3BWKA

Crystal structure of falcipain-3 with its inhibitor, k11017
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
242
structure length
242
Chain Sequence
YEANYEDVIKKYKPADAKLDRIAYDWRLHGGVTPVKDQALCGSCWAFSSVGSVESQYAIRKKALFLFSEQELVDCSVKNNGCYGGYITNAFDDMIDLGGLCSQDDYPYVSNLPETCNLKRCNERYTIKSYVSIPDDKFKEALRYLGPISISIAASDDFAFYRGGFYDGECGAAPNHAVILVGYGMKDIYNEDTGRMEKFYYYIIKNSWGSDWGEGGYINLETDENGYKKTCSIGTEAYVPLL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Vinyl sulfones as antiparasitic agents and a structural basis for drug design.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Cysteine protease falcipain-3
total genus 69
structure length 242
sequence length 242
chains with identical sequence B, C, D
ec nomenclature ec 3.4.22.-:
pdb deposition date 2008-01-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 3bwkA00
3CH2X 2E03A 1M6DA 1A6RA 1YALA 1NPZA 2B1NA 2H7JA 2AUZA 3H7DA 4MZOA 1AU3A 1ATKA 1S4VA 3KFQA 2AS8A 5EGWA 4ZUXU 1MEGA 4N4ZA 3N4CA 4QBBA 1BQIA 4W5CA 3LFYA 2FTDA 1CB5A 5FPWA 2ATOA 2OP3A 1GCBA 1K3BB 1YK8A 4YYWA 1TL9A 3O0UA 1DEUA 2XU4A 1ZIVA 2P7UA 2HD5A 7PCKA 1MDWA 1AU4A 1MEMA 3MHSA 2OULA 3BC3A 2R9OA 5CHTA 3P5WA 4RY2A 2R9FA 2PADA 2FQ9A 1ZCMA 3K24A 1ICFA 2C0YA 2FT2A 4X6IA 3WXFA 1QMYA 3MTNA 1POPA 2O6XA 2R9MA 2R9CA 2XU1A 1F2BA 1MIRA 1PPPA 2FRQA 1BP4A 1FH0A 3O1GA 1PXVA 3V6CA 4G54A 3N3KA 1HUCB 1BY8A 4DMYA 3BOWA 1PE6A 3D6SA 3S3QA 4QRGA 1TLOA 3P5VA 5K16A 2XU5A 2GHUA 1VJVA 3U8EA 1EWLA 3P5UA 4YYVA 4I04A 1U9WA 1F2AA 2GFOA 2DCDA 2AU1A 2FUDA 4W5BA 1AECA 3CBJA 1PCIA 2AYOA 3AI8A 1YT7A 4MSXA 1EWPA 4WA6A 1CV8A 3KWBX 3RVWA 3H6SA 1PPDA 3MORA 1QXPA 4X6HA 3QSDA 2DCAA 1X9YA 2FRAA 4XR7A 2DC6A 1SP4B 1THEA 4CDEB 4BSQA 1U9VA 3H8BA 1PBHA 3F5VA 3RVVA 5EF4A 2Y6EA 3PBHA 4N79A 1GMYA 1YVBA 2HXZA 3K9MA 5PADA 2NQAA 1NB3A 2E02A 4Q8GA 3CBKA 1CS8A 5CHVA 3WXEA 3CH3X 2VHSA 4K7CA 4FJCA 3NHEA 2DJFB 4PP2E 4CDFB 2AVWA 3HD3A 3ERVA 1TU6A 4N8WA 4BQVA 1NQCA 8PCHA 1EWOA 3WXGA 3KX1A 4HWYA 3PNRA 4YYRA 1PADA 1CJLA 1CSBB 2YJ2A 1GECE 1CTEA 1XKGA 2YJCA 3IV2A 4OELA 4BS6A 5J94A 3DF0A 3PW3A 2HHNA 1YK7A 3OISA 2OZ2A 2E00A 1QOLA 2DCCA 4BPVA 2F7DA 4P6GA 3KSEA 1NB5A 1CVZA 2DC7A 9PAPA 1PPOA 5CVMA 1JQPA 2P0RA 4YYUA 2R6NA 2G6DA 3B79A 3MHHA 1KHPA 2CIOA 3BCNA 2DZZA 1VSNA 1AU0A 1AYVA 1EWMA 1GLOA 1Y08A 2F1GA 5CVNB 1AIMA 1SNKA 5JA7A 2YJBA 2G8JA 1PPNA 4QRVA 3BWKA 3OVXA 3H8CA 1AYWA 1ME3A 4QRXA 3HHAA 2ARYA 3C9EA 1U9XA 3M99A 1BGOA 2HH5A 4P6EA 6PADA 3PDFA 4YVAA 2B1MA 4YYQA 5A24A 2AUXA 3S3RA 3OVZA 2FYEA 4BS5A 2AYNA 3K8UA 1STFE 2JQFR 3KKUA 2DCBA 1IWDA 4KLBA 2JQGR 