1TLOA

High resolution crystal structure of calpain i protease core in complex with e64
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
322
structure length
322
Chain Sequence
NAIKYLGQDYENLRARCLQNGVLFQDDAFPPVSHSLGFKELGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNETILHRVVPYGQSFQEGYAGIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHSAQGNEFWSALLEKAYAKVNGSYEALSGGCTSEAFEDFTGGVTEWYDLQKAPSDLYQIILKALERGSLLGCSINISDIRDLEAITFKNLVRGHAYSVTDAKQVTYQGQRVNLIRMRNPWGEVEWKGPWSDNSYEWNKVDPYEREQLRVKMEDGEFWMSFRDFIREFTKLEICNLT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures of Calpain-E64 and -Leupeptin Inhibitor Complexes Reveal Mobile Loops Gating the Active Site
pubmed doi rcsb
source organism Rattus norvegicus
molecule tags Hydrolase
molecule keywords Calpain 1, large [catalytic] subunit
total genus 95
structure length 322
sequence length 322
ec nomenclature ec 3.4.22.52: Calpain-1.
pdb deposition date 2004-06-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00648 Peptidase_C2 Calpain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1tloA02
2DZZA 1ME3A 4MSXA 2G8JA 3I06A 2VHFA 3HD3A 7PCKA 4W5CA 3P5XA 3TNXA 1Y4HA 2E02A 2P86A 1VJVA 3QT4A 1CVZA 2NQIA 3KFQA 4FJCA 4P6EA 3HWNA 4QRXA 1KHQA 3OF9A 1KFUL 3BPFA 1ITOA 2YJCA 5K16A 1QXPA 2DC6A 2R9FA 1QDQA 1NB5A 1PPDA 3QJ3A 2XU1A 1NL6A 1F29A 1CSBB 1CQDA 2FYEA 1BGOA 3BOWA 2FTDA 4FIPA 1GCBA 2VHSA 1EWLA 4PADA 1QMYA 3KKUA 1KFXL 1AYWA 1Q6KA 1U9WA 1AIMA 2B1NA 3HHAA 3O0UA 1HUCB 3IMAA 2FRQA 3IV2A 4KLBA 4X6JA 4X6IA 5J94A 1YK7A 1F2AA 9PAPA 4BS6A 3P5WA 1EF7A 3KX1A 4QRVA 3RVWA 2BDZA 3ZUAA 4PP2E 4MZSA 1QOLA 3WXFA 1DEUA 2R9CA 2PADA 2OP3A 4K7CA 4OEMA 1SP4B 2F1GA 2CB5A 1AECA 2E00A 3C9EA 2GFOA 1MS6A 3B79A 1ZCMA 3OISA 1XKGA 3CH2X 3LXSA 2DZYA 4YYSA 2YJ9A 2GHUA 2HHNA 4OELA 1O0EA 1NLJA 3IHPA 4YYQA 1MHWA 5CHVA 3GCBA 3V6CA 4BS5A 2IBIA 1M6DA 1TLOA 1PADA 2AYOA 2DCCA 3MHHA 4X6HA 3H89A 3I3TA 3E1ZB 2G8EA 2AUZA 4PP1A 2XU4A 1MDWA 2G7YA 4AXLA 5CHTA 3MORA 1GLOA 1K3BB 3RVXA 1U9QX 1PCIA 3N4CA 2YJ8A 1NPZA 4CDEB 1BY8A 2Y5BA 4WA6A 1ICFA 5F02A 1Y08A 2P7UA 4YYWA 1PXVA 1F2CA 4HWYA 2DJGB 3KWBX 1YK8A 4W4UA 3BCNA 2AS8A 2HXZA 2FQ9A 2Y6EA 2H7JA 1POPA 3CH3X 3BWKA 1NB3A 3BC3A 3S3QA 3CBJA 2PNSA 4PI3A 1AYUA 2DC8A 2WBFX 3IOQA 2YJ2A 3QSDA 1PPOA 3IEJA 3P5VA 2HH5A 3N3GA 1A6RA 3OF8A 2XU5A 2E01A 3OVXA 3P5UA 1TU6A 3IUTA 4MZOA 2JQGR 2FO5A 4CZWA 1IWDA 1BP4A 1CV8A 5CVNB 4CDDB 3OVZA 5CVOB 3WXGA 3H8CA 2ATOA 1AU3A 3KSEA 1EWMA 2FT2A 3S3RA 1MIRA 1ZIVA 4DMXA 1U5IA 2PBHA 1GMYA 1ME4A 3H8BA 4QH6A 3V6EA 4Q8GA 1AU2A 2OZ2A 4RY2A 2G6DA 3WXEA 3N3KA 