1THEA

Crystal structures of recombinant rat cathepsin b and a cathepsin b-inhibitor complex: implications for structure-based inhibitor design
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
253
structure length
253
Chain Sequence
LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGARPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNADWGDNGFFKILRGENHCGIESEIVAGIPRT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of recombinant rat cathepsin B and a cathepsin B-inhibitor complex. Implications for structure-based inhibitor design.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Rattus norvegicus
molecule keywords Cathepsin B
total genus 75
structure length 253
sequence length 253
chains with identical sequence B
ec nomenclature ec 3.4.22.1: Cathepsin B.
pdb deposition date 1995-09-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1theA00
1PE6A 1GLOA 2YJ2A 1AYUA 1PBHA 2VHSA 2PBHA 4WA6A 1TU6A 2YJ8A 4YYRA 1CTEA 2F1GA 2R6NA 2IPPB 4YVAA 2PNSA 1VSNA 3BCNA 1U9XA 3PDFA 3OISA 3DF0A 1U9VA 1GECE 1A6RA 2FT2A 1GMYA 3IEJA 4N79A 4MZOA 9PAPA 3CBJA 1K3BB 3N4CA 3IMAA 5F02A 3N3KA 1CPJA 3K9MA 3OVXA 7PCKA 2GHUA 3NHEA 4OEMA 4AXLA 2O6XA 1ME4A 2OULA 1MHWA 2NQIA 3IV2A 2FTDA 3H8CA 1EWOA 3S3RA 1DF0A 1X9YA 5CHTA 4MZSA 5JA7A 1QOLA 3WXEA 1BP4A 2G8EA 1CV8A 3C9EA 2E02A 2DJFB 2HH5A 4BSQA 4Q8GA 3E1ZB 2HD5A 4YYQA 1NL6A 2DJGB 4BPVA 2DZZA 3GCBA 2DC6A 2P86A 4QRGA 2ATOA 2GFOA 3BPMA 5CVOB 2DZYA 2B1MA 1F2BA 3AI8A 1YT7A 1CJLA 1F2AA 4G54A 2XU1A 1TL9A 2JQGR 1PPOA 2R9MA 3LFYA 1KHQA 5J94A 3V6CA 5CHVA 4DMXA 4I07A 2XU3A 3BC3A 3MTNA 1S4VA 3H6SA 4BQVA 2AU1A 1AYWA 3B79A 3HD3A 1HUCB 4X6HA 2G7YA 3H89A 3S3QA 1CQDA 2E03A 2F7DA 2OZ2A 3OF9A 2YJ9A 3KWZA 5A24A 4W5BA 2P0RA 2ACTA 4YYSA 3HWNA 5FPWA 1CSBB 4MSXA 4YV8A 3MHHA 1FH0A 2AIMA 4HWYA 4PP1A 1ME3A 3H7DA 3P5UA 4N8WA 4XR7A 1KFUL 1KFXL 3RVVA 1KXRA 2BDZA 1NPZA 1MDWA 2XU4A 1BQIA 3I06A 3F75A 1F29A 4PI3A 1YK8A 3KWBX 1YALA 4CDEB 3QT4A 3ERVA 3OVZA 1BGOA 1PPDA 1GCBA 5JH3A 4BS6A 5CVNB 3IHPA 4KLBA 2OP3A 4X6IA 1O0EA 3KX1A 2YJBA 1MS6A 1Y4HA 3RVWA 1PIPA 2HXZA 4P6EA 1EWMA 2FRAA 4FJCA 1TLOA 2Y5BA 1PXVA 1POPA 3KW9A 5PADA 3OF8A 1QMYA 1CS8A 4AXMA 3CBKA 3QSDA 1VJVA 4P6GA 1YK7A 2ARYA 2DCDA 3V6EA 3PNRA 1SNKA 3PW3A 1YVBA 4PP2E 5EF4A 2AYOA 3CH2X 3QJ3A 2DCAA 4I04A 4BS5A 4N4ZA 2NQDB 1MEGA 2AVWA 1ITOA 1AIMA 1NQCA 1EWLA 3N3GA 2DC9A 2FUDA 1ZCMA 2FQ9A 3USVA 4I05A 2R9NA 4QH6A 1IWDA 1KHPA 3F5VA 3O0UA 3P5WA 4CDDB 3I3TA 2AS8A 3BOWA 2P7UA 3KFQA 8PCHA 4QBBA 3MHSA 1AU3A 2NQGA 4W5CA 1AECA 3U8EA 2NQAA 3PBHA 1CVZA 4FK5A 1MEMA 