2NQDB

Crystal structure of cysteine protease inhibitor, chagasin, in complex with human cathepsin l
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
221
structure length
221
Chain Sequence
EAPRSVDWREKGYVTPVKNQGQCGSAWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase inhibitor/hydrolase
molecule keywords Chagasin
publication title Crystal structure of the parasite protease inhibitor chagasin in complex with a host target cysteine protease
pubmed doi rcsb
source organism Trypanosoma cruzi
total genus 72
structure length 221
sequence length 221
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2006-10-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2nqdB00
2E00A 1QDQA 1TL9A 1AU2A 1QOLA 4QRVA 3PW3A 1U5IA 1F2CA 3OVZA 4FK5A 1K3BB 3AI8A 3NHEA 1CV8A 4PADA 1Q6KA 3S3QA 2XU1A 3KWBX 4DMXA 2E02A 1S4VA 2F7DA 2AS8A 2ARYA 1EWPA 1JQPA 4N8WA 4PI3A 2YJ9A 2DZYA 4CDEB 4KLBA 2E03A 4OELA 3MORA 1KHQA 4XR7A 4CDDB 3BC3A 3RVWA 3M99A 4N4ZA 6PADA 3K24A 3MHHA 4MZOA 4W5BA 3QSDA 3H7DA 2E01A 3F5VA 3OISA 1A6RA 2XU4A 1HUCB 4N79A 1MIRA 1ATKA 1ME3A 4XUIA 1YK8A 1MHWA 1EF7A 1POPA 4BPVA 1XKGA 3QJ3A 2DC6A 2DZZA 3PBHA 3OF9A 8PCHA 3N3GA 4AXMA 3BPFA 4YYRA 2DC7A 1CSBB 2GFOA 4YYQA 2AIMA 2O6XA 2DJFB 4CDFB 1NPZA 1BY8A 1PPNA 2IPPB 2R9CA 1GLOA 1KFUL 4CZWA 1DF0A 4DMYA 1NB5A 2BDLA 4PP1A 2P86A 2HD5A 4ZUXU 1NB3A 3H6SA 2YJ2A 1NQCA 3N3KA 2OP3A 2G8JA 1PPOA 3MHSA 2OZ2A 3U8EA 2FYEA 1DEUA 1AYVA 5EF4A 1U9XA 4W5CA 2JQGR 4X6JA 2GHUA 1X9YA 3IEJA 3BOWA 2DC9A 5CVOB 1U9QX 2FO5A 1CJLA 3DF0A 3H8CA 1AIMA 1F2AA 3KW9A 5CVMA 3S3RA 2AUZA 2R9MA 1PE6A 4P6EA 3B79A 1BP4A 3RVXA 1BGOA 2FRAA 3USVA 1CTEA 1ITOA 2PREA 3CBKA 3RVVA 1YVBA 2AVWA 7PCKA 4YYUA 2VHSA 1MS6A 3BPMA 1QMYA 1Y4HA 9PAPA 4YYVA 1SNKA 4MSXA 2R9OA 5EGWA 2NQAA 2Y5BA 1M6DA 2BDZA 4Q8GA 3H89A 3I06A 2P0RA 2ATOA 2ACTA 1MEGA 5J94A 3IOQA 5CHTA 1GECE 1U9VA 2IBIA 2DCBA 3P5VA 1KFXL 3KX1A 2FUDA 2NQGA 5FPWA 4HWYA 2NQIA 2DJGB 2PADA 3V6EA 4YYWA 1GCBA 4YYSA 1F29A 1VJVA 2R6NA 3ERVA 1PCIA 2G6DA 4QRXA 1O0EA 2YJCA 5A24A 3P5XA 4OEMA 1ICFA 4PP2E 3E1ZB 2PNSA 2AYOA 3O1GA 2HH5A 1CVZA 3CH3X 4WA6A 2CIOA 1FH0A 1PBHA 1KHPA 5F02A 5JH3A 1SP4B 1PIPA 1ZIVA 3K8UA 2DC8A 3KSEA 1ME4A 3PNRA 4X6IA 3OVXA 3IUTA 1EWOA 3CBJA 1CS8A 1GMYA 4QH6A 3P5WA 3H8BA 1U9WA 3ZUAA 2JQFR 1PXVA 3D6SA 1AYWA 3GCBA 3IMAA 3CH2X 1IWDA 2XU3A 4X6HA 1THEA 1CQDA 3N4CA 1KXRA 2PBHA 1AU0A 2F1GA 3PDFA 1MEMA 3KWZA 2DCAA 1AECA 4MZSA 2Y6EA 4BS6A 2CB5A 4YV8A 2AU1A 2DCCA 1NL6A 3I3TA 3HWNA 2FT2A 3MTNA 2G7YA 5K16A 4BS5A 4K7CA 2B1MA 1NLJA 2VHFA 3IV2A 1YALA 