4YVAA

Cathepsin k co-crystallized with actinomycetes extract
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
213
structure length
213
Chain Sequence
DSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Affinity Crystallography: A New Approach to Extracting High-Affinity Enzyme Inhibitors from Natural Extracts.
pubmed doi rcsb
molecule keywords Cathepsin K
molecule tags Hydrolase
source organism Homo sapiens
total genus 63
structure length 213
sequence length 213
ec nomenclature ec 3.4.22.38: Cathepsin K.
pdb deposition date 2015-03-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 4yvaA00
3K8UA 1ME3A 4MSXA 2DJGB 2NQIA 1YK7A 5EGWA 3IEJA 1XKGA 4ZUXU 3U8EA 4Q8HA 4YYVA 1Q6KA 5A24A 3KX1A 1AYWA 1STFE 1K3BB 3P5XA 1TLOA 4W4UA 1AECA 4HWYA 2HD5A 3BPMA 2G8JA 1CSBB 5PADA 2FRQA 4W5BA 3K9MA 1CS8A 2AIMA 1YT7A 1F2AA 1F2CA 1GMYA 2DZYA 3WXFA 1F29A 2DCCA 3WXEA 2DJFB 1TL9A 3V6EA 3TNXA 3OISA 4QH6A 8PCHA 3BC3A 4FIPA 1KFUL 4XR7A 2FTDA 1MEMA 1U5IA 1GLOA 1JQPA 4PP2E 2E00A 4I07A 1BP4A 4CDEB 1QDQA 1YVBA 3IUTA 1EWPA 3PDFA 2R9CA 4QRXA 3M99A 3CBJA 4BS6A 1M6DA 2E01A 2DCBA 2GHUA 4N8WA 2FO5A 1POPA 1IWDA 2AS8A 3BPFA 1U9WA 3GCBA 3HD3A 4BPVA 1NB3A 3LFYA 4CZWA 1PCIA 5K16A 1PE6A 1AIMA 4WA6A 4YV8A 2OULA 4X6HA 1S4VA 1CQDA 1U9XA 1A6RA 3S3QA 2CB5A 3I06A 3K24A 4P6GA 1CJLA 1PIPA 3F5VA 3ZUAA 4BS5A 2DZZA 4FK5A 2F1GA 4YYUA 1NL6A 4MZSA 4DMXA 4PI3A 3HWNA 3KWZA 4AXLA 2G7YA 2VHSA 1CPJA 5CHTA 1VSNA 4OELA 5CHVA 1ZIVA 4I04A 1CB5A 1AU0A 2PREA 4MZOA 3OVXA 1ICFA 3QSDA 1F2BA 3BOWA 5CVOB 4PADA 1EWOA 1CTEA 1ME4A 2FQ9A 1QOLA 4G54A 4Q8GA 3OF8A 1AU4A 2NQDB 3F75A 4RY2A 5CVMA 1PADA 2VHFA 1BQIA 4OEMA 1MHWA 1MIRA 4YYQA 3KFQA 2IPPB 2XU5A 3IHPA 5CVNB 1KFXL 2JQFR 2YJ9A 3BCNA 1CV8A 2PBHA 4FJCA 2H7JA 3PNRA 3MTNA 3S3RA 3PBHA 1X9YA 5JH3A 3OF9A 5FPWA 5J94A 4YYRA 1NPZA 2DC9A 2R9OA 1PBHA 1FH0A 1ZCMA 3I3TA 1NLJA 2Y6EA 3RVVA 2XU1A 2AVWA 1KHQA 2B1NA 1U9VA 2PNSA 1YK8A 3H6SA 3N4CA 1MEGA 2BDZA 2HH5A 2XU4A 1QMYA 3MHHA 3O0UA 1DF0A 3MORA 3HHAA 1ATKA 3IMAA 2R9FA 4YYWA 2G6DA 3HHIA 1EWMA 3P5VA 4BSQA 1MS6A 3V6CA 3KKUA 1AYUA 1BGOA 3KSEA 4K7CA 3PW3A 1HUCB 1NQCA 3DF0A 2DC8A 2FYEA 1SNKA 1Y08A 2DC7A 1QXPA 3B79A 2C0YA 2OP3A 1U9QX 3RVWA 4KLBA 1KXRA 2P86A 5JA7A 1O0EA 2XU3A 3N3GA 4YVAA 2Y5BA 5EF4A 9PAPA 3NHEA 2O6XA 2R9NA 3RVXA 4N79A 4X6IA 1MDWA 1AU3A 2B1MA 2ATOA 3OVZA 1Y4HA 3MHSA 4N4ZA 1GECE 1SP4B 4QBBA 3QJ3A 2PADA 2AUXA 2AYNA 3H7DA 2YJ8A 4I05A 1PPDA 3BWKA 2NQGA 1EF7A 2IBIA 2BDLA 1PPNA 2NQAA 3O1GA 4YYSA 2ARYA 4XUIA 2YJCA 2HXZA 2G8EA 3AI8A 4P6EA 4W5CA 