2NQDB

Crystal structure of cysteine protease inhibitor, chagasin, in complex with human cathepsin l
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
221
structure length
221
Chain Sequence
EAPRSVDWREKGYVTPVKNQGQCGSAWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the parasite protease inhibitor chagasin in complex with a host target cysteine protease
pubmed doi rcsb
molecule tags Hydrolase inhibitor/hydrolase
source organism Trypanosoma cruzi
molecule keywords Chagasin
total genus 72
structure length 221
sequence length 221
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2006-10-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2nqdB00
2DC8A 1SNKA 4AXLA 2DCCA 3RVWA 4FJCA 4OELA 3PBHA 1AECA 2ATOA 1X9YA 2OULA 3H6SA 2G6DA 2AYOA 1U9WA 3H8BA 2AUXA 1U5IA 1F29A 3K24A 3HD3A 4CDCB 1STFE 1GMYA 4QBBA 1CQDA 3KKUA 3MORA 4KLBA 5CVOB 4MZOA 2AVWA 1BQIA 4QRVA 3C9EA 4FK5A 4YYQA 1NL6A 5CVNB 2DC6A 2ARYA 2CIOA 4YYVA 3IMAA 1AIMA 2F1GA 4YVAA 1AU3A 1CTEA 4BSQA 2NQAA 4P6GA 2XU4A 3KSEA 1TU6A 3M99A 3KWZA 1EWPA 6PADA 2ACTA 1YVBA 3H8CA 4I05A 2FO5A 4PP1A 4I07A 1U9XA 4RY2A 1ITOA 1F2CA 3CBJA 3CBKA 1BP4A 2OP3A 2E03A 1EWOA 1PCIA 1MEMA 1A6RA 1MS6A 2NQGA 1DEUA 4K7CA 1F2AA 3V6CA 2GFOA 2HD5A 4AXMA 2DC9A 1AYUA 2B1NA 3DF0A 2DZYA 1CS8A 2VHFA 2WBFX 3V6EA 3E1ZB 2CB5A 4CZWA 5FPWA 4DMYA 1PXVA 1XKGA 4W5BA 4X6IA 1KHPA 4YYRA 2AUZA 4CDFB 2JQFR 3K8UA 2FTDA 1NPZA 1PPDA 2C0YA 3TNXA 2GHUA 2G8EA 2YJBA 3H89A 2DCAA 2VHSA 3N4CA 2NQIA 3IEJA 1HUCB 2YJ8A 3WXGA 4I04A 4FIPA 4Q8HA 5CVMA 2G8JA 4BS5A 1YK8A 4W5CA 2R9CA 1POPA 1CJLA 3KFQA 3S3RA 2P0RA 3BOWA 3MHHA 1JQPA 4QRGA 1PPNA 5PADA 2PREA 3CH2X 2FRAA 4XUIA 1ATKA 1VJVA 5A24A 3F5VA 2BDZA 3AI8A 3IV2A 2AU1A 1PADA 1QXPA 1QDQA 3RVXA 3U8EA 1Y08A 1PBHA 1MIRA 3NHEA 2R9OA 4YV8A 1NB5A 5CHTA 4PP2E 5CHVA 1O0EA 2G7YA 2P7UA 1ZCMA 2O6XA 2IBIA 1Q6KA 3P5WA 1VSNA 2PNSA 1DF0A 1EF7A 4BPVA 2BDLA 1BY8A 2H7JA 1AU0A 3MHSA 4OEMA 2PADA 4W4UA 3H7DA 3KX1A 1KHQA 1U9QX 1YK7A 2HXZA 1KFUL 3I06A 1EWLA 2DC7A 2P86A 1YT7A 3RVVA 1CVZA 1ME4A 4WA6A 2FT2A 3QJ3A 3O0UA 2YJ2A 2FRQA 4QRXA 3P5VA 4N8WA 1AU4A 3I3TA 3BWKA 7PCKA 3F75A 1ICFA 2E00A 1EWMA 2Y6EA 4CDEB 1Y4HA 1U9VA 2FUDA 2E02A 1GCBA 1YALA 4N79A 5EGWA 4BS6A 1F2BA 1M6DA 2DCDA 3K9MA 3QSDA 4YYSA 3PW3A 1CSBB 1AYVA 1PIPA 2NQDB 9PAPA 2B1MA 3OF9A 3OVXA 4Q8GA 2DJGB 3IUTA 1ME3A 3D6SA 2R9NA 4HWYA 1TLOA 8PCHA 1THEA 2IPPB 1SP4B 1BGOA 3S3QA 2DJFB 3ERVA 1PE6A 4N4ZA 3OISA 4YYWA 1GLOA 1MDWA 1CB5A 3GCBA 3PDFA 4QH6A 5JA7A 2HHNA 3N3KA 2XU3A 2YJCA 2YJ9A 2FQ9A 3HWNA 5EF4A 4MZSA 2OZ2A 