1AYUA 2P7UA 4Q8HA 1EWMA 3BWKA 3IHPA 4W4UA 1F2BA 2FRQA 4RY2A 5JA7A 1Y08A 2YJBA 3TNXA 2DCDA 4AXLA 3P5UA 1ZCMA 2YJ8A 3BCNA 5PADA 1PADA 2NQDB 2R9NA 1AU3A 3QT4A 2FQ9A 4I05A 4I04A 4G54A 1AU4A 1PPPA 1MDWA 3F75A 4YVAA 1YK7A 3HHIA 4BQVA 2B1NA 4P6GA 2H7JA 2AYNA 1BQIA 1TLOA 1STFE 3OF8A 3KKUA 4I07A 1PPDA 2R9FA 2HXZA 1CPJA 5CVNB 4FJCA 3HHAA 3WXEA 1VSNA 3K9MA 2C0YA 4CDCB 4QBBA 1TU6A 1CB5A 1EWLA 2WBFX 3HD3A 4FIPA 4QRGA 3O0UA 3V6CA 4BSQA 2G8EA 3C9EA 2AUXA 3LXSA 3WXGA 1QXPA 2XU5A 1YT7A 3WXFA 2FTDA 3KFQA 3LFYA 2HHNA 2OULA 5CHVA
chains in the Genus database with same CATH superfamily
2E00A 1QDQA 1TL9A 1AU2A 2JTCA 1QOLA 4QRVA 3PW3A 1U5IA 1F2CA 3OVZA 1UKFA 4FK5A 4PT5A 1K3BB 3AI8A 3NHEA 1CV8A 4PADA 1Q6KA 3S3QA 2XU1A 3KWBX 4DMXA 2E02A 1S4VA 2F7DA 4IP3A 2AS8A 4RF0A 2ARYA 1EWPA 1JQPA 4N8WA 4PI3A 2YJ9A 3MTVA 2DZYA 3OQCA 4CDEB 4KLBA 2E03A 4OELA 3MORA 1KHQA 4XR7A 4CDDB 5E6JA 4RF1A 3BC3A 4IUMA 3RVWA 3M99A 4N4ZA 6PADA 3K24A 3MHHA 4MZOA 4W5BA 3QSDA 3H7DA 2E01A 3PRPA 3F5VA 3OISA 1A6RA 2XU4A 1HUCB 2J7QA 1MIRA 4N79A 1ATKA 1ME3A 4OVZA 4XUIA 1YK8A 1MHWA 4P16A 1EF7A 1POPA 4BPVA 1XKGA 3QJ3A 2DC6A 3MJ5A 2DZZA 3PBHA 2BU3A 3OF9A 8PCHA 3N3GA 4AXMA 2AGAA 3BPFA 4YYRA 2DC7A 1CSBB 2GFOA 4YYQA 2AIMA 3C0RA 3TRKA 2O6XA 2DJFB 4CDFB 3BBAA 1NPZA 1BY8A 1PPNA 2IPPB 2J7QC 2UZJA 2R9CA 1GLOA 1KFUL 2JRIA 3PHUA 4CZWA 1DF0A 4DMYA 1NB5A 2BDLA 4HXDB 4PP1A 2P86A 2HD5A 4ZUXU 1NB3A 3H6SA 2YJ2A 4M0WA 1NQCA 3N3KA 2OP3A 2G8JA 1PPOA 3MHSA 2OZ2A 3U8EA 2FYEA 1DEUA 1AYVA 4WURA 5EF4A 1U9XA 4W5CA 2JQGR 4X6JA 2GHUA 1X9YA 5JZEA 3IEJA 3W30A 3BOWA 2DC9A 5CVOB 1U9QX 2FO5A 1CJLA 3DF0A 3H8CA 3W31A 1AIMA 1F2AA 3KW9A 5CVMA 5EZSA 3S3RA 2AUZA 2R9MA 1PE6A 4RNAA 4P6EA 3B79A 1BP4A 3RNVA 3RVXA 1BGOA 2FRAA 4OW0A 3USVA 1CTEA 1ITOA 2PREA 3CBKA 3RVVA 1YVBA 4RKXA 2AVWA 7PCKA 4YYUA 2FE8A 2VHSA 1MS6A 3BPMA 1QMYA 1Y4HA 9PAPA 4YYVA 3BB7A 1SNKA 4MSXA 2R9OA 5EGWA 2NQAA 2Y5BA 1M6DA 2BDZA 4Q8GA 3H89A 3I06A 2P0RA 2ATOA 2ACTA 4D8IA 1MEGA 5J94A 3IOQA 5CHTA 1GECE 1U9VA 2IBIA 3PT2A 2DCBA 3P5VA 1KFXL 3KX1A 2FUDA 2NQGA 5FPWA 4HWYA 2NQIA 2DJGB 2PADA 3V6EA 4YYWA 1GCBA 4YYSA 1F29A 1VJVA 2R6NA 3ERVA 1PCIA 2G6DA 4QRXA 1O0EA 2BTWB 2YJCA 5A24A 3P5XA 4OEMA 1ICFA 4PP2E 3E1ZB 2PNSA 2AYOA 3O1GA 2HH5A 1CVZA 3CH3X 4WA6A 2CIOA 1FH0A 1PBHA 1KHPA 5F02A 5JH3A 1SP4B 1PIPA 1ZIVA 3K8UA 2DC8A 3KSEA 3B21A 1ME4A 3PNRA 4X6IA 3OVXA 3IUTA 1EWOA 3CBJA 1CS8A 1GMYA 4QH6A 3P5WA 3H8BA 1U9WA 3ZUAA 2JQFR 1PXVA 2Z84A 4OVZB 4ZTBA 3D6SA 1AYWA 4XZXA 4A5UA 3GCBA 3IMAA 3CH2X 1IWDA 3PHXA 2XU3A 4X6HA 1THEA 1CQDA 3N4CA 1KXRA 