3ZUAA 1M6DA 2FYEA 4QRXA 4YYUA 1EWPA 3M99A 1ZIVA 3IOQA 4RY2A 1ATKA 4CDFB 2PREA 1AU4A 1JQPA 1NLJA 5EGWA 2C0YA 1DEUA 1STFE 5K16A 2IBIA 3WXFA 2R9OA 1QXPA 2R9FA 3K8UA 2E01A 4CZWA 4OELA 2B1NA 1AU0A 1PPPA 2CB5A 2AUZA 2G6DA 2HHNA 3D6SA 1PCIA 4ZUXU 3HHIA 4X6JA 1EF7A 2DC8A 4FIPA 3H8BA 2Y6EA 4Q8HA 2VHFA 3HHAA 3CH3X 2DCBA 1Q6KA 2AYNA 1QDQA 4K7CA 2JQFR 3KKUA 3IUTA 3P5XA 2H7JA 1F2CA 1PADA 2YJCA 2XU5A 6PADA 2BDLA 1NB3A 1U9WA 3BPFA 3BWKA 1ICFA 3P5VA 4XUIA 2G8JA 4W4UA 1NB5A 1THEA 1XKGA 1SP4B 1U5IA 4PADA 3O1GA 1AYVA 2E00A 3WXGA 2WBFX 5CVMA 1CB5A 4DMYA 4CDCB 2DC7A 2FRQA 1BY8A 3RVXA 1AU2A 1U9QX 2FO5A 2R9CA 4YYVA 3K24A 1PPNA 2AUXA 3LXSA 1Y08A 3MORA 2PADA 4YYWA 1MIRA 2CIOA 3TNXA 4QRVA 2DCCA 3KSEA
chains in the Genus database with same CATH superfamily
1PE6A 1GLOA 2YJ2A 1AYUA 1PBHA 2VHSA 2PBHA 4WA6A 1TU6A 2YJ8A 4YYRA 1CTEA 2F1GA 2R6NA 2IPPB 4YVAA 2PNSA 3PSEA 1VSNA 3BCNA 1U9XA 3PDFA 3OISA 4RF1A 3DF0A 1U9VA 3W30A 3BB7A 4P16A 1GECE 1A6RA 2FT2A 1GMYA 3IEJA 4N79A 4MZOA 9PAPA 1DKIA 3CBJA 3RNVA 4OW0A 1K3BB 3N4CA 3IMAA 5F02A 3N3KA 1CPJA 3K9MA 3OVXA 4A5UA 2GHUA 7PCKA 3NHEA 4OEMA 4AXLA 2O6XA 1ME4A 4BOQA 2OULA 1MHWA 2NQIA 3W31A 3IV2A 2FTDA 3H8CA 1EWOA 4XZXA 3S3RA 1DF0A 1X9YA 3PRPA 5CHTA 4MZSA 4WURA 5JA7A 1QOLA 3WXEA 1BP4A 2G8EA 1CV8A 3C9EA 5JZEA 2E02A 2DJFB 2HH5A 4BSQA 4PT5A 4RKXA 4HXDB 4Q8GA 3E1ZB 2HD5A 3B21A 4YYQA 1NL6A 2DJGB 4BPVA 4BOUA 2DZZA 3GCBA 3TMPA 2DC6A 2P86A 4QRGA 4D8BA 2ATOA 2GFOA 3BPMA 5CVOB 2BTWB 3BBAA 2DZYA 2B1MA 1F2BA 3AI8A 1YT7A 1CJLA 1F2AA 4G54A 1UKFA 2XU1A 1TL9A 3PRMA 2JQGR 1PPOA 2R9MA 3LFYA 1KHQA 5J94A 3V6CA 3OQCA 5CHVA 3PT2A 4DMXA 4I07A 2XU3A 2BU3A 3BC3A 3MTNA 1S4VA 3H6SA 4BQVA 2AU1A 1AYWA 3O65A 3B79A 3HD3A 1HUCB 2JRIA 4X6HA 2G7YA 3H89A 3S3QA 1CQDA 2E03A 2F7DA 2OZ2A 3OF9A 3BY4A 2YJ9A 3KWZA 5A24A 4W5BA 2P0RA 2ACTA 4YYSA 4D8EA 3MP2A 3HWNA 5FPWA 1CSBB 4MSXA 4OVZB 4YV8A 3MHHA 1FH0A 2AIMA 4HWYA 4PP1A 3E9SA 1ME3A 3H7DA 3P5UA 4N8WA 4XR7A 1KFUL 1KFXL 3MJ5A 3RVVA 1KXRA 2BDZA 1NPZA 1MDWA 2XU4A 1BQIA 3I06A 3F75A 1F29A 4PI3A 1YK8A 3KWBX 1YALA 4CDEB 3QT4A 3ERVA 3OVZA 4BOSA 4R3DA 1BGOA 1PPDA 1GCBA 5JH3A 4BS6A 5CVNB 3IHPA 4KLBA 5EZSA 4MM3B 2OP3A 4X6IA 1O0EA 3KX1A 2YJBA 1MS6A 1Y4HA 3RVWA 1PIPA 4MI7A 4REZA 2HXZA 4P6EA 1EWMA 2FRAA 4FJCA 2J7QA 1TLOA 2Y5BA 1PXVA 1POPA 3KW9A 2DOSA 5PADA 3OF8A 1QMYA 1PVJA 1CS8A 2AGAA 1YZBA 3CBKA 3QSDA 1VJVA 4P6GA 4AXMA 5KO3A 1YK7A 2ARYA 2DCDA 4ZTBA 3V6EA 3PNRA 1SNKA 3PW3A 2JTCA 2HWKA 1YVBA 4PP2E 5EF4A 2AYOA 3CH2X 3QJ3A 2DCAA 4I04A 4BS5A 4N4ZA 2NQDB 1MEGA 2AVWA 1ITOA 1AIMA 1NQCA 1EWLA 3N3GA 2DC9A 3IFUA 