2FO5A

Crystal structure of recombinant barley cysteine endoprotease b isoform 2 (ep-b2) in complex with leupeptin
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
224
structure length
224
Chain Sequence
DLPPSVDWRQKGAVTGVKDQGKCGSCWAFSTVVSVEGINAIRTGSLVSLSEQELIDCDTADNDGCQGGLMDNAFEYIKNNGGLITEAAYPYRAARGTCNVARAAQNSPVVVHIDGHQDVPANSEEDLARAVANQPVSVAVEASGKAFMFYSEGVFTGECGTELDHGVAVVGYGVAEDGKAYWTVKNSWGPSWGEQGYIRVEKDSGASGGLCGIAMEASYPVKTY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Heterologous Expression, Purification, Refolding, and Structural-Functional Characterization of EP-B2, a Self-Activating Barley Cysteine Endoprotease.
pubmed doi rcsb
molecule keywords Cysteine proteinase EP-B 2
molecule tags Hydrolase/hydrolase inhibitor
source organism Hordeum vulgare
total genus 58
structure length 224
sequence length 224
chains with identical sequence B, C, D
ec nomenclature ec 3.4.22.-:
pdb deposition date 2006-01-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2fo5A00
1CSBB 4YYWA 1TLOA 3F5VA 3IV2A 3RVWA 3IHPA 3WXFA 2B1MA 1KXRA 1S4VA 1NB3A 1ME3A 2Y5BA 2JQGR 4CDDB 3KW9A 4X6IA 4CDCB 4WA6A 3KWZA 2F1GA 3KSEA 4MZSA 3MHHA 2YJBA 1CJLA 1EWOA 2F7DA 3BCNA 1CB5A 1BGOA 2HH5A 1YT7A 1O0EA 3IEJA 3D6SA 4FJCA 4PP1A 1ZCMA 3WXEA 2CIOA 4QRXA 4KLBA 1EF7A 2DZYA 3H8BA 3TNXA 3OISA 1AECA 2XU4A 3P5WA 2FRQA 3WXGA 1ITOA 1M6DA 2OULA 3BC3A 3KWBX 3MHSA 4BSQA 2YJ8A 2GFOA 1EWMA 1U9XA 4Q8HA 4N8WA 3DF0A 3N4CA 1KFXL 1Y08A 2E00A 1MHWA 3O1GA 3PBHA 4QRVA 4YYVA 3M99A 4XUIA 2R6NA 1K3BB 1AU0A 2ATOA 2DJGB 3P5VA 2E02A 1NQCA 1NPZA 6PADA 1EWLA 1A6RA 2NQGA 4XR7A 2BDZA 2YJCA 3CBKA 2AUXA 2IPPB 3CH3X 2OZ2A 2E03A 2DCBA 1CV8A 4DMYA 3HD3A 1CPJA 2FT2A 1POPA 3ZUAA 4YVAA 4YV8A 4FIPA 4YYUA 1YVBA 3N3KA 3B79A 2DCAA 3KKUA 2HXZA 1SP4B 3MORA 1BY8A 1CTEA 3MTNA 4CZWA 2DC8A 4PP2E 2FQ9A 2R9MA 4PI3A 5EGWA 1F2BA 4MSXA 2E01A 3HHIA 1F2AA 3QJ3A 1CVZA 1MDWA 1PIPA 1ME4A 2ACTA 3BWKA 2NQIA 3OF8A 5A24A 4I05A 1U9WA 2YJ9A 1U5IA 3IOQA 4X6JA 3IUTA 1BP4A 4YYRA 2AU1A 4MZOA 3RVXA 3AI8A 1TU6A 4I04A 3V6EA 3O0UA 4BQVA 2DC7A 4QH6A 2CB5A 1AU4A 2NQAA 4PADA 2FUDA 2G7YA 1YALA 4FK5A 1NB5A 4CDEB 2P86A 1MEMA 3CBJA 4K7CA 1DEUA 2FTDA 3HHAA 3LXSA 2VHSA 2YJ2A 4YYQA 3F75A 5PADA 5JA7A 1KHPA 4AXLA 1CQDA 4W4UA 1GECE 3S3RA 1KHQA 4ZUXU 3H8CA 1Q6KA 3USVA 4CDFB 3V6CA 4RY2A 1MEGA 2XU5A 3H89A 1QMYA 4X6HA 2Y6EA 5F02A 2R9NA 1X9YA 3I3TA 3HWNA 3C9EA 2AIMA 1CS8A 2DC9A 4OEMA 4QRGA 4Q8GA 2FO5A 5CVMA 1HUCB 5CHTA 2B1NA 2PNSA 2PADA 2ARYA 1ICFA 2PBHA 1PE6A 2AYNA 4BPVA 2G8EA 1QDQA 2VHFA 2DCDA 1NL6A 3H6SA 2P0RA 3K9MA 4I07A 3S3QA 