5EF4A 3D6SA 2R9OA 4XUIA 1S4VA 1VSNA 2AU1A 2JQFR 3K8UA 3HHIA 2XU3A 5EGWA 2FUDA 3KW9A 5FPWA 2YJBA 3F5VA 3DF0A 1YALA 2DC9A 1THEA 4N79A 4Q8HA 3ERVA 2DCBA 2NQDB 4CDFB 3MHSA 3PW3A 2PREA 4CDCB 4YYVA 4YYUA 1KHPA 1X9YA 3AI8A 3PNRA 3H6SA 3K9MA 4P6GA 4N4ZA 2DCAA 1CJLA 1YT7A 1U9VA 1PIPA 4I07A 5A24A 3PDFA 1YVBA 2ACTA 2B1MA 1U9XA 2IPPB 4G54A 1AU0A 4YVAA 3PBHA 3U8EA 5JH3A 1JQPA 2E03A 2AUXA 3O1GA 3H7DA 1CB5A 1PPNA 4FK5A 4I04A 2FRAA 2R9NA 3BPMA 1STFE 1GECE 2AIMA 6PADA 1PBHA 3LFYA 2O6XA 4AXMA 2AVWA 1EWPA 4QBBA 5PADA 4BPVA 3NHEA 1KXRA 2DCDA 3RVVA 1ATKA 3F75A 4ZUXU 3CBKA 3KWZA 2BDLA 2F7DA 1NQCA 3MTNA 4QRGA 8PCHA 2CIOA 2C0YA 1CS8A 2DC7A 1PE6A 4I05A 1F2BA 2AYNA 1AYVA 2NQAA 1EWOA 4BQVA 3USVA 1CTEA 1DF0A 2R6NA 1TL9A 2DJFB 2OULA 3M99A 4W5BA 1AU4A 4YV8A 4N8WA 2NQGA 1FH0A 1BQIA 4DMYA 2HD5A 5CVMA 2R9MA 2P0RA 1MEGA 4YYRA 1PPPA 1CPJA 4XR7A 5JA7A 1MEMA 1SNKA 2ARYA 3K24A 4BSQA
chains in the Genus database with same CATH superfamily
2DZZA 1ME3A 4MSXA 2G8JA 3I06A 2VHFA 4RF1A 4A5UA 5EZSA 3HD3A 1PVJA 7PCKA 4W5CA 3P5XA 3TNXA 1Y4HA 2E02A 2P86A 1VJVA 3QT4A 1CVZA 2NQIA 3KFQA 4FJCA 4P6EA 3HWNA 4QRXA 1KHQA 3OF9A 1KFUL 3BPFA 4GUAA 1ITOA 2YJCA 5K16A 1QXPA 2DC6A 2JRIA 2R9FA 1QDQA 1NB5A 1PPDA 2JTCA 3QJ3A 2XU1A 1NL6A 1F29A 1CSBB 1CQDA 2FYEA 1BGOA 3BOWA 2FTDA 4FIPA 1GCBA 2FE8A 2VHSA 1EWLA 4PADA 4IUMA 3B21A 1QMYA 3KKUA 4BOSA 1KFXL 1AYWA 1Q6KA 1U9WA 1AIMA 2B1NA 3HHAA 3O0UA 1HUCB 3IMAA 2FRQA 3IV2A 4KLBA 4X6JA 4X6IA 5J94A 1YK7A 1F2AA 9PAPA 4BS6A 3P5WA 1EF7A 2J7QC 3KX1A 4QRVA 4OW0A 3RVWA 2BDZA 3ZUAA 4PP2E 4MZSA 1QOLA 3WXFA 1DEUA 2R9CA 2PADA 2OP3A 4K7CA 5JZEA 4OEMA 3PHUA 1SP4B 2F1GA 2CB5A 1AECA 2E00A 3C9EA 2GFOA 3W31A 1MS6A 3B79A 1ZCMA 3OISA 4WURA 1XKGA 3CH2X 3LXSA 2BTWB 2DZYA 4YYSA 2YJ9A 2GHUA 2HHNA 4OELA 1O0EA 1NLJA 3BY4A 3IHPA 4YYQA 1MHWA 2J7QA 5CHVA 3GCBA 3V6CA 4BS5A 2IBIA 4MI7A 1M6DA 1TLOA 1PADA 2AYOA 2DOSA 3OQCA 2DCCA 3MHHA 4X6HA 3H89A 3I3TA 3E1ZB 2G8EA 2AUZA 3BB7A 4PP1A 2UZJA 2XU4A 1MDWA 2G7YA 4AXLA 5CHTA 3MORA 2HWKA 1GLOA 1K3BB 3RVXA 1U9QX 4BOQA 1PCIA 4RKXA 3N4CA 3PSEA 2YJ8A 1NPZA 4CDEB 1BY8A 2Y5BA 3MJ5A 4WA6A 1ICFA 5F02A 1Y08A 2P7UA 4YYWA 1PXVA 1F2CA 4HWYA 2DJGB 3TRKA 3KWBX 1YK8A 4OVZB 4W4UA 3BCNA 2AS8A 2HXZA 2FQ9A 3PRPA 2Y6EA 2H7JA 1POPA 3RNVA 3CH3X 3BWKA 1NB3A 3BC3A 3S3QA 3CBJA 2PNSA 4PI3A 4OVZA 4MM3B 1AYUA 2DC8A 2WBFX 3IOQA 2YJ2A 3QSDA 1PPOA 3IEJA 3P5VA 2HH5A 3N3GA 1A6RA 3OF8A 2XU5A 2BTWA 2E01A 3OVXA 3P5UA 1TU6A 3IUTA 5E6JA 4MZOA 2JQGR 2FO5A 4CZWA 1IWDA 4BOUA 1BP4A 1CV8A 5CVNB 4CDDB 3OVZA 5CVOB 3WXGA 3H8CA 5EZQA 2ATOA 3C0RA 1AU3A 3KSEA 1EWMA 2FT2A 3S3RA 1MIRA 1ZIVA 