1F2BA

Crystal structure analysis of cruzain bound to vinyl sulfone derived inhibitor (iii)
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
215
structure length
215
Chain Sequence
APAAVDWRARGAVTAVKDQGQCGSCWAFSAIGNVECQWFLAGHPLTNLSEQMLVSCDKTDSGCSGGLMNNAFEWIVQENNGAVYTEDSYPYASGEGISPPCTTSGHTVGATITGHVELPQDEAQIAAWLAVNGPVAVAVDASSWMTYTGGVMTSCVSEQLDHGVLLVGYNDSAAVPYWIIKNSWTTQWGEEGYIRIAKGSNQCLVKEEASSAVVG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A target within the target: probing cruzain's P1' site to define structural determinants for the Chagas' disease protease.
pubmed doi rcsb
molecule keywords CRUZAIN
molecule tags Hydrolase
source organism Trypanosoma cruzi
total genus 66
structure length 215
sequence length 215
ec nomenclature ec 3.4.22.51: Cruzipain.
pdb deposition date 2000-05-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1f2bA00
2DC6A 4X6IA 3IUTA 1EWPA 3M99A 1Q6KA 3WXGA 5JA7A 7PCKA 3BPFA 1QDQA 4PI3A 3S3QA 1HUCB 4PP1A 1PPOA 5CVOB 3P5XA 1AYVA 1EF7A 4YYWA 3OVXA 3O1GA 1ATKA 2P7UA 3HD3A 3N4CA 2AYNA 1AU0A 2O6XA 3PW3A 4QH6A 5F02A 5J94A 2ACTA 4N4ZA 2G7YA 2R9MA 1PBHA 4MZOA 2OULA 3HHAA 2F7DA 3WXFA 4WA6A 1PADA 1ZCMA 1CSBB 2HXZA 1U9QX 2CIOA 1KFXL 3K9MA 3IV2A 3K8UA 1SNKA 3OF8A 2DC7A 4CDFB 2B1NA 2FRAA 2XU5A 3KSEA 1GCBA 1PXVA 2G8EA 2HH5A 3IMAA 3U8EA 3KFQA 1EWMA 2DC8A 1U9VA 2NQGA 1CPJA 3WXEA 1NPZA 2DC9A 3LXSA 1DEUA 4FIPA 3RVVA 3DF0A 4W5CA 3MHSA 3CBJA 4YYSA 1X9YA 4DMYA 4DMXA 5PADA 1AYWA 4QRGA 1BQIA 1QXPA 4Q8HA 4ZUXU 3IOQA 1AU4A 1EWOA 1PPPA 1KFUL 4BQVA 6PADA 5FPWA 1CQDA 1MEMA 2P0RA 1AIMA 1AU2A 2B1MA 4CDDB 2CB5A 1F2BA 3TNXA 2R9CA 2WBFX 1GECE 3K24A 4BSQA 2E02A 1Y4HA 2DJFB 1CJLA 4I04A 2IPPB 1CTEA 2JQFR 5CVNB 4AXMA 3IHPA 1GMYA 1KXRA 3P5VA 3USVA 4MSXA 4FJCA 3N3GA 1S4VA 1FH0A 3KWBX 3QJ3A 2PREA 1XKGA 1YK8A 2DCBA 2BDZA 3V6EA 2FT2A 5K16A 3MHHA 3F75A 2AUZA 2YJ8A 3C9EA 2DZYA 1NB3A 2PADA 1MEGA 2G6DA 1O0EA 1U5IA 3S3RA 3P5WA 2DJGB 1PIPA 1DF0A 2IBIA 3F5VA 4RY2A 1AU3A 4QBBA 4XR7A 1NB5A 2AUXA 3PNRA 2AIMA 2P86A 1TL9A 2R9NA 2FRQA 4W5BA 3I06A 5JH3A 1JQPA 1PPDA 3LFYA 1M6DA 1ME3A 2Y6EA 2PNSA 4QRXA 4AXLA 2XU3A 2F1GA 3BWKA 1NL6A 4YYQA 4YVAA 4CDEB 3ZUAA 1MHWA 1BGOA 2Y5BA 2GHUA 2JQGR 1QOLA 3PBHA 3HWNA 1GLOA 2BDLA 3CBKA 3GCBA 4YYVA 3IEJA 2YJ2A 4X6JA 3OF9A 3RVWA 2AVWA 3OISA 4MZSA 1IWDA 4QRVA 5CVMA 1CB5A 3MTNA 4N79A 2YJCA 3ERVA 4I05A 2VHFA 1THEA 2R6NA 2OP3A 2NQAA 1AECA 1STFE 4N8WA 1ME4A 1TLOA 5CHTA 5EF4A 3OVZA 3QT4A 1VJVA 1MIRA 3BC3A 1ZIVA 4W4UA 3KKUA 2GFOA 2FYEA 4YV8A 4OEMA 3NHEA 1MS6A 2DCDA 4KLBA 1CV8A 2DCCA 1KHPA 2DZZA 