2XU5A

Cathepsin l with a nitrile inhibitor
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
220
structure length
216
Chain Sequence
APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFEDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Systematic Investigation of Halogen Bonding in Protein-Ligand Interactions.
pubmed doi rcsb
molecule keywords CATHEPSIN L1
molecule tags Hydrolase
source organism Homo sapiens
total genus 67
structure length 216
sequence length 220
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2010-10-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2xu5A00
3F5VA 9PAPA 1DEUA 3BWKA 3OVXA 2GFOA 3HWNA 3C9EA 3O1GA 4XR7A 4CDEB 2OZ2A 3KWBX 1O0EA 2E02A 1YVBA 3KX1A 5FPWA 1U9VA 1PPNA 5EGWA 3IOQA 3OVZA 2AS8A 5J94A 1THEA 2IBIA 2DC6A 3HHIA 4I07A 3MORA 4FK5A 2FUDA 4RY2A 2YJ8A 3N3GA 1CB5A 4QRGA 3MHSA 2AYOA 1Y4HA 1BY8A 3PDFA 6PADA 2DCAA 2PBHA 2VHFA 2P0RA 1DF0A 3M99A 2BDZA 1KFXL 1SP4B 3BCNA 4N79A 5PADA 1CQDA 3HD3A 3TNXA 4G54A 2AIMA 2ATOA 4ZUXU 1SNKA 1MIRA 3K8UA 4X6IA 1EWOA 2FYEA 1GLOA 2NQIA 1U9QX 1ZCMA 3ERVA 2G7YA 2XU1A 2Y6EA 1ITOA 1ICFA 1PCIA 4WA6A 3PNRA 1NLJA 1U5IA 2C0YA 3B79A 4OEMA 2FQ9A 1VSNA 2E03A 2FTDA 1MEGA 3OF8A 1ATKA 4CDFB 4KLBA 4I05A 3GCBA 1PBHA 1QDQA 1XKGA 1ME3A 2B1MA 3V6EA 3OISA 3H8CA 2AYNA 4W5BA 3KFQA 5CVMA 3CBKA 1NQCA 4DMXA 4Q8HA 1AYWA 1U9XA 2YJCA 3PBHA 1CTEA 2DJGB 2DZZA 3IUTA 2PREA 1YK8A 4P6GA 3N4CA 5CVOB 2NQGA 4N4ZA 1CVZA 1MHWA 1F2AA 4P6EA 4YV8A 3QJ3A 4YYWA 1A6RA 3S3QA 2AU1A 4CZWA 3MTNA 1POPA 2B1NA 1EF7A 3K9MA 3AI8A 3P5UA 2CB5A 1AECA 5CHVA 2DC9A 1AU4A 1AYUA 3LFYA 2YJ2A 2G6DA 3P5VA 3U8EA 1CJLA 1NB3A 4YYRA 8PCHA 2R9FA 4YYSA 3QT4A 2ACTA 4MZSA 1QXPA 3IV2A 1Q6KA 1KHQA 2OP3A 2ARYA 2FT2A 1TU6A 4YYQA 3WXGA 1AU2A 1BGOA 2F1GA 1HUCB 3KWZA 1PPDA 2HH5A 3NHEA 4DMYA 3MHHA 3BPMA 3V6CA 3WXEA 4N8WA 4K7CA 3RVVA 4QH6A 3CH2X 4CDCB 3H8BA 3KW9A 2VHSA 2P7UA 2IPPB 4PP2E 1YK7A 2DC8A 1VJVA 2CIOA 4PADA 2XU3A 5CVNB 4QRVA 1AU3A 2Y5BA 4YYVA 4MSXA 1AU0A 4BPVA 3IMAA 2H7JA 1CS8A 1KHPA 1CV8A 3KSEA 2BDLA 2HHNA 2OULA 2F7DA 2AUZA 3PW3A 4BS5A 1GMYA 2DCDA 1QMYA 2NQAA 4Q8GA 3I3TA 1AIMA 1STFE 1BP4A 4PP1A 2JQGR 2E00A 1CPJA 5CHTA 4YVAA 4BS6A 1KXRA 1TLOA 3BOWA 2YJBA 2YJ9A 3USVA 3E1ZB 1Y08A 4W4UA 5K16A 3K24A 4BSQA 1M6DA 1YT7A 2G8EA 1S4VA 2DCCA 3OF9A 4QBBA 2WBFX 2G8JA 2R6NA 2HD5A 1NB5A 3BC3A 1EWPA 4OELA 5A24A 2XU5A 3P5XA 3H89A 1F2CA 3O0UA 1PPPA 3P5WA 2AVWA 1X9YA 1PIPA 4MZOA 1F2BA 1YALA 3N3KA 2NQDB 1IWDA 4AXLA 1F29A 1TL9A 1MEMA 3QSDA 4QRXA 1PADA 2DCBA 5JA7A 3H6SA 1JQPA 1NPZA 