3CH2X 1EWLA 3H8CA 1KHPA 2AYOA 3P5WA 2AU1A 3C9EA 1DEUA 2P7UA 1PPPA 1YALA 4PP1A 2DCDA 1AU2A 2WBFX 3P5UA 1GCBA 1AYVA 2E02A 2GFOA 2JQGR 3ERVA 2DC6A 4CDFB 4QRGA 2YJ2A 7PCKA 2YJBA 4X6JA 6PADA 3N3KA 4QRVA 2FT2A 3E1ZB 2OZ2A 4AXMA 2ACTA 4BQVA 3D6SA 1BY8A 3QT4A 2DCAA 2R6NA 1TU6A 2FUDA 3H8BA 3LXSA 1VJVA 3IOQA 1PXVA 3CH3X 3IV2A 4CDCB 1PPOA 3KWBX 2FRAA 1ITOA 1CVZA 2HHNA 1THEA 3WXGA 5F02A 4DMYA 2CIOA 2E03A 2P0RA 4CDDB 3KW9A 2F7DA 2R9MA 3CBKA 3USVA 3H89A 2AUZA 1NB5A
chains in the Genus database with same CATH superfamily
3K8UA 1ME3A 4MSXA 2DJGB 2NQIA 3E9SA 1YK7A 5EGWA 5EZSA 3IEJA 3C0RA 1XKGA 4ZUXU 3U8EA 4Q8HA 4YYVA 1Q6KA 5A24A 3KX1A 1AYWA 1STFE 1K3BB 3P5XA 1TLOA 4W4UA 1AECA 4HWYA 2HD5A 3BY4A 3BPMA 2G8JA 1CSBB 5PADA 2FRQA 4W5BA 3K9MA 4MM3B 3PRPA 1CS8A 2AIMA 1YT7A 1F2AA 1F2CA 1GMYA 2DZYA 3WXFA 1F29A 2DCCA 3WXEA 5JZEA 2DJFB 1TL9A 3V6EA 3TNXA 3OISA 4QH6A 8PCHA 3BC3A 4FIPA 1KFUL 4XR7A 2FTDA 1MEMA 4D8BA 1U5IA 3B21A 1GLOA 1JQPA 4PP2E 2E00A 4I07A 1BP4A 4CDEB 4BOUA 1QDQA 1YVBA 3IUTA 1EWPA 3PDFA 2R9CA 2AGAA 4QRXA 1PVJA 3M99A 3CBJA 4BS6A 2JRIA 1M6DA 2E01A 2DCBA 2GHUA 4N8WA 2FO5A 4XZXA 4OVZA 1POPA 1IWDA 2AS8A 3BPFA 1U9WA 3PHUA 3GCBA 3HD3A 3ZNHA 4BPVA 1NB3A 3LFYA 4CZWA 1PCIA 5K16A 1UKFA 4GUAA 1PE6A 1AIMA 4WA6A 4YV8A 2OULA 4X6HA 1S4VA 2BTWB 1CQDA 1U9XA 1A6RA 3S3QA 4PT5A 2CB5A 3I06A 3K24A 4P6GA 3RNVA 1CJLA 1PIPA 3F5VA 3ZUAA 4BS5A 2DZZA 3IFUA 4FK5A 2F1GA 4RKXA 4YYUA 1NL6A 4MZSA 4DMXA 4PI3A 3HWNA 3KWZA 4AXLA 2UZJA 2G7YA 2VHSA 1CPJA 5CHTA 4IUMA 1VSNA 4OELA 5CHVA 4BOQA 1ZIVA 4I04A 1CB5A 1AU0A 2PREA 3MJ5A 4MZOA 5EZQA 3MP2A 3OVXA 1ICFA 3QSDA 1F2BA 3BOWA 5CVOB 4PADA 3W31A 1EWOA 1CTEA 1ME4A 2FQ9A 1QOLA 4G54A 4Q8GA 3OF8A 1AU4A 2NQDB 3F75A 4RY2A 5CVMA 1PADA 2VHFA 1BQIA 4OEMA 1MHWA 1MIRA 4YYQA 3KFQA 2IPPB 2XU5A 3IHPA 4D8IA 5CVNB 4IP3A 3PSEA 1KFXL 2JQFR 2YJ9A 3BCNA 1CV8A 2PBHA 4FJCA 3O65A 2H7JA 3PNRA 3MTNA 3S3RA 3PBHA 1X9YA 5JH3A 3OF9A 3PHXA 5FPWA 5J94A 4YYRA 1NPZA 2DC9A 2R9OA 4A5UA 1PBHA 1FH0A 1ZCMA 3I3TA 1NLJA 2Y6EA 3RVVA 2XU1A 2AVWA 1KHQA 4R3DA 2B1NA 1U9VA 2PNSA 1YK8A 3H6SA 3N4CA 1MEGA 2BDZA 2HH5A 5KO3A 2BTWA 2XU4A 5E6JA 3OQCA 1QMYA 3MHHA 3O0UA 3PT2A 1DF0A 3MORA 3HHAA 1ATKA 3IMAA 2R9FA 3TRKA 4YYWA 1YZBA 2G6DA 3HHIA 1EWMA 3PHWA 3P5VA 4REZA 4BSQA 1MS6A 3V6CA 3KKUA 1AYUA 1BGOA 3KSEA 2Z84A 4K7CA 3PW3A 4RNAA 1HUCB 1NQCA 3BB7A 4MI7A 4WURA 3DF0A 2DC8A 2FYEA 1SNKA 1Y08A 2DC7A 4P16A 3TMPA 1QXPA 3B79A 2C0YA 4D8EA 2OP3A 1U9QX 4RF0A 3RVWA 4KLBA 1KXRA 2P86A 5JA7A 1O0EA 2XU3A 3N3GA 4YVAA 2Y5BA 5EF4A 9PAPA 3NHEA 2O6XA 2R9NA 