4YYRA 3CH2X 2C0YA 2H7JA 3KW9A 3BCNA 1CS8A 2ARYA 2HD5A 2XU1A 3AI8A 2E03A 2YJBA 4PADA 2HHNA 4BPVA 1CVZA 3D6SA 4CDCB 1PCIA 9PAPA 1ICFA 1YALA 3KX1A 2FUDA 1A6RA 4CZWA 2R9OA 3QSDA 4I07A 1MDWA 1F2AA 1PPNA 1F29A 2DCAA 3N3KA 3O0UA 1PE6A 1YVBA 1U9WA 1YK7A 4BS5A 1TU6A 2FTDA 3H7DA 4HWYA 2OZ2A 2NQDB 4PP2E 4XUIA 4X6HA 3H8CA 2E00A 5CHVA 2R9FA 4OELA 5A24A 3MORA 2VHSA 1NQCA 2YJ9A 1U9XA 1AYUA 5EGWA 3KWZA 1QMYA 1KHQA 2AS8A 3HHIA 1POPA 2AYOA 3RVXA 1K3BB 3BOWA 1BP4A 1SP4B 4P6GA 1VSNA 4Q8GA 4FK5A 2G8JA 3E1ZB 1ITOA 3H8BA 2FQ9A 1F2CA 1YT7A 3H6SA 1EWLA 2NQIA 1Y08A 8PCHA 3BPMA 2FO5A 1NLJA 3H89A 2XU4A 3B79A 3CH3X 4K7CA 2AU1A 2PBHA 3P5UA 3PDFA 4G54A 4P6EA 4BS6A 3V6CA 1BY8A 2ATOA 4YYUA 2E01A 3I3TA
chains in the Genus database with same CATH superfamily
2DC6A 4X6IA 3IUTA 3PRMA 1EWPA 3M99A 1Q6KA 3WXGA 5JA7A 2Z84A 7PCKA 2AGAA 3BPFA 1QDQA 3IFUA 4OVZB 4PI3A 3S3QA 1HUCB 4PP1A 1PPOA 5CVOB 4BOPA 3P5XA 1AYVA 1EF7A 4YYWA 3OVXA 3O1GA 1ATKA 2P7UA 3HD3A 2BU3A 2HWKA 3N4CA 2AYNA 3MP2A 1AU0A 2O6XA 3E9SA 3PW3A 4QH6A 5F02A 5J94A 4RNAA 3RNVA 2ACTA 2FE8A 4N4ZA 2G7YA 2R9MA 1PBHA 3BB7A 4MZOA 2OULA 3HHAA 2F7DA 3WXFA 4WA6A 1PADA 1ZCMA 1CSBB 2HXZA 1U9QX 2CIOA 1KFXL 3K9MA 3IV2A 3K8UA 1SNKA 3OF8A 2DC7A 4CDFB 2B1NA 2FRAA 2XU5A 3KSEA 1GCBA 1PXVA 2G8EA 2HH5A 3IMAA 3U8EA 3KFQA 1EWMA 2DC8A 1U9VA 2NQGA 1CPJA 3WXEA 1NPZA 2DC9A 3LXSA 1DEUA 4FIPA 3RVVA 3DF0A 4W5CA 3MHSA 3CBJA 4YYSA 1X9YA 4DMYA 4DMXA 5PADA 1AYWA 4QRGA 1BQIA 1QXPA 4Q8HA 4IP3A 4ZUXU 3IOQA 4BOQA 1AU4A 2BTWB 1EWOA 1PPPA 1KFUL 4BQVA 2DOSA 5KO3A 6PADA 5FPWA 1CQDA 1MEMA 2P0RA 4OW0A 1AIMA 1AU2A 2B1MA 4CDDB 2CB5A 1F2BA 3TNXA 2R9CA 2WBFX 1GECE 3K24A 4BSQA 2E02A 1Y4HA 4RKXA 2DJFB 4GUAA 1CJLA 4I04A 2IPPB 4ZTBA 4MM3B 1CTEA 3PHWA 3BY4A 2JQFR 5CVNB 4AXMA 3IHPA 1GMYA 1KXRA 3P5VA 3USVA 4MSXA 4FJCA 3PT2A 3N3GA 4MI7A 4D8EA 2JTCA 1S4VA 1FH0A 3KWBX 4BOSA 3QJ3A 2PREA 1XKGA 1YK8A 2DCBA 2BDZA 3V6EA 2FT2A 5K16A 2BTWA 3F75A 3MHHA 2AUZA 2YJ8A 3C9EA 3ZNHA 2DZYA 5EZQA 1NB3A 2PADA 1MEGA 2G6DA 1O0EA 1U5IA 3S3RA 3P5WA 2DJGB 4A5UA 1PIPA 1DF0A 2IBIA 3F5VA 4RY2A 3TRKA 1AU3A 4QBBA 4XR7A 1NB5A 2AUXA 3PNRA 2AIMA 1UKFA 2P86A 1TL9A 2R9NA 2FRQA 4W5BA 3I06A 5JH3A 1JQPA 4OVZA 1PPDA 3LFYA 1M6DA 1ME3A 2Y6EA 2PNSA 3OQCA 2J7QA 4QRXA 4AXLA 2XU3A 2F1GA 3BWKA 1NL6A 4YYQA 4HXDB 4YVAA 4CDEB 3ZUAA 1MHWA 1BGOA 2Y5BA 2GHUA 2JQGR 1PVJA 1QOLA 3PBHA 3HWNA 2J7QC 5JZEA 1GLOA 2BDLA 4RF1A 3CBKA 3GCBA 4YYVA 3IEJA 4P16A 2YJ2A 4X6JA 3OF9A 3RVWA 2AVWA 3OISA 4MZSA 1IWDA 4QRVA 5CVMA 4M0WA 1CB5A 3MTNA 4N79A 5EZSA 2YJCA 3ERVA 4I05A 4BOUA 2VHFA 1THEA 3B21A 4PT5A 2R6NA 