1CV8A 3P5UA 3BCNA 2HH5A 3HHIA 5F02A 1IWDA 1AU2A 2DZZA 2R9FA 4BQVA 2XU5A 2F7DA 3KWBX 1GECE 2JQGR 4X6JA 3OVZA 3WXEA 2Y5BA 1MHWA 1QOLA 4G54A 3USVA 4MSXA 1K3BB 2FYEA 1NB3A 3PNRA 4YYUA 3BC3A 1MEGA 3KW9A 1NLJA 4CDDB 2R9MA 3OF8A 4ZUXU 3IOQA 1AYWA 2XU1A 1FH0A 3QT4A 1CPJA 1TL9A 3MTNA 5K16A 1NQCA 1PPPA 2AS8A 4XR7A 3LFYA 1ZIVA 4P6EA 1KXRA 2AYNA 3BPMA 2E01A 3LXSA 1QMYA 3P5XA 3IHPA 3N3GA 3O1GA 3WXFA 4PADA 4DMXA 2DCBA 1KFXL 1PPOA 4PI3A 2R6NA 2AIMA 3HHAA 4X6HA 5J94A 3BPFA 1S4VA 2PBHA 3ZUAA 5JH3A 3CH3X 3B79A
chains in the Genus database with same CATH superfamily
2DC8A 1SNKA 4AXLA 2DCCA 3RVWA 4FJCA 4OELA 3PBHA 1AECA 2ATOA 1X9YA 2OULA 3H6SA 2G6DA 2AYOA 1U9WA 3H8BA 4M0WA 2AUXA 1U5IA 1F29A 3K24A 3HD3A 4CDCB 1STFE 1GMYA 4QBBA 2HWKA 1CQDA 3KKUA 3MORA 4KLBA 5CVOB 4MZOA 2AVWA 1BQIA 1DKIA 4QRVA 3C9EA 4FK5A 4YYQA 1NL6A 5CVNB 2DC6A 2ARYA 2CIOA 4YYVA 3IMAA 1AIMA 3RNVA 2F1GA 4YVAA 1AU3A 1CTEA 3BY4A 4BSQA 2NQAA 4P6GA 2XU4A 3KSEA 1TU6A 3M99A 3KWZA 1EWPA 6PADA 2ACTA 3OQCA 1YVBA 3H8CA 4I05A 2FO5A 4PP1A 4I07A 1U9XA 4RY2A 1ITOA 3B21A 1F2CA 3CBJA 3CBKA 1BP4A 2OP3A 4RKXA 2E03A 1EWOA 1PCIA 1MEMA 5KO3A 1A6RA 4ZTBA 1MS6A 2NQGA 1DEUA 4K7CA 1F2AA 3V6CA 2GFOA 2HD5A 4REZA 4AXMA 2DC9A 1AYUA 2B1NA 3DF0A 2DZYA 1CS8A 2VHFA 2WBFX 5E6JA 3V6EA 3E1ZB 2CB5A 3IFUA 4CZWA 5FPWA 4DMYA 2JTCA 1PXVA 2J7QC 1XKGA 4W5BA 4GUAA 4X6IA 1KHPA 4YYRA 2AUZA 4CDFB 2JQFR 3K8UA 2FTDA 1NPZA 1PPDA 2C0YA 3TNXA 2GHUA 2G8EA 3MP2A 2YJBA 3H89A 2DCAA 2VHSA 3N4CA 2NQIA 3IEJA 1HUCB 2YJ8A 3WXGA 4I04A 3PHXA 4FIPA 4Q8HA 5CVMA 2G8JA 4BS5A 1YK8A 4W5CA 2R9CA 1POPA 4P16A 3ZNHA 1CJLA 3KFQA 3S3RA 2P0RA 3BOWA 3MHHA 4IP3A 1JQPA 4QRGA 1PPNA 5PADA 4BOPA 2PREA 3CH2X 4HXDB 2FRAA 4R3DA 4XUIA 1ATKA 1VJVA 5A24A 3F5VA 4D8EA 2BDZA 4PT5A 3MJ5A 3AI8A 3IV2A 2AU1A 1PADA 4A5UA 1QXPA 1QDQA 3PSEA 3RVXA 3U8EA 1Y08A 1PBHA 1MIRA 3NHEA 2BTWB 4BOUA 2R9OA 4YV8A 1NB5A 5CHTA 5EZQA 4PP2E 5CHVA 1O0EA 2G7YA 5JZEA 4MM3B 2P7UA 1ZCMA 2O6XA 2IBIA 1Q6KA 3P5WA 1VSNA 2PNSA 4OW0A 1DF0A 1EF7A 4BPVA 2BDLA 1BY8A 2H7JA 1AU0A 3MHSA 4OEMA 2PADA 4W4UA 3H7DA 3KX1A 1KHQA 1U9QX 1YK7A 2HXZA 1KFUL 3I06A 1EWLA 2DC7A 2P86A 1YT7A 3RVVA 1CVZA 3W31A 4IUMA 1ME4A 4WA6A 2FT2A 3QJ3A 3O0UA 2YJ2A 2FRQA 4QRXA 3O65A 1UKFA 3P5VA 4N8WA 1AU4A 3I3TA 3BWKA 7PCKA 3F75A 3MTVA 1ICFA 2E00A 1EWMA 2Y6EA 4CDEB 2Z84A 1Y4HA 1U9VA 4BOQA 2FUDA 2E02A 1GCBA 1YALA 4N79A 4RF1A 5EGWA 4BS6A 1F2BA 1M6DA 2DCDA 3K9MA 3QSDA 4YYSA 3PW3A 1CSBB 1AYVA 1PIPA 2NQDB 9PAPA 2B1MA 3OF9A 2DOSA 3OVXA 4Q8GA 3PRMA 2DJGB 3IUTA 4WURA 1ME3A 3PHWA 3TMPA 3D6SA 2R9NA 