3W30A 4DMXA 1U5IA 5KO3A 2PBHA 4BOZA 1DKIA 1GMYA 1ME4A 3H8BA 4QH6A 3V6EA 4Q8GA 1AU2A 2OZ2A 4RY2A 2G6DA 3WXEA 3ZNHA 3N3KA 5EF4A 4D8BA 3D6SA 2R9OA 4XUIA 1S4VA 1VSNA 2AU1A 2JQFR 3PRMA 3K8UA 3HHIA 2XU3A 5EGWA 2FUDA 2BU3A 1UKFA 3KW9A 5FPWA 4RF0A 2YJBA 3F5VA 3DF0A 2Z84A 1YALA 3TMPA 2DC9A 4BOPA 1THEA 4N79A 4Q8HA 3ERVA 2DCBA 2NQDB 4CDFB 3MHSA 3PW3A 2PREA 4CDCB 4YYVA 4YYUA 1KHPA 1X9YA 2AGAA 3AI8A 4ZTBA 3PNRA 3H6SA 3K9MA 4P6GA 4N4ZA 2DCAA 1CJLA 1YT7A 1U9VA 1PIPA 4I07A 5A24A 3PDFA 1YVBA 2ACTA 2B1MA 1U9XA 2IPPB 4G54A 1AU0A 4YVAA 3PBHA 3U8EA 5JH3A 1JQPA 2E03A 2AUXA 3O1GA 3H7DA 3IFUA 4REZA 1CB5A 1PPNA 3PHWA 4FK5A 4I04A 2FRAA 2R9NA 3BPMA 1STFE 1GECE 2AIMA 6PADA 1PBHA 3LFYA 2O6XA 4AXMA 2AVWA 1EWPA 3PT2A 4QBBA 4R3DA 5PADA 4BPVA 3NHEA 1KXRA 2DCDA 3RVVA 1ATKA 3F75A 4ZUXU 3MP2A 3CBKA 3KWZA 2BDLA 3MTVA 2F7DA 4HXDB 1NQCA 3MTNA 4QRGA 3PHXA 4RNAA 4D8EA 8PCHA 2CIOA 2C0YA 1CS8A 2DC7A 1PE6A 4I05A 1F2BA 2AYNA 1AYVA 2NQAA 1EWOA 3O65A 4BQVA 3USVA 1CTEA 1DF0A 2R6NA 1TL9A 2DJFB 2OULA 3M99A 1YZBA 3BBAA 4W5BA 1AU4A 4YV8A 4N8WA 2NQGA 1FH0A 1BQIA 4DMYA 2HD5A 4PT5A 5CVMA 2R9MA 2P0RA 1MEGA 4D8IA 4M0WA 4P16A 4YYRA 3E9SA 4IP3A 1PPPA 1CPJA 4XR7A 5JA7A 4XZXA 1MEMA 1SNKA 2ARYA 3K24A 4BSQA
chains in the Genus database with same CATH topology
2DZZA 1ME3A 4MSXA 2G8JA 3I06A 2VHFA 3HD3A 4C5PA 7PCKA 4W5CA 3P5XA 3TNXA 1Y4HA 2E02A 2P86A 1VJVA 3QT4A 1CVZA 2NQIA 3KFQA 4FJCA 4P6EA 3HWNA 4QRXA 1KHQA 3OF9A 1KFUL 3BPFA 1ITOA 4NV8A 2YJCA 5K16A 1E2TA 1QXPA 2DC6A 2R9FA 1QDQA 1NB5A 1PPDA 3QJ3A 2XU1A 1NL6A 1F29A 1CSBB 1CQDA 2FYEA 1BGOA 3BOWA 2FTDA 4FIPA 1GCBA 2VHSA 1EWLA 4PADA 1QMYA 3KKUA 1KFXL 1AYWA 1Q6KA 1U9WA 1AIMA 2B1NA 3HHAA 3O0UA 1HUCB 4BGFA 3IMAA 2FRQA 3IV2A 4KLBA 4GUZA 4X6JA 4B55A 4X6IA 5J94A 1YK7A 1F2AA 9PAPA 4BS6A 3P5WA 1EF7A 3KX1A 4QRVA 3RVWA 2BDZA 3ZUAA 4PP2E 4MZSA 1GX3A 1QOLA 3WXFA 1DEUA 2R9CA 2PADA 2OP3A 4K7CA 4OEMA 1SP4B 2F1GA 2CB5A 1AECA 2E00A 3C9EA 2GFOA 1MS6A 3B79A 1ZCMA 3OISA 1XKGA 3CH2X 3LXSA 2DZYA 4YYSA 2YJ9A 2GHUA 2HHNA 4OELA 1O0EA 1NLJA 3IHPA 4YYQA 1MHWA 5CHVA 3GCBA 3V6CA 4BS5A 2IBIA 1M6DA 1TLOA 1PADA 2AYOA 2DCCA 3MHHA 4X6HA 3H89A 3I3TA 3E1ZB 2G8EA 2AUZA 4PP1A 2XU4A 1MDWA 2G7YA 4AXLA 5CHTA 3MORA 1GLOA 1K3BB 3RVXA 1U9QX 1PCIA 3N4CA 2YJ8A 1NPZA 4CDEB 1BY8A 2Y5BA 4WA6A 1ICFA 5F02A 1Y08A 2P7UA 2VFCA 4YYWA 1PXVA 1F2CA 4HWYA 2DJGB 3KWBX 1YK8A 4W4UA 3BCNA 2AS8A 2HXZA 2FQ9A 2Y6EA 2H7JA 3LTWA 1POPA 3CH3X 3BWKA 1NB3A 3BC3A 3S3QA 3CBJA 2PNSA 4PI3A 1AYUA 2DC8A 2WBFX 3IOQA 2YJ2A 3QSDA 1PPOA 3IEJA 3P5VA 2HH5A 3N3GA 1A6RA 3OF8A 2XU5A 2BSZA 2E01A 3OVXA 3P5UA 1TU6A 3IUTA 4MZOA 2JQGR 