2FUDA 1ZCMA 2FQ9A 2BTWA 3USVA 4I05A 5EZQA 2R9NA 4QH6A 1IWDA 1KHPA 2J7QC 3F5VA 3P5WA 3O0UA 4CDDB 3I3TA 2AS8A 3BOWA 2P7UA 3KFQA 8PCHA 4QBBA 3PHXA 3ZNHA 3MHSA 1AU3A 2NQGA 4W5CA 4IP3A 1AECA 3U8EA 4RF0A 2NQAA 3PBHA 4IUMA 1CVZA 4FK5A 1MEMA 3ZUAA 1M6DA 2FYEA 2UZJA 4QRXA 4YYUA 1EWPA 3M99A 1ZIVA 3IOQA 4RY2A 1ATKA 3C0RA 4CDFB 5E6JA 2PREA 1AU4A 1JQPA 1NLJA 5EGWA 2C0YA 1DEUA 1STFE 5K16A 2IBIA 3WXFA 2R9OA 1QXPA 2R9FA 3K8UA 2E01A 4RNAA 4CZWA 4OELA 2B1NA 1AU0A 1PPPA 2CB5A 2AUZA 2G6DA 2HHNA 4OVZA 3D6SA 1PCIA 4ZUXU 3HHIA 4X6JA 4GUAA 1EF7A 2DC8A 4FIPA 3H8BA 2Y6EA 4Q8HA 2VHFA 3HHAA 3CH3X 2DCBA 1Q6KA 2AYNA 1QDQA 4K7CA 2JQFR 3KKUA 3IUTA 3P5XA 2Z84A 2H7JA 4BOZA 1F2CA 1PADA 2FE8A 2YJCA 2XU5A 6PADA 2BDLA 1NB3A 1U9WA 3BPFA 3BWKA 1ICFA 3P5VA 4XUIA 2G8JA 4W4UA 1NB5A 3MTVA 1THEA 1XKGA 1SP4B 1U5IA 3TRKA 4PADA 3O1GA 1AYVA 2E00A 3WXGA 2WBFX 5CVMA 3PHUA 1CB5A 4DMYA 4CDCB 2DC7A 2FRQA 1BY8A 3RVXA 1AU2A 1U9QX 2FO5A 3PHWA 2R9CA 4YYVA 4M0WA 3K24A 1PPNA 2AUXA 3LXSA 1Y08A 3MORA 4D8IA 2PADA 4YYWA 1MIRA 4BOPA 2CIOA 3TNXA 4QRVA 2DCCA 3KSEA
chains in the Genus database with same CATH topology
1PE6A 1GLOA 2YJ2A 1AYUA 1PBHA 2VHSA 2PBHA 4WA6A 1TU6A 2YJ8A 4YYRA 1CTEA 2F1GA 2R6NA 2IPPB 4YVAA 2PNSA 1VSNA 3BCNA 1U9XA 3PDFA 3OISA 3DF0A 1U9VA 1GX3A 1GECE 1A6RA 2FT2A 1GMYA 3IEJA 4N79A 4MZOA 9PAPA 3CBJA 4BGFA 1K3BB 3N4CA 3IMAA 5F02A 3N3KA 1CPJA 3K9MA 3OVXA 7PCKA 2GHUA 3NHEA 4OEMA 4AXLA 2O6XA 1ME4A 2OULA 1MHWA 2NQIA 3IV2A 2VFCA 2FTDA 3H8CA 1EWOA 3S3RA 1DF0A 1X9YA 5CHTA 4MZSA 5JA7A 1QOLA 3WXEA 1BP4A 2G8EA 1CV8A 3C9EA 2E02A 2DJFB 4NV7A 2HH5A 4BSQA 4Q8GA 3E1ZB 2HD5A 4YYQA 1NL6A 2DJGB 1W5RA 4BPVA 2DZZA 3GCBA 2DC6A 2P86A 4QRGA 2ATOA 2GFOA 3BPMA 5CVOB 2DZYA 2B1MA 1F2BA 3AI8A 1YT7A 1CJLA 1F2AA 4G54A 2XU1A 1TL9A 2JQGR 1PPOA 2R9MA 3LFYA 1KHQA 5J94A 3V6CA 5CHVA 4DMXA 4I07A 2XU3A 3BC3A 3MTNA 1S4VA 3H6SA 4BQVA 2AU1A 1AYWA 3B79A 3HD3A 1HUCB 1W4TA 4X6HA 2G7YA 3H89A 3S3QA 1CQDA 2E03A 2F7DA 2OZ2A 3OF9A 1W6FA 2YJ9A 3KWZA 5A24A 4W5BA 2P0RA 2ACTA 4YYSA 3HWNA 5FPWA 1CSBB 4MSXA 4YV8A 3MHHA 1FH0A 2AIMA 4HWYA 4PP1A 2VFBA 1ME3A 3H7DA 3P5UA 4N8WA 4XR7A 1KFUL 1KFXL 3RVVA 1KXRA 2BDZA 1NPZA 1MDWA 2XU4A 1BQIA 3I06A 3F75A 1F29A 4PI3A 1YK8A 3KWBX 1YALA 4CDEB 3QT4A 3ERVA 3OVZA 1BGOA 1PPDA 1GCBA 5JH3A 4BS6A 4C5PA 5CVNB 3IHPA 4KLBA 2OP3A 4X6IA 1O0EA 3KX1A 2YJBA 1MS6A 1Y4HA 3RVWA 1PIPA 2HXZA 4P6EA 1EWMA 2FRAA 4FJCA 1TLOA 2Y5BA 1PXVA 1POPA 3KW9A 5PADA 3OF8A 1QMYA 4B55A 1CS8A 4AXMA 3CBKA 3QSDA 1VJVA 4P6GA 1YK7A 2ARYA 3D9WA 2DCDA 3V6EA 3PNRA 1SNKA 3PW3A 1YVBA 4PP2E 5EF4A 2AYOA 4NV8A 3CH2X 3QJ3A 