3HHIA

Crystal structure of cathepsin b from t. brucei in complex with ca074
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
258
structure length
258
Chain Sequence
SILPKRRFTEEEARAPLPSSFDSAEAWPNCPTIPQIADQSACGSCWAVAAASAMSDRFCTMGGVQDVHISAGDLLACCSDCGDGCNGGDPDRAWAYFSSTGLVSDYCQPYPFPHCSHHSKSKNGYPPCSQFNFDTPKCDYTCDDPTIPVVNYRSWTSYALQGEDDYMRELFFRGPFEVAFDVYEDFIAYNSGVYHHVSGQYLGGHAVRLVGWGTSNGVPYWKIANSWNTEWGMDGYFLIRRGSSECGIEDGGSAGIPL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures of TbCatB and rhodesain, potential chemotherapeutic targets and major cysteine proteases of Trypanosoma brucei
pubmed doi rcsb
molecule tags Hydrolase
source organism Trypanosoma brucei
molecule keywords Cathepsin B-like cysteine protease
total genus 74
structure length 258
sequence length 258
chains with identical sequence B
ec nomenclature ec 3.4.22.-:
pdb deposition date 2009-05-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 3hhiA00
5J94A 4CDCB 3BCNA 4QRXA 3BPMA 1YT7A 1ME4A 1Y08A 2DC8A 3H89A 5F02A 4G54A 4YYUA 4P6GA 3V6CA 4MSXA 1PPNA 1XKGA 3BC3A 3V6EA 2XU4A 1GMYA 5EGWA 3WXEA 1M6DA 1SNKA 3RVXA 2DC6A 2BDZA 2B1MA 3MTNA 1MEMA 4MZSA 2PREA 3WXGA 3QT4A 1F2AA 2DC7A 5CHVA 4CDEB 3S3QA 3H8CA 3F5VA 2JQFR 1KHQA 2AVWA 2DZZA 2C0YA 4W5CA 3AI8A 1QDQA 1AIMA 1CB5A 2AS8A 4MZOA 3MHSA 3CH3X 3QSDA 2FO5A 4W5BA 2FRQA 2FYEA 2NQIA 2P7UA 2IPPB 1ZIVA 3K9MA 1YK8A 1U5IA 3H8BA 3TNXA 1NB3A 2NQDB 2E01A 3KFQA 5EF4A 2R9CA 4BQVA 1TU6A 1MS6A 4OEMA 3PNRA 2OP3A 2ARYA 1SP4B 1CV8A 2OULA 1PE6A 2E03A 4N79A 4FK5A 4W4UA 2R6NA 1PPOA 1PBHA 4I04A 1AU4A 2H7JA 2E00A 5PADA 2AYNA 4YYRA 1KHPA 3HHAA 3O1GA 1NLJA 2O6XA 3D6SA 4PP1A 1GCBA 3KX1A 1AYVA 3CBKA 2F7DA 1FH0A 1YVBA 3RVVA 4QH6A 4BS6A 2G7YA 1BY8A 4N8WA 2WBFX 2P0RA 4WA6A 1PPDA 2HH5A 2FT2A 2HXZA 3PDFA 4YYVA 1JQPA 5FPWA 3K24A 2DZYA 3OVXA 1U9QX 3IOQA 3N3KA 3N3GA 2R9OA 2OZ2A 2AU1A 1F2BA 3B79A 3CH2X 4PADA 1EF7A 2AUXA 1F29A 4CDFB 4I05A 4KLBA 3NHEA 2P86A 7PCKA 4BS5A 4BPVA 3OISA 4HWYA 3QJ3A 2FRAA 1Y4HA 4ZUXU 3IMAA 2JQGR 4X6IA 3MHHA 1YK7A 3OF9A 4QBBA 1IWDA 1PXVA 3KWZA 3WXFA 1QXPA 2DJGB 1QOLA 2DJFB 1EWMA 3MORA 1VSNA 3USVA 2FTDA 4CZWA 2F1GA 2R9FA 4YYQA 3HD3A 3OF8A 3I3TA 5K16A 4N4ZA 3LFYA 3ERVA 5CVNB 1QMYA 3LXSA 2GHUA 1BGOA 1Q6KA 1HUCB 1ICFA 1KFXL 1S4VA 3H6SA 2XU5A 2VHSA 2CB5A 3IUTA 4YYSA 1BQIA 3ZUAA 3KSEA 2FQ9A 3OVZA 2NQGA 1DF0A 3CBJA 3P5WA 3I06A 1TL9A 2YJ2A 4Q8GA 3PBHA 2Y5BA 3F75A 3U8EA 3RVWA 1CJLA 1KXRA 1THEA 2XU3A 4RY2A 3E1ZB 1O0EA 2IBIA 2FUDA 4PP2E 6PADA 1ATKA 3DF0A 4PI3A 1NB5A 5JH3A 1AU3A 2BDLA 1GECE 1CTEA 3KW9A 3PW3A 2G8JA 1X9YA 