4C45A

Crystal structure of human pterin-4-alpha-carbinolamine dehydratase 2 (pcbd2)
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
99
structure length
99
Chain Sequence
THRLTAEERNQAILDLKAAGWSELSERDAIYKEFSFHNFNQAFGFMSRVALQAEKMNHHPEWFNVYNKVQITLTSHDCGELTKKDVKLAKFIEKAAASV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Human Pterin-4-Alpha- Carbinolamine Dehydratase 2 (Pcbd2)
rcsb
molecule tags Lyase
source organism Homo sapiens
molecule keywords PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE 2
total genus 37
structure length 99
sequence length 99
ec nomenclature ec 4.2.1.96: 4a-hydroxytetrahydrobiopterin dehydratase.
pdb deposition date 2013-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01329 Pterin_4a Pterin 4 alpha carbinolamine dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1360.20 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 Transcriptional coactivator/pterin dehydratase 4c45A00
1F93A 2V6SA 1DCHA 2V6TA 1USOA 3JSTA 4C45A 1RU0A 1DCOA 2EBBA 1USMA 2V6UA 4LOWA 4WILA 3HXAA 1DCPA
chains in the Genus database with same CATH superfamily
4KN7A 1ZBSA 3GTPA 2V6UA 1I3QA 4A3GC 4A3EK 3HOYK 2E2HA 4QIWL 1WQGA 1TWGK 3T01A 2JA5C 3I4NK 3A8IA 4KATA 1DD5A 1WOPA 1VJEA 4BLAA 4YFXA 4BBSC 3S16C 4LQYA 1L0WA 1O27A 3RZOC 3CAGA 3GDZA 1XXBA 4KASA 5M5WK 4XSZA 1O28A 2NVYK 1IL2A 2ZUEA 5HL8A 4A3JC 1WQHA 4KDDA 3HOZK 2NVTK 4GFQA 5C3EK 3GTOC 5CHPA 2R7ZC 1XZPA 1F7UA 3GTJC 1VH2A 3K7AC 3S1QK 3HXAA 3GTLC 2R93A 5M5YK 4XLPA 1EK8A 4KAWX 1C0AA 3GTKA 1XZQA 1TWAC 5M5XK 3HOXC 4KMDA 3A8KA 1TWCA 2JA7C 4A3DC 3GIRA 5IP7K 1I6VA 1IS1A 5IP9C 4A3KK 4ZH4A 4KN4A 3IPJA 5FLMC 4C3JK 3TFHA 4G0VA 1JQWA 4OINA 3AD8C 1I6HK 3FOFA 3GTMK 2W7VA 1WQFA 4AH6A 3BP3A 5IOQA 3TFIA 2PHCB 2JA8K 4AYBL 4OIQA 5IYDK 4NOIA 4P5BA 3FKIC 4XSXA 2YU9A 1R9TK 3S1NK 2JA6C 4G7ZA 3GTQC 2B63C 2PMZD 5C4JK 4X6AK 1EI6A 3RZDC 4BKWA 1YNNA 5IYCK 4A3EC 1J6WA 3HOYC 3S17K 4Y52K 5JVOA 1ZYRA 1TWGC 1XZQB 5TMFA 4GTFA 1TWFA 1YX2A 2JA6A 2P8TA 3I4NC 2A6HA 2PA8D 5FJ8K 2O5JA 2GAGC 4G0UA 1IBAA 3OEPA 1PJ6A 3T02A 3HKZD 4G0WA 5CJ9A 2R92K 4OIPA 2E2IK 3S2HK 3S1RK 