3MJ5A 2OP3A 2NQAA 1AECA 3PRPA 1STFE 4N8WA 1ME4A 1TLOA 5CHTA 5EF4A 4REZA 3OVZA 3QT4A 1VJVA 1MIRA 3BC3A 1ZIVA 4W4UA 3KKUA 2GFOA 2FYEA 4YV8A 4OEMA 3NHEA 1MS6A 2DCDA 4KLBA 1CV8A 2DCCA 4WURA 1KHPA 2DZZA 4YYRA 3CH2X 2C0YA 2H7JA 3KW9A 3BCNA 1CS8A 2ARYA 2HD5A 2XU1A 3AI8A 2E03A 3W30A 2YJBA 4PADA 2JRIA 2HHNA 3MTVA 1CVZA 3D6SA 4BPVA 4CDCB 1PCIA 4D8BA 9PAPA 3O65A 1ICFA 1YALA 3KX1A 2FUDA 1A6RA 4CZWA 2UZJA 2R9OA 3QSDA 3PHUA 4I07A 1MDWA 3BBAA 1F2AA 1PPNA 1F29A 2DCAA 3N3KA 3O0UA 1PE6A 1YVBA 1U9WA 1YK7A 4BS5A 1TU6A 2FTDA 3H7DA 4IUMA 4HWYA 2OZ2A 2NQDB 4PP2E 4XUIA 4X6HA 5E6JA 3H8CA 2E00A 5CHVA 2R9FA 4OELA 5A24A 3MORA 2VHSA 1NQCA 1YZBA 2YJ9A 1DKIA 1U9XA 1AYUA 4BOZA 3W31A 4D8IA 5EGWA 3KWZA 1QMYA 1KHQA 2AS8A 3HHIA 1POPA 2AYOA 3RVXA 1K3BB 3BOWA 1BP4A 1SP4B 4P6GA 1VSNA 4Q8GA 4R3DA 4FK5A 2G8JA 3E1ZB 1ITOA 3H8BA 2FQ9A 1F2CA 1YT7A 3H6SA 1EWLA 2NQIA 1Y08A 3C0RA 8PCHA 3BPMA 2FO5A 4RF0A 1NLJA 3H89A 2XU4A 3B79A 3CH3X 4K7CA 2AU1A 2PBHA 3P5UA 4XZXA 3PDFA 4G54A 3PHXA 4P6EA 4BS6A 3V6CA 1BY8A 3TMPA 3PSEA 2ATOA 4YYUA 2E01A 3I3TA
chains in the Genus database with same CATH topology
2DC6A 4X6IA 3IUTA 1EWPA 3M99A 1Q6KA 3WXGA 5JA7A 7PCKA 3BPFA 1QDQA 4PI3A 3S3QA 1HUCB 4PP1A 1PPOA 5CVOB 3P5XA 1AYVA 1EF7A 4YYWA 3OVXA 3O1GA 1ATKA 2P7UA 1W5RA 1E2TA 3HD3A 3N4CA 2AYNA 1AU0A 2O6XA 3PW3A 4QH6A 5F02A 5J94A 2ACTA 4N4ZA 2G7YA 2R9MA 1PBHA 4MZOA 1W6FA 2OULA 3HHAA 4BGFA 2F7DA 3WXFA 4WA6A 1PADA 1ZCMA 1CSBB 2HXZA 1U9QX 2CIOA 4NV7A 1KFXL 3K9MA 3IV2A 3K8UA 1SNKA 3OF8A 2DC7A 4CDFB 2B1NA 2FRAA 2XU5A 3KSEA 1GCBA 1PXVA 2G8EA 2HH5A 3IMAA 3U8EA 3KFQA 1EWMA 2DC8A 1U9VA 2NQGA 1CPJA 3WXEA 1NPZA 2DC9A 3LXSA 1DEUA 4FIPA 3RVVA 3DF0A 4W5CA 3MHSA 3CBJA 4YYSA 1X9YA 4DMYA 4DMXA 5PADA 1AYWA 4QRGA 1BQIA 1QXPA 4Q8HA 4ZUXU 3IOQA 1AU4A 1EWOA 2BSZA 1PPPA 1KFUL 4BQVA 6PADA 5FPWA 1CQDA 1MEMA 2P0RA 1AIMA 1AU2A 2B1MA 4CDDB 2CB5A 1F2BA 1GX3A 3TNXA 2R9CA 2WBFX 1GECE 3K24A 4BSQA 2E02A 1Y4HA 2DJFB 1CJLA 4I04A 2IPPB 1CTEA 2JQFR 5CVNB 4AXMA 3IHPA 1GMYA 1KXRA 3P5VA 3USVA 4C5PA 2VFBA 4MSXA 4FJCA 3N3GA 1S4VA 1FH0A 3KWBX 3QJ3A 2PREA 1XKGA 1YK8A 2DCBA 2BDZA 3V6EA 2FT2A 5K16A 3MHHA 3F75A 2AUZA 2YJ8A 3C9EA 2DZYA 1NB3A 2PADA 1MEGA 2G6DA 1O0EA 1U5IA 3S3RA 3P5WA 2DJGB 2VFCA 1PIPA 1DF0A 2IBIA 3F5VA 4RY2A 1AU3A 4QBBA 4XR7A 1NB5A 2AUXA 3PNRA 2AIMA 2P86A 1TL9A 2R9NA 2FRQA 4W5BA 3I06A 5JH3A 1JQPA 1PPDA 3LFYA 1M6DA 1ME3A 2Y6EA 2PNSA 3D9WA 4QRXA 4AXLA 2XU3A 2F1GA 3BWKA 1NL6A 4YYQA 4YVAA 4CDEB 3ZUAA 1MHWA 1BGOA 2Y5BA 2GHUA 2JQGR 1QOLA 3PBHA 3HWNA 1GLOA 2BDLA 3CBKA 3GCBA 4YYVA 3IEJA 2YJ2A 4X6JA 3OF9A 3RVWA 2AVWA 