1CS8A 4K7CA 1U9VA 2GFOA 1DEUA 2B1NA 3P5VA 1NQCA 5JA7A 4AXLA 2R9MA 3C9EA 2YJCA 1CPJA 2NQAA 1CQDA 3IEJA 5CVMA 1ITOA 4OELA 2YJ8A 1A6RA 3GCBA 1K3BB 8PCHA 1PCIA 1ZCMA 1ME3A 3BOWA 2DCCA 1MEGA 2AUZA 2VHFA 3BWKA 2Y6EA 4DMYA 2DC9A 1BP4A 1YALA 3S3RA 4FIPA 4QRVA 1MDWA 1U9XA 4X6HA 4BSQA 2ATOA 2DCBA 1AECA 1PIPA 3M99A 4Q8HA 1CVZA 3HWNA 2DCAA 5CHTA 4YV8A 1CSBB 2YJ9A 3P5UA 2PNSA 2G8EA 3N4CA 1U9WA 1TLOA 1EWPA 2CIOA 1AU0A 5CVOB 4YYWA 2HD5A 1AYWA 2HHNA 1EWOA 4CDDB 1POPA 1EWLA 2DCDA 1NL6A 1AYUA 4XUIA 4DMXA 3K8UA 3P5XA 4QRGA 2G6DA 4AXMA 3IHPA 1PPPA 1MIRA 2XU1A 3HHIA 5A24A 2ACTA 1PADA 4X6JA 2R9NA 1AU2A 1VJVA 1NPZA 3O0UA 2PADA 3KWBX 2AIMA 4XR7A 4P6EA 2YJBA 1STFE 2PBHA 4YVAA 9PAPA 1KFUL 3BPFA 3H7DA 2E02A 1GLOA 3IV2A 3KKUA 4I07A 1MHWA 2AYOA 4FJCA 1F2CA
chains in the Genus database with same CATH superfamily
5J94A 4CDCB 3BCNA 4QRXA 3BPMA 1YT7A 1ME4A 3TRKA 1Y08A 2DC8A 3H89A 2FE8A 5F02A 4G54A 4YYUA 4P6GA 3V6CA 4MSXA 1PPNA 1XKGA 3BC3A 4REZA 3V6EA 2Z84A 4R3DA 2XU4A 5JZEA 1GMYA 5EGWA 3WXEA 1M6DA 1SNKA 3RVXA 2DC6A 3ZNHA 2BDZA 2B1MA 3MTNA 1MEMA 2BTWA 4MZSA 2PREA 3TMPA 3WXGA 4IP3A 3QT4A 1F2AA 2DC7A 5CHVA 4CDEB 3S3QA 3H8CA 3BBAA 3F5VA 2JQFR 1KHQA 2AVWA 2DZZA 2C0YA 4W5CA 3AI8A 1QDQA 1AIMA 1CB5A 2AS8A 4MZOA 3MHSA 3CH3X 3QSDA 2FO5A 4W5BA 2FRQA 4RF0A 2FYEA 4BOUA 2NQIA 4PT5A 4BOQA 2P7UA 2IPPB 1ZIVA 3K9MA 1YK8A 1U5IA 3H8BA 3TNXA 1NB3A 2NQDB 2E01A 2J7QA 3KFQA 4A5UA 5EF4A 2R9CA 4BQVA 1TU6A 2UZJA 4BOZA 4IUMA 1MS6A 4OEMA 3PNRA 2OP3A 2ARYA 1SP4B 1CV8A 2OULA 1PE6A 2E03A 2JRIA 4N79A 4FK5A 4W4UA 2R6NA 1PPOA 1PBHA 4I04A 1AU4A 2H7JA 2E00A 5PADA 2AYNA 4YYRA 1KHPA 3HHAA 3O1GA 1NLJA 2O6XA 3D6SA 4PP1A 1GCBA 3KX1A 1AYVA 3CBKA 2F7DA 4RKXA 1FH0A 1YVBA 3RVVA 3B21A 4QH6A 4BS6A 2G7YA 1BY8A 4N8WA 2WBFX 3BB7A 2P0RA 4WA6A 1PPDA 2HH5A 2FT2A 2HXZA 3PDFA 4YYVA 1JQPA 5FPWA 4MM3B 4D8BA 3K24A 2DZYA 3OVXA 1U9QX 3IOQA 3N3KA 3N3GA 2R9OA 2OZ2A 2AU1A 1F2BA 3B79A 3CH2X 4PADA 1EF7A 3IFUA 2AUXA 1F29A 4CDFB 2BU3A 4I05A 4KLBA 3NHEA 2P86A 7PCKA 4BS5A 4BPVA 3RNVA 3OISA 4HWYA 3QJ3A 4GUAA 2FRAA 1Y4HA 4ZUXU 3IMAA 2JQGR 4X6IA 3MHHA 1YK7A 3OF9A 4QBBA 1IWDA 3MJ5A 1PXVA 3KWZA 4MI7A 1UKFA 3WXFA 1QXPA 2DJGB 1QOLA 2DJFB 1EWMA 3MORA 1VSNA 3USVA 2FTDA 4CZWA 4HXDB 2F1GA 2R9FA 4OVZB 4YYQA 3HD3A 3OF8A 3I3TA 5K16A 5EZQA 4N4ZA 3LFYA 3ERVA 5CVNB 1QMYA 3LXSA 2GHUA 1BGOA 1Q6KA 1HUCB 1ICFA 3PT2A 1KFXL 1S4VA 3H6SA 2XU5A 1DKIA 2VHSA 2CB5A 3IUTA 4YYSA 1BQIA 3ZUAA 3OQCA 3KSEA 2FQ9A 3OVZA 2NQGA 1DF0A 3CBJA 3PRPA 3P5WA 3I06A 4XZXA 1TL9A 2YJ2A 4Q8GA 3PBHA 2Y5BA 3F75A 3U8EA 3RVWA 1CJLA 1KXRA 1THEA 2XU3A 4RY2A 3E1ZB 