2YJ9A

Cathepsin l with a nitrile inhibitor
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
220
structure length
216
Chain Sequence
APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFEDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Halogen Bonding at the Active Sites of Human Cathepsin L and Mek1 Kinase: Efficient Interactions in Different Environments.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords CATHEPSIN L1
total genus 69
structure length 216
sequence length 220
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2011-05-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2yj9A00
4PP2E 1DF0A 1ZIVA 2G8EA 3PNRA 3OF8A 5CVNB 4QRXA 1AECA 2E00A 3AI8A 1S4VA 1O0EA 2H7JA 2P0RA 1AU3A 4FIPA 5J94A 1AYVA 3I06A 2R9MA 1GMYA 3QJ3A 4I04A 3U8EA 3H89A 2YJ9A 1QMYA 2XU4A 1A6RA 3NHEA 4CDCB 5F02A 2B1MA 2NQIA 3ZUAA 1PPPA 2OP3A 3KWBX 2E02A 4I07A 1ICFA 1KFUL 2YJ2A 5CHVA 2PREA 3MTNA 2NQAA 1EWOA 7PCKA 4MZOA 1NB5A 4MSXA 3K9MA 2DZYA 3KWZA 1ATKA 8PCHA 2AS8A 4KLBA 1CVZA 2AYNA 2FQ9A 1YALA 4XR7A 2C0YA 2GHUA 4W4UA 1STFE 1Y4HA 3V6EA 3KW9A 4YV8A 1PADA 3OVZA 4AXLA 1AU4A 3BOWA 2G7YA 2FUDA 3C9EA 2AVWA 4CDFB 2DCBA 2Y6EA 2Y5BA 1CSBB 4ZUXU 5FPWA 2OZ2A 3KSEA 4W5CA 4N79A 2OULA 3TNXA 1KHQA 3IHPA 1TU6A 1VJVA 1TL9A 4Q8GA 2FRAA 2ARYA 3GCBA 2BDLA 1CB5A 1CJLA 2VHSA 4BSQA 4CDEB 2PNSA 2G6DA 3MHSA 3OVXA 2DCCA 3N3KA 1U9WA 1GECE 3LFYA 2JQGR 2DC6A 2B1NA 1X9YA 1VSNA 4I05A 1AYUA 2DC9A 3RVWA 5CVMA 4DMXA 2PADA 1AIMA 3O0UA 4BQVA 2E03A 2XU3A 4XUIA 3K8UA 3CBJA 4X6IA 2DJGB 2ACTA 4DMYA 4QH6A 4PP1A 3S3RA 1DEUA 1NL6A 1BQIA 3P5WA 1BGOA 1F2AA 4YYSA 2AYOA 2AUZA 1F29A 4X6JA 5PADA 2AU1A 3PBHA 1MIRA 1ITOA 4PI3A 3RVVA 4P6GA 1QOLA 4QRGA 4QRVA 4Q8HA 2ATOA 4P6EA 1U9QX 2E01A 3IEJA 3BPFA 1CQDA 3RVXA 3OF9A 3D6SA 3PDFA 4OEMA 4CZWA 1PPNA 2G8JA 1GLOA 5JH3A 3HHIA 1TLOA 2R9NA 4YYUA 1CPJA 3CH3X 1YK7A 5JA7A 4YVAA 3CH2X 1F2CA 2P7UA 3PW3A 1POPA 2FYEA 2HD5A 4FK5A 5A24A 1MHWA 2IBIA 1QXPA 4YYVA 3H8BA 1MS6A 3HHAA 2HH5A 1MDWA 2YJCA 1CV8A 1MEMA 1YT7A 1KHPA 1M6DA 3IMAA 2JQFR 2DC8A 1JQPA 1CS8A 2XU1A 1ZCMA 1SP4B 1KXRA 3F5VA 1PE6A 1YK8A 2HHNA 3B79A 3P5XA 4K7CA 1PBHA 2R9CA 3WXEA 4FJCA 1U5IA 2NQDB 1THEA 2IPPB 1PPOA 3USVA 3KX1A 3KFQA 1EF7A 3F75A 1NQCA 2CIOA 1XKGA 3H8CA 1Y08A 1EWMA 3WXGA 1AYWA 1CTEA 4HWYA 1PXVA 3P5UA 4G54A 4RY2A 1HUCB 2HXZA 3V6CA 2FRQA 4AXMA 4N8WA 3DF0A 3QSDA 2DC7A 2F1GA 1SNKA 3H7DA 3BWKA 1F2BA 4X6HA 4BS6A 1BY8A 2DCAA 3E1ZB 9PAPA 1AU0A 4YYWA 2FO5A 4YYQA 3S3QA 1U9VA 3OISA 1QDQA 2DJFB 4WA6A 1PIPA 1NB3A 2NQGA 1Q6KA 5EGWA 3CBKA 