2HXZA 3WXFA 3CH3X 3KKUA 1PXVA 3D6SA 2AUXA 3IHPA 4FIPA 4BQVA 1ME4A 1PE6A 2O6XA 5EF4A 1FH0A 2FO5A 1U9WA 2DJFB 4XUIA 1MDWA 2P86A 7PCKA 4HWYA 4I04A 4PI3A 2R9NA 1GCBA 3IEJA 1QOLA 4X6JA 1BQIA 2R9OA 4W5CA 1EWLA 4AXMA 1PPOA 1NL6A 2R9CA 3I06A 3ZUAA 4YYUA 5F02A 1CSBB 4CDDB 2FRAA 3CBJA 2GHUA 3RVWA 3S3RA 2PNSA 2DC7A 1KFUL 3F75A 3RVXA 2JQFR 3LXSA 4X6HA 1AYVA 1MS6A 1ZIVA 2PADA 1K3BB 3HHAA 2E01A 2R9MA 1GECE 3DF0A 2XU4A 3H7DA 5JH3A 3BPFA 4FJCA 2DZYA 1EWMA 2FRQA
chains in the Genus database with same CATH superfamily
3F5VA 9PAPA 1DEUA 4OVZB 3BWKA 3OVXA 2GFOA 3HWNA 1UKFA 3C9EA 3RNVA 3O1GA 4XR7A 4CDEB 2OZ2A 3KWBX 1O0EA 2E02A 1YVBA 3PHUA 3KX1A 5FPWA 1U9VA 1PPNA 5EGWA 3IOQA 3OVZA 2AS8A 5J94A 1THEA 2IBIA 2DC6A 4D8BA 3HHIA 4I07A 3MORA 4FK5A 2FUDA 3BY4A 4RY2A 2YJ8A 3N3GA 1CB5A 4QRGA 3MHSA 2AYOA 1Y4HA 1BY8A 3PDFA 6PADA 4RF0A 2DCAA 2PBHA 3MP2A 2VHFA 2P0RA 4M0WA 1DF0A 3M99A 2BDZA 1KFXL 1SP4B 3BCNA 4N79A 5PADA 1CQDA 3E9SA 3HD3A 3TNXA 4G54A 2AIMA 2ATOA 4ZUXU 1SNKA 3C0RA 1MIRA 3K8UA 4X6IA 1EWOA 2FYEA 1GLOA 2NQIA 1U9QX 3O65A 1ZCMA 3ERVA 2G7YA 2XU1A 4BOQA 2Y6EA 1ITOA 1ICFA 1PCIA 4WA6A 3PNRA 1NLJA 1U5IA 2C0YA 3B79A 4OEMA 4RKXA 2FQ9A 1VSNA 2E03A 2FTDA 4RF1A 1MEGA 3OF8A 1ATKA 4CDFB 1PVJA 4KLBA 4WURA 4I05A 3W30A 4GUAA 3GCBA 1PBHA 1QDQA 1XKGA 1ME3A 2B1MA 3V6EA 3OISA 4XZXA 3H8CA 2AYNA 4W5BA 3KFQA 5CVMA 3CBKA 1NQCA 4DMXA 4Q8HA 3B21A 1AYWA 1U9XA 2YJCA 3PBHA 1CTEA 5E6JA 2DJGB 2DZZA 3IUTA 2PREA 1YK8A 4P6GA 3N4CA 5CVOB 2NQGA 4N4ZA 1CVZA 1MHWA 1F2AA 4P6EA 4YV8A 3QJ3A 4YYWA 3TMPA 1A6RA 3S3QA 2AU1A 4CZWA 3MTNA 3PHXA 1POPA 2B1NA 4D8EA 2BU3A 1EF7A 2UZJA 3K9MA 3AI8A 3P5UA 2CB5A 1AECA 5CHVA 2DC9A 1AU4A 1AYUA 3LFYA 2YJ2A 2G6DA 3P5VA 4ZTBA 3U8EA 1CJLA 1NB3A 4MI7A 4YYRA 2R9FA 8PCHA 4YYSA 3QT4A 2HWKA 3BBAA 2ACTA 4MZSA 1QXPA 3IV2A 1Q6KA 1KHQA 2OP3A 2ARYA 5EZSA 2FT2A 1TU6A 4YYQA 3WXGA 1AU2A 4D8IA 1BGOA 2F1GA 1HUCB 3KWZA 1PPDA 4OW0A 4BOZA 3MTVA 2HH5A 3NHEA 4DMYA 3MHHA 3BPMA 3V6CA 5JZEA 3WXEA 4N8WA 4K7CA 3RVVA 4QH6A 3CH2X 4CDCB 4IUMA 3H8BA 3KW9A 2VHSA 2P7UA 2IPPB 4PP2E 2J7QA 3ZNHA 1YK7A 2DC8A 4BOUA 1VJVA 2CIOA 4REZA 4PADA 2XU3A 5CVNB 4MM3B 4QRVA 1AU3A 2Y5BA 4YYVA 4MSXA 1AU0A 4BPVA 3IMAA 2H7JA 1CS8A 1KHPA 1CV8A 2Z84A 2JRIA 3KSEA 2BDLA 2HHNA 2OULA 3PRPA 5KO3A 2F7DA 2AUZA 3PW3A 4BS5A 4PT5A 1GMYA 2DCDA 1QMYA 2NQAA 4P16A 4Q8GA 3I3TA 1AIMA 3OQCA 1STFE 1BP4A 4PP1A 3TRKA 2JQGR 4BOSA 2E00A 1CPJA 3PRMA 5CHTA 4YVAA 4BS6A 1KXRA 1TLOA 3BOWA 2YJBA 2YJ9A 3BB7A 3USVA 3E1ZB 1Y08A 4W4UA 5K16A 3K24A 4BSQA 1M6DA 1YT7A 4IP3A 2G8EA 1YZBA 1S4VA 2DCCA 