1O0EA 4D8IA 2IBIA 2FUDA 4PP2E 6PADA 1ATKA 3DF0A 4PI3A 1NB5A 5JH3A 1AU3A 2BDLA 3E9SA 1GECE 1CTEA 3KW9A 3PW3A 2G8JA 1X9YA 2BTWB 1CS8A 4K7CA 1U9VA 2GFOA 1DEUA 2B1NA 3P5VA 1NQCA 5JA7A 3PSEA 4AXLA 3PHUA 2R9MA 3C9EA 2YJCA 1CPJA 2NQAA 1CQDA 3IEJA 5CVMA 1ITOA 4OELA 2YJ8A 1A6RA 4D8EA 3GCBA 1K3BB 8PCHA 3PHXA 1PCIA 1ZCMA 1ME3A 4P16A 3BOWA 2JTCA 2DCCA 1MEGA 2AUZA 3O65A 2VHFA 3BWKA 3W31A 3BY4A 4RNAA 2Y6EA 4DMYA 2DC9A 4OW0A 1BP4A 1YZBA 1YALA 4WURA 3S3RA 4FIPA 4QRVA 1MDWA 1U9XA 4X6HA 3MTVA 4BSQA 2ATOA 4BOSA 2DCBA 1AECA 1PIPA 3M99A 4Q8HA 1CVZA 3HWNA 2DCAA 5CHTA 4YV8A 1CSBB 2YJ9A 3P5UA 2PNSA 2G8EA 3N4CA 1U9WA 1TLOA 4M0WA 1EWPA 2CIOA 1AU0A 5CVOB 4BOPA 4YYWA 2HD5A 1AYWA 2HHNA 1EWOA 4CDDB 1POPA 1EWLA 2DCDA 1NL6A 1AYUA 2HWKA 4XUIA 4DMXA 3K8UA 4ZTBA 3P5XA 5KO3A 4QRGA 2G6DA 4AXMA 3IHPA 2AGAA 3W30A 1PPPA 4RF1A 1MIRA 2XU1A 3HHIA 5A24A 2ACTA 1PVJA 1PADA 4X6JA 2R9NA 3C0RA 2J7QC 3MP2A 1AU2A 1VJVA 1NPZA 3PHWA 3O0UA 2PADA 3KWBX 2AIMA 4XR7A 4P6EA 2YJBA 5EZSA 1STFE 4OVZA 2PBHA 4YVAA 9PAPA 1KFUL 3BPFA 3H7DA 2E02A 2DOSA 1GLOA 3IV2A 3KKUA 5E6JA 4I07A 3PRMA 1MHWA 2AYOA 4FJCA 1F2CA
chains in the Genus database with same CATH topology
5J94A 4CDCB 3BCNA 4QRXA 3BPMA 1YT7A 1ME4A 1Y08A 2DC8A 3H89A 5F02A 4G54A 4YYUA 4P6GA 3V6CA 4MSXA 1PPNA 1XKGA 3BC3A 3LTWA 3V6EA 2XU4A 1GMYA 5EGWA 3WXEA 1M6DA 1SNKA 3RVXA 2DC6A 2BDZA 2B1MA 3MTNA 1MEMA 4MZSA 2PREA 3WXGA 3QT4A 3D9WA 1F2AA 2DC7A 5CHVA 4CDEB 3S3QA 3H8CA 3F5VA 2JQFR 1KHQA 2AVWA 2DZZA 2C0YA 4W5CA 3AI8A 1QDQA 1AIMA 1CB5A 2AS8A 4MZOA 3MHSA 3CH3X 3QSDA 2FO5A 4W5BA 2FRQA 2FYEA 2NQIA 2P7UA 2IPPB 1ZIVA 3K9MA 1YK8A 1U5IA 3H8BA 3TNXA 1NB3A 2NQDB 2E01A 4B55A 3KFQA 5EF4A 2R9CA 4BQVA 1TU6A 1MS6A 4OEMA 3PNRA 2OP3A 2ARYA 1SP4B 1CV8A 2OULA 1PE6A 2E03A 4N79A 4FK5A 4W4UA 2R6NA 1PPOA 1PBHA 4I04A 1AU4A 2H7JA 2E00A 5PADA 2AYNA 4YYRA 1KHPA 3HHAA 3O1GA 1NLJA 2O6XA 3D6SA 4PP1A 1GCBA 2BSZA 3KX1A 1AYVA 3CBKA 2F7DA 4BGFA 1W6FA 1FH0A 1YVBA 3RVVA 4QH6A 4BS6A 2G7YA 1BY8A 4N8WA 2WBFX 2P0RA 4WA6A 1PPDA 4GUZA 2HH5A 2FT2A 2HXZA 3PDFA 4YYVA 1JQPA 5FPWA 3K24A 2DZYA 3OVXA 1U9QX 3IOQA 3N3KA 3N3GA 2R9OA 2OZ2A 2AU1A 1F2BA 2VFBA 3B79A 3CH2X 4PADA 1EF7A 2AUXA 1F29A 4CDFB 4I05A 4KLBA 3NHEA 2P86A 7PCKA 4BS5A 4BPVA 3OISA 4HWYA 3QJ3A 2FRAA 1Y4HA 4ZUXU 3IMAA 2JQGR 4X6IA 3MHHA 1YK7A 3OF9A 4QBBA 1IWDA 1PXVA 3KWZA 3WXFA 1QXPA 2DJGB 1QOLA 2DJFB 1EWMA 3MORA 1VSNA 4NV7A 3USVA 2FTDA 4CZWA 2F1GA 2R9FA 4YYQA 3HD3A 3OF8A 3I3TA 5K16A 4N4ZA 3LFYA 3ERVA 5CVNB 1QMYA 3LXSA 2GHUA 1BGOA 1Q6KA 1HUCB 1ICFA 1KFXL 1S4VA 3H6SA 2XU5A 2VHSA 2CB5A 3IUTA 4YYSA 1BQIA 3ZUAA 3KSEA 