3BB7A 4HWYA 1TLOA 8PCHA 1THEA 2IPPB 1SP4B 1BGOA 3S3QA 2DJFB 3ERVA 3C0RA 2BU3A 1PE6A 4N4ZA 4OVZB 3OISA 4YYWA 2BTWA 4MI7A 4D8BA 3TRKA 1GLOA 4RNAA 1MDWA 1CB5A 3GCBA 3PDFA 3PHUA 4QH6A 5JA7A 2HHNA 3N3KA 2XU3A 2YJCA 3E9SA 2YJ9A 3W30A 5EZSA 4BOZA 2FQ9A 3HWNA 5EF4A 4MZSA 2OZ2A 1CV8A 4RF0A 3P5UA 3BCNA 2FE8A 2J7QA 3PRPA 2HH5A 3HHIA 3BBAA 1IWDA 5F02A 1AU2A 2DZZA 2R9FA 4D8IA 4BQVA 2XU5A 3PT2A 2F7DA 3KWBX 1GECE 2JQGR 4X6JA 3OVZA 3WXEA 2Y5BA 1MHWA 1QOLA 4G54A 3USVA 1PVJA 4MSXA 1K3BB 2FYEA 1NB3A 3PNRA 4YYUA 3BC3A 1MEGA 3KW9A 1NLJA 4CDDB 2R9MA 3OF8A 4ZUXU 3IOQA 1AYWA 2UZJA 2XU1A 1FH0A 3QT4A 4BOSA 1CPJA 1TL9A 3MTNA 5K16A 1NQCA 1PPPA 2AS8A 4XR7A 2JRIA 3LFYA 1ZIVA 2AGAA 4P6EA 1KXRA 2AYNA 3BPMA 2E01A 3LXSA 1YZBA 1QMYA 3P5XA 3IHPA 3N3GA 3O1GA 3WXFA 4PADA 4DMXA 2DCBA 4OVZA 1KFXL 1PPOA 4XZXA 4PI3A 2R6NA 2AIMA 3HHAA 4X6HA 5J94A 3BPFA 1S4VA 2PBHA 3ZUAA 5JH3A 3CH3X 3B79A
chains in the Genus database with same CATH topology
2DC8A 1SNKA 4AXLA 2DCCA 3RVWA 4FJCA 4OELA 3PBHA 1AECA 2ATOA 1X9YA 2OULA 3H6SA 2G6DA 2AYOA 1U9WA 3H8BA 2AUXA 1U5IA 1F29A 3K24A 3HD3A 4CDCB 1STFE 1GMYA 4QBBA 1CQDA 3KKUA 3MORA 4KLBA 5CVOB 4MZOA 2AVWA 1BQIA 4QRVA 3C9EA 4FK5A 3LTWA 4YYQA 1NL6A 5CVNB 2DC6A 2ARYA 2CIOA 4YYVA 3IMAA 1AIMA 2F1GA 4YVAA 1AU3A 1CTEA 4BSQA 2NQAA 4P6GA 2XU4A 3KSEA 1TU6A 3M99A 3KWZA 1EWPA 6PADA 2ACTA 1YVBA 3H8CA 4I05A 2FO5A 4PP1A 4I07A 1U9XA 4RY2A 1ITOA 1F2CA 3CBJA 3CBKA 1BP4A 2OP3A 2E03A 1EWOA 1PCIA 1MEMA 1A6RA 1MS6A 2NQGA 1GX3A 1DEUA 4K7CA 4GUZA 1F2AA 3V6CA 2GFOA 2HD5A 4AXMA 4NV8A 2DC9A 1AYUA 2B1NA 3DF0A 1W5RA 2DZYA 1CS8A 2VHFA 2WBFX 3V6EA 3E1ZB 2CB5A 4CZWA 5FPWA 4DMYA 1PXVA 2VFCA 1XKGA 4W5BA 4X6IA 1KHPA 4YYRA 2AUZA 4CDFB 2JQFR 3K8UA 2FTDA 1NPZA 1PPDA 2C0YA 3TNXA 2GHUA 2G8EA 2YJBA 3H89A 2DCAA 2VHSA 3N4CA 2NQIA 3IEJA 4C5PA 1HUCB 2YJ8A 3WXGA 2VFBA 4I04A 4FIPA 4Q8HA 5CVMA 2G8JA 4BS5A 1YK8A 4W5CA 2R9CA 1POPA 1CJLA 3KFQA 3S3RA 2P0RA 3BOWA 3MHHA 1JQPA 4QRGA 1PPNA 5PADA 2PREA 3CH2X 2FRAA 4BGFA 4XUIA 1ATKA 1VJVA 5A24A 3F5VA 2BDZA 3AI8A 3IV2A 2AU1A 1PADA 1QXPA 1QDQA 3RVXA 3U8EA 1Y08A 1PBHA 1MIRA 3NHEA 2R9OA 4YV8A 1NB5A 5CHTA 4PP2E 5CHVA 1O0EA 2G7YA 2P7UA 1ZCMA 3D9WA 2O6XA 4B55A 2IBIA 1Q6KA 3P5WA 1VSNA 2PNSA 1DF0A 1EF7A 4BPVA 2BDLA 1BY8A 2H7JA 1AU0A 3MHSA 1W4TA 4OEMA 2PADA 4W4UA 3H7DA 3KX1A 1KHQA 1U9QX 1YK7A 2HXZA 1KFUL 3I06A 1EWLA 2DC7A 2P86A 1YT7A 3RVVA 1CVZA 1ME4A 4WA6A 2FT2A 3QJ3A 3O0UA 2YJ2A 2FRQA 4QRXA 3P5VA 4N8WA 1AU4A 3I3TA 3BWKA 7PCKA 3F75A 1ICFA 1E2TA 2E00A 1EWMA 2Y6EA 4CDEB 1Y4HA 1U9VA 2FUDA 2E02A 1GCBA 1YALA 4N79A 