2FO5A 2CB5A 2NQGA 2G8EA 2DC9A 2NQIA 4CDDB 5CVOB 2DJGB 1MHWA 2Y5BA 3BPMA 2IPPB 2NQDB 4W4UA 1ITOA 1Y4HA 3RVXA 4AXMA 1ME4A 2AIMA 4Q8HA 4QH6A 3IEJA 3TNXA 4PP1A 5F02A 1DF0A 2YJ8A 1AYUA 3IMAA 3F75A 2PREA 4I07A 3ZUAA 4CZWA 4FIPA 2ACTA 2IBIA 3KW9A 1PIPA 1U9QX 3I3TA 3GCBA 2VHFA 3HWNA 2PNSA 4OEMA 1O0EA 3BPFA 3USVA 3LXSA 4X6JA 1CQDA 2G7YA 3H89A 2P86A 1QDQA 3N3GA 3OF8A 1F29A 3QJ3A 3I06A 3P5XA 1EF7A 1F2CA 4YV8A 4FK5A 1CPJA 3E1ZB 4I05A 3HHIA 2PBHA 1NL6A 2DC8A 2BDLA 4YYSA 1AU2A 2DZYA 3KWZA 4XUIA 3IHPA 5JH3A 1KXRA 3IOQA 1NLJA 4PI3A 3V6EA 2R9NA 2BDZA 3IUTA 4AXLA 2WBFX 1KFUL 4DMXA 2XU3A 1KFXL 1U5IA 3OF9A 4CDCB 2E01A 2YJ9A 1MS6A 1KHQA 4PADA 3QT4A 4MZSA 1Q6KA
chains in the Genus database with same CATH superfamily
3CH2X 2E03A 1M6DA 1A6RA 1YALA 1NPZA 2B1NA 3ZNHA 2H7JA 2AUZA 3H7DA 4MZOA 1AU3A 1ATKA 1S4VA 3KFQA 3BBAA 2AS8A 2Z84A 5EGWA 4ZUXU 1MEGA 2FE8A 4N4ZA 3N4CA 4QBBA 1BQIA 2BTWB 3LFYA 4W5CA 2FTDA 1CB5A 5FPWA 2ATOA 2OP3A 3PRMA 1GCBA 1K3BB 1YK8A 4YYWA 1TL9A 3O0UA 3OQCA 1DEUA 2XU4A 1ZIVA 2P7UA 2BTWA 2HD5A 7PCKA 1MDWA 1AU4A 1MEMA 2DOSA 3MHSA 2OULA 3BC3A 2R9OA 4WURA 5CHTA 3P5WA 4RY2A 2R9FA 2PADA 2FQ9A 1ZCMA 3K24A 1ICFA 2C0YA 2FT2A 4X6IA 3WXFA 1QMYA 3MTNA 1POPA 2O6XA 2R9MA 2R9CA 2XU1A 1F2BA 1MIRA 1PPPA 2FRQA 1BP4A 1FH0A 3O1GA 1PXVA 3V6CA 4G54A 4D8BA 3N3KA 1HUCB 1BY8A 4DMYA 2JTCA 3BOWA 1PE6A 3D6SA 3S3QA 4QRGA 1TLOA 3P5VA 5K16A 2XU5A 2GHUA 1VJVA 3U8EA 4P16A 1EWLA 3P5UA 4YYVA 3E9SA 3W31A 4I04A 3C0RA 1U9WA 1F2AA 2GFOA 4RF0A 2DCDA 2AU1A 1DKIA 2FUDA 4W5BA 1AECA 3CBJA 1PCIA 2AYOA 3RNVA 3AI8A 1YT7A 4MSXA 1EWPA 3O65A 4WA6A 1CV8A 3KWBX 3RVWA 3H6SA 1PPDA 3MORA 1QXPA 4X6HA 3QSDA 4XZXA 2DCAA 1X9YA 2FRAA 4XR7A 2DC6A 1SP4B 1THEA 4CDEB 4BSQA 1U9VA 3H8BA 1PBHA 3F5VA 2BU3A 3PHUA 3RVVA 5EF4A 2Y6EA 4BOUA 3PBHA 4N79A 1GMYA 1YVBA 2HXZA 3K9MA 5PADA 2NQAA 1NB3A 2E02A 4Q8GA 3CBKA 1CS8A 5CHVA 3WXEA 3CH3X 2VHSA 4K7CA 4FJCA 3TRKA 3NHEA 2DJFB 4PP2E 4CDFB 2AVWA 3HD3A 4BOPA 3ERVA 1TU6A 4N8WA 4BQVA 1NQCA 8PCHA 2HWKA 1EWOA 3WXGA 3KX1A 3BY4A 3MTVA 4HWYA 3PNRA 4OW0A 4YYRA 1PADA 1CJLA 1CSBB 2J7QC 2YJ2A 1GECE 3PHWA 1CTEA 1XKGA 4BOZA 2YJCA 3IV2A 4OELA 4BS6A 5J94A 3DF0A 3PW3A 2HHNA 1YK7A 3OISA 2OZ2A 2E00A 1QOLA 2DCCA 5EZQA 4BPVA 2F7DA 4P6GA 4M0WA 3KSEA 1NB5A 1CVZA 2DC7A 9PAPA 1PPOA 5CVMA 1JQPA 3MP2A 4R3DA 2AGAA 2P0RA 4YYUA 2R6NA 2G6DA 3B79A 5JZEA 3MHHA 1KHPA 3W30A 2CIOA 3BCNA 2DZZA 1VSNA 1AU0A 1AYVA 1EWMA 1GLOA 4MI7A 1Y08A 2F1GA 5CVNB 1AIMA 1SNKA 5JA7A 2YJBA 2G8JA 1PPNA 4QRVA 3BWKA 3OVXA 3H8CA 1AYWA 1ME3A 4QRXA 3HHAA 2ARYA 2J7QA 3C9EA 1U9XA 3M99A 4RKXA 1BGOA 