2FQ9A 3OVZA 2NQGA 1DF0A 3CBJA 3P5WA 3I06A 1TL9A 2YJ2A 4Q8GA 3PBHA 2Y5BA 3F75A 3U8EA 3RVWA 1CJLA 1KXRA 1THEA 2XU3A 4RY2A 3E1ZB 1O0EA 2IBIA 2FUDA 4PP2E 6PADA 1ATKA 3DF0A 4PI3A 1NB5A 5JH3A 1AU3A 2BDLA 1GECE 1CTEA 1E2TA 3KW9A 3PW3A 2G8JA 1X9YA 1CS8A 4K7CA 1U9VA 2GFOA 1DEUA 2B1NA 3P5VA 1NQCA 5JA7A 4AXLA 2R9MA 3C9EA 2YJCA 1CPJA 2NQAA 1CQDA 3IEJA 5CVMA 1ITOA 4OELA 2YJ8A 1A6RA 3GCBA 1K3BB 8PCHA 1PCIA 1ZCMA 1ME3A 3BOWA 2DCCA 1MEGA 2AUZA 2VHFA 3BWKA 1W5RA 2Y6EA 4DMYA 2DC9A 1BP4A 1YALA 3S3RA 4FIPA 4QRVA 1MDWA 1U9XA 4X6HA 4C5PA 4BSQA 2ATOA 2DCBA 1AECA 1PIPA 3M99A 4Q8HA 1CVZA 3HWNA 2DCAA 5CHTA 4YV8A 1CSBB 2YJ9A 3P5UA 1GX3A 2PNSA 2G8EA 3N4CA 1U9WA 1TLOA 1EWPA 2CIOA 1AU0A 5CVOB 4YYWA 2HD5A 1AYWA 2HHNA 1EWOA 4CDDB 1POPA 1W4TA 1EWLA 2VFCA 2DCDA 1NL6A 1AYUA 4XUIA 4DMXA 3K8UA 3P5XA 4QRGA 2G6DA 4AXMA 3IHPA 1PPPA 1MIRA 2XU1A 3HHIA 5A24A 2ACTA 1PADA 4X6JA 4NV8A 2R9NA 1AU2A 1VJVA 1NPZA 3O0UA 2PADA 3KWBX 2AIMA 4XR7A 4P6EA 2YJBA 1STFE 2PBHA 4YVAA 9PAPA 1KFUL 3BPFA 3H7DA 2E02A 1GLOA 3IV2A 3KKUA 4I07A 1MHWA 2AYOA 4FJCA 1F2CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5J94 A;  4CDC B;  3BCN A;  4QRX A;  3BPM A;  1YT7 A;  1ME4 A;  1Y08 A;  2DC8 A;  3H89 A;  5F02 A;  4G54 A;  4YYU A;  4P6G A;  3V6C A;  4MSX A;  1PPN A;  1XKG A;  3BC3 A;  3V6E A;  2XU4 A;  1GMY A;  5EGW A;  3WXE A;  1M6D A;  1SNK A;  3RVX A;  2DC6 A;  2BDZ A;  2B1M A;  3MTN A;  1MEM A;  4MZS A;  2PRE A;  3WXG A;  3QT4 A;  1F2A A;  2DC7 A;  5CHV A;  4CDE B;  3S3Q A;  3H8C A;  3F5V A;  2JQF R;  1KHQ A;  2AVW A;  2DZZ A;  2C0Y A;  4W5C A;  3AI8 A;  1QDQ A;  1AIM A;  1CB5 A;  2AS8 A;  4MZO A;  3MHS A;  3CH3 X;  3QSD A;  2FO5 A;  4W5B A;  2FRQ A;  2FYE A;  2NQI A;  2P7U A;  2IPP B;  1ZIV A;  3K9M A;  1YK8 A;  1U5I A;  3H8B A;  3TNX A;  1NB3 A;  2NQD B;  2E01 A;  3KFQ A;  5EF4 A;  2R9C A;  4BQV A;  1TU6 A;  1MS6 A;  4OEM A;  3PNR A;  2OP3 A;  2ARY A;  1SP4 B;  1CV8 A;  2OUL A;  1PE6 A;  2E03 A;  4N79 A;  4FK5 A;  4W4U A;  2R6N A;  1PPO A;  1PBH A;  4I04 A;  1AU4 A;  2H7J A;  2E00 A;  5PAD A;  2AYN A;  4YYR A;  1KHP A;  3HHA A;  3O1G A;  1NLJ A;  2O6X A;  3D6S A;  4PP1 A;  1GCB A;  3KX1 A;  1AYV A;  3CBK A;  2F7D A;  1FH0 A;  1YVB A;  3RVV A;  4QH6 A;  4BS6 A;  2G7Y A;  1BY8 A;  4N8W A;  2WBF X;  2P0R A;  4WA6 A;  1PPD A;  2HH5 A;  2FT2 A;  2HXZ A;  3PDF A;  4YYV A;  1JQP A;  5FPW A;  3K24 A;  2DZY A;  3OVX A;  1U9Q X;  3IOQ A;  3N3K A;  3N3G A;  2R9O A;  2OZ2 A;  2AU1 A;  1F2B A;  3B79 A;  3CH2 X;  4PAD A;  1EF7 A;  2AUX A;  1F29 A;  4CDF B;  4I05 A;  4KLB A;  3NHE A;  2P86 