2FO5A 4CZWA 1IWDA 1BP4A 1CV8A 5CVNB 4CDDB 3OVZA 5CVOB 3WXGA 3H8CA 2ATOA 1AU3A 3KSEA 1EWMA 2FT2A 3S3RA 1MIRA 1ZIVA 4DMXA 1U5IA 2PBHA 1GMYA 1ME4A 3H8BA 4QH6A 3V6EA 4Q8GA 1AU2A 2OZ2A 4RY2A 2G6DA 3WXEA 3N3KA 5EF4A 3D6SA 2R9OA 4XUIA 1S4VA 1VSNA 2AU1A 2JQFR 3K8UA 3HHIA 2XU3A 5EGWA 2FUDA 3KW9A 5FPWA 2YJBA 3F5VA 3DF0A 1YALA 2DC9A 1THEA 4N79A 4Q8HA 3ERVA 2DCBA 2NQDB 4CDFB 3MHSA 3PW3A 2PREA 4CDCB 4YYVA 4YYUA 1KHPA 1X9YA 3AI8A 3PNRA 3H6SA 3K9MA 4P6GA 4N4ZA 2DCAA 1CJLA 1YT7A 1U9VA 1PIPA 4I07A 5A24A 3PDFA 1YVBA 2ACTA 2B1MA 1U9XA 2IPPB 4G54A 1AU0A 4YVAA 3PBHA 3U8EA 5JH3A 1JQPA 1W5RA 2E03A 2AUXA 3O1GA 1W6FA 3H7DA 1CB5A 1PPNA 4NV7A 4FK5A 4I04A 2FRAA 2R9NA 3BPMA 1STFE 1GECE 2AIMA 6PADA 1PBHA 3LFYA 2O6XA 4AXMA 2AVWA 1EWPA 4QBBA 5PADA 4BPVA 3NHEA 1KXRA 3D9WA 2DCDA 3RVVA 1ATKA 3F75A 4ZUXU 3CBKA 3KWZA 2BDLA 2F7DA 1NQCA 3MTNA 4QRGA 8PCHA 2CIOA 2C0YA 1CS8A 2DC7A 1PE6A 4I05A 1F2BA 2AYNA 1AYVA 2NQAA 1EWOA 2VFBA 4BQVA 3USVA 1CTEA 1DF0A 2R6NA 1TL9A 2DJFB 2OULA 3M99A 4W5BA 1AU4A 4YV8A 4N8WA 2NQGA 1FH0A 1W4TA 1BQIA 4DMYA 2HD5A 5CVMA 2R9MA 2P0RA 1MEGA 4YYRA 1PPPA 1CPJA 4XR7A 5JA7A 1MEMA 1SNKA 2ARYA 3K24A 4BSQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DZZ A;  1ME3 A;  4MSX A;  2G8J A;  3I06 A;  2VHF A;  3HD3 A;  7PCK A;  4W5C A;  3P5X A;  3TNX A;  1Y4H A;  2E02 A;  2P86 A;  1VJV A;  3QT4 A;  1CVZ A;  2NQI A;  3KFQ A;  4FJC A;  4P6E A;  3HWN A;  4QRX A;  1KHQ A;  3OF9 A;  1KFU L;  3BPF A;  1ITO A;  2YJC A;  5K16 A;  1QXP A;  2DC6 A;  2R9F A;  1QDQ A;  1NB5 A;  1PPD A;  3QJ3 A;  2XU1 A;  1NL6 A;  1F29 A;  1CSB B;  1CQD A;  2FYE A;  1BGO A;  3BOW A;  2FTD A;  4FIP A;  1GCB A;  2VHS A;  1EWL A;  4PAD A;  1QMY A;  3KKU A;  1KFX L;  1AYW A;  1Q6K A;  1U9W A;  1AIM A;  2B1N A;  3HHA A;  3O0U A;  1HUC B;  3IMA A;  2FRQ A;  3IV2 A;  4KLB A;  4X6J A;  4X6I A;  5J94 A;  1YK7 A;  1F2A A;  9PAP A;  4BS6 A;  3P5W A;  1EF7 A;  3KX1 A;  4QRV A;  3RVW A;  2BDZ A;  3ZUA A;  4PP2 E;  4MZS A;  1QOL A;  3WXF A;  1DEU A;  2R9C A;  2PAD A;  2OP3 A;  4K7C A;  4OEM A;  1SP4 B;  2F1G A;  2CB5 A;  1AEC A;  2E00 A;  3C9E A;  2GFO A;  1MS6 A;  3B79 A;  1ZCM A;  3OIS A;  1XKG A;  3CH2 X;  3LXS A;  2DZY A;  4YYS A;  2YJ9 A;  2GHU A;  2HHN A;  4OEL A;  1O0E A;  1NLJ A;  3IHP A;  4YYQ A;  1MHW A;  5CHV A;  3GCB A;  3V6C A;  4BS5 A;  2IBI A;  1M6D A;  1TLO A;  1PAD A;  2AYO A;  2DCC A;  3MHH A;  4X6H A;  3H89 A;  3I3T A;  3E1Z B;  2G8E A;  2AUZ A;  4PP1 A;  2XU4 A;  1MDW A;  2G7Y A;  4AXL A;  5CHT A;  3MOR A;  1GLO A;  1K3B B;  3RVX A;  1U9Q X;  1PCI A;  3N4C A;  2YJ8 A;  1NPZ A;  4CDE B;  1BY8 A;  2Y5B A;  4WA6 A;  1ICF A;  5F02 A;  1Y08 A;  2P7U A;  4YYW A;  1PXV A;  1F2C A;  4HWY A;  2DJG B;  3KWB X;  1YK8 A;  4W4U A;  3BCN A;  2AS8 A;  2HXZ A;  2FQ9 A;  2Y6E A;  2H7J A;  1POP A;  3CH3 X;  3BWK A;  1NB3 A;  3BC3 A;  3S3Q A;  3CBJ A;  2PNS A;  4PI3 A;  1AYU A;  2DC8 A;  2WBF X;  3IOQ A;  2YJ2 A;  3QSD A;  1PPO A;  3IEJ A;  3P5V A;  2HH5 A;  3N3G A;  1A6R A;  3OF8 A;  2XU5 A;  2E01 A;  3OVX A;  3P5U A;  1TU6 A;  3IUT A;  4MZO A;  2JQG R;  2FO5 A;  4CZW A;  1IWD A;  1BP4 A;  1CV8 A;  5CVN B;  4CDD B;  3OVZ A;  5CVO B;  3WXG A;  3H8C A;  2ATO A;  1AU3 A;  3KSE A;  1EWM A;  2FT2 A;  3S3R A;  1MIR A;  1ZIV A;  4DMX A;  1U5I A;  2PBH A;  1GMY A;  1ME4 A;  3H8B A;  4QH6 A;  3V6E A;  4Q8G A;  1AU2 A;  2OZ2 A;  4RY2 A;  2G6D A;  3WXE A;  3N3K A;  5EF4 A;  3D6S A;  2R9O A;  4XUI A;  1S4V A;  1VSN A;  2AU1 A;  2JQF R;  3K8U A;  3HHI A;  2XU3 A;  5EGW A;  2FUD A;  3KW9 A;  5FPW A;  2YJB A;  3F5V A;  3DF0 A;  1YAL A;  2DC9 A;  1THE A;  4N79 A;  4Q8H A;  3ERV A;  2DCB A;  2NQD B;  4CDF B;  3MHS A;  3PW3 A;  2PRE A;  4CDC B;  4YYV A;  4YYU A;  1KHP A;  1X9Y A;  3AI8 A;  3PNR A;  3H6S A;  3K9M A;  4P6G A;  4N4Z A;  2DCA A;  1CJL A;  1YT7 A;  1U9V A;  1PIP A;  4I07 A;  5A24 A;  3PDF A;  1YVB A;  2ACT A;  2B1M A;  1U9X A;  2IPP B;  4G54 A;  1AU0 A;  4YVA A;  3PBH A;  3U8E A;  5JH3 A;  1JQP A;  2E03 A;  2AUX A;  3O1G A;  3H7D A;  1CB5 A;  1PPN A;  4FK5 A;  4I04 A;  2FRA A;  2R9N A;  3BPM A;  1STF E;  1GEC E;  2AIM A;  6PAD A;  1PBH A;  3LFY A;  2O6X A;  4AXM A;  2AVW A;  1EWP A;  4QBB A;  5PAD A;  4BPV A;  3NHE A;  1KXR A;  2DCD A;  3RVV A;  1ATK A;  3F75 A;  4ZUX U;  3CBK A;  3KWZ A;  2BDL A;  2F7D A;  1NQC A;  3MTN A;  4QRG A;  8PCH A;  2CIO A;  2C0Y A;  1CS8 A;  2DC7 A;  1PE6 A;  4I05 A;  1F2B A;  2AYN A;  1AYV A;  2NQA A;  1EWO A;  4BQV A;  3USV A;  1CTE A;  1DF0 A;  2R6N A;  1TL9 A;  2DJF B;  2OUL A;  3M99 A;  4W5B A;  1AU4 A;  4YV8 A;  4N8W A;  2NQG A;  1FH0 A;  1BQI A;  4DMY A;  2HD5 A;  5CVM A;  2R9M A;  2P0R A;  1MEG A;  4YYR A;  1PPP A;  1CPJ A;  4XR7 A;  5JA7 A;  1MEM A;  1SNK A;  2ARY A;  3K24 A;  4BSQ A; 
#chains in the Genus database with same CATH topology