5EF4A 4BS5A 2XU5A 2CB5A 3HD3A 3M99A 1FH0A 3ERVA 2VHFA 3BPMA 3I3TA 4OELA 2DZZA 3IUTA 1PPDA 4YYRA 1ME4A 1NPZA 2FT2A 6PADA 2DCDA 4N4ZA 3IV2A 1YVBA 1ME3A 2F7DA 3MORA 3N4CA 3QT4A 1U9XA 3BC3A 1PCIA 5K16A 2P86A 5CVOB 1EWPA 2R9FA 3N3GA 3K24A 3P5VA 3KKUA 3HWNA 2O6XA 2R9OA 1KFXL 4QBBA 1EWLA 3IOQA 2PBHA 3WXFA 4BPVA 2R6NA 4PADA 2BDZA 2YJBA 4MZSA 1K3BB 2YJ8A 1NLJA 2GFOA 1BP4A 1MEGA 2WBFX 4W5BA 2FTDA 4CDDB 3H6SA 1AU2A 3LXSA 1IWDA 3BCNA 5CHTA 1GCBA 2AUXA 3MHHA 3O1GA 2AIMA
chains in the Genus database with same CATH superfamily
4PP2E 3W30A 1DF0A 1ZIVA 2G8EA 3PNRA 3OF8A 5CVNB 4QRXA 1AECA 2E00A 1PVJA 3AI8A 3BB7A 1S4VA 1O0EA 2H7JA 2P0RA 1AU3A 4FIPA 4HXDB 5J94A 1AYVA 3BY4A 3I06A 2R9MA 1GMYA 3QJ3A 4I04A 3U8EA 3H89A 2YJ9A 1QMYA 2XU4A 1A6RA 3NHEA 4CDCB 5F02A 2B1MA 4IP3A 3PT2A 2JTCA 2NQIA 3ZUAA 1PPPA 2OP3A 5JZEA 3KWBX 2E02A 4I07A 1ICFA 1KFUL 4BOPA 2YJ2A 5CHVA 2PREA 3MTNA 2NQAA 1EWOA 7PCKA 4MZOA 1NB5A 4MSXA 3K9MA 2DZYA 3E9SA 3KWZA 1ATKA 1DKIA 8PCHA 2AS8A 4KLBA 1CVZA 2AYNA 2FQ9A 1YALA 4XR7A 2C0YA 2GHUA 4W4UA 1STFE 1Y4HA 3V6EA 3KW9A 4YV8A 1PADA 3OVZA 4AXLA 3OQCA 1AU4A 4REZA 3BOWA 2G7YA 2FUDA 3C9EA 2AVWA 4CDFB 2DCBA 2Y6EA 4D8IA 2Y5BA 3PRMA 1CSBB 4ZUXU 5FPWA 2OZ2A 3KSEA 4W5CA 4A5UA 3W31A 4N79A 2OULA 3TNXA 1KHQA 3IHPA 1TU6A 1VJVA 1TL9A 4Q8GA 2FRAA 2ARYA 3GCBA 2AGAA 4OVZA 2BDLA 4D8BA 1CB5A 1CJLA 2VHSA 4BSQA 2BTWA 4CDEB 2PNSA 2G6DA 3MHSA 3OVXA 2DCCA 3N3KA 4RNAA 2JRIA 1U9WA 1GECE 3LFYA 3MTVA 1UKFA 3IFUA 4RKXA 2JQGR 2DC6A 2B1NA 1X9YA 1VSNA 4I05A 1AYUA 2DC9A 3RVWA 5CVMA 4DMXA 2PADA 4PT5A 1AIMA 5KO3A 3O0UA 4BQVA 2E03A 2XU3A 4XUIA 3K8UA 4D8EA 3CBJA 4X6IA 2DJGB 2ACTA 4DMYA 4QH6A 4PP1A 3S3RA 1DEUA 1NL6A 3O65A 1BQIA 3P5WA 1BGOA 1F2AA 4YYSA 2AYOA 2AUZA 2FE8A 1F29A 3PHUA 4X6JA 5PADA 2AU1A 3PBHA 3TMPA 1MIRA 4BOZA 1ITOA 4PI3A 3RVVA 4P6GA 1QOLA 4QRGA 4QRVA 3BBAA 4Q8HA 2ATOA 4P6EA 1U9QX 2E01A 3MP2A 3IEJA 3BPFA 2Z84A 1CQDA 3RVXA 3OF9A 3D6SA 3PDFA 3B21A 4OEMA 4CZWA 1PPNA 2G8JA 1GLOA 5JH3A 3HHIA 4GUAA 1TLOA 2R9NA 4YYUA 1CPJA 3CH3X 1YK7A 5JA7A 4YVAA 3CH2X 1F2CA 2P7UA 3PW3A 1POPA 2FYEA 2HD5A 4FK5A 5A24A 4M0WA 1MHWA 2IBIA 4MI7A 1QXPA 4YYVA 3H8BA 1MS6A 3HHAA 4R3DA 4BOQA 2HH5A 1MDWA 3C0RA 2YJCA 1CV8A 1MEMA 1YT7A 1KHPA 1M6DA 4IUMA 1YZBA 3IMAA 2JQFR 2DC8A 1JQPA 1CS8A 2XU1A 1ZCMA 3TRKA 1SP4B 1KXRA 3F5VA 1PE6A 1YK8A 2HHNA 3B79A 3P5XA 5E6JA 4K7CA 1PBHA 2R9CA 3WXEA 4FJCA 1U5IA 2NQDB 1THEA 2HWKA 2IPPB 1PPOA 5EZSA 3USVA 3KX1A 3KFQA 1EF7A 3F75A 1NQCA 2CIOA 1XKGA 3H8CA 1Y08A 4BOSA 1EWMA 3WXGA 1AYWA 1CTEA 2J7QA 3PHXA 4HWYA 1PXVA 3P5UA 