2ARYA

Catalytic domain of human calpain-1
Total Genus 89
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
322
structure length
322
Chain Sequence
NAIKYLGQDYEQLRVRCLQSGTLFRDEAFPPVPQSLGYKDLGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNDTLLHRVVPHGQSFQNGYAGIFHFQLWQFGEWVDVVVDDLLPIKDGKLVFVHSAEGNEFWSALLEKAYAKVNGSYEALSGGSTSEGFEDFTGGVTEWYELRKAPSDLYQIILKALERGSLLGCSIDISSVLDMEAITFKKLVKGHAYSVTGAKQVNYRGQVVSLIRMRNPWGEVEWTGAWSDSSSEWNNVDPYERDQLRVKMEDGEFWMSFRDFMREFTRLEICNLT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Crystal Structures of Human Calpains 1 and 9 Imply Diverse Mechanisms of Action and Auto-inhibition
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Calpain-1 catalytic subunit
total genus 89
structure length 322
sequence length 322
chains with identical sequence B
ec nomenclature ec 3.4.22.52: Calpain-1.
pdb deposition date 2005-08-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00648 Peptidase_C2 Calpain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2aryA02
2ARYA 2Y6EA 4PP2E 2HXZA 1X9YA 3RVWA 1KXRA 1AU4A 3CH2X 1GECE 3S3RA 3BPFA 3P5XA 3WXEA 2DC7A 3IMAA 2YJ9A 3KW9A 2FTDA 5CVMA 4YYQA 2FRQA 2DZYA 2DCCA 1HUCB 1YALA 2AYNA 1FH0A 4X6HA 3USVA 5CVOB 4W4UA 1EWPA 2IPPB 3P5VA 4K7CA 2P7UA 1AIMA 1S4VA 4HWYA 1SP4B 5PADA 1EWOA 2OULA 1BQIA 1IWDA 2FYEA 1DEUA 2DC6A 1TU6A 3H8BA 3WXGA 1CV8A 2NQGA 2PNSA 1A6RA 1PE6A 3GCBA 4MSXA 1NPZA 1PBHA 2P86A 2FT2A 1GLOA 2AVWA 2G8JA 3IEJA 3QSDA 1MEMA 1JQPA 3KFQA 1ZCMA 3RVVA 4CDDB 3PNRA 2HH5A 3QJ3A 4YYVA 4YYRA 1QMYA 2FRAA 1NLJA 1F29A 2O6XA 1F2AA 2DCAA 1NB3A 4YVAA 5EF4A 2AUXA 4X6IA 1KHQA 3MHSA 2G7YA 3BCNA 4WA6A 1ICFA 2PADA 4BQVA 3HD3A 8PCHA 3K24A 2R9FA 3H8CA 5JH3A 3CBKA 2E01A 3QT4A 5J94A 2R9NA 1NQCA 2H7JA 1BGOA 1MIRA 3N3GA 3MTNA 4PP1A 4CZWA 1NB5A 4QH6A 1U9XA 3MHHA 3E1ZB 2FQ9A 1ATKA 1PCIA 4G54A 4QRVA 3P5UA 5JA7A 1PIPA 3BPMA 5A24A 3DF0A 2PBHA 4CDFB 6PADA 2B1NA 3B79A 1CPJA 1M6DA 2E02A 2ACTA 4CDEB 2XU3A 3O0UA 1K3BB 2R6NA 5CVNB 5F02A 2XU5A 3N4CA 1AYUA 4FJCA 1AU3A 1THEA 4RY2A 5K16A 1ZIVA 1U9QX 3OVXA 3K9MA 1PPNA 2VHFA 1Y4HA 3PW3A 3IUTA 4N79A 4DMXA 1Q6KA 1MS6A 3F75A 4I05A 2DJGB 2IBIA 2AIMA 3KWBX 2AS8A 1Y08A 2F1GA 1POPA 1EWMA 3IHPA 3V6EA 1F2CA 3LXSA 4CDCB 2AYOA 3TNXA 1QDQA 2HHNA 3CBJA 1GMYA 3ZUAA 1PXVA 3OISA 3C9EA 1TL9A 5CHTA 3S3QA 3BWKA 1ME3A 1CJLA 1ME4A 2XU4A 2DZZA 3HHAA 5FPWA 1PPOA 1GCBA 3F5VA 1QOLA 4Q8HA 1U9WA 2PREA 1KFUL 1U9VA 3RVXA 1XKGA 1YT7A 2AU1A 3H6SA 4QRGA 3CH3X 2G6DA 1CB5A 1PPPA 2OP3A 2FUDA 1SNKA 2NQDB 3OVZA 5EGWA 2P0RA 3I3TA 3OF9A 3D6SA 3IV2A 4YYUA 2GHUA 4I04A 1PADA 