3RVXA 4N79A 4X6IA 1MDWA 1AU3A 2B1MA 2ATOA 3OVZA 1Y4HA 3MHSA 4N4ZA 1GECE 1SP4B 4QBBA 3QJ3A 2PADA 3BBAA 2JTCA 2FE8A 2AUXA 2AYNA 3H7DA 2YJ8A 4I05A 1PPDA 3BWKA 2NQGA 1EF7A 2IBIA 2BDLA 1PPNA 2NQAA 3O1GA 4YYSA 2ARYA 4XUIA 2YJCA 2HXZA 2G8EA 3AI8A 4P6EA 4M0WA 4W5CA 3CH2X 1EWLA 3H8CA 1KHPA 2AYOA 4HXDB 3P5WA 2AU1A 3C9EA 3W30A 1DEUA 2P7UA 1PPPA 1YALA 4PP1A 2DCDA 1AU2A 4BOPA 2WBFX 3P5UA 1GCBA 1AYVA 4ZTBA 2E02A 2GFOA 2JQGR 3ERVA 2BU3A 2DC6A 4BOSA 3MTVA 4CDFB 2DOSA 4QRGA 2YJ2A 7PCKA 2YJBA 4X6JA 6PADA 3N3KA 4QRVA 2HWKA 4BOZA 2FT2A 3E1ZB 2J7QA 2OZ2A 4AXMA 2ACTA 4BQVA 3D6SA 4RF1A 1BY8A 1DKIA 3QT4A 2DCAA 2R6NA 1TU6A 2FUDA 3H8BA 3LXSA 1VJVA 3IOQA 1PXVA 3CH3X 3IV2A 4CDCB 1PPOA 3KWBX 2FRAA 1ITOA 1CVZA 2HHNA 1THEA 3WXGA 5F02A 4OW0A 4DMYA 2CIOA 2E03A 3PRMA 4OVZB 2P0RA 4CDDB 3KW9A 2F7DA 2R9MA 2J7QC 3CBKA 3USVA 3H89A 2AUZA 1NB5A
chains in the Genus database with same CATH topology
3K8UA 1ME3A 4MSXA 2BSZA 2DJGB 2NQIA 1YK7A 5EGWA 3IEJA 1XKGA 4ZUXU 3U8EA 4Q8HA 4YYVA 1Q6KA 5A24A 3KX1A 1AYWA 1STFE 1K3BB 3P5XA 1TLOA 4W4UA 1AECA 4HWYA 2HD5A 3BPMA 2G8JA 1CSBB 5PADA 2FRQA 2VFBA 4W5BA 3K9MA 1CS8A 2AIMA 1YT7A 1F2AA 1F2CA 1GMYA 2DZYA 3WXFA 1F29A 2DCCA 3WXEA 2DJFB 1TL9A 3V6EA 3TNXA 4B55A 3OISA 4QH6A 8PCHA 3BC3A 4FIPA 1KFUL 4XR7A 2FTDA 1MEMA 1U5IA 1GLOA 1JQPA 4PP2E 2E00A 4I07A 1BP4A 4CDEB 1QDQA 1YVBA 3IUTA 1EWPA 3PDFA 2R9CA 4QRXA 3M99A 3CBJA 4BS6A 1M6DA 2E01A 2DCBA 2GHUA 4N8WA 2FO5A 1POPA 1IWDA 2AS8A 3BPFA 1U9WA 3GCBA 3HD3A 4BPVA 1NB3A 3LFYA 4CZWA 1PCIA 5K16A 1PE6A 1AIMA 4WA6A 4YV8A 2OULA 4X6HA 1S4VA 1CQDA 1U9XA 1A6RA 3S3QA 2CB5A 3I06A 3K24A 4P6GA 1CJLA 1PIPA 3F5VA 3ZUAA 4BS5A 2DZZA 4FK5A 2F1GA 4YYUA 1NL6A 4MZSA 4DMXA 4PI3A 3HWNA 3KWZA 4AXLA 2G7YA 4GUZA 2VHSA 1CPJA 4NV7A 5CHTA 1VSNA 4OELA 5CHVA 1ZIVA 4I04A 1CB5A 1AU0A 2PREA 4MZOA 3D9WA 3OVXA 1ICFA 3QSDA 1F2BA 3BOWA 5CVOB 4PADA 1EWOA 1CTEA 1ME4A 2FQ9A 1QOLA 4G54A 4Q8GA 3OF8A 1AU4A 2NQDB 3F75A 4RY2A 5CVMA 1PADA 2VHFA 1BQIA 4OEMA 1MHWA 1MIRA 4YYQA 3KFQA 2IPPB 2XU5A 1E2TA 3IHPA 5CVNB 4BGFA 1KFXL 2JQFR 2YJ9A 4C5PA 3BCNA 1CV8A 2PBHA 4FJCA 2H7JA 3PNRA 3MTNA 1W5RA 3S3RA 3PBHA 1X9YA 5JH3A 3OF9A 5FPWA 2VFCA 5J94A 4YYRA 1NPZA 2DC9A 2R9OA 1PBHA 1FH0A 1ZCMA 3I3TA 1NLJA 2Y6EA 3RVVA 2XU1A 2AVWA 1KHQA 2B1NA 1U9VA 2PNSA 1YK8A 3H6SA 3N4CA 1MEGA 2BDZA 2HH5A 2XU4A 1QMYA 3MHHA 3O0UA 1DF0A 3MORA 3HHAA 1ATKA 3IMAA 2R9FA 4YYWA 2G6DA 3HHIA 1EWMA 3P5VA 4BSQA 1MS6A 3V6CA 3KKUA 1AYUA 1BGOA 3KSEA 4K7CA 3PW3A 1HUCB 1NQCA 3DF0A 2DC8A 2FYEA 1SNKA 1Y08A 2DC7A 1QXPA 3B79A 2C0YA 2OP3A 1U9QX 