2DCAA 4I04A 4BS5A 4N4ZA 2NQDB 1MEGA 2AVWA 1ITOA 1AIMA 1NQCA 1EWLA 3N3GA 2DC9A 2FUDA 1ZCMA 2FQ9A 3USVA 4I05A 2R9NA 4QH6A 1IWDA 1KHPA 3F5VA 3P5WA 3O0UA 4CDDB 3I3TA 2AS8A 3BOWA 2P7UA 3KFQA 8PCHA 4QBBA 3MHSA 1AU3A 2NQGA 4W5CA 1AECA 3U8EA 2NQAA 3PBHA 1CVZA 4FK5A 1MEMA 3ZUAA 1M6DA 2FYEA 4QRXA 4YYUA 1EWPA 3M99A 1ZIVA 3IOQA 4RY2A 1ATKA 4CDFB 2PREA 1AU4A 1JQPA 1NLJA 5EGWA 2C0YA 1DEUA 1STFE 5K16A 2IBIA 3WXFA 2R9OA 1QXPA 2R9FA 3K8UA 2E01A 4CZWA 4OELA 2B1NA 1AU0A 1PPPA 2CB5A 2AUZA 2G6DA 2HHNA 3D6SA 1PCIA 4ZUXU 3HHIA 4X6JA 1EF7A 2DC8A 4FIPA 3H8BA 2Y6EA 4Q8HA 2VHFA 3HHAA 1E2TA 3CH3X 2DCBA 3LTWA 1Q6KA 2AYNA 1QDQA 4K7CA 2JQFR 3KKUA 3IUTA 3P5XA 2H7JA 1F2CA 1PADA 2YJCA 2XU5A 6PADA 2BDLA 1NB3A 4GUZA 1U9WA 3BPFA 3BWKA 1ICFA 3P5VA 4XUIA 2G8JA 4W4UA 1NB5A 1THEA 1XKGA 1SP4B 1U5IA 4PADA 3O1GA 1AYVA 2E00A 3WXGA 2WBFX 5CVMA 1CB5A 4DMYA 4CDCB 2DC7A 2FRQA 1BY8A 3RVXA 1AU2A 1U9QX 2FO5A 2BSZA 2R9CA 4YYVA 3K24A 1PPNA 2AUXA 3LXSA 1Y08A 3MORA 2PADA 4YYWA 1MIRA 2CIOA 3TNXA 4QRVA 2DCCA 3KSEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PE6 A;  1GLO A;  2YJ2 A;  1AYU A;  1PBH A;  2VHS A;  2PBH A;  4WA6 A;  1TU6 A;  2YJ8 A;  4YYR A;  1CTE A;  2F1G A;  2R6N A;  2IPP B;  4YVA A;  2PNS A;  1VSN A;  3BCN A;  1U9X A;  3PDF A;  3OIS A;  3DF0 A;  1U9V A;  1GEC E;  1A6R A;  2FT2 A;  1GMY A;  3IEJ A;  4N79 A;  4MZO A;  9PAP A;  3CBJ A;  1K3B B;  3N4C A;  3IMA A;  5F02 A;  3N3K A;  1CPJ A;  3K9M A;  3OVX A;  7PCK A;  2GHU A;  3NHE A;  4OEM A;  4AXL A;  2O6X A;  1ME4 A;  2OUL A;  1MHW A;  2NQI A;  3IV2 A;  2FTD A;  3H8C A;  1EWO A;  3S3R A;  1DF0 A;  1X9Y A;  5CHT A;  4MZS A;  5JA7 A;  1QOL A;  3WXE A;  1BP4 A;  2G8E A;  1CV8 A;  3C9E A;  2E02 A;  2DJF B;  2HH5 A;  4BSQ A;  4Q8G A;  3E1Z B;  2HD5 A;  4YYQ A;  1NL6 A;  2DJG B;  4BPV A;  2DZZ A;  3GCB A;  2DC6 A;  2P86 A;  4QRG A;  2ATO A;  2GFO A;  3BPM A;  5CVO B;  2DZY A;  2B1M A;  1F2B A;  3AI8 A;  1YT7 A;  1CJL A;  1F2A A;  4G54 A;  2XU1 A;  1TL9 A;  2JQG R;  1PPO A;  2R9M A;  3LFY A;  1KHQ A;  5J94 A;  3V6C A;  5CHV A;  4DMX A;  4I07 A;  2XU3 A;  3BC3 A;  3MTN A;  1S4V A;  3H6S A;  4BQV A;  2AU1 A;  1AYW A;  3B79 A;  3HD3 A;  1HUC B;  4X6H A;  2G7Y A;  3H89 A;  3S3Q A;  1CQD A;  2E03 A;  2F7D A;  2OZ2 A;  3OF9 A;  2YJ9 A;  3KWZ A;  5A24 A;  4W5B A;  2P0R A;  2ACT A;  4YYS A;  3HWN A;  5FPW A;  1CSB B;  4MSX A;  4YV8 A;  3MHH A;  1FH0 A;  2AIM A;  4HWY A;  4PP1 A;  1ME3 A;  3H7D A;  3P5U A;  4N8W A;  4XR7 A;  1KFU L;  1KFX L;  3RVV A;  1KXR A;  2BDZ A;  1NPZ A;  1MDW A;  2XU4 A;  1BQI A;  