2AYOA 2G6DA 1U9QX 3OVZA 2HHNA 2G8JA 2R9FA 4N4ZA 4OELA 1AIMA 3GCBA 3P5XA 3OF9A 4HWYA 1IWDA 1F2CA 1QXPA 2WBFX 5CHVA 5CVNB 3K24A 4AXMA 1PPPA 3PNRA 2DC6A 4QBBA 5CVOB 4W5BA 1F29A 2GHUA 1EWPA 1AYUA 2C0YA 3BOWA 1VJVA 2XU1A 5FPWA 1PPNA 4DMXA 5EF4A 2R9CA 3KX1A 3LFYA 1XKGA 1BQIA 3CH2X 3NHEA 4W5CA 1SNKA 1YK7A 1PCIA 3IMAA 3PW3A 3U8EA 1PBHA 2JQFR 2O6XA 2XU3A 2AS8A 1KFUL 1U9VA 2DCCA 2BDLA 2PREA 1STFE 1PXVA 1VSNA 1JQPA 1PPOA 5JH3A 7PCKA 3BPMA 4BS5A 3RVVA 3QSDA 2FRAA 1DF0A 3E1ZB 3P5UA 4BS6A 5K16A 1AYWA 1Y4HA 3OVXA 1FH0A 1ZIVA 2IBIA 1GMYA 2FYEA 1YK8A 3I06A 4G54A 1TL9A 1AU2A 8PCHA 4N79A 3H7DA 3N3GA 3K8UA 9PAPA 3QT4A 2AUZA 1MS6A 2DZZA 2DJFB 3KFQA 3PDFA 1NLJA 1AU3A 2AVWA 1GCBA 2HD5A 4YYSA 2OP3A 1MIRA 5J94A 1QOLA 1ATKA 4P6EA 2H7JA 4P6GA 1GLOA 3BPFA 1PPDA 2NQDB 1PADA 1THEA 3ERVA 1AYVA 2R9OA 2P7UA
chains in the Genus database with same CATH superfamily
1CSBB 4YYWA 3W31A 1TLOA 3F5VA 3RNVA 3IV2A 3RVWA 3IHPA 3WXFA 2B1MA 1KXRA 1S4VA 1NB3A 1ME3A 2Y5BA 2JQGR 3MP2A 4CDDB 3KW9A 4X6IA 4CDCB 4WA6A 3KWZA 4OVZB 2F1GA 3KSEA 4MZSA 3MHHA 2YJBA 4HXDB 1CJLA 1EWOA 2F7DA 4M0WA 3BCNA 1CB5A 1BGOA 2HH5A 1YT7A 1O0EA 3IEJA 3D6SA 3W30A 4FJCA 4PP1A 1ZCMA 3PT2A 3WXEA 4R3DA 4WURA 4PT5A 2CIOA 4QRXA 4KLBA 4MM3B 1EF7A 2DZYA 3H8BA 3TNXA 3OISA 1AECA 2XU4A 3P5WA 4BOPA 2FRQA 3WXGA 4GUAA 4IP3A 1ITOA 3PRPA 1M6DA 2OULA 3BC3A 3KWBX 3MHSA 4BSQA 2YJ8A 2GFOA 1EWMA 1U9XA 5JZEA 4Q8HA 4N8WA 2J7QC 3DF0A 3N4CA 1KFXL 1Y08A 2E00A 1MHWA 3O1GA 3PBHA 4QRVA 4YYVA 3M99A 2BTWA 4XUIA 2R6NA 1K3BB 1AU0A 2ATOA 4REZA 2DJGB 3P5VA 2E02A 4IUMA 1NQCA 1NPZA 6PADA 4ZTBA 1EWLA 1A6RA 2NQGA 4XR7A 2Z84A 2BDZA 4P16A 2YJCA 3CBKA 3O65A 2AUXA 2IPPB 3CH3X 2OZ2A 2E03A 2DOSA 2DCBA 1CV8A 4DMYA 3HD3A 1CPJA 2FT2A 1POPA 3ZUAA 4YVAA 4D8IA 4YV8A 4FIPA 4YYUA 1YVBA 3N3KA 3B79A 2DCAA 3KKUA 5KO3A 2HXZA 1SP4B 3MORA 1BY8A 1CTEA 3MTNA 4CZWA 2DC8A 3E9SA 4PP2E 2FQ9A 3TRKA 2R9MA 4PI3A 5EGWA 1F2BA 4MSXA 2E01A 2FE8A 3HHIA 1F2AA 3QJ3A 1CVZA 1MDWA 1PIPA 1ME4A 2ACTA 3BWKA 2NQIA 3PRMA 3OF8A 5A24A 4I05A 2AGAA 3IFUA 1U9WA 2YJ9A 1U5IA 3IOQA 4X6JA 3IUTA 1BP4A 1YZBA 4YYRA 2AU1A 4MZOA 3RVXA 3AI8A 1TU6A 4MI7A 4I04A 3V6EA 2JTCA 3O0UA 3PHUA 4BQVA 2DC7A 4QH6A 2CB5A 1AU4A 2NQAA 4PADA 2BU3A 2FUDA 2G7YA 1YALA 4FK5A 1NB5A 4CDEB 2P86A 1MEMA 3CBJA 4K7CA 1DEUA 2FTDA 3HHAA 4BOSA 3LXSA 2VHSA 2YJ2A 4YYQA 4RF1A 3F75A 5PADA 4BOUA 5JA7A 1KHPA 4AXLA 1CQDA 4W4UA 1GECE 3S3RA 1KHQA 4ZUXU 3H8CA 1Q6KA 3USVA 4CDFB 3V6CA 4RY2A 1DKIA 3BBAA 1MEGA 2XU5A 3H89A 1QMYA 4X6HA 2Y6EA 5F02A 2JRIA 2R9NA 1X9YA 3I3TA 3HWNA 3C9EA 2AIMA 5EZSA 1CS8A 2DC9A 4OEMA 4QRGA 4Q8GA 2FO5A 5CVMA 