3BB7A

Structure of prevotella intermedia prointerpain a fragment 39-359 (mutant c154a)
Total Genus 89
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
321
structure length
314
Chain Sequence
ANQLRELKQTHTYTVFGYTDGGFAVISADDLAPELLGVSESNFVETDNPSFKWWLKAIDEVITNAVKSNKPLNVIKPDPSKYAAEVSTLLTTTWGQQMPYNKLLPKTKKGRLITGAVATATAQVLNYFKYPVRGIGSHTVHYPANDPSGVAISADFGNTTYDWANMKDNYSGNYTEAEANAVATLMLHCGVASEMQYGGPNEGSGAYMTDCAAGLRTYFGFTDAEYITRANYTDEQWMDIVFSELTKGHPLIYGGVDAGHAFVIDGYNKAGLVSVNWGWNGDVDGYYKIDLLNPGNMYSFTAEQDMVRGVYGKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A New Autocatalytic Activation Mechanism for Cysteine Proteases Revealed by Prevotella intermedia Interpain A
pubmed doi rcsb
molecule tags Hydrolase
source organism Prevotella intermedia
molecule keywords interpain A
total genus 89
structure length 314
sequence length 321
ec nomenclature
pdb deposition date 2007-11-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01640 Peptidase_C10 Peptidase C10 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.910.30 Alpha Beta 2-Layer Sandwich Protein Binding, DinI Protein; Chain A Protein Binding, DinI Protein; Chain A 3bb7A02
3.90.70.50 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cathepsin B; Chain A 3bb7A01
4D8EA 2UZJA 1DKIA 3BBAA 4RKXA 1PVJA 2JTCA 4D8IA 4D8BA 3BB7A
chains in the Genus database with same CATH superfamily
1YT7A 1YVBA 4CDEB 4W4UA 3MTNA 1O0EA 1TL9A 2FRQA 3PW3A 2OZ2A 1MIRA 1KXRA 3KX1A 1SG2A 2R9FA 4OW0A 4CDFB 1NQCA 3K24A 4YYSA 2FUDA 2AS8A 1KHPA 4YYQA 1CVZA 4D8BA 2B1NA 1CJLA 4XZXA 4Q8HA 2F1GA 2BTWA 1PPNA 2FE8A 4M0WA 1Q6KA 1VJVA 2GFOA 1ICFA 2G8JA 4I05A 3HHAA 3MP2A 4BS6A 4MI7A 3WXFA 3N3GA 3PBHA 1XKGA 4PP2E 1POPA 4AXMA 2DJGB 4MZSA 1PADA 1CTEA 2R9OA 4OELA 2BDZA 1U9QX 1DKIA 4X6JA 4KLBA 3GCBA 3PHWA 1BQIA 3QJ3A 5FPWA 1YZBA 1K3BB 4RF1A 2OP3A 2XU1A 2GHUA 3P5UA 2BU3A 3RVXA 3BY4A 4G54A 1U9VA 4K7CA 2G7YA 4QRGA 3IHPA 2AGAA 1GECE 4QRXA 2DCAA 2HWKA 1AYVA 3I3TA 2JQFR 4OVZB 1F29A 1BY8A 3OF9A 3RNVA 3IV2A 3MHHA 3P5VA 5CVNB 