2HH5A 4P6EA 6PADA 4RNAA 3PDFA 4YVAA 2B1MA 4PT5A 4YYQA 5A24A 2AUXA 3S3RA 3OVZA 2FYEA 4BS5A 2AYNA 3K8UA 4REZA 4MM3B 1STFE 2JQFR 3KKUA 2DCBA 1IWDA 5E6JA 3PSEA 4KLBA 2JQGR 2FO5A 3PT2A 4OVZB 2CB5A 2NQGA 2JRIA 2G8EA 2DC9A 2NQIA 4CDDB 5CVOB 2DJGB 1MHWA 2Y5BA 3BPMA 2IPPB 3MJ5A 2NQDB 3BB7A 4W4UA 1ITOA 1Y4HA 3RVXA 4AXMA 1ME4A 2AIMA 1UKFA 4Q8HA 4QH6A 3IEJA 4OVZA 3TNXA 4PP1A 5F02A 1DF0A 2YJ8A 1AYUA 3IMAA 3F75A 2PREA 4I07A 3ZUAA 4CZWA 4FIPA 2ACTA 2IBIA 3KW9A 1PIPA 1U9QX 3PRPA 4D8EA 3I3TA 3GCBA 2VHFA 3HWNA 2PNSA 4A5UA 4OEMA 1O0EA 3BPFA 3USVA 3LXSA 4X6JA 1CQDA 2G7YA 3H89A 2P86A 1QDQA 3N3GA 3OF8A 1F29A 3QJ3A 3I06A 4BOQA 3P5XA 1EF7A 1F2CA 4YV8A 4FK5A 1CPJA 5EZSA 4GUAA 3E1ZB 4I05A 3HHIA 2PBHA 1NL6A 4D8IA 2DC8A 2BDLA 4YYSA 1AU2A 2UZJA 2DZYA 3KWZA 4IP3A 4XUIA 4ZTBA 3IHPA 5JH3A 1KXRA 1PVJA 3IOQA 1NLJA 4PI3A 3V6EA 2R9NA 2BDZA 3IUTA 4AXLA 2WBFX 4IUMA 1KFUL 3IFUA 3PHXA 4DMXA 3B21A 4HXDB 4RF1A 2XU3A 1KFXL 3TMPA 5KO3A 1U5IA 3OF9A 4CDCB 2E01A 2YJ9A 1MS6A 1KHQA 4PADA 3QT4A 4BOSA 1YZBA 4MZSA 1Q6KA
chains in the Genus database with same CATH topology
3CH2X 2E03A 1M6DA 1A6RA 1YALA 1NPZA 2B1NA 2H7JA 2AUZA 3H7DA 4MZOA 1AU3A 1ATKA 1S4VA 3KFQA 2AS8A 5EGWA 4ZUXU 1MEGA 4N4ZA 3N4CA 4QBBA 1BQIA 4W5CA 3LFYA 2FTDA 1CB5A 4NV8A 5FPWA 2ATOA 2OP3A 1GCBA 1K3BB 1YK8A 4YYWA 1TL9A 3O0UA 1DEUA 2XU4A 1ZIVA 2P7UA 2HD5A 7PCKA 1MDWA 1AU4A 1MEMA 3MHSA 2OULA 3BC3A 2R9OA 2BSZA 5CHTA 3P5WA 4RY2A 2R9FA 2PADA 2FQ9A 1ZCMA 3K24A 1ICFA 2C0YA 2FT2A 4X6IA 3WXFA 1QMYA 3MTNA 1POPA 1W5RA 2O6XA 2R9MA 2R9CA 2XU1A 1F2BA 1MIRA 1PPPA 4B55A 2FRQA 1BP4A 1FH0A 3O1GA 1PXVA 3V6CA 4G54A 3N3KA 1HUCB 1BY8A 4DMYA 3BOWA 1PE6A 3D6SA 3S3QA 4QRGA 1TLOA 3P5VA 5K16A 2XU5A 2GHUA 3D9WA 1VJVA 3U8EA 1EWLA 3P5UA 4YYVA 4I04A 1U9WA 1F2AA 2GFOA 2DCDA 2AU1A 2FUDA 4W5BA 1AECA 3CBJA 1PCIA 2AYOA 3AI8A 1YT7A 4MSXA 1EWPA 4WA6A 1CV8A 3KWBX 3RVWA 3H6SA 1PPDA 1E2TA 3MORA 1QXPA 4X6HA 3QSDA 2DCAA 1X9YA 2FRAA 4XR7A 2DC6A 1SP4B 1THEA 4CDEB 4BSQA 1U9VA 3H8BA 1PBHA 3F5VA 3RVVA 5EF4A 4NV7A 2Y6EA 3PBHA 4N79A 1GMYA 1YVBA 2HXZA 3K9MA 5PADA 2NQAA 1NB3A 2E02A 4Q8GA 3CBKA 1CS8A 5CHVA 3WXEA 3CH3X 2VHSA 4K7CA 4FJCA 3NHEA 2DJFB 4PP2E 4CDFB 2AVWA 3HD3A 3ERVA 1TU6A 4N8WA 4BQVA 1NQCA 8PCHA 1EWOA 3WXGA 3KX1A 4HWYA 3PNRA 4YYRA 1PADA 1CJLA 1CSBB 2YJ2A 1GECE 1CTEA 1XKGA 2YJCA 3IV2A 4OELA 4BS6A 5J94A 3DF0A 3PW3A 2HHNA 1YK7A 3OISA 2OZ2A 2E00A 1QOLA 2DCCA 4BPVA 2F7DA 4P6GA 3KSEA 1NB5A 1CVZA 2DC7A 9PAPA 1PPOA 5CVMA 1JQPA 1W4TA 2P0RA 4YYUA 2R6NA 2G6DA 3B79A 3MHHA 1KHPA 2CIOA 3BCNA 2DZZA 1VSNA 1AU0A 1AYVA 1EWMA 1GLOA 1Y08A 2F1GA 