3PNRA

Structure of pbicp-c in complex with falcipain-2
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
240
structure length
240
Chain Sequence
MNYEEVIKKYRGEENFDHAAYDWRLHSGVTPVKDQKNCGSAWAFSSIGSVESQYAIRKNKLITLSEQELVDCSFKNYGCNGGLINNAFEDMIELGGICPDGDYPYVSDAPNLCNIDRCTEKYGIKNYLSVPDNKLKEALRFLGPISISVAVSDDFAFYKEGIFDGECGDQLNHAVMLVGFGMKEIVNPLTKKGEKHYYYIIKNSWGQQWGERGFINIETDESGLMRKCGLGTDAFIPLIE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for the regulation of cysteine-protease activity by a new class of protease inhibitors in Plasmodium.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Plasmodium falciparum
molecule keywords Falcipain 2
total genus 65
structure length 240
sequence length 240
ec nomenclature
pdb deposition date 2010-11-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 3pnrA00
2GFOA 1PPPA 2DZYA 1NPZA 1NB3A 1U9XA 3P5WA 3MHHA 2AUZA 2AUXA 3K24A 2FRQA 2G7YA 1BP4A 3KX1A 1QOLA 4Q8HA 2FO5A 2IPPB 4P6EA 1KXRA 3BC3A 3ERVA 5J94A 2HH5A 2PBHA 3QT4A 4FJCA 4AXLA 2CIOA 3BPMA 3O1GA 1KFXL 4I07A 1NLJA 3BCNA 5A24A 4I05A 3KWZA 5FPWA 1EF7A 2HHNA 3HWNA 1K3BB 5CHVA 4YYSA 2FQ9A 1O0EA 3BOWA 2AYNA 1CSBB 3PBHA 4N4ZA 2ATOA 2DZZA 3P5XA 5F02A 1U9VA 1YALA 1QMYA 2DCDA 2XU5A 2YJ8A 2E02A 2NQIA 2R9OA 3PNRA 1A6RA 2AYOA 1AYUA 1AYWA 1ME3A 2G8JA 2R6NA 1PPOA 3AI8A 1PPDA 1PCIA 2DC7A 1AU3A 3USVA 1PPNA 1MDWA 2B1MA 5CHTA 4P6GA 1CVZA 2P0RA 3H89A 2AS8A 4W4UA 1CS8A 2FRAA 3V6EA 1POPA 1NB5A 2PREA 3HHAA 3TNXA 2G8EA 3CH2X 1YK7A 1S4VA 3I3TA 1CJLA 3S3QA 3KW9A 2DCBA 2G6DA 8PCHA 4N8WA 2YJ9A 2DC6A 3V6CA 2HD5A 1GCBA 4OEMA 1MS6A 2DC8A 3WXGA 1ATKA 5JA7A 1F2AA 4YYVA 1MEMA 2E01A 2DCCA 6PADA 4X6JA 3NHEA 2AVWA 3C9EA 3HD3A 1TU6A 2P7UA 5JH3A 4QH6A 5CVMA 3BWKA 3MORA 2DCAA 4K7CA 4X6HA 3DF0A 1TL9A 2Y5BA 2ARYA 2YJ2A 4WA6A 4YYQA 4BSQA 3IEJA 1PADA 2E00A 4MZOA 3ZUAA 2HXZA 3OVZA 4QRGA 1ITOA 2XU4A 3OF8A 1KHPA 3IOQA 2DJGB 5EGWA 1VSNA 2BDLA 2FYEA 4QBBA 1QDQA 2F7DA 2CB5A 1QXPA 1DEUA 1AECA 3PW3A 3RVWA 2P86A 1SP4B 2NQDB 1VJVA 3M99A 4DMYA 3MHSA 3H7DA 1CPJA 2YJCA 3GCBA 4BS5A 2XU3A 1AU0A 3H6SA 4QRXA 3CBJA 5CVNB 1BQIA 1EWOA 5EF4A 1EWLA 4XUIA 2OULA 1BGOA 1XKGA 1MEGA 7PCKA 2IBIA 2FT2A 4QRVA 1STFE 3B79A 2R9NA 1KFUL 2AU1A 4BS6A 1HUCB 2OP3A 1KHQA 2JQFR 2DC9A 3OF9A 4PADA 1CV8A 2R9MA 1GMYA 3D6SA 3F5VA 2DJFB 1ICFA 4YYRA 1THEA 1GECE 1EWPA 2WBFX 3N4CA 1CQDA 1SNKA 1CB5A 1X9YA 5K16A 3IV2A 1PE6A 1TLOA 1GLOA 3P5VA 4G54A 3LFYA 1YK8A 1FH0A 1AU4A 4CZWA 3IUTA 3S3RA 2Y6EA 3K8UA 2R9FA 1ZIVA 4X6IA 2ACTA 2YJBA 4PI3A 3CBKA 9PAPA 3QJ3A 1U9QX 3IMAA 2FUDA 3BPFA 4OELA 3K9MA 4BQVA 