3H7DA 2YJ8A 4P6GA 2AVWA 4DMXA 2AIMA 2AYOA 4BQVA 1PPOA 4N8WA 5K16A 3HWNA 2XU5A 4YYWA 1UKFA 1FH0A 4RY2A 3ZNHA 9PAPA 2ARYA 4BPVA 2P86A 7PCKA 1AYUA 5JH3A 3KFQA 2J7QC 3O0UA 1ZCMA 3B21A 3NHEA 1MEGA 4YVAA 3H8CA 2O6XA 5J94A 2XU4A 2JTCA 2FYEA 3N3KA 1PPDA 2PADA 2AU1A 2NQDB 3HHIA 1QDQA 2NQIA 1MDWA 4YYVA 2E01A 1BGOA 3IEJA 2DC7A 3MTVA 2PREA 2HH5A 6PADA 3IFUA 3QT4A 5EF4A 1NB3A 4CDCB 2DZYA 4REZA 1AIMA 1SP4B 4MSXA 2JRIA 2E00A 3D6SA 3RVWA 3P5WA 1F2CA 3S3QA 4YYRA 4WURA 4BSQA 4RF0A 1PIPA 3E1ZB 1U5IA 2DOSA 2VHSA 4PI3A 1EWLA 1ATKA 3CH3X 3MHSA 2DJFB 3C9EA 4AXLA 2YJBA 1EWOA 1YK7A 1PXVA 2AYNA 3H89A 4W5BA 2H7JA 2HD5A 2CB5A 3PSEA 3U8EA 1M6DA 3E9SA 4IP3A 3WXEA 5JA7A 1DF0A 2ACTA 4BS5A 3F75A 3H6SA 4P6EA 4ZUXU 3BPMA 2R9CA 2DC9A 4PT5A 1X9YA 4OEMA 3N4CA 4FK5A 3PDFA 5EZSA 2HHNA 4BOQA 4ZTBA 5EZQA 2G6DA 4BOPA 3W31A 4MZOA 4BOZA 2PNSA 4X6IA 1CPJA 2FT2A 2YJ2A 3BPFA 4N4ZA 2NQAA 2R9MA 3M99A 2E02A 1GCBA 4BOSA 2C0YA 1SNKA 3LXSA 4D8EA 4YV8A 4FJCA 3OVZA 1AU2A 5CHTA 3MJ5A 2Y5BA 4QH6A 2FTDA 2PBHA 2P7UA 3PRPA 1GHHA 3AI8A 3P5XA 1ME3A 3IMAA 2DCBA 1Y08A 2UZJA 2R9NA 8PCHA 2YJCA 3WXGA 5KO3A 2DCCA 1KHQA 3CH2X 2BDLA 4MM3B 3BBAA 4PP1A 1EWMA 1PVJA 3TNXA 3CBKA 1EWPA 4RNAA 4WA6A 3CBJA 4IUMA 1YALA 3B79A 3PT2A 5A24A 1ITOA 1GMYA 1MHWA 1CS8A 5PADA 2ATOA 3PHUA 1QXPA 3BCNA 3S3RA 3TMPA 2F7DA 3IOQA 2WBFX 1AU4A 1CB5A 3OQCA 1U2MA 4YYUA 3W30A 3BWKA 4DMYA 2R6NA 1U9WA 4N79A 5CHVA 3BC3A 1IWDA 4QRVA 1S4VA 4W5CA 1KFUL 4D8IA 1AECA 4I07A 3PHXA 4QBBA 4EVXA 1NPZA 1QOLA 3KWBX 2BTWB 3F5VA 1PPPA 1QMYA 2AUZA 2P0RA 3BOWA 5F02A 3ERVA 2JQGR 3K9MA 3MORA 3BB7A 3O65A 2DCDA 2FQ9A 3PNRA 2J7QA 1U9XA 2AUXA 1EF7A 3RVVA 3I06A 1TLOA 1ZIVA 3KSEA 1AYWA 1MEMA 4XR7A 3QSDA 1AU0A 3USVA 2NQGA 4RKXA 3DF0A 2IBIA 4Q8GA 4X6HA 2DC8A 3KW9A 4KQTA 4HWYA 2E03A 4HXDB 4PADA 1NL6A 2XU3A 3HD3A 1PCIA 3V6EA 1CQDA 2G8EA 3ZUAA 1CV8A 4GUAA 2YJ9A 3H8BA 5EGWA 3OVXA 1KFXL 4A5UA 4R3DA 1F2BA 1THEA 1JQPA 3OISA 1ME4A 4OVZA 3IUTA 2IPPB 3TRKA 1Y4HA 4FIPA 1DEUA 3C0RA 3LFYA 2HXZA 1BP4A 5CVMA 1F2AA 1YK8A 1NB5A 2DC6A 1TU6A 2OULA 1MS6A 3OF8A 1GLOA 3KWZA 3V6CA 5JZEA 1STFE 1NLJA 1A6RA 2Y6EA 2CIOA 3K8UA 1PBHA 2B1MA 4I04A 2FO5A 2VHFA 1PE6A 3PRMA 4CZWA 2Z84A 4XUIA 1VSNA 4BOUA 1HUCB 5CVOB 3KKUA 5E6JA 4CDDB 1AU3A 1CSBB 4P16A 3O1GA 2FRAA 2DZZA