4ZTBA 4G54A 4RY2A 1HUCB 2HXZA 3V6CA 2FRQA 4AXMA 2UZJA 4N8WA 3DF0A 3QSDA 2DC7A 2F1GA 1SNKA 4WURA 3H7DA 3BWKA 1F2BA 5EZQA 4X6HA 4BS6A 1BY8A 2DCAA 3E1ZB 9PAPA 1AU0A 4OVZB 4YYWA 2FO5A 4YYQA 3S3QA 1U9VA 3OISA 2BTWB 1QDQA 2DJFB 4WA6A 1PIPA 1NB3A 2NQGA 1Q6KA 5EGWA 3CBKA 4MM3B 5EF4A 4RF1A 4BS5A 2XU5A 2CB5A 3HD3A 3M99A 3PHWA 1FH0A 3ERVA 2VHFA 3BPMA 3I3TA 4P16A 4OELA 2DZZA 2J7QC 3RNVA 4XZXA 3IUTA 1PPDA 4YYRA 1ME4A 1NPZA 2FT2A 6PADA 3PRPA 2DCDA 2DOSA 4N4ZA 3IV2A 1YVBA 1ME3A 2F7DA 3MORA 3N4CA 3QT4A 1U9XA 3BC3A 1PCIA 5K16A 2P86A 3ZNHA 5CVOB 1EWPA 2R9FA 3N3GA 3K24A 4RF0A 3P5VA 3KKUA 2BU3A 3HWNA 2O6XA 2R9OA 1KFXL 4QBBA 1EWLA 3IOQA 3PSEA 2PBHA 4BOUA 3WXFA 4BPVA 2R6NA 4PADA 3MJ5A 2BDZA 2YJBA 4MZSA 1K3BB 2YJ8A 1NLJA 2GFOA 1BP4A 1MEGA 2WBFX 4OW0A 2FTDA 4W5BA 4CDDB 3H6SA 1AU2A 3LXSA 1IWDA 3BCNA 5CHTA 1GCBA 2AUXA 3MHHA 3O1GA 2AIMA
chains in the Genus database with same CATH topology
4PP2E 1DF0A 1ZIVA 2G8EA 3PNRA 3OF8A 5CVNB 4QRXA 1AECA 2E00A 3AI8A 1S4VA 1O0EA 2H7JA 2P0RA 1AU3A 4FIPA 5J94A 1AYVA 3I06A 2R9MA 1GMYA 3QJ3A 4I04A 3U8EA 3H89A 2YJ9A 1QMYA 2XU4A 1A6RA 3NHEA 4CDCB 5F02A 2B1MA 2NQIA 3ZUAA 4NV8A 1PPPA 2OP3A 1W6FA 3KWBX 2E02A 4I07A 1ICFA 1KFUL 2YJ2A 5CHVA 2PREA 3MTNA 2NQAA 1EWOA 7PCKA 4MZOA 1NB5A 4MSXA 1GX3A 3K9MA 2DZYA 3KWZA 1ATKA 8PCHA 2AS8A 4KLBA 1CVZA 2AYNA 2FQ9A 1YALA 4XR7A 2C0YA 2GHUA 4W4UA 1STFE 1Y4HA 3V6EA 3KW9A 4YV8A 1PADA 3OVZA 4AXLA 1AU4A 3BOWA 2G7YA 2FUDA 3C9EA 2AVWA 4CDFB 2DCBA 4GUZA 2Y6EA 2Y5BA 1CSBB 4ZUXU 5FPWA 2OZ2A 3KSEA 4W5CA 4N79A 2OULA 3TNXA 1KHQA 3IHPA 1TU6A 1VJVA 1W4TA 1TL9A 4Q8GA 2FRAA 2ARYA 3GCBA 2BDLA 1CB5A 1CJLA 2VHSA 4BSQA 4CDEB 2PNSA 2G6DA 3MHSA 3OVXA 2DCCA 3N3KA 2VFBA 1U9WA 1GECE 3LFYA 2JQGR 2DC6A 2B1NA 1X9YA 1VSNA 2BSZA 4I05A 1AYUA 2DC9A 3RVWA 5CVMA 4DMXA 2PADA 1AIMA 3O0UA 4BQVA 2E03A 2XU3A 4XUIA 3K8UA 3CBJA 4X6IA 2DJGB 2ACTA 4DMYA 4QH6A 4PP1A 3S3RA 1DEUA 1NL6A 1BQIA 3P5WA 1BGOA 1F2AA 4YYSA 2AYOA 2AUZA 1F29A 4X6JA 5PADA 2AU1A 3PBHA 1MIRA 1ITOA 4PI3A 3RVVA 4P6GA 1QOLA 4QRGA 4QRVA 4Q8HA 2ATOA 4P6EA 1U9QX 2E01A 3LTWA 3IEJA 3BPFA 1CQDA 3RVXA 3OF9A 3D6SA 3PDFA 4OEMA 4CZWA 1PPNA 2G8JA 1GLOA 5JH3A 3HHIA 1TLOA 2R9NA 4YYUA 1CPJA 3CH3X 1YK7A 5JA7A 4YVAA 3CH2X 1F2CA 2P7UA 3PW3A 1POPA 2FYEA 2HD5A 4FK5A 4BGFA 5A24A 1MHWA 2IBIA 1QXPA 4YYVA 3H8BA 1MS6A 3HHAA 2HH5A 1MDWA 2YJCA 1CV8A 1MEMA 1YT7A 1KHPA 1M6DA 3IMAA 2JQFR 2DC8A 1JQPA 1CS8A 2XU1A 1ZCMA 1SP4B 1KXRA 3F5VA 1PE6A 1YK8A 2HHNA 3B79A 3P5XA 4K7CA 1PBHA 1E2TA 2R9CA 3WXEA 4FJCA 1U5IA 2NQDB 1THEA 2IPPB 1PPOA 3USVA 3KX1A 