3BY4A

Structure of ovarian tumor (otu) domain in complex with ubiquitin
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
172
structure length
172
Chain Sequence
RVLKSTEMSIGGSGENVLSVHPVLDDNSCLFHAIAYGIFKQDSVRDLREMVSKEVLNNPVKFNDAILDKPNKDYAQWILKMESWGGAIEIGIISDALAVAIYVVDIDAVKIEKFNEDKFDNYILILFNGIHYDSLTMNEFKTVFNKNQPESDDVLTAALQLASNLKQTGYSF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for ubiquitin recognition by the Otu1 ovarian tumor domain protein
pubmed doi rcsb
molecule tags Cell cycle, hydrolase
source organism Saccharomyces cerevisiae
molecule keywords Ubiquitin thioesterase OTU1
total genus 48
structure length 172
sequence length 172
ec nomenclature ec 3.4.19.12: Ubiquitinyl hydrolase 1.
pdb deposition date 2008-01-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02338 OTU OTU-like cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.80 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cathepsin B; Chain A 3by4A00
4BOQA 4HXDB 4BOZA 3PHXA 5JZEA 3PRMA 3PSEA 3PT2A 4BOPA 3C0RA 3PHWA 3PRPA 3ZNHA 3PHUA 4BOSA 4BOUA 3TMPA 3BY4A
chains in the Genus database with same CATH superfamily
3MHSA 3IUTA 2JQFR 4W4UA 1PBHA 1CQDA 2XU4A 1U9WA 3QT4A 3HHAA 1HUCB 3WXEA 4BQVA 5EGWA 1YK8A 4BOZA 1BP4A 2B1NA 2R9FA 5CHVA 1ITOA 4ZUXU 1ZCMA 4QRVA 5JZEA 3QJ3A 4MSXA 2OP3A 4W5CA 4X6JA 2G6DA 3HWNA 1NL6A 3O65A 3GCBA 3AI8A 4OW0A 1GCBA 3PHUA 4Q8GA 2E00A 1AU3A 3BOWA 3PRPA 3OVXA 3BBAA 8PCHA 3F75A 5JA7A 3PT2A 1TL9A 2JTCA 5J94A 2NQGA 1ZIVA 2DC9A 1NQCA 1AU0A 4PT5A 4Q8HA 4PP2E 5KO3A 1ICFA 3K24A 2OZ2A 3KWZA 2NQIA 1FH0A 2DCDA 4YV8A 1MEMA 4BOPA 2FUDA 2FTDA 1F29A 1U9QX 4M0WA 2GHUA 3B21A 3H89A 4MZSA 2GFOA 4HWYA 3BB7A 3B79A 2AIMA 1AU2A 4P6EA 2C0YA 2DOSA 1UKFA 2BDZA 2PREA 4FIPA 3OF9A 1PCIA 4QH6A 4YYVA 4MI7A 3I06A 2PNSA 3MP2A 2AYNA 3PSEA 4YYUA 4RF0A 1ME3A 4DMXA 3KFQA 1NB5A 2OULA 3P5VA 1Y08A 2BU3A 4A5UA 1VSNA 1U9VA 2G8EA 1MS6A 3TRKA 3D6SA 1YVBA 1VJVA 1IWDA 2Y6EA 3E9SA 4I05A 5PADA 4X6HA 4YYRA 1YT7A 1BGOA 