1O29A 2NVYC 4P5AA 2JH3A 1BDFA 1SFOA 3AH5A 3PO2K 3HOZC 1WCMA 2NVTC 5C3EC 3GEHA 3VA7A 1O2AA 2E2JK 4M1XA 4QJVA 3S1QC 2BE5A 2ZUFA 1WSRA 3FHZA 3PO3K 1Y1VA 2CW0A 2NVXK 2V6TA 3BP8C 4Q4ZA 1Y1WA 1F9NA 1INNA 1I50K 3CQZK 4A3IK 3DXJA 3GTGA 2PA8L 3LAJA 1KQ4A 4A93K 5IP7C 3EQLA 4GT9A 1EQRA 3HKZL 4GTCA 4A3KC 3AQPA 4C3JC 4A3FK 5M3MK 5EGEA 1ZXOA 4PABA 1XXAA 2VUMK 4DDQA 1I6HC 3GTMC 2JA5A 3TTGA 3S1MK 4BLBA 4A3LK 1ZVUA 2D6FC 2A68A 4C2MK 4GZYA 2XCQA 4C45A 2JA8C 4A3CK 5TJ3A 4KMAA 5IYDC 3M3YK 5D4DA 3H0GK 4G7HA 1R9TC 3S1NC 3HOVK 4AYBD 2RH6A 5C4JC 4X6AC 4QJVB 4GTEA 2A69A 3GTOA 1X31C 2R7ZA 4YFKA 3GTPK 2P5MA 4GTLA 3GTJA 1B4BA 1I3QK 3V4GA 5IYCC 3S17C 3HOUK 3JSTA 1K83K 4Y52C 1DCOA 3AD9C 3GTLA 4BY7K 2XCRB 4KM8A 1HI9A 4KM9A 4WJ4A 1TWAA 3T00A 3SZYA 1RU0A 2WAQD 4LLGA 2R92C 2JA7A 2E2IC 3S2HC 3S1RC 1YCLA 3G4CA 3TFJA 3LAPA 3S15K 1O2FB 3PO2C 3AQOA 2NVQK 3AD7C 1SMYA 1WORA 2KWAA 2E2JC 2RGRA 4OIOA 3GSIA 4ILDA 1J6VA 3PO3C 4KMHA 4LOWA 2R93K 2NVXC 1G51A 4GTBA 2WB1D 3GTKK 1USMA 1I50C 3CQZC 4A3IC 3FKIA 1F93A 4C3HK 4YFNA 1TWCK 4A93C 1AB4A 3GTQA 2B63A 1DCPA 1JVIA 3ERED 2WAQL 2NVXA 1YNJA 5IYBK 3Q3QA 2CFAA 4A3FC 2VUMC 4RMFA 1TWGA 5M3FK 4C3IK 3S1MC 1IE0A 4A3LC 3I4MK 3MMLB 4C2MC 4MEXA 1O2BA 4KMUA 4A3CC 4FM9A 1BS2A 3M3YC 1EH1A 3H0GC 2WB1L 4KB4A 2YU9K 3HOVC 1BGWA 2NVYA 1IQ0A 1WSVA 1V5VA 4A3BK 2ZFZA 3GTPC 3WODA 1I3QC 2Y3PA 3HOUC 2FQOA 4Y7NK 1K83C 2GSUA 4LR2A 3S14K 1O26A 1B4AA 4BY7C 1TWFK 4P9SA 3QX3A 5C4XK 3NUHA 2Y0SD 1VGXA 1TWHK 4Q5SA 5E68A 5EGHA 3HOWK 1XXCA 1K83A 2CFAB 3M4OK 4JK1A 4BBRK 3S15C 4YG2A 1SFOK 4J3NA 2NVQC 1WCMK 3FOEA 3S2DK 3LPXA 4KARA 5C44K 3GTMA 3G4AA 1EFWA 3H3VD 2V6SA 2R93C 1PJ7A 1Y1VK 3GEIA 5JFEA 2O5IA 3OPFA 3GTKC 1Y1WK 4BY1C 1WOOA 1IW7A 2GSOA 2E2HK 4BXXK 2XCOA 3GTGK 4C3HC 1R9TA 2Y0SL 1TWCC 4O2DA 4MEYA 1O25A 4A3MK 1BJTA 5IYBC 1XPPA 4A3GK 4GTAA 4LJZA 4C3IC 3S0XA 2JA5K 3I4MC 5IOSA 4LK1A 3H3VL 4WILA 4BBSK 3S16K 2PPBA 2R92A 3L4JA 3RZOK 2E2IA 3GEEA 4G7OA 2YU9C 1O24A 2A6EA 4KC6A 2GAHC 4A3JK 2GSNA 4A3BC 4BY1K 3GTOK 2R7ZK 3N0CA 3ADAC 2EBBA 3GTJK 3K7AK 4Y7NC 4MQ9A 4FZBA 1F7VA 3GTLK 1UV7A 3S14C 1TWFC 1XZPB 1ZQ1C 1WOSA 5C4XC 1TWAK 1I50A 