4XUIA 4QRXA 3PDFA 4P6EA 1YK7A 1YK8A 2AUZA 1F2BA 2NQIA 4FIPA 1CS8A 4ZUXU 2YJ8A 1VSNA 2BDLA 3N3KA 1NL6A 3H7DA 2CB5A 4I07A 1MHWA 2XU1A 2B1MA 3HWNA 2C0YA 2R9OA 3V6CA 3WXFA 2YJ2A 1AU0A 4BSQA 3BC3A 2CIOA 1O0EA 4AXMA 1CQDA 7PCKA 2FO5A 4FK5A 1BY8A 3IOQA 2VHSA 3M99A 4N8WA 3NHEA 4OELA 4W5CA 1STFE 2DCDA 4PI3A 4YYWA 1MDWA 2Y5BA 2NQAA 1MEGA 1AYVA 2E00A 9PAPA 5CHVA 1QXPA 4OEMA 2JQGR 1CSBB 4YV8A 2DJFB 3KX1A 1EWLA 4KLBA 3I06A 4MZSA 2DC9A 4AXLA 3ERVA 2BDZA 2GFOA 3KSEA 4Q8GA 3PBHA 2R9MA 3P5WA 2YJCA 2E03A 2WBFX 4BPVA 3BOWA 2ATOA 4P6GA 1KHPA 1ITOA 1U5IA 1EF7A 4BS6A 3OF8A 4N4ZA 4W5BA 3HHIA 1CVZA 4XR7A 2DCBA 1YVBA 2JQFR 4BS5A 2OZ2A 3U8EA 1TLOA 3LFYA 2YJBA 4PADA 3K8UA 1AYWA 4DMYA 1KFXL 1VJVA 1CTEA 2HD5A 4MZOA 4X6JA 3AI8A 3H89A 3O1GA 3KWZA 2R9CA 1PPDA 2F7DA 1DF0A 2DC8A 3MORA 3KKUA 1AU2A 1AECA 2G8EA 4QBBA 1BP4A 4YYSA
chains in the Genus database with same CATH superfamily
2ARYA 2Y6EA 4PP2E 5E6JA 2HXZA 1X9YA 3RVWA 1KXRA 1AU4A 3CH2X 2J7QC 1GECE 3S3RA 3BPFA 3P5XA 3WXEA 2DC7A 3IMAA 2YJ9A 3KW9A 2FTDA 5CVMA 4YYQA 2FRQA 2DZYA 2JTCA 4D8IA 2DCCA 1HUCB 1YALA 2AYNA 3PT2A 1FH0A 3MJ5A 4X6HA 4IUMA 3USVA 4OVZA 5JZEA 5CVOB 4W4UA 1EWPA 2IPPB 3P5VA 4K7CA 2P7UA 1AIMA 4BOUA 1S4VA 4HWYA 1SP4B 5PADA 1EWOA 2OULA 1BQIA 1IWDA 2FYEA 4P16A 1DEUA 4BOSA 2DC6A 1TU6A 3H8BA 3WXGA 1CV8A 2NQGA 3OQCA 2PNSA 1A6RA 1PE6A 3GCBA 4MSXA 1NPZA 1PBHA 2UZJA 2P86A 2FT2A 1GLOA 2AVWA 2G8JA 3IEJA 3QSDA 1MEMA 1JQPA 3KFQA 4RKXA 1ZCMA 3RVVA 4CDDB 3PNRA 2HH5A 3QJ3A 4YYVA 4YYRA 1QMYA 2FRAA 1NLJA 1F29A 2O6XA 1F2AA 2DCAA 1NB3A 4YVAA 5EF4A 2AUXA 4X6IA 1KHQA 1YZBA 2BU3A 4BOZA 3MHSA 2G7YA 2BTWB 3BCNA 4WA6A 1ICFA 2PADA 4BQVA 3HD3A 3O65A 8PCHA 3K24A 2R9FA 3IFUA 3H8CA 5JH3A 2FE8A 3CBKA 2E01A 3QT4A 2JRIA 5J94A 2R9NA 1NQCA 2H7JA 1BGOA 1MIRA 3N3GA 3MTNA 2HWKA 4PP1A 4CZWA 1NB5A 4QH6A 1U9XA 3MHHA 3E1ZB 2FQ9A 1ATKA 1PCIA 4G54A 4QRVA 3P5UA 5JA7A 1PIPA 4RF0A 3BPMA 4RF1A 5A24A 3ZNHA 2Z84A 3DF0A 2PBHA 4CDFB 6PADA 2B1NA 3B79A 1CPJA 1M6DA 2E02A 3PHXA 2ACTA 4CDEB 2XU3A 3O0UA 1K3BB 2R6NA 5CVNB 5F02A 2XU5A 3N4CA 1AYUA 4FJCA 1AU3A 1THEA 4RY2A 5K16A 1ZIVA 1U9QX 3OVXA 3K9MA 1PPNA 2VHFA 1Y4HA 3PW3A 3IUTA 4N79A 4DMXA 1Q6KA 1MS6A 3F75A 3MP2A 4HXDB 4I05A 2DJGB 2IBIA 2AIMA 3KWBX 2AS8A 3TRKA 1Y08A 2F1GA 1POPA 1EWMA 3IHPA 3V6EA 1F2CA 3LXSA 4CDCB 2AYOA 3TNXA 1PVJA 1QDQA 2HHNA 3B21A 3CBJA 1GMYA 3ZUAA 1PXVA 3TMPA 3PHUA 3BY4A 3OISA 3C9EA 4GUAA 1TL9A 5CHTA 3S3QA 3BWKA 1ME3A 1CJLA 1ME4A 2XU4A 4IP3A 2DZZA 3HHAA 5FPWA 1PPOA 1GCBA 3F5VA 4A5UA 1QOLA 4Q8HA 2J7QA 1U9WA 2PREA 1KFUL 1U9VA 3RVXA 1XKGA 1YT7A 2AU1A 3H6SA 4QRGA 3CH3X 2G6DA 1CB5A 