5EGWA 4BS6A 1F2BA 1M6DA 2DCDA 3K9MA 3QSDA 4YYSA 3PW3A 1CSBB 1AYVA 1PIPA 2NQDB 9PAPA 2B1MA 3OF9A 3OVXA 4Q8GA 2DJGB 3IUTA 1ME3A 4NV7A 3D6SA 2R9NA 4HWYA 1TLOA 8PCHA 1THEA 2IPPB 1SP4B 1BGOA 3S3QA 2DJFB 3ERVA 1PE6A 4N4ZA 3OISA 4YYWA 1GLOA 1MDWA 1CB5A 3GCBA 3PDFA 4QH6A 5JA7A 2HHNA 3N3KA 1W6FA 2XU3A 2YJCA 2YJ9A 2FQ9A 3HWNA 5EF4A 4MZSA 2OZ2A 1CV8A 3P5UA 3BCNA 2BSZA 2HH5A 3HHIA 5F02A 1IWDA 1AU2A 2DZZA 2R9FA 4BQVA 2XU5A 2F7DA 3KWBX 1GECE 2JQGR 4X6JA 3OVZA 3WXEA 2Y5BA 1MHWA 1QOLA 4G54A 3USVA 4MSXA 1K3BB 2FYEA 1NB3A 3PNRA 4YYUA 3BC3A 1MEGA 3KW9A 1NLJA 4CDDB 2R9MA 3OF8A 4ZUXU 3IOQA 1AYWA 2XU1A 1FH0A 3QT4A 1CPJA 1TL9A 3MTNA 5K16A 1NQCA 1PPPA 2AS8A 4XR7A 3LFYA 1ZIVA 4P6EA 1KXRA 2AYNA 3BPMA 2E01A 3LXSA 1QMYA 3P5XA 3IHPA 3N3GA 3O1GA 3WXFA 4PADA 4DMXA 2DCBA 1KFXL 1PPOA 4PI3A 2R6NA 2AIMA 3HHAA 4X6HA 5J94A 3BPFA 1S4VA 2PBHA 3ZUAA 5JH3A 3CH3X 3B79A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DC8 A;  1SNK A;  4AXL A;  2DCC A;  3RVW A;  4FJC A;  4OEL A;  3PBH A;  1AEC A;  2ATO A;  1X9Y A;  2OUL A;  3H6S A;  2G6D A;  2AYO A;  1U9W A;  3H8B A;  2AUX A;  1U5I A;  1F29 A;  3K24 A;  3HD3 A;  4CDC B;  1STF E;  1GMY A;  4QBB A;  1CQD A;  3KKU A;  3MOR A;  4KLB A;  5CVO B;  4MZO A;  2AVW A;  1BQI A;  4QRV A;  3C9E A;  4FK5 A;  4YYQ A;  1NL6 A;  5CVN B;  2DC6 A;  2ARY A;  2CIO A;  4YYV A;  3IMA A;  1AIM A;  2F1G A;  4YVA A;  1AU3 A;  1CTE A;  4BSQ A;  2NQA A;  4P6G A;  2XU4 A;  3KSE A;  1TU6 A;  3M99 A;  3KWZ A;  1EWP A;  6PAD A;  2ACT A;  1YVB A;  3H8C A;  4I05 A;  2FO5 A;  4PP1 A;  4I07 A;  1U9X A;  4RY2 A;  1ITO A;  1F2C A;  3CBJ A;  3CBK A;  1BP4 A;  2OP3 A;  2E03 A;  1EWO A;  1PCI A;  1MEM A;  1A6R A;  1MS6 A;  2NQG A;  1DEU A;  4K7C A;  1F2A A;  3V6C A;  2GFO A;  2HD5 A;  4AXM A;  2DC9 A;  1AYU A;  2B1N A;  3DF0 A;  2DZY A;  1CS8 A;  2VHF A;  2WBF X;  3V6E A;  3E1Z B;  2CB5 A;  4CZW A;  5FPW A;  4DMY A;  1PXV A;  1XKG A;  4W5B A;  4X6I A;  1KHP A;  4YYR A;  2AUZ A;  4CDF B;  2JQF R;  3K8U A;  2FTD A;  1NPZ A;  1PPD A;  2C0Y A;  3TNX A;  2GHU A;  2G8E A;  2YJB A;  3H89 A;  2DCA A;  2VHS A;  3N4C A;  2NQI A;  3IEJ A;  1HUC B;  2YJ8 A;  3WXG A;  4I04 A;  4FIP A;  4Q8H A;  5CVM A;  2G8J A;  4BS5 A;  1YK8 A;  4W5C A;  2R9C A;  1POP A;  1CJL A;  3KFQ A;  3S3R A;  2P0R A;  3BOW A;  3MHH A;  1JQP A;  4QRG A;  1PPN A;  5PAD A;  2PRE A;  3CH2 X;  2FRA A;  4XUI A;  1ATK A;  1VJV A;  5A24 A;  3F5V A;  2BDZ A;  3AI8 A;  3IV2 A;  2AU1 A;  1PAD A;  1QXP A;  1QDQ A;  3RVX A;  3U8E A;  1Y08 A;  1PBH A;  1MIR