3H8BA

A combined crystallographic and molecular dynamics study of cathepsin-l retro-binding inhibitors(compound 9)
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
220
structure length
215
Chain Sequence
APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A combined crystallographic and molecular dynamics study of cathepsin L retrobinding inhibitors
pubmed doi rcsb
molecule keywords Cathepsin L1
molecule tags Hydrolase
source organism Homo sapiens
total genus 64
structure length 215
sequence length 220
chains with identical sequence B, C, D, E, F
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2009-04-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 3h8bA00
5EGWA 1CV8A 1MIRA 2AUXA 2DZYA 4G54A 7PCKA 3H7DA 4I05A 3OVZA 2C0YA 2P0RA 2FRQA 4YVAA 2FUDA 1GLOA 2R9NA 1AU0A 4K7CA 3I3TA 3KFQA 4FJCA 2VHFA 3CBJA 1PBHA 1CS8A 4FK5A 2E02A 3BCNA 4BQVA 4BS5A 1GCBA 3USVA 4AXLA 1NPZA 2OP3A 2XU5A 3V6EA 5JA7A 1DEUA 3KSEA 4I04A 3F5VA 3PNRA 4P6EA 1PPDA 2E00A 1KHQA 8PCHA 1XKGA 2DZZA 3LFYA 3OVXA 3BWKA 2Y6EA 5CVOB 3H89A 4OEMA 2GFOA 2CIOA 2OZ2A 4BPVA 9PAPA 3OF8A 1NLJA 1CB5A 1JQPA 4CZWA 4N4ZA 1FH0A 1NQCA 3IEJA 2P86A 3AI8A 4XUIA 2XU4A 4QRVA 4YYVA 2E03A 1U9VA 4YYWA 1YT7A 3OF9A 1QOLA 3P5XA 1KXRA 3CH3X 1U9XA 4Q8GA 3QSDA 1PPOA 3D6SA 4HWYA 2WBFX 3P5WA 2G8EA 3P5VA 4YV8A 4PP2E 3K8UA 1ME3A 2PNSA 1EWMA 2NQDB 2AUZA 4WA6A 2DCDA 2G8JA 3BOWA 5CHTA 3N3GA 2ATOA 4QRXA 5PADA 2GHUA 5A24A 3TNXA 3IV2A 3IOQA 1AYWA 3KWZA 1MEMA 4CDDB 1NB3A 1VJVA 3H8CA 3K24A 2FRAA 1QXPA 1CQDA 4CDCB 3NHEA 4YYRA 1AIMA 2FYEA 2AYNA 1CTEA 1HUCB 4CDEB 1PPNA 2DCAA 4YYSA 3CH2X 2FQ9A 4Q8HA 1DF0A 1EF7A 4OELA 2PREA 1MHWA 2HXZA 2F7DA 1CSBB 4X6HA 4W4UA 3KKUA 3BPMA 3IHPA 2HD5A 2NQGA 1PCIA 3F75A 4DMYA 2ARYA 3RVVA 1ZIVA 3RVXA 2G6DA 2BDZA 1K3BB 3HD3A 4ZUXU 3V6CA 2IBIA 1AYUA 3HHIA 3MTNA 1VSNA 1THEA 5K16A 3PDFA 1MEGA 3GCBA 4PI3A 3O1GA 5EF4A 1PIPA 3HHAA 4I07A 4YYUA 1MDWA 2YJ9A 2B1NA 1CVZA 2DC7A 3S3QA 2AYOA 1ME4A 2YJ2A 1Y4HA 2AVWA 1TLOA 3S3RA 1PPPA 2DC8A 1BP4A 1F2BA 2HHNA 1ITOA 4BSQA 1M6DA 2ACTA 2PADA 4YYQA 1U9WA 1ICFA 3PW3A 3MORA 2JQFR 2DJFB 1YVBA 3OISA 2B1MA 3KW9A 2VHSA 6PADA 2R9CA 1GMYA 4RY2A 3O0UA 1NL6A 1S4VA 1AYVA 3C9EA 2CB5A 2F1GA 1F2CA 1STFE 3E1ZB 4BS6A 2JQGR 3WXGA 1KFUL 2R9FA 1EWLA 2XU3A 4CDFB 3I06A 1CJLA 1EWOA 1AU2A 1YK7A 2AS8A 4N8WA 2FO5A 1ATKA 2YJBA 3IUTA 1O0EA 5JH3A 2NQAA 4QH6A 2Y5BA 1ZCMA 4PP1A 4P6GA 1PADA 1YALA 1X9YA 4QBBA 2P7UA 2E01A 3P5UA 1U5IA 3CBKA 3HWNA 3RVWA 4X6IA 3QT4A 5CHVA 3ZUAA 1A6RA 1QMYA 2HH5A 1CPJA 1F2AA 4MZOA 2R9OA 1PE6A 