1PPPA 4RNAA 2OP3A 2FUDA 1SNKA 3W31A 2NQDB 3OVZA 5EGWA 2P0RA 3I3TA 3OF9A 3D6SA 3IV2A 1UKFA 2GHUA 4YYUA 4I04A 3BBAA 1PADA 4XUIA 4QRXA 3PDFA 4P6EA 1YK7A 1YK8A 2AUZA 4XZXA 1F2BA 2NQIA 4FIPA 3BB7A 1CS8A 4ZUXU 2YJ8A 4OW0A 1VSNA 3C0RA 2BDLA 4PT5A 3N3KA 1NL6A 3H7DA 2CB5A 4I07A 1MHWA 2XU1A 2B1MA 3HWNA 4MM3B 2C0YA 2R9OA 3V6CA 3WXFA 2YJ2A 1AU0A 4BSQA 2DOSA 3E9SA 3BC3A 2CIOA 1O0EA 4WURA 4MI7A 4AXMA 2BTWA 1CQDA 4R3DA 7PCKA 2FO5A 4FK5A 4BOQA 4D8EA 1BY8A 3IOQA 2VHSA 3M99A 4N8WA 1DKIA 4D8BA 3NHEA 4OELA 4W5CA 1STFE 2DCDA 4PI3A 3PSEA 5EZSA 4YYWA 3PRMA 1MDWA 2Y5BA 4ZTBA 2NQAA 1MEGA 2AGAA 5KO3A 1AYVA 4REZA 2E00A 9PAPA 5CHVA 1QXPA 4OEMA 2JQGR 1CSBB 4YV8A 4BOPA 2DJFB 3KX1A 1EWLA 4KLBA 3I06A 4MZSA 2DC9A 4AXLA 3ERVA 2BDZA 2GFOA 3KSEA 4Q8GA 3PBHA 2R9MA 3P5WA 2YJCA 2E03A 2WBFX 4BPVA 3BOWA 2ATOA 4M0WA 4P6GA 5EZQA 1KHPA 1ITOA 1U5IA 4OVZB 1EF7A 4BS6A 3OF8A 3PHWA 4N4ZA 4W5BA 3HHIA 1CVZA 4XR7A 2DCBA 1YVBA 2JQFR 3RNVA 4BS5A 2OZ2A 3U8EA 1TLOA 3LFYA 3W30A 2YJBA 4PADA 3K8UA 1AYWA 4DMYA 1KFXL 1VJVA 1CTEA 3PRPA 2HD5A 4MZOA 4X6JA 3O1GA 3AI8A 3MTVA 3H89A 3KWZA 2R9CA 1PPDA 2F7DA 1DF0A 2DC8A 3MORA 3KKUA 1AU2A 1AECA 2G8EA 4QBBA 1BP4A 4YYSA
chains in the Genus database with same CATH topology
2ARYA 2Y6EA 4PP2E 2HXZA 1X9YA 3RVWA 1KXRA 1AU4A 3CH2X 1GECE 3S3RA 3BPFA 3P5XA 3WXEA 2DC7A 3IMAA 2YJ9A 3KW9A 2FTDA 5CVMA 4YYQA 2FRQA 2DZYA 3D9WA 2DCCA 1HUCB 1YALA 2AYNA 1FH0A 4X6HA 4GUZA 3USVA 5CVOB 4W4UA 1EWPA 2IPPB 3P5VA 4K7CA 2P7UA 1AIMA 1S4VA 4HWYA 1SP4B 5PADA 1EWOA 2OULA 1BQIA 1IWDA 2FYEA 1DEUA 2DC6A 1TU6A 3H8BA 3WXGA 1CV8A 2NQGA 2PNSA 1A6RA 4MSXA 1PE6A 3GCBA 1NPZA 1PBHA 2P86A 2FT2A 1GLOA 2AVWA 2G8JA 2VFBA 3IEJA 3QSDA 1MEMA 1JQPA 3KFQA 1ZCMA 1W6FA 3RVVA 4CDDB 3PNRA 2HH5A 3QJ3A 4YYVA 4NV7A 4YYRA 1QMYA 2FRAA 1NLJA 1F29A 2O6XA 1F2AA 2DCAA 1NB3A 4YVAA 5EF4A 2AUXA 4X6IA 1KHQA 3MHSA 2G7YA 3BCNA 4WA6A 1ICFA 2PADA 4BQVA 3HD3A 8PCHA 3K24A 2R9FA 3H8CA 5JH3A 3CBKA 2E01A 3QT4A 5J94A 2R9NA 1NQCA 2H7JA 4NV8A 1BGOA 1MIRA 3N3GA 4C5PA 3MTNA 4PP1A 4CZWA 1NB5A 4QH6A 1U9XA 3MHHA 3E1ZB 2FQ9A 1ATKA 1PCIA 4G54A 4QRVA 3P5UA 5JA7A 1PIPA 3BPMA 5A24A 3DF0A 2PBHA 4CDFB 6PADA 2B1NA 3B79A 1CPJA 1M6DA 2E02A 2ACTA 4CDEB 2XU3A 3O0UA 1K3BB 2R6NA 5CVNB 5F02A 2XU5A 3N4CA 1AYUA 4FJCA 1AU3A 1E2TA 1THEA 1GX3A 4RY2A 5K16A 1ZIVA 1U9QX 3OVXA 3K9MA 1PPNA 2VHFA 1Y4HA 3PW3A 3IUTA 4N79A 4DMXA 1Q6KA 1MS6A 3F75A 4I05A 2DJGB 2IBIA 2AIMA 3KWBX 2AS8A 1Y08A 2F1GA 4BGFA 1POPA 1EWMA 3IHPA 3V6EA 1F2CA 1W5RA 3LXSA 4CDCB 2AYOA 3TNXA 1QDQA 2HHNA 3CBJA 1GMYA 3ZUAA 1PXVA 3OISA 3C9EA 1TL9A 5CHTA 3S3QA 3BWKA 1ME3A 1CJLA 1ME4A 2XU4A 2DZZA 3HHAA 5FPWA 1PPOA 1GCBA 3F5VA 1QOLA 4Q8HA 1U9WA 2PREA 1KFUL 1U9VA 3RVXA 1XKGA 1YT7A 2AU1A 3H6SA 4QRGA 3CH3X 2G6DA 1CB5A 1PPPA 2OP3A 2FUDA 1SNKA 2NQDB 3OVZA 5EGWA 2P0RA 3I3TA 3OF9A 3D6SA 3IV2A 4YYUA 2GHUA 4I04A 1PADA 4XUIA 4QRXA 3PDFA 4P6EA 1YK7A 1YK8A 2AUZA 1F2BA 2NQIA 4FIPA 1CS8A 4ZUXU 2YJ8A 1VSNA 2BDLA 3N3KA 1NL6A 3H7DA 2CB5A 4I07A 1MHWA 2XU1A 2B1MA 3HWNA 2C0YA 2R9OA 3V6CA 3WXFA 2YJ2A 1AU0A 4BSQA 3BC3A 2CIOA 1O0EA 4AXMA 1CQDA 7PCKA 2FO5A 4FK5A 2VFCA 1BY8A 3IOQA 4B55A 2VHSA 3M99A 2BSZA 4N8WA 3NHEA 4OELA 4W5CA 1STFE 2DCDA 4PI3A 4YYWA 1MDWA 3LTWA 2Y5BA 2NQAA 1MEGA 1AYVA 2E00A 9PAPA 5CHVA 1QXPA 4OEMA 2JQGR 1CSBB 4YV8A 2DJFB 3KX1A 1EWLA 4KLBA 3I06A 4MZSA 2DC9A 4AXLA 3ERVA 2BDZA 2GFOA 3KSEA 4Q8GA 3PBHA 2R9MA 3P5WA 2YJCA 2E03A 2WBFX 4BPVA 3BOWA 2ATOA 4P6GA 1KHPA 1ITOA 1U5IA 1EF7A 4BS6A 3OF8A 4N4ZA 4W5BA 3HHIA 1CVZA 4XR7A 2DCBA 1YVBA 2JQFR 4BS5A 2OZ2A 3U8EA 1TLOA 3LFYA 2YJBA 4PADA 3K8UA 1AYWA 4DMYA 1KFXL 1VJVA 1CTEA 2HD5A 4MZOA 4X6JA 3O1GA 3AI8A 3H89A 1W4TA 3KWZA 2R9CA 1PPDA 2F7DA 1DF0A 2DC8A 3MORA 3KKUA 1AU2A 1AECA 2G8EA 4QBBA 1BP4A 4YYSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ARY A;  2Y6E A;  4PP2 E;  2HXZ A;  1X9Y A;  3RVW A;  1KXR A;  1AU4 A;  3CH2 X;  1GEC E;  3S3R A;  3BPF A;  3P5X A;  3WXE A;  2DC7 A;  3IMA A;  2YJ9 A;  3KW9 A;  2FTD A;  5CVM A;  4YYQ A;  2FRQ A;  2DZY A;  2DCC A;  1HUC B;  1YAL A;  2AYN A;  1FH0 A;  4X6H A;  3USV A;  5CVO B;  4W4U A;  1EWP A;  2IPP B;  3P5V A;  4K7C A;  2P7U A;  1AIM A;  1S4V A;  4HWY A;  1SP4 B;  5PAD A;  1EWO A;  2OUL A;  1BQI A;  1IWD A;  2FYE A;  1DEU A;  2DC6 A;  1TU6 A;  3H8B A;  3WXG A;  1CV8 A;  2NQG A;  2PNS A;  1A6R A;  1PE6 A;  3GCB A;  4MSX A;  1NPZ A;  1PBH A;  2P86 A;  2FT2 A;  1GLO A;  2AVW A;  2G8J A;  3IEJ A;  3QSD A;  1MEM A;  1JQP A;  3KFQ A;  1ZCM A;  3RVV A;  4CDD B;  3PNR A;  2HH5 A;  3QJ3 A;  4YYV A;  4YYR A;  1QMY A;  2FRA A;  1NLJ A;  1F29 A;  2O6X A;  1F2A A;  2DCA A;  1NB3 A;  4YVA A;  5EF4 A;  2AUX A;  4X6I A;  1KHQ A;  3MHS A;  2G7Y A;  3BCN A;  4WA6 A;  1ICF A;  2PAD A;  4BQV A;  3HD3 A;  8PCH A;  3K24 A;  2R9F A;  3H8C A;  5JH3 A;  3CBK A;  2E01 A;  3QT4 A;  5J94 A;  2R9N A;  1NQC A;  2H7J A;  1BGO A;  1MIR A;  3N3G A;  3MTN A;  4PP1 A;  4CZW A;  1NB5 A;  4QH6 A;  1U9X A;  3MHH A;  3E1Z B;  2FQ9 A;  1ATK A;  1PCI A;  4G54 A;  4QRV A;  3P5U A;  5JA7 A;  1PIP A;  3BPM A;  5A24 A;  3DF0 A;  2PBH A;  4CDF B;  6PAD A;  2B1N A;  3B79 A;  1CPJ A;  1M6D A;  2E02 A;  2ACT A;  4CDE B;  2XU3 A;  3O0U A;  1K3B B;  2R6N A;  5CVN B;  5F02 A;  2XU5 