3I06 A;  3F75 A;  1F29 A;  4PI3 A;  1YK8 A;  3KWB X;  1YAL A;  4CDE B;  3QT4 A;  3ERV A;  3OVZ A;  1BGO A;  1PPD A;  1GCB A;  5JH3 A;  4BS6 A;  5CVN B;  3IHP A;  4KLB A;  2OP3 A;  4X6I A;  1O0E A;  3KX1 A;  2YJB A;  1MS6 A;  1Y4H A;  3RVW A;  1PIP A;  2HXZ A;  4P6E A;  1EWM A;  2FRA A;  4FJC A;  1TLO A;  2Y5B A;  1PXV A;  1POP A;  3KW9 A;  5PAD A;  3OF8 A;  1QMY A;  1CS8 A;  4AXM A;  3CBK A;  3QSD A;  1VJV A;  4P6G A;  1YK7 A;  2ARY A;  2DCD A;  3V6E A;  3PNR A;  1SNK A;  3PW3 A;  1YVB A;  4PP2 E;  5EF4 A;  2AYO A;  3CH2 X;  3QJ3 A;  2DCA A;  4I04 A;  4BS5 A;  4N4Z A;  2NQD B;  1MEG A;  2AVW A;  1ITO A;  1AIM A;  1NQC A;  1EWL A;  3N3G A;  2DC9 A;  2FUD A;  1ZCM A;  2FQ9 A;  3USV A;  4I05 A;  2R9N A;  4QH6 A;  1IWD A;  1KHP A;  3F5V A;  3O0U A;  3P5W A;  4CDD B;  3I3T A;  2AS8 A;  3BOW A;  2P7U A;  3KFQ A;  8PCH A;  4QBB A;  3MHS A;  1AU3 A;  2NQG A;  4W5C A;  1AEC A;  3U8E A;  2NQA A;  3PBH A;  1CVZ A;  4FK5 A;  1MEM A;  3ZUA A;  1M6D A;  2FYE A;  4QRX A;  4YYU A;  1EWP A;  3M99 A;  1ZIV A;  3IOQ A;  4RY2 A;  1ATK A;  4CDF B;  2PRE A;  1AU4 A;  1JQP A;  1NLJ A;  5EGW A;  2C0Y A;  1DEU A;  1STF E;  5K16 A;  2IBI A;  3WXF A;  2R9O A;  1QXP A;  2R9F A;  3K8U A;  2E01 A;  4CZW A;  4OEL A;  2B1N A;  1AU0 A;  1PPP A;  2CB5 A;  2AUZ A;  2G6D A;  2HHN A;  3D6S A;  1PCI A;  4ZUX U;  3HHI A;  4X6J A;  1EF7 A;  2DC8 A;  4FIP A;  3H8B A;  2Y6E A;  4Q8H A;  2VHF A;  3HHA A;  3CH3 X;  2DCB A;  1Q6K A;  2AYN A;  1QDQ A;  4K7C A;  2JQF R;  3KKU A;  3IUT A;  3P5X A;  2H7J A;  1F2C A;  1PAD A;  2YJC A;  2XU5 A;  6PAD A;  2BDL A;  1NB3 A;  1U9W A;  3BPF A;  3BWK A;  1ICF A;  3P5V A;  4XUI A;  2G8J A;  4W4U A;  1NB5 A;  1THE A;  1XKG A;  1SP4 B;  1U5I A;  4PAD A;  3O1G A;  1AYV A;  2E00 A;  3WXG A;  2WBF X;  5CVM A;  1CB5 A;  4DMY A;  4CDC B;  2DC7 A;  2FRQ A;  1BY8 A;  3RVX A;  1AU2 A;  1U9Q X;  2FO5 A;  2R9C A;  4YYV A;  3K24 A;  1PPN A;  2AUX A;  3LXS A;  1Y08 A;  3MOR A;  2PAD A;  4YYW A;  1MIR A;  2CIO A;  3TNX A;  4QRV A;  2DCC A;  3KSE A; 
#chains in the Genus database with same CATH topology
 1PE6 A;  1GLO A;  2YJ2 A;  1AYU A;  1PBH A;  2VHS A;  2PBH A;  4WA6 A;  1TU6 A;  2YJ8 A;  4YYR A;  1CTE A;  2F1G A;  2R6N A;  2IPP B;  4YVA A;  2PNS A;  3PSE A;  1VSN A;  3BCN A;  1U9X A;  3PDF A;  3OIS A;  4RF1 A;  3DF0 A;  1U9V A;  3W30 A;  3BB7 A;  4P16 A;  1GEC E;  1A6R A;  2FT2 A;  1GMY A;  3IEJ A;  4N79 A;  4MZO A;  9PAP A;  1DKI A;  3CBJ A;  3RNV A;  4OW0 A;  1K3B B;  3N4C A;  3IMA A;  5F02 A;  3N3K A;  1CPJ A;  3K9M