3H8BA 4YYWA 3MTNA 3I06A 3KWBX 3OISA 2NQAA 3KKUA 1JQPA 3O0UA 4KLBA 1PBHA 1CTEA 1Y4HA 1AYVA 4CDFB 1MIRA 2C0YA 1Y08A 2E03A 3KSEA 4DMXA 1NQCA 1ZCMA 1MHWA 4ZUXU 1IWDA 3WXFA 3P5UA 4MSXA 1AU2A 3RVVA 1Q6KA 2AIMA 2BDZA 4YV8A 3OVXA 1BY8A 3F75A 5PADA 4W5BA 4W5CA 4CDDB 2NQGA 1U9WA 4CDCB 3E1ZB 1EWMA 4FK5A 1F2CA 2OZ2A 1M6DA 1F29A 1U5IA 3N3KA 2PNSA 4Q8GA 4RY2A 1PXVA 2O6XA 4PP1A 1DF0A 4XR7A 1YT7A 5CVOB 2GHUA 4MZSA 3KFQA 4PP2E 3RVXA 3WXEA 1PIPA 2PADA 3IHPA 3U8EA 2F1GA 2VHSA 3N3GA 2VHFA 2B1NA 4FIPA 1YVBA 1NL6A 4HWYA 2JQGR 4YYUA 1ME4A 4I04A 3HHIA 4AXMA 2FTDA 3PDFA 4BPVA 1F2BA 2XU1A 3LXSA 4YVAA 3QSDA 1AIMA 2H7JA 4CDEB 2R9CA 4N79A 3CH3X 3H8CA
chains in the Genus database with same CATH superfamily
2GFOA 4OW0A 1PPPA 2DZYA 1NPZA 1NB3A 3PT2A 1U9XA 3P5WA 2BU3A 3MHHA 2AUZA 2AUXA 3K24A 2FRQA 2G7YA 3BB7A 1BP4A 3KX1A 3IFUA 1QOLA 4Q8HA 2FO5A 2IPPB 4P6EA 1KXRA 3BC3A 3ERVA 5J94A 4R3DA 2HH5A 2PBHA 3QT4A 4D8IA 4FJCA 4AXLA 2CIOA 3BPMA 3O1GA 2FE8A 1KFXL 4I07A 1NLJA 3BCNA 5A24A 3OQCA 3RNVA 4I05A 3KWZA 5FPWA 1EF7A 2HHNA 3PRPA 3HWNA 1K3BB 5CHVA 4YYSA 4IUMA 2FQ9A 3ZNHA 1O0EA 3BOWA 2UZJA 2AYNA 1CSBB 3PBHA 4N4ZA 2ATOA 2DZZA 3P5XA 5F02A 1U9VA 1YALA 1QMYA 2DCDA 2XU5A 2YJ8A 2E02A 3MTVA 2NQIA 2R9OA 3PNRA 1A6RA 2AYOA 2BTWB 1AYUA 1AYWA 1ME3A 2G8JA 2R6NA 1PPOA 4MI7A 3AI8A 1PPDA 1PCIA 4OVZB 3W31A 4HXDB 2DC7A 1AU3A 3USVA 4BOZA 1PPNA 1MDWA 2B1MA 5CHTA 4P6GA 3PHUA 1CVZA 2P0RA 3H89A 2AS8A 4REZA 4W4UA 4BOSA 1CS8A 2FRAA 3W30A 3V6EA 3B21A 1POPA 1NB5A 2PREA 3HHAA 3TNXA 2G8EA 3CH2X 2DOSA 4BOPA 2J7QA 1YK7A 1S4VA 3I3TA 1CJLA 3S3QA 3KW9A 2DCBA 2G6DA 8PCHA 4N8WA 2YJ9A 2DC6A 3V6CA 2HD5A 1GCBA 4OEMA 1MS6A 2DC8A 4RF0A 3WXGA 1ATKA 5JA7A 1F2AA 4YYVA 1MEMA 2E01A 2J7QC 2DCCA 4P16A 6PADA 4X6JA 3NHEA 2AVWA 3C9EA 3HD3A 1TU6A 2P7UA 2JTCA 5JH3A 4QH6A 3TRKA 5CVMA 3BWKA 3MORA 2DCAA 4K7CA 4X6HA 3DF0A 1TL9A 2Y5BA 2ARYA 2YJ2A 4WURA 4WA6A 4YYQA 4BSQA 3IEJA 1PADA 2E00A 4MZOA 3ZUAA 2HXZA 3OVZA 4QRGA 1ITOA 2XU4A 3BBAA 3OF8A 1KHPA 3IOQA 2DJGB 5EGWA 1VSNA 2BDLA 2FYEA 4QBBA 1QDQA 2F7DA 2CB5A 1QXPA 1DEUA 1AECA 3PW3A 3RVWA 2P86A 1SP4B 2NQDB 1VJVA 3M99A 4DMYA 3MHSA 3H7DA 1CPJA 2YJCA 3GCBA 4XZXA 4BS5A 2Z84A 2XU3A 1AU0A 3H6SA 4QRXA 3CBJA 5CVNB 1BQIA 1EWOA 5EF4A 1EWLA 4D8EA 4XUIA 2OULA 1BGOA 4BOQA 1XKGA 1MEGA 7PCKA 2IBIA 2FT2A 4ZTBA 4QRVA 1STFE 3B79A 2R9NA 1KFUL 2AU1A 4BS6A 1HUCB 5EZSA 2OP3A 1KHQA 2JQFR 2DC9A 3OF9A 5E6JA 4PADA 4PT5A 1CV8A 2JRIA 2R9MA 4RNAA 4D8BA 1GMYA 3D6SA 3MP2A 3F5VA 2DJFB 1ICFA 4YYRA 1THEA 1GECE 1EWPA 2WBFX 3N4CA 1CQDA 1SNKA 1CB5A 1X9YA 5K16A 3IV2A 5JZEA 1PE6A 1TLOA 