 2DZZ A;  1ME3 A;  4MSX A;  2G8J A;  3I06 A;  2VHF A;  4RF1 A;  4A5U A;  5EZS A;  3HD3 A;  1PVJ A;  7PCK A;  4W5C A;  3P5X A;  3TNX A;  1Y4H A;  2E02 A;  2P86 A;  1VJV A;  3QT4 A;  1CVZ A;  2NQI A;  3KFQ A;  4FJC A;  4P6E A;  3HWN A;  4QRX A;  1KHQ A;  3OF9 A;  1KFU L;  3BPF A;  4GUA A;  1ITO A;  2YJC A;  5K16 A;  1QXP A;  2DC6 A;  2JRI A;  2R9F A;  1QDQ A;  1NB5 A;  1PPD A;  2JTC A;  3QJ3 A;  2XU1 A;  1NL6 A;  1F29 A;  1CSB B;  1CQD A;  2FYE A;  1BGO A;  3BOW A;  2FTD A;  4FIP A;  1GCB A;  2FE8 A;  2VHS A;  1EWL A;  4PAD A;  4IUM A;  3B21 A;  1QMY A;  3KKU A;  4BOS A;  1KFX L;  1AYW A;  1Q6K A;  1U9W A;  1AIM A;  2B1N A;  3HHA A;  3O0U A;  1HUC B;  3IMA A;  2FRQ A;  3IV2 A;  4KLB A;  4X6J A;  4X6I A;  5J94 A;  1YK7 A;  1F2A A;  9PAP A;  4BS6 A;  3P5W A;  1EF7 A;  2J7Q C;  3KX1 A;  4QRV A;  4OW0 A;  3RVW A;  2BDZ A;  3ZUA A;  4PP2 E;  4MZS A;  1QOL A;  3WXF A;  1DEU A;  2R9C A;  2PAD A;  2OP3 A;  4K7C A;  5JZE A;  4OEM A;  3PHU A;  1SP4 B;  2F1G A;  2CB5 A;  1AEC A;  2E00 A;  3C9E A;  2GFO A;  3W31 A;  1MS6 A;  3B79 A;  1ZCM A;  3OIS A;  4WUR A;  1XKG A;  3CH2 X;  3LXS A;  2BTW B;  2DZY A;  4YYS A;  2YJ9 A;  2GHU A;  2HHN A;  4OEL A;  1O0E A;  1NLJ A;  3BY4 A;  3IHP A;  4YYQ A;  1MHW A;  2J7Q A;  5CHV A;  3GCB A;  3V6C A;  4BS5 A;  2IBI A;  4MI7 A;  1M6D A;  1TLO A;  1PAD A;  2AYO A;  2DOS A;  3OQC A;  2DCC A;  3MHH A;  4X6H A;  3H89 A;  3I3T A;  3E1Z B;  2G8E A;  2AUZ A;  3BB7 A;  4PP1 A;  2UZJ A;  2XU4 A;  1MDW A;  2G7Y A;  4AXL A;  5CHT A;  3MOR A;  2HWK A;  1GLO A;  1K3B B;  3RVX A;  1U9Q X;  4BOQ A;  1PCI A;  4RKX A;  3N4C A;  3PSE A;  2YJ8 A;  1NPZ A;  4CDE B;  1BY8 A;  2Y5B A;  3MJ5 A;  4WA6 A;  1ICF A;  5F02 A;  1Y08 A;  2P7U A;  4YYW A;  1PXV A;  1F2C A;  4HWY A;  2DJG B;  3TRK A;  3KWB X;  1YK8 A;  4OVZ B;  4W4U A;  3BCN A;  2AS8 A;  2HXZ A;  2FQ9 A;  3PRP A;  2Y6E A;  2H7J A;  1POP A;  3RNV A;  3CH3 X;  3BWK A;  1NB3 A;  3BC3 A;  3S3Q A;  3CBJ A;  2PNS A;  4PI3 A;  4OVZ A;  4MM3 B;  1AYU A;  2DC8 A;  2WBF X;  3IOQ A;  2YJ2 A;  3QSD A;  1PPO A;  3IEJ A;  3P5V A;  2HH5 A;  3N3G A;  1A6R A;  3OF8 A;  2XU5 A;  2BTW A;  2E01 A;  3OVX A;  3P5U A;  1TU6 A;  3IUT A;  5E6J A;  4MZO A;  2JQG R;  2FO5 A;  4CZW A;  1IWD A;  4BOU A;  1BP4 A;  1CV8 A;  5CVN B;  4CDD B;  3OVZ A;  5CVO B;  3WXG A;  3H8C A;  5EZQ A;  2ATO A;  3C0R A;  1AU3 A;  3KSE A;  1EWM A;  2FT2 A;  3S3R A;  1MIR A;  1ZIV A;  3W30 A;  4DMX A;  1U5I A;  5KO3 A;  2PBH A;  4BOZ A;  1DKI A;  1GMY A;  1ME4 A;  3H8B A;  4QH6 A;  3V6E A;  4Q8G A;  1AU2 A;  2OZ2 A;  4RY2 A;  2G6D A;  3WXE A;  3ZNH A;  3N3K A;  5EF4 A;  4D8B A;  3D6S A;  2R9O A;  4XUI A;  1S4V A;  1VSN A;  2AU1 A;  2JQF R;  3PRM A;  3K8U A;  3HHI A;  2XU3 A;  5EGW A;  2FUD A;  2BU3 A;  1UKF A;  3KW9 A;  5FPW A;  4RF0 A;  2YJB A;  3F5V A;  3DF0 A;  2Z84 A;  1YAL A;  3TMP A;  2DC9 A;  4BOP A;  1THE A;  4N79 A;  4Q8H A;  3ERV A;  2DCB A;  2NQD B;  4CDF