4C45A

Crystal structure of human pterin-4-alpha-carbinolamine dehydratase 2 (pcbd2)
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
99
structure length
99
Chain Sequence
THRLTAEERNQAILDLKAAGWSELSERDAIYKEFSFHNFNQAFGFMSRVALQAEKMNHHPEWFNVYNKVQITLTSHDCGELTKKDVKLAKFIEKAAASV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Human Pterin-4-Alpha- Carbinolamine Dehydratase 2 (Pcbd2)
rcsb
molecule tags Lyase
source organism Homo sapiens
molecule keywords PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE 2
total genus 37
structure length 99
sequence length 99
ec nomenclature ec 4.2.1.96: 4a-hydroxytetrahydrobiopterin dehydratase.
pdb deposition date 2013-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01329 Pterin_4a Pterin 4 alpha carbinolamine dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1360.20 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 Transcriptional coactivator/pterin dehydratase 4c45A00
1DCOA 1USMA 2V6SA 1DCHA 2V6TA 1F93A 1USOA 3HXAA 3JSTA 4C45A 1DCPA 2EBBA 4WILA 4LOWA 2V6UA 1RU0A
chains in the Genus database with same CATH superfamily
4A3EK 4C2MC 1I3QC 1J98A 3TFJA 1SFOA 4A3GK 5IP9C 3HOXC 3S0XA 4A3BK 1JOEA 1EFWA 1SFOK 3GTGA 4A3MK 1VGXA 3TFIA 4X6AK 3G4AA 1Y1WC 3GTGK 2R92A 5HL8A 4OIOA 3M4OC 1TWGA 2YU9A 3PO2C 4Y52K 4OIRA 4YFNA 1O2AA 2EBBA 3FKIC 5C44C 2R92K 1RU0A 4A3LC 3HOZC 1TWGK 5FJ8K 2YU9K 2R7ZA 1I6HC 3S15K 3GTQC 4WILA 2JA7A 4A3IC 2R7ZK 3CQZA 1DCHA 2CW0A 2GSUA 3GTOC 4KMAA 2JA7K 4GTEA 3CQZK 2B63A 5IOTA 2Y3PA 3HOWC 3EQLA 4A93C 1G51A 2B63K 3S2HC 1J6XA 4XLNA 1SMYA 3S17C 3S2DK 1O27A 4A3JK 1B4BA 4KB4A 4LR2A 2XCRB 5C4XC 4J3NA 1JQWA 4GTBA 2Y0SL 4C3JK 4KMDA 2VUMC 1ZVUA 4BBRC 4C3HK 4GTFA 3VA7A 3RZDC 3A8JA 3G4CA 4C3IK 4A3EC 1PJ7A 4YFXA 1WQHA 2NVXA 1V5VA 4A3BC 2W7VA 1EI6A 2NVXK 1HQMA 3H3VL 4OIPA 1YCLA 1DCPA 3GTGC 3A8IA 3GEIA 1TWHA 4Y52C 3LPXA 2R92C 1WOOA 5C3EC 1TWHK 1TWGC 2YU9C 5EGEA 5IOSA 2R7ZC 4GTDA 1L0WA 5IYCK 2JA7C 1VH2A 3CQZC 4A3DK 3MMLB 1XZQB 3GTLC 1INNA 4P9SA 3S16K 3S1QK 2FQTA 3S1RK 3A8KA 3S2DC 2GSOA 1EH1A 1O25A 3L4KA 2WB1D 3HOYC 2E2HA 1TWFA 1O26A 4C3JC 1YX2A 