3OISA 4MZSA 1IWDA 4QRVA 5CVMA 1CB5A 3MTNA 4N79A 2YJCA 3ERVA 4I05A 2VHFA 1THEA 2R6NA 2OP3A 2NQAA 1AECA 1STFE 4N8WA 1ME4A 1TLOA 5CHTA 5EF4A 3OVZA 3QT4A 1VJVA 1MIRA 3BC3A 1W4TA 1ZIVA 4W4UA 3KKUA 2GFOA 2FYEA 4YV8A 4OEMA 3NHEA 1MS6A 2DCDA 4KLBA 1CV8A 2DCCA 1KHPA 2DZZA 4YYRA 3CH2X 2C0YA 2H7JA 3KW9A 3BCNA 1CS8A 2ARYA 2HD5A 2XU1A 3AI8A 2E03A 2YJBA 4PADA 2HHNA 4BPVA 1CVZA 3D6SA 4CDCB 1PCIA 9PAPA 1ICFA 1YALA 3KX1A 2FUDA 1A6RA 4CZWA 2R9OA 3QSDA 4B55A 4I07A 1MDWA 1F2AA 1PPNA 1F29A 2DCAA 3N3KA 3O0UA 1PE6A 1YVBA 1U9WA 1YK7A 4BS5A 1TU6A 2FTDA 3H7DA 4HWYA 2OZ2A 2NQDB 4NV8A 4PP2E 4XUIA 4X6HA 3H8CA 2E00A 5CHVA 2R9FA 4OELA 5A24A 3MORA 2VHSA 1NQCA 2YJ9A 1U9XA 1AYUA 5EGWA 3KWZA 1QMYA 1KHQA 2AS8A 3HHIA 1POPA 2AYOA 3RVXA 1K3BB 3BOWA 1BP4A 1SP4B 4P6GA 1VSNA 4Q8GA 4FK5A 2G8JA 3E1ZB 1ITOA 3H8BA 2FQ9A 1F2CA 1YT7A 3H6SA 1EWLA 2NQIA 1Y08A 8PCHA 3BPMA 2FO5A 1NLJA 3H89A 2XU4A 3B79A 3CH3X 4K7CA 2AU1A 2PBHA 3P5UA 3PDFA 4G54A 4P6EA 4BS6A 4GUZA 3V6CA 1BY8A 2ATOA 4YYUA 2E01A 3I3TA 3LTWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DC6 A;  4X6I A;  3IUT A;  1EWP A;  3M99 A;  1Q6K A;  3WXG A;  5JA7 A;  7PCK A;  3BPF A;  1QDQ A;  4PI3 A;  3S3Q A;  1HUC B;  4PP1 A;  1PPO A;  5CVO B;  3P5X A;  1AYV A;  1EF7 A;  4YYW A;  3OVX A;  3O1G A;  1ATK A;  2P7U A;  3HD3 A;  3N4C A;  2AYN A;  1AU0 A;  2O6X A;  3PW3 A;  4QH6 A;  5F02 A;  5J94 A;  2ACT A;  4N4Z A;  2G7Y A;  2R9M A;  1PBH A;  4MZO A;  2OUL A;  3HHA A;  2F7D A;  3WXF A;  4WA6 A;  1PAD A;  1ZCM A;  1CSB B;  2HXZ A;  1U9Q X;  2CIO A;  1KFX L;  3K9M A;  3IV2 A;  3K8U A;  1SNK A;  3OF8 A;  2DC7 A;  4CDF B;  2B1N A;  2FRA A;  2XU5 A;  3KSE A;  1GCB A;  1PXV A;  2G8E A;  2HH5 A;  3IMA A;  3U8E A;  3KFQ A;  1EWM A;  2DC8 A;  1U9V A;  2NQG A;  1CPJ A;  3WXE A;  1NPZ A;  2DC9 A;  3LXS A;  1DEU A;  4FIP A;  3RVV A;  3DF0 A;  4W5C A;  3MHS A;  3CBJ A;  4YYS A;  1X9Y A;  4DMY A;  4DMX A;  5PAD A;  1AYW A;  4QRG A;  1BQI A;  1QXP A;  4Q8H A;  4ZUX U;  3IOQ A;  1AU4 A;  1EWO A;  1PPP A;  1KFU L;  4BQV A;  6PAD A;  5FPW A;  1CQD A;  1MEM A;  2P0R A;  1AIM A;  1AU2 A;  2B1M A;  4CDD B;  2CB5 A;  1F2B A;  3TNX A;  2R9C A;  2WBF X;  1GEC E;  3K24 A;  4BSQ A;  2E02 A;  1Y4H A;  2DJF B;  1CJL A;  4I04 A;  2IPP B;  1CTE A;  2JQF R;  5CVN B;  4AXM A;  3IHP A;  1GMY A;  1KXR A;  3P5V A;  3USV A;  4MSX A;  4FJC A;  3N3G A;  1S4V A;  1FH0 A;  3KWB X;  3QJ3 A;  2PRE A;  1XKG A;  1YK8 A;  2DCB A;  2BDZ A;  3V6E A;  2FT2 A;  5K16 A;  3MHH A;  3F75 A;  2AUZ A;  2YJ8 A;  3C9E A;  2DZY A;  1NB3 A;  2PAD A;  1MEG