3C0RA

Structure of ovarian tumor (otu) domain in complex with ubiquitin
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
175
structure length
175
Chain Sequence
RVLKSTEMSIGGSGENVLSVHPVLDDNSCLFHAIAYGIFKQDSVRDLREMVSKEVLNNPVKFNDAILDKPNKDYAQWILKMESWGGAIEIGIISDALAVAIYVVDIDAVKIEKFNEDKFDNYILILFNGIHYDSLTMNEFKTVFNKNQPESDDVLTAALQLASNLKQTGYSFNTH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for ubiquitin recognition by the Otu1 ovarian tumor domain protein
pubmed doi rcsb
molecule tags Cell cycle, hydrolase
source organism Saccharomyces cerevisiae
molecule keywords Ubiquitin thioesterase OTU1
total genus 50
structure length 175
sequence length 175
chains with identical sequence C
ec nomenclature ec 3.4.19.12: Ubiquitinyl hydrolase 1.
pdb deposition date 2008-01-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02338 OTU OTU-like cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.80 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cathepsin B; Chain A 3c0rA00
4BOUA 3PHUA 3PRMA 5JZEA 3BY4A 3PHXA 3TMPA 3PHWA 3C0RA 4BOSA 4BOZA 3PT2A 4HXDB 4BOPA 4BOQA 3PRPA 3PSEA 3ZNHA
chains in the Genus database with same CATH superfamily
4OELA 4I05A 3N3GA 5FPWA 2AYNA 4CDDB 1CV8A 2OZ2A 4REZA 3C9EA 2XU1A 2E00A 1PPOA 2C0YA 2AYOA 2DC8A 3IV2A 4R3DA 1GMYA 3ERVA 1EF7A 2AVWA 3PT2A 4DMYA 3WXFA 4D8IA 3AI8A 2F7DA 1EWPA 1CPJA 1KFXL 3LFYA 4CDEB 2O6XA 6PADA 1QMYA 1NPZA 1NL6A 3IOQA 4I07A 4PT5A 4YYUA 1AYUA 1GCBA 3V6EA 3BPFA 2E03A 3BWKA 1MS6A 4BOUA 2DC9A 1ATKA 5EGWA 2DC7A 4PP1A 3PSEA 3QJ3A 4BS5A 2ACTA 2FUDA 3WXEA 4N8WA 3HD3A 3BOWA 3KFQA 4OW0A 1U5IA 3IHPA 3IUTA 4P6GA 4WURA 5EZSA 2DZZA 1KHQA 4AXLA 2JQFR 1QOLA 3BPMA 1CVZA 3E9SA 3MHHA 1ME3A 4BS6A 4HWYA 4MM3B 3BCNA 1TL9A 3PHWA 1CB5A 5KO3A 4X6IA 3WXGA 3MP2A 3H6SA 1NLJA 4RKXA 3ZNHA 2CB5A 5J94A 1Y08A 3I3TA 1YALA 3P5XA 4MI7A 5PADA 2DCAA 2IPPB 3ZUAA 4BQVA 2J7QA 3KKUA 3KW9A 2R9MA 2VHSA 3OF8A 1GLOA 1HUCB 4MZOA 1PPNA 4WA6A 3OF9A 5K16A 1X9YA 3D6SA 1CS8A 2XU3A 1TLOA 2R6NA 