1AU3A 2AIMA 3H8BA 3MHHA 3WXFA 2OULA 3IMAA 3LXSA 1BGOA 4QRGA 3N4CA 3WXEA 2DCBA 3KX1A 3BPFA 2BDLA 1U9QX 2H7JA 1KFXL 4KLBA 2DC6A 3MHSA 1PXVA 2YJCA 1AU4A 4PADA 1KHPA 2DCCA 5F02A 5J94A 1NB5A 5FPWA 3QJ3A 2O6XA 4MSXA 4W5CA 1POPA 2R6NA 4X6JA 1SNKA 4W5BA 3H6SA 2IPPB 4FIPA 1EWPA 3KWBX 5CVNB 4DMXA 3ERVA 5CVMA 2R9MA 3K9MA 2FTDA 1Y08A 2DJGB 2AU1A 2YJ8A 3B79A 1Q6KA 1F29A 2FT2A 1IWDA 2NQIA 2DC9A 3PBHA 4XR7A 2XU1A 3M99A 2PBHA 1GECE 1AECA 4MZSA 1BQIA 1QDQA 1BY8A 1TU6A 4AXMA 1MS6A 4N79A 3DF0A 2G7YA 3BC3A 3N3KA 3U8EA 1YK8A 1TL9A 1SP4B
chains in the Genus database with same CATH superfamily
5EGWA 1CV8A 1MIRA 3PHWA 2AUXA 2DZYA 4G54A 7PCKA 3H7DA 3PRMA 4I05A 3OVZA 2C0YA 2P0RA 2FRQA 4BOQA 4YVAA 2FUDA 1GLOA 2R9NA 2UZJA 3PHUA 1AU0A 4PT5A 4K7CA 3I3TA 3KFQA 4FJCA 2VHFA 3CBJA 1PBHA 1CS8A 4FK5A 2E02A 3BCNA 4BQVA 4BS5A 1GCBA 3USVA 4AXLA 1NPZA 2DOSA 2OP3A 2XU5A 3V6EA 5JA7A 1DEUA 4MI7A 3KSEA 4I04A 3F5VA 3PNRA 4P6EA 1PPDA 4RKXA 2E00A 1KHQA 3BBAA 8PCHA 1XKGA 2DZZA 3LFYA 3OVXA 3E9SA 3BWKA 2Y6EA 5CVOB 3H89A 4OEMA 2GFOA 2CIOA 2OZ2A 4BPVA 9PAPA 3OF8A 1NLJA 4IP3A 1CB5A 1JQPA 4CZWA 4N4ZA 1FH0A 4M0WA 1DKIA 1NQCA 1YZBA 3IEJA 2P86A 3AI8A 4XUIA 2XU4A 4QRVA 4YYVA 2E03A 1U9VA 4YYWA 1YT7A 3OF9A 1QOLA 3P5XA 1KXRA 3CH3X 1U9XA 4Q8GA 3QSDA 1PPOA 3D6SA 4HWYA 2WBFX 3P5WA 2G8EA 3P5VA 4YV8A 4PP2E 3K8UA 1ME3A 2PNSA 1EWMA 2NQDB 3IFUA 2AUZA 4WA6A 2DCDA 2G8JA 3BOWA 1PVJA 5CHTA 2Z84A 3N3GA 2ATOA 4QRXA 5PADA 2GHUA 5A24A 3TNXA 3IV2A 3IOQA 1AYWA 3KWZA 1MEMA 4CDDB 1NB3A 1VJVA 3H8CA 3K24A 2FRAA 1QXPA 1CQDA 4CDCB 3NHEA 4YYRA 1AIMA 2FYEA 2AYNA 1CTEA 1HUCB 4CDEB 1PPNA 2DCAA 4YYSA 3CH2X 2FQ9A 3TRKA 4Q8HA 1DF0A 1EF7A 4OELA 2PREA 4XZXA 1MHWA 2HXZA 2F7DA 1CSBB 4X6HA 4W4UA 3KKUA 3BPMA 3IHPA 2HD5A 2NQGA 1PCIA 3F75A 3OQCA 4ZTBA 2J7QA 4DMYA 2ARYA 3RVVA 1ZIVA 3RVXA 2G6DA 2BDZA 1K3BB 3HD3A 1UKFA 4ZUXU 4RNAA 3V6CA 2IBIA 1AYUA 3HHIA 3MTNA 1VSNA 1THEA 5K16A 3PDFA 1MEGA 3PHXA 4RF0A 3GCBA 4D8IA 3O1GA 4PI3A 5EF4A 1PIPA 3W30A 3HHAA 4I07A 4IUMA 4YYUA 1MDWA 2YJ9A 2B1NA 1CVZA 2DC7A 3S3QA 2AYOA 1ME4A 5EZQA 2YJ2A 1Y4HA 2AVWA 1TLOA 3S3RA 1PPPA 5EZSA 2DC8A 1BP4A 1F2BA 2HHNA 1ITOA 4P16A 4BSQA 4R3DA 1M6DA 4BOSA 2ACTA 3W31A 2HWKA 2PADA 4YYQA 1U9WA 1ICFA 3PW3A 3MJ5A 3MORA 2JQFR 2DJFB 1YVBA 3OISA 2B1MA 3KW9A 2VHSA 4BOZA 6PADA 2R9CA 1GMYA 4RY2A 3O0UA 4OVZA 4A5UA 1NL6A 1S4VA 1AYVA 4BOUA 3C9EA 2CB5A 2F1GA 1F2CA 4GUAA 1STFE 3E1ZB 4BS6A 2JQGR 3WXGA 1KFUL 2R9FA 1EWLA 2XU3A 4OW0A 4OVZB 4CDFB 3I06A 4WURA 1CJLA 1EWOA 1AU2A 4D8EA 1YK7A 2AS8A 4N8WA 2FO5A 1ATKA 2YJBA 3IUTA 1O0EA 5JH3A 5E6JA 