5CVNB 1AIMA 1SNKA 5JA7A 2VFBA 2YJBA 2G8JA 1PPNA 4QRVA 3BWKA 3OVXA 2VFCA 3H8CA 1AYWA 1ME3A 4QRXA 3HHAA 4BGFA 2ARYA 3C9EA 1U9XA 3M99A 1BGOA 2HH5A 4P6EA 6PADA 3PDFA 4YVAA 2B1MA 1GX3A 4YYQA 5A24A 2AUXA 3S3RA 3OVZA 2FYEA 4BS5A 2AYNA 3K8UA 1STFE 2JQFR 3KKUA 2DCBA 1IWDA 4KLBA 2JQGR 2FO5A 2CB5A 2NQGA 2G8EA 2DC9A 2NQIA 4CDDB 5CVOB 2DJGB 1MHWA 2Y5BA 3BPMA 2IPPB 2NQDB 4W4UA 1ITOA 1Y4HA 3RVXA 4AXMA 1ME4A 2AIMA 4Q8HA 4QH6A 3IEJA 1W6FA 4PP1A 3TNXA 5F02A 1DF0A 2YJ8A 3LTWA 1AYUA 3IMAA 3F75A 2PREA 4I07A 3ZUAA 4CZWA 4FIPA 2ACTA 2IBIA 3KW9A 1PIPA 1U9QX 4C5PA 3I3TA 3GCBA 2VHFA 3HWNA 2PNSA 4OEMA 1O0EA 3BPFA 3USVA 3LXSA 4X6JA 1CQDA 2G7YA 3H89A 2P86A 1QDQA 3N3GA 3OF8A 1F29A 3QJ3A 3I06A 3P5XA 1EF7A 1F2CA 4YV8A 4FK5A 1CPJA 3E1ZB 4I05A 3HHIA 2PBHA 1NL6A 2DC8A 2BDLA 4YYSA 1AU2A 2DZYA 3KWZA 4XUIA 3IHPA 5JH3A 4GUZA 1KXRA 3IOQA 1NLJA 4PI3A 3V6EA 2R9NA 2BDZA 3IUTA 4AXLA 2WBFX 1KFUL 4DMXA 2XU3A 1KFXL 1U5IA 3OF9A 4CDCB 2E01A 2YJ9A 1MS6A 1KHQA 4PADA 3QT4A 4MZSA 1Q6KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CH2 X;  2E03 A;  1M6D A;  1A6R A;  1YAL A;  1NPZ A;  2B1N A;  2H7J A;  2AUZ A;  3H7D A;  4MZO A;  1AU3 A;  1ATK A;  1S4V A;  3KFQ A;  2AS8 A;  5EGW A;  4ZUX U;  1MEG A;  4N4Z A;  3N4C A;  4QBB A;  1BQI A;  4W5C A;  3LFY A;  2FTD A;  1CB5 A;  5FPW A;  2ATO A;  2OP3 A;  1GCB A;  1K3B B;  1YK8 A;  4YYW A;  1TL9 A;  3O0U A;  1DEU A;  2XU4 A;  1ZIV A;  2P7U A;  2HD5 A;  7PCK A;  1MDW A;  1AU4 A;  1MEM A;  3MHS A;  2OUL A;  3BC3 A;  2R9O A;  5CHT A;  3P5W A;  4RY2 A;  2R9F A;  2PAD A;  2FQ9 A;  1ZCM A;  3K24 A;  1ICF A;  2C0Y A;  2FT2 A;  4X6I A;  3WXF A;  1QMY A;  3MTN A;  1POP A;  2O6X A;  2R9M A;  2R9C A;  2XU1 A;  1F2B A;  1MIR A;  1PPP A;  2FRQ A;  1BP4 A;  1FH0 A;  3O1G A;  1PXV A;  3V6C A;  4G54 A;  3N3K A;  1HUC B;  1BY8 A;  4DMY A;  3BOW A;  1PE6 A;  3D6S A;  3S3Q A;  4QRG A;  1TLO A;  3P5V A;  5K16 A;  2XU5 A;  2GHU A;  1VJV A;  3U8E A;  1EWL A;  3P5U A;  4YYV A;  4I04 A;  1U9W A;  1F2A A;  2GFO A;  2DCD A;  2AU1 A;  2FUD A;  4W5B A;  1AEC A;  3CBJ A;  1PCI A;  2AYO A;  3AI8 A;  1YT7 A;  4MSX A;  1EWP A;  4WA6 A;  1CV8 A;  3KWB X;  3RVW A;  3H6S A;  1PPD A;  3MOR A;  1QXP A;  4X6H A;  3QSD A;  2DCA A;  1X9Y A;  2FRA A;  4XR7 A;  2DC6 A;  1SP4 B;  1THE A;  4CDE B;  4BSQ A;  1U9V A;  3H8B A;  1PBH A;  3F5V A;  3RVV A;  5EF4 A;  2Y6E A;  3PBH A;  4N79 A;  1GMY A;  1YVB A;  2HXZ A;  3K9M A;  5PAD A;  2NQA A;  1NB3 A;  2E02 A;  4Q8G A;  3CBK A;  1CS8 A;  5CHV A;  3WXE A;  3CH3 X;  2VHS A;  4K7C A;  4FJC A;  3NHE A;  