chains in the Genus database with same CATH topology
4PT5A 3BB7A 3O65A 2J7QA 5EZSA 4BOQA 4ZTBA 5EZQA 4BOPA 3W31A 1UKFA 3ZNHA 4BOZA 4OW0A 2J7QC 4RKXA 3B21A 4D8BA 4BOSA 2JTCA 4HXDB 4XZXA 4D8EA 2BTWA 3MJ5A 2FE8A 4M0WA 4GUAA 3PRPA 3MP2A 4MI7A 3MTVA 2UZJA 4A5UA 4R3DA 5KO3A 3IFUA 4MM3B 3BBAA 4OVZA 3TRKA 1PVJA 3C0RA 4REZA 4RNAA 1DKIA 2JRIA 3PHWA 4IUMA 3PT2A 1YZBA 4RF1A 4WURA 4RF0A 5JZEA 2DOSA 3PHUA 2BU3A 3TMPA 3BY4A 3PSEA 3OQCA 3W30A 3E9SA 4IP3A 2AGAA 3PRMA 2HWKA 2Z84A 4BOUA 4OVZB 4D8IA 5E6JA 3PHXA 4P16A 4EVXA 3RNVA 2BTWB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4D8E A;  2UZJ A;  1DKI A;  3BBA A;  4RKX A;  1PVJ A;  2JTC A;  4D8I A;  4D8B A;  3BB7 A; 
#chains in the Genus database with same CATH topology
 1YT7 A;  1YVB A;  4CDE B;  4W4U A;  3MTN A;  1O0E A;  1TL9 A;  2FRQ A;  3PW3 A;  2OZ2 A;  1MIR A;  1KXR A;  3KX1 A;  1SG2 A;  2R9F A;  4OW0 A;  4CDF B;  1NQC A;  3K24 A;  4YYS A;  2FUD A;  2AS8 A;  1KHP A;  4YYQ A;  1CVZ A;  4D8B A;  2B1N A;  1CJL A;  4XZX A;  4Q8H A;  2F1G A;  2BTW A;  1PPN A;  2FE8 A;  4M0W A;  1Q6K A;  1VJV A;  2GFO A;  1ICF A;  2G8J A;  4I05 A;  3HHA A;  3MP2 A;  4BS6 A;  4MI7 A;  3WXF A;  3N3G A;  3PBH A;  1XKG A;  4PP2 E;  1POP A;  4AXM A;  2DJG B;  4MZS A;  1PAD A;  1CTE A;  2R9O A;  4OEL A;  2BDZ A;  1U9Q X;  1DKI A;  4X6J A;  4KLB A;  3GCB A;  3PHW A;  1BQI A;  3QJ3 A;  5FPW A;  1YZB A;  1K3B B;  4RF1 A;  2OP3 A;  2XU1 A;  2GHU A;  3P5U A;  2BU3 A;  3RVX A;  3BY4 A;  4G54 A;  1U9V A;  4K7C A;  2G7Y A;  4QRG A;  3IHP A;  2AGA A;  1GEC E;  4QRX A;  2DCA A;  2HWK A;  1AYV A;  3I3T A;  2JQF R;  4OVZ B;  1F29 A;  1BY8 A;  3OF9 A;  3RNV A;  3IV2 A;  3MHH A;  3P5V A;  5CVN B;  3H7D A;  2YJ8 A;  4P6G A;  2AVW A;  4DMX A;  2AIM A;  2AYO A;  4BQV A;  1PPO A;  4N8W A;  5K16 A;  3HWN A;  2XU5 A;  4YYW A;  1UKF A;  1FH0 A;  4RY2 A;  