4BOSA

Structure of otud2 otu domain in complex with ubiquitin k11-linked peptide
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
164
structure length
164
Chain Sequence
GPVLTRTVVPADNSALFTSVYYVVEGGVLNPACAPEMRRLIAQIVASDPDFYSEAILGKTNQEYCDWIKRDDTWGGAIEISILSKFYQCEICVVDTQTVRIDRFGEDAGYTKRVLLIYDGIHYDPLQRNFPDPDTPPLTIFSSNDDIVLVQALELADEARRRRQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Otu Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords UBIQUITIN THIOESTERASE OTU1
total genus 50
structure length 164
sequence length 164
chains with identical sequence B
ec nomenclature ec 3.4.19.12: Ubiquitinyl hydrolase 1.
pdb deposition date 2013-05-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02338 OTU OTU-like cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.80 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cathepsin B; Chain A 4bosA00
3PHUA 4BOUA 4BOSA 4BOZA 3PHXA 3TMPA 3ZNHA 3PSEA 3BY4A 4BOQA 3PHWA 4BOPA 4HXDB 3C0RA 3PRPA 3PRMA 5JZEA 3PT2A
chains in the Genus database with same CATH superfamily
4BOUA 3W31A 3BPMA 1TU6A 4YYSA 1Y08A 1QOLA 2R9CA 3F75A 1ATKA 2BTWB 3H8BA 3PNRA 1U9QX 1BQIA 4WA6A 3MTVA 4OW0A 2AYNA 4QRXA 5FPWA 4BSQA 4YVAA 2OZ2A 1KFXL 2B1MA 4K7CA 2WBFX 3PBHA 2AUZA 4Q8HA 3ERVA 3C9EA 1NB5A 4W5BA 5JA7A 1F2CA 3GCBA 2NQGA 3PSEA 1CPJA 4IUMA 4P6EA 4D8BA 1U9XA 4YYUA 9PAPA 1GECE 3OF8A 3PHWA 4RKXA 4ZUXU 5PADA 4G54A 3QT4A 1EWPA 2Y5BA 1F29A 2XU1A 2AUXA 1SP4B 1MEMA 1BY8A 5CVMA 5KO3A 1PIPA 3RVXA 3IFUA 2G6DA 1DKIA 3O65A 2AVWA 2GFOA 1ICFA 3RVVA 4N8WA 1PPOA 1ME4A 3PRMA 8PCHA 3E9SA 3PRPA 4PI3A 2E03A 2O6XA 3MP2A 3H8CA 1VJVA 1CV8A 1QDQA 3B21A 5EZSA 3M99A 2FRQA 1CS8A 2J7QA 2F7DA 4PP2E 5E6JA 3PT2A 2DC8A 3BC3A 3RNVA 4IP3A 2FYEA 1MS6A 4FJCA 2JRIA 2YJ2A 2HH5A 1BGOA 4P6GA 2R9MA 3TNXA 2G8JA 1MDWA 2NQAA 3HD3A 3OVXA 4N79A 1KHPA 4I04A 4BPVA 4YYQA 3KWBX 4RF1A 2E00A 3BWKA 3PDFA 1PPPA 1YVBA 4YYWA 3I06A 3OQCA 2BDZA 2AYOA 4DMYA 3U8EA 3BY4A 3QSDA 3N3KA 3WXFA 3IOQA 3BCNA 