2JTCA 2NQAA 4QH6A 2Y5BA 1ZCMA 2AGAA 4PP1A 3PSEA 4P6GA 1PADA 1YALA 1X9YA 3MP2A 4QBBA 2P7UA 3PT2A 2E01A 3P5UA 1U5IA 3CBKA 3HWNA 3RVWA 2J7QC 3C0RA 4X6IA 3RNVA 3TMPA 4BOPA 3QT4A 5CHVA 3ZUAA 1A6RA 1QMYA 2HH5A 1CPJA 1F2AA 4MZOA 2R9OA 1PE6A 1AU3A 2AIMA 3H8BA 3MHHA 3WXFA 2OULA 3IMAA 3LXSA 1BGOA 4QRGA 3N4CA 3WXEA 3BY4A 2DCBA 3KX1A 3BPFA 2BDLA 1U9QX 2H7JA 4D8BA 1KFXL 4KLBA 2DC6A 2BTWA 3MHSA 1PXVA 2YJCA 1AU4A 4PADA 1KHPA 2DCCA 5F02A 5J94A 1NB5A 2FE8A 5FPWA 3BB7A 5JZEA 3QJ3A 2O6XA 4MSXA 4W5CA 1POPA 2R6NA 3O65A 4X6JA 3ZNHA 1SNKA 4W5BA 3H6SA 2IPPB 4FIPA 2BTWB 1EWPA 3KWBX 5CVNB 4DMXA 3ERVA 5CVMA 4MM3B 3PRPA 2R9MA 3K9MA 2FTDA 1Y08A 2DJGB 5KO3A 3MTVA 2AU1A 2YJ8A 3B79A 1Q6KA 1F29A 2FT2A 1IWDA 2NQIA 2DC9A 3PBHA 4HXDB 4XR7A 2XU1A 3M99A 4REZA 2PBHA 2JRIA 1GECE 4RF1A 1AECA 4MZSA 1BQIA 1QDQA 1BY8A 3B21A 1TU6A 4AXMA 1MS6A 4N79A 3DF0A 2BU3A 2G7YA 3BC3A 3N3KA 3U8EA 1YK8A 1TL9A 1SP4B
chains in the Genus database with same CATH topology
5EGWA 1CV8A 1MIRA 2AUXA 2DZYA 4G54A 7PCKA 3H7DA 4I05A 3OVZA 2C0YA 2P0RA 2FRQA 4YVAA 2FUDA 1GLOA 2R9NA 1AU0A 4K7CA 3I3TA 3KFQA 4FJCA 2VHFA 3CBJA 1PBHA 1CS8A 4FK5A 2E02A 3BCNA 4BQVA 4BS5A 1GCBA 1W4TA 3USVA 4AXLA 1NPZA 2VFCA 2OP3A 2XU5A 3V6EA 5JA7A 1DEUA 3KSEA 4I04A 3F5VA 3PNRA 4P6EA 1PPDA 2E00A 1KHQA 8PCHA 1XKGA 2DZZA 3LFYA 3OVXA 4BGFA 3BWKA 2Y6EA 5CVOB 3H89A 4OEMA 2GFOA 2CIOA 2OZ2A 4BPVA 9PAPA 3OF8A 1NLJA 1CB5A 1JQPA 4CZWA 4N4ZA 1FH0A 1NQCA 3IEJA 2P86A 3AI8A 4XUIA 2XU4A 4QRVA 4YYVA 2BSZA 2E03A 1U9VA 4YYWA 1YT7A 3OF9A 1QOLA 3LTWA 3P5XA 1KXRA 3CH3X 1U9XA 4Q8GA 3QSDA 1PPOA 3D6SA 4HWYA 2WBFX 3P5WA 2G8EA 3P5VA 4YV8A 4PP2E 3K8UA 1ME3A 2PNSA 1EWMA 2NQDB 2AUZA 4WA6A 2DCDA 2G8JA 3BOWA 5CHTA 3N3GA 2ATOA 4QRXA 5PADA 1W6FA 2GHUA 5A24A 3TNXA 3IV2A 3IOQA 1AYWA 3KWZA 1MEMA 4CDDB 1NB3A 1VJVA 3H8CA 3K24A 2FRAA 1QXPA 1CQDA 4CDCB 3NHEA 4YYRA 1AIMA 2FYEA 2AYNA 1CTEA 1HUCB 4CDEB 1PPNA 2DCAA 4YYSA 3CH2X 2FQ9A 4Q8HA 1DF0A 1EF7A 4OELA 2PREA 1MHWA 2HXZA 1W5RA 1CSBB 2F7DA 4X6HA 4W4UA 3KKUA 3BPMA 3IHPA 2HD5A 2NQGA 1PCIA 3F75A 4DMYA 2ARYA 3RVVA 1ZIVA 3RVXA 1E2TA 2G6DA 2BDZA 2VFBA 1K3BB 3HD3A 4ZUXU 3V6CA 2IBIA 1AYUA 3HHIA 3MTNA 1VSNA 1THEA 5K16A 3PDFA 1MEGA 1GX3A 3GCBA 3O1GA 4PI3A 5EF4A 1PIPA 3HHAA 4I07A 4YYUA 1MDWA 2YJ9A 2B1NA 1CVZA 2DC7A 3S3QA 2AYOA 1ME4A 2YJ2A 1Y4HA 2AVWA 1TLOA 3S3RA 1PPPA 2DC8A 1BP4A 1F2BA 2HHNA 1ITOA 4BSQA 4NV7A 1M6DA 2ACTA 2PADA 4YYQA 1U9WA 1ICFA 3PW3A 3MORA 4NV8A 2JQFR 2DJFB 1YVBA 3OISA 2B1MA 3KW9A 2VHSA 6PADA 2R9CA 1GMYA 4RY2A 3O0UA 1NL6A 1S4VA 1AYVA 3C9EA 2CB5A 2F1GA 1F2CA 