3OVZA

Cathepsin k in complex with a covalent inhibitor with a ketoamide warhead
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
213
structure length
213
Chain Sequence
DSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Trifluoromethylphenyl as P2 for ketoamide-based cathepsin S inhibitors.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Cathepsin K
total genus 63
structure length 213
sequence length 213
ec nomenclature ec 3.4.22.38: Cathepsin K.
pdb deposition date 2010-09-17
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 3ovzA00
5CVNB 1U9XA 3KKUA 2JQGR 2F1GA 1KXRA 2NQGA 3V6CA 4P6GA 4X6JA 1NPZA 4QH6A 5K16A 2AYNA 2AYOA 2OP3A 3KWBX 3I3TA 3OVZA 2JQFR 2PNSA 3MHHA 3H7DA 4CDEB 3V6EA 2Y5BA 4YYSA 3CH3X 4CDDB 4YV8A 4YYWA 1AU2A 2B1NA 3TNXA 1F29A 4OELA 2F7DA 2HHNA 1CTEA 3BC3A 1CS8A 1CPJA 1F2BA 4PADA 3HHAA 1U5IA 4I04A 4AXLA 1PBHA 3AI8A 1ZIVA 3BCNA 2AUZA 1VJVA 4W5BA 3QT4A 5CVOB 3K24A 3K8UA 1ME3A 2PADA 4G54A 4PP2E 2DJGB 4ZUXU 2OULA 3BWKA 2GHUA 5CHTA 2YJ2A 1JQPA 1AU0A 1ME4A 3U8EA 2R9FA 2C0YA 4PI3A 3N3KA 2G6DA 1X9YA 4FJCA 5J94A 3MHSA 3O0UA 4I05A 2DC8A 1NB3A 5JH3A 1AU4A 3E1ZB 4MZSA 2YJ9A 2CB5A 1AYVA 1O0EA 1U9VA 1STFE 2E00A 1F2CA 3H6SA 1BY8A 2IBIA 1VSNA 3CH2X 1ITOA 1QMYA 1TLOA 1SP4B 4DMXA 7PCKA 3O1GA 3RVWA 1SNKA 4RY2A 1Y08A 5PADA 3HWNA 2CIOA 4FK5A 1EWOA 2R9OA 2NQIA 2DCBA 1M6DA 4OEMA 3N4CA 1CV8A 2NQDB 2E03A 4MZOA 4P6EA 1YVBA 4X6IA 3ERVA 4XR7A 1TU6A 3HD3A 1AYWA 4Q8HA 4QRXA 4K7CA 1XKGA 1EWLA 4W5CA 4CDFB 1K3BB 1CSBB 2FT2A 1PIPA 2BDLA 2DJFB 2FTDA 4CZWA 1GLOA 5A24A 3F5VA 1BP4A 2HXZA 3KW9A 1POPA 4WA6A 4I07A 3CBKA 1HUCB 1EWMA 1NLJA 2ACTA 3CBJA 3OISA 3PBHA 3OF9A 2WBFX 3PNRA 6PADA 3KSEA 3H8CA 2P0RA 1ATKA 3PDFA 2O6XA 2R9CA 1PE6A 4QRVA 1DF0A 4XUIA 3IV2A 3K9MA 2DCDA 4MSXA 1ICFA 2NQAA 3NHEA 1S4VA 4YYUA 1GECE 1YT7A 3DF0A 2AU1A 4QBBA 1Q6KA 3KX1A 2ATOA 2OZ2A 3KFQA 4N79A 2R9NA 4CDCB 4N8WA 2DC7A 8PCHA 3PW3A 3ZUAA 1KHQA 1U9WA 2DC9A 2E01A 4YYQA 1NQCA 2DZZA 3MTNA 1PADA 5F02A 2DCAA 1KHPA 3KWZA 4KLBA 1AU3A 1PCIA 4PP1A 3RVVA 1EF7A 1MS6A 3C9EA 2XU3A 2R6NA 9PAPA 1BGOA 2G8EA 1PPNA 1CB5A 1PXVA 3WXEA 1CVZA 4X6HA 3N3GA 1AECA 1QXPA 2VHFA 3IHPA 2HD5A 2H7JA 3H8BA 3LXSA 3OF8A 1MDWA 1MIRA 1AIMA 4BPVA 4N4ZA 2YJBA 1CJLA 2FQ9A 3S3RA 2G7YA 2DZYA 2FRAA 2FO5A 3GCBA 3F75A 1QDQA 4YYVA 3IEJA 4FIPA 4DMYA 4HWYA 4BQVA 1ZCMA 3BPFA 3P5XA 1YK8A 1KFUL 3LFYA 1CQDA 1MEMA 4W4UA 4YVAA 2DC6A 4Q8GA 2AIMA 2PREA 1FH0A 3S3QA 1GCBA 3P5WA 1TL9A 2ARYA 2FYEA 2B1MA 3B79A 3RVXA 2XU5A 5EF4A 2AVWA 3IOQA 2BDZA 2XU1A 3HHIA 2G8JA 