3RVWA 4KLBA 1KXRA 2P86A 5JA7A 1O0EA 2XU3A 3N3GA 4YVAA 2Y5BA 5EF4A 9PAPA 3NHEA 2O6XA 2R9NA 3RVXA 4N79A 3LTWA 4X6IA 1MDWA 1AU3A 2B1MA 2ATOA 3OVZA 1Y4HA 3MHSA 4N4ZA 1GECE 1SP4B 4QBBA 3QJ3A 2PADA 2AUXA 2AYNA 3H7DA 2YJ8A 4I05A 1PPDA 3BWKA 2NQGA 1EF7A 2IBIA 1W6FA 2BDLA 1PPNA 2NQAA 3O1GA 4YYSA 2ARYA 4XUIA 2YJCA 2HXZA 2G8EA 3AI8A 4P6EA 4W5CA 3CH2X 1EWLA 3H8CA 1KHPA 2AYOA 3P5WA 2AU1A 3C9EA 1DEUA 2P7UA 1PPPA 1YALA 4PP1A 2DCDA 1AU2A 2WBFX 3P5UA 1GCBA 1AYVA 2E02A 2GFOA 2JQGR 3ERVA 2DC6A 4CDFB 4NV8A 4QRGA 1W4TA 2YJ2A 7PCKA 2YJBA 4X6JA 6PADA 3N3KA 4QRVA 2FT2A 3E1ZB 2OZ2A 4AXMA 2ACTA 4BQVA 3D6SA 1BY8A 3QT4A 2DCAA 2R6NA 1TU6A 2FUDA 3H8BA 3LXSA 1VJVA 3IOQA 1PXVA 3CH3X 3IV2A 4CDCB 1PPOA 3KWBX 2FRAA 1ITOA 1CVZA 2HHNA 1THEA 3WXGA 5F02A 4DMYA 2CIOA 2E03A 2P0RA 4CDDB 3KW9A 2F7DA 2R9MA 3CBKA 3USVA 1GX3A 3H89A 2AUZA 1NB5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3K8U A;  1ME3 A;  4MSX A;  2DJG B;  2NQI A;  1YK7 A;  5EGW A;  3IEJ A;  1XKG A;  4ZUX U;  3U8E A;  4Q8H A;  4YYV A;  1Q6K A;  5A24 A;  3KX1 A;  1AYW A;  1STF E;  1K3B B;  3P5X A;  1TLO A;  4W4U A;  1AEC A;  4HWY A;  2HD5 A;  3BPM A;  2G8J A;  1CSB B;  5PAD A;  2FRQ A;  4W5B A;  3K9M A;  1CS8 A;  2AIM A;  1YT7 A;  1F2A A;  1F2C A;  1GMY A;  2DZY A;  3WXF A;  1F29 A;  2DCC A;  3WXE A;  2DJF B;  1TL9 A;  3V6E A;  3TNX A;  3OIS A;  4QH6 A;  8PCH A;  3BC3 A;  4FIP A;  1KFU L;  4XR7 A;  2FTD A;  1MEM A;  1U5I A;  1GLO A;  1JQP A;  4PP2 E;  2E00 A;  4I07 A;  1BP4 A;  4CDE B;  1QDQ A;  1YVB A;  3IUT A;  1EWP A;  3PDF A;  2R9C A;  4QRX A;  3M99 A;  3CBJ A;  4BS6 A;  1M6D A;  2E01 A;  2DCB A;  2GHU A;  4N8W A;  2FO5 A;  1POP A;  1IWD A;  2AS8 A;  3BPF A;  1U9W A;  3GCB A;  3HD3 A;  4BPV A;  1NB3 A;  3LFY A;  4CZW A;  1PCI A;  5K16 A;  1PE6 A;  1AIM A;  4WA6 A;  4YV8 A;  2OUL A;  4X6H A;  1S4V A;  1CQD A;  1U9X A;  1A6R A;  3S3Q A;  2CB5 A;  3I06 A;  3K24 A;  4P6G A;  1CJL A;  1PIP A;  3F5V A;  3ZUA A;  4BS5 A;  2DZZ A;  4FK5 A;  2F1G A;  4YYU A;  1NL6 A;  4MZS A;  4DMX A;  4PI3 A;  3HWN A;  3KWZ A;  4AXL A;  2G7Y A;  2VHS A;  1CPJ A;  5CHT A;  1VSN A;  4OEL A;  5CHV A;  1ZIV A;  4I04 A;  1CB5 A;  1AU0 A;  2PRE A;  4MZO A;  3OVX A;  1ICF A;  3QSD A;  1F2B A;  3BOW A;  5CVO B;  4PAD A;  1EWO A;  1CTE A;  1ME4 A;  2FQ9 A;  1QOL A;  4G54 A;  4Q8G A;  3OF8 A;  1AU4 A;  2NQD B;  3F75 A;  4RY2 A;  5CVM A;  1PAD A;  2VHF A;  1BQI A;  4OEM A;  1MHW A;  1MIR A;  4YYQ A;  3KFQ A;  2IPP B;  2XU5 A;  3IHP A;  5CVN B;  1KFX L;  2JQF R;  2YJ9 A;  3BCN