3OF9A 4QBBA 2WBFX 2FE8A 2G8JA 3W31A 2R6NA 2HD5A 1NB5A 3BC3A 1EWPA 4OELA 5A24A 2XU5A 3P5XA 3H89A 1F2CA 4BOPA 3O0UA 1PPPA 3P5WA 2BTWA 2AVWA 1X9YA 1PIPA 4MZOA 1F2BA 1YALA 3N3KA 2NQDB 1IWDA 4AXLA 1F29A 1TL9A 1MEMA 3QSDA 4QRXA 1PADA 4OVZA 2DCBA 5JA7A 3H6SA 3PHWA 1JQPA 1NPZA 2HXZA 3IFUA 5EZQA 3WXFA 3CH3X 3KKUA 1PXVA 3D6SA 2AUXA 3IHPA 4FIPA 4BQVA 2AGAA 1ME4A 1PE6A 2O6XA 5EF4A 1FH0A 2FO5A 2JTCA 1U9WA 2DJFB 4XUIA 1MDWA 2P86A 7PCKA 3MJ5A 4HWYA 4I04A 4PI3A 2R9NA 1GCBA 3IEJA 1QOLA 4X6JA 1BQIA 2R9OA 4W5CA 1EWLA 4AXMA 1PPOA 1NL6A 2R9CA 4RNAA 3I06A 3ZUAA 4YYUA 4R3DA 5F02A 1CSBB 4CDDB 2J7QC 2FRAA 3CBJA 2GHUA 3RVWA 3S3RA 2PNSA 2DC7A 1KFUL 3F75A 3RVXA 3PT2A 2JQFR 3LXSA 4X6HA 2BTWB 1AYVA 1MS6A 1ZIVA 2PADA 1DKIA 1K3BB 3HHAA 2E01A 2R9MA 1GECE 3DF0A 2XU4A 3H7DA 5JH3A 3BPFA 4FJCA 2DZYA 3PSEA 1EWMA 4HXDB 4A5UA 2DOSA 2FRQA
chains in the Genus database with same CATH topology
3F5VA 9PAPA 1DEUA 3BWKA 3OVXA 2GFOA 3HWNA 3C9EA 3O1GA 4XR7A 4CDEB 2OZ2A 3KWBX 1O0EA 2E02A 1YVBA 3KX1A 5FPWA 1U9VA 1PPNA 5EGWA 3IOQA 3OVZA 2AS8A 5J94A 1THEA 2IBIA 2DC6A 3HHIA 4I07A 3MORA 4FK5A 2FUDA 4RY2A 2YJ8A 3N3GA 1CB5A 4QRGA 3MHSA 2AYOA 1Y4HA 1BY8A 3PDFA 6PADA 2DCAA 2PBHA 1E2TA 3LTWA 2VHFA 2P0RA 1DF0A 3M99A 2BSZA 2BDZA 1KFXL 1SP4B 3BCNA 4N79A 5PADA 1CQDA 3HD3A 3TNXA 4G54A 2AIMA 2ATOA 4ZUXU 1SNKA 1MIRA 3K8UA 4X6IA 1EWOA 2FYEA 1GLOA 2NQIA 1U9QX 4NV7A 1ZCMA 3ERVA 2G7YA 2XU1A 2Y6EA 1ITOA 1ICFA 1PCIA 4WA6A 3PNRA 1NLJA 1U5IA 2C0YA 3B79A 4OEMA 2FQ9A 1VSNA 2E03A 2FTDA 1MEGA 3OF8A 1ATKA 4CDFB 4KLBA 1W4TA 4I05A 3GCBA 1PBHA 1QDQA 1XKGA 1ME3A 2B1MA 3V6EA 3OISA 3H8CA 2AYNA 4W5BA 3KFQA 5CVMA 3CBKA 1NQCA 4DMXA 4Q8HA 1AYWA 1U9XA 2YJCA 3PBHA 2VFBA 1CTEA 2DJGB 2DZZA 3IUTA 2PREA 1YK8A 4P6GA 3N4CA 5CVOB 2NQGA 4N4ZA 1CVZA 1W6FA 1MHWA 1F2AA 4P6EA 4YV8A 3QJ3A 4YYWA 1A6RA 3S3QA 2AU1A 4CZWA 3MTNA 1POPA 2B1NA 1EF7A 3K9MA 3AI8A 3P5UA 2CB5A 1AECA 5CHVA 2DC9A 1AU4A 1AYUA 3LFYA 2YJ2A 2G6DA 3P5VA 3U8EA 1GX3A 1CJLA 1NB3A 4YYRA 8PCHA 2R9FA 4YYSA 3QT4A 2ACTA 4MZSA 1QXPA 3IV2A 1Q6KA 1KHQA 2OP3A 2ARYA 2FT2A 1TU6A 4YYQA 3WXGA 1AU2A 1BGOA 2F1GA 1HUCB 3KWZA 1PPDA 2HH5A 3NHEA 4DMYA 3MHHA 3BPMA 3V6CA 3WXEA 4N8WA 1W5RA 4K7CA 3RVVA 4QH6A 3CH2X 4CDCB 3H8BA 3KW9A 4C5PA 2VHSA 2P7UA 2IPPB 4PP2E 1YK7A 2DC8A 1VJVA 4BGFA 2CIOA 4PADA 2XU3A 5CVNB 4QRVA 1AU3A 2Y5BA 4YYVA 4MSXA 1AU0A 4BPVA 3IMAA 2H7JA 1CS8A 1KHPA 1CV8A 3KSEA 2BDLA 2HHNA 2OULA 2F7DA 2AUZA 3PW3A 4BS5A 4GUZA 1GMYA 2DCDA 1QMYA 2NQAA 4Q8GA 3I3TA 1AIMA 1STFE 1BP4A 4PP1A 2JQGR 2E00A 1CPJA 5CHTA 4YVAA 4BS6A 1KXRA 