4OEMA 2FQ9A 2PADA 1X9YA 1S4VA 3PBHA 1F2AA 4PP1A 2FT2A 3P5UA 2DC6A 3O0UA 1ME4A 3I3TA 3PDFA 3S3RA 2B1MA 1EWPA 2FYEA 1BY8A 1EWMA 2FRAA 1STFE 3PW3A 4N79A 1AU4A 4FJCA 2HHNA 2IBIA 1QOLA 1PE6A 1PVJA 2DJFB 1JQPA 1SNKA 1GLOA 3BCNA 3PNRA 3IV2A 1TLOA 2E01A 2YJ2A 2AGAA 2PBHA 3WXFA 4YYQA 1QMYA 1POPA 3H8BA 3HD3A 3CBKA 1ATKA 4WURA 1PPPA 4CDCB 2AUZA 3PHWA 2YJBA 4YVAA 4QRXA 3RVXA 4N8WA 2E03A 4G54A 3P5XA 4BPVA 2CIOA 1MHWA 3N4CA 2JRIA 1KHPA 1CV8A 1CPJA 2VHSA 3C9EA 3KKUA 3USVA 1DF0A 2FRQA 1EWLA 1THEA 3PRMA 1PIPA 3K8UA 2R9MA 3RNVA 3KW9A 1U5IA 3ZUAA 4PI3A 4WA6A 4XZXA 1U9XA 2E02A 4RNAA 3TNXA 4CDDB 3MHHA 2O6XA 4OVZB 1O0EA 3BPFA 4CZWA 2DCAA 3K9MA 4XUIA 3W30A 2H7JA 2FO5A 4YYWA 2XU1A 4BOUA 1PADA 1TU6A 1KFUL 3U8EA 1K3BB 5CVNB 9PAPA 2NQAA 3RVWA 3MTNA 3NHEA 3RVVA 4BOQA 2G7YA 2WBFX 1GMYA 5F02A 1QXPA 3V6EA 2P0RA 1GECE 1AYVA 2AYOA 1KXRA 1KFXL 1F2BA 2XU5A 4CDFB 3V6CA 4D8BA 2UZJA 3M99A 2Z84A 2F1GA 3P5WA 3PHXA 5CVOB 1PXVA 1NLJA 3C0RA 2R9NA 2P86A 5A24A 5CVMA 3IFUA 1YALA 2J7QA 1PPNA 2DZYA 4HXDB 2AUXA 3CH3X 2HD5A 2DJGB 3IMAA 4BS6A 3H6SA 2AVWA 2R9CA 3KWBX 3LFYA 2AS8A 2BTWB 4K7CA 4XR7A 3IHPA 4AXLA 2ARYA 1AYUA 2Y5BA 4AXMA 2HWKA 3CH2X 4KLBA 4IP3A 4W5BA 1CS8A 2HH5A 2J7QC 4BS5A 1AYWA 2YJ9A 4RF1A 4R3DA 4I04A 1XKGA 1CSBB 3TMPA 2ATOA 3BY4A 3BWKA 1PPDA 3ZNHA 1EWOA 4OVZA 1YK7A 3MTVA 1KHQA 2R6NA 1MDWA 1CB5A 4QRGA 3OQCA 2DC8A 3DF0A 7PCKA 4FK5A 1MIRA 3QSDA 4N4ZA 3LXSA 1MEGA 1EF7A 3IEJA 3F5VA 3MJ5A 2AU1A 5EZQA 3E1ZB 4OELA 4BSQA 1Q6KA 4RKXA 1SP4B 4IUMA 1CJLA 5JH3A 1A6RA 3WXGA 2NQDB 3BPMA 6PADA 5K16A 2DCCA 1DEUA 4P6GA 1NB3A 4MZOA 3IOQA 3KX1A 2G8JA 1BQIA 3O1GA 2YJ8A 3CBJA 1PPOA 1AECA 1DKIA 4D8IA 2XU3A 1CTEA 4MM3B 2DCBA 5EF4A 4D8EA 3BC3A 1M6DA 2FE8A 4P16A 2IPPB 3W31A 3OISA 2P7UA 4RY2A 5FPWA 3N3KA 4REZA 1NPZA 2BDLA 5EZSA 1QDQA 4GUAA 4CDEB 2R9OA 3N3GA 3OVZA 4DMYA 1Y4HA 3MORA 1F2CA 4X6IA 5E6JA 2F7DA 2BTWA 3OF8A 2DC7A 4I07A 3H7DA 4ZTBA 2CB5A 4QBBA 4PADA 1YZBA 2DZZA 2JQGR 4YYSA 1CVZA 3KSEA 5CHTA 3HHIA 3ERVA 4BOSA 2VHFA 3S3QA 2HXZA 1AIMA 2ACTA 2YJCA 3H8CA