A;  3NHE A;  2R9O A;  4YV8 A;  1NB5 A;  5CHT A;  4PP2 E;  5CHV A;  1O0E A;  2G7Y A;  2P7U A;  1ZCM A;  2O6X A;  2IBI A;  1Q6K A;  3P5W A;  1VSN A;  2PNS A;  1DF0 A;  1EF7 A;  4BPV A;  2BDL A;  1BY8 A;  2H7J A;  1AU0 A;  3MHS A;  4OEM A;  2PAD A;  4W4U A;  3H7D A;  3KX1 A;  1KHQ A;  1U9Q X;  1YK7 A;  2HXZ A;  1KFU L;  3I06 A;  1EWL A;  2DC7 A;  2P86 A;  1YT7 A;  3RVV A;  1CVZ A;  1ME4 A;  4WA6 A;  2FT2 A;  3QJ3 A;  3O0U A;  2YJ2 A;  2FRQ A;  4QRX A;  3P5V A;  4N8W A;  1AU4 A;  3I3T A;  3BWK A;  7PCK A;  3F75 A;  1ICF A;  2E00 A;  1EWM A;  2Y6E A;  4CDE B;  1Y4H A;  1U9V A;  2FUD A;  2E02 A;  1GCB A;  1YAL A;  4N79 A;  5EGW A;  4BS6 A;  1F2B A;  1M6D A;  2DCD A;  3K9M A;  3QSD A;  4YYS A;  3PW3 A;  1CSB B;  1AYV A;  1PIP A;  2NQD B;  9PAP A;  2B1M A;  3OF9 A;  3OVX A;  4Q8G A;  2DJG B;  3IUT A;  1ME3 A;  3D6S A;  2R9N A;  4HWY A;  1TLO A;  8PCH A;  1THE A;  2IPP B;  1SP4 B;  1BGO A;  3S3Q A;  2DJF B;  3ERV A;  1PE6 A;  4N4Z A;  3OIS A;  4YYW A;  1GLO A;  1MDW A;  1CB5 A;  3GCB A;  3PDF A;  4QH6 A;  5JA7 A;  2HHN A;  3N3K A;  2XU3 A;  2YJC A;  2YJ9 A;  2FQ9 A;  3HWN A;  5EF4 A;  4MZS A;  2OZ2 A;  1CV8 A;  3P5U A;  3BCN A;  2HH5 A;  3HHI A;  5F02 A;  1IWD A;  1AU2 A;  2DZZ A;  2R9F A;  4BQV A;  2XU5 A;  2F7D A;  3KWB X;  1GEC E;  2JQG R;  4X6J A;  3OVZ A;  3WXE A;  2Y5B A;  1MHW A;  1QOL A;  4G54 A;  3USV A;  4MSX A;  1K3B B;  2FYE A;  1NB3 A;  3PNR A;  4YYU A;  3BC3 A;  1MEG A;  3KW9 A;  1NLJ A;  4CDD B;  2R9M A;  3OF8 A;  4ZUX U;  3IOQ A;  1AYW A;  2XU1 A;  1FH0 A;  3QT4 A;  1CPJ A;  1TL9 A;  3MTN A;  5K16 A;  1NQC A;  1PPP A;  2AS8 A;  4XR7 A;  3LFY A;  1ZIV A;  4P6E A;  1KXR A;  2AYN A;  3BPM A;  2E01 A;  3LXS A;  1QMY A;  3P5X A;  3IHP A;  3N3G A;  3O1G A;  3WXF A;  4PAD A;  4DMX A;  2DCB A;  1KFX L;  1PPO A;  4PI3 A;  2R6N A;  2AIM A;  3HHA A;  4X6H A;  5J94 A;  3BPF A;  1S4V A;  2PBH A;  3ZUA A;  5JH3 A;  3CH3 X;  3B79 A; 
#chains in the Genus database with same CATH topology
 2DC8 A;  1SNK A;  4AXL A;  2DCC A;  3RVW A;  4FJC A;  4OEL A;  3PBH A;  1AEC A;  2ATO A;  1X9Y A;  2OUL A;  3H6S A;  2G6D A;  2AYO A;  1U9W A;  3H8B A;  4M0W A;  2AUX A;  1U5I A;  1F29 A;  3K24 A;  3HD3 A;  4CDC B;  1STF E;  1GMY A;  4QBB A;  2HWK A;  1CQD A;  3KKU A;  3MOR A;  4KLB A;  5CVO B;  4MZO A;  2AVW A;  1BQI A;  1DKI A;  4QRV A;  3C9E A;  4FK5 A;  4YYQ A;  1NL6 A;  5CVN B;  2DC6 A;  2ARY A;  2CIO A;  4YYV A;  3IMA A;  1AIM A;  3RNV A;  2F1G A;  4YVA A;  1AU3 A;  1CTE A;  3BY4 A;  4BSQ A;  