3KFQA 1EF7A 3F75A 1NQCA 2CIOA 1XKGA 3H8CA 1Y08A 1EWMA 3WXGA 1AYWA 1CTEA 4HWYA 1PXVA 3P5UA 4G54A 4RY2A 1HUCB 2HXZA 3V6CA 2FRQA 4AXMA 4N8WA 3DF0A 3QSDA 2DC7A 2F1GA 1SNKA 3H7DA 3BWKA 1F2BA 4X6HA 4BS6A 1BY8A 2DCAA 3E1ZB 9PAPA 1AU0A 4YYWA 2FO5A 4YYQA 3S3QA 1U9VA 4C5PA 4B55A 3OISA 1QDQA 2DJFB 4WA6A 1PIPA 1NB3A 2NQGA 1Q6KA 5EGWA 3D9WA 3CBKA 5EF4A 4BS5A 2XU5A 2CB5A 3HD3A 3M99A 1FH0A 3ERVA 2VHFA 3BPMA 3I3TA 4OELA 2DZZA 3IUTA 1PPDA 4YYRA 1ME4A 1NPZA 2FT2A 6PADA 2DCDA 4N4ZA 3IV2A 1YVBA 1ME3A 2F7DA 3MORA 3N4CA 3QT4A 1U9XA 3BC3A 1W5RA 1PCIA 5K16A 2VFCA 4NV7A 2P86A 5CVOB 1EWPA 2R9FA 3N3GA 3K24A 3P5VA 3KKUA 3HWNA 2O6XA 2R9OA 1KFXL 4QBBA 1EWLA 3IOQA 2PBHA 3WXFA 4BPVA 2R6NA 4PADA 2BDZA 2YJBA 4MZSA 1K3BB 2YJ8A 1NLJA 2GFOA 1BP4A 1MEGA 2WBFX 4W5BA 2FTDA 4CDDB 3H6SA 1AU2A 3LXSA 1IWDA 3BCNA 5CHTA 1GCBA 2AUXA 3MHHA 3O1GA 2AIMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PP2 E;  1DF0 A;  1ZIV A;  2G8E A;  3PNR A;  3OF8 A;  5CVN B;  4QRX A;  1AEC A;  2E00 A;  3AI8 A;  1S4V A;  1O0E A;  2H7J A;  2P0R A;  1AU3 A;  4FIP A;  5J94 A;  1AYV A;  3I06 A;  2R9M A;  1GMY A;  3QJ3 A;  4I04 A;  3U8E A;  3H89 A;  2YJ9 A;  1QMY A;  2XU4 A;  1A6R A;  3NHE A;  4CDC B;  5F02 A;  2B1M A;  2NQI A;  3ZUA A;  1PPP A;  2OP3 A;  3KWB X;  2E02 A;  4I07 A;  1ICF A;  1KFU L;  2YJ2 A;  5CHV A;  2PRE A;  3MTN A;  2NQA A;  1EWO A;  7PCK A;  4MZO A;  1NB5 A;  4MSX A;  3K9M A;  2DZY A;  3KWZ A;  1ATK A;  8PCH A;  2AS8 A;  4KLB A;  1CVZ A;  2AYN A;  2FQ9 A;  1YAL A;  4XR7 A;  2C0Y A;  2GHU A;  4W4U A;  1STF E;  1Y4H A;  3V6E A;  3KW9 A;  4YV8 A;  1PAD A;  3OVZ A;  4AXL A;  1AU4 A;  3BOW A;  2G7Y A;  2FUD A;  3C9E A;  2AVW A;  4CDF B;  2DCB A;  2Y6E A;  2Y5B A;  1CSB B;  4ZUX U;  5FPW A;  2OZ2 A;  3KSE A;  4W5C A;  4N79 A;  2OUL A;  3TNX A;  1KHQ A;  3IHP A;  1TU6 A;  1VJV A;  1TL9 A;  4Q8G A;  2FRA A;  2ARY A;  3GCB A;  2BDL A;  1CB5 A;  1CJL A;  2VHS A;  4BSQ A;  4CDE B;  2PNS A;  2G6D A;  3MHS A;  3OVX A;  2DCC A;  3N3K A;  1U9W A;  1GEC E;  3LFY A;  2JQG R;  2DC6 A;  2B1N A;  1X9Y A;  1VSN A;  4I05 A;  1AYU A;  2DC9 A;  3RVW A;  5CVM A;  4DMX A;  2PAD A;  1AIM A;  3O0U A;  4BQV A;  2E03 A;  2XU3 A;  4XUI A;  3K8U A;  3CBJ A;  4X6I A;  2DJG B;  2ACT A;  4DMY A;  4QH6 A;  4PP1 A;  3S3R A;  1DEU A;  1NL6 A;  1BQI A;  3P5W A;  1BGO A;  1F2A A;  4YYS A;  2AYO A;  2AUZ A;  1F29 A;  4X6J A;  5PAD A;  2AU1 A;  3PBH A;  1MIR A;  1ITO A;  4PI3 A;  3RVV A;  4P6G A;  1QOL A;  4QRG A;  4QRV A;  4Q8H A;  2ATO A;  4P6E A;  1U9Q X;  