4QRGA

Crystal structure of i86l mutant of papain
Total Genus 110
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
110
sequence length
316
structure length
300
Chain Sequence
IVGYSQNDLTSTERLIQLFESWMLKHNKIYKNIDEKIYRFEIFKDNLKYIDETNKKNNSYWLGLNVFADMSNDEFKEKYTGSLAGNVNIPEYVDWRQKGAVTPVKNQGSCGSAWAFSAVSTIESIIKIRTGNLNEYSEQELLDCDRRSYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKTDGVRQVQPYNEGALLYSIANQPVSVVLEAAGKDFQLYRGGIFVGPCGNKVDHAVAAVGYGPNYILIRNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPVKN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Pro-peptide regulates the substrate specificity and zymogen activation process of papain: A structural and mechanistic insight
rcsb
molecule keywords Papain
molecule tags Hydrolase
source organism Carica papaya
total genus 110
structure length 300
sequence length 316
chains with identical sequence B
ec nomenclature ec 3.4.22.2: Papain.
pdb deposition date 2014-07-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
A PF08246 Inhibitor_I29 Cathepsin propeptide inhibitor domain (I29)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 4qrgA00
3PNRA 3CH2X 1PPNA 2AYNA 4N4ZA 1U9QX 4QRVA 4X6HA 2IBIA 2R9FA 4Q8HA 1NQCA 3HHIA 5J94A 3MTNA 1DF0A 5FPWA 1F2AA 1Q6KA 1U9VA 3DF0A 1KHQA 2E01A 4MZOA 2P86A 2FRQA 3QJ3A 1NLJA 1F2CA 1S4VA 2R9NA 2B1NA 1CPJA 4YYQA 4YV8A 3N3GA 2NQAA 4BSQA 2DZYA 3CBKA 4QRGA 2XU5A 3PW3A 3IV2A 1PCIA 2DZZA 1QDQA 3IMAA 2Y5BA 9PAPA 2PNSA 2O6XA 2NQIA 1AU2A 3C9EA 2E00A 1SNKA 3F5VA 2F1GA 2DCDA 3BPMA 3LXSA 1A6RA 2R9CA 3K8UA 4MSXA 4I07A 3OVZA 2HXZA 1X9YA 1QMYA 3QT4A 3RVWA 1PADA 3MORA 2OULA 5CVNB 3HWNA 4CDFB 4BS6A 4ZUXU 3HD3A 3PDFA 3V6CA 3K24A 4XR7A 1U9WA 4Q8GA 4PI3A 4N8WA 3U8EA 1AYVA 1ITOA 5PADA 1EWLA 4P6GA 1XKGA 5JA7A 4YYUA 1PBHA 3I3TA 1STFE 4I04A 6PADA 1EWMA 2R6NA 1JQPA 3S3QA 8PCHA 1YK8A 1Y08A 2VHSA 1AU0A 2DCBA 3RVVA 1AYWA 4QH6A 1DEUA 4X6JA 4W5BA 4BQVA 1MS6A 2GHUA 3IUTA 2P7UA 2DCAA 4YYSA 1TU6A 2YJ9A 1YVBA 2P0RA 1KHPA 1GECE 2R9OA 2DJGB 5CHVA 4FJCA 1U9XA 3I06A 1CVZA 1AYUA 1AIMA 1CB5A 3ERVA 1F2BA 4AXMA 1PPOA 5EF4A 4MZSA 3MHSA 1U5IA 5F02A 4W4UA 4X6IA 1CSBB 2FYEA 1ATKA 2YJBA 1ZIVA 2FTDA 4QBBA 2VHFA 2F7DA 4HWYA 3O1GA 5EGWA 1EF7A 1NPZA 3GCBA 3PBHA 4DMXA 2YJCA 4XUIA 2XU1A 1POPA 1Y4HA 3BWKA 2XU3A 4OEMA 2OZ2A 3N4CA 3KFQA 1YT7A 1PE6A 1THEA 1CTEA 2C0YA 2DC7A 3WXFA 2JQGR 4YYRA 4CDDB 2PADA 3H89A 1MIRA 1TLOA 2G6DA 5A24A 3KKUA 4QRXA 4WA6A 1MEMA 2CB5A 2FUDA 1ZCMA 5CVMA 3HHAA 5JH3A 1AU4A 2AS8A 2XU4A 1FH0A 2G7YA 1EWOA 3H8BA 3BPFA 3KSEA 4RY2A 1QOLA 4P6EA 2BDLA 3KWBX 3K9MA 2E02A 3QSDA 4W5CA 4FK5A 