3PHXA 3ZNHA 2P86A 1JQPA 1S4VA 1ME3A 5CHVA 4RF0A 4M0WA 2FE8A 2OULA 4QH6A 3BB7A 1CTEA 4CDDB 4N4ZA 1CJLA 1POPA 1XKGA 1MIRA 2FTDA 3HHAA 3K9MA 2FO5A 1TLOA 1X9YA 1EWMA 1AYVA 2DZZA 2DZYA 3CH3X 1PVJA 3IMAA 1YZBA 4REZA 1Q6KA 1KXRA 3TRKA 2AU1A 2HHNA 1NLJA 2JQGR 4D8EA 4W5CA 3RVWA 1ZCMA 1CSBB 4MZOA 3H89A 2G8EA 4I07A 2R9OA 3N4CA 3OF9A 4PADA 1NB3A 3BBAA 4BQVA 1U9VA 3KFQA 2P7UA 1IWDA 2YJBA 2DJGB 3K24A 2AIMA 1F2BA 4W4UA 4I05A 1AECA 2VHFA 2Z84A 2R9FA 1K3BB 3IUTA 4PT5A 1PE6A 3WXGA 1U5IA 4Q8GA 2JTCA 2F1GA 2JQFR 3K8UA 1CVZA 3BOWA 1QMYA 2DC7A 3KX1A 4RNAA 3F5VA 2BU3A 1NPZA 4OEMA 2Y6EA 2HXZA 4BOPA 1DF0A 2B1NA 6PADA 1CB5A 1GCBA 1AU0A 1NQCA 2DC9A 4PP1A 3MHSA 3CH2X 1F2AA 4QRVA 3PW3A 4XZXA 5EZQA 2YJ8A 4OVZA 2ARYA 4X6IA 1A6RA 2DJFB 3P5XA 1CQDA 2P0RA 4A5UA 1GMYA 4CDEB 5EF4A 1KFUL 3PHUA 4YYRA 4R3DA 1M6DA 4BOZA 3NHEA 7PCKA 1VSNA 1PCIA 1BP4A 4CDFB 3S3QA 2XU3A 2C0YA 4AXMA 4BS6A 2HD5A 4MSXA 4WURA 1QXPA 3P5UA 3HHIA 3I3TA 4OVZB 2FT2A 3O0UA 2XU5A 1PXVA 3OISA 2PADA 1EF7A 2J7QC 5CVOB 2DCBA 2FQ9A 1U9WA 4YYVA 1NL6A 2CIOA 1TL9A 1SNKA 1YK8A 4BS5A 2CB5A 1MEGA 2HWKA 3S3RA 2GHUA 4GUAA 3WXEA 4RY2A 3KSEA 3ZUAA 3TMPA 4D8IA 5F02A 4QBBA 1AU3A 5JH3A 5J94A 1AU4A 3BPFA 2DCCA 3LXSA 4FIPA 4HWYA 3D6SA 2UZJA 2PREA 1YK7A 4BOQA 4FK5A 1PBHA 3O1GA 1ITOA 3N3GA 1DEUA 3OVZA 2E02A 3H6SA 5JZEA 1GLOA 1UKFA 3IEJA 3MORA 3AI8A 3IV2A 3V6CA 5CHTA 4XR7A 1PPDA 4MM3B 4BOSA 2BDLA 2NQDB 3P5VA 1THEA 4KLBA 3IHPA 2IPPB 2VHSA 2ATOA 4MZSA 3MHHA 4OELA 2OP3A 2ACTA 2FRAA 4XUIA 2DCAA 1Y4HA 1KHQA 4DMXA 1AIMA 2H7JA 5A24A 4P16A 1STFE 2PNSA 4QRGA 1AYUA 2G7YA 4ZTBA 3LFYA 2IBIA 3C0RA 1YT7A 3H7DA 4X6JA 1YALA 1FH0A 3P5WA 2YJ9A 2NQIA 3MTNA 2DC6A 5EGWA 5K16A 3E1ZB 4MI7A 1PADA 2PBHA 2R9NA 4CZWA 2YJCA 3KKUA 1PPNA 3USVA 3KWZA 2AS8A 2FUDA 4AXLA 3CBJA 1HUCB 3HWNA 4HXDB 4CDCB 1ZIVA 1MHWA 2BTWA 3MJ5A 3W30A 2AGAA 4YV8A 2E01A 4X6HA 2DCDA 1AYWA 3B79A 2XU4A 3CBKA 3DF0A 1EWOA 1O0EA 1AU2A 3QJ3A 2R6NA 3KW9A 1EWLA 2DOSA 5CVNB 3V6EA
chains in the Genus database with same CATH topology