A;  1CV8 A;  2PBH A;  4FJC A;  2H7J A;  3PNR A;  3MTN A;  3S3R A;  3PBH A;  1X9Y A;  5JH3 A;  3OF9 A;  5FPW A;  5J94 A;  4YYR A;  1NPZ A;  2DC9 A;  2R9O A;  1PBH A;  1FH0 A;  1ZCM A;  3I3T A;  1NLJ A;  2Y6E A;  3RVV A;  2XU1 A;  2AVW A;  1KHQ A;  2B1N A;  1U9V A;  2PNS A;  1YK8 A;  3H6S A;  3N4C A;  1MEG A;  2BDZ A;  2HH5 A;  2XU4 A;  1QMY A;  3MHH A;  3O0U A;  1DF0 A;  3MOR A;  3HHA A;  1ATK A;  3IMA A;  2R9F A;  4YYW A;  2G6D A;  3HHI A;  1EWM A;  3P5V A;  4BSQ A;  1MS6 A;  3V6C A;  3KKU A;  1AYU A;  1BGO A;  3KSE A;  4K7C A;  3PW3 A;  1HUC B;  1NQC A;  3DF0 A;  2DC8 A;  2FYE A;  1SNK A;  1Y08 A;  2DC7 A;  1QXP A;  3B79 A;  2C0Y A;  2OP3 A;  1U9Q X;  3RVW A;  4KLB A;  1KXR A;  2P86 A;  5JA7 A;  1O0E A;  2XU3 A;  3N3G A;  4YVA A;  2Y5B A;  5EF4 A;  9PAP A;  3NHE A;  2O6X A;  2R9N A;  3RVX A;  4N79 A;  4X6I A;  1MDW A;  1AU3 A;  2B1M A;  2ATO A;  3OVZ A;  1Y4H A;  3MHS A;  4N4Z A;  1GEC E;  1SP4 B;  4QBB A;  3QJ3 A;  2PAD A;  2AUX A;  2AYN A;  3H7D A;  2YJ8 A;  4I05 A;  1PPD A;  3BWK A;  2NQG A;  1EF7 A;  2IBI A;  2BDL A;  1PPN A;  2NQA A;  3O1G A;  4YYS A;  2ARY A;  4XUI A;  2YJC A;  2HXZ A;  2G8E A;  3AI8 A;  4P6E A;  4W5C A;  3CH2 X;  1EWL A;  3H8C A;  1KHP A;  2AYO A;  3P5W A;  2AU1 A;  3C9E A;  1DEU A;  2P7U A;  1PPP A;  1YAL A;  4PP1 A;  2DCD A;  1AU2 A;  2WBF X;  3P5U A;  1GCB A;  1AYV A;  2E02 A;  2GFO A;  2JQG R;  3ERV A;  2DC6 A;  4CDF B;  4QRG A;  2YJ2 A;  7PCK A;  2YJB A;  4X6J A;  6PAD A;  3N3K A;  4QRV A;  2FT2 A;  3E1Z B;  2OZ2 A;  4AXM A;  2ACT A;  4BQV A;  3D6S A;  1BY8 A;  3QT4 A;  2DCA A;  2R6N A;  1TU6 A;  2FUD A;  3H8B A;  3LXS A;  1VJV A;  3IOQ A;  1PXV A;  3CH3 X;  3IV2 A;  4CDC B;  1PPO A;  3KWB X;  2FRA A;  1ITO A;  1CVZ A;  2HHN A;  1THE A;  3WXG A;  5F02 A;  4DMY A;  2CIO A;  2E03 A;  2P0R A;  4CDD B;  3KW9 A;  2F7D A;  2R9M A;  3CBK A;  3USV A;  3H89 A;  2AUZ A;  1NB5 A; 
#chains in the Genus database with same CATH topology
 3K8U A;  1ME3 A;  4MSX A;  2DJG B;  2NQI A;  3E9S A;  1YK7 A;  5EGW A;  5EZS A;  3IEJ A;  3C0R A;  1XKG A;  4ZUX U;  3U8E A;  4Q8H A;  4YYV A;  1Q6K A;  5A24 A;  3KX1 A;  1AYW A;  1STF E;  1K3B B;  3P5X A;  1TLO A;  4W4U A;  1AEC A;  4HWY A;  2HD5 A;  3BY4 A;  3BPM A;  2G8J A;  1CSB B;  5PAD A;  2FRQ A;  4W5B A;  3K9M A;  4MM3 B;  3PRP A;  1CS8 A;  2AIM A;  1YT7 A;  1F2A A;  1F2C A;  1GMY A;  2DZY A;  3WXF A;  1F29 A;  2DCC A;  3WXE A;  5JZE A;  2DJF B;  1TL9 A;  3V6E A;  3TNX A;  3OIS A;  4QH6 A;  8PCH A;  3BC3 A;  4FIP