1TLOA 3BOWA 2YJBA 2YJ9A 3USVA 3E1ZB 1Y08A 4W4UA 5K16A 3K24A 4BSQA 1M6DA 1YT7A 2G8EA 1S4VA 2DCCA 3OF9A 4QBBA 2WBFX 2G8JA 2R6NA 2HD5A 1NB5A 3BC3A 1EWPA 4OELA 5A24A 2XU5A 3P5XA 3H89A 1F2CA 3O0UA 1PPPA 3P5WA 2AVWA 1X9YA 1PIPA 4MZOA 1F2BA 2VFCA 1YALA 3N3KA 2NQDB 1IWDA 4AXLA 1F29A 1TL9A 1MEMA 3QSDA 4QRXA 1PADA 2DCBA 5JA7A 3H6SA 1JQPA 1NPZA 2HXZA 3WXFA 3CH3X 3KKUA 4NV8A 1PXVA 3D6SA 2AUXA 3IHPA 4FIPA 4BQVA 1ME4A 1PE6A 2O6XA 5EF4A 1FH0A 2FO5A 1U9WA 2DJFB 4XUIA 1MDWA 2P86A 7PCKA 4HWYA 4I04A 4PI3A 2R9NA 1GCBA 3IEJA 1QOLA 4X6JA 1BQIA 2R9OA 4W5CA 1EWLA 4AXMA 1PPOA 1NL6A 2R9CA 3D9WA 3I06A 3ZUAA 4YYUA 4B55A 5F02A 1CSBB 4CDDB 2FRAA 3CBJA 2GHUA 3RVWA 3S3RA 2PNSA 2DC7A 1KFUL 3F75A 3RVXA 2JQFR 3LXSA 4X6HA 1AYVA 1MS6A 1ZIVA 2PADA 1K3BB 3HHAA 2E01A 2R9MA 1GECE 3DF0A 2XU4A 3H7DA 5JH3A 3BPFA 4FJCA 2DZYA 1EWMA 2FRQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3F5V A;  9PAP A;  1DEU A;  3BWK A;  3OVX A;  2GFO A;  3HWN A;  3C9E A;  3O1G A;  4XR7 A;  4CDE B;  2OZ2 A;  3KWB X;  1O0E A;  2E02 A;  1YVB A;  3KX1 A;  5FPW A;  1U9V A;  1PPN A;  5EGW A;  3IOQ A;  3OVZ A;  2AS8 A;  5J94 A;  1THE A;  2IBI A;  2DC6 A;  3HHI A;  4I07 A;  3MOR A;  4FK5 A;  2FUD A;  4RY2 A;  2YJ8 A;  3N3G A;  1CB5 A;  4QRG A;  3MHS A;  2AYO A;  1Y4H A;  1BY8 A;  3PDF A;  6PAD A;  2DCA A;  2PBH A;  2VHF A;  2P0R A;  1DF0 A;  3M99 A;  2BDZ A;  1KFX L;  1SP4 B;  3BCN A;  4N79 A;  5PAD A;  1CQD A;  3HD3 A;  3TNX A;  4G54 A;  2AIM A;  2ATO A;  4ZUX U;  1SNK A;  1MIR A;  3K8U A;  4X6I A;  1EWO A;  2FYE A;  1GLO A;  2NQI A;  1U9Q X;  1ZCM A;  3ERV A;  2G7Y A;  2XU1 A;  2Y6E A;  1ITO A;  1ICF A;  1PCI A;  4WA6 A;  3PNR A;  1NLJ A;  1U5I A;  2C0Y A;  3B79 A;  4OEM A;  2FQ9 A;  1VSN A;  2E03 A;  2FTD A;  1MEG A;  3OF8 A;  1ATK A;  4CDF B;  4KLB A;  4I05 A;  3GCB A;  1PBH A;  1QDQ A;  1XKG A;  1ME3 A;  2B1M A;  3V6E A;  3OIS A;  3H8C A;  2AYN A;  4W5B A;  3KFQ A;  5CVM A;  3CBK A;  1NQC A;  4DMX A;  4Q8H A;  1AYW A;  1U9X A;  2YJC A;  3PBH A;  1CTE A;  2DJG B;  2DZZ A;  3IUT A;  2PRE A;  1YK8 A;  4P6G A;  3N4C A;  5CVO B;  2NQG A;  4N4Z A;  1CVZ A;  1MHW A;  1F2A A;  4P6E A;  4YV8 A;  3QJ3 A;  4YYW A;  1A6R A;  3S3Q A;  2AU1 A;  4CZW A;  3MTN A;  1POP A;  2B1N A;  1EF7 A;  3K9M A;  3AI8 A;  3P5U A;  2CB5 A;  1AEC A;  5CHV A;  2DC9 A;  1AU4 A;  1AYU A;  3LFY A;  2YJ2 A;  2G6D A;  3P5V A;  3U8E A;  1CJL A;  1NB3 A;  4YYR A;  8PCH A;  2R9F A;  4YYS A;  3QT4 A;  2ACT A;  4MZS A;  1QXP A;  3IV2 A;  1Q6K A;  1KHQ A;  2OP3 A;  2ARY A;  