4BOUA 3W31A 4BOQA 2Z84A 4PT5A 2BTWB 3MTVA 2JTCA 4OW0A 1UKFA 4RNAA 2BU3A 4BOPA 4RF1A 4MM3B 4BOSA 3PSEA 4IUMA 4D8BA 3OQCA 3BY4A 3PHWA 4RKXA 4XZXA 5EZQA 3PHXA 3ZNHA 4OVZA 4RF0A 4A5UA 4M0WA 4P16A 2FE8A 3PHUA 4R3DA 3BB7A 4ZTBA 4BOZA 5KO3A 3C0RA 3IFUA 1DKIA 3O65A 4WURA 1PVJA 4OVZB 1YZBA 4MI7A 4REZA 3PRMA 3TRKA 3E9SA 2J7QC 3PRPA 4D8EA 4HXDB 3MP2A 2BTWA 3W30A 3MJ5A 2AGAA 3B21A 5EZSA 2HWKA 4GUAA 3BBAA 2J7QA 3TMPA 4D8IA 5E6JA 3PT2A 3RNVA 4IP3A 2UZJA 2DOSA 5JZEA 2JRIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PHU A;  4BOU A;  4BOS A;  4BOZ A;  3PHX A;  3TMP A;  3ZNH A;  3PSE A;  3BY4 A;  4BOQ A;  3PHW A;  4BOP A;  4HXD B;  3C0R A;  3PRP A;  3PRM A;  5JZE A;  3PT2 A; 
#chains in the Genus database with same CATH topology
 4BOU A;  3W31 A;  3BPM A;  1TU6 A;  4YYS A;  1Y08 A;  1QOL A;  2R9C A;  3F75 A;  1ATK A;  2BTW B;  3H8B A;  3PNR A;  1U9Q X;  1BQI A;  4WA6 A;  3MTV A;  4OW0 A;  2AYN A;  4QRX A;  5FPW A;  4BSQ A;  4YVA A;  2OZ2 A;  1KFX L;  2B1M A;  4K7C A;  2WBF X;  3PBH A;  2AUZ A;  4Q8H A;  3ERV A;  3C9E A;  1NB5 A;  4W5B A;  5JA7 A;  1F2C A;  3GCB A;  2NQG A;  3PSE A;  1CPJ A;  4IUM A;  4P6E A;  4D8B A;  1U9X A;  4YYU A;  9PAP A;  1GEC E;  3OF8 A;  3PHW A;  4RKX A;  4ZUX U;  5PAD A;  4G54 A;  3QT4 A;  1EWP A;  2Y5B A;  1F29 A;  2XU1 A;  2AUX A;  1SP4 B;  1MEM A;  1BY8 A;  5CVM A;  5KO3 A;  1PIP A;  3RVX A;  3IFU A;  2G6D A;  1DKI A;  3O65 A;  2AVW A;  2GFO A;  1ICF A;  3RVV A;  4N8W A;  1PPO A;  1ME4 A;  3PRM A;  8PCH A;  3E9S A;  3PRP A;  4PI3 A;  2E03 A;  2O6X A;  3MP2 A;  3H8C A;  1VJV A;  1CV8 A;  1QDQ A;  3B21 A;  5EZS A;  3M99 A;  2FRQ A;  1CS8 A;  2J7Q A;  2F7D A;  4PP2 E;  5E6J A;  3PT2 A;  2DC8 A;  3BC3 A;  3RNV A;  4IP3 A;  2FYE A;  1MS6 A;  4FJC A;  2JRI A;  2YJ2 A;  2HH5 A;  1BGO A;  4P6G A;  2R9M A;  3TNX A;  2G8J A;  1MDW A;  2NQA A;  3HD3 A;  3OVX A;  4N79 A;  1KHP A;  4I04 A;  4BPV A;  4YYQ A;  3KWB X;  4RF1 A;  2E00 A;  