1NB5A 3IEJA 1PPPA 1PIPA 2G8JA 1KXRA 4KLBA 4I05A 2HD5A 1VJVA 2DC8A 4G54A 3AI8A 3BCNA 3KX1A 3USVA 2DC6A 2AIMA 1TL9A 3OVXA 2FO5A 1SP4B 1BY8A 3OF9A 4BPVA 2B1MA 1KFUL 7PCKA 2OP3A 1GMYA 1ME4A 2NQDB 1MDWA 3P5XA 2AUZA 2HH5A 3OF8A 1CV8A 3TNXA 2GFOA 1IWDA 3LFYA 2FT2A 4YYVA 2DJFB 4AXLA 2YJ8A 1YALA 2AU1A 3E1ZB 1YK7A 4CDCB 3NHEA 1VSNA 3BC3A 2HHNA 2PBHA 1ME3A 3V6EA 4OELA 1EWPA 1AU3A 1K3BB 1BQIA 3MHHA 1O0EA 2JQFR 3B79A 5CVOB 1ICFA 1CJLA 3KW9A 4BS5A 3P5WA 3ZUAA 2WBFX 2YJ2A 3WXEA 4PADA 4K7CA 3S3RA 3IOQA 1BP4A 2DC9A 2PREA 2IPPB 3RVXA 2AYOA 3H7DA 2CIOA 3OISA 3O0UA 2FRAA 4PP1A 4N79A 1GLOA 3IHPA 4FIPA 1KFXL 2ATOA 4DMYA 1MEGA 3M99A 1HUCB 3D6SA 4CDEB 3H6SA 3CBJA 5K16A 1GCBA 3BOWA 1CS8A 3H8CA 4YYWA 4PP2E 2DCCA 2BDZA 1CQDA 2NQGA 1M6DA 1F29A 2E03A 1MHWA 3WXGA 4CZWA 2R9MA 2G8EA 2Y6EA 3CH3X 2AVWA 1PXVA 2ACTA 1AECA 3P5UA 1NL6A 1NB3A 3N3KA 1QXPA 2AUXA 3KWZA 5CHTA 1BGOA 2ARYA 4YVAA 3F75A 2FQ9A 3P5VA 1PPDA 2H7JA
chains in the Genus database with same CATH superfamily
3PNRA 3CH2X 1PPNA 1DKIA 2AYNA 4N4ZA 1U9QX 4QRVA 4X6HA 2IBIA 2R9FA 4Q8HA 1NQCA 3HHIA 5J94A 3MTNA 1DF0A 5FPWA 3OQCA 4GUAA 1F2AA 1Q6KA 1U9VA 3DF0A 4MM3B 1YZBA 1KHQA 2E01A 4MZOA 2DOSA 2P86A 4D8IA 2FRQA 3QJ3A 1NLJA 1F2CA 1S4VA 2R9NA 2B1NA 1CPJA 4YYQA 4YV8A 2UZJA 3N3GA 2NQAA 3MJ5A 4BSQA 2DZYA 3CBKA 3PRMA 4QRGA 1UKFA 2XU5A 3PW3A 3PSEA 3IV2A 1PCIA 2DZZA 1QDQA 3IMAA 2Y5BA 9PAPA 2PNSA 4ZTBA 2O6XA 2NQIA 1AU2A 3C9EA 4A5UA 2E00A 1SNKA 3F5VA 2F1GA 3PT2A 2DCDA 3BPMA 3LXSA 1A6RA 2R9CA 4D8BA 3K8UA 4MSXA 4I07A 3OVZA 2HXZA 1X9YA 2J7QC 3RNVA 1QMYA 3QT4A 3RVWA 1PADA 3MORA 2OULA 5CVNB 3HWNA 4CDFB 4BS6A 4ZUXU 2JTCA 3HD3A 3PDFA 3V6CA 3K24A 4XR7A 1U9WA 4Q8GA 4PI3A 4N8WA 4WURA 3U8EA 1AYVA 1ITOA 5PADA 1EWLA 4P6GA 3W31A 1XKGA 5JA7A 4YYUA 1PBHA 3I3TA 4RF1A 1STFE 4I04A 6PADA 1EWMA 2R6NA 1JQPA 3S3QA 8PCHA 1YK8A 1Y08A 2VHSA 1AU0A 3PHXA 2DCBA 4HXDB 3RVVA 1AYWA 4QH6A 1DEUA 4X6JA 4W5BA 4OW0A 4BQVA 4BOQA 1MS6A 2GHUA 3IUTA 2P7UA 2DCAA 4YYSA 1TU6A 2YJ9A 1YVBA 2P0RA 1KHPA 1GECE 2R9OA 2DJGB 5CHVA 4FJCA 1U9XA 3I06A 1CVZA 1AYUA 1AIMA 1CB5A 3ERVA 4IP3A 1F2BA 4MI7A 5JZEA 4AXMA 4OVZB 1PPOA 5EF4A 2BTWB 4MZSA 3MHSA 4BOZA 1U5IA 5F02A 2AGAA 4W4UA 4X6IA 1CSBB 2FYEA 4PT5A 1ATKA 2YJBA 1ZIVA 2FTDA 4M0WA 4QBBA 2VHFA 2F7DA 2JRIA 3O1GA 4HWYA 4IUMA 1EF7A 1NPZA 3GCBA 5EGWA 3PBHA 4DMXA 2YJCA 4XUIA 2XU1A 1POPA 1Y4HA 3BWKA 2XU3A 4OEMA 2OZ2A 3N4CA 3KFQA 1YT7A 1PE6A 3PRPA 1THEA 1CTEA 4OVZA 2C0YA 2DC7A 3WXFA 2JQGR 4YYRA 2BTWA 4P16A 4BOUA 4CDDB 2PADA 3H89A 1MIRA 1TLOA 2G6DA 4BOPA 5A24A 3PHWA 3KKUA 4QRXA 4WA6A 1MEMA 2CB5A 2FUDA 3TRKA 1ZCMA 5CVMA 3HHAA 5JH3A 3PHUA 