3AD7C 2E2HK 2O5IA 5IP7K 1TWFK 4C3HC 4GFQA 2NVQK 1GE9A 4XCHA 3AQPA 2JA5C 4KM9A 2NVYA 2R93A 1IQ0A 1F93A 4C45A 1X31C 1IBAA 2NVYK 1O24A 4LJZA 2R93K 2E2JK 4RMFA 4KM8A 4MQ9A 1XZPA 5TJ3A 3S14K 4BY1K 4AH6A 3BP3A 1TWHC 3LAJA 2JA8C 3H3VD 5M3MK 3S1NK 5TMCA 3IPJA 4A3CK 3GTPA 3HOUK 1O28A 1PJ5A 5IYBC 3GTPK 3HOVK 3L4JA 4A3DC 1TWAA 4KC6A 2CFAA 4A3FK 3ERED 3RZOC 1TWAK 1WSVA 3N0BA 4YG2A 4KN4A 4QIWD 3S1RC 2P8TA 1YNJA 3GTMA 2WB1L 1XXCA 4GTLA 3S1MC 1UV7A 4ZH4A 3GTMK 4LLGA 5IP7C 1TWFC 1I50C 2NVQC 4BY7C 4QJVA 5M5YK 1AB4A 4KATA 1XXBA 2E2IA 1Y1VA 3N3YA 2V6UA 1BGWA 2NVTK 3K7AK 4Y7NC 4KASA 1Y1VK 2E2IK 2NVYC 1R9TC 1TWCA 4LOWA 3OREA 2R93C 5C4JK 3I4MK 2P5MA 2E2JC 1TWCK 3AD9C 3WODA 4JK1A 3FHZA 4Q5SA 2D6FC 1KQ4A 3S14C 4A3GC 4BY1C 1SFOC 4A3MC 3S1NC 4X6AC 4LK1A 3HOUC 1K83A 3GTPC 3HOVC 1I6VA 3BUEA 3SZZA 1K83K 4A3FC 4OIQA 4BXXK 1TWAC 1EQRA 3S15C 3T01A 4QIWL 3TFHA 4LQYA 5JFEA 4PABA 1WCMA 1WOPA 2XCQA 3GTJA 1WCMK 1I3QA 3GTMC 3AH5A 3GTJK 2B63C 1I3QK 3HOXK 2KWAA 3CAGA 4A3JC 4KMHA 1ZBSA 5L46A 3K7AC 3ADAC 4LK0A 4G7ZA 2WAQD 2A6EA 4MEYA 4BKWA 5C4JC 5E68A 3FKIA 3I4MC 1VJEA 1TWCC 4OINA 1YNNA 3PO2K 3FKIK 4C3IC 4KDDA 1ZYRA 4BLBA 3M3YK 3GTOA 2ZFZA 2NVXC 1B4AA 3AD8C 2A69A 3HKZD 3GTOK 2ZUEA 1BJTA 4BBSK 4WJ3M 3T00A 4O2DA 4A3KK 1J6WA 3HOWK 1XZQA 5FLMK 3S2HK 1HI9A 4BXXC 5IYDK 4Q4ZA 3GTKA 2VUMA 1F9NA 4GTCA 4G7OA 5IYCC 3GTKK 4G0UA 2VUMK 4PAAA 1DCOA 1WCMC 4BBRK 4KAWX 1DD5A 3GTJC 4P5AA 3S16C 3S1QC 1USMA 4P5BA 4KMUA 3GIRA 3GSIA 1XPPA 1IE0A 5TMFA 1IL2A 1VLOA 1F7VA 3HXAA 2WAQL 3JSTA 4ILDA 2E2HC 3AQOA 1BS2A 3I4NK 1JVIA 1WQFA 5C3EK 1J6VA 4AYBD 2FQOA 3M3YC 3NUHA 3GDZA 5M5WK 3BP8C 2PMZD 1ISEA 3HKZL 3GTLA 3QX3A 4BBSC 1O2FB 3DXJA 4A3KC 3GTLK 2PA8D 5EGHA 3SZYA 3PO3K 1WIHA 5FLMC 2XCOA 3GEEA 3T02A 3TTGA 2V6SA 5IYDC 1USOA 4G0VA 1WORA 3HOYK 4KARA 2PPBA 4A3CC 3H0GA 4KB2A 3GTKC 4G0WA 1XXAA 3H0GK 4XSZA 2A68A 4FM9A 2JA5A 2JA6A 3OPFA 4NOIA 2JA5K 2ZUFA 2JA6K 5IORA 1PJ6A 2V6TA 1O29A 3Q3QA 4M1XA 1WSRA 1C0AA 5JVOA 3OEPA 1ZQ1C 1ZXOA 4KN7A 3I4NC 4C2MK 1EK8A 3V4GA 5IP9K 2A6HA 4AYBL 3N0CA 4XSXA 1IW7A 2JA8K 2NVTC 1Y1WA 1BDFA 2E2IC 1Y1VC 3GEHA 4G7HA 2PMZL 1Y1WK 2GSNA 5IYBK 