chains in the Genus database with same CATH topology
4A5UA 4OVZA 3MTVA 3TRKA 3OQCA 3W30A 4BOUA 4BOZA 3E9SA 3MJ5A 5EZQA 4RKXA 5JZEA 4IUMA 3O65A 4BOQA 4OW0A 3PHUA 3PRPA 1DKIA 4D8IA 3BBAA 4MM3B 4D8EA 3PT2A 2FE8A 1PVJA 4D8BA 4P16A 2UZJA 2JTCA 2Z84A 3W31A 3PHXA 3C0RA 4PT5A 4REZA 3IFUA 2AGAA 2J7QA 5EZSA 5KO3A 4GUAA 4WURA 4HXDB 4BOPA 3PHWA 2BTWB 4M0WA 3B21A 5E6JA 2BTWA 3BB7A 2HWKA 4ZTBA 2JRIA 2DOSA 4IP3A 1YZBA 2J7QC 1UKFA 3PRMA 4RF1A 4MI7A 4R3DA 3RNVA 3MP2A 3PSEA 4XZXA 4BOSA 4RF0A 3TMPA 3BY4A 4RNAA 3ZNHA 4OVZB 2BU3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BOQ A;  4HXD B;  4BOZ A;  3PHX A;  5JZE A;  3PRM A;  3PSE A;  3PT2 A;  4BOP A;  3C0R A;  3PHW A;  3PRP A;  3ZNH A;  3PHU A;  4BOS A;  4BOU A;  3TMP A;  3BY4 A; 
#chains in the Genus database with same CATH topology
 3MHS A;  3IUT A;  2JQF R;  4W4U A;  1PBH A;  1CQD A;  2XU4 A;  1U9W A;  3QT4 A;  3HHA A;  1HUC B;  3WXE A;  4BQV A;  5EGW A;  1YK8 A;  4BOZ A;  1BP4 A;  2B1N A;  2R9F A;  5CHV A;  1ITO A;  4ZUX U;  1ZCM A;  4QRV A;  5JZE A;  3QJ3 A;  4MSX A;  2OP3 A;  4W5C A;  4X6J A;  2G6D A;  3HWN A;  1NL6 A;  3O65 A;  3GCB A;  3AI8 A;  4OW0 A;  1GCB A;  3PHU A;  4Q8G A;  2E00 A;  1AU3 A;  3BOW A;  3PRP A;  3OVX A;  3BBA A;  8PCH A;  3F75 A;  5JA7 A;  3PT2 A;  1TL9 A;  2JTC A;  5J94 A;  2NQG A;  1ZIV A;  2DC9 A;  1NQC A;  1AU0 A;  4PT5 A;  4Q8H A;  4PP2 E;  5KO3 A;  1ICF A;  3K24 A;  2OZ2 A;  3KWZ A;  2NQI A;  1FH0 A;  2DCD A;  4YV8 A;  1MEM A;  4BOP A;  2FUD A;  2FTD A;  1F29 A;  1U9Q X;  4M0W A;  2GHU A;  3B21 A;  3H89 A;  4MZS A;  2GFO A;  4HWY A;  3BB7 A;  3B79 A;  2AIM A;  1AU2 A;  4P6E A;  2C0Y A;  2DOS A;  1UKF A;  2BDZ A;  2PRE A;  4FIP A;  3OF9 A;  1PCI A;  4QH6 A;  4YYV A;  4MI7 A;  3I06 A;  2PNS A;  3MP2 A;  2AYN A;  3PSE A;  4YYU A;  4RF0 A;  1ME3 A;  4DMX A;  3KFQ A;  1NB5 A;  2OUL A;  3P5V A;  1Y08 A;  2BU3 A;  4A5U A;  1VSN A;  1U9V A;  2G8E A;  1MS6 A;  3TRK A;  3D6S A;  1YVB A;  1VJV A;  1IWD