A;  3OVX A;  4A5U A;  2GHU A;  7PCK A;  3NHE A;  4OEM A;  4AXL A;  2O6X A;  1ME4 A;  4BOQ A;  2OUL A;  1MHW A;  2NQI A;  3W31 A;  3IV2 A;  2FTD A;  3H8C A;  1EWO A;  4XZX A;  3S3R A;  1DF0 A;  1X9Y A;  3PRP A;  5CHT A;  4MZS A;  4WUR A;  5JA7 A;  1QOL A;  3WXE A;  1BP4 A;  2G8E A;  1CV8 A;  3C9E A;  5JZE A;  2E02 A;  2DJF B;  2HH5 A;  4BSQ A;  4PT5 A;  4RKX A;  4HXD B;  4Q8G A;  3E1Z B;  2HD5 A;  3B21 A;  4YYQ A;  1NL6 A;  2DJG B;  4BPV A;  4BOU A;  2DZZ A;  3GCB A;  3TMP A;  2DC6 A;  2P86 A;  4QRG A;  4D8B A;  2ATO A;  2GFO A;  3BPM A;  5CVO B;  2BTW B;  3BBA A;  2DZY A;  2B1M A;  1F2B A;  3AI8 A;  1YT7 A;  1CJL A;  1F2A A;  4G54 A;  1UKF A;  2XU1 A;  1TL9 A;  3PRM A;  2JQG R;  1PPO A;  2R9M A;  3LFY A;  1KHQ A;  5J94 A;  3V6C A;  3OQC A;  5CHV A;  3PT2 A;  4DMX A;  4I07 A;  2XU3 A;  2BU3 A;  3BC3 A;  3MTN A;  1S4V A;  3H6S A;  4BQV A;  2AU1 A;  1AYW A;  3O65 A;  3B79 A;  3HD3 A;  1HUC B;  2JRI A;  4X6H A;  2G7Y A;  3H89 A;  3S3Q A;  1CQD A;  2E03 A;  2F7D A;  2OZ2 A;  3OF9 A;  3BY4 A;  2YJ9 A;  3KWZ A;  5A24 A;  4W5B A;  2P0R A;  2ACT A;  4YYS A;  4D8E A;  3MP2 A;  3HWN A;  5FPW A;  1CSB B;  4MSX A;  4OVZ B;  4YV8 A;  3MHH A;  1FH0 A;  2AIM A;  4HWY A;  4PP1 A;  3E9S A;  1ME3 A;  3H7D A;  3P5U A;  4N8W A;  4XR7 A;  1KFU L;  1KFX L;  3MJ5 A;  3RVV A;  1KXR A;  2BDZ A;  1NPZ A;  1MDW A;  2XU4 A;  1BQI A;  3I06 A;  3F75 A;  1F29 A;  4PI3 A;  1YK8 A;  3KWB X;  1YAL A;  4CDE B;  3QT4 A;  3ERV A;  3OVZ A;  4BOS A;  4R3D A;  1BGO A;  1PPD A;  1GCB A;  5JH3 A;  4BS6 A;  5CVN B;  3IHP A;  4KLB A;  5EZS A;  4MM3 B;  2OP3 A;  4X6I A;  1O0E A;  3KX1 A;  2YJB A;  1MS6 A;  1Y4H A;  3RVW A;  1PIP A;  4MI7 A;  4REZ A;  2HXZ A;  4P6E A;  1EWM A;  2FRA A;  4FJC A;  2J7Q A;  1TLO A;  2Y5B A;  1PXV A;  1POP A;  3KW9 A;  2DOS A;  5PAD A;  3OF8 A;  1QMY A;  1PVJ A;  1CS8 A;  2AGA A;  1YZB A;  3CBK A;  3QSD A;  1VJV A;  4P6G A;  4AXM A;  5KO3 A;  1YK7 A;  2ARY A;  2DCD A;  4ZTB A;  3V6E A;  3PNR A;  1SNK A;  3PW3 A;  2JTC A;  2HWK A;  1YVB A;  4PP2 E;  5EF4 A;  2AYO A;  3CH2 X;  3QJ3 A;  2DCA A;  4I04 A;  4BS5 A;  4N4Z A;  2NQD B;  1MEG A;  2AVW A;  1ITO A;  1AIM A;  1NQC A;  1EWL A;  3N3G A;  2DC9 A;  3IFU A;  2FUD A;  1ZCM A;  2FQ9 A;  2BTW A;  3USV A;  4I05 A;  5EZQ A;  2R9N A;  4QH6 A;  1IWD A;  1KHP A;  2J7Q C;  3F5V A;  3P5W A;  3O0U A;  4CDD B;  3I3T A;  2AS8 A;  3BOW A;  2P7U A;  3KFQ A;  8PCH A;  4QBB A;  3PHX A;  3ZNH A;  3MHS A;  1AU3 A;  2NQG A;  4W5C A;  4IP3 A;  1AEC A;  3U8E A;  4RF0 A;  2NQA A;  3PBH A;  