2PBHA 1AU0A 2F1GA 3PDFA 1DKIA 1MEMA 4MM3B 5KO3A 3KWZA 2DCAA 1AECA 4MZSA 2Y6EA 4BS6A 2CB5A 4YV8A 2AU1A 2DCCA 1NL6A 4BOPA 3I3TA 2HWKA 3HWNA 4R3DA 2FT2A 3MTNA 2G7YA 5K16A 1YZBA 4BS5A 4K7CA 4MI7A 2B1MA 1NLJA 2VHFA 2DOSA 3IV2A 1YALA 1AYUA 2P7UA 4Q8HA 1EWMA 3BWKA 3IHPA 4W4UA 1F2BA 2FRQA 3TMPA 4RY2A 5JA7A 2BTWA 1Y08A 2YJBA 3TNXA 2DCDA 4AXLA 3P5UA 1ZCMA 2YJ8A 3BCNA 5PADA 1PADA 2NQDB 2R9NA 1AU3A 3QT4A 2FQ9A 1PVJA 3BY4A 4I05A 4I04A 4G54A 1AU4A 1PPPA 1MDWA 3F75A 4YVAA 1YK7A 3HHIA 4BQVA 2B1NA 4P6GA 2H7JA 2AYNA 1BQIA 1TLOA 1STFE 3OF8A 3KKUA 4I07A 1PPDA 3PRMA 2R9FA 2HXZA 4D8EA 1CPJA 3O65A 3MP2A 5CVNB 4FJCA 3IFUA 3ZNHA 4BOZA 4BOQA 3PHWA 3HHAA 3WXEA 1VSNA 3K9MA 2C0YA 4CDCB 4QBBA 1TU6A 1CB5A 1EWLA 2WBFX 3HD3A 4FIPA 4QRGA 3O0UA 4BOSA 3V6CA 4BSQA 2G8EA 4BOUA 3C9EA 2AUXA 3LXSA 3WXGA 1QXPA 5EZQA 4D8BA 2XU5A 3PSEA 1YT7A 3WXFA 4REZA 2FTDA 3KFQA 3LFYA 3E9SA 4GUAA 2HHNA 2OULA 5CHVA
chains in the Genus database with same CATH topology
2E00A 1QDQA 1TL9A 1AU2A 1QOLA 4QRVA 3PW3A 1U5IA 1F2CA 3OVZA 4FK5A 1K3BB 3AI8A 3NHEA 1CV8A 4PADA 1Q6KA 3S3QA 3LTWA 2XU1A 3KWBX 4DMXA 2E02A 1S4VA 2F7DA 2AS8A 2ARYA 1EWPA 1JQPA 4N8WA 4PI3A 2YJ9A 2DZYA 4CDEB 4KLBA 2E03A 4OELA 3MORA 2BSZA 1KHQA 4XR7A 4CDDB 3BC3A 3RVWA 3M99A 4N4ZA 1W6FA 6PADA 3K24A 3MHHA 4MZOA 4W5BA 3QSDA 3H7DA 2E01A 3F5VA 3OISA 1A6RA 2XU4A 1HUCB 4N79A 1MIRA 1ATKA 1ME3A 4XUIA 1YK8A 1MHWA 1EF7A 1POPA 4BPVA 1XKGA 3QJ3A 2DC6A 2DZZA 3PBHA 3OF9A 8PCHA 3N3GA 4AXMA 3BPFA 4YYRA 2DC7A 1CSBB 2GFOA 4YYQA 2AIMA 2O6XA 2DJFB 4CDFB 1NPZA 1BY8A 1PPNA 2IPPB 2R9CA 1GLOA 1KFUL 4CZWA 1DF0A 4DMYA 1NB5A 2BDLA 4PP1A 2P86A 2HD5A 4ZUXU 1NB3A 3H6SA 2YJ2A 1NQCA 3N3KA 2OP3A 2G8JA 1PPOA 3MHSA 2OZ2A 3U8EA 2FYEA 1DEUA 1AYVA 5EF4A 1U9XA 4W5CA 2JQGR 4X6JA 2GHUA 1X9YA 3IEJA 2VFCA 3BOWA 2VFBA 4GUZA 2DC9A 1W5RA 5CVOB 1U9QX 2FO5A 1CJLA 3DF0A 3H8CA 1AIMA 1F2AA 3KW9A 5CVMA 3S3RA 2AUZA 2R9MA 1PE6A 4P6EA 3B79A 1BP4A 3RVXA 1BGOA 2FRAA 3USVA 1CTEA 1ITOA 2PREA 3CBKA 3RVVA 1YVBA 2AVWA 7PCKA 4YYUA 2VHSA 1MS6A 3BPMA 1QMYA 1Y4HA 9PAPA 4YYVA 1GX3A 1SNKA 4MSXA 2R9OA 5EGWA 2NQAA 2Y5BA 1M6DA 2BDZA 4Q8GA 3H89A 3I06A 2P0RA 2ATOA 2ACTA 1MEGA 5J94A 3IOQA 5CHTA 1GECE 1U9VA 2IBIA 2DCBA 3P5VA 1KFXL 3KX1A 2FUDA 2NQGA 5FPWA 4HWYA 2NQIA 2DJGB 2PADA 3D9WA 3V6EA 4YYWA 1GCBA 4YYSA 1F29A 1VJVA 2R6NA 3ERVA 1PCIA 2G6DA 4QRXA 1O0EA 2YJCA 5A24A 3P5XA 4OEMA 1ICFA 4PP2E 3E1ZB 2PNSA 2AYOA 4C5PA 3O1GA 2HH5A 3CH3X 1CVZA 4WA6A 2CIOA 1FH0A 1PBHA 1KHPA 5F02A 5JH3A 1SP4B 1PIPA 1ZIVA 3K8UA 2DC8A 3KSEA 1ME4A 3PNRA 4X6IA 3OVXA 3IUTA 1EWOA 3CBJA 