1GLOA 3P5VA 4G54A 3PHXA 3LFYA 1YK8A 1FH0A 1AU4A 4CZWA 3IUTA 3S3RA 3O65A 2Y6EA 3K8UA 2R9FA 1ZIVA 4GUAA 4X6IA 2ACTA 4RKXA 2YJBA 4PI3A 3CBKA 4RF1A 9PAPA 3QJ3A 3PRMA 1U9QX 3IMAA 3BY4A 4M0WA 2FUDA 3BPFA 4OELA 3K9MA 4BQVA 3H8BA 4YYWA 3MTNA 4BOUA 3I06A 3KWBX 1UKFA 3OISA 3MJ5A 2NQAA 3KKUA 1JQPA 3O0UA 4KLBA 1PBHA 3PSEA 3TMPA 1CTEA 1Y4HA 1AYVA 4CDFB 1MIRA 2C0YA 1Y08A 2E03A 3KSEA 4DMXA 1NQCA 1ZCMA 1MHWA 4ZUXU 1IWDA 5EZQA 3WXFA 3P5UA 4MSXA 1AU2A 3RVVA 1Q6KA 2AIMA 2BDZA 4YV8A 3OVXA 1BY8A 3F75A 5PADA 4W5BA 4W5CA 4CDDB 1YZBA 2NQGA 1U9WA 4CDCB 3E1ZB 1EWMA 2BTWA 4FK5A 1F2CA 2OZ2A 1M6DA 1F29A 1U5IA 4OVZA 3N3KA 2PNSA 4Q8GA 4A5UA 4RY2A 1PXVA 2O6XA 4PP1A 1DF0A 4XR7A 1YT7A 5CVOB 2GHUA 4MZSA 3KFQA 3E9SA 4PP2E 4IP3A 3RVXA 3WXEA 1PIPA 2PADA 3IHPA 3U8EA 2F1GA 2VHSA 3N3GA 3PHWA 3C0RA 2HWKA 2B1NA 2VHFA 4FIPA 1YVBA 1NL6A 4HWYA 2JQGR 4YYUA 4MM3B 1DKIA 1ME4A 4I04A 3HHIA 4AXMA 5KO3A 2FTDA 3PDFA 4BPVA 1F2BA 2XU1A 3LXSA 1PVJA 2AGAA 4YVAA 3QSDA 1AIMA 2H7JA 4CDEB 2R9CA 4N79A 3CH3X 3H8CA
chains in the Genus database with same CATH topology
2GFOA 1PPPA 2DZYA 1NPZA 1NB3A 1U9XA 3P5WA 3MHHA 2AUZA 2AUXA 3K24A 2FRQA 2G7YA 1BP4A 3KX1A 1QOLA 4Q8HA 2FO5A 2IPPB 4P6EA 1KXRA 3BC3A 3ERVA 5J94A 2HH5A 2PBHA 3QT4A 4FJCA 4AXLA 2CIOA 3BPMA 3O1GA 1KFXL 4I07A 1NLJA 3BCNA 5A24A 4I05A 3KWZA 5FPWA 1EF7A 2HHNA 3HWNA 1K3BB 5CHVA 4YYSA 2FQ9A 1O0EA 3BOWA 2AYNA 1CSBB 3PBHA 4N4ZA 1W5RA 2ATOA 2DZZA 3P5XA 5F02A 1U9VA 1YALA 1QMYA 2DCDA 2XU5A 2YJ8A 2E02A 2NQIA 2R9OA 3PNRA 1A6RA 2AYOA 1AYUA 1AYWA 1ME3A 2G8JA 2R6NA 1PPOA 3AI8A 4B55A 1PPDA 1PCIA 2DC7A 1AU3A 3USVA 1PPNA 1MDWA 2B1MA 5CHTA 4P6GA 1CVZA 2P0RA 3H89A 2AS8A 4W4UA 1CS8A 2FRAA 3V6EA 1POPA 1NB5A 4NV7A 2PREA 3HHAA 3TNXA 2G8EA 3CH2X 1W4TA 1YK7A 1S4VA 3I3TA 1CJLA 3S3QA 3KW9A 2DCBA 2G6DA 8PCHA 4N8WA 2YJ9A 2DC6A 3V6CA 2HD5A 1GCBA 4OEMA 1MS6A 2DC8A 3WXGA 1ATKA 5JA7A 1F2AA 4YYVA 1MEMA 2E01A 2DCCA 6PADA 4X6JA 3NHEA 2AVWA 3C9EA 3HD3A 1TU6A 2P7UA 5JH3A 4QH6A 5CVMA 3BWKA 3MORA 2DCAA 4K7CA 4X6HA 3DF0A 1TL9A 2Y5BA 2ARYA 2YJ2A 4WA6A 4YYQA 4BSQA 2VFCA 3IEJA 1PADA 2E00A 4MZOA 3ZUAA 2HXZA 3OVZA 4QRGA 1ITOA 2XU4A 2VFBA 3OF8A 1KHPA 3IOQA 1GX3A 2DJGB 5EGWA 1VSNA 2BDLA 2FYEA 4QBBA 1QDQA 2F7DA 2CB5A 1QXPA 1DEUA 1AECA 3PW3A 3RVWA 2P86A 1SP4B 2NQDB 1VJVA 3M99A 4DMYA 3MHSA 3H7DA 1CPJA 2YJCA 3GCBA 4BS5A 2XU3A 1AU0A 3H6SA 3D9WA 4QRXA 3CBJA 5CVNB 1BQIA 1EWOA 5EF4A 1EWLA 4XUIA 2OULA 1BGOA 1XKGA 1MEGA 7PCKA 2IBIA 2FT2A 4QRVA 1STFE 3B79A 2R9NA 1KFUL 2AU1A 4BS6A 1HUCB 2OP3A 1KHQA 2JQFR 2DC9A 3OF9A 4PADA 1CV8A 2R9MA 1GMYA 3D6SA 3F5VA 2DJFB 