A;  7PCK A;  4BS5 A;  4BPV A;  3OIS A;  4HWY A;  3QJ3 A;  2FRA A;  1Y4H A;  4ZUX U;  3IMA A;  2JQG R;  4X6I A;  3MHH A;  1YK7 A;  3OF9 A;  4QBB A;  1IWD A;  1PXV A;  3KWZ A;  3WXF A;  1QXP A;  2DJG B;  1QOL A;  2DJF B;  1EWM A;  3MOR A;  1VSN A;  3USV A;  2FTD A;  4CZW A;  2F1G A;  2R9F A;  4YYQ A;  3HD3 A;  3OF8 A;  3I3T A;  5K16 A;  4N4Z A;  3LFY A;  3ERV A;  5CVN B;  1QMY A;  3LXS A;  2GHU A;  1BGO A;  1Q6K A;  1HUC B;  1ICF A;  1KFX L;  1S4V A;  3H6S A;  2XU5 A;  2VHS A;  2CB5 A;  3IUT A;  4YYS A;  1BQI A;  3ZUA A;  3KSE A;  2FQ9 A;  3OVZ A;  2NQG A;  1DF0 A;  3CBJ A;  3P5W A;  3I06 A;  1TL9 A;  2YJ2 A;  4Q8G A;  3PBH A;  2Y5B A;  3F75 A;  3U8E A;  3RVW A;  1CJL A;  1KXR A;  1THE A;  2XU3 A;  4RY2 A;  3E1Z B;  1O0E A;  2IBI A;  2FUD A;  4PP2 E;  6PAD A;  1ATK A;  3DF0 A;  4PI3 A;  1NB5 A;  5JH3 A;  1AU3 A;  2BDL A;  1GEC E;  1CTE A;  3KW9 A;  3PW3 A;  2G8J A;  1X9Y A;  1CS8 A;  4K7C A;  1U9V A;  2GFO A;  1DEU A;  2B1N A;  3P5V A;  1NQC A;  5JA7 A;  4AXL A;  2R9M A;  3C9E A;  2YJC A;  1CPJ A;  2NQA A;  1CQD A;  3IEJ A;  5CVM A;  1ITO A;  4OEL A;  2YJ8 A;  1A6R A;  3GCB A;  1K3B B;  8PCH A;  1PCI A;  1ZCM A;  1ME3 A;  3BOW A;  2DCC A;  1MEG A;  2AUZ A;  2VHF A;  3BWK A;  2Y6E A;  4DMY A;  2DC9 A;  1BP4 A;  1YAL A;  3S3R A;  4FIP A;  4QRV A;  1MDW A;  1U9X A;  4X6H A;  4BSQ A;  2ATO A;  2DCB A;  1AEC A;  1PIP A;  3M99 A;  4Q8H A;  1CVZ A;  3HWN A;  2DCA A;  5CHT A;  4YV8 A;  1CSB B;  2YJ9 A;  3P5U A;  2PNS A;  2G8E A;  3N4C A;  1U9W A;  1TLO A;  1EWP A;  2CIO A;  1AU0 A;  5CVO B;  4YYW A;  2HD5 A;  1AYW A;  2HHN A;  1EWO A;  4CDD B;  1POP A;  1EWL A;  2DCD A;  1NL6 A;  1AYU A;  4XUI A;  4DMX A;  3K8U A;  3P5X A;  4QRG A;  2G6D A;  4AXM A;  3IHP A;  1PPP A;  1MIR A;  2XU1 A;  3HHI A;  5A24 A;  2ACT A;  1PAD A;  4X6J A;  2R9N A;  1AU2 A;  1VJV A;  1NPZ A;  3O0U A;  2PAD A;  3KWB X;  2AIM A;  4XR7 A;  4P6E A;  2YJB A;  1STF E;  2PBH A;  4YVA A;  9PAP A;  1KFU L;  3BPF A;  3H7D A;  2E02 A;  1GLO A;  3IV2 A;  3KKU A;  4I07 A;  1MHW A;  2AYO A;  4FJC A;  1F2C A; 
#chains in the Genus database with same CATH topology
 5J94 A;  4CDC B;  3BCN A;  4QRX A;  3BPM A;  1YT7 A;  1ME4 A;  3TRK A;  1Y08 A;  2DC8 A;  3H89 A;  2FE8 A;  5F02 A;  4G54 A;  4YYU A;  4P6G A;  3V6C A;  4MSX A;  1PPN A;  1XKG A;  3BC3 A;  4REZ A;  3V6E A;  2Z84 A;  4R3D A;  2XU4 A;  5JZE A;  1GMY A;  5EGW A;  3WXE A;  1M6D A;  1SNK A;  3RVX A;  2DC6 A;  3ZNH A;  2BDZ A;  2B1M A;  3MTN A;  1MEM A;  2BTW A;  4MZS A;  2PRE A;  3TMP A;  3WXG A;  4IP3 A;  3QT4 A;  1F2A A;  2DC7 A;  5CHV A;  4CDE B;  3S3Q A;  3H8C A;  3BBA A;  3F5V A;  2JQF R;  1KHQ A;  2AVW A;  2DZZ A;  2C0Y A;  4W5C A;  3AI8 A;  1QDQ A;  1AIM A;  1CB5 A;  2AS8 A;  4MZO A;  3MHS A;  3CH3 X;  3QSD A;  2FO5 A;  4W5B A;  2FRQ A;  4RF0 A;  2FYE A;  4BOU A;  2NQI A;  4PT5 A;  4BOQ A;  2P7U A;  2IPP B;  1ZIV A;  3K9M A;  1YK8 A;  1U5I A;  3H8B A;  3TNX A;  1NB3 A;  2NQD B;  2E01 A;  2J7Q A;  3KFQ A;  4A5U A;  5EF4 A;  2R9C A;  4BQV A;  1TU6 A;  2UZJ A;  4BOZ A;  4IUM A;  1MS6 A;  4OEM A;  3PNR A;  2OP3 A;  2ARY A;  1SP4 B;  1CV8 A;  2OUL A;  1PE6 A;  2E03 A;  2JRI A;  4N79 A;  4FK5 A;  4W4U A;  2R6N A;  1PPO A;  1PBH A;  4I04 A;  1AU4 A;  2H7J A;  2E00 A;  5PAD A;  2AYN A;  4YYR A;  1KHP A;  3HHA A;  3O1G A;  1NLJ A;  2O6X A;  3D6S A;  4PP1 A;  1GCB A;  3KX1 A;  1AYV A;  3CBK A;  2F7D A;  4RKX A;  1FH0 A;  1YVB A;  3RVV A;  3B21 A;  4QH6 A;  4BS6 A;  2G7Y A;  1BY8 A;  4N8W A;  2WBF X;  3BB7 A;  2P0R A;  4WA6 A;  1PPD A;  2HH5 A;  2FT2 A;  2HXZ A;  3PDF A;  4YYV A;  1JQP A;  5FPW A;  4MM3 B;  4D8B A;  3K24 A;  2DZY A;  3OVX A;  1U9Q X;  3IOQ A;  3N3K A;  3N3G A;  2R9O A;  2OZ2 A;  2AU1 A;  1F2B A;  3B79 A;  3CH2 X;  4PAD A;  1EF7 A;  3IFU A;  2AUX A;  1F29 A;  4CDF B;  2BU3 A;  4I05 A;  4KLB A;  3NHE A;  2P86 A;  7PCK A;  4BS5 A;  4BPV A;  3RNV A;  3OIS A;  4HWY A;  3QJ3 A;  4GUA A;  2FRA A;  1Y4H A;  4ZUX U;  3IMA A;  2JQG R;  4X6I A;  3MHH A;  1YK7 A;  3OF9 A;  4QBB A;  1IWD A;  3MJ5 A;  1PXV A;  3KWZ A;  4MI7 A;  1UKF A;  3WXF A;  1QXP A;  2DJG B;  1QOL A;  2DJF B;  1EWM A;  3MOR A;  1VSN A;  3USV A;  2FTD A;  4CZW A;  4HXD B;  2F1G A;  2R9F A;  4OVZ B;  4YYQ A;  3HD3 A;  3OF8 A;  3I3T A;  5K16 A;  5EZQ A;  4N4Z A;  3LFY A;  3ERV A;  5CVN B;  1QMY A;  3LXS A;  2GHU A;  1BGO A;  1Q6K A;  1HUC B;  1ICF A;  3PT2 A;  1KFX L;  1S4V A;  3H6S A;  2XU5 A;  1DKI A;  2VHS A;  2CB5 A;  3IUT A;  4YYS A;  1BQI A;  3ZUA A;  3OQC A;  3KSE A;  2FQ9 A;  3OVZ A;  2NQG A;  1DF0 A;  3CBJ A;  3PRP A;  3P5W A;  3I06 A;  4XZX A;  1TL9 A;  2YJ2 A;  4Q8G A;  3PBH A;  2Y5B A;  3F75 A;  3U8E A;  3RVW A;  1CJL A;  1KXR A;  1THE A;  2XU3 A;  4RY2 A;  3E1Z B;  1O0E A;  4D8I A;  2IBI A;  2FUD A;  4PP2 E;  6PAD A;  1ATK A;  3DF0 A;  4PI3 A;  1NB5 A;  5JH3 A;  1AU3 A;  2BDL A;  3E9S A;  1GEC E;  1CTE A;  3KW9 A;  3PW3 A;  2G8J A;  1X9Y A;  2BTW B;  1CS8 A;  4K7C A;  1U9V A;  2GFO A;  1DEU A;  2B1N A;  3P5V A;  1NQC A;  5JA7 A;  3PSE A;  4AXL A;  3PHU A;  2R9M A;  3C9E A;  2YJC A;  1CPJ A;  2NQA A;  1CQD A;  3IEJ A;  5CVM A;  1ITO