1NL6A 3MORA 1F2AA 2GFOA 3IUTA 2E02A 1YK7A 3IMAA 1THEA 2Y6EA 5FPWA 1PPPA 5EGWA 2P7UA 4BS5A 2FUDA 2YJ8A 1BQIA 1AYUA 2FRQA 1MEGA 4AXMA 1DEUA 4BSQA 1PPOA 1KFXL 3M99A 3OVXA 2P86A 3QSDA 3WXGA 3D6SA 2AUXA 1PPDA 4YYRA 5CHVA 2IPPB 1GMYA 3P5UA 3USVA 3WXFA 1IWDA 1Y4HA 3H89A 2VHSA 2R9MA 1QOLA 4BS6A 3QJ3A 2PBHA 1EWPA 1U9QX 3P5VA 2HH5A 1MHWA 3BPMA 4QRGA 3I06A 5JA7A 2DCCA 2YJCA 2AS8A 3BOWA 1NB5A 2XU4A 1YALA 1A6RA 5CVMA
chains in the Genus database with same CATH superfamily
5CVNB 1U9XA 3KKUA 2JQGR 2F1GA 1KXRA 2NQGA 3IFUA 2HWKA 3V6CA 3ZNHA 2AGAA 4P6GA 4RF1A 4ZTBA 4X6JA 1NPZA 4QH6A 5K16A 5EZQA 4WURA 2AYNA 2AYOA 2OP3A 3KWBX 3I3TA 3OVZA 2JQFR 2PNSA 3MHHA 3H7DA 4CDEB 3V6EA 2Y5BA 4YYSA 3CH3X 4CDDB 4YV8A 4YYWA 1AU2A 2B1NA 3TNXA 3PRPA 1F29A 4OELA 4REZA 2F7DA 2HHNA 1CTEA 3BC3A 1CS8A 1CPJA 1F2BA 3C0RA 4PADA 3HHAA 1U5IA 4I04A 4AXLA 1PBHA 3E9SA 3AI8A 1ZIVA 3BCNA 2AUZA 1VJVA 4W5BA 3QT4A 5CVOB 3K24A 3K8UA 1ME3A 2PADA 4G54A 3W30A 4PP2E 2DJGB 4ZUXU 2OULA 3BWKA 2GHUA 5CHTA 2YJ2A 1JQPA 1AU0A 1ME4A 4XZXA 3U8EA 2R9FA 2C0YA 4PI3A 3N3KA 2G6DA 1X9YA 4FJCA 5J94A 3MHSA 3O0UA 4I05A 4MM3B 2DC8A 2UZJA 1NB3A 5JH3A 1AU4A 3E1ZB 4IUMA 4MZSA 4OW0A 4OVZA 2YJ9A 2CB5A 1AYVA 1O0EA 1U9VA 1STFE 2E00A 1F2CA 3H6SA 1BY8A 2IBIA 1VSNA 3CH2X 1ITOA 3PT2A 1QMYA 1TLOA 1SP4B 4DMXA 7PCKA 3O1GA 3RVWA 1SNKA 4RF0A 4RY2A 1Y08A 5PADA 3HWNA 2CIOA 4FK5A 1EWOA 2R9OA 2NQIA 2DCBA 1M6DA 4OEMA 3N4CA 1CV8A 2NQDB 2FE8A 4OVZB 2E03A 4MZOA 4P6EA 1YVBA 2BTWA 3MJ5A 3ERVA 4X6IA 5JZEA 4XR7A 1TU6A 3HD3A 1AYWA 4Q8HA 4QRXA 4K7CA 1XKGA 1EWLA 4W5CA 4CDFB 1K3BB 1CSBB 2FT2A 1PIPA 2BDLA 2DJFB 2FTDA 4CZWA 4A5UA 1GLOA 5A24A 3F5VA 1BP4A 2HXZA 3KW9A 1POPA 4WA6A 4I07A 4MI7A 3CBKA 1HUCB 1EWMA 1NLJA 2ACTA 3CBJA 3OISA 3PBHA 3OF9A 2WBFX 3PNRA 6PADA 3KSEA 3H8CA 2BTWB 1DKIA 3TRKA 4BOPA 2P0RA 1ATKA 3PDFA 2O6XA 2R9CA 1PE6A 4QRVA 1DF0A 4XUIA 3PRMA 4R3DA 3IV2A 5EZSA 3K9MA 2DCDA 4MSXA 4BOSA 1ICFA 2NQAA 3BY4A 3NHEA 1S4VA 4YYUA 1GECE 1YT7A 3DF0A 2AU1A 4QBBA 1Q6KA 3KX1A 2ATOA 2OZ2A 3KFQA 4N79A 1UKFA 2R9NA 3PHWA 4CDCB 4N8WA 2DC7A 8PCHA 3PW3A 3ZUAA 1KHQA 1U9WA 2DC9A 2E01A 4RKXA 4YYQA 4BOUA 1NQCA 2DZZA 3MTNA 1PADA 5F02A 2DCAA 1KHPA 5KO3A 3KWZA 4KLBA 1AU3A 1PCIA 4PP1A 3RVVA 1EF7A 1MS6A 3C9EA 2XU3A 2R6NA 9PAPA 4IP3A 1BGOA 2BU3A 2G8EA 3O65A 1PPNA 1CB5A 1PXVA 3WXEA 1YZBA 3BBAA 1CVZA 4X6HA 3MP2A 3PHXA 3N3GA 1AECA 1QXPA 2VHFA 3RNVA 3IHPA 2HD5A 2H7JA 2Z84A 3H8BA 3LXSA 3OF8A 1MDWA 1MIRA 1AIMA 4BPVA 4N4ZA 2YJBA 3BB7A 4PT5A 1CJLA 2FQ9A 3PSEA 2JTCA 3S3RA 2G7YA 2DZYA 5E6JA 2FRAA 2FO5A 