1U9XA

Crystal structure of the cysteine protease human cathepsin k in complex with the covalent inhibitor nvp-abj688
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
216
structure length
216
Chain Sequence
RAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Novel purine nitrile derived inhibitors of the cysteine protease cathepsin K
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Cathepsin K
total genus 63
structure length 216
sequence length 216
ec nomenclature ec 3.4.22.38: Cathepsin K.
pdb deposition date 2004-08-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1u9xA00
4FIPA 4OELA 3C9EA 3O0UA 2R6NA 1VSNA 4BS6A 1SNKA 1X9YA 1DEUA 2HD5A 3H7DA 3MTNA 1PIPA 4BSQA 1BGOA 3I3TA 4CDEB 3H8CA 5EF4A 3BCNA 1AU4A 3P5UA 1MIRA 1AU0A 2E00A 2BDZA 5FPWA 2G7YA 4YYQA 2B1MA 1SP4B 6PADA 1AU2A 3BC3A 4BS5A 4HWYA 3P5XA 1Q6KA 1BY8A 4YYUA 3H89A 4N8WA 1F2CA 1Y4HA 1FH0A 1MDWA 2G8EA 2CIOA 1U9XA 3S3QA 1NL6A 3WXFA 4Q8GA 5K16A 1KHQA 1CTEA 2AVWA 1F2AA 3ZUAA 3CBJA 1YT7A 2DJFB 1TL9A 3PDFA 3GCBA 2FQ9A 3USVA 4AXLA 3N3GA 4BPVA 3NHEA 3BPMA 1QDQA 1PXVA 3B79A 4XR7A 3WXGA 3OISA 9PAPA 1PPDA 2AUXA 2F1GA 1ICFA 5CVMA 1CJLA 3O1GA 1TLOA 2FTDA 2DCBA 1EWMA 1CSBB 4QRVA 4I04A 1F29A 3TNXA 1AYUA 4YVAA 1PADA 4MSXA 4Q8HA 4PP1A 3BOWA 2DC6A 3V6CA 4KLBA 1YK8A 2OP3A 1EWOA 1AIMA 3IUTA 3S3RA 2NQDB 1NQCA 2AYNA 3PNRA 2JQFR 3F75A 1PCIA 2PNSA 4YV8A 4PI3A 2B1NA 2HHNA 3QJ3A 3HD3A 2E03A 1CB5A 2OULA 2HH5A 1PPPA 4YYSA 4XUIA 4W4UA 3OF8A 1NLJA 1ME4A 1JQPA 2VHFA 1GMYA 1M6DA 5CHTA 4QBBA 1GCBA 2R9FA 7PCKA 3KKUA 3BWKA 5A24A 4N4ZA 2DC7A 4CZWA 2PADA 3H6SA 2NQAA 3K9MA 4FJCA 2DC8A 1IWDA 2P0RA 2DZYA 1THEA 1QOLA 4BQVA 4ZUXU 3CH2X 3OF9A 2XU3A 1CS8A 2CB5A 2AUZA 2DCDA 8PCHA 1U9WA 2F7DA 2NQGA 3RVWA 1ATKA 3KWZA 3KX1A 2YJ2A 5JH3A 4RY2A 1MS6A 4K7CA 2E01A 2O6XA 2IBIA 2R9MA 2FRQA 1KFUL 2XU4A 1DF0A 3I06A 1CV8A 3IOQA 2YJBA 1A6RA 2GFOA 4I07A 3OVXA 1F2BA 1CPJA 3K24A 1EWPA 4AXMA 3IHPA 2G6DA 1U5IA 1PBHA 3E1ZB 4CDFB 2ACTA 1NB5A 5JA7A 4MZOA 3HHIA 3N4CA 3AI8A 4CDDB 3IMAA 4W5CA 4DMXA 3HWNA 1NB3A 1PPNA 2FT2A 4I05A 4P6EA 2PREA 2AU1A 4YYWA 1K3BB 3D6SA 1QMYA 1GLOA 1HUCB 3ERVA 1KHPA 2YJ8A 3CH3X 1U9QX 5F02A 4QRGA 2NQIA 1BQIA 2AIMA 1QXPA 1YALA 3MORA 2HXZA 3V6EA 2DCAA 1AECA 4PP2E 2FYEA 1NPZA 2R9NA 2PBHA 2XU1A 2ARYA 4WA6A 1ZCMA 4P6GA 2DJGB 2IPPB 3HHAA 1GECE 1PPOA 2Y5BA 2AS8A 1EWLA 