1HUCB 5CHTA 2B1NA 2PNSA 2PADA 2ARYA 1ICFA 3OQCA 2PBHA 1PE6A 2AYNA 4BPVA 2G8EA 3PHXA 1QDQA 2VHFA 2DCDA 1NL6A 3H6SA 2P0RA 3K9MA 4I07A 3S3QA 3PHWA 2AYOA 2G6DA 4OVZA 5E6JA 1U9QX 3OVZA 3MJ5A 2HHNA 4RNAA 2G8JA 2UZJA 2R9FA 4N4ZA 4OELA 3BB7A 1AIMA 3GCBA 3B21A 3P5XA 3OF9A 3TMPA 4HWYA 1IWDA 1F2CA 1QXPA 2WBFX 5CHVA 5CVNB 3K24A 4AXMA 1PPPA 3PNRA 2DC6A 4A5UA 4QBBA 5CVOB 3C0RA 4W5BA 1F29A 4RKXA 2GHUA 1EWPA 4BOZA 1AYUA 2C0YA 3BOWA 1VJVA 2XU1A 5FPWA 1PPNA 4DMXA 5EF4A 4BOQA 2R9CA 3KX1A 3LFYA 4D8EA 1XKGA 1BQIA 3CH2X 3NHEA 4W5CA 1SNKA 1YK7A 4RF0A 1PCIA 3IMAA 3PW3A 3BY4A 4XZXA 3U8EA 1PBHA 2JQFR 2O6XA 2XU3A 2AS8A 1KFUL 1U9VA 2DCCA 2BDLA 2PREA 1STFE 1PXVA 1VSNA 1JQPA 1PPOA 5JH3A 7PCKA 3BPMA 4BS5A 3RVVA 3QSDA 2FRAA 1DF0A 1PVJA 3E1ZB 3P5UA 4BS6A 5K16A 1AYWA 1Y4HA 3OVXA 1FH0A 1ZIVA 2IBIA 1GMYA 2FYEA 1YK8A 3I06A 4G54A 1TL9A 1AU2A 8PCHA 4N79A 2J7QA 3H7DA 3N3GA 5EZQA 3K8UA 9PAPA 3QT4A 2AUZA 1MS6A 2DZZA 2DJFB 3KFQA 3PDFA 1NLJA 4OW0A 1AU3A 2AVWA 1GCBA 2HD5A 4YYSA 2OP3A 1MIRA 5J94A 2BTWB 1QOLA 1ATKA 4P6EA 3PSEA 2HWKA 2H7JA 3ZNHA 1UKFA 4P6GA 1GLOA 3BPFA 1PPDA 2NQDB 1PADA 4D8BA 1THEA 3MTVA 3ERVA 1AYVA 2R9OA 2P7UA
chains in the Genus database with same CATH topology
1W6FA 1CSBB 1E2TA 4YYWA 1TLOA 3F5VA 3IV2A 3RVWA 3IHPA 3WXFA 2B1MA 1KXRA 1S4VA 1NB3A 1ME3A 2Y5BA 2JQGR 4CDDB 3KW9A 4X6IA 4CDCB 4WA6A 3KWZA 2F1GA 3KSEA 4MZSA 3MHHA 2YJBA 1CJLA 1EWOA 2F7DA 4GUZA 3BCNA 1CB5A 1BGOA 2HH5A 1YT7A 1O0EA 3IEJA 3D6SA 4FJCA 4PP1A 1ZCMA 1W5RA 3WXEA 2CIOA 4QRXA 4KLBA 1EF7A 2DZYA 3H8BA 3TNXA 3OISA 4C5PA 1AECA 2XU4A 3P5WA 2FRQA 3WXGA 1ITOA 1M6DA 2OULA 3BC3A 3KWBX 3MHSA 4BSQA 2YJ8A 2GFOA 1EWMA 1U9XA 4Q8HA 4N8WA 3DF0A 3N4CA 1KFXL 1Y08A 2E00A 1MHWA 3O1GA 3PBHA 4QRVA 4YYVA 3M99A 4XUIA 2R6NA 1K3BB 1AU0A 2ATOA 2DJGB 3P5VA 2E02A 1NQCA 1NPZA 6PADA 1EWLA 1A6RA 2NQGA 4XR7A 2BDZA 2YJCA 3CBKA 2AUXA 2IPPB 3CH3X 4NV8A 2OZ2A 2E03A 2DCBA 1CV8A 4DMYA 3HD3A 1CPJA 2FT2A 1POPA 3ZUAA 4YVAA 4YV8A 4FIPA 4YYUA 1YVBA 3N3KA 3B79A 2DCAA 3KKUA 2HXZA 1SP4B 3MORA 1BY8A 1CTEA 3MTNA 4CZWA 2DC8A 4BGFA 4PP2E 2FQ9A 2R9MA 4PI3A 5EGWA 1F2BA 4MSXA 2E01A 3HHIA 1F2AA 3QJ3A 1CVZA 1MDWA 1PIPA 1ME4A 2ACTA 3BWKA 2NQIA 3OF8A 5A24A 4I05A 1U9WA 2YJ9A 1U5IA 3IOQA 4X6JA 3IUTA 1BP4A 4YYRA 2AU1A 4MZOA 3RVXA 3AI8A 1TU6A 4I04A 3V6EA 3O0UA 4BQVA 2DC7A 4QH6A 2CB5A 1AU4A 2NQAA 4PADA 2FUDA 2G7YA 1YALA 4FK5A 1NB5A 4CDEB 2P86A 1MEMA 3CBJA 4K7CA 1DEUA 2FTDA 3HHAA 3LXSA 2VHSA 2YJ2A 4YYQA 3F75A 5PADA 5JA7A 1KHPA 4AXLA 1CQDA 4W4UA 1GECE 3S3RA 1KHQA 4ZUXU 3H8CA 1Q6KA 3USVA 4CDFB 3V6CA 4RY2A 1MEGA 2BSZA 2XU5A 3H89A 1QMYA 4X6HA 2Y6EA 