2E01 A;  3IEJ A;  3BPF A;  1CQD A;  3RVX A;  3OF9 A;  3D6S A;  3PDF A;  4OEM A;  4CZW A;  1PPN A;  2G8J A;  1GLO A;  5JH3 A;  3HHI A;  1TLO A;  2R9N A;  4YYU A;  1CPJ A;  3CH3 X;  1YK7 A;  5JA7 A;  4YVA A;  3CH2 X;  1F2C A;  2P7U A;  3PW3 A;  1POP A;  2FYE A;  2HD5 A;  4FK5 A;  5A24 A;  1MHW A;  2IBI A;  1QXP A;  4YYV A;  3H8B A;  1MS6 A;  3HHA A;  2HH5 A;  1MDW A;  2YJC A;  1CV8 A;  1MEM A;  1YT7 A;  1KHP A;  1M6D A;  3IMA A;  2JQF R;  2DC8 A;  1JQP A;  1CS8 A;  2XU1 A;  1ZCM A;  1SP4 B;  1KXR A;  3F5V A;  1PE6 A;  1YK8 A;  2HHN A;  3B79 A;  3P5X A;  4K7C A;  1PBH A;  2R9C A;  3WXE A;  4FJC A;  1U5I A;  2NQD B;  1THE A;  2IPP B;  1PPO A;  3USV A;  3KX1 A;  3KFQ A;  1EF7 A;  3F75 A;  1NQC A;  2CIO A;  1XKG A;  3H8C A;  1Y08 A;  1EWM A;  3WXG A;  1AYW A;  1CTE A;  4HWY A;  1PXV A;  3P5U A;  4G54 A;  4RY2 A;  1HUC B;  2HXZ A;  3V6C A;  2FRQ A;  4AXM A;  4N8W A;  3DF0 A;  3QSD A;  2DC7 A;  2F1G A;  1SNK A;  3H7D A;  3BWK A;  1F2B A;  4X6H A;  4BS6 A;  1BY8 A;  2DCA A;  3E1Z B;  9PAP A;  1AU0 A;  4YYW A;  2FO5 A;  4YYQ A;  3S3Q A;  1U9V A;  3OIS A;  1QDQ A;  2DJF B;  4WA6 A;  1PIP A;  1NB3 A;  2NQG A;  1Q6K A;  5EGW A;  3CBK A;  5EF4 A;  4BS5 A;  2XU5 A;  2CB5 A;  3HD3 A;  3M99 A;  1FH0 A;  3ERV A;  2VHF A;  3BPM A;  3I3T A;  4OEL A;  2DZZ A;  3IUT A;  1PPD A;  4YYR A;  1ME4 A;  1NPZ A;  2FT2 A;  6PAD A;  2DCD A;  4N4Z A;  3IV2 A;  1YVB A;  1ME3 A;  2F7D A;  3MOR A;  3N4C A;  3QT4 A;  1U9X A;  3BC3 A;  1PCI A;  5K16 A;  2P86 A;  5CVO B;  1EWP A;  2R9F A;  3N3G A;  3K24 A;  3P5V A;  3KKU A;  3HWN A;  2O6X A;  2R9O A;  1KFX L;  4QBB A;  1EWL A;  3IOQ A;  2PBH A;  3WXF A;  4BPV A;  2R6N A;  4PAD A;  2BDZ A;  2YJB A;  4MZS A;  1K3B B;  2YJ8 A;  1NLJ A;  2GFO A;  1BP4 A;  1MEG A;  2WBF X;  4W5B A;  2FTD A;  4CDD B;  3H6S A;  1AU2 A;  3LXS A;  1IWD A;  3BCN A;  5CHT A;  1GCB A;  2AUX A;  3MHH A;  3O1G A;  2AIM A; 
#chains in the Genus database with same CATH topology
 4PP2 E;  3W30 A;  1DF0 A;  1ZIV A;  2G8E A;  3PNR A;  3OF8 A;  5CVN B;  4QRX A;  1AEC A;  2E00 A;  1PVJ A;  3AI8 A;  3BB7 A;  1S4V A;  1O0E A;  2H7J A;  2P0R A;  1AU3 A;  4FIP A;  4HXD B;  5J94 A;  1AYV A;  3BY4 A;  3I06 A;  2R9M A;  1GMY A;  3QJ3 A;  4I04 A;  3U8E A;  3H89 A;  2YJ9 A;  1QMY A;  2XU4 A;  1A6R A;  3NHE A;  4CDC B;  5F02 A;  2B1M A;  4IP3 A;  3PT2 A;  2JTC A;  2NQI A;  3ZUA A;  1PPP A;  2OP3 A;  5JZE A;  3KWB X;  2E02 A;  4I07 A;  1ICF A;  1KFU L;  4BOP A;  2YJ2 A;  5CHV A;  2PRE A;  3MTN A;  2NQA A;  