1CS8A 1GMYA 4QH6A 3P5WA 3H8BA 1U9WA 3ZUAA 2JQFR 1PXVA 3D6SA 1AYWA 3GCBA 3IMAA 3CH2X 1IWDA 2XU3A 4X6HA 1THEA 1CQDA 3N4CA 1KXRA 2PBHA 1AU0A 2F1GA 3PDFA 1MEMA 3KWZA 2DCAA 1AECA 1W4TA 4MZSA 2Y6EA 4BS6A 2CB5A 4YV8A 2AU1A 2DCCA 1NL6A 3I3TA 3HWNA 4B55A 2FT2A 3MTNA 2G7YA 5K16A 4BS5A 4K7CA 2B1MA 1NLJA 2VHFA 3IV2A 1YALA 1AYUA 1E2TA 2P7UA 4Q8HA 1EWMA 3BWKA 3IHPA 4W4UA 1F2BA 2FRQA 4RY2A 5JA7A 1Y08A 2YJBA 3TNXA 2DCDA 4AXLA 3P5UA 1ZCMA 2YJ8A 3BCNA 4NV7A 5PADA 1PADA 2NQDB 2R9NA 1AU3A 3QT4A 2FQ9A 4I05A 4I04A 4G54A 1AU4A 1PPPA 1MDWA 3F75A 4YVAA 1YK7A 3HHIA 4BQVA 2B1NA 4P6GA 2H7JA 2AYNA 1BQIA 1TLOA 1STFE 3OF8A 3KKUA 4I07A 1PPDA 2R9FA 2HXZA 1CPJA 5CVNB 4FJCA 3HHAA 4NV8A 3WXEA 1VSNA 3K9MA 2C0YA 4CDCB 4QBBA 1TU6A 1CB5A 1EWLA 2WBFX 3HD3A 4FIPA 4QRGA 3O0UA 3V6CA 4BSQA 2G8EA 3C9EA 2AUXA 3LXSA 3WXGA 1QXPA 2XU5A 1YT7A 3WXFA 2FTDA 3KFQA 3LFYA 4BGFA 2HHNA 2OULA 5CHVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2E00 A;  1QDQ A;  1TL9 A;  1AU2 A;  1QOL A;  4QRV A;  3PW3 A;  1U5I A;  1F2C A;  3OVZ A;  4FK5 A;  1K3B B;  3AI8 A;  3NHE A;  1CV8 A;  4PAD A;  1Q6K A;  3S3Q A;  2XU1 A;  3KWB X;  4DMX A;  2E02 A;  1S4V A;  2F7D A;  2AS8 A;  2ARY A;  1EWP A;  1JQP A;  4N8W A;  4PI3 A;  2YJ9 A;  2DZY A;  4CDE B;  4KLB A;  2E03 A;  4OEL A;  3MOR A;  1KHQ A;  4XR7 A;  4CDD B;  3BC3 A;  3RVW A;  3M99 A;  4N4Z A;  6PAD A;  3K24 A;  3MHH A;  4MZO A;  4W5B A;  3QSD A;  3H7D A;  2E01 A;  3F5V A;  3OIS A;  1A6R A;  2XU4 A;  1HUC B;  4N79 A;  1MIR A;  1ATK A;  1ME3 A;  4XUI A;  1YK8 A;  1MHW A;  1EF7 A;  1POP A;  4BPV A;  1XKG A;  3QJ3 A;  2DC6 A;  2DZZ A;  3PBH A;  3OF9 A;  8PCH A;  3N3G A;  4AXM A;  3BPF A;  4YYR A;  2DC7 A;  1CSB B;  2GFO A;  4YYQ A;  2AIM A;  2O6X A;  2DJF B;  4CDF B;  1NPZ A;  1BY8 A;  1PPN A;  2IPP B;  2R9C A;  1GLO A;  1KFU L;  4CZW A;  1DF0 A;  4DMY A;  1NB5 A;  2BDL A;  4PP1 A;  2P86 A;  2HD5 A;  4ZUX U;  1NB3 A;  3H6S A;  2YJ2 A;  1NQC A;  3N3K A;  2OP3 A;  2G8J A;  1PPO A;  3MHS A;  2OZ2 A;  3U8E A;  2FYE A;  1DEU A;  1AYV A;  5EF4 A;  1U9X A;  4W5C A;  2JQG R;  4X6J A;  2GHU A;  1X9Y A;  3IEJ A;  3BOW A;  2DC9 A;  5CVO B;  1U9Q X;  2FO5 A;  1CJL A;  3DF0 A;  3H8C A;  1AIM A;  1F2A A;  3KW9 A;  5CVM A;  3S3R A;  2AUZ A;  2R9M A;  1PE6 A;  4P6E A;  3B79 A;  1BP4 A;  3RVX A;  1BGO A;  2FRA A;  3USV A;  1CTE A;  1ITO A;  2PRE A;  3CBK A;  3RVV A;  1YVB A;  2AVW A;  7PCK A;  4YYU A;  2VHS A;  1MS6 A;  3BPM A;  1QMY A;  1Y4H A;  9PAP A;  4YYV A;  1SNK A;  4MSX A;  2R9O A;  5EGW A;  2NQA A;  2Y5B