3PW3A 2YJ9A 1XKGA 1MEMA 3IV2A 2VHSA 1POPA 1VJVA 1AYVA 3IEJA 1EF7A 1MEGA 5J94A 5CHVA 2AYOA 1U9VA 1AU3A 2R9CA 4X6HA 1S4VA 2BDLA 3QSDA 2DZZA 2P86A 4MZSA 1TU6A 4DMYA 3P5VA 4W5BA 2ATOA 1ITOA 2XU5A 5PADA 4G54A 4QH6A 1KXRA 2R9OA 2WBFX 3CBKA 3LFYA 3BPFA 3MHSA 3KW9A 1O0EA 3WXEA 3RVVA 1CQDA 4QRXA 5EGWA 4CDCB 2FUDA 2C0YA 2YJCA 4YYRA 2G8JA 2DC9A 1YK7A 2DCCA 2GHUA 1PE6A 2Y6EA 3F5VA 4OEMA 5CVNB 2JQGR 1YVBA 3OVZA 4YYVA 3K8UA 3MHHA 2H7JA 1MHWA 2FO5A 3KWBX 1Y08A 3M99A 2E02A 4PADA 4X6JA 3PBHA 2OZ2A 3QT4A 3H8BA 3KSEA 5CVOB 1ZIVA 3KFQA 1KFXL 4X6IA 1AYWA 2FRAA 3P5WA 4FK5A 1ME3A 3DF0A 1BP4A 1CVZA 3LXSA 4N79A 3RVXA 3U8EA 1STFE 3N3KA 2P7UA
chains in the Genus database with same CATH superfamily
4FIPA 4OELA 3C9EA 3O0UA 2R6NA 1VSNA 4BS6A 1SNKA 1X9YA 1DEUA 2HD5A 3H7DA 3MTNA 1PIPA 4BSQA 5E6JA 1BGOA 3I3TA 2UZJA 4CDEB 3H8CA 3MJ5A 5EF4A 3BCNA 1AU4A 3P5UA 1MIRA 1AU0A 2E00A 2BDZA 5FPWA 2G7YA 4YYQA 4WURA 2B1MA 3PRPA 1SP4B 3PT2A 6PADA 1AU2A 3BC3A 4M0WA 4BS5A 4HWYA 3P5XA 1Q6KA 1BY8A 4YYUA 3H89A 4N8WA 5KO3A 1F2CA 1Y4HA 1FH0A 1MDWA 2G8EA 2CIOA 3BBAA 4OW0A 4PT5A 4RF0A 1U9XA 3S3QA 2DOSA 1NL6A 3WXFA 4Q8GA 4XZXA 5K16A 1KHQA 1CTEA 2AVWA 1F2AA 3ZUAA 3CBJA 4ZTBA 4R3DA 1YT7A 2DJFB 1TL9A 3PDFA 3GCBA 2FQ9A 3USVA 4AXLA 3N3GA 4BPVA 3NHEA 3BPMA 1QDQA 1PXVA 3B79A 4XR7A 5EZQA 2JRIA 3WXGA 3OISA 9PAPA 4A5UA 1PPDA 2AUXA 2F1GA 1ICFA 5CVMA 3W31A 1CJLA 3O1GA 1TLOA 2FTDA 2DCBA 1EWMA 3E9SA 1CSBB 4QRVA 4I04A 3C0RA 1F29A 3TNXA 1AYUA 4YVAA 1PADA 4RF1A 4MSXA 4Q8HA 4PP1A 3BOWA 2DC6A 3V6CA 4KLBA 1YK8A 2OP3A 1EWOA 1AIMA 3IUTA 3S3RA 2NQDB 1NQCA 2AYNA 3PNRA 2JQFR 2Z84A 4D8EA 3F75A 1PCIA 2PNSA 4YV8A 4PI3A 2B1NA 2HHNA 3QJ3A 3HD3A 2E03A 1CB5A 2OULA 2HH5A 1PPPA 4YYSA 4XUIA 4W4UA 3OF8A 1NLJA 1ME4A 1JQPA 4BOQA 3MTVA 2VHFA 3OQCA 1GMYA 3O65A 1M6DA 5CHTA 2J7QA 4QBBA 1GCBA 2R9FA 7PCKA 3KKUA 3BWKA 5A24A 4N4ZA 2DC7A 4D8IA 4CZWA 2PADA 3H6SA 2NQAA 3K9MA 4FJCA 2DC8A 3MP2A 1IWDA 2P0RA 4GUAA 2DZYA 1THEA 1QOLA 4BQVA 3PHUA 4ZUXU 4OVZA 3CH2X 3OF9A 2XU3A 1CS8A 2CB5A 2AUZA 2DCDA 8PCHA 2BTWA 1U9WA 2F7DA 2NQGA 3RVWA 1ATKA 3KWZA 3KX1A 3TMPA 2YJ2A 5JH3A 3W30A 3TRKA 4RY2A 1MS6A 4K7CA 2E01A 2O6XA 2IBIA 2R9MA 2FRQA 1KFUL 2XU4A 1DF0A 3I06A 1CV8A 3IOQA 2YJBA 1A6RA 2GFOA 2BU3A 4I07A 3OVXA 1F2BA 1CPJA 4MM3B 3K24A 1EWPA 4AXMA 4IP3A 1UKFA 3IHPA 4P16A 3PHXA 2G6DA 1U5IA 1PBHA 4REZA 3E1ZB 4CDFB 