3M4OK 5C44K 1XZPB 5M5XK 2O5JA 4A3LK 1VRQC 2PHCB 3HOZK 3GTQA 3PO3C 2PA8L 4GTAA 3RZOK 4BLAA 2GAHC 4MEXA 2RGRA 1I6HK 4XLPA 4YFKA 3GTQK 2RH6A 4GT9A 4DDQA 5IOQA 4A3IK 2BE5A 1I50A 3S1MK 5M3FK 4WJ4A 2CFAB 3H0GC 4A93K 1I50K 5CJ9A 4FZBA 4BY7K 2GAGC 1K83C 1O2BA 3S17K 2JH3A 3LAPA 1F7UA 2JA6C 4GZYA 1R9TA 1WQGA 2Y0SD 5C4XK 4Y7NK 1R9TK 5CHPA 3FOFA 1IS1A 1WOSA 4QJVB 3FOEA 3RZDK 5D4DA
chains in the Genus database with same CATH topology
1DCOA 1USMA 2V6SA 1DCHA 2V6TA 1F93A 1USOA 3HXAA 3JSTA 4C45A 1DCPA 2EBBA 4WILA 4LOWA 2V6UA 1RU0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DCO A;  1USM A;  2V6S A;  1DCH A;  2V6T A;  1F93 A;  1USO A;  3HXA A;  3JST A;  4C45 A;  1DCP A;  2EBB A;  4WIL A;  4LOW A;  2V6U A;  1RU0 A; 
#chains in the Genus database with same CATH topology
 4A3E K;  4C2M C;  1I3Q C;  1J98 A;  3TFJ A;  1SFO A;  4A3G K;  5IP9 C;  3HOX C;  3S0X A;  4A3B K;  1JOE A;  1EFW A;  1SFO K;  3GTG A;  4A3M K;  1VGX A;  3TFI A;  4X6A K;  3G4A A;  1Y1W C;  3GTG K;  2R92 A;  5HL8 A;  4OIO A;  3M4O C;  1TWG A;  2YU9 A;  3PO2 C;  4Y52 K;  4OIR A;  4YFN A;  1O2A A;  2EBB A;  3FKI C;  5C44 C;  2R92 K;  1RU0 A;  4A3L C;  3HOZ C;  1TWG K;  5FJ8 K;  2YU9 K;  2R7Z A;  1I6H C;  3S15 K;  3GTQ C;  4WIL A;  2JA7 A;  4A3I C;  2R7Z K;  3CQZ A;  1DCH A;  2CW0 A;  2GSU A;  3GTO C;  4KMA A;  2JA7 K;  4GTE A;  3CQZ K;  2B63 A;  5IOT A;  2Y3P A;  3HOW C;  3EQL A;  4A93 C;  1G51 A;  2B63 K;  3S2H C;  1J6X A;  4XLN A;  1SMY A;  3S17 C;  3S2D K;  1O27 A;  4A3J K;  1B4B A;  4KB4 A;  4LR2 A;  2XCR B;  5C4X C;  4J3N A;  1JQW A;  4GTB A;  2Y0S L;  4C3J K;  4KMD A;  2VUM C;  1ZVU A;  4BBR C;  4C3H K;  4GTF A;  3VA7 A;  3RZD C;  3A8J A;  3G4C A;  4C3I K;  4A3E C;  1PJ7 A;  4YFX A;  1WQH A;  2NVX A;  1V5V A;  4A3B C;  2W7V A;  1EI6 A;  2NVX K;  1HQM A;  3H3V L;  4OIP A;  1YCL A;  1DCP A;  3GTG C;  3A8I A;  3GEI A;  1TWH A;  4Y52 C;  3LPX A;  2R92 C;  1WOO A;  5C3E C;  1TWH K;  1TWG C;  2YU9 C;  5EGE A;  5IOS A;  2R7Z C;  4GTD A;  1L0W A;  5IYC K;  2JA7 C;  1VH2 A;  3CQZ C;  4A3D K;  3MML B;  1XZQ B;  3GTL C;  1INN A;  4P9S A;  