydratase.
pdb deposition date 2007-07-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01329 Pterin_4a Pterin 4 alpha carbinolamine dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1360.20 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 Transcriptional coactivator/pterin dehydratase 2v6sA00
1DCOA 1USMA 1RU0A 3JSTA 1DCPA 2V6TA 2V6SA 3HXAA 4LOWA 4C45A 2EBBA 1USOA 2V6UA 1F93A 1DCHA 4WILA
chains in the Genus database with same CATH superfamily
4Y52K 4BY7K 4BLBA 1JVIA 3RZDC 2NVYA 4A3JK 3S14K 2NVXA 3T02A 2E2JC 1DCOA 1WIHA 4KM9A 2XCRB 1I3QK 4JK1A 2B63A 1O28A 4C2MC 4A3KK 3HOYC 3BUEA 5CHPA 4AH6A 1F9NA 3GTPC 3I4MC 4KASA 3H3VD 2R93A 4C3JK 1VLOA 3K7AK 3OPFA 3GTQA 1DD5A 4LQYA 3GIRA 3TFHA 4P5BA 4OIRA 4A3EK 3HOWK 4GTCA 3H3VL 5C4XK 1ISEA 1I6VA 4A3CK 4C3HC 1XZQA 2WAQL 5D4DA 2E2IA 4ILDA 1WOSA 2WB1D 4MQ9A 3S1QC 1I50A 4MEXA 5CJ9A 2GAHC 2ZUFA 3GTKK 4QJVA 3I4NK 1YX2A 1VGXA 3GEIA 2D6FC 1XZPA 3GTLC 2R7ZC 4A3DC 3A8IA 2VUMK 4OIPA 1KQ4A 1TWAA 3I4MK 3QX3A 3GTGK 3HOUK 3RZOC 2RH6A 1WOPA 2Y0SD 2Y3PA 3HOZK 2JA6A 4A3IC 2FQTA 4GTAA 2A6EA 4LK0A 5HL8A 4KMAA 4GT9A 1F93A 5IORA 1XZQB 2E2HA 2Y0SL 1Y1VC 3AD8C 4PAAA 4GZYA 3TTGA 3S2HC 4G7HA 5IYCK 4A3BC 3MMLB 3GTLK 1Y1WK 2JA5A 2W7VA 1USMA 3CQZC 3T00A 4KC6A 1TWHK 3GTMK 1V5VA 5M3MK 3S1MC 4GTLA 2B63C 4BBSK 3S2DC 1F7UA 4KB4A 3S15C 1IE0A 1G51A 3H0GA 5C3EK 3HKZD 4FM9A 1PJ5A 4KM8A 4A3IK 3GTQC 3GEHA 1J98A 4KARA 4LLGA 4Q4ZA 1JOEA 1C0AA 1SFOK 5E68A 1EI6A 1TWCA 1XXBA 5TJ3A 3HKZL 1Y1VK 5C44C 2E2IC 2XCOA 3LAJA 3N0CA 3S17C 1I50C 2JA8C 1TWGK 2BE5A 4G7OA 3CQZK 4YFNA 4YFKA 4PABA 2CW0A 4A3MK 2O5IA 4KN7A 3S15K 1TWAC 3M3YC 1WSRA 4G0UA 2XCQA 1K83K 3AD9C 1J6WA 2JA6C 4G0VA 4OIQA 4KATA 4GTBA 3S1NC 3N3YA 1WCMK 3IPJA 5IYBK 3PO2C 3A8JA 2R92A 2EBBA 1R9TA 1O24A 3OREA 4OINA 5IP9C 3GTOA 5TMFA 4A3GK 2E2HC 3CAGA 5IP7C 3FKIA 3S1RK 5IYDC 3FOEA 3PO3K 2JA7A 5EGHA 2YU9A 1I6HC 2JA5C 5EGEA 1IS1A 4GTFA 4C3IC 4XCHA 3L4JA 1TWFK 3FOFA 4A3LC 3VA7A 3HOXC 3RZDK 3NUHA 3H0GC 3EQLA 5JVOA 2E2JK 