1STFE 3E1ZB 4BS6A 2JQGR 3WXGA 1KFUL 2R9FA 1EWLA 2XU3A 4CDFB 3I06A 1CJLA 1EWOA 1AU2A 3D9WA 1YK7A 2AS8A 4N8WA 2FO5A 1ATKA 2YJBA 3IUTA 1O0EA 5JH3A 2NQAA 4QH6A 2Y5BA 1ZCMA 4PP1A 4P6GA 1PADA 1YALA 1X9YA 4QBBA 2P7UA 2E01A 3P5UA 1U5IA 3CBKA 3HWNA 4B55A 3RVWA 4X6IA 4GUZA 3QT4A 5CHVA 3ZUAA 1A6RA 1QMYA 2HH5A 1CPJA 1F2AA 4MZOA 2R9OA 1PE6A 1AU3A 2AIMA 3H8BA 3MHHA 3WXFA 2OULA 3IMAA 3LXSA 1BGOA 4QRGA 3N4CA 3WXEA 2DCBA 3KX1A 3BPFA 2BDLA 1U9QX 2H7JA 1KFXL 4KLBA 2DC6A 3MHSA 1PXVA 2YJCA 1AU4A 4PADA 1KHPA 2DCCA 5F02A 5J94A 1NB5A 5FPWA 3QJ3A 2O6XA 4MSXA 4W5CA 1POPA 2R6NA 4X6JA 1SNKA 4W5BA 3H6SA 2IPPB 4FIPA 1EWPA 3KWBX 5CVNB 4DMXA 3ERVA 5CVMA 2R9MA 3K9MA 2FTDA 1Y08A 2DJGB 4C5PA 2AU1A 2YJ8A 3B79A 1Q6KA 1F29A 2FT2A 1IWDA 2NQIA 2DC9A 3PBHA 4XR7A 2XU1A 3M99A 2PBHA 1GECE 1AECA 4MZSA 1BQIA 1QDQA 1BY8A 1TU6A 4AXMA 1MS6A 4N79A 3DF0A 2G7YA 3BC3A 3N3KA 3U8EA 1YK8A 1TL9A 1SP4B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5EGW A;  1CV8 A;  1MIR A;  2AUX A;  2DZY A;  4G54 A;  7PCK A;  3H7D A;  4I05 A;  3OVZ A;  2C0Y A;  2P0R A;  2FRQ A;  4YVA A;  2FUD A;  1GLO A;  2R9N A;  1AU0 A;  4K7C A;  3I3T A;  3KFQ A;  4FJC A;  2VHF A;  3CBJ A;  1PBH A;  1CS8 A;  4FK5 A;  2E02 A;  3BCN A;  4BQV A;  4BS5 A;  1GCB A;  3USV A;  4AXL A;  1NPZ A;  2OP3 A;  2XU5 A;  3V6E A;  5JA7 A;  1DEU A;  3KSE A;  4I04 A;  3F5V A;  3PNR A;  4P6E A;  1PPD A;  2E00 A;  1KHQ A;  8PCH A;  1XKG A;  2DZZ A;  3LFY A;  3OVX A;  3BWK A;  2Y6E A;  5CVO B;  3H89 A;  4OEM A;  2GFO A;  2CIO A;  2OZ2 A;  4BPV A;  9PAP A;  3OF8 A;  1NLJ A;  1CB5 A;  1JQP A;  4CZW A;  4N4Z A;  1FH0 A;  1NQC A;  3IEJ A;  2P86 A;  3AI8 A;  4XUI A;  2XU4 A;  4QRV A;  4YYV A;  2E03 A;  1U9V A;  4YYW A;  1YT7 A;  3OF9 A;  1QOL A;  3P5X A;  1KXR A;  3CH3 X;  1U9X A;  4Q8G A;  3QSD A;  1PPO A;  3D6S A;  4HWY A;  2WBF X;  3P5W A;  2G8E A;  3P5V A;  4YV8 A;  4PP2 E;  3K8U A;  1ME3 A;  2PNS A;  1EWM A;  2NQD B;  2AUZ A;  4WA6 A;  2DCD A;  2G8J A;  3BOW A;  5CHT A;  3N3G A;  2ATO A;  4QRX A;  5PAD A;  2GHU A;  5A24 A;  3TNX A;  3IV2 A;  3IOQ A;  1AYW A;  3KWZ A;  1MEM A;  4CDD B;  1NB3 A;  1VJV A;  3H8C A;  3K24 A;  2FRA A;  1QXP A;  1CQD A;  4CDC B;  3NHE A;  4YYR A;  1AIM A;  2FYE A;  2AYN A;  1CTE A;  1HUC B;  4CDE B;  1PPN A;  2DCA A;  4YYS A;  3CH2 X;  2FQ9 A;  4Q8H A;  1DF0 A;  1EF7 A;  4OEL A;  2PRE A;  1MHW A;  2HXZ A;  2F7D A;  1CSB B;  4X6H A;  4W4U A;  3KKU A;  3BPM A;  3IHP A;  2HD5 A;  2NQG A;  1PCI A;  3F75 A;  4DMY A;  2ARY A;  3RVV A;  1ZIV A;  3RVX A;  2G6D A;  