3S16 K;  3S1Q K;  2FQT A;  3S1R K;  3A8K A;  3S2D C;  2GSO A;  1EH1 A;  1O25 A;  3L4K A;  2WB1 D;  3HOY C;  2E2H A;  1TWF A;  1O26 A;  4C3J C;  1YX2 A;  3AD7 C;  2E2H K;  2O5I A;  5IP7 K;  1TWF K;  4C3H C;  4GFQ A;  2NVQ K;  1GE9 A;  4XCH A;  3AQP A;  2JA5 C;  4KM9 A;  2NVY A;  2R93 A;  1IQ0 A;  1F93 A;  4C45 A;  1X31 C;  1IBA A;  2NVY K;  1O24 A;  4LJZ A;  2R93 K;  2E2J K;  4RMF A;  4KM8 A;  4MQ9 A;  1XZP A;  5TJ3 A;  3S14 K;  4BY1 K;  4AH6 A;  3BP3 A;  1TWH C;  3LAJ A;  2JA8 C;  3H3V D;  5M3M K;  3S1N K;  5TMC A;  3IPJ A;  4A3C K;  3GTP A;  3HOU K;  1O28 A;  1PJ5 A;  5IYB C;  3GTP K;  3HOV K;  3L4J A;  4A3D C;  1TWA A;  4KC6 A;  2CFA A;  4A3F K;  3ERE D;  3RZO C;  1TWA K;  1WSV A;  3N0B A;  4YG2 A;  4KN4 A;  4QIW D;  3S1R C;  2P8T A;  1YNJ A;  3GTM A;  2WB1 L;  1XXC A;  4GTL A;  3S1M C;  1UV7 A;  4ZH4 A;  3GTM K;  4LLG A;  5IP7 C;  1TWF C;  1I50 C;  2NVQ C;  4BY7 C;  4QJV A;  5M5Y K;  1AB4 A;  4KAT A;  1XXB A;  2E2I A;  1Y1V A;  3N3Y A;  2V6U A;  1BGW A;  2NVT K;  3K7A K;  4Y7N C;  4KAS A;  1Y1V K;  2E2I K;  2NVY C;  1R9T C;  1TWC A;  4LOW A;  3ORE A;  2R93 C;  5C4J K;  3I4M K;  2P5M A;  2E2J C;  1TWC K;  3AD9 C;  3WOD A;  4JK1 A;  3FHZ A;  4Q5S A;  2D6F C;  1KQ4 A;  3S14 C;  4A3G C;  4BY1 C;  1SFO C;  4A3M C;  3S1N C;  4X6A C;  4LK1 A;  3HOU C;  1K83 A;  3GTP C;  3HOV C;  1I6V A;  3BUE A;  3SZZ A;  1K83 K;  4A3F C;  4OIQ A;  4BXX K;  1TWA C;  1EQR A;  3S15 C;  3T01 A;  4QIW L;  3TFH A;  4LQY A;  5JFE A;  4PAB A;  1WCM A;  1WOP A;  2XCQ A;  3GTJ A;  1WCM K;  1I3Q A;  3GTM C;  3AH5 A;  3GTJ K;  2B63 C;  1I3Q K;  3HOX K;  2KWA A;  3CAG A;  4A3J C;  4KMH A;  1ZBS A;  5L46 A;  3K7A C;  3ADA C;  4LK0 A;  4G7Z A;  2WAQ D;  2A6E A;  4MEY A;  4BKW A;  5C4J C;  5E68 A;  3FKI A;  3I4M C;  1VJE A;  1TWC C;  4OIN A;  1YNN A;  3PO2 K;  3FKI K;  4C3I C;  4KDD A;  1ZYR A;  4BLB A;  3M3Y K;  3GTO A;  2ZFZ A;  2NVX C;  1B4A A;  3AD8 C;  2A69 A;  3HKZ D;  3GTO K;  2ZUE A;  1BJT A;  4BBS K;  4WJ3 M;  3T00 A;  4O2D A;  4A3K K;  1J6W A;  3HOW K;  1XZQ A;  5FLM K;  3S2H K;  1HI9 A;  4BXX C;  5IYD K;  4Q4Z