1TWHC 3CQZA 3N0BA 3N3YA 3HOXK 1ISEA 1PJ5A 4KB2A 1J98A 2JA7K 4A3DK 3HOWC 3L4KA 1HQMA 3M4OC 4BBRC 4WJ3M 5IP9K 3BUEA 4LK0A 1VRQC 1JOEA 5FLMK 1SFOC 4QIWD 2FQTA 1WCMC 1TWHA 3S2DC 4XLNA 2VUMA 4PAAA 5C44C 5TMCA 4XCHA 1Y1VC 3OREA 3A8JA 1WIHA 1J6XA 1GE9A 3SZZA 1Y1WC 2PMZL 2E2HC 1DCHA 4GTDA 3FKIK 3H0GA 4BXXC 1VLOA 5IORA 3GTGC 5IOTA 4OIRA 2JA6K 3GTQK 2B63K 1USOA 4A3MC 3RZDK 5L46A
chains in the Genus database with same CATH topology
1F93A 2V6SA 1DCHA 2V6TA 1USOA 3JSTA 4C45A 1RU0A 1DCOA 2EBBA 1USMA 2V6UA 4LOWA 4WILA 3HXAA 1DCPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1F93 A;  2V6S A;  1DCH A;  2V6T A;  1USO A;  3JST A;  4C45 A;  1RU0 A;  1DCO A;  2EBB A;  1USM A;  2V6U A;  4LOW A;  4WIL A;  3HXA A;  1DCP A; 
#chains in the Genus database with same CATH topology
 4KN7 A;  1ZBS A;  3GTP A;  2V6U A;  1I3Q A;  4A3G C;  4A3E K;  3HOY K;  2E2H A;  4QIW L;  1WQG A;  1TWG K;  3T01 A;  2JA5 C;  3I4N K;  3A8I A;  4KAT A;  1DD5 A;  1WOP A;  1VJE A;  4BLA A;  4YFX A;  4BBS C;  3S16 C;  4LQY A;  1L0W A;  1O27 A;  3RZO C;  3CAG A;  3GDZ A;  1XXB A;  4KAS A;  5M5W K;  4XSZ A;  1O28 A;  2NVY K;  1IL2 A;  2ZUE A;  5HL8 A;  4A3J C;  1WQH A;  4KDD A;  3HOZ K;  2NVT K;  4GFQ A;  5C3E K;  3GTO C;  5CHP A;  2R7Z C;  1XZP A;  1F7U A;  3GTJ C;  1VH2 A;  3K7A C;  3S1Q K;  3HXA A;  3GTL C;  2R93 A;  5M5Y K;  4XLP A;  1EK8 A;  4KAW X;  1C0A A;  3GTK A;  1XZQ A;  1TWA C;  5M5X K;  3HOX C;  4KMD A;  3A8K A;  1TWC A;  2JA7 C;  4A3D C;  3GIR A;  5IP7 K;  1I6V A;  1IS1 A;  5IP9 C;  4A3K K;  4ZH4 A;  4KN4 A;  3IPJ A;  5FLM C;  4C3J K;  3TFH A;  4G0V A;  1JQW A;  4OIN A;  3AD8 C;  1I6H K;  3FOF A;  3GTM K;  2W7V A;  1WQF A;  4AH6 A;  3BP3 A;  5IOQ A;  3TFI A;  2PHC B;  2JA8 K;  4AYB L;  4OIQ A;  5IYD K;  4NOI A;  4P5B A;  3FKI C;  4XSX A;  2YU9 A;  1R9T K;  3S1N K;  2JA6 C;  4G7Z A;  3GTQ C;  2B63 C;  2PMZ D;  5C4J K;  4X6A K;  1EI6 A;  3RZD C;  4BKW A;  1YNN A;  5IYC K;  4A3E C;  1J6W A;  3HOY C;  3S17 K;  4Y52 K;  5JVO A;  1ZYR A;  1TWG C;  1XZQ B;  5TMF A;  4GTF A;  1TWF A;  1YX2 A;  2JA6 A;  2P8T A;  3I4N C;  2A6H A;  