5F02A 2R9NA 1X9YA 3I3TA 3HWNA 3C9EA 2AIMA 1W4TA 1CS8A 2DC9A 4OEMA 4QRGA 4Q8GA 2FO5A 5CVMA 1HUCB 5CHTA 2B1NA 2PNSA 2PADA 2ARYA 1ICFA 2PBHA 1PE6A 2AYNA 4BPVA 2G8EA 1QDQA 2VHFA 2DCDA 2VFBA 1NL6A 3H6SA 2P0RA 3K9MA 4I07A 3S3QA 2AYOA 2G6DA 1U9QX 3OVZA 3LTWA 2HHNA 2G8JA 2R9FA 4N4ZA 4OELA 1AIMA 3GCBA 3P5XA 3OF9A 4HWYA 1IWDA 1F2CA 1QXPA 2WBFX 5CHVA 5CVNB 3K24A 4AXMA 1PPPA 3PNRA 2DC6A 4QBBA 5CVOB 4W5BA 1F29A 2GHUA 1EWPA 1AYUA 2C0YA 3BOWA 1VJVA 2XU1A 5FPWA 1PPNA 4DMXA 5EF4A 2R9CA 3KX1A 3LFYA 1XKGA 1BQIA 3CH2X 3NHEA 4W5CA 1SNKA 1YK7A 1PCIA 3IMAA 3PW3A 3U8EA 1PBHA 2JQFR 2O6XA 2XU3A 2AS8A 1KFUL 1U9VA 2DCCA 2BDLA 2PREA 1STFE 2VFCA 1PXVA 1VSNA 1JQPA 4NV7A 1PPOA 5JH3A 7PCKA 3BPMA 4BS5A 3RVVA 3QSDA 2FRAA 1DF0A 3E1ZB 3P5UA 4BS6A 5K16A 1AYWA 1Y4HA 3OVXA 1FH0A 1ZIVA 2IBIA 1GMYA 2FYEA 1YK8A 3I06A 4G54A 1TL9A 1AU2A 4B55A 8PCHA 4N79A 3D9WA 3H7DA 3N3GA 3K8UA 9PAPA 3QT4A 2AUZA 1MS6A 2DZZA 2DJFB 3KFQA 3PDFA 1NLJA 1AU3A 2AVWA 1GCBA 2HD5A 4YYSA 2OP3A 1MIRA 1GX3A 5J94A 1QOLA 1ATKA 4P6EA 2H7JA 4P6GA 1GLOA 3BPFA 1PPDA 2NQDB 1PADA 1THEA 3ERVA 1AYVA 2R9OA 2P7UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1CSB B;  4YYW A;  1TLO A;  3F5V A;  3IV2 A;  3RVW A;  3IHP A;  3WXF A;  2B1M A;  1KXR A;  1S4V A;  1NB3 A;  1ME3 A;  2Y5B A;  2JQG R;  4CDD B;  3KW9 A;  4X6I A;  4CDC B;  4WA6 A;  3KWZ A;  2F1G A;  3KSE A;  4MZS A;  3MHH A;  2YJB A;  1CJL A;  1EWO A;  2F7D A;  3BCN A;  1CB5 A;  1BGO A;  2HH5 A;  1YT7 A;  1O0E A;  3IEJ A;  3D6S A;  4FJC A;  4PP1 A;  1ZCM A;  3WXE A;  2CIO A;  4QRX A;  4KLB A;  1EF7 A;  2DZY A;  3H8B A;  3TNX A;  3OIS A;  1AEC A;  2XU4 A;  3P5W A;  2FRQ A;  3WXG A;  1ITO A;  1M6D A;  2OUL A;  3BC3 A;  3KWB X;  3MHS A;  4BSQ A;  2YJ8 A;  2GFO A;  1EWM A;  1U9X A;  4Q8H A;  4N8W A;  3DF0 A;  3N4C A;  1KFX L;  1Y08 A;  2E00 A;  1MHW A;  3O1G A;  3PBH A;  4QRV A;  4YYV A;  3M99 A;  4XUI A;  2R6N A;  1K3B B;  1AU0 A;  2ATO A;  2DJG B;  3P5V A;  2E02 A;  1NQC A;  1NPZ A;  6PAD A;  1EWL A;  1A6R A;  2NQG A;  4XR7 A;  2BDZ A;  2YJC A;  3CBK A;  2AUX A;  2IPP B;  3CH3 X;  2OZ2 A;  2E03 A;  2DCB A;  1CV8 A;  4DMY A;  3HD3 A;  1CPJ A;  2FT2 A;  1POP A;  3ZUA A;  4YVA A;  4YV8 A;  4FIP A;  4YYU A;  1YVB A;  3N3K A;  3B79 A;  2DCA A;  3KKU A;  2HXZ A;  1SP4 B;  3MOR A;  1BY8 A;  1CTE A;  3MTN A;  4CZW A;  2DC8 A;  4PP2 E;  2FQ9 A;  2R9M A;  4PI3 A;  5EGW A;  1F2B A;  4MSX A;  2E01 A;  3HHI A;  1F2A A;  3QJ3 A;  1CVZ A;  1MDW A;  1PIP A;  1ME4 A;  2ACT A;  3BWK A;  2NQI A;  3OF8 A;  5A24 A;  4I05 A;  1U9W A;  2YJ9 A;  1U5I A;  3IOQ A;  4X6J