A;  1KFU L;  4XR7 A;  2FTD A;  1MEM A;  4D8B A;  1U5I A;  3B21 A;  1GLO A;  1JQP A;  4PP2 E;  2E00 A;  4I07 A;  1BP4 A;  4CDE B;  4BOU A;  1QDQ A;  1YVB A;  3IUT A;  1EWP A;  3PDF A;  2R9C A;  2AGA A;  4QRX A;  1PVJ A;  3M99 A;  3CBJ A;  4BS6 A;  2JRI A;  1M6D A;  2E01 A;  2DCB A;  2GHU A;  4N8W A;  2FO5 A;  4XZX A;  4OVZ A;  1POP A;  1IWD A;  2AS8 A;  3BPF A;  1U9W A;  3PHU A;  3GCB A;  3HD3 A;  3ZNH A;  4BPV A;  1NB3 A;  3LFY A;  4CZW A;  1PCI A;  5K16 A;  1UKF A;  4GUA A;  1PE6 A;  1AIM A;  4WA6 A;  4YV8 A;  2OUL A;  4X6H A;  1S4V A;  2BTW B;  1CQD A;  1U9X A;  1A6R A;  3S3Q A;  4PT5 A;  2CB5 A;  3I06 A;  3K24 A;  4P6G A;  3RNV A;  1CJL A;  1PIP A;  3F5V A;  3ZUA A;  4BS5 A;  2DZZ A;  3IFU A;  4FK5 A;  2F1G A;  4RKX A;  4YYU A;  1NL6 A;  4MZS A;  4DMX A;  4PI3 A;  3HWN A;  3KWZ A;  4AXL A;  2UZJ A;  2G7Y A;  2VHS A;  1CPJ A;  5CHT A;  4IUM A;  1VSN A;  4OEL A;  5CHV A;  4BOQ A;  1ZIV A;  4I04 A;  1CB5 A;  1AU0 A;  2PRE A;  3MJ5 A;  4MZO A;  5EZQ A;  3MP2 A;  3OVX A;  1ICF A;  3QSD A;  1F2B A;  3BOW A;  5CVO B;  4PAD A;  3W31 A;  1EWO A;  1CTE A;  1ME4 A;  2FQ9 A;  1QOL A;  4G54 A;  4Q8G A;  3OF8 A;  1AU4 A;  2NQD B;  3F75 A;  4RY2 A;  5CVM A;  1PAD A;  2VHF A;  1BQI A;  4OEM A;  1MHW A;  1MIR A;  4YYQ A;  3KFQ A;  2IPP B;  2XU5 A;  3IHP A;  4D8I A;  5CVN B;  4IP3 A;  3PSE A;  1KFX L;  2JQF R;  2YJ9 A;  3BCN A;  1CV8 A;  2PBH A;  4FJC A;  3O65 A;  2H7J A;  3PNR A;  3MTN A;  3S3R A;  3PBH A;  1X9Y A;  5JH3 A;  3OF9 A;  3PHX A;  5FPW A;  5J94 A;  4YYR A;  1NPZ A;  2DC9 A;  2R9O A;  4A5U A;  1PBH A;  1FH0 A;  1ZCM A;  3I3T A;  1NLJ A;  2Y6E A;  3RVV A;  2XU1 A;  2AVW A;  1KHQ A;  4R3D A;  2B1N A;  1U9V A;  2PNS A;  1YK8 A;  3H6S A;  3N4C A;  1MEG A;  2BDZ A;  2HH5 A;  5KO3 A;  2BTW A;  2XU4 A;  5E6J A;  3OQC A;  1QMY A;  3MHH A;  3O0U A;  3PT2 A;  1DF0 A;  3MOR A;  3HHA A;  1ATK A;  3IMA A;  2R9F A;  3TRK A;  4YYW A;  1YZB A;  2G6D A;  3HHI A;  1EWM A;  3PHW A;  3P5V A;  4REZ A;  4BSQ A;  1MS6 A;  3V6C A;  3KKU A;  1AYU A;  1BGO A;  3KSE A;  2Z84 A;  4K7C A;  3PW3 A;  4RNA A;  1HUC B;  1NQC A;  3BB7 A;  4MI7 A;  4WUR A;  3DF0 A;  2DC8 A;  2FYE A;  1SNK A;  1Y08 A;  2DC7 A;  4P16 A;  3TMP A;  1QXP A;  3B79 A;  2C0Y A;  4D8E A;  2OP3 A;  1U9Q X;  4RF0 A;  3RVW A;  4KLB A;  1KXR A;  2P86 A;  5JA7 A;  1O0E A;  2XU3 A;  3N3G A;  4YVA A;  2Y5B A;  5EF4 A;  9PAP A;  3NHE A;  2O6X A;  2R9N A;  3RVX A;  4N79 A;  4X6I A;  1MDW A;  1AU3 A;  2B1M A;  2ATO A;  3OVZ A;  1Y4H A;  3MHS