A;  2G6D A;  1O0E A;  1U5I A;  3S3R A;  3P5W A;  2DJG B;  1PIP A;  1DF0 A;  2IBI A;  3F5V A;  4RY2 A;  1AU3 A;  4QBB A;  4XR7 A;  1NB5 A;  2AUX A;  3PNR A;  2AIM A;  2P86 A;  1TL9 A;  2R9N A;  2FRQ A;  4W5B A;  3I06 A;  5JH3 A;  1JQP A;  1PPD A;  3LFY A;  1M6D A;  1ME3 A;  2Y6E A;  2PNS A;  4QRX A;  4AXL A;  2XU3 A;  2F1G A;  3BWK A;  1NL6 A;  4YYQ A;  4YVA A;  4CDE B;  3ZUA A;  1MHW A;  1BGO A;  2Y5B A;  2GHU A;  2JQG R;  1QOL A;  3PBH A;  3HWN A;  1GLO A;  2BDL A;  3CBK A;  3GCB A;  4YYV A;  3IEJ A;  2YJ2 A;  4X6J A;  3OF9 A;  3RVW A;  2AVW A;  3OIS A;  4MZS A;  1IWD A;  4QRV A;  5CVM A;  1CB5 A;  3MTN A;  4N79 A;  2YJC A;  3ERV A;  4I05 A;  2VHF A;  1THE A;  2R6N A;  2OP3 A;  2NQA A;  1AEC A;  1STF E;  4N8W A;  1ME4 A;  1TLO A;  5CHT A;  5EF4 A;  3OVZ A;  3QT4 A;  1VJV A;  1MIR A;  3BC3 A;  1ZIV A;  4W4U A;  3KKU A;  2GFO A;  2FYE A;  4YV8 A;  4OEM A;  3NHE A;  1MS6 A;  2DCD A;  4KLB A;  1CV8 A;  2DCC A;  1KHP A;  2DZZ A;  4YYR A;  3CH2 X;  2C0Y A;  2H7J A;  3KW9 A;  3BCN A;  1CS8 A;  2ARY A;  2HD5 A;  2XU1 A;  3AI8 A;  2E03 A;  2YJB A;  4PAD A;  2HHN A;  4BPV A;  1CVZ A;  3D6S A;  4CDC B;  1PCI A;  9PAP A;  1ICF A;  1YAL A;  3KX1 A;  2FUD A;  1A6R A;  4CZW A;  2R9O A;  3QSD A;  4I07 A;  1MDW A;  1F2A A;  1PPN A;  1F29 A;  2DCA A;  3N3K A;  3O0U A;  1PE6 A;  1YVB A;  1U9W A;  1YK7 A;  4BS5 A;  1TU6 A;  2FTD A;  3H7D A;  4HWY A;  2OZ2 A;  2NQD B;  4PP2 E;  4XUI A;  4X6H A;  3H8C A;  2E00 A;  5CHV A;  2R9F A;  4OEL A;  5A24 A;  3MOR A;  2VHS A;  1NQC A;  2YJ9 A;  1U9X A;  1AYU A;  5EGW A;  3KWZ A;  1QMY A;  1KHQ A;  2AS8 A;  3HHI A;  1POP A;  2AYO A;  3RVX A;  1K3B B;  3BOW A;  1BP4 A;  1SP4 B;  4P6G A;  1VSN A;  4Q8G A;  4FK5 A;  2G8J A;  3E1Z B;  1ITO A;  3H8B A;  2FQ9 A;  1F2C A;  1YT7 A;  3H6S A;  1EWL A;  2NQI A;  1Y08 A;  8PCH A;  3BPM A;  2FO5 A;  1NLJ A;  3H89 A;  2XU4 A;  3B79 A;  3CH3 X;  4K7C A;  2AU1 A;  2PBH A;  3P5U A;  3PDF A;  4G54 A;  4P6E A;  4BS6 A;  3V6C A;  1BY8 A;  2ATO A;  4YYU A;  2E01 A;  3I3T A; 
#chains in the Genus database with same CATH topology
 2DC6 A;  4X6I A;  3IUT A;  3PRM A;  1EWP A;  3M99 A;  1Q6K A;  3WXG A;  5JA7 A;  2Z84 A;  7PCK A;  2AGA A;  3BPF A;  1QDQ A;  3IFU A;  4OVZ B;  4PI3 A;  3S3Q A;  1HUC B;  4PP1 A;  1PPO A;  5CVO B;  4BOP A;  3P5X A;  1AYV A;  1EF7 A;  4YYW A;  3OVX A;  3O1G A;  1ATK A;  2P7U A;  3HD3 A;  2BU3 A;  2HWK A;  3N4C A;  2AYN A;  3MP2 A;  1AU0 A;  2O6X A;  3E9S A;  3PW3 A;  4QH6 A;  5F02 A;  5J94 A;  4RNA A;  3RNV A;  2ACT A;  2FE8 A;  