1EWO A;  7PCK A;  4MZO A;  1NB5 A;  4MSX A;  3K9M A;  2DZY A;  3E9S A;  3KWZ A;  1ATK A;  1DKI A;  8PCH A;  2AS8 A;  4KLB A;  1CVZ A;  2AYN A;  2FQ9 A;  1YAL A;  4XR7 A;  2C0Y A;  2GHU A;  4W4U A;  1STF E;  1Y4H A;  3V6E A;  3KW9 A;  4YV8 A;  1PAD A;  3OVZ A;  4AXL A;  3OQC A;  1AU4 A;  4REZ A;  3BOW A;  2G7Y A;  2FUD A;  3C9E A;  2AVW A;  4CDF B;  2DCB A;  2Y6E A;  4D8I A;  2Y5B A;  3PRM A;  1CSB B;  4ZUX U;  5FPW A;  2OZ2 A;  3KSE A;  4W5C A;  4A5U A;  3W31 A;  4N79 A;  2OUL A;  3TNX A;  1KHQ A;  3IHP A;  1TU6 A;  1VJV A;  1TL9 A;  4Q8G A;  2FRA A;  2ARY A;  3GCB A;  2AGA A;  4OVZ A;  2BDL A;  4D8B A;  1CB5 A;  1CJL A;  2VHS A;  4BSQ A;  2BTW A;  4CDE B;  2PNS A;  2G6D A;  3MHS A;  3OVX A;  2DCC A;  3N3K A;  4RNA A;  2JRI A;  1U9W A;  1GEC E;  3LFY A;  3MTV A;  1UKF A;  3IFU A;  4RKX A;  2JQG R;  2DC6 A;  2B1N A;  1X9Y A;  1VSN A;  4I05 A;  1AYU A;  2DC9 A;  3RVW A;  5CVM A;  4DMX A;  2PAD A;  4PT5 A;  1AIM A;  5KO3 A;  3O0U A;  4BQV A;  2E03 A;  2XU3 A;  4XUI A;  3K8U A;  4D8E A;  3CBJ A;  4X6I A;  2DJG B;  2ACT A;  4DMY A;  4QH6 A;  4PP1 A;  3S3R A;  1DEU A;  1NL6 A;  3O65 A;  1BQI A;  3P5W A;  1BGO A;  1F2A A;  4YYS A;  2AYO A;  2AUZ A;  2FE8 A;  1F29 A;  3PHU A;  4X6J A;  5PAD A;  2AU1 A;  3PBH A;  3TMP A;  1MIR A;  4BOZ A;  1ITO A;  4PI3 A;  3RVV A;  4P6G A;  1QOL A;  4QRG A;  4QRV A;  3BBA A;  4Q8H A;  2ATO A;  4P6E A;  1U9Q X;  2E01 A;  3MP2 A;  3IEJ A;  3BPF A;  2Z84 A;  1CQD A;  3RVX A;  3OF9 A;  3D6S A;  3PDF A;  3B21 A;  4OEM A;  4CZW A;  1PPN A;  2G8J A;  1GLO A;  5JH3 A;  3HHI A;  4GUA A;  1TLO A;  2R9N A;  4YYU A;  1CPJ A;  3CH3 X;  1YK7 A;  5JA7 A;  4YVA A;  3CH2 X;  1F2C A;  2P7U A;  3PW3 A;  1POP A;  2FYE A;  2HD5 A;  4FK5 A;  5A24 A;  4M0W A;  1MHW A;  2IBI A;  4MI7 A;  1QXP A;  4YYV A;  3H8B A;  1MS6 A;  3HHA A;  4R3D A;  4BOQ A;  2HH5 A;  1MDW A;  3C0R A;  2YJC A;  1CV8 A;  1MEM A;  1YT7 A;  1KHP A;  1M6D A;  4IUM A;  1YZB A;  3IMA A;  2JQF R;  2DC8 A;  1JQP A;  1CS8 A;  2XU1 A;  1ZCM A;  3TRK A;  1SP4 B;  1KXR A;  3F5V A;  1PE6 A;  1YK8 A;  2HHN A;  3B79 A;  3P5X A;  5E6J A;  4K7C A;  1PBH A;  2R9C A;  3WXE A;  4FJC A;  1U5I A;  2NQD B;  1THE A;  2HWK A;  2IPP B;  1PPO A;  5EZS A;  3USV A;  3KX1 A;  3KFQ A;  1EF7 A;  3F75 A;  1NQC A;  2CIO A;  1XKG A;  3H8C A;  1Y08 A;  4BOS A;  1EWM A;  3WXG A;  1AYW A;  1CTE A;  2J7Q A;  3PHX A;  4HWY A;  1PXV A;  3P5U A;  4ZTB A;  4G54 A;  4RY2 A;  1HUC B;  2HXZ A;  3V6C A;  2FRQ A;  4AXM A;  2UZJ A;  4N8W A;  