2NQA A;  4P6G A;  2XU4 A;  3KSE A;  1TU6 A;  3M99 A;  3KWZ A;  1EWP A;  6PAD A;  2ACT A;  3OQC A;  1YVB A;  3H8C A;  4I05 A;  2FO5 A;  4PP1 A;  4I07 A;  1U9X A;  4RY2 A;  1ITO A;  3B21 A;  1F2C A;  3CBJ A;  3CBK A;  1BP4 A;  2OP3 A;  4RKX A;  2E03 A;  1EWO A;  1PCI A;  1MEM A;  5KO3 A;  1A6R A;  4ZTB A;  1MS6 A;  2NQG A;  1DEU A;  4K7C A;  1F2A A;  3V6C A;  2GFO A;  2HD5 A;  4REZ A;  4AXM A;  2DC9 A;  1AYU A;  2B1N A;  3DF0 A;  2DZY A;  1CS8 A;  2VHF A;  2WBF X;  5E6J A;  3V6E A;  3E1Z B;  2CB5 A;  3IFU A;  4CZW A;  5FPW A;  4DMY A;  2JTC A;  1PXV A;  2J7Q C;  1XKG A;  4W5B A;  4GUA A;  4X6I A;  1KHP A;  4YYR A;  2AUZ A;  4CDF B;  2JQF R;  3K8U A;  2FTD A;  1NPZ A;  1PPD A;  2C0Y A;  3TNX A;  2GHU A;  2G8E A;  3MP2 A;  2YJB A;  3H89 A;  2DCA A;  2VHS A;  3N4C A;  2NQI A;  3IEJ A;  1HUC B;  2YJ8 A;  3WXG A;  4I04 A;  3PHX A;  4FIP A;  4Q8H A;  5CVM A;  2G8J A;  4BS5 A;  1YK8 A;  4W5C A;  2R9C A;  1POP A;  4P16 A;  3ZNH A;  1CJL A;  3KFQ A;  3S3R A;  2P0R A;  3BOW A;  3MHH A;  4IP3 A;  1JQP A;  4QRG A;  1PPN A;  5PAD A;  4BOP A;  2PRE A;  3CH2 X;  4HXD B;  2FRA A;  4R3D A;  4XUI A;  1ATK A;  1VJV A;  5A24 A;  3F5V A;  4D8E A;  2BDZ A;  4PT5 A;  3MJ5 A;  3AI8 A;  3IV2 A;  2AU1 A;  1PAD A;  4A5U A;  1QXP A;  1QDQ A;  3PSE A;  3RVX A;  3U8E A;  1Y08 A;  1PBH A;  1MIR A;  3NHE A;  2BTW B;  4BOU A;  2R9O A;  4YV8 A;  1NB5 A;  5CHT A;  5EZQ A;  4PP2 E;  5CHV A;  1O0E A;  2G7Y A;  5JZE A;  4MM3 B;  2P7U A;  1ZCM A;  2O6X A;  2IBI A;  1Q6K A;  3P5W A;  1VSN A;  2PNS A;  4OW0 A;  1DF0 A;  1EF7 A;  4BPV A;  2BDL A;  1BY8 A;  2H7J A;  1AU0 A;  3MHS A;  4OEM A;  2PAD A;  4W4U A;  3H7D A;  3KX1 A;  1KHQ A;  1U9Q X;  1YK7 A;  2HXZ A;  1KFU L;  3I06 A;  1EWL A;  2DC7 A;  2P86 A;  1YT7 A;  3RVV A;  1CVZ A;  3W31 A;  4IUM A;  1ME4 A;  4WA6 A;  2FT2 A;  3QJ3 A;  3O0U A;  2YJ2 A;  2FRQ A;  4QRX A;  3O65 A;  1UKF A;  3P5V A;  4N8W A;  1AU4 A;  3I3T A;  3BWK A;  7PCK A;  3F75 A;  3MTV A;  1ICF A;  2E00 A;  1EWM A;  2Y6E A;  4CDE B;  2Z84 A;  1Y4H A;  1U9V A;  4BOQ A;  2FUD A;  2E02 A;  1GCB A;  1YAL A;  4N79 A;  4RF1 A;  5EGW A;  4BS6 A;  1F2B A;  1M6D A;  2DCD A;  3K9M A;  3QSD A;  4YYS A;  3PW3 A;  1CSB B;  1AYV A;  1PIP A;  2NQD B;  9PAP A;  2B1M A;  3OF9 A;  2DOS A;  3OVX A;  4Q8G A;  3PRM A;  2DJG B;  3IUT A;  4WUR A;  1ME3 A;  3PHW A;  3TMP A;  3D6S A;  2R9N A;  3BB7 A;  4HWY A;  1TLO A;  8PCH A;  1THE A;  2IPP B;  1SP4 B;  1BGO A;  3S3Q A;  2DJF B;  3ERV A;  3C0R A;  2BU3 A;  1PE6 A;  4N4Z A;  