A;  2Y6E A;  3E9S A;  4I05 A;  5PAD A;  4X6H A;  4YYR A;  1YT7 A;  1BGO A;  4OEM A;  2FQ9 A;  2PAD A;  1X9Y A;  1S4V A;  3PBH A;  1F2A A;  4PP1 A;  2FT2 A;  3P5U A;  2DC6 A;  3O0U A;  1ME4 A;  3I3T A;  3PDF A;  3S3R A;  2B1M A;  1EWP A;  2FYE A;  1BY8 A;  1EWM A;  2FRA A;  1STF E;  3PW3 A;  4N79 A;  1AU4 A;  4FJC A;  2HHN A;  2IBI A;  1QOL A;  1PE6 A;  1PVJ A;  2DJF B;  1JQP A;  1SNK A;  1GLO A;  3BCN A;  3PNR A;  3IV2 A;  1TLO A;  2E01 A;  2YJ2 A;  2AGA A;  2PBH A;  3WXF A;  4YYQ A;  1QMY A;  1POP A;  3H8B A;  3HD3 A;  3CBK A;  1ATK A;  4WUR A;  1PPP A;  4CDC B;  2AUZ A;  3PHW A;  2YJB A;  4YVA A;  4QRX A;  3RVX A;  4N8W A;  2E03 A;  4G54 A;  3P5X A;  4BPV A;  2CIO A;  1MHW A;  3N4C A;  2JRI A;  1KHP A;  1CV8 A;  1CPJ A;  2VHS A;  3C9E A;  3KKU A;  3USV A;  1DF0 A;  2FRQ A;  1EWL A;  1THE A;  3PRM A;  1PIP A;  3K8U A;  2R9M A;  3RNV A;  3KW9 A;  1U5I A;  3ZUA A;  4PI3 A;  4WA6 A;  4XZX A;  1U9X A;  2E02 A;  4RNA A;  3TNX A;  4CDD B;  3MHH A;  2O6X A;  4OVZ B;  1O0E A;  3BPF A;  4CZW A;  2DCA A;  3K9M A;  4XUI A;  3W30 A;  2H7J A;  2FO5 A;  4YYW A;  2XU1 A;  4BOU A;  1PAD A;  1TU6 A;  1KFU L;  3U8E A;  1K3B B;  5CVN B;  9PAP A;  2NQA A;  3RVW A;  3MTN A;  3NHE A;  3RVV A;  4BOQ A;  2G7Y A;  2WBF X;  1GMY A;  5F02 A;  1QXP A;  3V6E A;  2P0R A;  1GEC E;  1AYV A;  2AYO A;  1KXR A;  1KFX L;  1F2B A;  2XU5 A;  4CDF B;  3V6C A;  4D8B A;  2UZJ A;  3M99 A;  2Z84 A;  2F1G A;  3P5W A;  3PHX A;  5CVO B;  1PXV A;  1NLJ A;  3C0R A;  2R9N A;  2P86 A;  5A24 A;  5CVM A;  3IFU A;  1YAL A;  2J7Q A;  1PPN A;  2DZY A;  4HXD B;  2AUX A;  3CH3 X;  2HD5 A;  2DJG B;  3IMA A;  4BS6 A;  3H6S A;  2AVW A;  2R9C A;  3KWB X;  3LFY A;  2AS8 A;  2BTW B;  4K7C A;  4XR7 A;  3IHP A;  4AXL A;  2ARY A;  1AYU A;  2Y5B A;  4AXM A;  2HWK A;  3CH2 X;  4KLB A;  4IP3 A;  4W5B A;  1CS8 A;  2HH5 A;  2J7Q C;  4BS5 A;  1AYW A;  2YJ9 A;  4RF1 A;  4R3D A;  4I04 A;  1XKG A;  1CSB B;  3TMP A;  2ATO A;  3BY4 A;  3BWK A;  1PPD