A;  3GTK A;  2VUM A;  1F9N A;  4GTC A;  4G7O A;  5IYC C;  3GTK K;  4G0U A;  2VUM K;  4PAA A;  1DCO A;  1WCM C;  4BBR K;  4KAW X;  1DD5 A;  3GTJ C;  4P5A A;  3S16 C;  3S1Q C;  1USM A;  4P5B A;  4KMU A;  3GIR A;  3GSI A;  1XPP A;  1IE0 A;  5TMF A;  1IL2 A;  1VLO A;  1F7V A;  3HXA A;  2WAQ L;  3JST A;  4ILD A;  2E2H C;  3AQO A;  1BS2 A;  3I4N K;  1JVI A;  1WQF A;  5C3E K;  1J6V A;  4AYB D;  2FQO A;  3M3Y C;  3NUH A;  3GDZ A;  5M5W K;  3BP8 C;  2PMZ D;  1ISE A;  3HKZ L;  3GTL A;  3QX3 A;  4BBS C;  1O2F B;  3DXJ A;  4A3K C;  3GTL K;  2PA8 D;  5EGH A;  3SZY A;  3PO3 K;  1WIH A;  5FLM C;  2XCO A;  3GEE A;  3T02 A;  3TTG A;  2V6S A;  5IYD C;  1USO A;  4G0V A;  1WOR A;  3HOY K;  4KAR A;  2PPB A;  4A3C C;  3H0G A;  4KB2 A;  3GTK C;  4G0W A;  1XXA A;  3H0G K;  4XSZ A;  2A68 A;  4FM9 A;  2JA5 A;  2JA6 A;  3OPF A;  4NOI A;  2JA5 K;  2ZUF A;  2JA6 K;  5IOR A;  1PJ6 A;  2V6T A;  1O29 A;  3Q3Q A;  4M1X A;  1WSR A;  1C0A A;  5JVO A;  3OEP A;  1ZQ1 C;  1ZXO A;  4KN7 A;  3I4N C;  4C2M K;  1EK8 A;  3V4G A;  5IP9 K;  2A6H A;  4AYB L;  3N0C A;  4XSX A;  1IW7 A;  2JA8 K;  2NVT C;  1Y1W A;  1BDF A;  2E2I C;  1Y1V C;  3GEH A;  4G7H A;  2PMZ L;  1Y1W K;  2GSN A;  5IYB K;  3M4O K;  5C44 K;  1XZP B;  5M5X K;  2O5J A;  4A3L K;  1VRQ C;  2PHC B;  3HOZ K;  3GTQ A;  3PO3 C;  2PA8 L;  4GTA A;  3RZO K;  4BLA A;  2GAH C;  4MEX A;  2RGR A;  1I6H K;  4XLP A;  4YFK A;  3GTQ K;  2RH6 A;  4GT9 A;  4DDQ A;  5IOQ A;  4A3I K;  2BE5 A;  1I50 A;  3S1M K;  5M3F K;  4WJ4 A;  2CFA B;  3H0G C;  4A93 K;  1I50 K;  5CJ9 A;  4FZB A;  4BY7 K;  2GAG C;  1K83 C;  1O2B A;  3S17 K;  2JH3 A;  3LAP A;  1F7U A;  2JA6 C;  4GZY A;  1R9T A;  1WQG A;  2Y0S D;  5C4X K;  4Y7N K;  1R9T K;  5CHP A;  3FOF A;  1IS1 A;  1WOS A;  4QJV B;  3FOE A;  3RZD K;  5D4D A; 
#chains in the Genus database with same CATH homology
 1DCO A;  1USM A;  2V6S A;  1DCH A;  2V6T A;  1F93 A;  1USO A;  3HXA A;  3JST A;  4C45 A;  1DCP A;  2EBB A;  4WIL A;  4LOW A;  2V6U A;  1RU0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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