3BY4A 2IBIA 2E02A 3K9MA 4BOQA 4YYRA 1NB3A 1CJLA 1PPPA 3BC3A 3PHUA 2NQAA 2XU5A 4M0WA 3IMAA 2G8EA 3PNRA 3E1ZB 4CDFB 4YVAA 3P5WA 1SNKA 2YJ8A 2AS8A 1F2BA 1AYWA 3CH2X 4PI3A 2DJFB 4XZXA 1A6RA 3PHXA 7PCKA 1BY8A 3F75A 1CSBB 2YJCA 3H7DA 3PDFA 3GCBA 4ZTBA 2CIOA 3N3KA 1YT7A 4A5UA 1PIPA 5E6JA 4W5CA 5CVNB 4BPVA 2ARYA 3I06A 3O65A 3HHAA 2VHFA 3P5VA 5JZEA 1S4VA 5JH3A 3TMPA 4CDCB 3K24A 3KSEA 3W31A 3CH3X 1YK7A 3H89A 4KLBA 1M6DA 1F2AA 1Y4HA 2BU3A 2DCDA 2Y6EA 3B21A 1NB5A 4I04A 4PP2E 2JTCA 2JQGR 1DKIA 2Y5BA 1ZIVA 2DCCA 2R9OA 4PADA 4G54A 2PNSA 1VSNA 4FK5A 4AXMA 3F5VA 3IFUA 3TNXA 4MSXA 1EWOA 3BB7A 3MORA 2YJ2A 4D8BA 3O0UA 2J7QC 4YYWA 2DCBA 2H7JA 2DC6A 3KX1A 1AU0A 2PADA 1PE6A 1THEA 3B79A 3RVXA 1Q6KA 3H8CA 3PW3A 3PRPA 4X6HA 1EWMA 1YVBA 3HHIA 5EF4A 4QBBA 3RVWA 4N4ZA 5CHTA 4XUIA 3OISA 4BOSA 2G7YA 2XU4A 4BOPA 1CQDA 5CHVA 4BSQA 1K3BB 3OVXA 2OULA 4D8EA 1BP4A 2FO5A 2R9CA 4GUAA 1AIMA 2WBFX 3NHEA 1AYVA 1PVJA 4HXDB 4DMXA 4YV8A 1QXPA 3RVVA 3QT4A 2R9NA 3S3RA 4Q8GA 1UKFA 2Z84A 4ZUXU 3W30A 4OVZB 2FT2A 1DF0A 2FRQA 5EZQA 2PREA 3O1GA 1TU6A 1BQIA 4YYVA 3N4CA 4YYSA 2ATOA 4OVZA 3OVZA 3C0RA 2AGAA 5F02A 1CTEA 1IWDA 1PPDA 3HWNA 1SP4B 3KWZA 3MTNA 9PAPA 2P86A 1POPA 1U9QX 2GHUA 1VJVA 2PBHA 4IUMA 1EWLA 4XR7A 1KHPA 1PXVA 4IP3A 3CBKA 4CZWA 1AU4A 2NQDB 4N79A 4P16A 4W5BA 5CVMA 2OP3A 4RNAA 2UZJA 3M99A 2HH5A 1QDQA 2HD5A 3TRKA 2P7UA 5A24A 4MZSA 2B1NA 1AECA 1DEUA 1F29A 3P5UA 2FTDA 4W4UA 3IEJA 2NQIA 3V6CA 3KWBX 3PRMA 4RY2A 2AIMA 3PBHA 4YYQA 4RF1A 2AU1A 1ITOA 2R9FA 3OQCA 1BGOA 1YZBA 4QH6A 1MEMA 2BDZA 3MJ5A 4FJCA 1KFUL 4QRXA 1MDWA 2GFOA 2HWKA 3MTVA 2JRIA 1ME4A 2NQGA 5CVOB 2B1MA 2BTWB 2E01A 2BDLA 2G8JA 4FIPA 1MIRA 3USVA 1O0EA 3K8UA 5JA7A 2AUZA 8PCHA 1ZCMA 2FRAA 3QSDA 4OEMA 2BTWA 1U9WA 1PBHA 2FQ9A 3S3QA 2HXZA 2DJGB 1F2CA 3CBJA 1FH0A 1GECE 3U8EA 1JQPA 1YK8A 2HHNA 1NQCA 1ICFA 3LXSA 2DOSA 4QRVA 2FYEA 1PADA 1MHWA 1KXRA 4P6EA 4Q8HA 2AUXA 4RF0A 2DZYA 1AU3A 1U9VA 4K7CA 4BOZA 1MEGA 3H8BA 2G6DA 1AU2A 3DF0A 1PCIA 2P0RA 4X6JA 3MHSA 2YJBA 3BBAA 1STFE 1U9XA 1XKGA 2FE8A 2YJ9A 4QRGA 3RNVA 2F1GA