4N4Z A;  2G7Y A;  2R9M A;  1PBH A;  3BB7 A;  4MZO A;  2OUL A;  3HHA A;  2F7D A;  3WXF A;  4WA6 A;  1PAD A;  1ZCM A;  1CSB B;  2HXZ A;  1U9Q X;  2CIO A;  1KFX L;  3K9M A;  3IV2 A;  3K8U A;  1SNK A;  3OF8 A;  2DC7 A;  4CDF B;  2B1N A;  2FRA A;  2XU5 A;  3KSE A;  1GCB A;  1PXV A;  2G8E A;  2HH5 A;  3IMA A;  3U8E A;  3KFQ A;  1EWM A;  2DC8 A;  1U9V A;  2NQG A;  1CPJ A;  3WXE A;  1NPZ A;  2DC9 A;  3LXS A;  1DEU A;  4FIP A;  3RVV A;  3DF0 A;  4W5C A;  3MHS A;  3CBJ A;  4YYS A;  1X9Y A;  4DMY A;  4DMX A;  5PAD A;  1AYW A;  4QRG A;  1BQI A;  1QXP A;  4Q8H A;  4IP3 A;  4ZUX U;  3IOQ A;  4BOQ A;  1AU4 A;  2BTW B;  1EWO A;  1PPP A;  1KFU L;  4BQV A;  2DOS A;  5KO3 A;  6PAD A;  5FPW A;  1CQD A;  1MEM A;  2P0R A;  4OW0 A;  1AIM A;  1AU2 A;  2B1M A;  4CDD B;  2CB5 A;  1F2B A;  3TNX A;  2R9C A;  2WBF X;  1GEC E;  3K24 A;  4BSQ A;  2E02 A;  1Y4H A;  4RKX A;  2DJF B;  4GUA A;  1CJL A;  4I04 A;  2IPP B;  4ZTB A;  4MM3 B;  1CTE A;  3PHW A;  3BY4 A;  2JQF R;  5CVN B;  4AXM A;  3IHP A;  1GMY A;  1KXR A;  3P5V A;  3USV A;  4MSX A;  4FJC A;  3PT2 A;  3N3G A;  4MI7 A;  4D8E A;  2JTC A;  1S4V A;  1FH0 A;  3KWB X;  4BOS A;  3QJ3 A;  2PRE A;  1XKG A;  1YK8 A;  2DCB A;  2BDZ A;  3V6E A;  2FT2 A;  5K16 A;  2BTW A;  3F75 A;  3MHH A;  2AUZ A;  2YJ8 A;  3C9E A;  3ZNH A;  2DZY A;  5EZQ A;  1NB3 A;  2PAD A;  1MEG A;  2G6D A;  1O0E A;  1U5I A;  3S3R A;  3P5W A;  2DJG B;  4A5U A;  1PIP A;  1DF0 A;  2IBI A;  3F5V A;  4RY2 A;  3TRK A;  1AU3 A;  4QBB A;  4XR7 A;  1NB5 A;  2AUX A;  3PNR A;  2AIM A;  1UKF A;  2P86 A;  1TL9 A;  2R9N A;  2FRQ A;  4W5B A;  3I06 A;  5JH3 A;  1JQP A;  4OVZ A;  1PPD A;  3LFY A;  1M6D A;  1ME3 A;  2Y6E A;  2PNS A;  3OQC A;  2J7Q A;  4QRX A;  4AXL A;  2XU3 A;  2F1G A;  3BWK A;  1NL6 A;  4YYQ A;  4HXD B;  4YVA A;  4CDE B;  3ZUA A;  1MHW A;  1BGO A;  2Y5B A;  2GHU A;  2JQG R;  1PVJ A;  1QOL A;  3PBH A;  3HWN A;  2J7Q C;  5JZE A;  1GLO A;  2BDL A;  4RF1 A;  3CBK A;  3GCB A;  4YYV A;  3IEJ A;  4P16 A;  2YJ2 A;  4X6J A;  3OF9 A;  3RVW A;  2AVW A;  3OIS A;  4MZS A;  1IWD A;  4QRV A;  5CVM A;  4M0W A;  1CB5 A;  3MTN A;  4N79 A;  5EZS A;  2YJC A;  3ERV A;  4I05 A;  4BOU A;  2VHF A;  1THE A;  3B21 A;  4PT5 A;  2R6N A;  3MJ5 A;  2OP3 A;  2NQA A;  1AEC A;  3PRP A;  1STF E;  4N8W A;  1ME4 A;  1TLO A;  5CHT A;  5EF4 A;  4REZ A;  3OVZ A;  3QT4 A;  1VJV A;  1MIR A;  3BC3 A;  1ZIV A;  4W4U A;  3KKU A;  2GFO A;  2FYE A;  4YV8 A;  4OEM A;  3NHE A;  1MS6 A;  2DCD A;  4KLB A;  1CV8 A;  2DCC A;  4WUR A;  1KHP A;  2DZZ A;  4YYR A;  3CH2 