A;  3IUT A;  1BP4 A;  4YYR A;  2AU1 A;  4MZO A;  3RVX A;  3AI8 A;  1TU6 A;  4I04 A;  3V6E A;  3O0U A;  4BQV A;  2DC7 A;  4QH6 A;  2CB5 A;  1AU4 A;  2NQA A;  4PAD A;  2FUD A;  2G7Y A;  1YAL A;  4FK5 A;  1NB5 A;  4CDE B;  2P86 A;  1MEM A;  3CBJ A;  4K7C A;  1DEU A;  2FTD A;  3HHA A;  3LXS A;  2VHS A;  2YJ2 A;  4YYQ A;  3F75 A;  5PAD A;  5JA7 A;  1KHP A;  4AXL A;  1CQD A;  4W4U A;  1GEC E;  3S3R A;  1KHQ A;  4ZUX U;  3H8C A;  1Q6K A;  3USV A;  4CDF B;  3V6C A;  4RY2 A;  1MEG A;  2XU5 A;  3H89 A;  1QMY A;  4X6H A;  2Y6E A;  5F02 A;  2R9N A;  1X9Y A;  3I3T A;  3HWN A;  3C9E A;  2AIM A;  1CS8 A;  2DC9 A;  4OEM A;  4QRG A;  4Q8G A;  2FO5 A;  5CVM A;  1HUC B;  5CHT A;  2B1N A;  2PNS A;  2PAD A;  2ARY A;  1ICF A;  2PBH A;  1PE6 A;  2AYN A;  4BPV A;  2G8E A;  1QDQ A;  2VHF A;  2DCD A;  1NL6 A;  3H6S A;  2P0R A;  3K9M A;  4I07 A;  3S3Q A;  2AYO A;  2G6D A;  1U9Q X;  3OVZ A;  2HHN A;  2G8J A;  2R9F A;  4N4Z A;  4OEL A;  1AIM A;  3GCB A;  3P5X A;  3OF9 A;  4HWY A;  1IWD A;  1F2C A;  1QXP A;  2WBF X;  5CHV A;  5CVN B;  3K24 A;  4AXM A;  1PPP A;  3PNR A;  2DC6 A;  4QBB A;  5CVO B;  4W5B A;  1F29 A;  2GHU A;  1EWP A;  1AYU A;  2C0Y A;  3BOW A;  1VJV A;  2XU1 A;  5FPW A;  1PPN A;  4DMX A;  5EF4 A;  2R9C A;  3KX1 A;  3LFY A;  1XKG A;  1BQI A;  3CH2 X;  3NHE A;  4W5C A;  1SNK A;  1YK7 A;  1PCI A;  3IMA A;  3PW3 A;  3U8E A;  1PBH A;  2JQF R;  2O6X A;  2XU3 A;  2AS8 A;  1KFU L;  1U9V A;  2DCC A;  2BDL A;  2PRE A;  1STF E;  1PXV A;  1VSN A;  1JQP A;  1PPO A;  5JH3 A;  7PCK A;  3BPM A;  4BS5 A;  3RVV A;  3QSD A;  2FRA A;  1DF0 A;  3E1Z B;  3P5U A;  4BS6 A;  5K16 A;  1AYW A;  1Y4H A;  3OVX A;  1FH0 A;  1ZIV A;  2IBI A;  1GMY A;  2FYE A;  1YK8 A;  3I06 A;  4G54 A;  1TL9 A;  1AU2 A;  8PCH A;  4N79 A;  3H7D A;  3N3G A;  3K8U A;  9PAP A;  3QT4 A;  2AUZ A;  1MS6 A;  2DZZ A;  2DJF B;  3KFQ A;  3PDF A;  1NLJ A;  1AU3 A;  2AVW A;  1GCB A;  2HD5 A;  4YYS A;  2OP3 A;  1MIR A;  5J94 A;  1QOL A;  1ATK A;  4P6E A;  2H7J A;  4P6G A;  1GLO A;  3BPF A;  1PPD A;  2NQD B;  1PAD A;  1THE A;  3ERV A;  1AYV A;  2R9O A;  2P7U A; 
#chains in the Genus database with same CATH topology
 1CSB B;  4YYW A;  3W31 A;  1TLO A;  3F5V A;  3RNV A;  3IV2 A;  3RVW A;  3IHP A;  3WXF A;  2B1M A;  1KXR A;  1S4V A;  1NB3 A;  1ME3 A;  2Y5B A;  2JQG R;  3MP2 A;  4CDD B;  3KW9 A;  4X6I A;  4CDC B;  4WA6 A;  3KWZ A;  4OVZ B;  2F1G A;  3KSE A;  4MZS A;  3MHH A;  2YJB A;  4HXD B;  1CJL A;  1EWO A;  2F7D A;  4M0W A;  3BCN A;  1CB5 A;  1BGO A;  2HH5 A;  1YT7 A;  1O0E A;  3IEJ A;  3D6S