1AU4A 2BU3A 2AS8A 2XU4A 1FH0A 2G7YA 1EWOA 3H8BA 5EZQA 3BPFA 3KSEA 4RY2A 1QOLA 4P6EA 2Z84A 3MP2A 2BDLA 3KWBX 3BBAA 3K9MA 2E02A 3QSDA 4W5CA 4FK5A 5E6JA 1NB5A 3IEJA 3W30A 1PPPA 5EZSA 1PIPA 2G8JA 1KXRA 4KLBA 4I05A 2HD5A 1VJVA 2DC8A 4G54A 3AI8A 3BCNA 3KX1A 3USVA 2DC6A 2AIMA 3B21A 1TL9A 3OVXA 2FO5A 1SP4B 1BY8A 3OF9A 4BPVA 2B1MA 1KFUL 7PCKA 2OP3A 1GMYA 1ME4A 2NQDB 1MDWA 3P5XA 2AUZA 2HH5A 3OF8A 4D8EA 4R3DA 1CV8A 3TNXA 2GFOA 1IWDA 2J7QA 3LFYA 3BB7A 2FT2A 4YYVA 2DJFB 4AXLA 2YJ8A 1YALA 2AU1A 3E1ZB 1YK7A 4CDCB 3NHEA 1VSNA 3BC3A 2HHNA 2PBHA 1ME3A 3V6EA 4OELA 1EWPA 1AU3A 1K3BB 1PVJA 1BQIA 3MHHA 1O0EA 2JQFR 3MTVA 3B79A 5CVOB 1ICFA 1CJLA 4XZXA 3IFUA 3KW9A 4BS5A 3P5WA 3ZUAA 2WBFX 2YJ2A 3WXEA 5KO3A 4PADA 4K7CA 3S3RA 3E9SA 3ZNHA 3IOQA 1BP4A 2DC9A 2PREA 2IPPB 3RVXA 2AYOA 3H7DA 2CIOA 3OISA 3O0UA 2FRAA 4PP1A 4N79A 1GLOA 3IHPA 4RKXA 4FIPA 1KFXL 3C0RA 2ATOA 4DMYA 1MEGA 3M99A 1HUCB 3D6SA 4CDEB 3H6SA 3CBJA 5K16A 1GCBA 3BOWA 1CS8A 3H8CA 4YYWA 4RF0A 4PP2E 2DCCA 4BOSA 2BDZA 1CQDA 2NQGA 1M6DA 1F29A 2E03A 1MHWA 3WXGA 4CZWA 2R9MA 3BY4A 2G8EA 2Y6EA 3CH3X 3TMPA 2AVWA 4REZA 1PXVA 2ACTA 1AECA 3P5UA 3O65A 1NL6A 1NB3A 3N3KA 1QXPA 2AUXA 3KWZA 5CHTA 1BGOA 2ARYA 4YVAA 3F75A 2FQ9A 4RNAA 2HWKA 3P5VA 1PPDA 2H7JA 2FE8A
chains in the Genus database with same CATH topology
3PNRA 3CH2X 1PPNA 2AYNA 4N4ZA 1U9QX 4QRVA 4X6HA 2IBIA 2R9FA 4Q8HA 1NQCA 3HHIA 5J94A 3MTNA 1DF0A 5FPWA 1F2AA 1Q6KA 1U9VA 3DF0A 1KHQA 2E01A 4MZOA 2P86A 2FRQA 3QJ3A 1NLJA 1F2CA 1S4VA 2R9NA 2B1NA 1CPJA 4YYQA 4YV8A 3N3GA 2NQAA 4BSQA 2DZYA 3CBKA 4QRGA 2XU5A 3PW3A 3IV2A 1PCIA 2DZZA 1QDQA 3IMAA 2Y5BA 4GUZA 9PAPA 2PNSA 2O6XA 2NQIA 1AU2A 2BSZA 3C9EA 2E00A 1SNKA 3F5VA 2F1GA 2DCDA 3BPMA 3LXSA 1A6RA 2R9CA 4NV7A 1W6FA 3K8UA 4MSXA 4I07A 3OVZA 2HXZA 1X9YA 1QMYA 3QT4A 3RVWA 1PADA 3MORA 2OULA 5CVNB 3HWNA 4CDFB 4BS6A 4ZUXU 3HD3A 3PDFA 3V6CA 3K24A 4XR7A 1U9WA 4Q8GA 4PI3A 4N8WA 3U8EA 1AYVA 1ITOA 5PADA 1EWLA 4P6GA 1XKGA 5JA7A 4YYUA 1PBHA 3I3TA 4BGFA 1STFE 4I04A 6PADA 1EWMA 2R6NA 1JQPA 3S3QA 8PCHA 1YK8A 1Y08A 2VHSA 1AU0A 2DCBA 3RVVA 1AYWA 4QH6A 1DEUA 4X6JA 4W5BA 4BQVA 4C5PA 1MS6A 2GHUA 2VFCA 3IUTA 2P7UA 2DCAA 4YYSA 1TU6A 2YJ9A 1YVBA 2P0RA 1KHPA 1GECE 2R9OA 2DJGB 5CHVA 4FJCA 1U9XA 3I06A 1CVZA 1AYUA 1AIMA 1CB5A 3ERVA 1F2BA 4AXMA 1PPOA 5EF4A 1W5RA 4MZSA 3MHSA 1U5IA 5F02A 4W4UA 4X6IA 1CSBB 2FYEA 1ATKA 2YJBA 1ZIVA 2FTDA 4QBBA 2VHFA 2F7DA 4HWYA 3O1GA 5EGWA 1EF7A 1NPZA 3GCBA 3PBHA 4DMXA 2YJCA 3D9WA 4XUIA 2XU1A 1POPA 4B55A 1Y4HA 3BWKA 2XU3A 4OEMA 2OZ2A 3N4CA 3KFQA 1YT7A 1PE6A 1THEA 1CTEA 2C0YA 2DC7A 3WXFA 2JQGR 4YYRA 4CDDB 2PADA 3H89A 1MIRA 