A;  3N4C A;  1AYU A;  4FJC A;  1AU3 A;  1THE A;  4RY2 A;  5K16 A;  1ZIV A;  1U9Q X;  3OVX A;  3K9M A;  1PPN A;  2VHF A;  1Y4H A;  3PW3 A;  3IUT A;  4N79 A;  4DMX A;  1Q6K A;  1MS6 A;  3F75 A;  4I05 A;  2DJG B;  2IBI A;  2AIM A;  3KWB X;  2AS8 A;  1Y08 A;  2F1G A;  1POP A;  1EWM A;  3IHP A;  3V6E A;  1F2C A;  3LXS A;  4CDC B;  2AYO A;  3TNX A;  1QDQ A;  2HHN A;  3CBJ A;  1GMY A;  3ZUA A;  1PXV A;  3OIS A;  3C9E A;  1TL9 A;  5CHT A;  3S3Q A;  3BWK A;  1ME3 A;  1CJL A;  1ME4 A;  2XU4 A;  2DZZ A;  3HHA A;  5FPW A;  1PPO A;  1GCB A;  3F5V A;  1QOL A;  4Q8H A;  1U9W A;  2PRE A;  1KFU L;  1U9V A;  3RVX A;  1XKG A;  1YT7 A;  2AU1 A;  3H6S A;  4QRG A;  3CH3 X;  2G6D A;  1CB5 A;  1PPP A;  2OP3 A;  2FUD A;  1SNK A;  2NQD B;  3OVZ A;  5EGW A;  2P0R A;  3I3T A;  3OF9 A;  3D6S A;  3IV2 A;  4YYU A;  2GHU A;  4I04 A;  1PAD A;  4XUI A;  4QRX A;  3PDF A;  4P6E A;  1YK7 A;  1YK8 A;  2AUZ A;  1F2B A;  2NQI A;  4FIP A;  1CS8 A;  4ZUX U;  2YJ8 A;  1VSN A;  2BDL A;  3N3K A;  1NL6 A;  3H7D A;  2CB5 A;  4I07 A;  1MHW A;  2XU1 A;  2B1M A;  3HWN A;  2C0Y A;  2R9O A;  3V6C A;  3WXF A;  2YJ2 A;  1AU0 A;  4BSQ A;  3BC3 A;  2CIO A;  1O0E A;  4AXM A;  1CQD A;  7PCK A;  2FO5 A;  4FK5 A;  1BY8 A;  3IOQ A;  2VHS A;  3M99 A;  4N8W A;  3NHE A;  4OEL A;  4W5C A;  1STF E;  2DCD A;  4PI3 A;  4YYW A;  1MDW A;  2Y5B A;  2NQA A;  1MEG A;  1AYV A;  2E00 A;  9PAP A;  5CHV A;  1QXP A;  4OEM A;  2JQG R;  1CSB B;  4YV8 A;  2DJF B;  3KX1 A;  1EWL A;  4KLB A;  3I06 A;  4MZS A;  2DC9 A;  4AXL A;  3ERV A;  2BDZ A;  2GFO A;  3KSE A;  4Q8G A;  3PBH A;  2R9M A;  3P5W A;  2YJC A;  2E03 A;  2WBF X;  4BPV A;  3BOW A;  2ATO A;  4P6G A;  1KHP A;  1ITO A;  1U5I A;  1EF7 A;  4BS6 A;  3OF8 A;  4N4Z A;  4W5B A;  3HHI A;  1CVZ A;  4XR7 A;  2DCB A;  1YVB A;  2JQF R;  4BS5 A;  2OZ2 A;  3U8E A;  1TLO A;  3LFY A;  2YJB A;  4PAD A;  3K8U A;  1AYW A;  4DMY A;  1KFX L;  1VJV A;  1CTE A;  2HD5 A;  4MZO A;  4X6J A;  3AI8 A;  3H89 A;  3O1G A;  3KWZ A;  2R9C A;  1PPD A;  2F7D A;  1DF0 A;  2DC8 A;  3MOR A;  3KKU A;  1AU2 A;  1AEC A;  2G8E A;  4QBB A;  1BP4 A;  4YYS A; 
#chains in the Genus database with same CATH topology
 2ARY A;  2Y6E A;  4PP2 E;  5E6J A;  2HXZ A;  1X9Y A;  3RVW A;  1KXR A;  1AU4 A;  3CH2 X;  2J7Q C;  1GEC E;  3S3R A;  3BPF A;  3P5X A;  3WXE A;  2DC7 A;  3IMA A;  2YJ9 A;  3KW9 A;  2FTD A;  5CVM A;  4YYQ A;  2FRQ A;  2DZY A;  2JTC A;  4D8I A;  2DCC A;  1HUC B;  1YAL A;  2AYN A;  3PT2 A;  1FH0 A;  3MJ5 A;  4X6H A;  4IUM A;  3USV A;  4OVZ A;  5JZE A;  5CVO B;  4W4U A;  1EWP A;  