A;  3W30 A;  4FJC A;  4PP1 A;  1ZCM A;  3PT2 A;  3WXE A;  4R3D A;  4WUR A;  4PT5 A;  2CIO A;  4QRX A;  4KLB A;  4MM3 B;  1EF7 A;  2DZY A;  3H8B A;  3TNX A;  3OIS A;  1AEC A;  2XU4 A;  3P5W A;  4BOP A;  2FRQ A;  3WXG A;  4GUA A;  4IP3 A;  1ITO A;  3PRP A;  1M6D A;  2OUL A;  3BC3 A;  3KWB X;  3MHS A;  4BSQ A;  2YJ8 A;  2GFO A;  1EWM A;  1U9X A;  5JZE A;  4Q8H A;  4N8W A;  2J7Q C;  3DF0 A;  3N4C A;  1KFX L;  1Y08 A;  2E00 A;  1MHW A;  3O1G A;  3PBH A;  4QRV A;  4YYV A;  3M99 A;  2BTW A;  4XUI A;  2R6N A;  1K3B B;  1AU0 A;  2ATO A;  4REZ A;  2DJG B;  3P5V A;  2E02 A;  4IUM A;  1NQC A;  1NPZ A;  6PAD A;  4ZTB A;  1EWL A;  1A6R A;  2NQG A;  4XR7 A;  2Z84 A;  2BDZ A;  4P16 A;  2YJC A;  3CBK A;  3O65 A;  2AUX A;  2IPP B;  3CH3 X;  2OZ2 A;  2E03 A;  2DOS A;  2DCB A;  1CV8 A;  4DMY A;  3HD3 A;  1CPJ A;  2FT2 A;  1POP A;  3ZUA A;  4YVA A;  4D8I A;  4YV8 A;  4FIP A;  4YYU A;  1YVB A;  3N3K A;  3B79 A;  2DCA A;  3KKU A;  5KO3 A;  2HXZ A;  1SP4 B;  3MOR A;  1BY8 A;  1CTE A;  3MTN A;  4CZW A;  2DC8 A;  3E9S A;  4PP2 E;  2FQ9 A;  3TRK A;  2R9M A;  4PI3 A;  5EGW A;  1F2B A;  4MSX A;  2E01 A;  2FE8 A;  3HHI A;  1F2A A;  3QJ3 A;  1CVZ A;  1MDW A;  1PIP A;  1ME4 A;  2ACT A;  3BWK A;  2NQI A;  3PRM A;  3OF8 A;  5A24 A;  4I05 A;  2AGA A;  3IFU A;  1U9W A;  2YJ9 A;  1U5I A;  3IOQ A;  4X6J A;  3IUT A;  1BP4 A;  1YZB A;  4YYR A;  2AU1 A;  4MZO A;  3RVX A;  3AI8 A;  1TU6 A;  4MI7 A;  4I04 A;  3V6E A;  2JTC A;  3O0U A;  3PHU A;  4BQV A;  2DC7 A;  4QH6 A;  2CB5 A;  1AU4 A;  2NQA A;  4PAD A;  2BU3 A;  2FUD A;  2G7Y A;  1YAL A;  4FK5 A;  1NB5 A;  4CDE B;  2P86 A;  1MEM A;  3CBJ A;  4K7C A;  1DEU A;  2FTD A;  3HHA A;  4BOS A;  3LXS A;  2VHS A;  2YJ2 A;  4YYQ A;  4RF1 A;  3F75 A;  5PAD A;  4BOU A;  5JA7 A;  1KHP A;  4AXL A;  1CQD A;  4W4U A;  1GEC E;  3S3R A;  1KHQ A;  4ZUX U;  3H8C A;  1Q6K A;  3USV A;  4CDF B;  3V6C A;  4RY2 A;  1DKI A;  3BBA A;  1MEG A;  2XU5 A;  3H89 A;  1QMY A;  4X6H A;  2Y6E A;  5F02 A;  2JRI A;  2R9N A;  1X9Y A;  3I3T A;  3HWN A;  3C9E A;  2AIM A;  5EZS A;  1CS8 A;  2DC9 A;  4OEM A;  4QRG A;  4Q8G A;  2FO5 A;  5CVM A;  1HUC B;  5CHT A;  2B1N A;  2PNS A;  2PAD A;  2ARY A;  1ICF A;  3OQC A;  2PBH A;  1PE6 A;  2AYN A;  4BPV A;  2G8E A;  3PHX A;  1QDQ A;  2VHF A;  2DCD A;  1NL6 A;  3H6S A;  2P0R A;  3K9M A;  4I07 A;  3S3Q A;  3PHW A;  2AYO A;  2G6D A;  4OVZ A;  5E6J A;  1U9Q X;  3OVZ A;  3MJ5 A;  2HHN A;  4RNA A;  2G8J A;  2UZJ A;  2R9F A;  4N4Z A;  4OEL A;  3BB7 A;  1AIM A;  3GCB A;  3B21 A;  3P5X A;  3OF9 A;  3TMP A;  4HWY A;  