4C45A

Crystal structure of human pterin-4-alpha-carbinolamine dehydratase 2 (pcbd2)
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
99
structure length
99
Chain Sequence
THRLTAEERNQAILDLKAAGWSELSERDAIYKEFSFHNFNQAFGFMSRVALQAEKMNHHPEWFNVYNKVQITLTSHDCGELTKKDVKLAKFIEKAAASV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Human Pterin-4-Alpha- Carbinolamine Dehydratase 2 (Pcbd2)
rcsb
molecule tags Lyase
source organism Homo sapiens
molecule keywords PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE 2
total genus 37
structure length 99
sequence length 99
ec nomenclature ec 4.2.1.96: 4a-hydroxytetrahydrobiopterin dehydratase.
pdb deposition date 2013-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01329 Pterin_4a Pterin 4 alpha carbinolamine dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1360.20 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 Transcriptional coactivator/pterin dehydratase 4c45A00
2V6TA 2EBBA 4C45A 1DCHA 1USMA 1USOA 4WILA 3JSTA 3HXAA 1RU0A 2V6UA 4LOWA 1F93A 2V6SA 1DCOA 1DCPA
chains in the Genus database with same CATH superfamily
4A3MK 4A3EC 1AB4A 5JVOA 5M5YK 2R93K 4LOWA 1O25A 4G7ZA 2JA5C 3S1MK 1XZQB 5CHPA 1XPPA 1J6WA 4A3BK 1Y1WA 2JA5K 1O29A 1EI6A 5EGHA 3CQZA 3HOZC 1O2AA 3DXJA 1WQGA 1XZPB 3L4KA 4X6AK 4C2MC 1TWAA 2E2IC 3S1QC 3HOZK 4Q5SA 1EQRA 2R7ZA 2B63A 4MQ9A 1EK8A 4MEXA 4GTLA 4BKWA 2ZFZA 2EBBA 2E2IK 3A8JA 1WSVA 2GSUA 4XSXA 4QJVB 5IOSA 3GTJC 1KQ4A 3GTKA 4FZBA 2NVXA 3A8IA 3N0BA 3S2DC 3NUHA 3TFIA 3GTJK 3AD7C 4BY1C 5IOTA 2PHCB 3S2DK 1WCMA 4LK1A 1YNJA 1WIHA 3WODA 2V6UA 4BY1K 3GTMC 2V6TA 2XCQA 2R92A 2YU9C 1K83A 2A68A 1HQMA 4A3KC 3OREA 3GTMK 1TWGC 2W7VA 3HOUC 3AQOA 4G7HA 5IYDC 1I3QC 3GSIA 2YU9K 4J3NA 1VLOA 2CFAA 4KN7A 4A3KK 3GTGA 1IE0A 1TWFC 5IOQA 3ERED 1TWGK 4BXXC 4WJ3M 3HOUK 4KB2A 3AD8C 2WAQD 4KARA 1ZQ1C 2FQOA 2P5MA 1TWFK 1X31C 4BXXK 3K7AK 3IPJA 1I50C 3V4GA 1WOSA 3S2HC 3PO2C 1IS1A 1F93A 4KMAA 2VUMK 3S17C 1I50K 3S2HK 2KWAA 3HOYC 2E2HC 4BBSK 1IL2A 1VGXA 3HOWC 4GTAA 3PO2K 3BUEA 4P5BA 3TFHA 3GTPK 4G0WA 2E2HK 5E68A 4PABA 3I4MK 4A3DK 2NVYK 1Y1VC 4LQYA 5IP9K 