A;  1M6D A;  2BDZ A;  4Q8G A;  3H89 A;  3I06 A;  2P0R A;  2ATO A;  2ACT A;  1MEG A;  5J94 A;  3IOQ A;  5CHT A;  1GEC E;  1U9V A;  2IBI A;  2DCB A;  3P5V A;  1KFX L;  3KX1 A;  2FUD A;  2NQG A;  5FPW A;  4HWY A;  2NQI A;  2DJG B;  2PAD A;  3V6E A;  4YYW A;  1GCB A;  4YYS A;  1F29 A;  1VJV A;  2R6N A;  3ERV A;  1PCI A;  2G6D A;  4QRX A;  1O0E A;  2YJC A;  5A24 A;  3P5X A;  4OEM A;  1ICF A;  4PP2 E;  3E1Z B;  2PNS A;  2AYO A;  3O1G A;  2HH5 A;  1CVZ A;  3CH3 X;  4WA6 A;  2CIO A;  1FH0 A;  1PBH A;  1KHP A;  5F02 A;  5JH3 A;  1SP4 B;  1PIP A;  1ZIV A;  3K8U A;  2DC8 A;  3KSE A;  1ME4 A;  3PNR A;  4X6I A;  3OVX A;  3IUT A;  1EWO A;  3CBJ A;  1CS8 A;  1GMY A;  4QH6 A;  3P5W A;  3H8B A;  1U9W A;  3ZUA A;  2JQF R;  1PXV A;  3D6S A;  1AYW A;  3GCB A;  3IMA A;  3CH2 X;  1IWD A;  2XU3 A;  4X6H A;  1THE A;  1CQD A;  3N4C A;  1KXR A;  2PBH A;  1AU0 A;  2F1G A;  3PDF A;  1MEM A;  3KWZ A;  2DCA A;  1AEC A;  4MZS A;  2Y6E A;  4BS6 A;  2CB5 A;  4YV8 A;  2AU1 A;  2DCC A;  1NL6 A;  3I3T A;  3HWN A;  2FT2 A;  3MTN A;  2G7Y A;  5K16 A;  4BS5 A;  4K7C A;  2B1M A;  1NLJ A;  2VHF A;  3IV2 A;  1YAL A;  1AYU A;  2P7U A;  4Q8H A;  1EWM A;  3BWK A;  3IHP A;  4W4U A;  1F2B A;  2FRQ A;  4RY2 A;  5JA7 A;  1Y08 A;  2YJB A;  3TNX A;  2DCD A;  4AXL A;  3P5U A;  1ZCM A;  2YJ8 A;  3BCN A;  5PAD A;  1PAD A;  2NQD B;  2R9N A;  1AU3 A;  3QT4 A;  2FQ9 A;  4I05 A;  4I04 A;  4G54 A;  1AU4 A;  1PPP A;  1MDW A;  3F75 A;  4YVA A;  1YK7 A;  3HHI A;  4BQV A;  2B1N A;  4P6G A;  2H7J A;  2AYN A;  1BQI A;  1TLO A;  1STF E;  3OF8 A;  3KKU A;  4I07 A;  1PPD A;  2R9F A;  2HXZ A;  1CPJ A;  5CVN B;  4FJC A;  3HHA A;  3WXE A;  1VSN A;  3K9M A;  2C0Y A;  4CDC B;  4QBB A;  1TU6 A;  1CB5 A;  1EWL A;  2WBF X;  3HD3 A;  4FIP A;  4QRG A;  3O0U A;  3V6C A;  4BSQ A;  2G8E A;  3C9E A;  2AUX A;  3LXS A;  3WXG A;  1QXP A;  2XU5 A;  1YT7 A;  3WXF A;  2FTD A;  3KFQ A;  3LFY A;  2HHN A;  2OUL A;  5CHV A; 
#chains in the Genus database with same CATH topology
 2E00 A;  1QDQ A;  1TL9 A;  1AU2 A;  2JTC A;  1QOL A;  4QRV A;  3PW3 A;  1U5I A;  1F2C A;  3OVZ A;  1UKF A;  4FK5 A;  4PT5 A;  1K3B B;  3AI8 A;  3NHE A;  1CV8 A;  4PAD A;  1Q6K A;  3S3Q A;  2XU1 A;  3KWB X;  4DMX A;  2E02 A;  1S4V A;  2F7D A;  4IP3 A;  2AS8 A;  4RF0 A;  2ARY A;  1EWP A;  1JQP A;  4N8W A;  4PI3 A;  2YJ9 A;  3MTV A;  2DZY A;  3OQC A;  4CDE B;  4KLB A;  2E03 A;  4OEL A;  3MOR A;  1KHQ A;  4XR7 A;  4CDD B;  5E6J A;  4RF1 A;  3BC3 A;  4IUM A;  3RVW A;  3M99 A;  4N4Z A;  6PAD A;  3K24 