1ICFA 4YYRA 1THEA 1GECE 1EWPA 2WBFX 3N4CA 4NV8A 1CQDA 1SNKA 1CB5A 1X9YA 5K16A 3IV2A 1PE6A 1TLOA 1GLOA 3P5VA 4G54A 3LFYA 3LTWA 1YK8A 1FH0A 1AU4A 4CZWA 3IUTA 3S3RA 2Y6EA 3K8UA 2R9FA 1ZIVA 4X6IA 2ACTA 2YJBA 4PI3A 3CBKA 9PAPA 3QJ3A 1U9QX 3IMAA 2FUDA 3BPFA 4OELA 3K9MA 4BQVA 3H8BA 4YYWA 3MTNA 3I06A 3KWBX 3OISA 4BGFA 2NQAA 3KKUA 1JQPA 3O0UA 4KLBA 1PBHA 1CTEA 1Y4HA 1AYVA 4CDFB 1MIRA 2C0YA 1Y08A 2E03A 3KSEA 4DMXA 1NQCA 1ZCMA 1MHWA 4ZUXU 1IWDA 3WXFA 3P5UA 4MSXA 1AU2A 3RVVA 1Q6KA 2AIMA 2BDZA 4YV8A 3OVXA 1BY8A 3F75A 5PADA 4W5BA 4W5CA 4CDDB 2NQGA 1U9WA 4CDCB 3E1ZB 1EWMA 1E2TA 4FK5A 1W6FA 1F2CA 2OZ2A 1M6DA 1F29A 1U5IA 3N3KA 2PNSA 4Q8GA 4RY2A 1PXVA 2O6XA 4PP1A 1DF0A 4XR7A 1YT7A 5CVOB 2GHUA 4MZSA 3KFQA 4PP2E 4C5PA 2BSZA 3RVXA 3WXEA 1PIPA 2PADA 3IHPA 3U8EA 2F1GA 2VHSA 3N3GA 2VHFA 2B1NA 4FIPA 1YVBA 1NL6A 4HWYA 2JQGR 4YYUA 1ME4A 4I04A 3HHIA 4AXMA 2FTDA 3PDFA 4BPVA 1F2BA 2XU1A 3LXSA 4YVAA 3QSDA 1AIMA 4GUZA 2H7JA 4CDEB 2R9CA 4N79A 3CH3X 3H8CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GFO A;  1PPP A;  2DZY A;  1NPZ A;  1NB3 A;  1U9X A;  3P5W A;  3MHH A;  2AUZ A;  2AUX A;  3K24 A;  2FRQ A;  2G7Y A;  1BP4 A;  3KX1 A;  1QOL A;  4Q8H A;  2FO5 A;  2IPP B;  4P6E A;  1KXR A;  3BC3 A;  3ERV A;  5J94 A;  2HH5 A;  2PBH A;  3QT4 A;  4FJC A;  4AXL A;  2CIO A;  3BPM A;  3O1G A;  1KFX L;  4I07 A;  1NLJ A;  3BCN A;  5A24 A;  4I05 A;  3KWZ A;  5FPW A;  1EF7 A;  2HHN A;  3HWN A;  1K3B B;  5CHV A;  4YYS A;  2FQ9 A;  1O0E A;  3BOW A;  2AYN A;  1CSB B;  3PBH A;  4N4Z A;  2ATO A;  2DZZ A;  3P5X A;  5F02 A;  1U9V A;  1YAL A;  1QMY A;  2DCD A;  2XU5 A;  2YJ8 A;  2E02 A;  2NQI A;  2R9O A;  3PNR A;  1A6R A;  2AYO A;  1AYU A;  1AYW A;  1ME3 A;  2G8J A;  2R6N A;  1PPO A;  3AI8 A;  1PPD A;  1PCI A;  2DC7 A;  1AU3 A;  3USV A;  1PPN A;  1MDW A;  2B1M A;  5CHT A;  4P6G A;  1CVZ A;  2P0R A;  3H89 A;  2AS8 A;  4W4U A;  1CS8 A;  2FRA A;  3V6E A;  1POP A;  1NB5 A;  2PRE A;  3HHA A;  3TNX A;  2G8E A;  3CH2 X;  1YK7 A;  1S4V A;  3I3T A;  1CJL A;  3S3Q A;  3KW9 A;  2DCB A;  2G6D A;  8PCH A;  4N8W A;  2YJ9 A;  2DC6 A;  3V6C A;  2HD5 A;  1GCB A;  4OEM A;  1MS6 A;  2DC8 A;  3WXG A;  1ATK A;  5JA7 A;  1F2A A;  4YYV A;  1MEM A;  2E01 A;  2DCC A;  6PAD A;  4X6J A;  3NHE A;  2AVW A;  3C9E A;  3HD3 A;  1TU6 A;  2P7U A;  5JH3 A;  4QH6 A;  5CVM A;  3BWK A;  3MOR A;  2DCA A;  4K7C A;  4X6H A;  3DF0 A;  1TL9 A;  2Y5B A;  2ARY A;  2YJ2 A;  4WA6 A;  4YYQ A;  4BSQ A;  3IEJ A;  1PAD A;  2E00 A;  4MZO A;  3ZUA A;  2HXZ A;  3OVZ A;  4QRG A;  1ITO A;  2XU4 A;  3OF8 A;  1KHP A;  3IOQ A;  2DJG B;  5EGW A;  1VSN A;  2BDL A;  2FYE A;  4QBB A;  1QDQ A;  2F7D A;  2CB5 A;  1QXP A;  1DEU A;  1AEC A;  3PW3 A;  3RVW A;  2P86 A;  1SP4 B;  2NQD B;  1VJV A;  3M99 A;  4DMY A;  3MHS A;  3H7D A;  1CPJ A;  2YJC A;  3GCB A;  4BS5 A;  2XU3 A;  1AU0 A;  3H6S A;  4QRX A;  3CBJ A;  5CVN B;  1BQI A;  1EWO A;  5EF4 A;  1EWL A;  4XUI A;  2OUL A;  1BGO A;  1XKG A;  1MEG A;  7PCK A;  2IBI A;  2FT2 A;  4QRV A;  1STF E;  3B79 A;  2R9N A;  1KFU L;  2AU1 A;  4BS6 A;  1HUC B;  2OP3 A;  1KHQ A;  2JQF R;  2DC9 A;  3OF9 A;  4PAD A;  1CV8 A;  2R9M A;  1GMY A;  3D6S A;  3F5V A;  2DJF B;  1ICF A;  4YYR A;  1THE A;  1GEC E;  1EWP A;  2WBF X;  3N4C A;  1CQD A;  1SNK A;  1CB5 A;  1X9Y A;  5K16 A;  3IV2 A;  1PE6 A;  1TLO A;  1GLO A;  3P5V A;  4G54 A;  3LFY A;  1YK8 A;  1FH0 A;  1AU4 A;  4CZW A;  3IUT A;  3S3R A;  2Y6E A;  3K8U A;  2R9F A;  1ZIV A;  4X6I A;  2ACT A;  2YJB A;  4PI3 A;  3CBK A;  9PAP A;  3QJ3 A;  1U9Q X;  3IMA A;  2FUD A;  3BPF A;  4OEL A;  3K9M A;  4BQV A;  3H8B A;  4YYW A;  3MTN A;  3I06 A;  3KWB X;  3OIS A;  2NQA A;  3KKU A;  1JQP A;  3O0U A;  4KLB A;  1PBH A;  1CTE A;  1Y4H A;  1AYV A;  4CDF B;  1MIR A;  2C0Y A;  1Y08 A;  2E03 A;  3KSE A;  4DMX A;  1NQC A;  1ZCM A;  1MHW A;  4ZUX U;  1IWD A;  3WXF A;  3P5U A;  4MSX A;  1AU2 A;  3RVV A;  1Q6K A;  2AIM A;  2BDZ A;  4YV8 A;  3OVX A;  1BY8 A;  3F75 A;  5PAD A;  4W5B A;  4W5C A;  4CDD B;  2NQG A;  1U9W A;  4CDC B;  3E1Z B;  1EWM A;  4FK5 A;  1F2C A;  2OZ2 A;  1M6D A;  1F29 A;  1U5I A;  3N3K A;  2PNS A;  4Q8G A;  4RY2 A;  1PXV A;  2O6X A;  4PP1 A;  1DF0 A;  4XR7 A;  1YT7 A;  5CVO B;  2GHU A;  4MZS A;  3KFQ A;  4PP2 E;  3RVX A;  3WXE A;  1PIP A;  2PAD A;  3IHP A;  3U8E A;  2F1G A;  2VHS A;  3N3G A;  2VHF A;  2B1N A;  4FIP A;  1YVB A;  1NL6 A;  4HWY A;  2JQG R;  4YYU A;  1ME4 A;  4I04 A;  3HHI A;  4AXM A;  2FTD A;  3PDF A;  4BPV A;  1F2B A;  2XU1 A;  3LXS A;  4YVA A;  3QSD A;  1AIM A;  2H7J A;  4CDE B;  2R9C A;  4N79 A;  3CH3 X;  3H8C A; 
#chains in the Genus database with same CATH topology
 2GFO A;  4OW0 A;  1PPP A;  2DZY A;  1NPZ A;  1NB3 A;  3PT2 A;  1U9X A;  3P5W A;  2BU3 A;  3MHH A;  2AUZ A;  2AUX A;  3K24 A;  2FRQ A;  2G7Y A;  3BB7 A;  1BP4 A;  3KX1 A;  3IFU A;  1QOL A;  4Q8H A;  2FO5 A;  2IPP B;  4P6E A;  1KXR A;  3BC3 A;  3ERV A;  5J94 A;  4R3D A;  2HH5 A;  2PBH A;  3QT4 A;  4D8I A;  4FJC A;  4AXL A;  2CIO A;  3BPM A;  3O1G A;  2FE8 A;  1KFX L;  4I07 A;  1NLJ A;  3BCN A;  5A24 A;  3OQC A;  3RNV A;  4I05 A;  3KWZ A;  5FPW A;  