4OVZ B;  3OIS A;  4YYW A;  2BTW A;  4MI7 A;  4D8B A;  3TRK A;  1GLO A;  4RNA A;  1MDW A;  1CB5 A;  3GCB A;  3PDF A;  3PHU A;  4QH6 A;  5JA7 A;  2HHN A;  3N3K A;  2XU3 A;  2YJC A;  3E9S A;  2YJ9 A;  3W30 A;  5EZS A;  4BOZ A;  2FQ9 A;  3HWN A;  5EF4 A;  4MZS A;  2OZ2 A;  1CV8 A;  4RF0 A;  3P5U A;  3BCN A;  2FE8 A;  2J7Q A;  3PRP A;  2HH5 A;  3HHI A;  3BBA A;  1IWD A;  5F02 A;  1AU2 A;  2DZZ A;  2R9F A;  4D8I A;  4BQV A;  2XU5 A;  3PT2 A;  2F7D A;  3KWB X;  1GEC E;  2JQG R;  4X6J A;  3OVZ A;  3WXE A;  2Y5B A;  1MHW A;  1QOL A;  4G54 A;  3USV A;  1PVJ A;  4MSX A;  1K3B B;  2FYE A;  1NB3 A;  3PNR A;  4YYU A;  3BC3 A;  1MEG A;  3KW9 A;  1NLJ A;  4CDD B;  2R9M A;  3OF8 A;  4ZUX U;  3IOQ A;  1AYW A;  2UZJ A;  2XU1 A;  1FH0 A;  3QT4 A;  4BOS A;  1CPJ A;  1TL9 A;  3MTN A;  5K16 A;  1NQC A;  1PPP A;  2AS8 A;  4XR7 A;  2JRI A;  3LFY A;  1ZIV A;  2AGA A;  4P6E A;  1KXR A;  2AYN A;  3BPM A;  2E01 A;  3LXS A;  1YZB A;  1QMY A;  3P5X A;  3IHP A;  3N3G A;  3O1G A;  3WXF A;  4PAD A;  4DMX A;  2DCB A;  4OVZ A;  1KFX L;  1PPO A;  4XZX A;  4PI3 A;  2R6N A;  2AIM A;  3HHA A;  4X6H A;  5J94 A;  3BPF A;  1S4V A;  2PBH A;  3ZUA A;  5JH3 A;  3CH3 X;  3B79 A; 
#chains in the Genus database with same CATH homology
 2DC8 A;  1SNK A;  4AXL A;  2DCC A;  3RVW A;  4FJC A;  4OEL A;  3PBH A;  1AEC A;  2ATO A;  1X9Y A;  2OUL A;  3H6S A;  2G6D A;  2AYO A;  1U9W A;  3H8B A;  2AUX A;  1U5I A;  1F29 A;  3K24 A;  3HD3 A;  4CDC B;  1STF E;  1GMY A;  4QBB A;  1CQD A;  3KKU A;  3MOR A;  4KLB A;  5CVO B;  4MZO A;  2AVW A;  1BQI A;  4QRV A;  3C9E A;  4FK5 A;  3LTW A;  4YYQ A;  1NL6 A;  5CVN B;  2DC6 A;  2ARY A;  2CIO A;  4YYV A;  3IMA A;  1AIM A;  2F1G A;  4YVA A;  1AU3 A;  1CTE A;  4BSQ A;  2NQA A;  4P6G A;  2XU4 A;  3KSE A;  1TU6 A;  3M99 A;  3KWZ A;  1EWP A;  6PAD A;  2ACT A;  1YVB A;  3H8C A;  4I05 A;  2FO5 A;  4PP1 A;  4I07 A;  1U9X A;  4RY2 A;  1ITO A;  1F2C A;  3CBJ A;  3CBK A;  1BP4 A;  2OP3 A;  2E03 A;  1EWO A;  1PCI A;  1MEM A;  1A6R A;  1MS6 A;  2NQG A;  1GX3 A;  1DEU A;  4K7C A;  4GUZ A;  1F2A A;  3V6C A;  2GFO A;  2HD5 A;  4AXM A;  4NV8 A;  2DC9 A;  1AYU A;  2B1N A;  3DF0 A;  1W5R A;  2DZY A;  1CS8 A;  2VHF A;  2WBF X;  3V6E A;  3E1Z B;  2CB5 A;  4CZW A;  5FPW A;  4DMY A;  1PXV A;  2VFC A;  1XKG A;  4W5B A;  4X6I A;  1KHP A;  4YYR A;  2AUZ A;  4CDF B;  2JQF R;  3K8U A;  2FTD A;  1NPZ A;  1PPD A;  2C0Y A;  3TNX A;  2GHU A;  2G8E A;  2YJB A;  3H89 A;  2DCA A;  2VHS A;  3N4C A;  2NQI A;  3IEJ A;  4C5P A;  1HUC