2IPP B;  3P5V A;  4K7C A;  2P7U A;  1AIM A;  4BOU A;  1S4V A;  4HWY A;  1SP4 B;  5PAD A;  1EWO A;  2OUL A;  1BQI A;  1IWD A;  2FYE A;  4P16 A;  1DEU A;  4BOS A;  2DC6 A;  1TU6 A;  3H8B A;  3WXG A;  1CV8 A;  2NQG A;  3OQC A;  2PNS A;  1A6R A;  1PE6 A;  3GCB A;  4MSX A;  1NPZ A;  1PBH A;  2UZJ A;  2P86 A;  2FT2 A;  1GLO A;  2AVW A;  2G8J A;  3IEJ A;  3QSD A;  1MEM A;  1JQP A;  3KFQ A;  4RKX A;  1ZCM A;  3RVV A;  4CDD B;  3PNR A;  2HH5 A;  3QJ3 A;  4YYV A;  4YYR A;  1QMY A;  2FRA A;  1NLJ A;  1F29 A;  2O6X A;  1F2A A;  2DCA A;  1NB3 A;  4YVA A;  5EF4 A;  2AUX A;  4X6I A;  1KHQ A;  1YZB A;  2BU3 A;  4BOZ A;  3MHS A;  2G7Y A;  2BTW B;  3BCN A;  4WA6 A;  1ICF A;  2PAD A;  4BQV A;  3HD3 A;  3O65 A;  8PCH A;  3K24 A;  2R9F A;  3IFU A;  3H8C A;  5JH3 A;  2FE8 A;  3CBK A;  2E01 A;  3QT4 A;  2JRI A;  5J94 A;  2R9N A;  1NQC A;  2H7J A;  1BGO A;  1MIR A;  3N3G A;  3MTN A;  2HWK A;  4PP1 A;  4CZW A;  1NB5 A;  4QH6 A;  1U9X A;  3MHH A;  3E1Z B;  2FQ9 A;  1ATK A;  1PCI A;  4G54 A;  4QRV A;  3P5U A;  5JA7 A;  1PIP A;  4RF0 A;  3BPM A;  4RF1 A;  5A24 A;  3ZNH A;  2Z84 A;  3DF0 A;  2PBH A;  4CDF B;  6PAD A;  2B1N A;  3B79 A;  1CPJ A;  1M6D A;  2E02 A;  3PHX A;  2ACT A;  4CDE B;  2XU3 A;  3O0U A;  1K3B B;  2R6N A;  5CVN B;  5F02 A;  2XU5 A;  3N4C A;  1AYU A;  4FJC A;  1AU3 A;  1THE A;  4RY2 A;  5K16 A;  1ZIV A;  1U9Q X;  3OVX A;  3K9M A;  1PPN A;  2VHF A;  1Y4H A;  3PW3 A;  3IUT A;  4N79 A;  4DMX A;  1Q6K A;  1MS6 A;  3F75 A;  3MP2 A;  4HXD B;  4I05 A;  2DJG B;  2IBI A;  2AIM A;  3KWB X;  2AS8 A;  3TRK A;  1Y08 A;  2F1G A;  1POP A;  1EWM A;  3IHP A;  3V6E A;  1F2C A;  3LXS A;  4CDC B;  2AYO A;  3TNX A;  1PVJ A;  1QDQ A;  2HHN A;  3B21 A;  3CBJ A;  1GMY A;  3ZUA A;  1PXV A;  3TMP A;  3PHU A;  3BY4 A;  3OIS A;  3C9E A;  4GUA A;  1TL9 A;  5CHT A;  3S3Q A;  3BWK A;  1ME3 A;  1CJL A;  1ME4 A;  2XU4 A;  4IP3 A;  2DZZ A;  3HHA A;  5FPW A;  1PPO A;  1GCB A;  3F5V A;  4A5U A;  1QOL A;  4Q8H A;  2J7Q A;  1U9W A;  2PRE A;  1KFU L;  1U9V A;  3RVX A;  1XKG A;  1YT7 A;  2AU1 A;  3H6S A;  4QRG A;  3CH3 X;  2G6D A;  1CB5 A;  1PPP A;  4RNA A;  2OP3 A;  2FUD A;  1SNK A;  3W31 A;  2NQD B;  3OVZ A;  5EGW A;  2P0R A;  3I3T A;  3OF9 A;  3D6S A;  3IV2 A;  1UKF A;  2GHU A;  4YYU A;  4I04 A;  3BBA A;  1PAD A;  4XUI A;  4QRX A;  3PDF A;  4P6E A;  1YK7 A;  1YK8 A;  2AUZ A;  4XZX A;  1F2B A;  2NQI A;  4FIP A;  3BB7 A;  1CS8 A;  4ZUX U;  2YJ8 A;  4OW0 A;  1VSN A;  3C0R A;  2BDL A;  4PT5 A;  3N3K A;  1NL6 A;  3H7D A;  2CB5 A;  4I07 A;  1MHW A;  2XU1 A;  2B1M A;  3HWN