3DF0 A;  3QSD A;  2DC7 A;  2F1G A;  1SNK A;  4WUR A;  3H7D A;  3BWK A;  1F2B A;  5EZQ A;  4X6H A;  4BS6 A;  1BY8 A;  2DCA A;  3E1Z B;  9PAP A;  1AU0 A;  4OVZ B;  4YYW A;  2FO5 A;  4YYQ A;  3S3Q A;  1U9V A;  3OIS A;  2BTW B;  1QDQ A;  2DJF B;  4WA6 A;  1PIP A;  1NB3 A;  2NQG A;  1Q6K A;  5EGW A;  3CBK A;  4MM3 B;  5EF4 A;  4RF1 A;  4BS5 A;  2XU5 A;  2CB5 A;  3HD3 A;  3M99 A;  3PHW A;  1FH0 A;  3ERV A;  2VHF A;  3BPM A;  3I3T A;  4P16 A;  4OEL A;  2DZZ A;  2J7Q C;  3RNV A;  4XZX A;  3IUT A;  1PPD A;  4YYR A;  1ME4 A;  1NPZ A;  2FT2 A;  6PAD A;  3PRP A;  2DCD A;  2DOS A;  4N4Z A;  3IV2 A;  1YVB A;  1ME3 A;  2F7D A;  3MOR A;  3N4C A;  3QT4 A;  1U9X A;  3BC3 A;  1PCI A;  5K16 A;  2P86 A;  3ZNH A;  5CVO B;  1EWP A;  2R9F A;  3N3G A;  3K24 A;  4RF0 A;  3P5V A;  3KKU A;  2BU3 A;  3HWN A;  2O6X A;  2R9O A;  1KFX L;  4QBB A;  1EWL A;  3IOQ A;  3PSE A;  2PBH A;  4BOU A;  3WXF A;  4BPV A;  2R6N A;  4PAD A;  3MJ5 A;  2BDZ A;  2YJB A;  4MZS A;  1K3B B;  2YJ8 A;  1NLJ A;  2GFO A;  1BP4 A;  1MEG A;  2WBF X;  4OW0 A;  2FTD A;  4W5B A;  4CDD B;  3H6S A;  1AU2 A;  3LXS A;  1IWD A;  3BCN A;  5CHT A;  1GCB A;  2AUX A;  3MHH A;  3O1G A;  2AIM A; 
#chains in the Genus database with same CATH homology
 4PP2 E;  1DF0 A;  1ZIV A;  2G8E A;  3PNR A;  3OF8 A;  5CVN B;  4QRX A;  1AEC A;  2E00 A;  3AI8 A;  1S4V A;  1O0E A;  2H7J A;  2P0R A;  1AU3 A;  4FIP A;  5J94 A;  1AYV A;  3I06 A;  2R9M A;  1GMY A;  3QJ3 A;  4I04 A;  3U8E A;  3H89 A;  2YJ9 A;  1QMY A;  2XU4 A;  1A6R A;  3NHE A;  4CDC B;  5F02 A;  2B1M A;  2NQI A;  3ZUA A;  4NV8 A;  1PPP A;  2OP3 A;  1W6F A;  3KWB X;  2E02 A;  4I07 A;  1ICF A;  1KFU L;  2YJ2 A;  5CHV A;  2PRE A;  3MTN A;  2NQA A;  1EWO A;  7PCK A;  4MZO A;  1NB5 A;  4MSX A;  1GX3 A;  3K9M A;  2DZY A;  3KWZ A;  1ATK A;  8PCH A;  2AS8 A;  4KLB A;  1CVZ A;  2AYN A;  2FQ9 A;  1YAL A;  4XR7 A;  2C0Y A;  2GHU A;  4W4U A;  1STF E;  1Y4H A;  3V6E A;  3KW9 A;  4YV8 A;  1PAD A;  3OVZ A;  4AXL A;  1AU4 A;  3BOW A;  2G7Y A;  2FUD A;  3C9E A;  2AVW A;  4CDF B;  2DCB A;  4GUZ A;  2Y6E A;  2Y5B A;  1CSB B;  4ZUX U;  5FPW A;  2OZ2 A;  3KSE A;  4W5C A;  4N79 A;  2OUL A;  3TNX A;  1KHQ A;  3IHP A;  1TU6 A;  1VJV A;  1W4T A;  1TL9 A;  4Q8G A;  2FRA A;  2ARY A;  3GCB A;  2BDL A;  1CB5 A;  1CJL A;  2VHS A;  4BSQ A;  4CDE B;  2PNS A;  2G6D A;  3MHS A;  3OVX A;  2DCC A;  3N3K A;  2VFB A;  1U9W A;  1GEC E;  3LFY A;  2JQG R;  2DC6 A;  2B1N A;  1X9Y A;  1VSN A;  2BSZ A;  4I05 A;  1AYU A;  2DC9 A;  3RVW A;  