3ZNH A;  9PAP A;  2ARY A;  4BPV A;  2P86 A;  7PCK A;  1AYU A;  5JH3 A;  3KFQ A;  2J7Q C;  3O0U A;  1ZCM A;  3B21 A;  3NHE A;  1MEG A;  4YVA A;  3H8C A;  2O6X A;  5J94 A;  2XU4 A;  2JTC A;  2FYE A;  3N3K A;  1PPD A;  2PAD A;  2AU1 A;  2NQD B;  3HHI A;  1QDQ A;  2NQI A;  1MDW A;  4YYV A;  2E01 A;  1BGO A;  3IEJ A;  2DC7 A;  3MTV A;  2PRE A;  2HH5 A;  6PAD A;  3IFU A;  3QT4 A;  5EF4 A;  1NB3 A;  4CDC B;  2DZY A;  4REZ A;  1AIM A;  1SP4 B;  4MSX A;  2JRI A;  2E00 A;  3D6S A;  3RVW A;  3P5W A;  1F2C A;  3S3Q A;  4YYR A;  4WUR A;  4BSQ A;  4RF0 A;  1PIP A;  3E1Z B;  1U5I A;  2DOS A;  2VHS A;  4PI3 A;  1EWL A;  1ATK A;  3CH3 X;  3MHS A;  2DJF B;  3C9E A;  4AXL A;  2YJB A;  1EWO A;  1YK7 A;  1PXV A;  2AYN A;  3H89 A;  4W5B A;  2H7J A;  2HD5 A;  2CB5 A;  3PSE A;  3U8E A;  1M6D A;  3E9S A;  4IP3 A;  3WXE A;  5JA7 A;  1DF0 A;  2ACT A;  4BS5 A;  3F75 A;  3H6S A;  4P6E A;  4ZUX U;  3BPM A;  2R9C A;  2DC9 A;  4PT5 A;  1X9Y A;  4OEM A;  3N4C A;  4FK5 A;  3PDF A;  5EZS A;  2HHN A;  4BOQ A;  4ZTB A;  5EZQ A;  2G6D A;  4BOP A;  3W31 A;  4MZO A;  4BOZ A;  2PNS A;  4X6I A;  1CPJ A;  2FT2 A;  2YJ2 A;  3BPF A;  4N4Z A;  2NQA A;  2R9M A;  3M99 A;  2E02 A;  1GCB A;  4BOS A;  2C0Y A;  1SNK A;  3LXS A;  4D8E A;  4YV8 A;  4FJC A;  3OVZ A;  1AU2 A;  5CHT A;  3MJ5 A;  2Y5B A;  4QH6 A;  2FTD A;  2PBH A;  2P7U A;  3PRP A;  1GHH A;  3AI8 A;  3P5X A;  1ME3 A;  3IMA A;  2DCB A;  1Y08 A;  2UZJ A;  2R9N A;  8PCH A;  2YJC A;  3WXG A;  5KO3 A;  2DCC A;  1KHQ A;  3CH2 X;  2BDL A;  4MM3 B;  3BBA A;  4PP1 A;  1EWM A;  1PVJ A;  3TNX A;  3CBK A;  1EWP A;  4RNA A;  4WA6 A;  3CBJ A;  4IUM A;  1YAL A;  3B79 A;  3PT2 A;  5A24 A;  1ITO A;  1GMY A;  1MHW A;  1CS8 A;  5PAD A;  2ATO A;  3PHU A;  1QXP A;  3BCN A;  3S3R A;  3TMP A;  2F7D A;  3IOQ A;  2WBF X;  1AU4 A;  1CB5 A;  3OQC A;  1U2M A;  4YYU A;  3W30 A;  3BWK A;  4DMY A;  2R6N A;  1U9W A;  4N79 A;  5CHV A;  3BC3 A;  1IWD A;  4QRV A;  1S4V A;  4W5C A;  1KFU L;  4D8I A;  1AEC A;  4I07 A;  3PHX A;  4QBB A;  4EVX A;  1NPZ A;  1QOL A;  3KWB X;  2BTW B;  3F5V A;  1PPP A;  1QMY A;  2AUZ A;  2P0R A;  3BOW A;  5F02 A;  3ERV A;  2JQG R;  3K9M A;  3MOR A;  3BB7 A;  3O65 A;  2DCD A;  2FQ9 A;  3PNR A;  2J7Q A;  1U9X A;  2AUX A;  1EF7 A;  3RVV A;  3I06 A;  1TLO A;  1ZIV A;  3KSE A;  1AYW A;  1MEM A;  4XR7 A;  3QSD A;  1AU0 A;  3USV A;  2NQG A;  4RKX A;  3DF0 A;  2IBI A;  4Q8G A;  4X6H A;  2DC8 A;  3KW9 A;  4KQT A;  4HWY A;  2E03 A;  4HXD B;  4PAD A;  1NL6 A;  2XU3 A;  3HD3 A;  1PCI A;  3V6E A;  1CQD A;  2G8E A;  3ZUA A;  1CV8 A;  4GUA A;  2YJ9 A;  3H8B A;  5EGW A;  3OVX A;  1KFX L;  4A5U A;  4R3D A;  1F2B A;  1THE A;  1JQP A;  3OIS A;  1ME4 A;  4OVZ A;  3IUT A;  2IPP B;  3TRK A;  1Y4H A;  4FIP A;  1DEU A;  3C0R A;  3LFY A;  2HXZ A;  1BP4 A;  5CVM A;  1F2A A;  1YK8 A;  1NB5 A;  2DC6 A;  1TU6 A;  2OUL A;  1MS6 A;  3OF8 A;  1GLO A;  3KWZ A;  3V6C A;  5JZE A;  1STF E;  1NLJ A;  1A6R A;  2Y6E A;  2CIO A;  3K8U A;  1PBH A;  2B1M A;  4I04 A;  2FO5 A;  2VHF A;  1PE6 A;  3PRM A;  4CZW A;  2Z84 A;  4XUI A;  1VSN A;  4BOU A;  1HUC B;  5CVO B;  3KKU A;  5E6J A;  4CDD B;  1AU3 A;  1CSB B;  4P16 A;  3O1G A;  2FRA A;  2DZZ A; 
#chains in the Genus database with same CATH homology
 4PT5 A;  3BB7 A;  3O65 A;  2J7Q A;  5EZS A;  4BOQ A;  4ZTB A;  5EZQ A;  4BOP A;  3W31 A;  1UKF A;  3ZNH A;  4BOZ A;  4OW0 A;  2J7Q C;  4RKX A;  3B21 A;  4D8B A;  4BOS A;  2JTC A;  4HXD B;  4XZX A;  4D8E A;  2BTW A;  3MJ5 A;  2FE8 A;  4M0W A;  4GUA A;  3PRP A;  3MP2 A;  4MI7 A;  3MTV A;  2UZJ A;  4A5U A;  4R3D A;  5KO3 A;  3IFU A;  4MM3 B;  3BBA A;  4OVZ A;  3TRK A;  1PVJ A;  3C0R A;  4REZ A;  4RNA A;  1DKI A;  2JRI A;  3PHW A;  4IUM A;  3PT2 A;  1YZB A;  4RF1 A;  4WUR A;  4RF0 A;  5JZE A;  2DOS A;  3PHU A;  2BU3 A;  3TMP A;  3BY4 A;  3PSE A;  3OQC A;  3W30 A;  3E9S A;  4IP3 A;  2AGA A;  3PRM A;  2HWK A;  2Z84 A;  4BOU A;  4OVZ B;  4D8I A;  5E6J A;  3PHX A;  4P16 A;  4EVX A;  3RNV A;  2BTW B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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