A;  4OEL A;  2YJ8 A;  1A6R A;  4D8E A;  3GCB A;  1K3B B;  8PCH A;  3PHX A;  1PCI A;  1ZCM A;  1ME3 A;  4P16 A;  3BOW A;  2JTC A;  2DCC A;  1MEG A;  2AUZ A;  3O65 A;  2VHF A;  3BWK A;  3W31 A;  3BY4 A;  4RNA A;  2Y6E A;  4DMY A;  2DC9 A;  4OW0 A;  1BP4 A;  1YZB A;  1YAL A;  4WUR A;  3S3R A;  4FIP A;  4QRV A;  1MDW A;  1U9X A;  4X6H A;  3MTV A;  4BSQ A;  2ATO A;  4BOS A;  2DCB A;  1AEC A;  1PIP A;  3M99 A;  4Q8H A;  1CVZ A;  3HWN A;  2DCA A;  5CHT A;  4YV8 A;  1CSB B;  2YJ9 A;  3P5U A;  2PNS A;  2G8E A;  3N4C A;  1U9W A;  1TLO A;  4M0W A;  1EWP A;  2CIO A;  1AU0 A;  5CVO B;  4BOP A;  4YYW A;  2HD5 A;  1AYW A;  2HHN A;  1EWO A;  4CDD B;  1POP A;  1EWL A;  2DCD A;  1NL6 A;  1AYU A;  2HWK A;  4XUI A;  4DMX A;  3K8U A;  4ZTB A;  3P5X A;  5KO3 A;  4QRG A;  2G6D A;  4AXM A;  3IHP A;  2AGA A;  3W30 A;  1PPP A;  4RF1 A;  1MIR A;  2XU1 A;  3HHI A;  5A24 A;  2ACT A;  1PVJ A;  1PAD A;  4X6J A;  2R9N A;  3C0R A;  2J7Q C;  3MP2 A;  1AU2 A;  1VJV A;  1NPZ A;  3PHW A;  3O0U A;  2PAD A;  3KWB X;  2AIM A;  4XR7 A;  4P6E A;  2YJB A;  5EZS A;  1STF E;  4OVZ A;  2PBH A;  4YVA A;  9PAP A;  1KFU L;  3BPF A;  3H7D A;  2E02 A;  2DOS A;  1GLO A;  3IV2 A;  3KKU A;  5E6J A;  4I07 A;  3PRM A;  1MHW A;  2AYO A;  4FJC A;  1F2C A; 
#chains in the Genus database with same CATH homology
 5J94 A;  4CDC B;  3BCN A;  4QRX A;  3BPM A;  1YT7 A;  1ME4 A;  1Y08 A;  2DC8 A;  3H89 A;  5F02 A;  4G54 A;  4YYU A;  4P6G A;  3V6C A;  4MSX A;  1PPN A;  1XKG A;  3BC3 A;  3LTW A;  3V6E A;  2XU4 A;  1GMY A;  5EGW A;  3WXE A;  1M6D A;  1SNK A;  3RVX A;  2DC6 A;  2BDZ A;  2B1M A;  3MTN A;  1MEM A;  4MZS A;  2PRE A;  3WXG A;  3QT4 A;  3D9W A;  1F2A A;  2DC7 A;  5CHV A;  4CDE B;  3S3Q A;  3H8C A;  3F5V A;  2JQF R;  1KHQ A;  2AVW A;  2DZZ A;  2C0Y A;  4W5C A;  3AI8 A;  1QDQ A;  1AIM A;  1CB5 A;  2AS8 A;  4MZO A;  3MHS A;  3CH3 X;  3QSD A;  2FO5 A;  4W5B A;  2FRQ A;  2FYE A;  2NQI A;  2P7U A;  2IPP B;  1ZIV A;  3K9M A;  1YK8 A;  1U5I A;  3H8B A;  3TNX A;  1NB3 A;  2NQD B;  2E01 A;  4B55 A;  3KFQ A;  5EF4 A;  2R9C A;  4BQV A;  1TU6 A;  1MS6 A;  4OEM A;  3PNR A;  2OP3 A;  2ARY A;  1SP4 B;  1CV8 A;  2OUL A;  1PE6 A;  2E03 A;  4N79 A;  4FK5 A;  4W4U A;  2R6N A;  1PPO A;  1PBH A;  4I04 A;  1AU4 A;  2H7J A;  2E00 A;  5PAD A;  2AYN A;  4YYR A;  1KHP A;  3HHA A;  3O1G A;  1NLJ A;  2O6X A;  3D6S A;  4PP1 A;  1GCB A;  2BSZ A;  3KX1 A;  1AYV A;  3CBK A;  2F7D A;  4BGF A;  1W6F A;  1FH0 A;  1YVB A;  3RVV A;  4QH6 A;  4BS6 A;  2G7Y A;  1BY8 A;  4N8W A;  2WBF X;  2P0R A;  4WA6 