A;  3ZNH A;  1EWO A;  4OVZ A;  1YK7 A;  3MTV A;  1KHQ A;  2R6N A;  1MDW A;  1CB5 A;  4QRG A;  3OQC A;  2DC8 A;  3DF0 A;  7PCK A;  4FK5 A;  1MIR A;  3QSD A;  4N4Z A;  3LXS A;  1MEG A;  1EF7 A;  3IEJ A;  3F5V A;  3MJ5 A;  2AU1 A;  5EZQ A;  3E1Z B;  4OEL A;  4BSQ A;  1Q6K A;  4RKX A;  1SP4 B;  4IUM A;  1CJL A;  5JH3 A;  1A6R A;  3WXG A;  2NQD B;  3BPM A;  6PAD A;  5K16 A;  2DCC A;  1DEU A;  4P6G A;  1NB3 A;  4MZO A;  3IOQ A;  3KX1 A;  2G8J A;  1BQI A;  3O1G A;  2YJ8 A;  3CBJ A;  1PPO A;  1AEC A;  1DKI A;  4D8I A;  2XU3 A;  1CTE A;  4MM3 B;  2DCB A;  5EF4 A;  4D8E A;  3BC3 A;  1M6D A;  2FE8 A;  4P16 A;  2IPP B;  3W31 A;  3OIS A;  2P7U A;  4RY2 A;  5FPW A;  3N3K A;  4REZ A;  1NPZ A;  2BDL A;  5EZS A;  1QDQ A;  4GUA A;  4CDE B;  2R9O A;  3N3G A;  3OVZ A;  4DMY A;  1Y4H A;  3MOR A;  1F2C A;  4X6I A;  5E6J A;  2F7D A;  2BTW A;  3OF8 A;  2DC7 A;  4I07 A;  3H7D A;  4ZTB A;  2CB5 A;  4QBB A;  4PAD A;  1YZB A;  2DZZ A;  2JQG R;  4YYS A;  1CVZ A;  3KSE A;  5CHT A;  3HHI A;  3ERV A;  4BOS A;  2VHF A;  3S3Q A;  2HXZ A;  1AIM A;  2ACT A;  2YJC A;  3H8C A; 
#chains in the Genus database with same CATH homology
 4A5U A;  4OVZ A;  3MTV A;  3TRK A;  3OQC A;  3W30 A;  4BOU A;  4BOZ A;  3E9S A;  3MJ5 A;  5EZQ A;  4RKX A;  5JZE A;  4IUM A;  3O65 A;  4BOQ A;  4OW0 A;  3PHU A;  3PRP A;  1DKI A;  4D8I A;  3BBA A;  4MM3 B;  4D8E A;  3PT2 A;  2FE8 A;  1PVJ A;  4D8B A;  4P16 A;  2UZJ A;  2JTC A;  2Z84 A;  3W31 A;  3PHX A;  3C0R A;  4PT5 A;  4REZ A;  3IFU A;  2AGA A;  2J7Q A;  5EZS A;  5KO3 A;  4GUA A;  4WUR A;  4HXD B;  4BOP A;  3PHW A;  2BTW B;  4M0W A;  3B21 A;  5E6J A;  2BTW A;  3BB7 A;  2HWK A;  4ZTB A;  2JRI A;  2DOS A;  4IP3 A;  1YZB A;  2J7Q C;  1UKF A;  3PRM A;  4RF1 A;  4MI7 A;  4R3D A;  3RNV A;  3MP2 A;  3PSE A;  4XZX A;  4BOS A;  4RF0 A;  3TMP A;  3BY4 A;  4RNA A;  3ZNH A;  4OVZ B;  2BU3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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