2DJF B;  4PP2 E;  4CDF B;  2AVW A;  3HD3 A;  3ERV A;  1TU6 A;  4N8W A;  4BQV A;  1NQC A;  8PCH A;  1EWO A;  3WXG A;  3KX1 A;  4HWY A;  3PNR A;  4YYR A;  1PAD A;  1CJL A;  1CSB B;  2YJ2 A;  1GEC E;  1CTE A;  1XKG A;  2YJC A;  3IV2 A;  4OEL A;  4BS6 A;  5J94 A;  3DF0 A;  3PW3 A;  2HHN A;  1YK7 A;  3OIS A;  2OZ2 A;  2E00 A;  1QOL A;  2DCC A;  4BPV A;  2F7D A;  4P6G A;  3KSE A;  1NB5 A;  1CVZ A;  2DC7 A;  9PAP A;  1PPO A;  5CVM A;  1JQP A;  2P0R A;  4YYU A;  2R6N A;  2G6D A;  3B79 A;  3MHH A;  1KHP A;  2CIO A;  3BCN A;  2DZZ A;  1VSN A;  1AU0 A;  1AYV A;  1EWM A;  1GLO A;  1Y08 A;  2F1G A;  5CVN B;  1AIM A;  1SNK A;  5JA7 A;  2YJB A;  2G8J A;  1PPN A;  4QRV A;  3BWK A;  3OVX A;  3H8C A;  1AYW A;  1ME3 A;  4QRX A;  3HHA A;  2ARY A;  3C9E A;  1U9X A;  3M99 A;  1BGO A;  2HH5 A;  4P6E A;  6PAD A;  3PDF A;  4YVA A;  2B1M A;  4YYQ A;  5A24 A;  2AUX A;  3S3R A;  3OVZ A;  2FYE A;  4BS5 A;  2AYN A;  3K8U A;  1STF E;  2JQF R;  3KKU A;  2DCB A;  1IWD A;  4KLB A;  2JQG R;  2FO5 A;  2CB5 A;  2NQG A;  2G8E A;  2DC9 A;  2NQI A;  4CDD B;  5CVO B;  2DJG B;  1MHW A;  2Y5B A;  3BPM A;  2IPP B;  2NQD B;  4W4U A;  1ITO A;  1Y4H A;  3RVX A;  4AXM A;  1ME4 A;  2AIM A;  4Q8H A;  4QH6 A;  3IEJ A;  3TNX A;  4PP1 A;  5F02 A;  1DF0 A;  2YJ8 A;  1AYU A;  3IMA A;  3F75 A;  2PRE A;  4I07 A;  3ZUA A;  4CZW A;  4FIP A;  2ACT A;  2IBI A;  3KW9 A;  1PIP A;  1U9Q X;  3I3T A;  3GCB A;  2VHF A;  3HWN A;  2PNS A;  4OEM A;  1O0E A;  3BPF A;  3USV A;  3LXS A;  4X6J A;  1CQD A;  2G7Y A;  3H89 A;  2P86 A;  1QDQ A;  3N3G A;  3OF8 A;  1F29 A;  3QJ3 A;  3I06 A;  3P5X A;  1EF7 A;  1F2C A;  4YV8 A;  4FK5 A;  1CPJ A;  3E1Z B;  4I05 A;  3HHI A;  2PBH A;  1NL6 A;  2DC8 A;  2BDL A;  4YYS A;  1AU2 A;  2DZY A;  3KWZ A;  4XUI A;  3IHP A;  5JH3 A;  1KXR A;  3IOQ A;  1NLJ A;  4PI3 A;  3V6E A;  2R9N A;  2BDZ A;  3IUT A;  4AXL A;  2WBF X;  1KFU L;  4DMX A;  2XU3 A;  1KFX L;  1U5I A;  3OF9 A;  4CDC B;  2E01 A;  2YJ9 A;  1MS6 A;  1KHQ A;  4PAD A;  3QT4 A;  4MZS A;  1Q6K A; 
#chains in the Genus database with same CATH topology
 3CH2 X;  2E03 A;  1M6D A;  1A6R A;  1YAL A;  1NPZ A;  2B1N A;  3ZNH A;  2H7J A;  2AUZ A;  3H7D A;  4MZO A;  1AU3 A;  1ATK A;  1S4V A;  3KFQ A;  3BBA A;  2AS8 A;  2Z84 A;  5EGW A;  4ZUX U;  1MEG A;  2FE8 A;  4N4Z A;  3N4C A;  4QBB A;  1BQI A;  2BTW B;  3LFY A;  4W5C A;  2FTD A;  1CB5 A;  5FPW A;  2ATO A;  2OP3 A;  3PRM A;  1GCB A;  1K3B B;  1YK8 A;  4YYW A;  1TL9 A;  3O0U A;  3OQC A;  1DEU A;  2XU4 A;  1ZIV A;  2P7U A;  2BTW A;  2HD5 A;  