A;  1PPD A;  4GUZ A;  2HH5 A;  2FT2 A;  2HXZ A;  3PDF A;  4YYV A;  1JQP A;  5FPW A;  3K24 A;  2DZY A;  3OVX A;  1U9Q X;  3IOQ A;  3N3K A;  3N3G A;  2R9O A;  2OZ2 A;  2AU1 A;  1F2B A;  2VFB A;  3B79 A;  3CH2 X;  4PAD A;  1EF7 A;  2AUX A;  1F29 A;  4CDF B;  4I05 A;  4KLB A;  3NHE A;  2P86 A;  7PCK A;  4BS5 A;  4BPV A;  3OIS A;  4HWY A;  3QJ3 A;  2FRA A;  1Y4H A;  4ZUX U;  3IMA A;  2JQG R;  4X6I A;  3MHH A;  1YK7 A;  3OF9 A;  4QBB A;  1IWD A;  1PXV A;  3KWZ A;  3WXF A;  1QXP A;  2DJG B;  1QOL A;  2DJF B;  1EWM A;  3MOR A;  1VSN A;  4NV7 A;  3USV A;  2FTD A;  4CZW A;  2F1G A;  2R9F A;  4YYQ A;  3HD3 A;  3OF8 A;  3I3T A;  5K16 A;  4N4Z A;  3LFY A;  3ERV A;  5CVN B;  1QMY A;  3LXS A;  2GHU A;  1BGO A;  1Q6K A;  1HUC B;  1ICF A;  1KFX L;  1S4V A;  3H6S A;  2XU5 A;  2VHS A;  2CB5 A;  3IUT A;  4YYS A;  1BQI A;  3ZUA A;  3KSE A;  2FQ9 A;  3OVZ A;  2NQG A;  1DF0 A;  3CBJ A;  3P5W A;  3I06 A;  1TL9 A;  2YJ2 A;  4Q8G A;  3PBH A;  2Y5B A;  3F75 A;  3U8E A;  3RVW A;  1CJL A;  1KXR A;  1THE A;  2XU3 A;  4RY2 A;  3E1Z B;  1O0E A;  2IBI A;  2FUD A;  4PP2 E;  6PAD A;  1ATK A;  3DF0 A;  4PI3 A;  1NB5 A;  5JH3 A;  1AU3 A;  2BDL A;  1GEC E;  1CTE A;  1E2T A;  3KW9 A;  3PW3 A;  2G8J A;  1X9Y A;  1CS8 A;  4K7C A;  1U9V A;  2GFO A;  1DEU A;  2B1N A;  3P5V A;  1NQC A;  5JA7 A;  4AXL A;  2R9M A;  3C9E A;  2YJC A;  1CPJ A;  2NQA A;  1CQD A;  3IEJ A;  5CVM A;  1ITO A;  4OEL A;  2YJ8 A;  1A6R A;  3GCB A;  1K3B B;  8PCH A;  1PCI A;  1ZCM A;  1ME3 A;  3BOW A;  2DCC A;  1MEG A;  2AUZ A;  2VHF A;  3BWK A;  1W5R A;  2Y6E A;  4DMY A;  2DC9 A;  1BP4 A;  1YAL A;  3S3R A;  4FIP A;  4QRV A;  1MDW A;  1U9X A;  4X6H A;  4C5P A;  4BSQ A;  2ATO A;  2DCB A;  1AEC A;  1PIP A;  3M99 A;  4Q8H A;  1CVZ A;  3HWN A;  2DCA A;  5CHT A;  4YV8 A;  1CSB B;  2YJ9 A;  3P5U A;  1GX3 A;  2PNS A;  2G8E A;  3N4C A;  1U9W A;  1TLO A;  1EWP A;  2CIO A;  1AU0 A;  5CVO B;  4YYW A;  2HD5 A;  1AYW A;  2HHN A;  1EWO A;  4CDD B;  1POP A;  1W4T A;  1EWL A;  2VFC A;  2DCD A;  1NL6 A;  1AYU A;  4XUI A;  4DMX A;  3K8U A;  3P5X A;  4QRG A;  2G6D A;  4AXM A;  3IHP A;  1PPP A;  1MIR A;  2XU1 A;  3HHI A;  5A24 A;  2ACT A;  1PAD A;  4X6J A;  4NV8 A;  2R9N A;  1AU2 A;  1VJV A;  1NPZ A;  3O0U A;  2PAD A;  3KWB X;  2AIM A;  4XR7 A;  4P6E A;  2YJB A;  1STF E;  2PBH A;  4YVA A;  9PAP A;  1KFU L;  3BPF A;  3H7D A;  2E02 A;  1GLO A;  3IV2 A;  3KKU A;  4I07 A;  1MHW A;  2AYO A;  4FJC A;  1F2C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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