2BDZ A;  1K3B B;  3HD3 A;  4ZUX U;  3V6C A;  2IBI A;  1AYU A;  3HHI A;  3MTN A;  1VSN A;  1THE A;  5K16 A;  3PDF A;  1MEG A;  3GCB A;  4PI3 A;  3O1G A;  5EF4 A;  1PIP A;  3HHA A;  4I07 A;  4YYU A;  1MDW A;  2YJ9 A;  2B1N A;  1CVZ A;  2DC7 A;  3S3Q A;  2AYO A;  1ME4 A;  2YJ2 A;  1Y4H A;  2AVW A;  1TLO A;  3S3R A;  1PPP A;  2DC8 A;  1BP4 A;  1F2B A;  2HHN A;  1ITO A;  4BSQ A;  1M6D A;  2ACT A;  2PAD A;  4YYQ A;  1U9W A;  1ICF A;  3PW3 A;  3MOR A;  2JQF R;  2DJF B;  1YVB A;  3OIS A;  2B1M A;  3KW9 A;  2VHS A;  6PAD A;  2R9C A;  1GMY A;  4RY2 A;  3O0U A;  1NL6 A;  1S4V A;  1AYV A;  3C9E A;  2CB5 A;  2F1G A;  1F2C A;  1STF E;  3E1Z B;  4BS6 A;  2JQG R;  3WXG A;  1KFU L;  2R9F A;  1EWL A;  2XU3 A;  4CDF B;  3I06 A;  1CJL A;  1EWO A;  1AU2 A;  1YK7 A;  2AS8 A;  4N8W A;  2FO5 A;  1ATK A;  2YJB A;  3IUT A;  1O0E A;  5JH3 A;  2NQA A;  4QH6 A;  2Y5B A;  1ZCM A;  4PP1 A;  4P6G A;  1PAD A;  1YAL A;  1X9Y A;  4QBB A;  2P7U A;  2E01 A;  3P5U A;  1U5I A;  3CBK A;  3HWN A;  3RVW A;  4X6I A;  3QT4 A;  5CHV A;  3ZUA A;  1A6R A;  1QMY A;  2HH5 A;  1CPJ A;  1F2A A;  4MZO A;  2R9O A;  1PE6 A;  1AU3 A;  2AIM A;  3H8B A;  3MHH A;  3WXF A;  2OUL A;  3IMA A;  3LXS A;  1BGO A;  4QRG A;  3N4C A;  3WXE A;  2DCB A;  3KX1 A;  3BPF A;  2BDL A;  1U9Q X;  2H7J A;  1KFX L;  4KLB A;  2DC6 A;  3MHS A;  1PXV A;  2YJC A;  1AU4 A;  4PAD A;  1KHP A;  2DCC A;  5F02 A;  5J94 A;  1NB5 A;  5FPW A;  3QJ3 A;  2O6X A;  4MSX A;  4W5C A;  1POP A;  2R6N A;  4X6J A;  1SNK A;  4W5B A;  3H6S A;  2IPP B;  4FIP A;  1EWP A;  3KWB X;  5CVN B;  4DMX A;  3ERV A;  5CVM A;  2R9M A;  3K9M A;  2FTD A;  1Y08 A;  2DJG B;  2AU1 A;  2YJ8 A;  3B79 A;  1Q6K A;  1F29 A;  2FT2 A;  1IWD A;  2NQI A;  2DC9 A;  3PBH A;  4XR7 A;  2XU1 A;  3M99 A;  2PBH A;  1GEC E;  1AEC A;  4MZS A;  1BQI A;  1QDQ A;  1BY8 A;  1TU6 A;  4AXM A;  1MS6 A;  4N79 A;  3DF0 A;  2G7Y A;  3BC3 A;  3N3K A;  3U8E A;  1YK8 A;  1TL9 A;  1SP4 B; 
#chains in the Genus database with same CATH topology
 5EGW A;  1CV8 A;  1MIR A;  3PHW A;  2AUX A;  2DZY A;  4G54 A;  7PCK A;  3H7D A;  3PRM A;  4I05 A;  3OVZ A;  2C0Y A;  2P0R A;  2FRQ A;  4BOQ A;  4YVA A;  2FUD A;  1GLO A;  2R9N A;  2UZJ A;  3PHU A;  1AU0 A;  4PT5 A;  4K7C A;  3I3T A;  3KFQ A;  4FJC A;  2VHF A;  3CBJ A;  1PBH A;  1CS8 A;  4FK5 A;  2E02 A;  3BCN A;  4BQV A;  4BS5 A;  1GCB A;  3USV A;  4AXL A;  1NPZ A;  2DOS A;  2OP3 A;  2XU5 A;  3V6E A;  5JA7 A;  1DEU A;  4MI7 A;  3KSE A;  4I04 A;  3F5V A;  3PNR A;  4P6E A;  1PPD A;  4RKX A;  