2FT2 A;  1TU6 A;  4YYQ A;  3WXG A;  1AU2 A;  1BGO A;  2F1G A;  1HUC B;  3KWZ A;  1PPD A;  2HH5 A;  3NHE A;  4DMY A;  3MHH A;  3BPM A;  3V6C A;  3WXE A;  4N8W A;  4K7C A;  3RVV A;  4QH6 A;  3CH2 X;  4CDC B;  3H8B A;  3KW9 A;  2VHS A;  2P7U A;  2IPP B;  4PP2 E;  1YK7 A;  2DC8 A;  1VJV A;  2CIO A;  4PAD A;  2XU3 A;  5CVN B;  4QRV A;  1AU3 A;  2Y5B A;  4YYV A;  4MSX A;  1AU0 A;  4BPV A;  3IMA A;  2H7J A;  1CS8 A;  1KHP A;  1CV8 A;  3KSE A;  2BDL A;  2HHN A;  2OUL A;  2F7D A;  2AUZ A;  3PW3 A;  4BS5 A;  1GMY A;  2DCD A;  1QMY A;  2NQA A;  4Q8G A;  3I3T A;  1AIM A;  1STF E;  1BP4 A;  4PP1 A;  2JQG R;  2E00 A;  1CPJ A;  5CHT A;  4YVA A;  4BS6 A;  1KXR A;  1TLO A;  3BOW A;  2YJB A;  2YJ9 A;  3USV A;  3E1Z B;  1Y08 A;  4W4U A;  5K16 A;  3K24 A;  4BSQ A;  1M6D A;  1YT7 A;  2G8E A;  1S4V A;  2DCC A;  3OF9 A;  4QBB A;  2WBF X;  2G8J A;  2R6N A;  2HD5 A;  1NB5 A;  3BC3 A;  1EWP A;  4OEL A;  5A24 A;  2XU5 A;  3P5X A;  3H89 A;  1F2C A;  3O0U A;  1PPP A;  3P5W A;  2AVW A;  1X9Y A;  1PIP A;  4MZO A;  1F2B A;  1YAL A;  3N3K A;  2NQD B;  1IWD A;  4AXL A;  1F29 A;  1TL9 A;  1MEM A;  3QSD A;  4QRX A;  1PAD A;  2DCB A;  5JA7 A;  3H6S A;  1JQP A;  1NPZ A;  2HXZ A;  3WXF A;  3CH3 X;  3KKU A;  1PXV A;  3D6S A;  2AUX A;  3IHP A;  4FIP A;  4BQV A;  1ME4 A;  1PE6 A;  2O6X A;  5EF4 A;  1FH0 A;  2FO5 A;  1U9W A;  2DJF B;  4XUI A;  1MDW A;  2P86 A;  7PCK A;  4HWY A;  4I04 A;  4PI3 A;  2R9N A;  1GCB A;  3IEJ A;  1QOL A;  4X6J A;  1BQI A;  2R9O A;  4W5C A;  1EWL A;  4AXM A;  1PPO A;  1NL6 A;  2R9C A;  3I06 A;  3ZUA A;  4YYU A;  5F02 A;  1CSB B;  4CDD B;  2FRA A;  3CBJ A;  2GHU A;  3RVW A;  3S3R A;  2PNS A;  2DC7 A;  1KFU L;  3F75 A;  3RVX A;  2JQF R;  3LXS A;  4X6H A;  1AYV A;  1MS6 A;  1ZIV A;  2PAD A;  1K3B B;  3HHA A;  2E01 A;  2R9M A;  1GEC E;  3DF0 A;  2XU4 A;  3H7D A;  5JH3 A;  3BPF A;  4FJC A;  2DZY A;  1EWM A;  2FRQ A; 
#chains in the Genus database with same CATH topology
 3F5V A;  9PAP A;  1DEU A;  4OVZ B;  3BWK A;  3OVX A;  2GFO A;  3HWN A;  1UKF A;  3C9E A;  3RNV A;  3O1G A;  4XR7 A;  4CDE B;  2OZ2 A;  3KWB X;  1O0E A;  2E02 A;  1YVB A;  3PHU A;  3KX1 A;  5FPW A;  1U9V A;  1PPN A;  5EGW A;  3IOQ A;  3OVZ A;  2AS8 A;  5J94 A;  1THE A;  2IBI A;  2DC6 A;  4D8B A;  3HHI A;  4I07 A;  3MOR A;  4FK5 A;  2FUD A;  3BY4 A;  4RY2 A;  2YJ8 A;  3N3G A;  1CB5 A;  4QRG A;  3MHS A;  2AYO A;  1Y4H A;  1BY8 A;  3PDF A;  6PAD A;  4RF0 A;  2DCA A;  2PBH A;  3MP2 A;  2VHF A;  2P0R A;  4M0W A;  1DF0 A;  3M99 