1IWD A;  1F2C A;  1QXP A;  2WBF X;  5CHV A;  5CVN B;  3K24 A;  4AXM A;  1PPP A;  3PNR A;  2DC6 A;  4A5U A;  4QBB A;  5CVO B;  3C0R A;  4W5B A;  1F29 A;  4RKX A;  2GHU A;  1EWP A;  4BOZ A;  1AYU A;  2C0Y A;  3BOW A;  1VJV A;  2XU1 A;  5FPW A;  1PPN A;  4DMX A;  5EF4 A;  4BOQ A;  2R9C A;  3KX1 A;  3LFY A;  4D8E A;  1XKG A;  1BQI A;  3CH2 X;  3NHE A;  4W5C A;  1SNK A;  1YK7 A;  4RF0 A;  1PCI A;  3IMA A;  3PW3 A;  3BY4 A;  4XZX A;  3U8E A;  1PBH A;  2JQF R;  2O6X A;  2XU3 A;  2AS8 A;  1KFU L;  1U9V A;  2DCC A;  2BDL A;  2PRE A;  1STF E;  1PXV A;  1VSN A;  1JQP A;  1PPO A;  5JH3 A;  7PCK A;  3BPM A;  4BS5 A;  3RVV A;  3QSD A;  2FRA A;  1DF0 A;  1PVJ A;  3E1Z B;  3P5U A;  4BS6 A;  5K16 A;  1AYW A;  1Y4H A;  3OVX A;  1FH0 A;  1ZIV A;  2IBI A;  1GMY A;  2FYE A;  1YK8 A;  3I06 A;  4G54 A;  1TL9 A;  1AU2 A;  8PCH A;  4N79 A;  2J7Q A;  3H7D A;  3N3G A;  5EZQ A;  3K8U A;  9PAP A;  3QT4 A;  2AUZ A;  1MS6 A;  2DZZ A;  2DJF B;  3KFQ A;  3PDF A;  1NLJ A;  4OW0 A;  1AU3 A;  2AVW A;  1GCB A;  2HD5 A;  4YYS A;  2OP3 A;  1MIR A;  5J94 A;  2BTW B;  1QOL A;  1ATK A;  4P6E A;  3PSE A;  2HWK A;  2H7J A;  3ZNH A;  1UKF A;  4P6G A;  1GLO A;  3BPF A;  1PPD A;  2NQD B;  1PAD A;  4D8B A;  1THE A;  3MTV A;  3ERV A;  1AYV A;  2R9O A;  2P7U A; 
#chains in the Genus database with same CATH homology
 1W6F A;  1CSB B;  1E2T A;  4YYW A;  1TLO A;  3F5V A;  3IV2 A;  3RVW A;  3IHP A;  3WXF A;  2B1M A;  1KXR A;  1S4V A;  1NB3 A;  1ME3 A;  2Y5B A;  2JQG R;  4CDD B;  3KW9 A;  4X6I A;  4CDC B;  4WA6 A;  3KWZ A;  2F1G A;  3KSE A;  4MZS A;  3MHH A;  2YJB A;  1CJL A;  1EWO A;  2F7D A;  4GUZ A;  3BCN A;  1CB5 A;  1BGO A;  2HH5 A;  1YT7 A;  1O0E A;  3IEJ A;  3D6S A;  4FJC A;  4PP1 A;  1ZCM A;  1W5R A;  3WXE A;  2CIO A;  4QRX A;  4KLB A;  1EF7 A;  2DZY A;  3H8B A;  3TNX A;  3OIS A;  4C5P A;  1AEC A;  2XU4 A;  3P5W A;  2FRQ A;  3WXG A;  1ITO A;  1M6D A;  2OUL A;  3BC3 A;  3KWB X;  3MHS A;  4BSQ A;  2YJ8 A;  2GFO A;  1EWM A;  1U9X A;  4Q8H A;  4N8W A;  3DF0 A;  3N4C A;  1KFX L;  1Y08 A;  2E00 A;  1MHW A;  3O1G A;  3PBH A;  4QRV A;  4YYV A;  3M99 A;  4XUI A;  2R6N A;  1K3B B;  1AU0 A;  2ATO A;  2DJG B;  3P5V A;  2E02 A;  1NQC A;  1NPZ A;  6PAD A;  1EWL A;  1A6R A;  2NQG A;  4XR7 A;  2BDZ A;  2YJC A;  3CBK A;  2AUX A;  2IPP B;  3CH3 X;  4NV8 A;  2OZ2 A;  2E03 A;  2DCB A;  1CV8 A;  4DMY A;  3HD3 A;  1CPJ A;  2FT2 A;  1POP A;  3ZUA A;  4YVA A;  4YV8 A;  4FIP A;  4YYU A;  1YVB A;  3N3K A;  3B79 A;  2DCA A;  3KKU A;  2HXZ A;  1SP4 B;  3MOR A;  1BY8 A;  1CTE A;  3MTN A;  