3GCBA 4BOQA 3F75A 4BOZA 4M0WA 1QDQA 4YYVA 3IEJA 4FIPA 4DMYA 4HWYA 4BQVA 1ZCMA 3BPFA 3P5XA 1YK8A 1KFUL 3LFYA 1CQDA 2DOSA 1MEMA 4W4UA 4YVAA 2DC6A 3B21A 4Q8GA 2AIMA 2PREA 4D8BA 1PVJA 1FH0A 3S3QA 1GCBA 3P5WA 1TL9A 2ARYA 2FYEA 4GUAA 2B1MA 3B79A 3RVXA 2XU5A 5EF4A 4P16A 3OQCA 2AVWA 3IOQA 2BDZA 2XU1A 3HHIA 2G8JA 1NL6A 3MORA 1F2AA 4D8EA 2GFOA 3IUTA 2E02A 1YK7A 3IMAA 1THEA 2Y6EA 5FPWA 2J7QA 3TMPA 1PPPA 5EGWA 2P7UA 4BS5A 4RNAA 2FUDA 2YJ8A 1BQIA 1AYUA 2FRQA 1MEGA 4AXMA 1DEUA 4BSQA 1PPOA 1KFXL 3M99A 3OVXA 3W31A 2P86A 3QSDA 3WXGA 3D6SA 2AUXA 1PPDA 2J7QC 4YYRA 5CHVA 2IPPB 1GMYA 3P5UA 3USVA 3PHUA 3WXFA 1IWDA 1Y4HA 3H89A 2VHSA 2R9MA 2JRIA 1QOLA 4BS6A 3QJ3A 2PBHA 1EWPA 1U9QX 3P5VA 2HH5A 1MHWA 3BPMA 4QRGA 3I06A 5JA7A 2DCCA 2YJCA 4HXDB 3MTVA 2AS8A 4D8IA 3BOWA 1NB5A 2XU4A 1YALA 1A6RA 5CVMA
chains in the Genus database with same CATH topology
5CVNB 1U9XA 3KKUA 2JQGR 2F1GA 1KXRA 2NQGA 3V6CA 1W6FA 4P6GA 4X6JA 1NPZA 4QH6A 5K16A 2AYNA 2AYOA 2OP3A 3KWBX 3I3TA 3OVZA 2JQFR 2PNSA 3MHHA 3H7DA 4CDEB 3V6EA 2Y5BA 4YYSA 3CH3X 4CDDB 4YV8A 4YYWA 1AU2A 2B1NA 3TNXA 1F29A 4OELA 2F7DA 2HHNA 1CTEA 3BC3A 1CS8A 1CPJA 1F2BA 4PADA 3HHAA 1U5IA 4I04A 4AXLA 1PBHA 3AI8A 1ZIVA 3BCNA 2AUZA 1VJVA 4W5BA 3QT4A 5CVOB 3K24A 3K8UA 1ME3A 2PADA 4G54A 4PP2E 2DJGB 4ZUXU 2OULA 3BWKA 2GHUA 5CHTA 2YJ2A 1JQPA 1AU0A 1ME4A 3U8EA 2R9FA 2C0YA 4PI3A 1W4TA 3N3KA 2G6DA 1X9YA 4FJCA 5J94A 3MHSA 3O0UA 4I05A 2VFBA 2DC8A 1NB3A 5JH3A 1AU4A 3E1ZB 4MZSA 2YJ9A 2CB5A 1AYVA 1O0EA 1U9VA 1STFE 2E00A 1F2CA 3H6SA 1BY8A 2IBIA 1VSNA 3CH2X 1ITOA 1QMYA 1TLOA 1SP4B 4DMXA 7PCKA 3O1GA 3RVWA 1SNKA 4RY2A 1Y08A 5PADA 3HWNA 2CIOA 4FK5A 1EWOA 2R9OA 2NQIA 2DCBA 1M6DA 4OEMA 3N4CA 1CV8A 2BSZA 2NQDB 2E03A 4MZOA 4P6EA 1YVBA 4X6IA 3ERVA 4XR7A 1TU6A 3HD3A 1AYWA 4Q8HA 4QRXA 4K7CA 1XKGA 1EWLA 4W5CA 4CDFB 1K3BB 1CSBB 2FT2A 1PIPA 2BDLA 2DJFB 2FTDA 4CZWA 1GLOA 5A24A 3F5VA 1BP4A 2HXZA 3KW9A 1POPA 4WA6A 4I07A 3CBKA 1HUCB 1EWMA 1NLJA 2ACTA 3CBJA 3OISA 3PBHA 3OF9A 2WBFX 1E2TA 3PNRA 6PADA 3KSEA 3H8CA 2P0RA 1ATKA 3PDFA 2O6XA 2R9CA 1PE6A 4QRVA 1DF0A 4XUIA 3IV2A 3K9MA 2DCDA 4MSXA 1ICFA 2NQAA 3NHEA 1S4VA 4YYUA 1GECE 1YT7A 3DF0A 2AU1A 4QBBA 1Q6KA 3KX1A 2ATOA 2OZ2A 3KFQA 4NV7A 4N79A 2R9NA 4CDCB 4N8WA 2DC7A 8PCHA 3PW3A 3ZUAA 1KHQA 1U9WA 2DC9A 2E01A 4YYQA 1NQCA 2DZZA 3MTNA 1PADA 5F02A 4GUZA 2DCAA 1KHPA 3KWZA 4KLBA 1AU3A 1PCIA 4PP1A 3RVVA 1EF7A 1MS6A 3C9EA 2XU3A 2R6NA 9PAPA 1BGOA 2G8EA 1PPNA 1CB5A 1PXVA 3WXEA 1CVZA 4X6HA 3N3GA 1AECA 1QXPA 2VHFA 3IHPA 2HD5A 2H7JA 3H8BA 3LXSA 3OF8A 1MDWA 1MIRA 