1TLOA 2G6DA 5A24A 3KKUA 4QRXA 4WA6A 1MEMA 1GX3A 2CB5A 2FUDA 1ZCMA 5CVMA 3HHAA 5JH3A 1AU4A 2AS8A 2XU4A 1FH0A 2G7YA 1EWOA 3H8BA 3BPFA 3KSEA 4RY2A 1QOLA 4P6EA 2BDLA 3KWBX 3K9MA 2E02A 3QSDA 4W5CA 4FK5A 1NB5A 3IEJA 1PPPA 1PIPA 2G8JA 1KXRA 4KLBA 4I05A 2HD5A 1VJVA 2DC8A 4G54A 3AI8A 3BCNA 3KX1A 3USVA 2DC6A 2AIMA 1TL9A 3OVXA 2FO5A 1SP4B 1BY8A 3OF9A 4BPVA 2B1MA 1KFUL 4NV8A 7PCKA 2OP3A 1GMYA 1ME4A 2NQDB 1MDWA 3LTWA 3P5XA 2AUZA 2HH5A 3OF8A 1CV8A 3TNXA 2GFOA 1IWDA 3LFYA 2FT2A 4YYVA 2DJFB 4AXLA 2YJ8A 1YALA 2AU1A 3E1ZB 1YK7A 4CDCB 3NHEA 1VSNA 3BC3A 2HHNA 2PBHA 1ME3A 3V6EA 4OELA 1EWPA 1AU3A 1K3BB 1BQIA 3MHHA 1O0EA 2JQFR 3B79A 5CVOB 1ICFA 1CJLA 3KW9A 4BS5A 3P5WA 3ZUAA 2WBFX 2YJ2A 3WXEA 4PADA 4K7CA 3S3RA 3IOQA 1BP4A 2DC9A 2PREA 2IPPB 3RVXA 2VFBA 2AYOA 3H7DA 2CIOA 3OISA 3O0UA 2FRAA 4PP1A 4N79A 1GLOA 3IHPA 4FIPA 1KFXL 2ATOA 4DMYA 1MEGA 3M99A 1HUCB 3D6SA 4CDEB 3H6SA 3CBJA 5K16A 1GCBA 3BOWA 1CS8A 3H8CA 4YYWA 4PP2E 2DCCA 2BDZA 1CQDA 2NQGA 1M6DA 1W4TA 1F29A 2E03A 1MHWA 3WXGA 4CZWA 2R9MA 2G8EA 2Y6EA 3CH3X 2AVWA 1PXVA 2ACTA 1AECA 3P5UA 1NL6A 1NB3A 1E2TA 3N3KA 1QXPA 2AUXA 3KWZA 5CHTA 1BGOA 2ARYA 4YVAA 3F75A 2FQ9A 3P5VA 1PPDA 2H7JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PNR A;  3CH2 X;  1PPN A;  2AYN A;  4N4Z A;  1U9Q X;  4QRV A;  4X6H A;  2IBI A;  2R9F A;  4Q8H A;  1NQC A;  3HHI A;  5J94 A;  3MTN A;  1DF0 A;  5FPW A;  1F2A A;  1Q6K A;  1U9V A;  3DF0 A;  1KHQ A;  2E01 A;  4MZO A;  2P86 A;  2FRQ A;  3QJ3 A;  1NLJ A;  1F2C A;  1S4V A;  2R9N A;  2B1N A;  1CPJ A;  4YYQ A;  4YV8 A;  3N3G A;  2NQA A;  4BSQ A;  2DZY A;  3CBK A;  4QRG A;  2XU5 A;  3PW3 A;  3IV2 A;  1PCI A;  2DZZ A;  1QDQ A;  3IMA A;  2Y5B A;  9PAP A;  2PNS A;  2O6X A;  2NQI A;  1AU2 A;  3C9E A;  2E00 A;  1SNK A;  3F5V A;  2F1G A;  2DCD A;  3BPM A;  3LXS A;  1A6R A;  2R9C A;  3K8U A;  4MSX A;  4I07 A;  3OVZ A;  2HXZ A;  1X9Y A;  1QMY A;  3QT4 A;  3RVW A;  1PAD A;  3MOR A;  2OUL A;  5CVN B;  3HWN A;  4CDF B;  4BS6 A;  4ZUX U;  3HD3 A;  3PDF A;  3V6C A;  3K24 A;  4XR7 A;  1U9W A;  4Q8G A;  4PI3 A;  4N8W A;  3U8E A;  1AYV A;  1ITO A;  5PAD A;  1EWL A;  4P6G A;  1XKG A;  5JA7 A;  4YYU A;  1PBH A;  3I3T A;  1STF E;  4I04 A;  6PAD A;  1EWM A;  2R6N A;  1JQP A;  3S3Q A;  8PCH A;  1YK8 A;  1Y08 A;  2VHS A;  1AU0 A;  2DCB A;  3RVV A;  1AYW A;  4QH6 A;  1DEU A;  4X6J A;  4W5B A;  4BQV A;  1MS6 A;  2GHU A;  3IUT A;  2P7U A;  2DCA A;  4YYS A;  1TU6 A;  2YJ9 A;  1YVB A;  2P0R A;  1KHP A;  1GEC E;  2R9O A;  2DJG B;  5CHV A;  4FJC A;  1U9X A;  3I06 A;  1CVZ A;  1AYU A;  1AIM A;  1CB5 A;  3ERV A;  1F2B