4CZW A;  2DC8 A;  4BGF A;  4PP2 E;  2FQ9 A;  2R9M A;  4PI3 A;  5EGW A;  1F2B A;  4MSX A;  2E01 A;  3HHI A;  1F2A A;  3QJ3 A;  1CVZ A;  1MDW A;  1PIP A;  1ME4 A;  2ACT A;  3BWK A;  2NQI A;  3OF8 A;  5A24 A;  4I05 A;  1U9W A;  2YJ9 A;  1U5I A;  3IOQ A;  4X6J A;  3IUT A;  1BP4 A;  4YYR A;  2AU1 A;  4MZO A;  3RVX A;  3AI8 A;  1TU6 A;  4I04 A;  3V6E A;  3O0U A;  4BQV A;  2DC7 A;  4QH6 A;  2CB5 A;  1AU4 A;  2NQA A;  4PAD A;  2FUD A;  2G7Y A;  1YAL A;  4FK5 A;  1NB5 A;  4CDE B;  2P86 A;  1MEM A;  3CBJ A;  4K7C A;  1DEU A;  2FTD A;  3HHA A;  3LXS A;  2VHS A;  2YJ2 A;  4YYQ A;  3F75 A;  5PAD A;  5JA7 A;  1KHP A;  4AXL A;  1CQD A;  4W4U A;  1GEC E;  3S3R A;  1KHQ A;  4ZUX U;  3H8C A;  1Q6K A;  3USV A;  4CDF B;  3V6C A;  4RY2 A;  1MEG A;  2BSZ A;  2XU5 A;  3H89 A;  1QMY A;  4X6H A;  2Y6E A;  5F02 A;  2R9N A;  1X9Y A;  3I3T A;  3HWN A;  3C9E A;  2AIM A;  1W4T A;  1CS8 A;  2DC9 A;  4OEM A;  4QRG A;  4Q8G A;  2FO5 A;  5CVM A;  1HUC B;  5CHT A;  2B1N A;  2PNS A;  2PAD A;  2ARY A;  1ICF A;  2PBH A;  1PE6 A;  2AYN A;  4BPV A;  2G8E A;  1QDQ A;  2VHF A;  2DCD A;  2VFB A;  1NL6 A;  3H6S A;  2P0R A;  3K9M A;  4I07 A;  3S3Q A;  2AYO A;  2G6D A;  1U9Q X;  3OVZ A;  3LTW A;  2HHN A;  2G8J A;  2R9F A;  4N4Z A;  4OEL A;  1AIM A;  3GCB A;  3P5X A;  3OF9 A;  4HWY A;  1IWD A;  1F2C A;  1QXP A;  2WBF X;  5CHV A;  5CVN B;  3K24 A;  4AXM A;  1PPP A;  3PNR A;  2DC6 A;  4QBB A;  5CVO B;  4W5B A;  1F29 A;  2GHU A;  1EWP A;  1AYU A;  2C0Y A;  3BOW A;  1VJV A;  2XU1 A;  5FPW A;  1PPN A;  4DMX A;  5EF4 A;  2R9C A;  3KX1 A;  3LFY A;  1XKG A;  1BQI A;  3CH2 X;  3NHE A;  4W5C A;  1SNK A;  1YK7 A;  1PCI A;  3IMA A;  3PW3 A;  3U8E A;  1PBH A;  2JQF R;  2O6X A;  2XU3 A;  2AS8 A;  1KFU L;  1U9V A;  2DCC A;  2BDL A;  2PRE A;  1STF E;  2VFC A;  1PXV A;  1VSN A;  1JQP A;  4NV7 A;  1PPO A;  5JH3 A;  7PCK A;  3BPM A;  4BS5 A;  3RVV A;  3QSD A;  2FRA A;  1DF0 A;  3E1Z B;  3P5U A;  4BS6 A;  5K16 A;  1AYW A;  1Y4H A;  3OVX A;  1FH0 A;  1ZIV A;  2IBI A;  1GMY A;  2FYE A;  1YK8 A;  3I06 A;  4G54 A;  1TL9 A;  1AU2 A;  4B55 A;  8PCH A;  4N79 A;  3D9W A;  3H7D A;  3N3G A;  3K8U A;  9PAP A;  3QT4 A;  2AUZ A;  1MS6 A;  2DZZ A;  2DJF B;  3KFQ A;  3PDF A;  1NLJ A;  1AU3 A;  2AVW A;  1GCB A;  2HD5 A;  4YYS A;  2OP3 A;  1MIR A;  1GX3 A;  5J94 A;  1QOL A;  1ATK A;  4P6E A;  2H7J A;  4P6G A;  1GLO A;  3BPF A;  1PPD A;  2NQD B;  1PAD A;  1THE A;  3ERV A;  1AYV A;  2R9O A;  2P7U A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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