2PA8 D;  5FJ8 K;  2O5J A;  2GAG C;  4G0U A;  1IBA A;  3OEP A;  1PJ6 A;  3T02 A;  3HKZ D;  4G0W A;  5CJ9 A;  2R92 K;  4OIP A;  2E2I K;  3S2H K;  3S1R K;  1O29 A;  2NVY C;  4P5A A;  2JH3 A;  1BDF A;  1SFO A;  3AH5 A;  3PO2 K;  3HOZ C;  1WCM A;  2NVT C;  5C3E C;  3GEH A;  3VA7 A;  1O2A A;  2E2J K;  4M1X A;  4QJV A;  3S1Q C;  2BE5 A;  2ZUF A;  1WSR A;  3FHZ A;  3PO3 K;  1Y1V A;  2CW0 A;  2NVX K;  2V6T A;  3BP8 C;  4Q4Z A;  1Y1W A;  1F9N A;  1INN A;  1I50 K;  3CQZ K;  4A3I K;  3DXJ A;  3GTG A;  2PA8 L;  3LAJ A;  1KQ4 A;  4A93 K;  5IP7 C;  3EQL A;  4GT9 A;  1EQR A;  3HKZ L;  4GTC A;  4A3K C;  3AQP A;  4C3J C;  4A3F K;  5M3M K;  5EGE A;  1ZXO A;  4PAB A;  1XXA A;  2VUM K;  4DDQ A;  1I6H C;  3GTM C;  2JA5 A;  3TTG A;  3S1M K;  4BLB A;  4A3L K;  1ZVU A;  2D6F C;  2A68 A;  4C2M K;  4GZY A;  2XCQ A;  4C45 A;  2JA8 C;  4A3C K;  5TJ3 A;  4KMA A;  5IYD C;  3M3Y K;  5D4D A;  3H0G K;  4G7H A;  1R9T C;  3S1N C;  3HOV K;  4AYB D;  2RH6 A;  5C4J C;  4X6A C;  4QJV B;  4GTE A;  2A69 A;  3GTO A;  1X31 C;  2R7Z A;  4YFK A;  3GTP K;  2P5M A;  4GTL A;  3GTJ A;  1B4B A;  1I3Q K;  3V4G A;  5IYC C;  3S17 C;  3HOU K;  3JST A;  1K83 K;  4Y52 C;  1DCO A;  3AD9 C;  3GTL A;  4BY7 K;  2XCR B;  4KM8 A;  1HI9 A;  4KM9 A;  4WJ4 A;  1TWA A;  3T00 A;  3SZY A;  1RU0 A;  2WAQ D;  4LLG A;  2R92 C;  2JA7 A;  2E2I C;  3S2H C;  3S1R C;  1YCL A;  3G4C A;  3TFJ A;  3LAP A;  3S15 K;  1O2F B;  3PO2 C;  3AQO A;  2NVQ K;  3AD7 C;  1SMY A;  1WOR A;  2KWA A;  2E2J C;  2RGR A;  4OIO A;  3GSI A;  4ILD A;  1J6V A;  3PO3 C;  4KMH A;  4LOW A;  2R93 K;  2NVX C;  1G51 A;  4GTB A;  2WB1 D;  3GTK K;  1USM A;  1I50 C;  3CQZ C;  4A3I C;  3FKI A;  1F93 A;  4C3H K;  4YFN A;  1TWC K;  4A93 C;  1AB4 A;  3GTQ A;  2B63 A;  1DCP A;  1JVI A;  3ERE D;  2WAQ L;  2NVX A;  1YNJ A;  5IYB K;  3Q3Q A;  2CFA A;  4A3F C;  2VUM C;  4RMF A;  1TWG A;  5M3F K;  4C3I K;  3S1M C;  1IE0 A;  4A3L C;  3I4M K;  3MML B;  4C2M C;  4MEX A;  1O2B A;  4KMU A;  4A3C C;  4FM9 A;  1BS2 A;  3M3Y C;  1EH1 A;  3H0G C;  2WB1 L;  4KB4 A;  2YU9 K;  3HOV C;  1BGW A;  2NVY A;  1IQ0 A;  1WSV