A;  4AXM A;  1PPO A;  5EF4 A;  4MZS A;  3MHS A;  1U5I A;  5F02 A;  4W4U A;  4X6I A;  1CSB B;  2FYE A;  1ATK A;  2YJB A;  1ZIV A;  2FTD A;  4QBB A;  2VHF A;  2F7D A;  4HWY A;  3O1G A;  5EGW A;  1EF7 A;  1NPZ A;  3GCB A;  3PBH A;  4DMX A;  2YJC A;  4XUI A;  2XU1 A;  1POP A;  1Y4H A;  3BWK A;  2XU3 A;  4OEM A;  2OZ2 A;  3N4C A;  3KFQ A;  1YT7 A;  1PE6 A;  1THE A;  1CTE A;  2C0Y A;  2DC7 A;  3WXF A;  2JQG R;  4YYR A;  4CDD B;  2PAD A;  3H89 A;  1MIR A;  1TLO A;  2G6D A;  5A24 A;  3KKU A;  4QRX A;  4WA6 A;  1MEM A;  2CB5 A;  2FUD A;  1ZCM A;  5CVM A;  3HHA A;  5JH3 A;  1AU4 A;  2AS8 A;  2XU4 A;  1FH0 A;  2G7Y A;  1EWO A;  3H8B A;  3BPF A;  3KSE A;  4RY2 A;  1QOL A;  4P6E A;  2BDL A;  3KWB X;  3K9M A;  2E02 A;  3QSD A;  4W5C A;  4FK5 A;  1NB5 A;  3IEJ A;  1PPP A;  1PIP A;  2G8J A;  1KXR A;  4KLB A;  4I05 A;  2HD5 A;  1VJV A;  2DC8 A;  4G54 A;  3AI8 A;  3BCN A;  3KX1 A;  3USV A;  2DC6 A;  2AIM A;  1TL9 A;  3OVX A;  2FO5 A;  1SP4 B;  1BY8 A;  3OF9 A;  4BPV A;  2B1M A;  1KFU L;  7PCK A;  2OP3 A;  1GMY A;  1ME4 A;  2NQD B;  1MDW A;  3P5X A;  2AUZ A;  2HH5 A;  3OF8 A;  1CV8 A;  3TNX A;  2GFO A;  1IWD A;  3LFY A;  2FT2 A;  4YYV A;  2DJF B;  4AXL A;  2YJ8 A;  1YAL A;  2AU1 A;  3E1Z B;  1YK7 A;  4CDC B;  3NHE A;  1VSN A;  3BC3 A;  2HHN A;  2PBH A;  1ME3 A;  3V6E A;  4OEL A;  1EWP A;  1AU3 A;  1K3B B;  1BQI A;  3MHH A;  1O0E A;  2JQF R;  3B79 A;  5CVO B;  1ICF A;  1CJL A;  3KW9 A;  4BS5 A;  3P5W A;  3ZUA A;  2WBF X;  2YJ2 A;  3WXE A;  4PAD A;  4K7C A;  3S3R A;  3IOQ A;  1BP4 A;  2DC9 A;  2PRE A;  2IPP B;  3RVX A;  2AYO A;  3H7D A;  2CIO A;  3OIS A;  3O0U A;  2FRA A;  4PP1 A;  4N79 A;  1GLO A;  3IHP A;  4FIP A;  1KFX L;  2ATO A;  4DMY A;  1MEG A;  3M99 A;  1HUC B;  3D6S A;  4CDE B;  3H6S A;  3CBJ A;  5K16 A;  1GCB A;  3BOW A;  1CS8 A;  3H8C A;  4YYW A;  4PP2 E;  2DCC A;  2BDZ A;  1CQD A;  2NQG A;  1M6D A;  1F29 A;  2E03 A;  1MHW A;  3WXG A;  4CZW A;  2R9M A;  2G8E A;  2Y6E A;  3CH3 X;  2AVW A;  1PXV A;  2ACT A;  1AEC A;  3P5U A;  1NL6 A;  1NB3 A;  3N3K A;  1QXP A;  2AUX A;  3KWZ A;  5CHT A;  1BGO A;  2ARY A;  4YVA A;  3F75 A;  2FQ9 A;  3P5V A;  1PPD A;  2H7J A; 
#chains in the Genus database with same CATH topology