X;  2C0Y A;  2H7J A;  3KW9 A;  3BCN A;  1CS8 A;  2ARY A;  2HD5 A;  2XU1 A;  3AI8 A;  2E03 A;  3W30 A;  2YJB A;  4PAD A;  2JRI A;  2HHN A;  3MTV A;  1CVZ A;  3D6S A;  4BPV A;  4CDC B;  1PCI A;  4D8B A;  9PAP A;  3O65 A;  1ICF A;  1YAL A;  3KX1 A;  2FUD A;  1A6R A;  4CZW A;  2UZJ A;  2R9O A;  3QSD A;  3PHU A;  4I07 A;  1MDW A;  3BBA A;  1F2A A;  1PPN A;  1F29 A;  2DCA A;  3N3K A;  3O0U A;  1PE6 A;  1YVB A;  1U9W A;  1YK7 A;  4BS5 A;  1TU6 A;  2FTD A;  3H7D A;  4IUM A;  4HWY A;  2OZ2 A;  2NQD B;  4PP2 E;  4XUI A;  4X6H A;  5E6J A;  3H8C A;  2E00 A;  5CHV A;  2R9F A;  4OEL A;  5A24 A;  3MOR A;  2VHS A;  1NQC A;  1YZB A;  2YJ9 A;  1DKI A;  1U9X A;  1AYU A;  4BOZ A;  3W31 A;  4D8I A;  5EGW A;  3KWZ A;  1QMY A;  1KHQ A;  2AS8 A;  3HHI A;  1POP A;  2AYO A;  3RVX A;  1K3B B;  3BOW A;  1BP4 A;  1SP4 B;  4P6G A;  1VSN A;  4Q8G A;  4R3D A;  4FK5 A;  2G8J A;  3E1Z B;  1ITO A;  3H8B A;  2FQ9 A;  1F2C A;  1YT7 A;  3H6S A;  1EWL A;  2NQI A;  1Y08 A;  3C0R A;  8PCH A;  3BPM A;  2FO5 A;  4RF0 A;  1NLJ A;  3H89 A;  2XU4 A;  3B79 A;  3CH3 X;  4K7C A;  2AU1 A;  2PBH A;  3P5U A;  4XZX A;  3PDF A;  4G54 A;  3PHX A;  4P6E A;  4BS6 A;  3V6C A;  1BY8 A;  3TMP A;  3PSE A;  2ATO A;  4YYU A;  2E01 A;  3I3T A; 
#chains in the Genus database with same CATH homology
 2DC6 A;  4X6I A;  3IUT A;  1EWP A;  3M99 A;  1Q6K A;  3WXG A;  5JA7 A;  7PCK A;  3BPF A;  1QDQ A;  4PI3 A;  3S3Q A;  1HUC B;  4PP1 A;  1PPO A;  5CVO B;  3P5X A;  1AYV A;  1EF7 A;  4YYW A;  3OVX A;  3O1G A;  1ATK A;  2P7U A;  1W5R A;  1E2T A;  3HD3 A;  3N4C A;  2AYN A;  1AU0 A;  2O6X A;  3PW3 A;  4QH6 A;  5F02 A;  5J94 A;  2ACT A;  4N4Z A;  2G7Y A;  2R9M A;  1PBH A;  4MZO A;  1W6F A;  2OUL A;  3HHA A;  4BGF A;  2F7D A;  3WXF A;  4WA6 A;  1PAD A;  1ZCM A;  1CSB B;  2HXZ A;  1U9Q X;  2CIO A;  4NV7 A;  1KFX L;  3K9M A;  3IV2 A;  3K8U A;  1SNK A;  3OF8 A;  2DC7 A;  4CDF B;  2B1N A;  2FRA A;  2XU5 A;  3KSE A;  1GCB A;  1PXV A;  2G8E A;  2HH5 A;  3IMA A;  3U8E A;  3KFQ A;  1EWM A;  2DC8 A;  1U9V A;  2NQG A;  1CPJ A;  3WXE A;  1NPZ A;  2DC9 A;  3LXS A;  1DEU A;  4FIP A;  3RVV A;  3DF0 A;  4W5C A;  3MHS A;  3CBJ A;  4YYS A;  1X9Y A;  4DMY A;  4DMX A;  5PAD A;  1AYW A;  4QRG A;  1BQI A;  1QXP A;  4Q8H A;  4ZUX U;  3IOQ A;  1AU4 A;  1EWO A;  2BSZ A;  1PPP A;  1KFU L;  4BQV A;  6PAD A;  5FPW A;  1CQD A;  1MEM A;  2P0R A;  1AIM A;  1AU2 A;  2B1M A;  4CDD B;  2CB5 A;  1F2B A;  1GX3 A;  3TNX A;  2R9C A;  2WBF X;  1GEC E;  3K24 A;  4BSQ A;  2E02 A;  1Y4H A;  2DJF B;  1CJL A;  4I04 