3G4AA 4XLNA 1I3QA 2NVTC 4C2MK 3HOYK 1B4AA 1WCMA 4A3FC 4KMUA 3N0BA 4YFXA 2WB1L 3GTPK 3SZYA 5IP9K 1TWCC 4X6AC 2CFAA 1O27A 1EK8A 2A68A 3GTJC 1I6HK 1BDFA 2ZFZA 1SMYA 4C3HK 1X31C 3S1QK 1J6VA 1ZBSA 3GTKA 1WQGA 2NVYC 2NVXC 2R7ZK 4A3DK 1PJ7A 3HOVC 3M4OC 4DDQA 3S16C 2VUMA 4BBRC 1IQ0A 1HQMA 2R92C 3GTGA 1R9TC 4AYBD 2R93C 5C4JC 3RZOK 3TFJA 3FHZA 3HXAA 2CFAB 1VRQC 1YNJA 5FLMC 1DCPA 1ZXOA 2FQOA 2JA7C 4BY1C 4AYBL 2YU9C 4GTEA 3LAPA 4BXXC 4Y52C 4BY7C 1IW7A 3S2HK 3GTLA 3S14C 1Y1WA 2NVYK 2JH3A 4M1XA 4A3BK 2NVXK 1EFWA 1TWHA 3HOVK 3GTMA 3AD7C 1I3QC 1AB4A 4A3KC 3S1MK 2B63K 1DCHA 3S2DK 1XXAA 3BP3A 4YG2A 4OIOA 3V4GA 3ADAC 4GTDA 1EH1A 4C3JC 1PJ6A 3K7AC 1O2BA 4MEYA 3GTQK 4KAWX 4WILA 2O5JA 5M5YK 3Q3QA 3HOWC 1SFOA 4G7ZA 5C4XC 4A3CC 1Y1VA 1J6XA 5C44K 2E2IK 2GSUA 4XLPA 1IL2A 1BS2A 3S17K 1I50K 1ZVUA 4BKWA 2GSOA 3BP8C 2JA8K 3GTKC 1TWGA 3I4NC 3CQZA 1HI9A 1VJEA 5FJ8K 3S0XA 1GE9A 3GDZA 3JSTA 4A93C 4Q5SA 1EQRA 1YNNA 4WJ4A 2VUMC 1O2FB 1L0WA 1TWAK 3TFIA 3M3YK 2WAQD 3AQOA 1K83A 2A69A 3GTGC 3HOUC 1O29A 3T01A 3HOZC 1WORA 5JFEA 2GSNA 2JA6K 4Y7NC 1BJTA 3S1NK 4RMFA 4QIWD 3PO2K 1JQWA 4KB2A 1O25A 4XSZA 2E2HK 4LJZA 5IP7K 5IYDK 3A8KA 1USOA 5IYCC 4QIWL 1Y1WC 4KN4A 4A93K 2JA5K 1BGWA 1TWHC 3GTMC 1WOOA 1TWFA 4C3IK 4C45A 4BBSC 2NVQC 4A3LK 4BLAA 3ERED 1XXCA 3HOXK 3H0GK 4WJ3M 1WSVA 5C3EC 1XPPA 3G4CA 2NVTK 4Y7NK 2KWAA 4A3FK 4O2DA 1INNA 5IOSA 3OEPA 3GTPA 2PPBA 1SFOC 4KMDA 3LPXA 4LR2A 2PMZD 1TWCK 4X6AK 3AH5A 5M5XK 4LK1A 3GTOC 2PA8D 4ZH4A 5IOQA 5M3FK 2V6TA 4QJVB 3FKIC 1XZPB 3GTJK 4XSXA 3DXJA 1TWGC 1ZQ1C 4FZBA 4J3NA 1UV7A 1YCLA 5IOTA 2PMZL 2P8TA 2P5MA 1WQHA 4A3MC 2NVQK 1IBAA 1F7VA 2PA8L 4G0WA 5TMCA 4GFQA 1WQFA 4A3JC 3GSIA 1K83C 2RGRA 2R7ZA 1B4BA 1ZYRA 3M4OK 3GEEA 4P9SA 3S16K 4LOWA 3L4KA 2V6UA 5L46A 4BBRK 1O2AA 3AQPA 1WCMC 5IYBC 4P5AA 3WODA 2R92K 1R9TK 2R93K 2GAGC 5C4JK 1RU0A 1O26A 1VH2A 3GTOK 4A3GC 4KMHA 3SZZA 4NOIA 5FLMK 3S1RC 3FKIK 2V6SA 4A3EC 3GTJA 5M5WK 3PO3C 2ZUEA 2JA7K 4BY1K 4KDDA 2YU9K 2A6HA 1TWFC 4BXXK 2PHCB