A;  2BDZ A;  1KFX L;  1SP4 B;  3BCN A;  4N79 A;  5PAD A;  1CQD A;  3E9S A;  3HD3 A;  3TNX A;  4G54 A;  2AIM A;  2ATO A;  4ZUX U;  1SNK A;  3C0R A;  1MIR A;  3K8U A;  4X6I A;  1EWO A;  2FYE A;  1GLO A;  2NQI A;  1U9Q X;  3O65 A;  1ZCM A;  3ERV A;  2G7Y A;  2XU1 A;  4BOQ A;  2Y6E A;  1ITO A;  1ICF A;  1PCI A;  4WA6 A;  3PNR A;  1NLJ A;  1U5I A;  2C0Y A;  3B79 A;  4OEM A;  4RKX A;  2FQ9 A;  1VSN A;  2E03 A;  2FTD A;  4RF1 A;  1MEG A;  3OF8 A;  1ATK A;  4CDF B;  1PVJ A;  4KLB A;  4WUR A;  4I05 A;  3W30 A;  4GUA A;  3GCB A;  1PBH A;  1QDQ A;  1XKG A;  1ME3 A;  2B1M A;  3V6E A;  3OIS A;  4XZX A;  3H8C A;  2AYN A;  4W5B A;  3KFQ A;  5CVM A;  3CBK A;  1NQC A;  4DMX A;  4Q8H A;  3B21 A;  1AYW A;  1U9X A;  2YJC A;  3PBH A;  1CTE A;  5E6J A;  2DJG B;  2DZZ A;  3IUT A;  2PRE A;  1YK8 A;  4P6G A;  3N4C A;  5CVO B;  2NQG A;  4N4Z A;  1CVZ A;  1MHW A;  1F2A A;  4P6E A;  4YV8 A;  3QJ3 A;  4YYW A;  3TMP A;  1A6R A;  3S3Q A;  2AU1 A;  4CZW A;  3MTN A;  3PHX A;  1POP A;  2B1N A;  4D8E A;  2BU3 A;  1EF7 A;  2UZJ A;  3K9M A;  3AI8 A;  3P5U A;  2CB5 A;  1AEC A;  5CHV A;  2DC9 A;  1AU4 A;  1AYU A;  3LFY A;  2YJ2 A;  2G6D A;  3P5V A;  4ZTB A;  3U8E A;  1CJL A;  1NB3 A;  4MI7 A;  4YYR A;  2R9F A;  8PCH A;  4YYS A;  3QT4 A;  2HWK A;  3BBA A;  2ACT A;  4MZS A;  1QXP A;  3IV2 A;  1Q6K A;  1KHQ A;  2OP3 A;  2ARY A;  5EZS A;  2FT2 A;  1TU6 A;  4YYQ A;  3WXG A;  1AU2 A;  4D8I A;  1BGO A;  2F1G A;  1HUC B;  3KWZ A;  1PPD A;  4OW0 A;  4BOZ A;  3MTV A;  2HH5 A;  3NHE A;  4DMY A;  3MHH A;  3BPM A;  3V6C A;  5JZE A;  3WXE A;  4N8W A;  4K7C A;  3RVV A;  4QH6 A;  3CH2 X;  4CDC B;  4IUM A;  3H8B A;  3KW9 A;  2VHS A;  2P7U A;  2IPP B;  4PP2 E;  2J7Q A;  3ZNH A;  1YK7 A;  2DC8 A;  4BOU A;  1VJV A;  2CIO A;  4REZ A;  4PAD A;  2XU3 A;  5CVN B;  4MM3 B;  4QRV A;  1AU3 A;  2Y5B A;  4YYV A;  4MSX A;  1AU0 A;  4BPV A;  3IMA A;  2H7J A;  1CS8 A;  1KHP A;  1CV8 A;  2Z84 A;  2JRI A;  3KSE A;  2BDL A;  2HHN A;  2OUL A;  3PRP A;  5KO3 A;  2F7D A;  2AUZ A;  3PW3 A;  4BS5 A;  4PT5 A;  1GMY A;  2DCD A;  1QMY A;  2NQA A;  4P16 A;  4Q8G A;  3I3T A;  1AIM A;  3OQC A;  1STF E;  1BP4 A;  4PP1 A;  3TRK A;  2JQG R;  4BOS A;  2E00 A;  1CPJ A;  3PRM A;  5CHT A;  4YVA A;  4BS6 A;  1KXR A;  1TLO A;  3BOW A;  2YJB A;  2YJ9 A;  3BB7 A;  3USV A;  3E1Z B;  1Y08 A;  4W4U A;  5K16 A;  3K24 A;  4BSQ A;  1M6D A;  1YT7 A;  4IP3 A;  2G8E A;  1YZB A;  1S4V A;  2DCC A;  3OF9 A;  4QBB A;  2WBF X;  2FE8 A;  2G8J A;  3W31 A;  2R6N A;  2HD5 A;  1NB5 