A;  4N4Z A;  1GEC E;  1SP4 B;  4QBB A;  3QJ3 A;  2PAD A;  3BBA A;  2JTC A;  2FE8 A;  2AUX A;  2AYN A;  3H7D A;  2YJ8 A;  4I05 A;  1PPD A;  3BWK A;  2NQG A;  1EF7 A;  2IBI A;  2BDL A;  1PPN A;  2NQA A;  3O1G A;  4YYS A;  2ARY A;  4XUI A;  2YJC A;  2HXZ A;  2G8E A;  3AI8 A;  4P6E A;  4M0W A;  4W5C A;  3CH2 X;  1EWL A;  3H8C A;  1KHP A;  2AYO A;  4HXD B;  3P5W A;  2AU1 A;  3C9E A;  3W30 A;  1DEU A;  2P7U A;  1PPP A;  1YAL A;  4PP1 A;  2DCD A;  1AU2 A;  4BOP A;  2WBF X;  3P5U A;  1GCB A;  1AYV A;  4ZTB A;  2E02 A;  2GFO A;  2JQG R;  3ERV A;  2BU3 A;  2DC6 A;  4BOS A;  3MTV A;  4CDF B;  2DOS A;  4QRG A;  2YJ2 A;  7PCK A;  2YJB A;  4X6J A;  6PAD A;  3N3K A;  4QRV A;  2HWK A;  4BOZ A;  2FT2 A;  3E1Z B;  2J7Q A;  2OZ2 A;  4AXM A;  2ACT A;  4BQV A;  3D6S A;  4RF1 A;  1BY8 A;  1DKI A;  3QT4 A;  2DCA A;  2R6N A;  1TU6 A;  2FUD A;  3H8B A;  3LXS A;  1VJV A;  3IOQ A;  1PXV A;  3CH3 X;  3IV2 A;  4CDC B;  1PPO A;  3KWB X;  2FRA A;  1ITO A;  1CVZ A;  2HHN A;  1THE A;  3WXG A;  5F02 A;  4OW0 A;  4DMY A;  2CIO A;  2E03 A;  3PRM A;  4OVZ B;  2P0R A;  4CDD B;  3KW9 A;  2F7D A;  2R9M A;  2J7Q C;  3CBK A;  3USV A;  3H89 A;  2AUZ A;  1NB5 A; 
#chains in the Genus database with same CATH homology
 3K8U A;  1ME3 A;  4MSX A;  2BSZ A;  2DJG B;  2NQI A;  1YK7 A;  5EGW A;  3IEJ A;  1XKG A;  4ZUX U;  3U8E A;  4Q8H A;  4YYV A;  1Q6K A;  5A24 A;  3KX1 A;  1AYW A;  1STF E;  1K3B B;  3P5X A;  1TLO A;  4W4U A;  1AEC A;  4HWY A;  2HD5 A;  3BPM A;  2G8J A;  1CSB B;  5PAD A;  2FRQ A;  2VFB A;  4W5B A;  3K9M A;  1CS8 A;  2AIM A;  1YT7 A;  1F2A A;  1F2C A;  1GMY A;  2DZY A;  3WXF A;  1F29 A;  2DCC A;  3WXE A;  2DJF B;  1TL9 A;  3V6E A;  3TNX A;  4B55 A;  3OIS A;  4QH6 A;  8PCH A;  3BC3 A;  4FIP A;  1KFU L;  4XR7 A;  2FTD A;  1MEM A;  1U5I A;  1GLO A;  1JQP A;  4PP2 E;  2E00 A;  4I07 A;  1BP4 A;  4CDE B;  1QDQ A;  1YVB A;  3IUT A;  1EWP A;  3PDF A;  2R9C A;  4QRX A;  3M99 A;  3CBJ A;  4BS6 A;  1M6D A;  2E01 A;  2DCB A;  2GHU A;  4N8W A;  2FO5 A;  1POP A;  1IWD A;  2AS8 A;  3BPF A;  1U9W A;  3GCB A;  3HD3 A;  4BPV A;  1NB3 A;  3LFY A;  4CZW A;  1PCI A;  5K16 A;  1PE6 A;  1AIM A;  4WA6 A;  4YV8 A;  2OUL A;  4X6H A;  1S4V A;  1CQD A;  1U9X A;  1A6R A;  3S3Q A;  2CB5 A;  3I06 A;  3K24 A;  4P6G A;  1CJL A;  1PIP A;  3F5V A;  3ZUA A;  4BS5 A;  2DZZ A;  4FK5 A;  2F1G A;  4YYU A;  1NL6 A;  4MZS A;  4DMX A;  4PI3 A;  3HWN A;  3KWZ A;  4AXL A;  2G7Y A;  4GUZ A;  2VHS A;  1CPJ A;  4NV7 A;  5CHT A;  1VSN A;  4OEL A;  