1O28A 3GTLA 1IQ0A 3AD9C 1DCHA 4AYBL 2JA7C 4A3CC 2GAHC 4BLAA 4OIRA 1PJ7A 2JA7K 4A3CK 1J6XA 3GIRA 3RZOC 3FOEA 4OINA 5IP7C 4A3JC 5M3FK 2V6SA 3VA7A 4YFXA 3LAPA 3GTQA 3RZOK 4AYBD 4KMUA 5IP7K 2JA6C 2RGRA 1JVIA 2R93A 4A3EK 2O5JA 2JA6K 2A69A 1ZBSA 2ZUEA 1O2FB 2JA5A 3M4OC 1TWCC 5L46A 1Y1WC 3T02A 1TWCK 3BP3A 3JSTA 4LR2A 4OIOA 2XCRB 1F7VA 4C2MK 4GTBA 3OPFA 4LJZA 3GTOC 5C44C 3S1QK 3HOVC 1TWAC 4KATA 4KMHA 2R7ZC 1IW7A 2E2IA 4GTCA 3GTOK 3ADAC 3CAGA 4KN4A 1L0WA 3HOVK 1VJEA 3H0GC 3QX3A 2O5IA 4GTEA 3GTJA 3H0GK 1PJ5A 1XXAA 4GTFA 1USOA 3G4AA 3SZZA 1YX2A 2PPBA 2CW0A 5IORA 1BGWA 3AH5A 1RU0A 4OIPA 1SFOC 1JOEA 4A93C 1DD5A 3PO3C 4Q4ZA 4YFKA 4G0UA 4KM8A 1GE9A 1WOOA 3S14C 1TWHC 5TMCA 1SFOK 3GTMA 4P5AA 4A93K 4A3LC 3PO3K 2R92C 1YNNA 4OIQA 1O24A 3S1RC 5C3EC 2YU9A 2JA8C 4XCHA 3S14K 4O2DA 5IYDK 1I3QK 1TWHK 1TWGA 1J98A 4A3LK 1YCLA 2P8TA 2PA8L 3S1RK 5C3EK 3GTGC 1O2BA 5M5XK 1TWFA 5C4JC 1INNA 2CFAB 4G0VA 2NVTC 1J6VA 3I4NC 4XLPA 1EFWA 2VUMA 4A3FC 1O27A 1I50A 3HOXC 1BS2A 1I6VA 2NVTK 3S17K 2RH6A 3LPXA 3T00A 3HOYK 4GT9A 3I4NK 1R9TC 2GAGC 2Y3PA 4KAWX 1WSRA 3HOWK 3N0CA 3GTPA 1SMYA 2E2HA 4KMDA 1R9TK 2NVYA 1V5VA 1Y1VK 4Y52C 4G7OA 1B4AA 3GTLC 1BJTA 3LAJA 1IBAA 1WQHA 4Y52K 4WILA 2JA7A 5IYCC 3S16C 1EH1A 3L4JA 3FKIC 1O26A 5IYCK 4A3JK 1UV7A 3S16K 3S1NC 1VRQC 4LLGA 3FKIK 3GTQC 5IYBC 5TMFA 1VH2A 1XZQA 2D6FC 1F9NA 1JQWA 4WJ4A 2JA6A 3S1MC 4GZYA 1WQFA 3BP8C 3GEEA 2GSNA 4BY7C 4C45A 4XSZA 3S0XA 1XXBA 3M4OK 4QIWL 3CQZC 2JH3A 4DDQA 1XZPA 4A3BC 1XXCA 5M3MK 1Y1WK 1TWCA 4BY7K 5CJ9A 2WB1L 3CQZK 4GFQA 4X6AC 1PJ6A 2B63C 5C44K 3MMLB 1TWAK 1I6HC 4KB4A 3Q3QA 4M1XA 4QJVA 2R7ZK 4QIWD 2B63K 4C3JC 1USMA 3GTOA 3T01A 3FHZA 3GTKC 1F7UA 1I6HK 2BE5A 5JFEA 2WB1D 4C3JK 2NVXC 4PAAA 3H0GA 3A8KA 3GEIA 3OEPA 3TTGA 3GTKK 2NVXK 4GTDA 1WCMC 2NVQC 4KC6A 2PMZL 4BLBA 1G51A 4NOIA 5HL8A 1WCMK 2NVQK 2E2JC 3H3VL 1K83C 2Y0SL 1SFOA 4C3IC 4A3IC 3FOFA 3HXAA 2R92K 4YG2A 2E2JK 1K83K 1I3QA 1TWHA 2WAQL 2FQTA 2JA8K 4C3IK 4LK0A 5TJ3A 4A3IK 1HI9A 4ZH4A 5M5WK 2A6EA 2PMZD 3TFJA 3GTGK 3H3VD 2Y0SD 1B4BA 5C4JK 4XLNA 3HKZL 4KDDA 3K7AC 1C0AA 1BDFA 1ZVUA 2PA8D 1ISEA 3RZDC 3EQLA 4AH6A 4KM9A 1WOPA 