A;  1V5V A;  4A3B K;  2ZFZ A;  3GTP C;  3WOD A;  1I3Q C;  2Y3P A;  3HOU C;  2FQO A;  4Y7N K;  1K83 C;  2GSU A;  4LR2 A;  3S14 K;  1O26 A;  1B4A A;  4BY7 C;  1TWF K;  4P9S A;  3QX3 A;  5C4X K;  3NUH A;  2Y0S D;  1VGX A;  1TWH K;  4Q5S A;  5E68 A;  5EGH A;  3HOW K;  1XXC A;  1K83 A;  2CFA B;  3M4O K;  4JK1 A;  4BBR K;  3S15 C;  4YG2 A;  1SFO K;  4J3N A;  2NVQ C;  1WCM K;  3FOE A;  3S2D K;  3LPX A;  4KAR A;  5C44 K;  3GTM A;  3G4A A;  1EFW A;  3H3V D;  2V6S A;  2R93 C;  1PJ7 A;  1Y1V K;  3GEI A;  5JFE A;  2O5I A;  3OPF A;  3GTK C;  1Y1W K;  4BY1 C;  1WOO A;  1IW7 A;  2GSO A;  2E2H K;  4BXX K;  2XCO A;  3GTG K;  4C3H C;  1R9T A;  2Y0S L;  1TWC C;  4O2D A;  4MEY A;  1O25 A;  4A3M K;  1BJT A;  5IYB C;  1XPP A;  4A3G K;  4GTA A;  4LJZ A;  4C3I C;  3S0X A;  2JA5 K;  3I4M C;  5IOS A;  4LK1 A;  3H3V L;  4WIL A;  4BBS K;  3S16 K;  2PPB A;  2R92 A;  3L4J A;  3RZO K;  2E2I A;  3GEE A;  4G7O A;  2YU9 C;  1O24 A;  2A6E A;  4KC6 A;  2GAH C;  4A3J K;  2GSN A;  4A3B C;  4BY1 K;  3GTO K;  2R7Z K;  3N0C A;  3ADA C;  2EBB A;  3GTJ K;  3K7A K;  4Y7N C;  4MQ9 A;  4FZB A;  1F7V A;  3GTL K;  1UV7 A;  3S14 C;  1TWF C;  1XZP B;  1ZQ1 C;  1WOS A;  5C4X C;  1TWA K;  1I50 A;  1TWH C;  3CQZ A;  3N0B A;  3N3Y A;  3HOX K;  1ISE A;  1PJ5 A;  4KB2 A;  1J98 A;  2JA7 K;  4A3D K;  3HOW C;  3L4K A;  1HQM A;  3M4O C;  4BBR C;  4WJ3 M;  5IP9 K;  3BUE A;  4LK0 A;  1VRQ C;  1JOE A;  5FLM K;  1SFO C;  4QIW D;  2FQT A;  1WCM C;  1TWH A;  3S2D C;  4XLN A;  2VUM A;  4PAA A;  5C44 C;  5TMC A;  4XCH A;  1Y1V C;  3ORE A;  3A8J A;  1WIH A;  1J6X A;  1GE9 A;  3SZZ A;  1Y1W C;  2PMZ L;  2E2H C;  1DCH A;  4GTD A;  3FKI K;  3H0G A;  4BXX C;  1VLO A;  5IOR A;  3GTG C;  5IOT A;  4OIR A;  2JA6 K;  3GTQ K;  2B63 K;  1USO A;  4A3M C;  3RZD K;  5L46 A; 
#chains in the Genus database with same CATH homology
 1F93 A;  2V6S A;  1DCH A;  2V6T A;  1USO A;  3JST A;  4C45 A;  1RU0 A;  1DCO A;  2EBB A;  1USM A;  2V6U A;  4LOW A;  4WIL A;  3HXA A;  1DCP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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