 3PNR A;  3CH2 X;  1PPN A;  1DKI A;  2AYN A;  4N4Z A;  1U9Q X;  4QRV A;  4X6H A;  2IBI A;  2R9F A;  4Q8H A;  1NQC A;  3HHI A;  5J94 A;  3MTN A;  1DF0 A;  5FPW A;  3OQC A;  4GUA A;  1F2A A;  1Q6K A;  1U9V A;  3DF0 A;  4MM3 B;  1YZB A;  1KHQ A;  2E01 A;  4MZO A;  2DOS A;  2P86 A;  4D8I A;  2FRQ A;  3QJ3 A;  1NLJ A;  1F2C A;  1S4V A;  2R9N A;  2B1N A;  1CPJ A;  4YYQ A;  4YV8 A;  2UZJ A;  3N3G A;  2NQA A;  3MJ5 A;  4BSQ A;  2DZY A;  3CBK A;  3PRM A;  4QRG A;  1UKF A;  2XU5 A;  3PW3 A;  3PSE A;  3IV2 A;  1PCI A;  2DZZ A;  1QDQ A;  3IMA A;  2Y5B A;  9PAP A;  2PNS A;  4ZTB A;  2O6X A;  2NQI A;  1AU2 A;  3C9E A;  4A5U A;  2E00 A;  1SNK A;  3F5V A;  2F1G A;  3PT2 A;  2DCD A;  3BPM A;  3LXS A;  1A6R A;  2R9C A;  4D8B A;  3K8U A;  4MSX A;  4I07 A;  3OVZ A;  2HXZ A;  1X9Y A;  2J7Q C;  3RNV A;  1QMY A;  3QT4 A;  3RVW A;  1PAD A;  3MOR A;  2OUL A;  5CVN B;  3HWN A;  4CDF B;  4BS6 A;  4ZUX U;  2JTC A;  3HD3 A;  3PDF A;  3V6C A;  3K24 A;  4XR7 A;  1U9W A;  4Q8G A;  4PI3 A;  4N8W A;  4WUR A;  3U8E A;  1AYV A;  1ITO A;  5PAD A;  1EWL A;  4P6G A;  3W31 A;  1XKG A;  5JA7 A;  4YYU A;  1PBH A;  3I3T A;  4RF1 A;  1STF E;  4I04 A;  6PAD A;  1EWM A;  2R6N A;  1JQP A;  3S3Q A;  8PCH A;  1YK8 A;  1Y08 A;  2VHS A;  1AU0 A;  3PHX A;  2DCB A;  4HXD B;  3RVV A;  1AYW A;  4QH6 A;  1DEU A;  4X6J A;  4W5B A;  4OW0 A;  4BQV A;  4BOQ A;  1MS6 A;  2GHU A;  3IUT A;  2P7U A;  2DCA A;  4YYS A;  1TU6 A;  2YJ9 A;  1YVB A;  2P0R A;  1KHP A;  1GEC E;  2R9O A;  2DJG B;  5CHV A;  4FJC A;  1U9X A;  3I06 A;  1CVZ A;  1AYU A;  1AIM A;  1CB5 A;  3ERV A;  4IP3 A;  1F2B A;  4MI7 A;  5JZE A;  4AXM A;  4OVZ B;  1PPO A;  5EF4 A;  2BTW B;  4MZS A;  3MHS A;  4BOZ A;  1U5I A;  5F02 A;  2AGA A;  4W4U A;  4X6I A;  1CSB B;  2FYE A;  4PT5 A;  1ATK A;  2YJB A;  1ZIV A;  2FTD A;  4M0W A;  4QBB A;  2VHF A;  2F7D A;  2JRI A;  3O1G A;  4HWY A;  4IUM A;  1EF7 A;  1NPZ A;  3GCB A;  5EGW A;  3PBH A;  4DMX A;  2YJC A;  4XUI A;  2XU1 A;  1POP A;  1Y4H A;  3BWK A;  2XU3 A;  4OEM A;  2OZ2 A;  3N4C A;  3KFQ A;  1YT7 A;  1PE6 A;  3PRP A;  1THE A;  1CTE A;  4OVZ A;  2C0Y A;  2DC7 A;  3WXF A;  2JQG R;  4YYR A;  2BTW A;  4P16 A;  4BOU A;  4CDD B;  2PAD A;  3H89 A;  1MIR A;  1TLO A;  2G6D A;  4BOP A;  5A24 A;  3PHW A;  3KKU A;  4QRX A;  4WA6 A;  1MEM A;  2CB5 A;  2FUD A;  3TRK A;  1ZCM A;  5CVM A;  3HHA A;  5JH3 A;  3PHU A;  1AU4 A;  2BU3 A;  2AS8 A;  2XU4 A;  1FH0 A;  2G7Y A;  1EWO A;  3H8B A;  5EZQ A;  3BPF A;  3KSE A;  4RY2 A;  1QOL A;  4P6E A;  2Z84 A;  3MP2 A;  2BDL A;  3KWB X;  3BBA A;  3K9M A;  2E02 A;  3QSD A;  4W5C A;  4FK5 A;  5E6J A;  1NB5 A;  3IEJ A;  3W30 A;  1PPP A;  5EZS A;  1PIP A;  2G8J A;  1KXR A;  4KLB A;  4I05 A;  2HD5 A;  1VJV A;  2DC8 A;  4G54 A;  3AI8 A;  3BCN A;  3KX1 A;  3USV A;  2DC6 A;  2AIM A;  3B21 A;  1TL9 A;  3OVX A;  2FO5 A;  1SP4 B;  1BY8 A;  3OF9 A;  4BPV A;  2B1M A;  1KFU L;  7PCK A;  2OP3 A;  1GMY A;  1ME4 