2E00 A;  1KHQ A;  3BBA A;  8PCH A;  1XKG A;  2DZZ A;  3LFY A;  3OVX A;  3E9S A;  3BWK A;  2Y6E A;  5CVO B;  3H89 A;  4OEM A;  2GFO A;  2CIO A;  2OZ2 A;  4BPV A;  9PAP A;  3OF8 A;  1NLJ A;  4IP3 A;  1CB5 A;  1JQP A;  4CZW A;  4N4Z A;  1FH0 A;  4M0W A;  1DKI A;  1NQC A;  1YZB A;  3IEJ A;  2P86 A;  3AI8 A;  4XUI A;  2XU4 A;  4QRV A;  4YYV A;  2E03 A;  1U9V A;  4YYW A;  1YT7 A;  3OF9 A;  1QOL A;  3P5X A;  1KXR A;  3CH3 X;  1U9X A;  4Q8G A;  3QSD A;  1PPO A;  3D6S A;  4HWY A;  2WBF X;  3P5W A;  2G8E A;  3P5V A;  4YV8 A;  4PP2 E;  3K8U A;  1ME3 A;  2PNS A;  1EWM A;  2NQD B;  3IFU A;  2AUZ A;  4WA6 A;  2DCD A;  2G8J A;  3BOW A;  1PVJ A;  5CHT A;  2Z84 A;  3N3G A;  2ATO A;  4QRX A;  5PAD A;  2GHU A;  5A24 A;  3TNX A;  3IV2 A;  3IOQ A;  1AYW A;  3KWZ A;  1MEM A;  4CDD B;  1NB3 A;  1VJV A;  3H8C A;  3K24 A;  2FRA A;  1QXP A;  1CQD A;  4CDC B;  3NHE A;  4YYR A;  1AIM A;  2FYE A;  2AYN A;  1CTE A;  1HUC B;  4CDE B;  1PPN A;  2DCA A;  4YYS A;  3CH2 X;  2FQ9 A;  3TRK A;  4Q8H A;  1DF0 A;  1EF7 A;  4OEL A;  2PRE A;  4XZX A;  1MHW A;  2HXZ A;  2F7D A;  1CSB B;  4X6H A;  4W4U A;  3KKU A;  3BPM A;  3IHP A;  2HD5 A;  2NQG A;  1PCI A;  3F75 A;  3OQC A;  4ZTB A;  2J7Q A;  4DMY A;  2ARY A;  3RVV A;  1ZIV A;  3RVX A;  2G6D A;  2BDZ A;  1K3B B;  3HD3 A;  1UKF A;  4ZUX U;  4RNA A;  3V6C A;  2IBI A;  1AYU A;  3HHI A;  3MTN A;  1VSN A;  1THE A;  5K16 A;  3PDF A;  1MEG A;  3PHX A;  4RF0 A;  3GCB A;  4D8I A;  3O1G A;  4PI3 A;  5EF4 A;  1PIP A;  3W30 A;  3HHA A;  4I07 A;  4IUM A;  4YYU A;  1MDW A;  2YJ9 A;  2B1N A;  1CVZ A;  2DC7 A;  3S3Q A;  2AYO A;  1ME4 A;  5EZQ A;  2YJ2 A;  1Y4H A;  2AVW A;  1TLO A;  3S3R A;  1PPP A;  5EZS A;  2DC8 A;  1BP4 A;  1F2B A;  2HHN A;  1ITO A;  4P16 A;  4BSQ A;  4R3D A;  1M6D A;  4BOS A;  2ACT A;  3W31 A;  2HWK A;  2PAD A;  4YYQ A;  1U9W A;  1ICF A;  3PW3 A;  3MJ5 A;  3MOR A;  2JQF R;  2DJF B;  1YVB A;  3OIS A;  2B1M A;  3KW9 A;  2VHS A;  4BOZ A;  6PAD A;  2R9C A;  1GMY A;  4RY2 A;  3O0U A;  4OVZ A;  4A5U A;  1NL6 A;  1S4V A;  1AYV A;  4BOU A;  3C9E A;  2CB5 A;  2F1G A;  1F2C A;  4GUA A;  1STF E;  3E1Z B;  4BS6 A;  2JQG R;  3WXG A;  1KFU L;  2R9F A;  1EWL A;  2XU3 A;  4OW0 A;  4OVZ B;  4CDF B;  3I06 A;  4WUR A;  1CJL A;  1EWO A;  1AU2 A;  4D8E A;  1YK7 A;  2AS8 A;  4N8W A;  2FO5 A;  1ATK A;  2YJB A;  3IUT A;  1O0E A;  5JH3 A;  5E6J A;  2JTC A;  2NQA A;  4QH6 A;  2Y5B A;  1ZCM A;  2AGA A;  4PP1 A;  3PSE A;  4P6G A;  1PAD A;  1YAL A;  1X9Y A;  3MP2 A;  4QBB A;  2P7U A;  3PT2 A;  2E01 