1AIMA 4BPVA 4N4ZA 2YJBA 1CJLA 3D9WA 2FQ9A 3LTWA 3S3RA 2G7YA 2DZYA 2FRAA 2FO5A 3GCBA 3F75A 1QDQA 4YYVA 3IEJA 4FIPA 2VFCA 4DMYA 4HWYA 4BQVA 1ZCMA 3BPFA 4NV8A 3P5XA 1YK8A 1KFUL 3LFYA 1CQDA 1MEMA 4W4UA 4YVAA 2DC6A 4Q8GA 2AIMA 2PREA 4C5PA 1FH0A 3S3QA 1GCBA 3P5WA 1TL9A 2ARYA 2FYEA 2B1MA 3B79A 3RVXA 4BGFA 2XU5A 5EF4A 4B55A 2AVWA 3IOQA 2BDZA 2XU1A 3HHIA 2G8JA 1NL6A 3MORA 1F2AA 2GFOA 3IUTA 2E02A 1YK7A 3IMAA 1THEA 2Y6EA 5FPWA 1PPPA 5EGWA 2P7UA 4BS5A 2FUDA 2YJ8A 1BQIA 1AYUA 2FRQA 1MEGA 4AXMA 1DEUA 4BSQA 1PPOA 1KFXL 3M99A 3OVXA 2P86A 3QSDA 3WXGA 1W5RA 3D6SA 2AUXA 1PPDA 4YYRA 5CHVA 2IPPB 1GMYA 3P5UA 3USVA 3WXFA 1IWDA 1Y4HA 3H89A 2VHSA 2R9MA 1QOLA 4BS6A 3QJ3A 2PBHA 1EWPA 1U9QX 3P5VA 2HH5A 1MHWA 3BPMA 4QRGA 1GX3A 3I06A 5JA7A 2DCCA 2YJCA 2AS8A 3BOWA 1NB5A 2XU4A 1YALA 1A6RA 5CVMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5CVN B;  1U9X A;  3KKU A;  2JQG R;  2F1G A;  1KXR A;  2NQG A;  3V6C A;  4P6G A;  4X6J A;  1NPZ A;  4QH6 A;  5K16 A;  2AYN A;  2AYO A;  2OP3 A;  3KWB X;  3I3T A;  3OVZ A;  2JQF R;  2PNS A;  3MHH A;  3H7D A;  4CDE B;  3V6E A;  2Y5B A;  4YYS A;  3CH3 X;  4CDD B;  4YV8 A;  4YYW A;  1AU2 A;  2B1N A;  3TNX A;  1F29 A;  4OEL A;  2F7D A;  2HHN A;  1CTE A;  3BC3 A;  1CS8 A;  1CPJ A;  1F2B A;  4PAD A;  3HHA A;  1U5I A;  4I04 A;  4AXL A;  1PBH A;  3AI8 A;  1ZIV A;  3BCN A;  2AUZ A;  1VJV A;  4W5B A;  3QT4 A;  5CVO B;  3K24 A;  3K8U A;  1ME3 A;  2PAD A;  4G54 A;  4PP2 E;  2DJG B;  4ZUX U;  2OUL A;  3BWK A;  2GHU A;  5CHT A;  2YJ2 A;  1JQP A;  1AU0 A;  1ME4 A;  3U8E A;  2R9F A;  2C0Y A;  4PI3 A;  3N3K A;  2G6D A;  1X9Y A;  4FJC A;  5J94 A;  3MHS A;  3O0U A;  4I05 A;  2DC8 A;  1NB3 A;  5JH3 A;  1AU4 A;  3E1Z B;  4MZS A;  2YJ9 A;  2CB5 A;  1AYV A;  1O0E A;  1U9V A;  1STF E;  2E00 A;  1F2C A;  3H6S A;  1BY8 A;  2IBI A;  1VSN A;  3CH2 X;  1ITO A;  1QMY A;  1TLO A;  1SP4 B;  4DMX A;  7PCK A;  3O1G A;  3RVW A;  1SNK A;  4RY2 A;  1Y08 A;  5PAD A;  3HWN A;  2CIO A;  4FK5 A;  1EWO A;  2R9O A;  2NQI A;  2DCB A;  1M6D A;  4OEM A;  3N4C A;  1CV8 A;  2NQD B;  2E03 A;  4MZO A;  4P6E A;  1YVB A;  4X6I A;  3ERV A;  4XR7 A;  1TU6 A;  3HD3 A;  1AYW A;  4Q8H A;  4QRX A;  4K7C A;  1XKG A;  1EWL A;  4W5C A;  4CDF B;  1K3B B;  1CSB B;  2FT2 A;  1PIP A;  2BDL A;  2DJF B;  2FTD A;  4CZW A;  1GLO A;  5A24 A;  3F5V A;  1BP4 A;  2HXZ A;  3KW9 A;  1POP A;  4WA6 A;  4I07 A;  3CBK A;  1HUC B;  1EWM A;  1NLJ A;  2ACT A;  3CBJ A;  3OIS A;  3PBH A;  3OF9 A;  2WBF X;  3PNR A;  6PAD A;  3KSE A;  3H8C