A;  2NQD B;  1MDW A;  3P5X A;  2AUZ A;  2HH5 A;  3OF8 A;  4D8E A;  4R3D A;  1CV8 A;  3TNX A;  2GFO A;  1IWD A;  2J7Q A;  3LFY A;  3BB7 A;  2FT2 A;  4YYV A;  2DJF B;  4AXL A;  2YJ8 A;  1YAL A;  2AU1 A;  3E1Z B;  1YK7 A;  4CDC B;  3NHE A;  1VSN A;  3BC3 A;  2HHN A;  2PBH A;  1ME3 A;  3V6E A;  4OEL A;  1EWP A;  1AU3 A;  1K3B B;  1PVJ A;  1BQI A;  3MHH A;  1O0E A;  2JQF R;  3MTV A;  3B79 A;  5CVO B;  1ICF A;  1CJL A;  4XZX A;  3IFU A;  3KW9 A;  4BS5 A;  3P5W A;  3ZUA A;  2WBF X;  2YJ2 A;  3WXE A;  5KO3 A;  4PAD A;  4K7C A;  3S3R A;  3E9S A;  3ZNH A;  3IOQ A;  1BP4 A;  2DC9 A;  2PRE A;  2IPP B;  3RVX A;  2AYO A;  3H7D A;  2CIO A;  3OIS A;  3O0U A;  2FRA A;  4PP1 A;  4N79 A;  1GLO A;  3IHP A;  4RKX A;  4FIP A;  1KFX L;  3C0R A;  2ATO A;  4DMY A;  1MEG A;  3M99 A;  1HUC B;  3D6S A;  4CDE B;  3H6S A;  3CBJ A;  5K16 A;  1GCB A;  3BOW A;  1CS8 A;  3H8C A;  4YYW A;  4RF0 A;  4PP2 E;  2DCC A;  4BOS A;  2BDZ A;  1CQD A;  2NQG A;  1M6D A;  1F29 A;  2E03 A;  1MHW A;  3WXG A;  4CZW A;  2R9M A;  3BY4 A;  2G8E A;  2Y6E A;  3CH3 X;  3TMP A;  2AVW A;  4REZ A;  1PXV A;  2ACT A;  1AEC A;  3P5U A;  3O65 A;  1NL6 A;  1NB3 A;  3N3K A;  1QXP A;  2AUX A;  3KWZ A;  5CHT A;  1BGO A;  2ARY A;  4YVA A;  3F75 A;  2FQ9 A;  4RNA A;  2HWK A;  3P5V A;  1PPD A;  2H7J A;  2FE8 A; 
#chains in the Genus database with same CATH homology
 3PNR A;  3CH2 X;  1PPN A;  2AYN A;  4N4Z A;  1U9Q X;  4QRV A;  4X6H A;  2IBI A;  2R9F A;  4Q8H A;  1NQC A;  3HHI A;  5J94 A;  3MTN A;  1DF0 A;  5FPW A;  1F2A A;  1Q6K A;  1U9V A;  3DF0 A;  1KHQ A;  2E01 A;  4MZO A;  2P86 A;  2FRQ A;  3QJ3 A;  1NLJ A;  1F2C A;  1S4V A;  2R9N A;  2B1N A;  1CPJ A;  4YYQ A;  4YV8 A;  3N3G A;  2NQA A;  4BSQ A;  2DZY A;  3CBK A;  4QRG A;  2XU5 A;  3PW3 A;  3IV2 A;  1PCI A;  2DZZ A;  1QDQ A;  3IMA A;  2Y5B A;  4GUZ A;  9PAP A;  2PNS A;  2O6X A;  2NQI A;  1AU2 A;  2BSZ A;  3C9E A;  2E00 A;  1SNK A;  3F5V A;  2F1G A;  2DCD A;  3BPM A;  3LXS A;  1A6R A;  2R9C A;  4NV7 A;  1W6F A;  3K8U A;  4MSX A;  4I07 A;  3OVZ A;  2HXZ A;  1X9Y A;  1QMY A;  3QT4 A;  3RVW A;  1PAD A;  3MOR A;  2OUL A;  5CVN B;  3HWN A;  4CDF B;  4BS6 A;  4ZUX U;  3HD3 A;  3PDF A;  3V6C A;  3K24 A;  4XR7 A;  1U9W A;  4Q8G A;  4PI3 A;  4N8W A;  3U8E A;  1AYV A;  1ITO A;  5PAD A;  1EWL A;  4P6G A;  1XKG A;  5JA7 A;  4YYU A;  1PBH A;  3I3T A;  4BGF A;  1STF E;  4I04 A;  6PAD A;  1EWM A;  2R6N A;  1JQP A;  3S3Q A;  8PCH A;  1YK8 A;  1Y08 A;  2VHS A;  1AU0 A;  2DCB A;  3RVV A;  1AYW A;  4QH6 A;  1DEU A;  4X6J A;  4W5B A;  4BQV A;  4C5P A;  1MS6 A;  