chains in the Genus database with same CATH topology
3PRMA 2J7QC 4REZA 4RF1A 3BY4A 3OQCA 4BOQA 1YZBA 4R3DA 3MJ5A 3PT2A 3PRPA 4D8IA 3PHUA 4M0WA 2HWKA 3MTVA 2JRIA 2BTWB 4PT5A 4BOSA 4BOPA 4XZXA 4BOUA 2BTWA 3PHXA 4D8EA 3PSEA 4GUAA 1PVJA 4HXDB 4ZTBA 4OW0A 1UKFA 2Z84A 3W30A 4OVZB 4A5UA 4WURA 5E6JA 5EZSA 5EZQA 3O65A 2DOSA 3E9SA 5JZEA 4OVZA 3TMPA 3C0RA 2AGAA 3W31A 4MM3B 4RF0A 3PHWA 2BU3A 3B21A 5KO3A 2JTCA 1DKIA 4BOZA 3MP2A 4RKXA 3ZNHA 4IUMA 4IP3A 4MI7A 3BBAA 4P16A 4RNAA 2FE8A 2J7QA 2UZJA 3TRKA 3IFUA 3RNVA 3BB7A 4D8BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BOU A;  3PHU A;  3PRM A;  5JZE A;  3BY4 A;  3PHX A;  3TMP A;  3PHW A;  3C0R A;  4BOS A;  4BOZ A;  3PT2 A;  4HXD B;  4BOP A;  4BOQ A;  3PRP A;  3PSE A;  3ZNH A; 
#chains in the Genus database with same CATH topology
 4OEL A;  4I05 A;  3N3G A;  5FPW A;  2AYN A;  4CDD B;  1CV8 A;  2OZ2 A;  4REZ A;  3C9E A;  2XU1 A;  2E00 A;  1PPO A;  2C0Y A;  2AYO A;  2DC8 A;  3IV2 A;  4R3D A;  1GMY A;  3ERV A;  1EF7 A;  2AVW A;  3PT2 A;  4DMY A;  3WXF A;  4D8I A;  3AI8 A;  2F7D A;  1EWP A;  1CPJ A;  1KFX L;  3LFY A;  4CDE B;  2O6X A;  6PAD A;  1QMY A;  1NPZ A;  1NL6 A;  3IOQ A;  4I07 A;  4PT5 A;  4YYU A;  1AYU A;  1GCB A;  3V6E A;  3BPF A;  2E03 A;  3BWK A;  1MS6 A;  4BOU A;  2DC9 A;  1ATK A;  5EGW A;  2DC7 A;  4PP1 A;  3PSE A;  3QJ3 A;  4BS5 A;  2ACT A;  2FUD A;  3WXE A;  4N8W A;  3HD3 A;  3BOW A;  3KFQ A;  4OW0 A;  1U5I A;  3IHP A;  3IUT A;  4P6G A;  4WUR A;  5EZS A;  2DZZ A;  1KHQ A;  4AXL A;  2JQF R;  1QOL A;  3BPM A;  1CVZ A;  3E9S A;  3MHH A;  1ME3 A;  4BS6 A;  4HWY A;  4MM3 B;  3BCN A;  1TL9 A;  3PHW A;  1CB5 A;  5KO3 A;  4X6I A;  3WXG A;  3MP2 A;  3H6S A;  1NLJ A;  4RKX A;  3ZNH A;  2CB5 A;  5J94 A;  1Y08 A;  3I3T A;  1YAL A;  3P5X A;  4MI7 A;  5PAD A;  2DCA A;  2IPP B;  3ZUA A;  4BQV A;  2J7Q A;  3KKU A;  3KW9 A;  2R9M A;  2VHS A;  3OF8 A;  1GLO A;  1HUC B;  4MZO A;  1PPN A;  4WA6 A;  3OF9 A;  5K16 