5CHV A;  1ZIV A;  4I04 A;  1CB5 A;  1AU0 A;  2PRE A;  4MZO A;  3D9W A;  3OVX A;  1ICF A;  3QSD A;  1F2B A;  3BOW A;  5CVO B;  4PAD A;  1EWO A;  1CTE A;  1ME4 A;  2FQ9 A;  1QOL A;  4G54 A;  4Q8G A;  3OF8 A;  1AU4 A;  2NQD B;  3F75 A;  4RY2 A;  5CVM A;  1PAD A;  2VHF A;  1BQI A;  4OEM A;  1MHW A;  1MIR A;  4YYQ A;  3KFQ A;  2IPP B;  2XU5 A;  1E2T A;  3IHP A;  5CVN B;  4BGF A;  1KFX L;  2JQF R;  2YJ9 A;  4C5P A;  3BCN A;  1CV8 A;  2PBH A;  4FJC A;  2H7J A;  3PNR A;  3MTN A;  1W5R A;  3S3R A;  3PBH A;  1X9Y A;  5JH3 A;  3OF9 A;  5FPW A;  2VFC A;  5J94 A;  4YYR A;  1NPZ A;  2DC9 A;  2R9O A;  1PBH A;  1FH0 A;  1ZCM A;  3I3T A;  1NLJ A;  2Y6E A;  3RVV A;  2XU1 A;  2AVW A;  1KHQ A;  2B1N A;  1U9V A;  2PNS A;  1YK8 A;  3H6S A;  3N4C A;  1MEG A;  2BDZ A;  2HH5 A;  2XU4 A;  1QMY A;  3MHH A;  3O0U A;  1DF0 A;  3MOR A;  3HHA A;  1ATK A;  3IMA A;  2R9F A;  4YYW A;  2G6D A;  3HHI A;  1EWM A;  3P5V A;  4BSQ A;  1MS6 A;  3V6C A;  3KKU A;  1AYU A;  1BGO A;  3KSE A;  4K7C A;  3PW3 A;  1HUC B;  1NQC A;  3DF0 A;  2DC8 A;  2FYE A;  1SNK A;  1Y08 A;  2DC7 A;  1QXP A;  3B79 A;  2C0Y A;  2OP3 A;  1U9Q X;  3RVW A;  4KLB A;  1KXR A;  2P86 A;  5JA7 A;  1O0E A;  2XU3 A;  3N3G A;  4YVA A;  2Y5B A;  5EF4 A;  9PAP A;  3NHE A;  2O6X A;  2R9N A;  3RVX A;  4N79 A;  3LTW A;  4X6I A;  1MDW A;  1AU3 A;  2B1M A;  2ATO A;  3OVZ A;  1Y4H A;  3MHS A;  4N4Z A;  1GEC E;  1SP4 B;  4QBB A;  3QJ3 A;  2PAD A;  2AUX A;  2AYN A;  3H7D A;  2YJ8 A;  4I05 A;  1PPD A;  3BWK A;  2NQG A;  1EF7 A;  2IBI A;  1W6F A;  2BDL A;  1PPN A;  2NQA A;  3O1G A;  4YYS A;  2ARY A;  4XUI A;  2YJC A;  2HXZ A;  2G8E A;  3AI8 A;  4P6E A;  4W5C A;  3CH2 X;  1EWL A;  3H8C A;  1KHP A;  2AYO A;  3P5W A;  2AU1 A;  3C9E A;  1DEU A;  2P7U A;  1PPP A;  1YAL A;  4PP1 A;  2DCD A;  1AU2 A;  2WBF X;  3P5U A;  1GCB A;  1AYV A;  2E02 A;  2GFO A;  2JQG R;  3ERV A;  2DC6 A;  4CDF B;  4NV8 A;  4QRG A;  1W4T A;  2YJ2 A;  7PCK A;  2YJB A;  4X6J A;  6PAD A;  3N3K A;  4QRV A;  2FT2 A;  3E1Z B;  2OZ2 A;  4AXM A;  2ACT A;  4BQV A;  3D6S A;  1BY8 A;  3QT4 A;  2DCA A;  2R6N A;  1TU6 A;  2FUD A;  3H8B A;  3LXS A;  1VJV A;  3IOQ A;  1PXV A;  3CH3 X;  3IV2 A;  4CDC B;  1PPO A;  3KWB X;  2FRA A;  1ITO A;  1CVZ A;  2HHN A;  1THE A;  3WXG A;  5F02 A;  4DMY A;  2CIO A;  2E03 A;  2P0R A;  4CDD B;  3KW9 A;  2F7D A;  2R9M A;  3CBK A;  3USV A;  1GX3 A;  3H89 A;  2AUZ A;  1NB5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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