3BWK A;  3PDF A;  1PPP A;  1YVB A;  4YYW A;  3I06 A;  3OQC A;  2BDZ A;  2AYO A;  4DMY A;  3U8E A;  3BY4 A;  3QSD A;  3N3K A;  3WXF A;  3IOQ A;  3BCN A;  3PHX A;  3ZNH A;  2P86 A;  1JQP A;  1S4V A;  1ME3 A;  5CHV A;  4RF0 A;  4M0W A;  2FE8 A;  2OUL A;  4QH6 A;  3BB7 A;  1CTE A;  4CDD B;  4N4Z A;  1CJL A;  1POP A;  1XKG A;  1MIR A;  2FTD A;  3HHA A;  3K9M A;  2FO5 A;  1TLO A;  1X9Y A;  1EWM A;  1AYV A;  2DZZ A;  2DZY A;  3CH3 X;  1PVJ A;  3IMA A;  1YZB A;  4REZ A;  1Q6K A;  1KXR A;  3TRK A;  2AU1 A;  2HHN A;  1NLJ A;  2JQG R;  4D8E A;  4W5C A;  3RVW A;  1ZCM A;  1CSB B;  4MZO A;  3H89 A;  2G8E A;  4I07 A;  2R9O A;  3N4C A;  3OF9 A;  4PAD A;  1NB3 A;  3BBA A;  4BQV A;  1U9V A;  3KFQ A;  2P7U A;  1IWD A;  2YJB A;  2DJG B;  3K24 A;  2AIM A;  1F2B A;  4W4U A;  4I05 A;  1AEC A;  2VHF A;  2Z84 A;  2R9F A;  1K3B B;  3IUT A;  4PT5 A;  1PE6 A;  3WXG A;  1U5I A;  4Q8G A;  2JTC A;  2F1G A;  2JQF R;  3K8U A;  1CVZ A;  3BOW A;  1QMY A;  2DC7 A;  3KX1 A;  4RNA A;  3F5V A;  2BU3 A;  1NPZ A;  4OEM A;  2Y6E A;  2HXZ A;  4BOP A;  1DF0 A;  2B1N A;  6PAD A;  1CB5 A;  1GCB A;  1AU0 A;  1NQC A;  2DC9 A;  4PP1 A;  3MHS A;  3CH2 X;  1F2A A;  4QRV A;  3PW3 A;  4XZX A;  5EZQ A;  2YJ8 A;  4OVZ A;  2ARY A;  4X6I A;  1A6R A;  2DJF B;  3P5X A;  1CQD A;  2P0R A;  4A5U A;  1GMY A;  4CDE B;  5EF4 A;  1KFU L;  3PHU A;  4YYR A;  4R3D A;  1M6D A;  4BOZ A;  3NHE A;  7PCK A;  1VSN A;  1PCI A;  1BP4 A;  4CDF B;  3S3Q A;  2XU3 A;  2C0Y A;  4AXM A;  4BS6 A;  2HD5 A;  4MSX A;  4WUR A;  1QXP A;  3P5U A;  3HHI A;  3I3T A;  4OVZ B;  2FT2 A;  3O0U A;  2XU5 A;  1PXV A;  3OIS A;  2PAD A;  1EF7 A;  2J7Q C;  5CVO B;  2DCB A;  2FQ9 A;  1U9W A;  4YYV A;  1NL6 A;  2CIO A;  1TL9 A;  1SNK A;  1YK8 A;  4BS5 A;  2CB5 A;  1MEG A;  2HWK A;  3S3R A;  2GHU A;  4GUA A;  3WXE A;  4RY2 A;  3KSE A;  3ZUA A;  3TMP A;  4D8I A;  5F02 A;  4QBB A;  1AU3 A;  5JH3 A;  5J94 A;  1AU4 A;  3BPF A;  2DCC A;  3LXS A;  4FIP A;  4HWY A;  