A;  1X9Y A;  3D6S A;  1CS8 A;  2XU3 A;  1TLO A;  2R6N A;  3BY4 A;  2IBI A;  2E02 A;  3K9M A;  4BOQ A;  4YYR A;  1NB3 A;  1CJL A;  1PPP A;  3BC3 A;  3PHU A;  2NQA A;  2XU5 A;  4M0W A;  3IMA A;  2G8E A;  3PNR A;  3E1Z B;  4CDF B;  4YVA A;  3P5W A;  1SNK A;  2YJ8 A;  2AS8 A;  1F2B A;  1AYW A;  3CH2 X;  4PI3 A;  2DJF B;  4XZX A;  1A6R A;  3PHX A;  7PCK A;  1BY8 A;  3F75 A;  1CSB B;  2YJC A;  3H7D A;  3PDF A;  3GCB A;  4ZTB A;  2CIO A;  3N3K A;  1YT7 A;  4A5U A;  1PIP A;  5E6J A;  4W5C A;  5CVN B;  4BPV A;  2ARY A;  3I06 A;  3O65 A;  3HHA A;  2VHF A;  3P5V A;  5JZE A;  1S4V A;  5JH3 A;  3TMP A;  4CDC B;  3K24 A;  3KSE A;  3W31 A;  3CH3 X;  1YK7 A;  3H89 A;  4KLB A;  1M6D A;  1F2A A;  1Y4H A;  2BU3 A;  2DCD A;  2Y6E A;  3B21 A;  1NB5 A;  4I04 A;  4PP2 E;  2JTC A;  2JQG R;  1DKI A;  2Y5B A;  1ZIV A;  2DCC A;  2R9O A;  4PAD A;  4G54 A;  2PNS A;  1VSN A;  4FK5 A;  4AXM A;  3F5V A;  3IFU A;  3TNX A;  4MSX A;  1EWO A;  3BB7 A;  3MOR A;  2YJ2 A;  4D8B A;  3O0U A;  2J7Q C;  4YYW A;  2DCB A;  2H7J A;  2DC6 A;  3KX1 A;  1AU0 A;  2PAD A;  1PE6 A;  1THE A;  3B79 A;  3RVX A;  1Q6K A;  3H8C A;  3PW3 A;  3PRP A;  4X6H A;  1EWM A;  1YVB A;  3HHI A;  5EF4 A;  4QBB A;  3RVW A;  4N4Z A;  5CHT A;  4XUI A;  3OIS A;  4BOS A;  2G7Y A;  2XU4 A;  4BOP A;  1CQD A;  5CHV A;  4BSQ A;  1K3B B;  3OVX A;  2OUL A;  4D8E A;  1BP4 A;  2FO5 A;  2R9C A;  4GUA A;  1AIM A;  2WBF X;  3NHE A;  1AYV A;  1PVJ A;  4HXD B;  4DMX A;  4YV8 A;  1QXP A;  3RVV A;  3QT4 A;  2R9N A;  3S3R A;  4Q8G A;  1UKF A;  2Z84 A;  4ZUX U;  3W30 A;  4OVZ B;  2FT2 A;  1DF0 A;  2FRQ A;  5EZQ A;  2PRE A;  3O1G A;  1TU6 A;  1BQI A;  4YYV A;  3N4C A;  4YYS A;  2ATO A;  4OVZ A;  3OVZ A;  3C0R A;  2AGA A;  5F02 A;  1CTE A;  1IWD A;  1PPD A;  3HWN A;  1SP4 B;  3KWZ A;  3MTN A;  9PAP A;  2P86 A;  1POP A;  1U9Q X;  2GHU A;  1VJV A;  2PBH A;  4IUM A;  1EWL A;  4XR7 A;  1KHP A;  1PXV A;  4IP3 A;  3CBK A;  4CZW A;  1AU4 A;  2NQD B;  4N79 A;  4P16 A;  4W5B A;  5CVM