2A6HA 4KASA 4A3FK 3HOXK 4BBRC 2VUMC 3GDZA 3RZDK 4FM9A 4BBSC 3S15C 4BBRK 1R9TA 4A3GC 3GTPC 1DCPA 3AQPA 3HKZD 5C4XC 2ZUFA 1WORA 1Y1VA 3S15K 3GEHA 3I4MC 4A3DC 2NVYC 4A3GK 3G4CA 3M3YC 1ZXOA 5IP9C 5C4XK 4Y7NC 3GTLK 5FLMC 4RMFA 3M3YK 4MEYA 5D4DA 4Y7NK 4JK1A 5EGEA 5FLMK 3N3YA 3SZYA 1ZYRA 4C3HC 3FKIA 4YFNA 4A3MC 2XCOA 5FJ8K 3S1NK 4ILDA 2R93C 2GSOA 3GTQK 5IYBK 4C3HK 4P9SA 1DCOA
chains in the Genus database with same CATH topology
2V6TA 2EBBA 4C45A 1DCHA 1USMA 1USOA 4WILA 3JSTA 3HXAA 1RU0A 2V6UA 4LOWA 1F93A 2V6SA 1DCOA 1DCPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2V6T A;  2EBB A;  4C45 A;  1DCH A;  1USM A;  1USO A;  4WIL A;  3JST A;  3HXA A;  1RU0 A;  2V6U A;  4LOW A;  1F93 A;  2V6S A;  1DCO A;  1DCP A; 
#chains in the Genus database with same CATH topology
 4A3M K;  4A3E C;  1AB4 A;  5JVO A;  5M5Y K;  2R93 K;  4LOW A;  1O25 A;  4G7Z A;  2JA5 C;  3S1M K;  1XZQ B;  5CHP A;  1XPP A;  1J6W A;  4A3B K;  1Y1W A;  2JA5 K;  1O29 A;  1EI6 A;  5EGH A;  3CQZ A;  3HOZ C;  1O2A A;  3DXJ A;  1WQG A;  1XZP B;  3L4K A;  4X6A K;  4C2M C;  1TWA A;  2E2I C;  3S1Q C;  3HOZ K;  4Q5S A;  1EQR A;  2R7Z A;  2B63 A;  4MQ9 A;  1EK8 A;  4MEX A;  4GTL A;  4BKW A;  2ZFZ A;  2EBB A;  2E2I K;  3A8J A;  1WSV A;  2GSU A;  4XSX A;  4QJV B;  5IOS A;  3GTJ C;  1KQ4 A;  3GTK A;  4FZB A;  2NVX A;  3A8I A;  3N0B A;  3S2D C;  3NUH A;  3TFI A;  3GTJ K;  3AD7 C;  4BY1 C;  5IOT A;  2PHC B;  3S2D K;  1WCM A;  4LK1 A;  1YNJ A;  1WIH A;  3WOD A;  2V6U A;  4BY1 K;  3GTM C;  2V6T A;  2XCQ A;  2R92 A;  2YU9 C;  1K83 A;  2A68 A;  1HQM A;  4A3K C;  3ORE A;  3GTM K;  1TWG C;  2W7V A;  3HOU C;  3AQO A;  4G7H A;  5IYD C;  1I3Q C;  3GSI A;  2YU9 K;  4J3N A;  1VLO A;  2CFA A;  4KN7 A;  4A3K K;  3GTG A;  1IE0 A;  1TWF C;  5IOQ A;  3ERE D;  1TWG K;  4BXX C;  4WJ3 M;  3HOU K;  4KB2 A;  3AD8 C;  2WAQ D;  4KAR A;  1ZQ1 C;  2FQO A;  2P5M A;  1TWF K;  1X31 C;  4BXX K;  3K7A K;  3IPJ A;  1I50 C;  3V4G A;  1WOS A;  3S2H C;  3PO2 C;  1IS1 A;  1F93 A;  4KMA A;  2VUM K;  3S17 C;  1I50 K;  3S2H K;  2KWA A;  3HOY C;  2E2H C;  4BBS K;  1IL2 A;  1VGX A;  