A;  3MHH A;  4MZO A;  4W5B A;  3QSD A;  3H7D A;  2E01 A;  3PRP A;  3F5V A;  3OIS A;  1A6R A;  2XU4 A;  1HUC B;  2J7Q A;  1MIR A;  4N79 A;  1ATK A;  1ME3 A;  4OVZ A;  4XUI A;  1YK8 A;  1MHW A;  4P16 A;  1EF7 A;  1POP A;  4BPV A;  1XKG A;  3QJ3 A;  2DC6 A;  3MJ5 A;  2DZZ A;  3PBH A;  2BU3 A;  3OF9 A;  8PCH A;  3N3G A;  4AXM A;  2AGA A;  3BPF A;  4YYR A;  2DC7 A;  1CSB B;  2GFO A;  4YYQ A;  2AIM A;  3C0R A;  3TRK A;  2O6X A;  2DJF B;  4CDF B;  3BBA A;  1NPZ A;  1BY8 A;  1PPN A;  2IPP B;  2J7Q C;  2UZJ A;  2R9C A;  1GLO A;  1KFU L;  2JRI A;  3PHU A;  4CZW A;  1DF0 A;  4DMY A;  1NB5 A;  2BDL A;  4HXD B;  4PP1 A;  2P86 A;  2HD5 A;  4ZUX U;  1NB3 A;  3H6S A;  2YJ2 A;  4M0W A;  1NQC A;  3N3K A;  2OP3 A;  2G8J A;  1PPO A;  3MHS A;  2OZ2 A;  3U8E A;  2FYE A;  1DEU A;  1AYV A;  4WUR A;  5EF4 A;  1U9X A;  4W5C A;  2JQG R;  4X6J A;  2GHU A;  1X9Y A;  5JZE A;  3IEJ A;  3W30 A;  3BOW A;  2DC9 A;  5CVO B;  1U9Q X;  2FO5 A;  1CJL A;  3DF0 A;  3H8C A;  3W31 A;  1AIM A;  1F2A A;  3KW9 A;  5CVM A;  5EZS A;  3S3R A;  2AUZ A;  2R9M A;  1PE6 A;  4RNA A;  4P6E A;  3B79 A;  1BP4 A;  3RNV A;  3RVX A;  1BGO A;  2FRA A;  4OW0 A;  3USV A;  1CTE A;  1ITO A;  2PRE A;  3CBK A;  3RVV A;  1YVB A;  4RKX A;  2AVW A;  7PCK A;  4YYU A;  2FE8 A;  2VHS A;  1MS6 A;  3BPM A;  1QMY A;  1Y4H A;  9PAP A;  4YYV A;  3BB7 A;  1SNK A;  4MSX A;  2R9O A;  5EGW A;  2NQA A;  2Y5B A;  1M6D A;  2BDZ A;  4Q8G A;  3H89 A;  3I06 A;  2P0R A;  2ATO A;  2ACT A;  4D8I A;  1MEG A;  5J94 A;  3IOQ A;  5CHT A;  1GEC E;  1U9V A;  2IBI A;  3PT2 A;  2DCB A;  3P5V A;  1KFX L;  3KX1 A;  2FUD A;  2NQG A;  5FPW A;  4HWY A;  2NQI A;  2DJG B;  2PAD A;  3V6E A;  4YYW A;  1GCB A;  4YYS A;  1F29 A;  1VJV A;  2R6N A;  3ERV A;  1PCI A;  2G6D A;  4QRX A;  1O0E A;  2BTW B;  2YJC A;  5A24 A;  3P5X A;  4OEM A;  1ICF A;  4PP2 E;  3E1Z B;  2PNS A;  2AYO A;  3O1G A;  2HH5 A;  1CVZ A;  3CH3 X;  4WA6 A;  2CIO A;  1FH0 A;  1PBH A;  1KHP A;  5F02 A;  5JH3 A;  1SP4 B;  1PIP A;  1ZIV A;  3K8U A;  2DC8 A;  3KSE A;  3B21 A;  1ME4 A;  3PNR A;  4X6I A;  3OVX A;  3IUT A;  1EWO A;  3CBJ A;  1CS8 A;  1GMY A;  4QH6 A;  3P5W A;  3H8B A;  1U9W A;  3ZUA A;  2JQF R;  1PXV A;  2Z84 A;  4OVZ B;  4ZTB A;  3D6S A;  1AYW A;  4XZX A;  4A5U A;  3GCB A;  3IMA A;  3CH2 X;  1IWD A;  3PHX A;  2XU3 A;  4X6H A;  1THE A;  1CQD A;  3N4C A;  1KXR A;  2PBH A;  1AU0 A;  2F1G A;  3PDF A;  1DKI A;  1MEM A;  4MM3 B;  5KO3 A;  3KWZ A;  2DCA A;  1AEC A;  4MZS A;  2Y6E A;  4BS6 A;  2CB5 A;  4YV8 A;  2AU1 A;  2DCC A;  1NL6 A;  4BOP A;  3I3T A;  2HWK A;  3HWN A;  4R3D A;  2FT2 A;  3MTN A;  2G7Y A;  5K16 A;  1YZB A;  4BS5 A;  4K7C A;  4MI7 A;  2B1M A;  1NLJ A;  2VHF A;  2DOS A;  3IV2 A;  1YAL A;  1AYU A;  2P7U A;  4Q8H A;  1EWM A;  3BWK A;  3IHP A;  4W4U A;  1F2B A;  2FRQ A;  3TMP A;  4RY2 A;  5JA7 A;  2BTW A;  1Y08 A;  2YJB A;  3TNX A;  2DCD A;  4AXL A;  3P5U A;  1ZCM A;  2YJ8 A;  3BCN A;  5PAD A;  1PAD A;  2NQD B;  2R9N A;  1AU3 A;  3QT4 A;  2FQ9 A;  1PVJ A;  3BY4 A;  4I05 A;  4I04 A;  4G54 A;  1AU4 A;  1PPP A;  1MDW A;  3F75 A;  4YVA A;  1YK7 A;  3HHI A;  4BQV A;  2B1N A;  4P6G A;  2H7J A;  2AYN A;  1BQI A;  1TLO A;  1STF E;  3OF8 A;  3KKU A;  4I07 A;  1PPD A;  3PRM A;  2R9F A;  2HXZ A;  4D8E A;  1CPJ A;  3O65 A;  3MP2 A;  5CVN B;  4FJC A;  3IFU A;  3ZNH A;  4BOZ A;  4BOQ A;  3PHW A;  3HHA A;  3WXE A;  1VSN A;  3K9M A;  2C0Y A;  4CDC B;  4QBB A;  1TU6 A;  1CB5 A;  1EWL A;  2WBF X;  3HD3 A;  4FIP A;  4QRG A;  3O0U A;  4BOS A;  3V6C A;  4BSQ A;  2G8E A;  4BOU A;  3C9E A;  2AUX A;  3LXS A;  3WXG A;  1QXP A;  5EZQ A;  4D8B A;  2XU5 A;  3PSE A;  1YT7 A;  3WXF A;  4REZ A;  2FTD A;  3KFQ A;  3LFY A;  3E9S A;  4GUA A;  2HHN A;  2OUL A;  5CHV A; 
#chains in the Genus database with same CATH homology
 2E00 A;  1QDQ A;  1TL9 A;  1AU2 A;  1QOL A;  4QRV A;  3PW3 A;  1U5I A;  1F2C A;  3OVZ A;  4FK5 A;  1K3B B;  3AI8 A;  3NHE A;  1CV8 A;  4PAD A;  1Q6K A;  3S3Q A;  3LTW A;  2XU1 A;  3KWB X;  4DMX A;  2E02 A;  1S4V A;  2F7D A;  2AS8 A;  2ARY A;  1EWP A;  1JQP A;  4N8W A;  4PI3 A;  2YJ9 A;  2DZY A;  4CDE B;  4KLB A;  2E03 A;  4OEL A;  3MOR A;  2BSZ A;  1KHQ A;  4XR7 A;  4CDD B;  3BC3 A;  3RVW A;  3M99 A;  4N4Z A;  1W6F A;  6PAD A;  3K24 A;  3MHH A;  4MZO A;  4W5B A;  3QSD A;  3H7D A;  2E01 A;  3F5V A;  3OIS A;  1A6R A;  2XU4 A;  1HUC B;  4N79 A;  1MIR A;  1ATK A;  1ME3 A;  4XUI A;  1YK8 A;  1MHW A;  1EF7 A;  1POP A;  4BPV A;  1XKG A;  3QJ3 A;  2DC6 A;  2DZZ A;  3PBH A;  3OF9 A;  8PCH A;  3N3G A;  4AXM A;  3BPF A;  4YYR A;  2DC7 A;  1CSB B;  2GFO A;  4YYQ A;  2AIM A;  2O6X A;  2DJF B;  4CDF B;  1NPZ A;  1BY8 A;  1PPN A;  2IPP B;  2R9C A;  1GLO A;  1KFU L;  4CZW A;  1DF0 A;  4DMY A;  1NB5 A;  2BDL A;  4PP1 A;  2P86 A;  2HD5 A;  4ZUX U;  1NB3 A;  3H6S A;  2YJ2 A;  1NQC A;  3N3K A;  2OP3 A;  2G8J A;  1PPO A;  3MHS A;  2OZ2 A;  3U8E A;  2FYE A;  1DEU A;  1AYV A;  5EF4 A;  1U9X A;  4W5C A;  2JQG R;  4X6J A;  2GHU A;  1X9Y A;  3IEJ A;  2VFC A;  3BOW A;  2VFB A;  4GUZ A;  2DC9 A;  1W5R A;  5CVO B;  