A;  4MM3 B;  2C0Y A;  2R9O A;  3V6C A;  3WXF A;  2YJ2 A;  1AU0 A;  4BSQ A;  2DOS A;  3E9S A;  3BC3 A;  2CIO A;  1O0E A;  4WUR A;  4MI7 A;  4AXM A;  2BTW A;  1CQD A;  4R3D A;  7PCK A;  2FO5 A;  4FK5 A;  4BOQ A;  4D8E A;  1BY8 A;  3IOQ A;  2VHS A;  3M99 A;  4N8W A;  1DKI A;  4D8B A;  3NHE A;  4OEL A;  4W5C A;  1STF E;  2DCD A;  4PI3 A;  3PSE A;  5EZS A;  4YYW A;  3PRM A;  1MDW A;  2Y5B A;  4ZTB A;  2NQA A;  1MEG A;  2AGA A;  5KO3 A;  1AYV A;  4REZ A;  2E00 A;  9PAP A;  5CHV A;  1QXP A;  4OEM A;  2JQG R;  1CSB B;  4YV8 A;  4BOP A;  2DJF B;  3KX1 A;  1EWL A;  4KLB A;  3I06 A;  4MZS A;  2DC9 A;  4AXL A;  3ERV A;  2BDZ A;  2GFO A;  3KSE A;  4Q8G A;  3PBH A;  2R9M A;  3P5W A;  2YJC A;  2E03 A;  2WBF X;  4BPV A;  3BOW A;  2ATO A;  4M0W A;  4P6G A;  5EZQ A;  1KHP A;  1ITO A;  1U5I A;  4OVZ B;  1EF7 A;  4BS6 A;  3OF8 A;  3PHW A;  4N4Z A;  4W5B A;  3HHI A;  1CVZ A;  4XR7 A;  2DCB A;  1YVB A;  2JQF R;  3RNV A;  4BS5 A;  2OZ2 A;  3U8E A;  1TLO A;  3LFY A;  3W30 A;  2YJB A;  4PAD A;  3K8U A;  1AYW A;  4DMY A;  1KFX L;  1VJV A;  1CTE A;  3PRP A;  2HD5 A;  4MZO A;  4X6J A;  3O1G A;  3AI8 A;  3MTV A;  3H89 A;  3KWZ A;  2R9C A;  1PPD A;  2F7D A;  1DF0 A;  2DC8 A;  3MOR A;  3KKU A;  1AU2 A;  1AEC A;  2G8E A;  4QBB A;  1BP4 A;  4YYS A; 
#chains in the Genus database with same CATH homology
 2ARY A;  2Y6E A;  4PP2 E;  2HXZ A;  1X9Y A;  3RVW A;  1KXR A;  1AU4 A;  3CH2 X;  1GEC E;  3S3R A;  3BPF A;  3P5X A;  3WXE A;  2DC7 A;  3IMA A;  2YJ9 A;  3KW9 A;  2FTD A;  5CVM A;  4YYQ A;  2FRQ A;  2DZY A;  3D9W A;  2DCC A;  1HUC B;  1YAL A;  2AYN A;  1FH0 A;  4X6H A;  4GUZ A;  3USV A;  5CVO B;  4W4U A;  1EWP A;  2IPP B;  3P5V A;  4K7C A;  2P7U A;  1AIM A;  1S4V A;  4HWY A;  1SP4 B;  5PAD A;  1EWO A;  2OUL A;  1BQI A;  1IWD A;  2FYE A;  1DEU A;  2DC6 A;  1TU6 A;  3H8B A;  3WXG A;  1CV8 A;  2NQG A;  2PNS A;  1A6R A;  4MSX A;  1PE6 A;  3GCB A;  1NPZ A;  1PBH A;  2P86 A;  2FT2 A;  1GLO A;  2AVW A;  2G8J A;  2VFB A;  3IEJ A;  3QSD A;  1MEM A;  1JQP A;  3KFQ A;  1ZCM A;  1W6F A;  3RVV A;  4CDD B;  3PNR A;  2HH5 A;  3QJ3 A;  4YYV A;  4NV7 A;  4YYR A;  1QMY A;  2FRA A;  1NLJ A;  1F29 A;  2O6X A;  1F2A A;  2DCA A;  1NB3 A;  4YVA A;  5EF4 A;  2AUX A;  4X6I A;  1KHQ A;  3MHS A;  2G7Y A;  3BCN A;  4WA6 A;  1ICF A;  2PAD A;  4BQV A;  3HD3 A;  8PCH A;  3K24 A;  2R9F A;  3H8C A;  5JH3 A;  3CBK A;  2E01 A;  3QT4 A;  5J94 A;  2R9N A;  1NQC A;  2H7J A;  4NV8 A;  1BGO A;  1MIR A;  3N3G A;  4C5P A;  3MTN A;  4PP1 A;  4CZW A;  1NB5 A;  4QH6 A;  1U9X A;  3MHH A;  3E1Z