7PCK A;  1MDW A;  1AU4 A;  1MEM A;  2DOS A;  3MHS A;  2OUL A;  3BC3 A;  2R9O A;  4WUR A;  5CHT A;  3P5W A;  4RY2 A;  2R9F A;  2PAD A;  2FQ9 A;  1ZCM A;  3K24 A;  1ICF A;  2C0Y A;  2FT2 A;  4X6I A;  3WXF A;  1QMY A;  3MTN A;  1POP A;  2O6X A;  2R9M A;  2R9C A;  2XU1 A;  1F2B A;  1MIR A;  1PPP A;  2FRQ A;  1BP4 A;  1FH0 A;  3O1G A;  1PXV A;  3V6C A;  4G54 A;  4D8B A;  3N3K A;  1HUC B;  1BY8 A;  4DMY A;  2JTC A;  3BOW A;  1PE6 A;  3D6S A;  3S3Q A;  4QRG A;  1TLO A;  3P5V A;  5K16 A;  2XU5 A;  2GHU A;  1VJV A;  3U8E A;  4P16 A;  1EWL A;  3P5U A;  4YYV A;  3E9S A;  3W31 A;  4I04 A;  3C0R A;  1U9W A;  1F2A A;  2GFO A;  4RF0 A;  2DCD A;  2AU1 A;  1DKI A;  2FUD A;  4W5B A;  1AEC A;  3CBJ A;  1PCI A;  2AYO A;  3RNV A;  3AI8 A;  1YT7 A;  4MSX A;  1EWP A;  3O65 A;  4WA6 A;  1CV8 A;  3KWB X;  3RVW A;  3H6S A;  1PPD A;  3MOR A;  1QXP A;  4X6H A;  3QSD A;  4XZX A;  2DCA A;  1X9Y A;  2FRA A;  4XR7 A;  2DC6 A;  1SP4 B;  1THE A;  4CDE B;  4BSQ A;  1U9V A;  3H8B A;  1PBH A;  3F5V A;  2BU3 A;  3PHU A;  3RVV A;  5EF4 A;  2Y6E A;  4BOU A;  3PBH A;  4N79 A;  1GMY A;  1YVB A;  2HXZ A;  3K9M A;  5PAD A;  2NQA A;  1NB3 A;  2E02 A;  4Q8G A;  3CBK A;  1CS8 A;  5CHV A;  3WXE A;  3CH3 X;  2VHS A;  4K7C A;  4FJC A;  3TRK A;  3NHE A;  2DJF B;  4PP2 E;  4CDF B;  2AVW A;  3HD3 A;  4BOP A;  3ERV A;  1TU6 A;  4N8W A;  4BQV A;  1NQC A;  8PCH A;  2HWK A;  1EWO A;  3WXG A;  3KX1 A;  3BY4 A;  3MTV A;  4HWY A;  3PNR A;  4OW0 A;  4YYR A;  1PAD A;  1CJL A;  1CSB B;  2J7Q C;  2YJ2 A;  1GEC E;  3PHW A;  1CTE A;  1XKG A;  4BOZ A;  2YJC A;  3IV2 A;  4OEL A;  4BS6 A;  5J94 A;  3DF0 A;  3PW3 A;  2HHN A;  1YK7 A;  3OIS A;  2OZ2 A;  2E00 A;  1QOL A;  2DCC A;  5EZQ A;  4BPV A;  2F7D A;  4P6G A;  4M0W A;  3KSE A;  1NB5 A;  1CVZ A;  2DC7 A;  9PAP A;  1PPO A;  5CVM A;  1JQP A;  3MP2 A;  4R3D A;  2AGA A;  2P0R A;  4YYU A;  2R6N A;  2G6D A;  3B79 A;  5JZE A;  3MHH A;  1KHP A;  3W30 A;  2CIO A;  3BCN A;  2DZZ A;  1VSN A;  1AU0 A;  1AYV A;  1EWM A;  1GLO A;  4MI7 A;  1Y08 A;  2F1G A;  5CVN B;  1AIM A;  1SNK A;  5JA7 A;  2YJB A;  2G8J A;  1PPN A;  4QRV A;  3BWK A;  3OVX A;  3H8C A;  1AYW A;  1ME3 A;  4QRX A;  3HHA A;  2ARY A;  2J7Q A;  3C9E A;  1U9X A;  3M99 A;  4RKX A;  1BGO A;  2HH5 A;  4P6E A;  6PAD A;  4RNA A;  3PDF A;  4YVA A;  2B1M A;  4PT5 A;  4YYQ A;  5A24 A;  2AUX A;  3S3R A;  3OVZ A;  2FYE A;  4BS5 A;  2AYN A;  3K8U A;  4REZ A;  4MM3 B;  1STF E;  2JQF R;  3KKU A;  2DCB A;  1IWD A;  5E6J A;  3PSE A;  4KLB A;  2JQG R;  2FO5 A;  3PT2 A;  4OVZ B;  