A;  2OP3 A;  4RNA A;  2UZJ A;  3M99 A;  2HH5 A;  1QDQ A;  2HD5 A;  3TRK A;  2P7U A;  5A24 A;  4MZS A;  2B1N A;  1AEC A;  1DEU A;  1F29 A;  3P5U A;  2FTD A;  4W4U A;  3IEJ A;  2NQI A;  3V6C A;  3KWB X;  3PRM A;  4RY2 A;  2AIM A;  3PBH A;  4YYQ A;  4RF1 A;  2AU1 A;  1ITO A;  2R9F A;  3OQC A;  1BGO A;  1YZB A;  4QH6 A;  1MEM A;  2BDZ A;  3MJ5 A;  4FJC A;  1KFU L;  4QRX A;  1MDW A;  2GFO A;  2HWK A;  3MTV A;  2JRI A;  1ME4 A;  2NQG A;  5CVO B;  2B1M A;  2BTW B;  2E01 A;  2BDL A;  2G8J A;  4FIP A;  1MIR A;  3USV A;  1O0E A;  3K8U A;  5JA7 A;  2AUZ A;  8PCH A;  1ZCM A;  2FRA A;  3QSD A;  4OEM A;  2BTW A;  1U9W A;  1PBH A;  2FQ9 A;  3S3Q A;  2HXZ A;  2DJG B;  1F2C A;  3CBJ A;  1FH0 A;  1GEC E;  3U8E A;  1JQP A;  1YK8 A;  2HHN A;  1NQC A;  1ICF A;  3LXS A;  2DOS A;  4QRV A;  2FYE A;  1PAD A;  1MHW A;  1KXR A;  4P6E A;  4Q8H A;  2AUX A;  4RF0 A;  2DZY A;  1AU3 A;  1U9V A;  4K7C A;  4BOZ A;  1MEG A;  3H8B A;  2G6D A;  1AU2 A;  3DF0 A;  1PCI A;  2P0R A;  4X6J A;  3MHS A;  2YJB A;  3BBA A;  1STF E;  1U9X A;  1XKG A;  2FE8 A;  2YJ9 A;  4QRG A;  3RNV A;  2F1G A; 
#chains in the Genus database with same CATH homology
 3PRM A;  2J7Q C;  4REZ A;  4RF1 A;  3BY4 A;  3OQC A;  4BOQ A;  1YZB A;  4R3D A;  3MJ5 A;  3PT2 A;  3PRP A;  4D8I A;  3PHU A;  4M0W A;  2HWK A;  3MTV A;  2JRI A;  2BTW B;  4PT5 A;  4BOS A;  4BOP A;  4XZX A;  4BOU A;  2BTW A;  3PHX A;  4D8E A;  3PSE A;  4GUA A;  1PVJ A;  4HXD B;  4ZTB A;  4OW0 A;  1UKF A;  2Z84 A;  3W30 A;  4OVZ B;  4A5U A;  4WUR A;  5E6J A;  5EZS A;  5EZQ A;  3O65 A;  2DOS A;  3E9S A;  5JZE A;  4OVZ A;  3TMP A;  3C0R A;  2AGA A;  3W31 A;  4MM3 B;  4RF0 A;  3PHW A;  2BU3 A;  3B21 A;  5KO3 A;  2JTC A;  1DKI A;  4BOZ A;  3MP2 A;  4RKX A;  3ZNH A;  4IUM A;  4IP3 A;  4MI7 A;  3BBA A;  4P16 A;  4RNA A;  2FE8 A;  2J7Q A;  2UZJ A;  3TRK A;  3IFU A;  3RNV A;  3BB7 A;  4D8B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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