A;  3P5U A;  1U5I A;  3CBK A;  3HWN A;  3RVW A;  2J7Q C;  3C0R A;  4X6I A;  3RNV A;  3TMP A;  4BOP A;  3QT4 A;  5CHV A;  3ZUA A;  1A6R A;  1QMY A;  2HH5 A;  1CPJ A;  1F2A A;  4MZO A;  2R9O A;  1PE6 A;  1AU3 A;  2AIM A;  3H8B A;  3MHH A;  3WXF A;  2OUL A;  3IMA A;  3LXS A;  1BGO A;  4QRG A;  3N4C A;  3WXE A;  3BY4 A;  2DCB A;  3KX1 A;  3BPF A;  2BDL A;  1U9Q X;  2H7J A;  4D8B A;  1KFX L;  4KLB A;  2DC6 A;  2BTW A;  3MHS A;  1PXV A;  2YJC A;  1AU4 A;  4PAD A;  1KHP A;  2DCC A;  5F02 A;  5J94 A;  1NB5 A;  2FE8 A;  5FPW A;  3BB7 A;  5JZE A;  3QJ3 A;  2O6X A;  4MSX A;  4W5C A;  1POP A;  2R6N A;  3O65 A;  4X6J A;  3ZNH A;  1SNK A;  4W5B A;  3H6S A;  2IPP B;  4FIP A;  2BTW B;  1EWP A;  3KWB X;  5CVN B;  4DMX A;  3ERV A;  5CVM A;  4MM3 B;  3PRP A;  2R9M A;  3K9M A;  2FTD A;  1Y08 A;  2DJG B;  5KO3 A;  3MTV A;  2AU1 A;  2YJ8 A;  3B79 A;  1Q6K A;  1F29 A;  2FT2 A;  1IWD A;  2NQI A;  2DC9 A;  3PBH A;  4HXD B;  4XR7 A;  2XU1 A;  3M99 A;  4REZ A;  2PBH A;  2JRI A;  1GEC E;  4RF1 A;  1AEC A;  4MZS A;  1BQI A;  1QDQ A;  1BY8 A;  3B21 A;  1TU6 A;  4AXM A;  1MS6 A;  4N79 A;  3DF0 A;  2BU3 A;  2G7Y A;  3BC3 A;  3N3K A;  3U8E A;  1YK8 A;  1TL9 A;  1SP4 B; 
#chains in the Genus database with same CATH homology
 5EGW A;  1CV8 A;  1MIR A;  2AUX A;  2DZY A;  4G54 A;  7PCK A;  3H7D A;  4I05 A;  3OVZ A;  2C0Y A;  2P0R A;  2FRQ A;  4YVA A;  2FUD A;  1GLO A;  2R9N A;  1AU0 A;  4K7C A;  3I3T A;  3KFQ A;  4FJC A;  2VHF A;  3CBJ A;  1PBH A;  1CS8 A;  4FK5 A;  2E02 A;  3BCN A;  4BQV A;  4BS5 A;  1GCB A;  1W4T A;  3USV A;  4AXL A;  1NPZ A;  2VFC A;  2OP3 A;  2XU5 A;  3V6E A;  5JA7 A;  1DEU A;  3KSE A;  4I04 A;  3F5V A;  3PNR A;  4P6E A;  1PPD A;  2E00 A;  1KHQ A;  8PCH A;  1XKG A;  2DZZ A;  3LFY A;  3OVX A;  4BGF A;  3BWK A;  2Y6E A;  5CVO B;  3H89 A;  4OEM A;  2GFO A;  2CIO A;  2OZ2 A;  4BPV A;  9PAP A;  3OF8 A;  1NLJ A;  1CB5 A;  1JQP A;  4CZW A;  4N4Z A;  1FH0 A;  1NQC A;  3IEJ A;  2P86 A;  3AI8 A;  4XUI A;  2XU4 A;  4QRV A;  4YYV A;  2BSZ A;  2E03 A;  1U9V A;  4YYW A;  1YT7 A;  3OF9 A;  1QOL A;  3LTW A;  3P5X A;  1KXR A;  3CH3 X;  1U9X A;  4Q8G A;  3QSD A;  1PPO A;  3D6S A;  4HWY A;  2WBF X;  3P5W A;  2G8E A;  3P5V A;  4YV8 A;  4PP2 E;  3K8U A;  1ME3 A;  2PNS A;  1EWM A;  2NQD B;  2AUZ A;  4WA6 A;  2DCD A;  2G8J A;  3BOW A;  5CHT A;  3N3G A;  2ATO A;  4QRX A;  5PAD A;  1W6F A;  2GHU A;  5A24 A;  3TNX A;  3IV2 A;  3IOQ A;  1AYW A;  3KWZ A;  1MEM A;  4CDD B;  1NB3 A;  1VJV A;  3H8C A;  3K24 A;  2FRA A;  