A;  2P0R A;  1ATK A;  3PDF A;  2O6X A;  2R9C A;  1PE6 A;  4QRV A;  1DF0 A;  4XUI A;  3IV2 A;  3K9M A;  2DCD A;  4MSX A;  1ICF A;  2NQA A;  3NHE A;  1S4V A;  4YYU A;  1GEC E;  1YT7 A;  3DF0 A;  2AU1 A;  4QBB A;  1Q6K A;  3KX1 A;  2ATO A;  2OZ2 A;  3KFQ A;  4N79 A;  2R9N A;  4CDC B;  4N8W A;  2DC7 A;  8PCH A;  3PW3 A;  3ZUA A;  1KHQ A;  1U9W A;  2DC9 A;  2E01 A;  4YYQ A;  1NQC A;  2DZZ A;  3MTN A;  1PAD A;  5F02 A;  2DCA A;  1KHP A;  3KWZ A;  4KLB A;  1AU3 A;  1PCI A;  4PP1 A;  3RVV A;  1EF7 A;  1MS6 A;  3C9E A;  2XU3 A;  2R6N A;  9PAP A;  1BGO A;  2G8E A;  1PPN A;  1CB5 A;  1PXV A;  3WXE A;  1CVZ A;  4X6H A;  3N3G A;  1AEC A;  1QXP A;  2VHF A;  3IHP A;  2HD5 A;  2H7J A;  3H8B A;  3LXS A;  3OF8 A;  1MDW A;  1MIR A;  1AIM A;  4BPV A;  4N4Z A;  2YJB A;  1CJL A;  2FQ9 A;  3S3R A;  2G7Y A;  2DZY A;  2FRA A;  2FO5 A;  3GCB A;  3F75 A;  1QDQ A;  4YYV A;  3IEJ A;  4FIP A;  4DMY A;  4HWY A;  4BQV A;  1ZCM A;  3BPF A;  3P5X A;  1YK8 A;  1KFU L;  3LFY A;  1CQD A;  1MEM A;  4W4U A;  4YVA A;  2DC6 A;  4Q8G A;  2AIM A;  2PRE A;  1FH0 A;  3S3Q A;  1GCB A;  3P5W A;  1TL9 A;  2ARY A;  2FYE A;  2B1M A;  3B79 A;  3RVX A;  2XU5 A;  5EF4 A;  2AVW A;  3IOQ A;  2BDZ A;  2XU1 A;  3HHI A;  2G8J A;  1NL6 A;  3MOR A;  1F2A A;  2GFO A;  3IUT A;  2E02 A;  1YK7 A;  3IMA A;  1THE A;  2Y6E A;  5FPW A;  1PPP A;  5EGW A;  2P7U A;  4BS5 A;  2FUD A;  2YJ8 A;  1BQI A;  1AYU A;  2FRQ A;  1MEG A;  4AXM A;  1DEU A;  4BSQ A;  1PPO A;  1KFX L;  3M99 A;  3OVX A;  2P86 A;  3QSD A;  3WXG A;  3D6S A;  2AUX A;  1PPD A;  4YYR A;  5CHV A;  2IPP B;  1GMY A;  3P5U A;  3USV A;  3WXF A;  1IWD A;  1Y4H A;  3H89 A;  2VHS A;  2R9M A;  1QOL A;  4BS6 A;  3QJ3 A;  2PBH A;  1EWP A;  1U9Q X;  3P5V A;  2HH5 A;  1MHW A;  3BPM A;  4QRG A;  3I06 A;  5JA7 A;  2DCC A;  2YJC A;  2AS8 A;  3BOW A;  1NB5 A;  2XU4 A;  1YAL A;  1A6R A;  5CVM A; 
#chains in the Genus database with same CATH topology
 5CVN B;  1U9X A;  3KKU A;  2JQG R;  2F1G A;  1KXR A;  2NQG A;  3IFU A;  2HWK A;  3V6C A;  3ZNH A;  2AGA A;  4P6G A;  4RF1 A;  4ZTB A;  4X6J A;  1NPZ A;  4QH6 A;  5K16 A;  5EZQ A;  4WUR A;  2AYN A;  2AYO A;  2OP3 A;  3KWB X;  3I3T A;  3OVZ A;  2JQF R;  2PNS A;  3MHH A;  3H7D A;  4CDE B;  3V6E A;  2Y5B A;  4YYS A;  3CH3 X;  4CDD B;  4YV8 A;  4YYW A;  1AU2 A;  2B1N A;  3TNX A;  3PRP A;  1F29 A;  4OEL A;  4REZ A;  2F7D A;  2HHN A;  1CTE A;  3BC3 A;  1CS8 A;  1CPJ A;  1F2B A;  3C0R A;  4PAD A;  3HHA A;  1U5I A;  4I04 A;  4AXL A;  1PBH A;  3E9S