chains in the Genus database with same CATH topology
1DCOA 1USMA 1RU0A 3JSTA 1DCPA 2V6TA 2V6SA 3HXAA 4LOWA 4C45A 2EBBA 1USOA 2V6UA 1F93A 1DCHA 4WILA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DCO A;  1USM A;  1RU0 A;  3JST A;  1DCP A;  2V6T A;  2V6S A;  3HXA A;  4LOW A;  4C45 A;  2EBB A;  1USO A;  2V6U A;  1F93 A;  1DCH A;  4WIL A; 
#chains in the Genus database with same CATH topology
 4Y52 K;  4BY7 K;  4BLB A;  1JVI A;  3RZD C;  2NVY A;  4A3J K;  3S14 K;  2NVX A;  3T02 A;  2E2J C;  1DCO A;  1WIH A;  4KM9 A;  2XCR B;  1I3Q K;  4JK1 A;  2B63 A;  1O28 A;  4C2M C;  4A3K K;  3HOY C;  3BUE A;  5CHP A;  4AH6 A;  1F9N A;  3GTP C;  3I4M C;  4KAS A;  3H3V D;  2R93 A;  4C3J K;  1VLO A;  3K7A K;  3OPF A;  3GTQ A;  1DD5 A;  4LQY A;  3GIR A;  3TFH A;  4P5B A;  4OIR A;  4A3E K;  3HOW K;  4GTC A;  3H3V L;  5C4X K;  1ISE A;  1I6V A;  4A3C K;  4C3H C;  1XZQ A;  2WAQ L;  5D4D A;  2E2I A;  4ILD A;  1WOS A;  2WB1 D;  4MQ9 A;  3S1Q C;  1I50 A;  4MEX A;  5CJ9 A;  2GAH C;  2ZUF A;  3GTK K;  4QJV A;  3I4N K;  1YX2 A;  1VGX A;  3GEI A;  2D6F C;  1XZP A;  3GTL C;  2R7Z C;  4A3D C;  3A8I A;  2VUM K;  4OIP A;  1KQ4 A;  1TWA A;  3I4M K;  3QX3 A;  3GTG K;  3HOU K;  3RZO C;  2RH6 A;  1WOP A;  2Y0S D;  2Y3P A;  3HOZ K;  2JA6 A;  4A3I C;  2FQT A;  4GTA A;  2A6E A;  4LK0 A;  5HL8 A;  4KMA A;  4GT9 A;  1F93 A;  5IOR A;  1XZQ B;  2E2H A;  2Y0S L;  1Y1V C;  3AD8 C;  4PAA A;  4GZY A;  3TTG A;  3S2H C;  4G7H A;  5IYC K;  4A3B C;  3MML B;  3GTL K;  1Y1W K;  2JA5 A;  2W7V A;  1USM A;  3CQZ C;  3T00 A;  4KC6 A;  1TWH K;  3GTM K;  1V5V A;  5M3M K;  3S1M C;  4GTL A;  2B63 C;  4BBS K;  3S2D C;  1F7U A;  4KB4 A;  3S15 C;  1IE0 A;  1G51 A;  3H0G A;  5C3E K;  3HKZ D;  4FM9 A;  1PJ5 A;  4KM8 A;  4A3I K;  3GTQ C;  3GEH A;  1J98 A;  4KAR A;  4LLG A;  4Q4Z A;  1JOE A;  1C0A A;  1SFO K;  5E68 A;  1EI6 A;  1TWC A;  1XXB A;  5TJ3 A;  3HKZ L;  1Y1V K;  5C44 C;  2E2I C;  2XCO A;  3LAJ A;  3N0C A;  3S17 C;  1I50 C;  