3D6S A;  2UZJ A;  2PRE A;  1YK7 A;  4BOQ A;  4FK5 A;  1PBH A;  3O1G A;  1ITO A;  3N3G A;  1DEU A;  3OVZ A;  2E02 A;  3H6S A;  5JZE A;  1GLO A;  1UKF A;  3IEJ A;  3MOR A;  3AI8 A;  3IV2 A;  3V6C A;  5CHT A;  4XR7 A;  1PPD A;  4MM3 B;  4BOS A;  2BDL A;  2NQD B;  3P5V A;  1THE A;  4KLB A;  3IHP A;  2IPP B;  2VHS A;  2ATO A;  4MZS A;  3MHH A;  4OEL A;  2OP3 A;  2ACT A;  2FRA A;  4XUI A;  2DCA A;  1Y4H A;  1KHQ A;  4DMX A;  1AIM A;  2H7J A;  5A24 A;  4P16 A;  1STF E;  2PNS A;  4QRG A;  1AYU A;  2G7Y A;  4ZTB A;  3LFY A;  2IBI A;  3C0R A;  1YT7 A;  3H7D A;  4X6J A;  1YAL A;  1FH0 A;  3P5W A;  2YJ9 A;  2NQI A;  3MTN A;  2DC6 A;  5EGW A;  5K16 A;  3E1Z B;  4MI7 A;  1PAD A;  2PBH A;  2R9N A;  4CZW A;  2YJC A;  3KKU A;  1PPN A;  3USV A;  3KWZ A;  2AS8 A;  2FUD A;  4AXL A;  3CBJ A;  1HUC B;  3HWN A;  4HXD B;  4CDC B;  1ZIV A;  1MHW A;  2BTW A;  3MJ5 A;  3W30 A;  2AGA A;  4YV8 A;  2E01 A;  4X6H A;  2DCD A;  1AYW A;  3B79 A;  2XU4 A;  3CBK A;  3DF0 A;  1EWO A;  1O0E A;  1AU2 A;  3QJ3 A;  2R6N A;  3KW9 A;  1EWL A;  2DOS A;  5CVN B;  3V6E A; 
#chains in the Genus database with same CATH homology
 4BOU A;  3W31 A;  4BOQ A;  2Z84 A;  4PT5 A;  2BTW B;  3MTV A;  2JTC A;  4OW0 A;  1UKF A;  4RNA A;  2BU3 A;  4BOP A;  4RF1 A;  4MM3 B;  4BOS A;  3PSE A;  4IUM A;  4D8B A;  3OQC A;  3BY4 A;  3PHW A;  4RKX A;  4XZX A;  5EZQ A;  3PHX A;  3ZNH A;  4OVZ A;  4RF0 A;  4A5U A;  4M0W A;  4P16 A;  2FE8 A;  3PHU A;  4R3D A;  3BB7 A;  4ZTB A;  4BOZ A;  5KO3 A;  3C0R A;  3IFU A;  1DKI A;  3O65 A;  4WUR A;  1PVJ A;  4OVZ B;  1YZB A;  4MI7 A;  4REZ A;  3PRM A;  3TRK A;  3E9S A;  2J7Q C;  3PRP A;  4D8E A;  4HXD B;  3MP2 A;  2BTW A;  3W30 A;  3MJ5 A;  2AGA A;  3B21 A;  5EZS A;  2HWK A;  4GUA A;  3BBA A;  2J7Q A;  3TMP A;  4D8I A;  5E6J A;  3PT2 A;  3RNV A;  4IP3 A;  2UZJ A;  2DOS A;  5JZE A;  2JRI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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