B;  2FQ9 A;  1ATK A;  1PCI A;  4G54 A;  4QRV A;  3P5U A;  5JA7 A;  1PIP A;  3BPM A;  5A24 A;  3DF0 A;  2PBH A;  4CDF B;  6PAD A;  2B1N A;  3B79 A;  1CPJ A;  1M6D A;  2E02 A;  2ACT A;  4CDE B;  2XU3 A;  3O0U A;  1K3B B;  2R6N A;  5CVN B;  5F02 A;  2XU5 A;  3N4C A;  1AYU A;  4FJC A;  1AU3 A;  1E2T A;  1THE A;  1GX3 A;  4RY2 A;  5K16 A;  1ZIV A;  1U9Q X;  3OVX A;  3K9M A;  1PPN A;  2VHF A;  1Y4H A;  3PW3 A;  3IUT A;  4N79 A;  4DMX A;  1Q6K A;  1MS6 A;  3F75 A;  4I05 A;  2DJG B;  2IBI A;  2AIM A;  3KWB X;  2AS8 A;  1Y08 A;  2F1G A;  4BGF A;  1POP A;  1EWM A;  3IHP A;  3V6E A;  1F2C A;  1W5R A;  3LXS A;  4CDC B;  2AYO A;  3TNX A;  1QDQ A;  2HHN A;  3CBJ A;  1GMY A;  3ZUA A;  1PXV A;  3OIS A;  3C9E A;  1TL9 A;  5CHT A;  3S3Q A;  3BWK A;  1ME3 A;  1CJL A;  1ME4 A;  2XU4 A;  2DZZ A;  3HHA A;  5FPW A;  1PPO A;  1GCB A;  3F5V A;  1QOL A;  4Q8H A;  1U9W A;  2PRE A;  1KFU L;  1U9V A;  3RVX A;  1XKG A;  1YT7 A;  2AU1 A;  3H6S A;  4QRG A;  3CH3 X;  2G6D A;  1CB5 A;  1PPP A;  2OP3 A;  2FUD A;  1SNK A;  2NQD B;  3OVZ A;  5EGW A;  2P0R A;  3I3T A;  3OF9 A;  3D6S A;  3IV2 A;  4YYU A;  2GHU A;  4I04 A;  1PAD A;  4XUI A;  4QRX A;  3PDF A;  4P6E A;  1YK7 A;  1YK8 A;  2AUZ A;  1F2B A;  2NQI A;  4FIP A;  1CS8 A;  4ZUX U;  2YJ8 A;  1VSN A;  2BDL A;  3N3K A;  1NL6 A;  3H7D A;  2CB5 A;  4I07 A;  1MHW A;  2XU1 A;  2B1M A;  3HWN A;  2C0Y A;  2R9O A;  3V6C A;  3WXF A;  2YJ2 A;  1AU0 A;  4BSQ A;  3BC3 A;  2CIO A;  1O0E A;  4AXM A;  1CQD A;  7PCK A;  2FO5 A;  4FK5 A;  2VFC A;  1BY8 A;  3IOQ A;  4B55 A;  2VHS A;  3M99 A;  2BSZ A;  4N8W A;  3NHE A;  4OEL A;  4W5C A;  1STF E;  2DCD A;  4PI3 A;  4YYW A;  1MDW A;  3LTW A;  2Y5B A;  2NQA A;  1MEG A;  1AYV A;  2E00 A;  9PAP A;  5CHV A;  1QXP A;  4OEM A;  2JQG R;  1CSB B;  4YV8 A;  2DJF B;  3KX1 A;  1EWL A;  4KLB A;  3I06 A;  4MZS A;  2DC9 A;  4AXL A;  3ERV A;  2BDZ A;  2GFO A;  3KSE A;  4Q8G A;  3PBH A;  2R9M A;  3P5W A;  2YJC A;  2E03 A;  2WBF X;  4BPV A;  3BOW A;  2ATO A;  4P6G A;  1KHP A;  1ITO A;  1U5I A;  1EF7 A;  4BS6 A;  3OF8 A;  4N4Z A;  4W5B A;  3HHI A;  1CVZ A;  4XR7 A;  2DCB A;  1YVB A;  2JQF R;  4BS5 A;  2OZ2 A;  3U8E A;  1TLO A;  3LFY A;  2YJB A;  4PAD A;  3K8U A;  1AYW A;  4DMY A;  1KFX L;  1VJV A;  1CTE A;  2HD5 A;  4MZO A;  4X6J A;  3O1G A;  3AI8 A;  3H89 A;  1W4T A;  3KWZ A;  2R9C A;  1PPD A;  2F7D A;  1DF0 A;  2DC8 A;  3MOR A;  3KKU A;  1AU2 A;  1AEC A;  2G8E A;  4QBB A;  1BP4 A;  4YYS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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