2JA8 C;  1TWG K;  2BE5 A;  4G7O A;  3CQZ K;  4YFN A;  4YFK A;  4PAB A;  2CW0 A;  4A3M K;  2O5I A;  4KN7 A;  3S15 K;  1TWA C;  3M3Y C;  1WSR A;  4G0U A;  2XCQ A;  1K83 K;  3AD9 C;  1J6W A;  2JA6 C;  4G0V A;  4OIQ A;  4KAT A;  4GTB A;  3S1N C;  3N3Y A;  1WCM K;  3IPJ A;  5IYB K;  3PO2 C;  3A8J A;  2R92 A;  2EBB A;  1R9T A;  1O24 A;  3ORE A;  4OIN A;  5IP9 C;  3GTO A;  5TMF A;  4A3G K;  2E2H C;  3CAG A;  5IP7 C;  3FKI A;  3S1R K;  5IYD C;  3FOE A;  3PO3 K;  2JA7 A;  5EGH A;  2YU9 A;  1I6H C;  2JA5 C;  5EGE A;  1IS1 A;  4GTF A;  4C3I C;  4XCH A;  3L4J A;  1TWF K;  3FOF A;  4A3L C;  3VA7 A;  3HOX C;  3RZD K;  3NUH A;  3H0G C;  3EQL A;  5JVO A;  2E2J K;  3G4A A;  4XLN A;  1I3Q A;  2NVT C;  4C2M K;  3HOY K;  1B4A A;  1WCM A;  4A3F C;  4KMU A;  3N0B A;  4YFX A;  2WB1 L;  3GTP K;  3SZY A;  5IP9 K;  1TWC C;  4X6A C;  2CFA A;  1O27 A;  1EK8 A;  2A68 A;  3GTJ C;  1I6H K;  1BDF A;  2ZFZ A;  1SMY A;  4C3H K;  1X31 C;  3S1Q K;  1J6V A;  1ZBS A;  3GTK A;  1WQG A;  2NVY C;  2NVX C;  2R7Z K;  4A3D K;  1PJ7 A;  3HOV C;  3M4O C;  4DDQ A;  3S16 C;  2VUM A;  4BBR C;  1IQ0 A;  1HQM A;  2R92 C;  3GTG A;  1R9T C;  4AYB D;  2R93 C;  5C4J C;  3RZO K;  3TFJ A;  3FHZ A;  3HXA A;  2CFA B;  1VRQ C;  1YNJ A;  5FLM C;  1DCP A;  1ZXO A;  2FQO A;  2JA7 C;  4BY1 C;  4AYB L;  2YU9 C;  4GTE A;  3LAP A;  4BXX C;  4Y52 C;  4BY7 C;  1IW7 A;  3S2H K;  3GTL A;  3S14 C;  1Y1W A;  2NVY K;  2JH3 A;  4M1X A;  4A3B K;  2NVX K;  1EFW A;  1TWH A;  3HOV K;  3GTM A;  3AD7 C;  1I3Q C;  1AB4 A;  4A3K C;  3S1M K;  2B63 K;  1DCH A;  3S2D K;  1XXA A;  3BP3 A;  4YG2 A;  4OIO A;  3V4G A;  3ADA C;  4GTD A;  1EH1 A;  4C3J C;  1PJ6 A;  3K7A C;  1O2B A;  4MEY A;  3GTQ K;  4KAW X;  4WIL A;  2O5J A;  5M5Y K;  3Q3Q A;  3HOW C;  1SFO A;  4G7Z A;  5C4X C;  4A3C C;  1Y1V A;  1J6X A;  5C44 K;  2E2I K;  2GSU A;  4XLP A;  1IL2 A;  1BS2 A;  3S17 K;  1I50 K;  1ZVU A;  4BKW A;  2GSO A;  3BP8 C;  2JA8 K;  3GTK C;  1TWG A;  3I4N C;  3CQZ A;  1HI9 A;  1VJE A;  5FJ8 K;  3S0X A;  1GE9 A;  3GDZ A;  3JST A;  4A93 C;  4Q5S A;  1EQR A;  1YNN A;  4WJ4 A;  2VUM C;  1O2F B;  1L0W A;  1TWA K;  3TFI A;  3M3Y K;  2WAQ D;  3AQO A;  1K83 A;  2A69 A;  3GTG C;  3HOU C;  1O29 A;  3T01 A;  3HOZ C;  1WOR A;  5JFE A;  2GSN A;  2JA6 K;  4Y7N C;  1BJT A;  3S1N K;  4RMF A;  4QIW D;  3PO2 K;  1JQW A;  4KB2 A;  1O25 A;  4XSZ A;  2E2H K;  4LJZ A;  5IP7 K;  5IYD K;  3A8K A;  1USO A;  5IYC C;  4QIW L;  1Y1W C;  4KN4 A;  4A93 K;  2JA5 K;  1BGW A;  1TWH C;  3GTM C;  1WOO A;  1TWF A;  4C3I K;  4C45 A;  4BBS C;  2NVQ C;  4A3L K;  4BLA A;  3ERE D;  1XXC A;  3HOX K;  3H0G K;  4WJ3 M;  1WSV A;  5C3E C;  1XPP A;  3G4C A;  2NVT K;  4Y7N K;  2KWA A;  4A3F K;  4O2D A;  1INN A;  5IOS A;  3OEP A;  3GTP A;  2PPB A;  1SFO C;  4KMD A;  3LPX A;  4LR2 A;  2PMZ D;  1TWC K;  4X6A K;  3AH5 A;  5M5X K;  4LK1 A;  3GTO C;  2PA8 D;  4ZH4 A;  5IOQ A;  5M3F K;  2V6T A;  4QJV B;  3FKI C;  1XZP B;  3GTJ K;  4XSX A;  3DXJ A;  1TWG C;  1ZQ1 C;  4FZB A;  4J3N A;  1UV7 A;  1YCL A;  5IOT A;  2PMZ L;  2P8T A;  2P5M A;  1WQH A;  4A3M C;  2NVQ K;  1IBA A;  1F7V A;  2PA8 L;  4G0W A;  5TMC A;  4GFQ A;  1WQF A;  4A3J C;  3GSI A;  1K83 C;  2RGR A;  2R7Z A;  1B4B A;  1ZYR A;  3M4O K;  3GEE A;  4P9S A;  3S16 K;  4LOW A;  3L4K A;  2V6U A;  5L46 A;  4BBR K;  1O2A A;  3AQP A;  1WCM C;  5IYB C;  4P5A A;  3WOD A;  2R92 K;  1R9T K;  2R93 K;  2GAG C;  5C4J K;  1RU0 A;  1O26 A;  1VH2 A;  3GTO K;  4A3G C;  4KMH A;  3SZZ A;  4NOI A;  5FLM K;  3S1R C;  3FKI K;  2V6S A;  4A3E C;  3GTJ A;  5M5W K;  3PO3 C;  2ZUE A;  2JA7 K;  4BY1 K;  4KDD A;  2YU9 K;  2A6H A;  1TWF C;  4BXX K;  2PHC B; 
#chains in the Genus database with same CATH homology
 1DCO A;  1USM A;  1RU0 A;  3JST A;  1DCP A;  2V6T A;  2V6S A;  3HXA A;  4LOW A;  4C45 A;  2EBB A;  1USO A;  2V6U A;  1F93 A;  1DCH A;  4WIL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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