2GHU A;  2VFC A;  3IUT A;  2P7U A;  2DCA A;  4YYS A;  1TU6 A;  2YJ9 A;  1YVB A;  2P0R A;  1KHP A;  1GEC E;  2R9O A;  2DJG B;  5CHV A;  4FJC A;  1U9X A;  3I06 A;  1CVZ A;  1AYU A;  1AIM A;  1CB5 A;  3ERV A;  1F2B A;  4AXM A;  1PPO A;  5EF4 A;  1W5R A;  4MZS A;  3MHS A;  1U5I A;  5F02 A;  4W4U A;  4X6I A;  1CSB B;  2FYE A;  1ATK A;  2YJB A;  1ZIV A;  2FTD A;  4QBB A;  2VHF A;  2F7D A;  4HWY A;  3O1G A;  5EGW A;  1EF7 A;  1NPZ A;  3GCB A;  3PBH A;  4DMX A;  2YJC A;  3D9W A;  4XUI A;  2XU1 A;  1POP A;  4B55 A;  1Y4H A;  3BWK A;  2XU3 A;  4OEM A;  2OZ2 A;  3N4C A;  3KFQ A;  1YT7 A;  1PE6 A;  1THE A;  1CTE A;  2C0Y A;  2DC7 A;  3WXF A;  2JQG R;  4YYR A;  4CDD B;  2PAD A;  3H89 A;  1MIR A;  1TLO A;  2G6D A;  5A24 A;  3KKU A;  4QRX A;  4WA6 A;  1MEM A;  1GX3 A;  2CB5 A;  2FUD A;  1ZCM A;  5CVM A;  3HHA A;  5JH3 A;  1AU4 A;  2AS8 A;  2XU4 A;  1FH0 A;  2G7Y A;  1EWO A;  3H8B A;  3BPF A;  3KSE A;  4RY2 A;  1QOL A;  4P6E A;  2BDL A;  3KWB X;  3K9M A;  2E02 A;  3QSD A;  4W5C A;  4FK5 A;  1NB5 A;  3IEJ A;  1PPP A;  1PIP A;  2G8J A;  1KXR A;  4KLB A;  4I05 A;  2HD5 A;  1VJV A;  2DC8 A;  4G54 A;  3AI8 A;  3BCN A;  3KX1 A;  3USV A;  2DC6 A;  2AIM A;  1TL9 A;  3OVX A;  2FO5 A;  1SP4 B;  1BY8 A;  3OF9 A;  4BPV A;  2B1M A;  1KFU L;  4NV8 A;  7PCK A;  2OP3 A;  1GMY A;  1ME4 A;  2NQD B;  1MDW A;  3LTW A;  3P5X A;  2AUZ A;  2HH5 A;  3OF8 A;  1CV8 A;  3TNX A;  2GFO A;  1IWD A;  3LFY A;  2FT2 A;  4YYV A;  2DJF B;  4AXL A;  2YJ8 A;  1YAL A;  2AU1 A;  3E1Z B;  1YK7 A;  4CDC B;  3NHE A;  1VSN A;  3BC3 A;  2HHN A;  2PBH A;  1ME3 A;  3V6E A;  4OEL A;  1EWP A;  1AU3 A;  1K3B B;  1BQI A;  3MHH A;  1O0E A;  2JQF R;  3B79 A;  5CVO B;  1ICF A;  1CJL A;  3KW9 A;  4BS5 A;  3P5W A;  3ZUA A;  2WBF X;  2YJ2 A;  3WXE A;  4PAD A;  4K7C A;  3S3R A;  3IOQ A;  1BP4 A;  2DC9 A;  2PRE A;  2IPP B;  3RVX A;  2VFB A;  2AYO A;  3H7D A;  2CIO A;  3OIS A;  3O0U A;  2FRA A;  4PP1 A;  4N79 A;  1GLO A;  3IHP A;  4FIP A;  1KFX L;  2ATO A;  4DMY A;  1MEG A;  3M99 A;  1HUC B;  3D6S A;  4CDE B;  3H6S A;  3CBJ A;  5K16 A;  1GCB A;  3BOW A;  1CS8 A;  3H8C A;  4YYW A;  4PP2 E;  2DCC A;  2BDZ A;  1CQD A;  2NQG A;  1M6D A;  1W4T A;  1F29 A;  2E03 A;  1MHW A;  3WXG A;  4CZW A;  2R9M A;  2G8E A;  2Y6E A;  3CH3 X;  2AVW A;  1PXV A;  2ACT A;  1AEC A;  3P5U A;  1NL6 A;  1NB3 A;  1E2T A;  3N3K A;  1QXP A;  2AUX A;  3KWZ A;  5CHT A;  1BGO A;  2ARY A;  4YVA A;  3F75 A;  2FQ9 A;  3P5V A;  1PPD A;  2H7J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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