A;  3AI8 A;  1ZIV A;  3BCN A;  2AUZ A;  1VJV A;  4W5B A;  3QT4 A;  5CVO B;  3K24 A;  3K8U A;  1ME3 A;  2PAD A;  4G54 A;  3W30 A;  4PP2 E;  2DJG B;  4ZUX U;  2OUL A;  3BWK A;  2GHU A;  5CHT A;  2YJ2 A;  1JQP A;  1AU0 A;  1ME4 A;  4XZX A;  3U8E A;  2R9F A;  2C0Y A;  4PI3 A;  3N3K A;  2G6D A;  1X9Y A;  4FJC A;  5J94 A;  3MHS A;  3O0U A;  4I05 A;  4MM3 B;  2DC8 A;  2UZJ A;  1NB3 A;  5JH3 A;  1AU4 A;  3E1Z B;  4IUM A;  4MZS A;  4OW0 A;  4OVZ A;  2YJ9 A;  2CB5 A;  1AYV A;  1O0E A;  1U9V A;  1STF E;  2E00 A;  1F2C A;  3H6S A;  1BY8 A;  2IBI A;  1VSN A;  3CH2 X;  1ITO A;  3PT2 A;  1QMY A;  1TLO A;  1SP4 B;  4DMX A;  7PCK A;  3O1G A;  3RVW A;  1SNK A;  4RF0 A;  4RY2 A;  1Y08 A;  5PAD A;  3HWN A;  2CIO A;  4FK5 A;  1EWO A;  2R9O A;  2NQI A;  2DCB A;  1M6D A;  4OEM A;  3N4C A;  1CV8 A;  2NQD B;  2FE8 A;  4OVZ B;  2E03 A;  4MZO A;  4P6E A;  1YVB A;  2BTW A;  3MJ5 A;  3ERV A;  4X6I A;  5JZE A;  4XR7 A;  1TU6 A;  3HD3 A;  1AYW A;  4Q8H A;  4QRX A;  4K7C A;  1XKG A;  1EWL A;  4W5C A;  4CDF B;  1K3B B;  1CSB B;  2FT2 A;  1PIP A;  2BDL A;  2DJF B;  2FTD A;  4CZW A;  4A5U A;  1GLO A;  5A24 A;  3F5V A;  1BP4 A;  2HXZ A;  3KW9 A;  1POP A;  4WA6 A;  4I07 A;  4MI7 A;  3CBK A;  1HUC B;  1EWM A;  1NLJ A;  2ACT A;  3CBJ A;  3OIS A;  3PBH A;  3OF9 A;  2WBF X;  3PNR A;  6PAD A;  3KSE A;  3H8C A;  2BTW B;  1DKI A;  3TRK A;  4BOP A;  2P0R A;  1ATK A;  3PDF A;  2O6X A;  2R9C A;  1PE6 A;  4QRV A;  1DF0 A;  4XUI A;  3PRM A;  4R3D A;  3IV2 A;  5EZS A;  3K9M A;  2DCD A;  4MSX A;  4BOS A;  1ICF A;  2NQA A;  3BY4 A;  3NHE A;  1S4V A;  4YYU A;  1GEC E;  1YT7 A;  3DF0 A;  2AU1 A;  4QBB A;  1Q6K A;  3KX1 A;  2ATO A;  2OZ2 A;  3KFQ A;  4N79 A;  1UKF A;  2R9N A;  3PHW A;  4CDC B;  4N8W A;  2DC7 A;  8PCH A;  3PW3 A;  3ZUA A;  1KHQ A;  1U9W A;  2DC9 A;  2E01 A;  4RKX A;  4YYQ A;  4BOU A;  1NQC A;  2DZZ A;  3MTN A;  1PAD A;  5F02 A;  2DCA A;  1KHP A;  5KO3 A;  3KWZ A;  4KLB A;  1AU3 A;  1PCI A;  4PP1 A;  3RVV A;  1EF7 A;  1MS6 A;  3C9E A;  2XU3 A;  2R6N A;  9PAP A;  4IP3 A;  1BGO A;  2BU3 A;  2G8E A;  3O65 A;  1PPN A;  1CB5 A;  1PXV A;  3WXE A;  1YZB A;  3BBA A;  1CVZ A;  4X6H A;  3MP2 A;  3PHX A;  3N3G A;  1AEC A;  1QXP A;  2VHF A;  3RNV A;  3IHP A;  2HD5 A;  2H7J A;  2Z84 A;  3H8B A;  3LXS A;  3OF8 A;  1MDW A;  1MIR A;  1AIM A;  4BPV A;  4N4Z A;  2YJB A;  3BB7 A;  4PT5 A;  1CJL A;  2FQ9 A;  3PSE A;  2JTC A;  3S3R A;  2G7Y A;  2DZY A;  5E6J A;  2FRA A;  2FO5 A;  3GCB A;  4BOQ A;  3F75 A;  4BOZ A;  4M0W