5CVM A;  4DMX A;  2PAD A;  1AIM A;  3O0U A;  4BQV A;  2E03 A;  2XU3 A;  4XUI A;  3K8U A;  3CBJ A;  4X6I A;  2DJG B;  2ACT A;  4DMY A;  4QH6 A;  4PP1 A;  3S3R A;  1DEU A;  1NL6 A;  1BQI A;  3P5W A;  1BGO A;  1F2A A;  4YYS A;  2AYO A;  2AUZ A;  1F29 A;  4X6J A;  5PAD A;  2AU1 A;  3PBH A;  1MIR A;  1ITO A;  4PI3 A;  3RVV A;  4P6G A;  1QOL A;  4QRG A;  4QRV A;  4Q8H A;  2ATO A;  4P6E A;  1U9Q X;  2E01 A;  3LTW A;  3IEJ A;  3BPF A;  1CQD A;  3RVX A;  3OF9 A;  3D6S A;  3PDF A;  4OEM A;  4CZW A;  1PPN A;  2G8J A;  1GLO A;  5JH3 A;  3HHI A;  1TLO A;  2R9N A;  4YYU A;  1CPJ A;  3CH3 X;  1YK7 A;  5JA7 A;  4YVA A;  3CH2 X;  1F2C A;  2P7U A;  3PW3 A;  1POP A;  2FYE A;  2HD5 A;  4FK5 A;  4BGF A;  5A24 A;  1MHW A;  2IBI A;  1QXP A;  4YYV A;  3H8B A;  1MS6 A;  3HHA A;  2HH5 A;  1MDW A;  2YJC A;  1CV8 A;  1MEM A;  1YT7 A;  1KHP A;  1M6D A;  3IMA A;  2JQF R;  2DC8 A;  1JQP A;  1CS8 A;  2XU1 A;  1ZCM A;  1SP4 B;  1KXR A;  3F5V A;  1PE6 A;  1YK8 A;  2HHN A;  3B79 A;  3P5X A;  4K7C A;  1PBH A;  1E2T A;  2R9C A;  3WXE A;  4FJC A;  1U5I A;  2NQD B;  1THE A;  2IPP B;  1PPO A;  3USV A;  3KX1 A;  3KFQ A;  1EF7 A;  3F75 A;  1NQC A;  2CIO A;  1XKG A;  3H8C A;  1Y08 A;  1EWM A;  3WXG A;  1AYW A;  1CTE A;  4HWY A;  1PXV A;  3P5U A;  4G54 A;  4RY2 A;  1HUC B;  2HXZ A;  3V6C A;  2FRQ A;  4AXM A;  4N8W A;  3DF0 A;  3QSD A;  2DC7 A;  2F1G A;  1SNK A;  3H7D A;  3BWK A;  1F2B A;  4X6H A;  4BS6 A;  1BY8 A;  2DCA A;  3E1Z B;  9PAP A;  1AU0 A;  4YYW A;  2FO5 A;  4YYQ A;  3S3Q A;  1U9V A;  4C5P A;  4B55 A;  3OIS A;  1QDQ A;  2DJF B;  4WA6 A;  1PIP A;  1NB3 A;  2NQG A;  1Q6K A;  5EGW A;  3D9W A;  3CBK A;  5EF4 A;  4BS5 A;  2XU5 A;  2CB5 A;  3HD3 A;  3M99 A;  1FH0 A;  3ERV A;  2VHF A;  3BPM A;  3I3T A;  4OEL A;  2DZZ A;  3IUT A;  1PPD A;  4YYR A;  1ME4 A;  1NPZ A;  2FT2 A;  6PAD A;  2DCD A;  4N4Z A;  3IV2 A;  1YVB A;  1ME3 A;  2F7D A;  3MOR A;  3N4C A;  3QT4 A;  1U9X A;  3BC3 A;  1W5R A;  1PCI A;  5K16 A;  2VFC A;  4NV7 A;  2P86 A;  5CVO B;  1EWP A;  2R9F A;  3N3G A;  3K24 A;  3P5V A;  3KKU A;  3HWN A;  2O6X A;  2R9O A;  1KFX L;  4QBB A;  1EWL A;  3IOQ A;  2PBH A;  3WXF A;  4BPV A;  2R6N A;  4PAD A;  2BDZ A;  2YJB A;  4MZS A;  1K3B B;  2YJ8 A;  1NLJ A;  2GFO A;  1BP4 A;  1MEG A;  2WBF X;  4W5B A;  2FTD A;  4CDD B;  3H6S A;  1AU2 A;  3LXS A;  1IWD A;  3BCN A;  5CHT A;  1GCB A;  2AUX A;  3MHH A;  3O1G A;  2AIM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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