1EF7 A;  2HHN A;  3PRP A;  3HWN A;  1K3B B;  5CHV A;  4YYS A;  4IUM A;  2FQ9 A;  3ZNH A;  1O0E A;  3BOW A;  2UZJ A;  2AYN A;  1CSB B;  3PBH A;  4N4Z A;  2ATO A;  2DZZ A;  3P5X A;  5F02 A;  1U9V A;  1YAL A;  1QMY A;  2DCD A;  2XU5 A;  2YJ8 A;  2E02 A;  3MTV A;  2NQI A;  2R9O A;  3PNR A;  1A6R A;  2AYO A;  2BTW B;  1AYU A;  1AYW A;  1ME3 A;  2G8J A;  2R6N A;  1PPO A;  4MI7 A;  3AI8 A;  1PPD A;  1PCI A;  4OVZ B;  3W31 A;  4HXD B;  2DC7 A;  1AU3 A;  3USV A;  4BOZ A;  1PPN A;  1MDW A;  2B1M A;  5CHT A;  4P6G A;  3PHU A;  1CVZ A;  2P0R A;  3H89 A;  2AS8 A;  4REZ A;  4W4U A;  4BOS A;  1CS8 A;  2FRA A;  3W30 A;  3V6E A;  3B21 A;  1POP A;  1NB5 A;  2PRE A;  3HHA A;  3TNX A;  2G8E A;  3CH2 X;  2DOS A;  4BOP A;  2J7Q A;  1YK7 A;  1S4V A;  3I3T A;  1CJL A;  3S3Q A;  3KW9 A;  2DCB A;  2G6D A;  8PCH A;  4N8W A;  2YJ9 A;  2DC6 A;  3V6C A;  2HD5 A;  1GCB A;  4OEM A;  1MS6 A;  2DC8 A;  4RF0 A;  3WXG A;  1ATK A;  5JA7 A;  1F2A A;  4YYV A;  1MEM A;  2E01 A;  2J7Q C;  2DCC A;  4P16 A;  6PAD A;  4X6J A;  3NHE A;  2AVW A;  3C9E A;  3HD3 A;  1TU6 A;  2P7U A;  2JTC A;  5JH3 A;  4QH6 A;  3TRK A;  5CVM A;  3BWK A;  3MOR A;  2DCA A;  4K7C A;  4X6H A;  3DF0 A;  1TL9 A;  2Y5B A;  2ARY A;  2YJ2 A;  4WUR A;  4WA6 A;  4YYQ A;  4BSQ A;  3IEJ A;  1PAD A;  2E00 A;  4MZO A;  3ZUA A;  2HXZ A;  3OVZ A;  4QRG A;  1ITO A;  2XU4 A;  3BBA A;  3OF8 A;  1KHP A;  3IOQ A;  2DJG B;  5EGW A;  1VSN A;  2BDL A;  2FYE A;  4QBB A;  1QDQ A;  2F7D A;  2CB5 A;  1QXP A;  1DEU A;  1AEC A;  3PW3 A;  3RVW A;  2P86 A;  1SP4 B;  2NQD B;  1VJV A;  3M99 A;  4DMY A;  3MHS A;  3H7D A;  1CPJ A;  2YJC A;  3GCB A;  4XZX A;  4BS5 A;  2Z84 A;  2XU3 A;  1AU0 A;  3H6S A;  4QRX A;  3CBJ A;  5CVN B;  1BQI A;  1EWO A;  5EF4 A;  1EWL A;  4D8E A;  4XUI A;  2OUL A;  1BGO A;  4BOQ A;  1XKG A;  1MEG A;  7PCK A;  2IBI A;  2FT2 A;  4ZTB A;  4QRV A;  1STF E;  3B79 A;  2R9N A;  1KFU L;  2AU1 A;  4BS6 A;  1HUC B;  5EZS A;  2OP3 A;  1KHQ A;  2JQF R;  2DC9 A;  3OF9 A;  5E6J A;  4PAD A;  4PT5 A;  1CV8 A;  2JRI A;  2R9M A;  4RNA A;  4D8B A;  1GMY A;  3D6S A;  3MP2 A;  3F5V A;  2DJF B;  1ICF A;  4YYR A;  1THE A;  1GEC E;  1EWP A;  2WBF X;  3N4C A;  1CQD A;  1SNK A;  1CB5 A;  1X9Y A;  5K16 A;  3IV2 A;  5JZE A;  1PE6 A;  1TLO A;  1GLO A;  3P5V A;  4G54 A;  3PHX A;  3LFY A;  1YK8 A;  1FH0 A;  1AU4 A;  4CZW A;  3IUT A;  3S3R A;  3O65 A;  2Y6E A;  3K8U A;  2R9F A;  1ZIV A;  4GUA A;  4X6I A;  2ACT A;  4RKX A;  2YJB A;  4PI3 A;  3CBK A;  4RF1 A;  9PAP A;  3QJ3 A;  3PRM A;  1U9Q X;  3IMA