A;  1QDQ A;  4YYV A;  3IEJ A;  4FIP A;  4DMY A;  4HWY A;  4BQV A;  1ZCM A;  3BPF A;  3P5X A;  1YK8 A;  1KFU L;  3LFY A;  1CQD A;  2DOS A;  1MEM A;  4W4U A;  4YVA A;  2DC6 A;  3B21 A;  4Q8G A;  2AIM A;  2PRE A;  4D8B A;  1PVJ A;  1FH0 A;  3S3Q A;  1GCB A;  3P5W A;  1TL9 A;  2ARY A;  2FYE A;  4GUA A;  2B1M A;  3B79 A;  3RVX A;  2XU5 A;  5EF4 A;  4P16 A;  3OQC A;  2AVW A;  3IOQ A;  2BDZ A;  2XU1 A;  3HHI A;  2G8J A;  1NL6 A;  3MOR A;  1F2A A;  4D8E A;  2GFO A;  3IUT A;  2E02 A;  1YK7 A;  3IMA A;  1THE A;  2Y6E A;  5FPW A;  2J7Q A;  3TMP A;  1PPP A;  5EGW A;  2P7U A;  4BS5 A;  4RNA A;  2FUD A;  2YJ8 A;  1BQI A;  1AYU A;  2FRQ A;  1MEG A;  4AXM A;  1DEU A;  4BSQ A;  1PPO A;  1KFX L;  3M99 A;  3OVX A;  3W31 A;  2P86 A;  3QSD A;  3WXG A;  3D6S A;  2AUX A;  1PPD A;  2J7Q C;  4YYR A;  5CHV A;  2IPP B;  1GMY A;  3P5U A;  3USV A;  3PHU A;  3WXF A;  1IWD A;  1Y4H A;  3H89 A;  2VHS A;  2R9M A;  2JRI A;  1QOL A;  4BS6 A;  3QJ3 A;  2PBH A;  1EWP A;  1U9Q X;  3P5V A;  2HH5 A;  1MHW A;  3BPM A;  4QRG A;  3I06 A;  5JA7 A;  2DCC A;  2YJC A;  4HXD B;  3MTV A;  2AS8 A;  4D8I A;  3BOW A;  1NB5 A;  2XU4 A;  1YAL A;  1A6R A;  5CVM A; 
#chains in the Genus database with same CATH homology
 5CVN B;  1U9X A;  3KKU A;  2JQG R;  2F1G A;  1KXR A;  2NQG A;  3V6C A;  1W6F A;  4P6G A;  4X6J A;  1NPZ A;  4QH6 A;  5K16 A;  2AYN A;  2AYO A;  2OP3 A;  3KWB X;  3I3T A;  3OVZ A;  2JQF R;  2PNS A;  3MHH A;  3H7D A;  4CDE B;  3V6E A;  2Y5B A;  4YYS A;  3CH3 X;  4CDD B;  4YV8 A;  4YYW A;  1AU2 A;  2B1N A;  3TNX A;  1F29 A;  4OEL A;  2F7D A;  2HHN A;  1CTE A;  3BC3 A;  1CS8 A;  1CPJ A;  1F2B A;  4PAD A;  3HHA A;  1U5I A;  4I04 A;  4AXL A;  1PBH A;  3AI8 A;  1ZIV A;  3BCN A;  2AUZ A;  1VJV A;  4W5B A;  3QT4 A;  5CVO B;  3K24 A;  3K8U A;  1ME3 A;  2PAD A;  4G54 A;  4PP2 E;  2DJG B;  4ZUX U;  2OUL A;  3BWK A;  2GHU A;  5CHT A;  2YJ2 A;  1JQP A;  1AU0 A;  1ME4 A;  3U8E A;  2R9F A;  2C0Y A;  4PI3 A;  1W4T A;  3N3K A;  2G6D A;  1X9Y A;  4FJC A;  5J94 A;  3MHS A;  3O0U A;  4I05 A;  2VFB A;  2DC8 A;  1NB3 A;  5JH3 A;  1AU4 A;  3E1Z B;  4MZS A;  2YJ9 A;  2CB5 A;  1AYV A;  1O0E A;  1U9V A;  1STF E;  2E00 A;  1F2C A;  3H6S A;  1BY8 A;  2IBI A;  1VSN A;  3CH2 X;  1ITO A;  1QMY A;  1TLO A;  1SP4 B;  4DMX A;  7PCK A;  3O1G A;  3RVW A;  1SNK A;  4RY2 A;  1Y08 A;  5PAD A;  3HWN A;  2CIO A;  4FK5 A;  1EWO A;  2R9O A;  2NQI A;  2DCB A;  1M6D A;  4OEM A;  3N4C A;  1CV8 A;  2BSZ A;  2NQD B;  2E03 A;  4MZO A;  4P6E A;  1YVB A;  