A;  2IPP B;  1CTE A;  2JQF R;  5CVN B;  4AXM A;  3IHP A;  1GMY A;  1KXR A;  3P5V A;  3USV A;  4C5P A;  2VFB A;  4MSX A;  4FJC A;  3N3G A;  1S4V A;  1FH0 A;  3KWB X;  3QJ3 A;  2PRE A;  1XKG A;  1YK8 A;  2DCB A;  2BDZ A;  3V6E A;  2FT2 A;  5K16 A;  3MHH A;  3F75 A;  2AUZ A;  2YJ8 A;  3C9E A;  2DZY A;  1NB3 A;  2PAD A;  1MEG A;  2G6D A;  1O0E A;  1U5I A;  3S3R A;  3P5W A;  2DJG B;  2VFC A;  1PIP A;  1DF0 A;  2IBI A;  3F5V A;  4RY2 A;  1AU3 A;  4QBB A;  4XR7 A;  1NB5 A;  2AUX A;  3PNR A;  2AIM A;  2P86 A;  1TL9 A;  2R9N A;  2FRQ A;  4W5B A;  3I06 A;  5JH3 A;  1JQP A;  1PPD A;  3LFY A;  1M6D A;  1ME3 A;  2Y6E A;  2PNS A;  3D9W A;  4QRX A;  4AXL A;  2XU3 A;  2F1G A;  3BWK A;  1NL6 A;  4YYQ A;  4YVA A;  4CDE B;  3ZUA A;  1MHW A;  1BGO A;  2Y5B A;  2GHU A;  2JQG R;  1QOL A;  3PBH A;  3HWN A;  1GLO A;  2BDL A;  3CBK A;  3GCB A;  4YYV A;  3IEJ A;  2YJ2 A;  4X6J A;  3OF9 A;  3RVW A;  2AVW A;  3OIS A;  4MZS A;  1IWD A;  4QRV A;  5CVM A;  1CB5 A;  3MTN A;  4N79 A;  2YJC A;  3ERV A;  4I05 A;  2VHF A;  1THE A;  2R6N A;  2OP3 A;  2NQA A;  1AEC A;  1STF E;  4N8W A;  1ME4 A;  1TLO A;  5CHT A;  5EF4 A;  3OVZ A;  3QT4 A;  1VJV A;  1MIR A;  3BC3 A;  1W4T A;  1ZIV A;  4W4U A;  3KKU A;  2GFO A;  2FYE A;  4YV8 A;  4OEM A;  3NHE A;  1MS6 A;  2DCD A;  4KLB A;  1CV8 A;  2DCC A;  1KHP A;  2DZZ A;  4YYR A;  3CH2 X;  2C0Y A;  2H7J A;  3KW9 A;  3BCN A;  1CS8 A;  2ARY A;  2HD5 A;  2XU1 A;  3AI8 A;  2E03 A;  2YJB A;  4PAD A;  2HHN A;  4BPV A;  1CVZ A;  3D6S A;  4CDC B;  1PCI A;  9PAP A;  1ICF A;  1YAL A;  3KX1 A;  2FUD A;  1A6R A;  4CZW A;  2R9O A;  3QSD A;  4B55 A;  4I07 A;  1MDW A;  1F2A A;  1PPN A;  1F29 A;  2DCA A;  3N3K A;  3O0U A;  1PE6 A;  1YVB A;  1U9W A;  1YK7 A;  4BS5 A;  1TU6 A;  2FTD A;  3H7D A;  4HWY A;  2OZ2 A;  2NQD B;  4NV8 A;  4PP2 E;  4XUI A;  4X6H A;  3H8C A;  2E00 A;  5CHV A;  2R9F A;  4OEL A;  5A24 A;  3MOR A;  2VHS A;  1NQC A;  2YJ9 A;  1U9X A;  1AYU A;  5EGW A;  3KWZ A;  1QMY A;  1KHQ A;  2AS8 A;  3HHI A;  1POP A;  2AYO A;  3RVX A;  1K3B B;  3BOW A;  1BP4 A;  1SP4 B;  4P6G A;  1VSN A;  4Q8G A;  4FK5 A;  2G8J A;  3E1Z B;  1ITO A;  3H8B A;  2FQ9 A;  1F2C A;  1YT7 A;  3H6S A;  1EWL A;  2NQI A;  1Y08 A;  8PCH A;  3BPM A;  2FO5 A;  1NLJ A;  3H89 A;  2XU4 A;  3B79 A;  3CH3 X;  4K7C A;  2AU1 A;  2PBH A;  3P5U A;  3PDF A;  4G54 A;  4P6E A;  4BS6 A;  4GUZ A;  3V6C A;  1BY8 A;  2ATO A;  4YYU A;  2E01 A;  3I3T A;  3LTW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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