2CB5 A;  2NQG A;  2JRI A;  2G8E A;  2DC9 A;  2NQI A;  4CDD B;  5CVO B;  2DJG B;  1MHW A;  2Y5B A;  3BPM A;  2IPP B;  3MJ5 A;  2NQD B;  3BB7 A;  4W4U A;  1ITO A;  1Y4H A;  3RVX A;  4AXM A;  1ME4 A;  2AIM A;  1UKF A;  4Q8H A;  4QH6 A;  3IEJ A;  4OVZ A;  3TNX A;  4PP1 A;  5F02 A;  1DF0 A;  2YJ8 A;  1AYU A;  3IMA A;  3F75 A;  2PRE A;  4I07 A;  3ZUA A;  4CZW A;  4FIP A;  2ACT A;  2IBI A;  3KW9 A;  1PIP A;  1U9Q X;  3PRP A;  4D8E A;  3I3T A;  3GCB A;  2VHF A;  3HWN A;  2PNS A;  4A5U A;  4OEM A;  1O0E A;  3BPF A;  3USV A;  3LXS A;  4X6J A;  1CQD A;  2G7Y A;  3H89 A;  2P86 A;  1QDQ A;  3N3G A;  3OF8 A;  1F29 A;  3QJ3 A;  3I06 A;  4BOQ A;  3P5X A;  1EF7 A;  1F2C A;  4YV8 A;  4FK5 A;  1CPJ A;  5EZS A;  4GUA A;  3E1Z B;  4I05 A;  3HHI A;  2PBH A;  1NL6 A;  4D8I A;  2DC8 A;  2BDL A;  4YYS A;  1AU2 A;  2UZJ A;  2DZY A;  3KWZ A;  4IP3 A;  4XUI A;  4ZTB A;  3IHP A;  5JH3 A;  1KXR A;  1PVJ A;  3IOQ A;  1NLJ A;  4PI3 A;  3V6E A;  2R9N A;  2BDZ A;  3IUT A;  4AXL A;  2WBF X;  4IUM A;  1KFU L;  3IFU A;  3PHX A;  4DMX A;  3B21 A;  4HXD B;  4RF1 A;  2XU3 A;  1KFX L;  3TMP A;  5KO3 A;  1U5I A;  3OF9 A;  4CDC B;  2E01 A;  2YJ9 A;  1MS6 A;  1KHQ A;  4PAD A;  3QT4 A;  4BOS A;  1YZB A;  4MZS A;  1Q6K A; 
#chains in the Genus database with same CATH homology
 3CH2 X;  2E03 A;  1M6D A;  1A6R A;  1YAL A;  1NPZ A;  2B1N A;  2H7J A;  2AUZ A;  3H7D A;  4MZO A;  1AU3 A;  1ATK A;  1S4V A;  3KFQ A;  2AS8 A;  5EGW A;  4ZUX U;  1MEG A;  4N4Z A;  3N4C A;  4QBB A;  1BQI A;  4W5C A;  3LFY A;  2FTD A;  1CB5 A;  4NV8 A;  5FPW A;  2ATO A;  2OP3 A;  1GCB A;  1K3B B;  1YK8 A;  4YYW A;  1TL9 A;  3O0U A;  1DEU A;  2XU4 A;  1ZIV A;  2P7U A;  2HD5 A;  7PCK A;  1MDW A;  1AU4 A;  1MEM A;  3MHS A;  2OUL A;  3BC3 A;  2R9O A;  2BSZ A;  5CHT A;  3P5W A;  4RY2 A;  2R9F A;  2PAD A;  2FQ9 A;  1ZCM A;  3K24 A;  1ICF A;  2C0Y A;  2FT2 A;  4X6I A;  3WXF A;  1QMY A;  3MTN A;  1POP A;  1W5R A;  2O6X A;  2R9M A;  2R9C A;  2XU1 A;  1F2B A;  1MIR A;  1PPP A;  4B55 A;  2FRQ A;  1BP4 A;  1FH0 A;  3O1G A;  1PXV A;  3V6C A;  4G54 A;  3N3K A;  1HUC B;  1BY8 A;  4DMY A;  3BOW A;  1PE6 A;  3D6S A;  3S3Q A;  4QRG A;  1TLO A;  3P5V A;  5K16 A;  2XU5 A;  2GHU A;  3D9W A;  1VJV A;  3U8E A;  1EWL A;  3P5U A;  4YYV A;  4I04 A;  1U9W A;  1F2A A;  2GFO A;  2DCD A;  2AU1 A;  2FUD A;  4W5B A;  1AEC A;  3CBJ A;  1PCI A;  2AYO A;  3AI8 A;  1YT7 A;  4MSX A;  1EWP A;  4WA6 A;  1CV8 A;  3KWB X;  3RVW A;  3H6S A;  1PPD A;  1E2T A;  3MOR A;  1QXP A;  4X6H A;  3QSD A;  2DCA A;  1X9Y A;  