4X6I A;  3ERV A;  4XR7 A;  1TU6 A;  3HD3 A;  1AYW A;  4Q8H A;  4QRX A;  4K7C A;  1XKG A;  1EWL A;  4W5C A;  4CDF B;  1K3B B;  1CSB B;  2FT2 A;  1PIP A;  2BDL A;  2DJF B;  2FTD A;  4CZW A;  1GLO A;  5A24 A;  3F5V A;  1BP4 A;  2HXZ A;  3KW9 A;  1POP A;  4WA6 A;  4I07 A;  3CBK A;  1HUC B;  1EWM A;  1NLJ A;  2ACT A;  3CBJ A;  3OIS A;  3PBH A;  3OF9 A;  2WBF X;  1E2T A;  3PNR A;  6PAD A;  3KSE A;  3H8C A;  2P0R A;  1ATK A;  3PDF A;  2O6X A;  2R9C A;  1PE6 A;  4QRV A;  1DF0 A;  4XUI A;  3IV2 A;  3K9M A;  2DCD A;  4MSX A;  1ICF A;  2NQA A;  3NHE A;  1S4V A;  4YYU A;  1GEC E;  1YT7 A;  3DF0 A;  2AU1 A;  4QBB A;  1Q6K A;  3KX1 A;  2ATO A;  2OZ2 A;  3KFQ A;  4NV7 A;  4N79 A;  2R9N A;  4CDC B;  4N8W A;  2DC7 A;  8PCH A;  3PW3 A;  3ZUA A;  1KHQ A;  1U9W A;  2DC9 A;  2E01 A;  4YYQ A;  1NQC A;  2DZZ A;  3MTN A;  1PAD A;  5F02 A;  4GUZ A;  2DCA A;  1KHP A;  3KWZ A;  4KLB A;  1AU3 A;  1PCI A;  4PP1 A;  3RVV A;  1EF7 A;  1MS6 A;  3C9E A;  2XU3 A;  2R6N A;  9PAP A;  1BGO A;  2G8E A;  1PPN A;  1CB5 A;  1PXV A;  3WXE A;  1CVZ A;  4X6H A;  3N3G A;  1AEC A;  1QXP A;  2VHF A;  3IHP A;  2HD5 A;  2H7J A;  3H8B A;  3LXS A;  3OF8 A;  1MDW A;  1MIR A;  1AIM A;  4BPV A;  4N4Z A;  2YJB A;  1CJL A;  3D9W A;  2FQ9 A;  3LTW A;  3S3R A;  2G7Y A;  2DZY A;  2FRA A;  2FO5 A;  3GCB A;  3F75 A;  1QDQ A;  4YYV A;  3IEJ A;  4FIP A;  2VFC A;  4DMY A;  4HWY A;  4BQV A;  1ZCM A;  3BPF A;  4NV8 A;  3P5X A;  1YK8 A;  1KFU L;  3LFY A;  1CQD A;  1MEM A;  4W4U A;  4YVA A;  2DC6 A;  4Q8G A;  2AIM A;  2PRE A;  4C5P A;  1FH0 A;  3S3Q A;  1GCB A;  3P5W A;  1TL9 A;  2ARY A;  2FYE A;  2B1M A;  3B79 A;  3RVX A;  4BGF A;  2XU5 A;  5EF4 A;  4B55 A;  2AVW A;  3IOQ A;  2BDZ A;  2XU1 A;  3HHI A;  2G8J A;  1NL6 A;  3MOR A;  1F2A A;  2GFO A;  3IUT A;  2E02 A;  1YK7 A;  3IMA A;  1THE A;  2Y6E A;  5FPW A;  1PPP A;  5EGW A;  2P7U A;  4BS5 A;  2FUD A;  2YJ8 A;  1BQI A;  1AYU A;  2FRQ A;  1MEG A;  4AXM A;  1DEU A;  4BSQ A;  1PPO A;  1KFX L;  3M99 A;  3OVX A;  2P86 A;  3QSD A;  3WXG A;  1W5R A;  3D6S A;  2AUX A;  1PPD A;  4YYR A;  5CHV A;  2IPP B;  1GMY A;  3P5U A;  3USV A;  3WXF A;  1IWD A;  1Y4H A;  3H89 A;  2VHS A;  2R9M A;  1QOL A;  4BS6 A;  3QJ3 A;  2PBH A;  1EWP A;  1U9Q X;  3P5V A;  2HH5 A;  1MHW A;  3BPM A;  4QRG A;  1GX3 A;  3I06 A;  5JA7 A;  2DCC A;  2YJC A;  2AS8 A;  3BOW A;  1NB5 A;  2XU4 A;  1YAL A;  1A6R A;  5CVM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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