B;  3MHS A;  3PW3 A;  2PRE A;  4CDC B;  4YYV A;  4YYU A;  1KHP A;  1X9Y A;  2AGA A;  3AI8 A;  4ZTB A;  3PNR A;  3H6S A;  3K9M A;  4P6G A;  4N4Z A;  2DCA A;  1CJL A;  1YT7 A;  1U9V A;  1PIP A;  4I07 A;  5A24 A;  3PDF A;  1YVB A;  2ACT A;  2B1M A;  1U9X A;  2IPP B;  4G54 A;  1AU0 A;  4YVA A;  3PBH A;  3U8E A;  5JH3 A;  1JQP A;  2E03 A;  2AUX A;  3O1G A;  3H7D A;  3IFU A;  4REZ A;  1CB5 A;  1PPN A;  3PHW A;  4FK5 A;  4I04 A;  2FRA A;  2R9N A;  3BPM A;  1STF E;  1GEC E;  2AIM A;  6PAD A;  1PBH A;  3LFY A;  2O6X A;  4AXM A;  2AVW A;  1EWP A;  3PT2 A;  4QBB A;  4R3D A;  5PAD A;  4BPV A;  3NHE A;  1KXR A;  2DCD A;  3RVV A;  1ATK A;  3F75 A;  4ZUX U;  3MP2 A;  3CBK A;  3KWZ A;  2BDL A;  3MTV A;  2F7D A;  4HXD B;  1NQC A;  3MTN A;  4QRG A;  3PHX A;  4RNA A;  4D8E A;  8PCH A;  2CIO A;  2C0Y A;  1CS8 A;  2DC7 A;  1PE6 A;  4I05 A;  1F2B A;  2AYN A;  1AYV A;  2NQA A;  1EWO A;  3O65 A;  4BQV A;  3USV A;  1CTE A;  1DF0 A;  2R6N A;  1TL9 A;  2DJF B;  2OUL A;  3M99 A;  1YZB A;  3BBA A;  4W5B A;  1AU4 A;  4YV8 A;  4N8W A;  2NQG A;  1FH0 A;  1BQI A;  4DMY A;  2HD5 A;  4PT5 A;  5CVM A;  2R9M A;  2P0R A;  1MEG A;  4D8I A;  4M0W A;  4P16 A;  4YYR A;  3E9S A;  4IP3 A;  1PPP A;  1CPJ A;  4XR7 A;  5JA7 A;  4XZX A;  1MEM A;  1SNK A;  2ARY A;  3K24 A;  4BSQ A; 
#chains in the Genus database with same CATH homology
 2DZZ A;  1ME3 A;  4MSX A;  2G8J A;  3I06 A;  2VHF A;  3HD3 A;  4C5P A;  7PCK A;  4W5C A;  3P5X A;  3TNX A;  1Y4H A;  2E02 A;  2P86 A;  1VJV A;  3QT4 A;  1CVZ A;  2NQI A;  3KFQ A;  4FJC A;  4P6E A;  3HWN A;  4QRX A;  1KHQ A;  3OF9 A;  1KFU L;  3BPF A;  1ITO A;  4NV8 A;  2YJC A;  5K16 A;  1E2T A;  1QXP A;  2DC6 A;  2R9F A;  1QDQ A;  1NB5 A;  1PPD A;  3QJ3 A;  2XU1 A;  1NL6 A;  1F29 A;  1CSB B;  1CQD A;  2FYE A;  1BGO A;  3BOW A;  2FTD A;  4FIP A;  1GCB A;  2VHS A;  1EWL A;  4PAD A;  1QMY A;  3KKU A;  1KFX L;  1AYW A;  1Q6K A;  1U9W A;  1AIM A;  2B1N A;  3HHA A;  3O0U A;  1HUC B;  4BGF A;  3IMA A;  2FRQ A;  3IV2 A;  4KLB A;  4GUZ A;  4X6J A;  4B55 A;  4X6I A;  5J94 A;  1YK7 A;  1F2A A;  9PAP A;  4BS6 A;  3P5W A;  1EF7 A;  3KX1 A;  4QRV A;  3RVW A;  2BDZ A;  3ZUA A;  4PP2 E;  4MZS A;  1GX3 A;  1QOL A;  3WXF A;  1DEU A;  2R9C A;  2PAD A;  2OP3 A;  4K7C A;  4OEM A;  1SP4 B;  2F1G A;  2CB5 A;  1AEC A;  2E00 A;  3C9E A;  2GFO A;  1MS6 A;  3B79 A;  1ZCM A;  3OIS A;  1XKG A;  3CH2 X;  3LXS A;  2DZY A;  4YYS A;  2YJ9 A;  2GHU A;  2HHN A;  4OEL A;  1O0E A;  1NLJ A;  3IHP A;  4YYQ A;  1MHW A;  5CHV A;  3GCB A;  3V6C A;  4BS5 A;  2IBI A;  1M6D A;  1TLO A;  1PAD A;  2AYO A;  2DCC A;  3MHH A;  4X6H A;  3H89 A;  3I3T A;  3E1Z B;  2G8E A;  2AUZ A;  4PP1 A;  2XU4 A;  1MDW A;  2G7Y A;  4AXL A;  5CHT A;  3MOR A;  1GLO A;  1K3B B;  3RVX A;  1U9Q X;  1PCI A;  3N4C A;  2YJ8 A;  1NPZ A;  4CDE B;  1BY8 A;  2Y5B A;  4WA6 A;  1ICF A;  5F02 A;  1Y08 A;  2P7U A;  2VFC A;  4YYW A;  1PXV A;  1F2C A;  4HWY A;  2DJG B;  3KWB X;  1YK8 A;  4W4U A;  3BCN A;  2AS8 A;  2HXZ A;  2FQ9 A;  2Y6E A;  2H7J A;  3LTW A;  1POP A;  3CH3 X;  3BWK A;  1NB3 A;  3BC3 A;  3S3Q A;  3CBJ A;  2PNS A;  4PI3 A;  1AYU A;  2DC8 A;  2WBF X;  3IOQ A;  2YJ2 A;  3QSD A;  1PPO A;  3IEJ A;  3P5V A;  2HH5 A;  3N3G A;  1A6R A;  3OF8 A;  2XU5 A;  2BSZ A;  2E01 A;  3OVX A;  3P5U A;  1TU6 A;  3IUT A;  4MZO A;  2JQG R;  2FO5 A;  4CZW A;  1IWD A;  1BP4 A;  1CV8 A;  5CVN B;  4CDD B;  3OVZ A;  5CVO B;  3WXG A;  3H8C A;  2ATO A;  1AU3 A;  3KSE A;  1EWM A;  2FT2 A;  3S3R A;  1MIR A;  1ZIV A;  4DMX A;  1U5I A;  2PBH A;  1GMY A;  1ME4 A;  3H8B A;  4QH6 A;  3V6E A;  4Q8G A;  1AU2 A;  2OZ2 A;  4RY2 A;  2G6D A;  3WXE A;  3N3K A;  5EF4 A;  3D6S A;  2R9O A;  4XUI A;  1S4V A;  1VSN A;  2AU1 A;  2JQF R;  3K8U A;  3HHI A;  2XU3 A;  5EGW A;  2FUD A;  3KW9 A;  5FPW A;  2YJB A;  3F5V A;  3DF0 A;  1YAL A;  2DC9 A;  1THE A;  4N79 A;  4Q8H A;  3ERV A;  2DCB A;  2NQD B;  4CDF B;  3MHS A;  3PW3 A;  2PRE A;  4CDC B;  4YYV A;  4YYU A;  1KHP A;  1X9Y A;  3AI8 A;  3PNR A;  3H6S A;  3K9M A;  4P6G A;  4N4Z A;  2DCA A;  1CJL A;  1YT7 A;  1U9V A;  1PIP A;  4I07 A;  5A24 A;  3PDF A;  1YVB A;  2ACT A;  2B1M A;  1U9X A;  2IPP B;  4G54 A;  1AU0 A;  4YVA A;  3PBH A;  3U8E A;  5JH3 A;  1JQP A;  1W5R A;  2E03 A;  2AUX A;  3O1G A;  1W6F A;  3H7D A;  1CB5 A;  1PPN A;  4NV7 A;  4FK5 A;  4I04 A;  2FRA A;  2R9N A;  3BPM A;  1STF E;  1GEC E;  2AIM A;  6PAD A;  1PBH A;  3LFY A;  2O6X A;  4AXM A;  2AVW A;  1EWP A;  4QBB A;  5PAD A;  4BPV A;  3NHE A;  1KXR A;  3D9W A;  2DCD A;  3RVV A;  1ATK A;  3F75 A;  4ZUX U;  3CBK A;  3KWZ A;  2BDL A;  2F7D A;  1NQC A;  3MTN A;  4QRG A;  8PCH A;  2CIO A;  2C0Y A;  1CS8 A;  2DC7 A;  1PE6 A;  4I05 A;  1F2B A;  2AYN A;  1AYV A;  2NQA A;  1EWO A;  2VFB A;  4BQV A;  3USV A;  1CTE A;  1DF0 A;  2R6N A;  1TL9 A;  2DJF B;  2OUL A;  3M99 A;  4W5B A;  1AU4 A;  4YV8 A;  4N8W A;  2NQG A;  1FH0 A;  1W4T A;  1BQI A;  4DMY A;  2HD5 A;  5CVM A;  2R9M A;  2P0R A;  1MEG A;  4YYR A;  1PPP A;  1CPJ A;  4XR7 A;  5JA7 A;  1MEM A;  1SNK A;  2ARY A;  3K24 A;  4BSQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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