2FRA A;  4XR7 A;  2DC6 A;  1SP4 B;  1THE A;  4CDE B;  4BSQ A;  1U9V A;  3H8B A;  1PBH A;  3F5V A;  3RVV A;  5EF4 A;  4NV7 A;  2Y6E A;  3PBH A;  4N79 A;  1GMY A;  1YVB A;  2HXZ A;  3K9M A;  5PAD A;  2NQA A;  1NB3 A;  2E02 A;  4Q8G A;  3CBK A;  1CS8 A;  5CHV A;  3WXE A;  3CH3 X;  2VHS A;  4K7C A;  4FJC A;  3NHE A;  2DJF B;  4PP2 E;  4CDF B;  2AVW A;  3HD3 A;  3ERV A;  1TU6 A;  4N8W A;  4BQV A;  1NQC A;  8PCH A;  1EWO A;  3WXG A;  3KX1 A;  4HWY A;  3PNR A;  4YYR A;  1PAD A;  1CJL A;  1CSB B;  2YJ2 A;  1GEC E;  1CTE A;  1XKG A;  2YJC A;  3IV2 A;  4OEL A;  4BS6 A;  5J94 A;  3DF0 A;  3PW3 A;  2HHN A;  1YK7 A;  3OIS A;  2OZ2 A;  2E00 A;  1QOL A;  2DCC A;  4BPV A;  2F7D A;  4P6G A;  3KSE A;  1NB5 A;  1CVZ A;  2DC7 A;  9PAP A;  1PPO A;  5CVM A;  1JQP A;  1W4T A;  2P0R A;  4YYU A;  2R6N A;  2G6D A;  3B79 A;  3MHH A;  1KHP A;  2CIO A;  3BCN A;  2DZZ A;  1VSN A;  1AU0 A;  1AYV A;  1EWM A;  1GLO A;  1Y08 A;  2F1G A;  5CVN B;  1AIM A;  1SNK A;  5JA7 A;  2VFB A;  2YJB A;  2G8J A;  1PPN A;  4QRV A;  3BWK A;  3OVX A;  2VFC A;  3H8C A;  1AYW A;  1ME3 A;  4QRX A;  3HHA A;  4BGF A;  2ARY A;  3C9E A;  1U9X A;  3M99 A;  1BGO A;  2HH5 A;  4P6E A;  6PAD A;  3PDF A;  4YVA A;  2B1M A;  1GX3 A;  4YYQ A;  5A24 A;  2AUX A;  3S3R A;  3OVZ A;  2FYE A;  4BS5 A;  2AYN A;  3K8U A;  1STF E;  2JQF R;  3KKU A;  2DCB A;  1IWD A;  4KLB A;  2JQG R;  2FO5 A;  2CB5 A;  2NQG A;  2G8E A;  2DC9 A;  2NQI A;  4CDD B;  5CVO B;  2DJG B;  1MHW A;  2Y5B A;  3BPM A;  2IPP B;  2NQD B;  4W4U A;  1ITO A;  1Y4H A;  3RVX A;  4AXM A;  1ME4 A;  2AIM A;  4Q8H A;  4QH6 A;  3IEJ A;  1W6F A;  4PP1 A;  3TNX A;  5F02 A;  1DF0 A;  2YJ8 A;  3LTW A;  1AYU A;  3IMA A;  3F75 A;  2PRE A;  4I07 A;  3ZUA A;  4CZW A;  4FIP A;  2ACT A;  2IBI A;  3KW9 A;  1PIP A;  1U9Q X;  4C5P A;  3I3T A;  3GCB A;  2VHF A;  3HWN A;  2PNS A;  4OEM A;  1O0E A;  3BPF A;  3USV A;  3LXS A;  4X6J A;  1CQD A;  2G7Y A;  3H89 A;  2P86 A;  1QDQ A;  3N3G A;  3OF8 A;  1F29 A;  3QJ3 A;  3I06 A;  3P5X A;  1EF7 A;  1F2C A;  4YV8 A;  4FK5 A;  1CPJ A;  3E1Z B;  4I05 A;  3HHI A;  2PBH A;  1NL6 A;  2DC8 A;  2BDL A;  4YYS A;  1AU2 A;  2DZY A;  3KWZ A;  4XUI A;  3IHP A;  5JH3 A;  4GUZ A;  1KXR A;  3IOQ A;  1NLJ A;  4PI3 A;  3V6E A;  2R9N A;  2BDZ A;  3IUT A;  4AXL A;  2WBF X;  1KFU L;  4DMX A;  2XU3 A;  1KFX L;  1U5I A;  3OF9 A;  4CDC B;  2E01 A;  2YJ9 A;  1MS6 A;  1KHQ A;  4PAD A;  3QT4 A;  4MZS A;  1Q6K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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