1U9Q X;  2FO5 A;  1CJL A;  3DF0 A;  3H8C A;  1AIM A;  1F2A A;  3KW9 A;  5CVM A;  3S3R A;  2AUZ A;  2R9M A;  1PE6 A;  4P6E A;  3B79 A;  1BP4 A;  3RVX A;  1BGO A;  2FRA A;  3USV A;  1CTE A;  1ITO A;  2PRE A;  3CBK A;  3RVV A;  1YVB A;  2AVW A;  7PCK A;  4YYU A;  2VHS A;  1MS6 A;  3BPM A;  1QMY A;  1Y4H A;  9PAP A;  4YYV A;  1GX3 A;  1SNK A;  4MSX A;  2R9O A;  5EGW A;  2NQA A;  2Y5B A;  1M6D A;  2BDZ A;  4Q8G A;  3H89 A;  3I06 A;  2P0R A;  2ATO A;  2ACT A;  1MEG A;  5J94 A;  3IOQ A;  5CHT A;  1GEC E;  1U9V A;  2IBI A;  2DCB A;  3P5V A;  1KFX L;  3KX1 A;  2FUD A;  2NQG A;  5FPW A;  4HWY A;  2NQI A;  2DJG B;  2PAD A;  3D9W A;  3V6E A;  4YYW A;  1GCB A;  4YYS A;  1F29 A;  1VJV A;  2R6N A;  3ERV A;  1PCI A;  2G6D A;  4QRX A;  1O0E A;  2YJC A;  5A24 A;  3P5X A;  4OEM A;  1ICF A;  4PP2 E;  3E1Z B;  2PNS A;  2AYO A;  4C5P A;  3O1G A;  2HH5 A;  3CH3 X;  1CVZ A;  4WA6 A;  2CIO A;  1FH0 A;  1PBH A;  1KHP A;  5F02 A;  5JH3 A;  1SP4 B;  1PIP A;  1ZIV A;  3K8U A;  2DC8 A;  3KSE A;  1ME4 A;  3PNR A;  4X6I A;  3OVX A;  3IUT A;  1EWO A;  3CBJ A;  1CS8 A;  1GMY A;  4QH6 A;  3P5W A;  3H8B A;  1U9W A;  3ZUA A;  2JQF R;  1PXV A;  3D6S A;  1AYW A;  3GCB A;  3IMA A;  3CH2 X;  1IWD A;  2XU3 A;  4X6H A;  1THE A;  1CQD A;  3N4C A;  1KXR A;  2PBH A;  1AU0 A;  2F1G A;  3PDF A;  1MEM A;  3KWZ A;  2DCA A;  1AEC A;  1W4T A;  4MZS A;  2Y6E A;  4BS6 A;  2CB5 A;  4YV8 A;  2AU1 A;  2DCC A;  1NL6 A;  3I3T A;  3HWN A;  4B55 A;  2FT2 A;  3MTN A;  2G7Y A;  5K16 A;  4BS5 A;  4K7C A;  2B1M A;  1NLJ A;  2VHF A;  3IV2 A;  1YAL A;  1AYU A;  1E2T A;  2P7U A;  4Q8H A;  1EWM A;  3BWK A;  3IHP A;  4W4U A;  1F2B A;  2FRQ A;  4RY2 A;  5JA7 A;  1Y08 A;  2YJB A;  3TNX A;  2DCD A;  4AXL A;  3P5U A;  1ZCM A;  2YJ8 A;  3BCN A;  4NV7 A;  5PAD A;  1PAD A;  2NQD B;  2R9N A;  1AU3 A;  3QT4 A;  2FQ9 A;  4I05 A;  4I04 A;  4G54 A;  1AU4 A;  1PPP A;  1MDW A;  3F75 A;  4YVA A;  1YK7 A;  3HHI A;  4BQV A;  2B1N A;  4P6G A;  2H7J A;  2AYN A;  1BQI A;  1TLO A;  1STF E;  3OF8 A;  3KKU A;  4I07 A;  1PPD A;  2R9F A;  2HXZ A;  1CPJ A;  5CVN B;  4FJC A;  3HHA A;  4NV8 A;  3WXE A;  1VSN A;  3K9M A;  2C0Y A;  4CDC B;  4QBB A;  1TU6 A;  1CB5 A;  1EWL A;  2WBF X;  3HD3 A;  4FIP A;  4QRG A;  3O0U A;  3V6C A;  4BSQ A;  2G8E A;  3C9E A;  2AUX A;  3LXS A;  3WXG A;  1QXP A;  2XU5 A;  1YT7 A;  3WXF A;  2FTD A;  3KFQ A;  3LFY A;  4BGF A;  2HHN A;  2OUL A;  5CHV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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