4IUM A;  1CVZ A;  4FK5 A;  1MEM A;  3ZUA A;  1M6D A;  2FYE A;  2UZJ A;  4QRX A;  4YYU A;  1EWP A;  3M99 A;  1ZIV A;  3IOQ A;  4RY2 A;  1ATK A;  3C0R A;  4CDF B;  5E6J A;  2PRE A;  1AU4 A;  1JQP A;  1NLJ A;  5EGW A;  2C0Y A;  1DEU A;  1STF E;  5K16 A;  2IBI A;  3WXF A;  2R9O A;  1QXP A;  2R9F A;  3K8U A;  2E01 A;  4RNA A;  4CZW A;  4OEL A;  2B1N A;  1AU0 A;  1PPP A;  2CB5 A;  2AUZ A;  2G6D A;  2HHN A;  4OVZ A;  3D6S A;  1PCI A;  4ZUX U;  3HHI A;  4X6J A;  4GUA A;  1EF7 A;  2DC8 A;  4FIP A;  3H8B A;  2Y6E A;  4Q8H A;  2VHF A;  3HHA A;  3CH3 X;  2DCB A;  1Q6K A;  2AYN A;  1QDQ A;  4K7C A;  2JQF R;  3KKU A;  3IUT A;  3P5X A;  2Z84 A;  2H7J A;  4BOZ A;  1F2C A;  1PAD A;  2FE8 A;  2YJC A;  2XU5 A;  6PAD A;  2BDL A;  1NB3 A;  1U9W A;  3BPF A;  3BWK A;  1ICF A;  3P5V A;  4XUI A;  2G8J A;  4W4U A;  1NB5 A;  3MTV A;  1THE A;  1XKG A;  1SP4 B;  1U5I A;  3TRK A;  4PAD A;  3O1G A;  1AYV A;  2E00 A;  3WXG A;  2WBF X;  5CVM A;  3PHU A;  1CB5 A;  4DMY A;  4CDC B;  2DC7 A;  2FRQ A;  1BY8 A;  3RVX A;  1AU2 A;  1U9Q X;  2FO5 A;  3PHW A;  2R9C A;  4YYV A;  4M0W A;  3K24 A;  1PPN A;  2AUX A;  3LXS A;  1Y08 A;  3MOR A;  4D8I A;  2PAD A;  4YYW A;  1MIR A;  4BOP A;  2CIO A;  3TNX A;  4QRV A;  2DCC A;  3KSE A; 
#chains in the Genus database with same CATH homology
 1PE6 A;  1GLO A;  2YJ2 A;  1AYU A;  1PBH A;  2VHS A;  2PBH A;  4WA6 A;  1TU6 A;  2YJ8 A;  4YYR A;  1CTE A;  2F1G A;  2R6N A;  2IPP B;  4YVA A;  2PNS A;  1VSN A;  3BCN A;  1U9X A;  3PDF A;  3OIS A;  3DF0 A;  1U9V A;  1GX3 A;  1GEC E;  1A6R A;  2FT2 A;  1GMY A;  3IEJ A;  4N79 A;  4MZO A;  9PAP A;  3CBJ A;  4BGF A;  1K3B B;  3N4C A;  3IMA A;  5F02 A;  3N3K A;  1CPJ A;  3K9M A;  3OVX A;  7PCK A;  2GHU A;  3NHE A;  4OEM A;  4AXL A;  2O6X A;  1ME4 A;  2OUL A;  1MHW A;  2NQI A;  3IV2 A;  2VFC A;  2FTD A;  3H8C A;  1EWO A;  3S3R A;  1DF0 A;  1X9Y A;  5CHT A;  4MZS A;  5JA7 A;  1QOL A;  3WXE A;  1BP4 A;  2G8E A;  1CV8 A;  3C9E A;  2E02 A;  2DJF B;  4NV7 A;  2HH5 A;  4BSQ A;  4Q8G A;  3E1Z B;  2HD5 A;  4YYQ A;  1NL6 A;  2DJG B;  1W5R A;  4BPV A;  2DZZ A;  3GCB A;  2DC6 A;  2P86 A;  4QRG A;  2ATO A;  2GFO A;  3BPM A;  5CVO B;  2DZY A;  2B1M A;  1F2B A;  3AI8 A;  1YT7 A;  1CJL A;  1F2A A;  4G54 A;  2XU1 A;  1TL9 A;  2JQG R;  1PPO A;  2R9M A;  3LFY A;  1KHQ A;  5J94 A;  3V6C A;  5CHV A;  4DMX A;  4I07 A;  2XU3 A;  3BC3 A;  3MTN A;  1S4V A;  3H6S A;  4BQV A;  2AU1 A;  1AYW A;  3B79 A;  3HD3 A;  1HUC B;  1W4T A;  4X6H A;  2G7Y A;  3H89 A;  3S3Q A;  1CQD A;  2E03 A;  2F7D A;  2OZ2 