A;  3BC3 A;  1EWP A;  4OEL A;  5A24 A;  2XU5 A;  3P5X A;  3H89 A;  1F2C A;  4BOP A;  3O0U A;  1PPP A;  3P5W A;  2BTW A;  2AVW A;  1X9Y A;  1PIP A;  4MZO A;  1F2B A;  1YAL A;  3N3K A;  2NQD B;  1IWD A;  4AXL A;  1F29 A;  1TL9 A;  1MEM A;  3QSD A;  4QRX A;  1PAD A;  4OVZ A;  2DCB A;  5JA7 A;  3H6S A;  3PHW A;  1JQP A;  1NPZ A;  2HXZ A;  3IFU A;  5EZQ A;  3WXF A;  3CH3 X;  3KKU A;  1PXV A;  3D6S A;  2AUX A;  3IHP A;  4FIP A;  4BQV A;  2AGA A;  1ME4 A;  1PE6 A;  2O6X A;  5EF4 A;  1FH0 A;  2FO5 A;  2JTC A;  1U9W A;  2DJF B;  4XUI A;  1MDW A;  2P86 A;  7PCK A;  3MJ5 A;  4HWY A;  4I04 A;  4PI3 A;  2R9N A;  1GCB A;  3IEJ A;  1QOL A;  4X6J A;  1BQI A;  2R9O A;  4W5C A;  1EWL A;  4AXM A;  1PPO A;  1NL6 A;  2R9C A;  4RNA A;  3I06 A;  3ZUA A;  4YYU A;  4R3D A;  5F02 A;  1CSB B;  4CDD B;  2J7Q C;  2FRA A;  3CBJ A;  2GHU A;  3RVW A;  3S3R A;  2PNS A;  2DC7 A;  1KFU L;  3F75 A;  3RVX A;  3PT2 A;  2JQF R;  3LXS A;  4X6H A;  2BTW B;  1AYV A;  1MS6 A;  1ZIV A;  2PAD A;  1DKI A;  1K3B B;  3HHA A;  2E01 A;  2R9M A;  1GEC E;  3DF0 A;  2XU4 A;  3H7D A;  5JH3 A;  3BPF A;  4FJC A;  2DZY A;  3PSE A;  1EWM A;  4HXD B;  4A5U A;  2DOS A;  2FRQ A; 
#chains in the Genus database with same CATH homology
 3F5V A;  9PAP A;  1DEU A;  3BWK A;  3OVX A;  2GFO A;  3HWN A;  3C9E A;  3O1G A;  4XR7 A;  4CDE B;  2OZ2 A;  3KWB X;  1O0E A;  2E02 A;  1YVB A;  3KX1 A;  5FPW A;  1U9V A;  1PPN A;  5EGW A;  3IOQ A;  3OVZ A;  2AS8 A;  5J94 A;  1THE A;  2IBI A;  2DC6 A;  3HHI A;  4I07 A;  3MOR A;  4FK5 A;  2FUD A;  4RY2 A;  2YJ8 A;  3N3G A;  1CB5 A;  4QRG A;  3MHS A;  2AYO A;  1Y4H A;  1BY8 A;  3PDF A;  6PAD A;  2DCA A;  2PBH A;  1E2T A;  3LTW A;  2VHF A;  2P0R A;  1DF0 A;  3M99 A;  2BSZ A;  2BDZ A;  1KFX L;  1SP4 B;  3BCN A;  4N79 A;  5PAD A;  1CQD A;  3HD3 A;  3TNX A;  4G54 A;  2AIM A;  2ATO A;  4ZUX U;  1SNK A;  1MIR A;  3K8U A;  4X6I A;  1EWO A;  2FYE A;  1GLO A;  2NQI A;  1U9Q X;  4NV7 A;  1ZCM A;  3ERV A;  2G7Y A;  2XU1 A;  2Y6E A;  1ITO A;  1ICF A;  1PCI A;  4WA6 A;  3PNR A;  1NLJ A;  1U5I A;  2C0Y A;  3B79 A;  4OEM A;  2FQ9 A;  1VSN A;  2E03 A;  2FTD A;  1MEG A;  3OF8 A;  1ATK A;  4CDF B;  4KLB A;  1W4T A;  4I05 A;  3GCB A;  1PBH A;  1QDQ A;  1XKG A;  1ME3 A;  2B1M A;  3V6E A;  3OIS A;  3H8C A;  2AYN A;  4W5B A;  3KFQ A;  5CVM A;  3CBK A;  1NQC A;  4DMX A;  4Q8H A;  1AYW A;  1U9X A;  2YJC A;  3PBH A;  2VFB A;  1CTE A;  2DJG B;  2DZZ A;  3IUT A;  2PRE A;  1YK8 A;  4P6G A;  3N4C A;  5CVO B;  2NQG A;  4N4Z A;  1CVZ A;  1W6F A;  1MHW A;  1F2A A;  4P6E A;  4YV8 A;  3QJ3 A;  4YYW A;  1A6R A;  3S3Q A;  2AU1 A;  4CZW A;  3MTN A;  1POP A;  2B1N A;  1EF7 A;  3K9M A;  3AI8 A;  3P5U A;  2CB5 A;  1AEC A;  5CHV A;  2DC9 A;  1AU4 A;  1AYU A;  3LFY A;  2YJ2 A;  2G6D A;  3P5V A;  3U8E A;  1GX3 A;  1CJL A;  1NB3 A;  4YYR A;  8PCH A;  2R9F A;  4YYS A;  3QT4 A;  2ACT A;  4MZS A;  1QXP A;  3IV2 A;  1Q6K A;  1KHQ A;  2OP3 A;  2ARY A;  2FT2 A;  1TU6 A;  4YYQ A;  3WXG A;  1AU2 A;  1BGO A;  2F1G A;  1HUC B;  3KWZ A;  1PPD A;  2HH5 A;  3NHE A;  4DMY A;  3MHH A;  3BPM A;  3V6C A;  3WXE A;  4N8W A;  1W5R A;  4K7C A;  3RVV A;  4QH6 A;  3CH2 X;  4CDC B;  3H8B A;  3KW9 A;  4C5P A;  2VHS A;  2P7U A;  2IPP B;  4PP2 E;  1YK7 A;  2DC8 A;  1VJV A;  4BGF A;  2CIO A;  4PAD A;  2XU3 A;  5CVN B;  4QRV A;  1AU3 A;  2Y5B A;  4YYV A;  4MSX A;  1AU0 A;  4BPV A;  3IMA A;  2H7J A;  1CS8 A;  1KHP A;  1CV8 A;  3KSE A;  2BDL A;  2HHN A;  2OUL A;  2F7D A;  2AUZ A;  3PW3 A;  4BS5 A;  4GUZ A;  1GMY A;  2DCD A;  1QMY A;  2NQA A;  4Q8G A;  3I3T A;  1AIM A;  1STF E;  1BP4 A;  4PP1 A;  2JQG R;  2E00 A;  1CPJ A;  5CHT A;  4YVA A;  4BS6 A;  1KXR A;  1TLO A;  3BOW A;  2YJB A;  2YJ9 A;  3USV A;  3E1Z B;  1Y08 A;  4W4U A;  5K16 A;  3K24 A;  4BSQ A;  1M6D A;  1YT7 A;  2G8E A;  1S4V A;  2DCC A;  3OF9 A;  4QBB A;  2WBF X;  2G8J A;  2R6N A;  2HD5 A;  1NB5 A;  3BC3 A;  1EWP A;  4OEL A;  5A24 A;  2XU5 A;  3P5X A;  3H89 A;  1F2C A;  3O0U A;  1PPP A;  3P5W A;  2AVW A;  1X9Y A;  1PIP A;  4MZO A;  1F2B A;  2VFC A;  1YAL A;  3N3K A;  2NQD B;  1IWD A;  4AXL A;  1F29 A;  1TL9 A;  1MEM A;  3QSD A;  4QRX A;  1PAD A;  2DCB A;  5JA7 A;  3H6S A;  1JQP A;  1NPZ A;  2HXZ A;  3WXF A;  3CH3 X;  3KKU A;  4NV8 A;  1PXV A;  3D6S A;  2AUX A;  3IHP A;  4FIP A;  4BQV A;  1ME4 A;  1PE6 A;  2O6X A;  5EF4 A;  1FH0 A;  2FO5 A;  1U9W A;  2DJF B;  4XUI A;  1MDW A;  2P86 A;  7PCK A;  4HWY A;  4I04 A;  4PI3 A;  2R9N A;  1GCB A;  3IEJ A;  1QOL A;  4X6J A;  1BQI A;  2R9O A;  4W5C A;  1EWL A;  4AXM A;  1PPO A;  1NL6 A;  2R9C A;  3D9W A;  3I06 A;  3ZUA A;  4YYU A;  4B55 A;  5F02 A;  1CSB B;  4CDD B;  2FRA A;  3CBJ A;  2GHU A;  3RVW A;  3S3R A;  2PNS A;  2DC7 A;  1KFU L;  3F75 A;  3RVX A;  2JQF R;  3LXS A;  4X6H A;  1AYV A;  1MS6 A;  1ZIV A;  2PAD A;  1K3B B;  3HHA A;  2E01 A;  2R9M A;  1GEC E;  3DF0 A;  2XU4 A;  3H7D A;  5JH3 A;  3BPF A;  4FJC A;  2DZY A;  1EWM A;  2FRQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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