B;  2YJ8 A;  3WXG A;  2VFB A;  4I04 A;  4FIP A;  4Q8H A;  5CVM A;  2G8J A;  4BS5 A;  1YK8 A;  4W5C A;  2R9C A;  1POP A;  1CJL A;  3KFQ A;  3S3R A;  2P0R A;  3BOW A;  3MHH A;  1JQP A;  4QRG A;  1PPN A;  5PAD A;  2PRE A;  3CH2 X;  2FRA A;  4BGF A;  4XUI A;  1ATK A;  1VJV A;  5A24 A;  3F5V A;  2BDZ A;  3AI8 A;  3IV2 A;  2AU1 A;  1PAD A;  1QXP A;  1QDQ A;  3RVX A;  3U8E A;  1Y08 A;  1PBH A;  1MIR A;  3NHE A;  2R9O A;  4YV8 A;  1NB5 A;  5CHT A;  4PP2 E;  5CHV A;  1O0E A;  2G7Y A;  2P7U A;  1ZCM A;  3D9W A;  2O6X A;  4B55 A;  2IBI A;  1Q6K A;  3P5W A;  1VSN A;  2PNS A;  1DF0 A;  1EF7 A;  4BPV A;  2BDL A;  1BY8 A;  2H7J A;  1AU0 A;  3MHS A;  1W4T A;  4OEM A;  2PAD A;  4W4U A;  3H7D A;  3KX1 A;  1KHQ A;  1U9Q X;  1YK7 A;  2HXZ A;  1KFU L;  3I06 A;  1EWL A;  2DC7 A;  2P86 A;  1YT7 A;  3RVV A;  1CVZ A;  1ME4 A;  4WA6 A;  2FT2 A;  3QJ3 A;  3O0U A;  2YJ2 A;  2FRQ A;  4QRX A;  3P5V A;  4N8W A;  1AU4 A;  3I3T A;  3BWK A;  7PCK A;  3F75 A;  1ICF A;  1E2T A;  2E00 A;  1EWM A;  2Y6E A;  4CDE B;  1Y4H A;  1U9V A;  2FUD A;  2E02 A;  1GCB A;  1YAL A;  4N79 A;  5EGW A;  4BS6 A;  1F2B A;  1M6D A;  2DCD A;  3K9M A;  3QSD A;  4YYS A;  3PW3 A;  1CSB B;  1AYV A;  1PIP A;  2NQD B;  9PAP A;  2B1M A;  3OF9 A;  3OVX A;  4Q8G A;  2DJG B;  3IUT A;  1ME3 A;  4NV7 A;  3D6S A;  2R9N A;  4HWY A;  1TLO A;  8PCH A;  1THE A;  2IPP B;  1SP4 B;  1BGO A;  3S3Q A;  2DJF B;  3ERV A;  1PE6 A;  4N4Z A;  3OIS A;  4YYW A;  1GLO A;  1MDW A;  1CB5 A;  3GCB A;  3PDF A;  4QH6 A;  5JA7 A;  2HHN A;  3N3K A;  1W6F A;  2XU3 A;  2YJC A;  2YJ9 A;  2FQ9 A;  3HWN A;  5EF4 A;  4MZS A;  2OZ2 A;  1CV8 A;  3P5U A;  3BCN A;  2BSZ A;  2HH5 A;  3HHI A;  5F02 A;  1IWD A;  1AU2 A;  2DZZ A;  2R9F A;  4BQV A;  2XU5 A;  2F7D A;  3KWB X;  1GEC E;  2JQG R;  4X6J A;  3OVZ A;  3WXE A;  2Y5B A;  1MHW A;  1QOL A;  4G54 A;  3USV A;  4MSX A;  1K3B B;  2FYE A;  1NB3 A;  3PNR A;  4YYU A;  3BC3 A;  1MEG A;  3KW9 A;  1NLJ A;  4CDD B;  2R9M A;  3OF8 A;  4ZUX U;  3IOQ A;  1AYW A;  2XU1 A;  1FH0 A;  3QT4 A;  1CPJ A;  1TL9 A;  3MTN A;  5K16 A;  1NQC A;  1PPP A;  2AS8 A;  4XR7 A;  3LFY A;  1ZIV A;  4P6E A;  1KXR A;  2AYN A;  3BPM A;  2E01 A;  3LXS A;  1QMY A;  3P5X A;  3IHP A;  3N3G A;  3O1G A;  3WXF A;  4PAD A;  4DMX A;  2DCB A;  1KFX L;  1PPO A;  4PI3 A;  2R6N A;  2AIM A;  3HHA A;  4X6H A;  5J94 A;  3BPF A;  1S4V A;  2PBH A;  3ZUA A;  5JH3 A;  3CH3 X;  3B79 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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