A;  3OF9 A;  1W6F A;  2YJ9 A;  3KWZ A;  5A24 A;  4W5B A;  2P0R A;  2ACT A;  4YYS A;  3HWN A;  5FPW A;  1CSB B;  4MSX A;  4YV8 A;  3MHH A;  1FH0 A;  2AIM A;  4HWY A;  4PP1 A;  2VFB A;  1ME3 A;  3H7D A;  3P5U A;  4N8W A;  4XR7 A;  1KFU L;  1KFX L;  3RVV A;  1KXR A;  2BDZ A;  1NPZ A;  1MDW A;  2XU4 A;  1BQI A;  3I06 A;  3F75 A;  1F29 A;  4PI3 A;  1YK8 A;  3KWB X;  1YAL A;  4CDE B;  3QT4 A;  3ERV A;  3OVZ A;  1BGO A;  1PPD A;  1GCB A;  5JH3 A;  4BS6 A;  4C5P A;  5CVN B;  3IHP A;  4KLB A;  2OP3 A;  4X6I A;  1O0E A;  3KX1 A;  2YJB A;  1MS6 A;  1Y4H A;  3RVW A;  1PIP A;  2HXZ A;  4P6E A;  1EWM A;  2FRA A;  4FJC A;  1TLO A;  2Y5B A;  1PXV A;  1POP A;  3KW9 A;  5PAD A;  3OF8 A;  1QMY A;  4B55 A;  1CS8 A;  4AXM A;  3CBK A;  3QSD A;  1VJV A;  4P6G A;  1YK7 A;  2ARY A;  3D9W A;  2DCD A;  3V6E A;  3PNR A;  1SNK A;  3PW3 A;  1YVB A;  4PP2 E;  5EF4 A;  2AYO A;  4NV8 A;  3CH2 X;  3QJ3 A;  2DCA A;  4I04 A;  4BS5 A;  4N4Z A;  2NQD B;  1MEG A;  2AVW A;  1ITO A;  1AIM A;  1NQC A;  1EWL A;  3N3G A;  2DC9 A;  2FUD A;  1ZCM A;  2FQ9 A;  3USV A;  4I05 A;  2R9N A;  4QH6 A;  1IWD A;  1KHP A;  3F5V A;  3P5W A;  3O0U A;  4CDD B;  3I3T A;  2AS8 A;  3BOW A;  2P7U A;  3KFQ A;  8PCH A;  4QBB A;  3MHS A;  1AU3 A;  2NQG A;  4W5C A;  1AEC A;  3U8E A;  2NQA A;  3PBH A;  1CVZ A;  4FK5 A;  1MEM A;  3ZUA A;  1M6D A;  2FYE A;  4QRX A;  4YYU A;  1EWP A;  3M99 A;  1ZIV A;  3IOQ A;  4RY2 A;  1ATK A;  4CDF B;  2PRE A;  1AU4 A;  1JQP A;  1NLJ A;  5EGW A;  2C0Y A;  1DEU A;  1STF E;  5K16 A;  2IBI A;  3WXF A;  2R9O A;  1QXP A;  2R9F A;  3K8U A;  2E01 A;  4CZW A;  4OEL A;  2B1N A;  1AU0 A;  1PPP A;  2CB5 A;  2AUZ A;  2G6D A;  2HHN A;  3D6S A;  1PCI A;  4ZUX U;  3HHI A;  4X6J A;  1EF7 A;  2DC8 A;  4FIP A;  3H8B A;  2Y6E A;  4Q8H A;  2VHF A;  3HHA A;  1E2T A;  3CH3 X;  2DCB A;  3LTW A;  1Q6K A;  2AYN A;  1QDQ A;  4K7C A;  2JQF R;  3KKU A;  3IUT A;  3P5X A;  2H7J A;  1F2C A;  1PAD A;  2YJC A;  2XU5 A;  6PAD A;  2BDL A;  1NB3 A;  4GUZ A;  1U9W A;  3BPF A;  3BWK A;  1ICF A;  3P5V A;  4XUI A;  2G8J A;  4W4U A;  1NB5 A;  1THE A;  1XKG A;  1SP4 B;  1U5I A;  4PAD A;  3O1G A;  1AYV A;  2E00 A;  3WXG A;  2WBF X;  5CVM A;  1CB5 A;  4DMY A;  4CDC B;  2DC7 A;  2FRQ A;  1BY8 A;  3RVX A;  1AU2 A;  1U9Q X;  2FO5 A;  2BSZ A;  2R9C A;  4YYV A;  3K24 A;  1PPN A;  2AUX A;  3LXS A;  1Y08 A;  3MOR A;  2PAD A;  4YYW A;  1MIR A;  2CIO A;  3TNX A;  4QRV A;  2DCC A;  3KSE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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