1QXP A;  1CQD A;  4CDC B;  3NHE A;  4YYR A;  1AIM A;  2FYE A;  2AYN A;  1CTE A;  1HUC B;  4CDE B;  1PPN A;  2DCA A;  4YYS A;  3CH2 X;  2FQ9 A;  4Q8H A;  1DF0 A;  1EF7 A;  4OEL A;  2PRE A;  1MHW A;  2HXZ A;  1W5R A;  1CSB B;  2F7D A;  4X6H A;  4W4U A;  3KKU A;  3BPM A;  3IHP A;  2HD5 A;  2NQG A;  1PCI A;  3F75 A;  4DMY A;  2ARY A;  3RVV A;  1ZIV A;  3RVX A;  1E2T A;  2G6D A;  2BDZ A;  2VFB A;  1K3B B;  3HD3 A;  4ZUX U;  3V6C A;  2IBI A;  1AYU A;  3HHI A;  3MTN A;  1VSN A;  1THE A;  5K16 A;  3PDF A;  1MEG A;  1GX3 A;  3GCB A;  3O1G A;  4PI3 A;  5EF4 A;  1PIP A;  3HHA A;  4I07 A;  4YYU A;  1MDW A;  2YJ9 A;  2B1N A;  1CVZ A;  2DC7 A;  3S3Q A;  2AYO A;  1ME4 A;  2YJ2 A;  1Y4H A;  2AVW A;  1TLO A;  3S3R A;  1PPP A;  2DC8 A;  1BP4 A;  1F2B A;  2HHN A;  1ITO A;  4BSQ A;  4NV7 A;  1M6D A;  2ACT A;  2PAD A;  4YYQ A;  1U9W A;  1ICF A;  3PW3 A;  3MOR A;  4NV8 A;  2JQF R;  2DJF B;  1YVB A;  3OIS A;  2B1M A;  3KW9 A;  2VHS A;  6PAD A;  2R9C A;  1GMY A;  4RY2 A;  3O0U A;  1NL6 A;  1S4V A;  1AYV A;  3C9E A;  2CB5 A;  2F1G A;  1F2C A;  1STF E;  3E1Z B;  4BS6 A;  2JQG R;  3WXG A;  1KFU L;  2R9F A;  1EWL A;  2XU3 A;  4CDF B;  3I06 A;  1CJL A;  1EWO A;  1AU2 A;  3D9W A;  1YK7 A;  2AS8 A;  4N8W A;  2FO5 A;  1ATK A;  2YJB A;  3IUT A;  1O0E A;  5JH3 A;  2NQA A;  4QH6 A;  2Y5B A;  1ZCM A;  4PP1 A;  4P6G A;  1PAD A;  1YAL A;  1X9Y A;  4QBB A;  2P7U A;  2E01 A;  3P5U A;  1U5I A;  3CBK A;  3HWN A;  4B55 A;  3RVW A;  4X6I A;  4GUZ A;  3QT4 A;  5CHV A;  3ZUA A;  1A6R A;  1QMY A;  2HH5 A;  1CPJ A;  1F2A A;  4MZO A;  2R9O A;  1PE6 A;  1AU3 A;  2AIM A;  3H8B A;  3MHH A;  3WXF A;  2OUL A;  3IMA A;  3LXS A;  1BGO A;  4QRG A;  3N4C A;  3WXE A;  2DCB A;  3KX1 A;  3BPF A;  2BDL A;  1U9Q X;  2H7J A;  1KFX L;  4KLB A;  2DC6 A;  3MHS A;  1PXV A;  2YJC A;  1AU4 A;  4PAD A;  1KHP A;  2DCC A;  5F02 A;  5J94 A;  1NB5 A;  5FPW A;  3QJ3 A;  2O6X A;  4MSX A;  4W5C A;  1POP A;  2R6N A;  4X6J A;  1SNK A;  4W5B A;  3H6S A;  2IPP B;  4FIP A;  1EWP A;  3KWB X;  5CVN B;  4DMX A;  3ERV A;  5CVM A;  2R9M A;  3K9M A;  2FTD A;  1Y08 A;  2DJG B;  4C5P A;  2AU1 A;  2YJ8 A;  3B79 A;  1Q6K A;  1F29 A;  2FT2 A;  1IWD A;  2NQI A;  2DC9 A;  3PBH A;  4XR7 A;  2XU1 A;  3M99 A;  2PBH A;  1GEC E;  1AEC A;  4MZS A;  1BQI A;  1QDQ A;  1BY8 A;  1TU6 A;  4AXM A;  1MS6 A;  4N79 A;  3DF0 A;  2G7Y A;  3BC3 A;  3N3K A;  3U8E A;  1YK8 A;  1TL9 A;  1SP4 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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