A;  3BY4 A;  4M0W A;  2FUD A;  3BPF A;  4OEL A;  3K9M A;  4BQV A;  3H8B A;  4YYW A;  3MTN A;  4BOU A;  3I06 A;  3KWB X;  1UKF A;  3OIS A;  3MJ5 A;  2NQA A;  3KKU A;  1JQP A;  3O0U A;  4KLB A;  1PBH A;  3PSE A;  3TMP A;  1CTE A;  1Y4H A;  1AYV A;  4CDF B;  1MIR A;  2C0Y A;  1Y08 A;  2E03 A;  3KSE A;  4DMX A;  1NQC A;  1ZCM A;  1MHW A;  4ZUX U;  1IWD A;  5EZQ A;  3WXF A;  3P5U A;  4MSX A;  1AU2 A;  3RVV A;  1Q6K A;  2AIM A;  2BDZ A;  4YV8 A;  3OVX A;  1BY8 A;  3F75 A;  5PAD A;  4W5B A;  4W5C A;  4CDD B;  1YZB A;  2NQG A;  1U9W A;  4CDC B;  3E1Z B;  1EWM A;  2BTW A;  4FK5 A;  1F2C A;  2OZ2 A;  1M6D A;  1F29 A;  1U5I A;  4OVZ A;  3N3K A;  2PNS A;  4Q8G A;  4A5U A;  4RY2 A;  1PXV A;  2O6X A;  4PP1 A;  1DF0 A;  4XR7 A;  1YT7 A;  5CVO B;  2GHU A;  4MZS A;  3KFQ A;  3E9S A;  4PP2 E;  4IP3 A;  3RVX A;  3WXE A;  1PIP A;  2PAD A;  3IHP A;  3U8E A;  2F1G A;  2VHS A;  3N3G A;  3PHW A;  3C0R A;  2HWK A;  2B1N A;  2VHF A;  4FIP A;  1YVB A;  1NL6 A;  4HWY A;  2JQG R;  4YYU A;  4MM3 B;  1DKI A;  1ME4 A;  4I04 A;  3HHI A;  4AXM A;  5KO3 A;  2FTD A;  3PDF A;  4BPV A;  1F2B A;  2XU1 A;  3LXS A;  1PVJ A;  2AGA A;  4YVA A;  3QSD A;  1AIM A;  2H7J A;  4CDE B;  2R9C A;  4N79 A;  3CH3 X;  3H8C A; 
#chains in the Genus database with same CATH homology
 2GFO A;  1PPP A;  2DZY A;  1NPZ A;  1NB3 A;  1U9X A;  3P5W A;  3MHH A;  2AUZ A;  2AUX A;  3K24 A;  2FRQ A;  2G7Y A;  1BP4 A;  3KX1 A;  1QOL A;  4Q8H A;  2FO5 A;  2IPP B;  4P6E A;  1KXR A;  3BC3 A;  3ERV A;  5J94 A;  2HH5 A;  2PBH A;  3QT4 A;  4FJC A;  4AXL A;  2CIO A;  3BPM A;  3O1G A;  1KFX L;  4I07 A;  1NLJ A;  3BCN A;  5A24 A;  4I05 A;  3KWZ A;  5FPW A;  1EF7 A;  2HHN A;  3HWN A;  1K3B B;  5CHV A;  4YYS A;  2FQ9 A;  1O0E A;  3BOW A;  2AYN A;  1CSB B;  3PBH A;  4N4Z A;  1W5R A;  2ATO A;  2DZZ A;  3P5X A;  5F02 A;  1U9V A;  1YAL A;  1QMY A;  2DCD A;  2XU5 A;  2YJ8 A;  2E02 A;  2NQI A;  2R9O A;  3PNR A;  1A6R A;  2AYO A;  1AYU A;  1AYW A;  1ME3 A;  2G8J A;  2R6N A;  1PPO A;  3AI8 A;  4B55 A;  1PPD A;  1PCI A;  2DC7 A;  1AU3 A;  3USV A;  1PPN A;  1MDW A;  2B1M A;  5CHT A;  4P6G A;  1CVZ A;  2P0R A;  3H89 A;  2AS8 A;  4W4U A;  1CS8 A;  2FRA A;  3V6E A;  1POP A;  1NB5 A;  4NV7 A;  2PRE A;  3HHA A;  3TNX A;  2G8E A;  3CH2 X;  1W4T A;  1YK7 A;  1S4V A;  3I3T A;  1CJL A;  3S3Q A;  3KW9 A;  2DCB A;  2G6D A;  8PCH A;  4N8W A;  2YJ9 A;  2DC6 A;  3V6C A;  2HD5 A;  1GCB A;  4OEM A;  1MS6 A;  2DC8 A;  3WXG A;  1ATK A;  5JA7 A;  1F2A A;  4YYV A;  1MEM A;  2E01 A;  2DCC A;  6PAD A;  4X6J