3HOW C;  4GTA A;  3PO2 K;  3BUE A;  4P5B A;  3TFH A;  3GTP K;  4G0W A;  2E2H K;  5E68 A;  4PAB A;  3I4M K;  4A3D K;  2NVY K;  1Y1V C;  4LQY A;  5IP9 K;  1O28 A;  3GTL A;  1IQ0 A;  3AD9 C;  1DCH A;  4AYB L;  2JA7 C;  4A3C C;  2GAH C;  4BLA A;  4OIR A;  1PJ7 A;  2JA7 K;  4A3C K;  1J6X A;  3GIR A;  3RZO C;  3FOE A;  4OIN A;  5IP7 C;  4A3J C;  5M3F K;  2V6S A;  3VA7 A;  4YFX A;  3LAP A;  3GTQ A;  3RZO K;  4AYB D;  4KMU A;  5IP7 K;  2JA6 C;  2RGR A;  1JVI A;  2R93 A;  4A3E K;  2O5J A;  2JA6 K;  2A69 A;  1ZBS A;  2ZUE A;  1O2F B;  2JA5 A;  3M4O C;  1TWC C;  5L46 A;  1Y1W C;  3T02 A;  1TWC K;  3BP3 A;  3JST A;  4LR2 A;  4OIO A;  2XCR B;  1F7V A;  4C2M K;  4GTB A;  3OPF A;  4LJZ A;  3GTO C;  5C44 C;  3S1Q K;  3HOV C;  1TWA C;  4KAT A;  4KMH A;  2R7Z C;  1IW7 A;  2E2I A;  4GTC A;  3GTO K;  3ADA C;  3CAG A;  4KN4 A;  1L0W A;  3HOV K;  1VJE A;  3H0G C;  3QX3 A;  2O5I A;  4GTE A;  3GTJ A;  3H0G K;  1PJ5 A;  1XXA A;  4GTF A;  1USO A;  3G4A A;  3SZZ A;  1YX2 A;  2PPB A;  2CW0 A;  5IOR A;  1BGW A;  3AH5 A;  1RU0 A;  4OIP A;  1SFO C;  1JOE A;  4A93 C;  1DD5 A;  3PO3 C;  4Q4Z A;  4YFK A;  4G0U A;  4KM8 A;  1GE9 A;  1WOO A;  3S14 C;  1TWH C;  5TMC A;  1SFO K;  3GTM A;  4P5A A;  4A93 K;  4A3L C;  3PO3 K;  2R92 C;  1YNN A;  4OIQ A;  1O24 A;  3S1R C;  5C3E C;  2YU9 A;  2JA8 C;  4XCH A;  3S14 K;  4O2D A;  5IYD K;  1I3Q K;  1TWH K;  1TWG A;  1J98 A;  4A3L K;  1YCL A;  2P8T A;  2PA8 L;  3S1R K;  5C3E K;  3GTG C;  1O2B A;  5M5X K;  1TWF A;  5C4J C;  1INN A;  2CFA B;  4G0V A;  2NVT C;  1J6V A;  3I4N C;  4XLP A;  1EFW A;  2VUM A;  4A3F C;  1O27 A;  1I50 A;  3HOX C;  1BS2 A;  1I6V A;  2NVT K;  3S17 K;  2RH6 A;  3LPX A;  3T00 A;  3HOY K;  4GT9 A;  3I4N K;  1R9T C;  2GAG C;  2Y3P A;  4KAW X;  1WSR A;  3HOW K;  3N0C A;  3GTP A;  1SMY A;  2E2H A;  4KMD A;  1R9T K;  2NVY A;  1V5V A;  1Y1V K;  4Y52 C;  4G7O A;  1B4A A;  3GTL C;  1BJT A;  3LAJ A;  1IBA A;  1WQH A;  4Y52 K;  4WIL A;  2JA7 A;  5IYC C;  3S16 C;  1EH1 A;  3L4J A;  3FKI C;  1O26 A;  5IYC K;  4A3J K;  1UV7 A;  3S16 K;  3S1N C;  1VRQ C;  4LLG A;  3FKI K;  3GTQ C;  5IYB C;  5TMF A;  1VH2 A;  1XZQ A;  2D6F C;  1F9N A;  1JQW A;  4WJ4 A;  2JA6 A;  3S1M C;  4GZY A;  1WQF A;  3BP8 C;  3GEE A;  2GSN A;  4BY7 C;  4C45 A;  4XSZ A;  3S0X A;  1XXB A;  3M4O K;  4QIW L;  3CQZ C;  2JH3 A;  4DDQ A;  1XZP A;  4A3B C;  1XXC A;  5M3M K;  1Y1W K;  1TWC A;  4BY7 K;  5CJ9 A;  2WB1 L;  3CQZ K;  4GFQ A;  4X6A C;  1PJ6 A;  2B63 C;  5C44 K;  3MML B;  1TWA K;  1I6H C;  4KB4 A;  3Q3Q A;  4M1X A;  4QJV A;  2R7Z K;  4QIW D;  2B63 K;  4C3J C;  1USM A;  3GTO A;  3T01 A;  3FHZ A;  3GTK C;  1F7U A;  1I6H K;  2BE5 A;  5JFE A;  2WB1 D;  4C3J K;  2NVX C;  4PAA A;  3H0G A;  3A8K A;  3GEI A;  3OEP A;  3TTG A;  3GTK K;  2NVX K;  4GTD A;  1WCM C;  2NVQ C;  4KC6 A;  2PMZ L;  4BLB A;  1G51 A;  4NOI A;  5HL8 A;  1WCM K;  2NVQ K;  2E2J C;  3H3V L;  1K83 C;  2Y0S L;  1SFO A;  4C3I C;  4A3I C;  3FOF A;  3HXA A;  2R92 K;  4YG2 A;  2E2J K;  1K83 K;  1I3Q A;  1TWH A;  2WAQ L;  2FQT A;  2JA8 K;  4C3I K;  4LK0 A;  5TJ3 A;  4A3I K;  1HI9 A;  4ZH4 A;  5M5W K;  2A6E A;  2PMZ D;  3TFJ A;  3GTG K;  3H3V D;  2Y0S D;  1B4B A;  5C4J K;  4XLN A;  3HKZ L;  4KDD A;  3K7A C;  1C0A A;  1BDF A;  1ZVU A;  2PA8 D;  1ISE A;  3RZD C;  3EQL A;  4AH6 A;  4KM9 A;  1WOP A;  2A6H A;  4KAS A;  4A3F K;  3HOX K;  4BBR C;  2VUM C;  3GDZ A;  3RZD K;  4FM9 A;  4BBS C;  3S15 C;  4BBR K;  1R9T A;  4A3G C;  3GTP C;  1DCP A;  3AQP A;  3HKZ D;  5C4X C;  2ZUF A;  1WOR A;  1Y1V A;  3S15 K;  3GEH A;  3I4M C;  4A3D C;  2NVY C;  4A3G K;  3G4C A;  3M3Y C;  1ZXO A;  5IP9 C;  5C4X K;  4Y7N C;  3GTL K;  5FLM C;  4RMF A;  3M3Y K;  4MEY A;  5D4D A;  4Y7N K;  4JK1 A;  5EGE A;  5FLM K;  3N3Y A;  3SZY A;  1ZYR A;  4C3H C;  3FKI A;  4YFN A;  4A3M C;  2XCO A;  5FJ8 K;  3S1N K;  4ILD A;  2R93 C;  2GSO A;  3GTQ K;  5IYB K;  4C3H K;  4P9S A;  1DCO A; 
#chains in the Genus database with same CATH homology
 2V6T A;  2EBB A;  4C45 A;  1DCH A;  1USM A;  1USO A;  4WIL A;  3JST A;  3HXA A;  1RU0 A;  2V6U A;  4LOW A;  1F93 A;  2V6S A;  1DCO A;  1DCP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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