A;  3NHE A;  2AVW A;  3C9E A;  3HD3 A;  1TU6 A;  2P7U A;  5JH3 A;  4QH6 A;  5CVM A;  3BWK A;  3MOR A;  2DCA A;  4K7C A;  4X6H A;  3DF0 A;  1TL9 A;  2Y5B A;  2ARY A;  2YJ2 A;  4WA6 A;  4YYQ A;  4BSQ A;  2VFC A;  3IEJ A;  1PAD A;  2E00 A;  4MZO A;  3ZUA A;  2HXZ A;  3OVZ A;  4QRG A;  1ITO A;  2XU4 A;  2VFB A;  3OF8 A;  1KHP A;  3IOQ A;  1GX3 A;  2DJG B;  5EGW A;  1VSN A;  2BDL A;  2FYE A;  4QBB A;  1QDQ A;  2F7D A;  2CB5 A;  1QXP A;  1DEU A;  1AEC A;  3PW3 A;  3RVW A;  2P86 A;  1SP4 B;  2NQD B;  1VJV A;  3M99 A;  4DMY A;  3MHS A;  3H7D A;  1CPJ A;  2YJC A;  3GCB A;  4BS5 A;  2XU3 A;  1AU0 A;  3H6S A;  3D9W A;  4QRX A;  3CBJ A;  5CVN B;  1BQI A;  1EWO A;  5EF4 A;  1EWL A;  4XUI A;  2OUL A;  1BGO A;  1XKG A;  1MEG A;  7PCK A;  2IBI A;  2FT2 A;  4QRV A;  1STF E;  3B79 A;  2R9N A;  1KFU L;  2AU1 A;  4BS6 A;  1HUC B;  2OP3 A;  1KHQ A;  2JQF R;  2DC9 A;  3OF9 A;  4PAD A;  1CV8 A;  2R9M A;  1GMY A;  3D6S A;  3F5V A;  2DJF B;  1ICF A;  4YYR A;  1THE A;  1GEC E;  1EWP A;  2WBF X;  3N4C A;  4NV8 A;  1CQD A;  1SNK A;  1CB5 A;  1X9Y A;  5K16 A;  3IV2 A;  1PE6 A;  1TLO A;  1GLO A;  3P5V A;  4G54 A;  3LFY A;  3LTW A;  1YK8 A;  1FH0 A;  1AU4 A;  4CZW A;  3IUT A;  3S3R A;  2Y6E A;  3K8U A;  2R9F A;  1ZIV A;  4X6I A;  2ACT A;  2YJB A;  4PI3 A;  3CBK A;  9PAP A;  3QJ3 A;  1U9Q X;  3IMA A;  2FUD A;  3BPF A;  4OEL A;  3K9M A;  4BQV A;  3H8B A;  4YYW A;  3MTN A;  3I06 A;  3KWB X;  3OIS A;  4BGF A;  2NQA A;  3KKU A;  1JQP A;  3O0U A;  4KLB A;  1PBH A;  1CTE A;  1Y4H A;  1AYV A;  4CDF B;  1MIR A;  2C0Y A;  1Y08 A;  2E03 A;  3KSE A;  4DMX A;  1NQC A;  1ZCM A;  1MHW A;  4ZUX U;  1IWD A;  3WXF A;  3P5U A;  4MSX A;  1AU2 A;  3RVV A;  1Q6K A;  2AIM A;  2BDZ A;  4YV8 A;  3OVX A;  1BY8 A;  3F75 A;  5PAD A;  4W5B A;  4W5C A;  4CDD B;  2NQG A;  1U9W A;  4CDC B;  3E1Z B;  1EWM A;  1E2T A;  4FK5 A;  1W6F A;  1F2C A;  2OZ2 A;  1M6D A;  1F29 A;  1U5I A;  3N3K A;  2PNS A;  4Q8G A;  4RY2 A;  1PXV A;  2O6X A;  4PP1 A;  1DF0 A;  4XR7 A;  1YT7 A;  5CVO B;  2GHU A;  4MZS A;  3KFQ A;  4PP2 E;  4C5P A;  2BSZ A;  3RVX A;  3WXE A;  1PIP A;  2PAD A;  3IHP A;  3U8E A;  2F1G A;  2VHS A;  3N3G A;  2VHF A;  2B1N A;  4FIP A;  1YVB A;  1NL6 A;  4HWY A;  2JQG R;  4YYU A;  1ME4 A;  4I04 A;  3HHI A;  4AXM A;  2FTD A;  3PDF A;  4BPV A;  1F2B A;  2XU1 A;  3LXS A;  4YVA A;  3QSD A;  1AIM A;  4GUZ A;  2H7J A;  4CDE B;  2R9C A;  4N79 A;  3CH3 X;  3H8C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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