2ACTA 4BOSA 1NB5A 5JA7A 4MZOA 3HHIA 5JZEA 3N4CA 3AI8A 4RKXA 4CDDB 3IMAA 4W5CA 4DMXA 3HWNA 1NB3A 1PPNA 2FT2A 4I05A 4P6EA 2PREA 2AU1A 4YYWA 1K3BB 3D6SA 1QMYA 1GLOA 1HUCB 3ERVA 1KHPA 2YJ8A 3CH3X 1U9QX 5F02A 4QRGA 2NQIA 1BQIA 2AIMA 1QXPA 1YALA 3MORA 2HXZA 3V6EA 4D8BA 3BB7A 2DCAA 1AECA 3B21A 4PP2E 5EZSA 2FYEA 1NPZA 2R9NA 1PVJA 2PBHA 2XU1A 2ARYA 4WA6A 3PRMA 1ZCMA 4P6GA 2DJGB 2IPPB 3HHAA 1GECE 4OVZB 1PPOA 2Y5BA 2AS8A 1EWLA 3PW3A 2BTWB 2YJ9A 1XKGA 1MEMA 4HXDB 3PSEA 3IV2A 2AGAA 2VHSA 1POPA 1VJVA 4BOPA 1AYVA 3IEJA 1EF7A 1MEGA 4IUMA 5J94A 5CHVA 2AYOA 1U9VA 1YZBA 1AU3A 2R9CA 4X6HA 1S4VA 2BDLA 3QSDA 2DZZA 2P86A 4MZSA 1TU6A 4DMYA 3ZNHA 3P5VA 4W5BA 2ATOA 1ITOA 2XU5A 5PADA 4G54A 4QH6A 1DKIA 1KXRA 3RNVA 2R9OA 4BOZA 2WBFX 3CBKA 3LFYA 3BPFA 3MHSA 3KW9A 1O0EA 3WXEA 3RVVA 4MI7A 1CQDA 4QRXA 5EGWA 4CDCB 2FUDA 2HWKA 2C0YA 2YJCA 3BY4A 3PHWA 4YYRA 2G8JA 2DC9A 1YK7A 2DCCA 2GHUA 1PE6A 2Y6EA 3F5VA 4OEMA 5CVNB 4BOUA 2JQGR 1YVBA 3OVZA 4RNAA 4YYVA 3K8UA 3MHHA 2H7JA 1MHWA 2FO5A 3KWBX 1Y08A 3M99A 2E02A 4PADA 4X6JA 3PBHA 2J7QC 2OZ2A 3IFUA 3QT4A 3H8BA 3KSEA 5CVOB 1ZIVA 2JTCA 2FE8A 3KFQA 1KFXL 4X6IA 1AYWA 2FRAA 3P5WA 4FK5A 1ME3A 3DF0A 1BP4A 1CVZA 3LXSA 4N79A 3RVXA 3U8EA 1STFE 3N3KA 2P7UA
chains in the Genus database with same CATH topology
4FIPA 4OELA 3C9EA 3O0UA 2R6NA 1VSNA 4BS6A 1SNKA 1X9YA 1DEUA 2HD5A 3H7DA 3MTNA 1PIPA 4BSQA 1BGOA 3I3TA 4CDEB 3H8CA 5EF4A 3BCNA 1AU4A 3P5UA 1MIRA 1AU0A 2E00A 2BDZA 5FPWA 2G7YA 4YYQA 2B1MA 1SP4B 6PADA 1AU2A 3BC3A 4BS5A 4HWYA 3P5XA 1Q6KA 1BY8A 4YYUA 3H89A 4N8WA 1F2CA 1Y4HA 1FH0A 1MDWA 2G8EA 2CIOA 1U9XA 3S3QA 1NL6A 3WXFA 4Q8GA 5K16A 1KHQA 1CTEA 2AVWA 1F2AA 3ZUAA 3CBJA 1YT7A 2DJFB 1TL9A 3PDFA 3GCBA 2FQ9A 3USVA 4AXLA 3N3GA 4BPVA 3D9WA 4NV8A 3NHEA 3BPMA 1QDQA 1PXVA 3B79A 4XR7A 3WXGA 3OISA 9PAPA 1PPDA 2AUXA 2F1GA 1ICFA 5CVMA 1CJLA 3O1GA 1TLOA 2VFCA 2FTDA 2DCBA 1EWMA 1CSBB 4QRVA 4I04A 1F29A 3TNXA 1AYUA 4YVAA 1PADA 4MSXA 4Q8HA 4PP1A 3BOWA 2DC6A 3V6CA 4KLBA 1YK8A 2OP3A 1EWOA 1AIMA 3IUTA 3S3RA 2NQDB 1NQCA 2AYNA 3PNRA 2JQFR 3F75A 1PCIA 2PNSA 4YV8A 4PI3A 2B1NA 2HHNA 3QJ3A 3HD3A 2E03A 4B55A 1CB5A 2OULA 4BGFA 2HH5A 1PPPA 1W4TA 4YYSA 4XUIA 1W6FA 4W4UA 3OF8A 1NLJA 1ME4A 1JQPA 2VHFA 1GMYA 1M6DA 5CHTA 4QBBA 1GCBA 2R9FA 7PCKA 3KKUA 3BWKA 5A24A 4N4ZA 1E2TA 2DC7A 4CZWA 2PADA 3H6SA 2NQAA 3K9MA 4FJCA 2DC8A 1IWDA 2P0RA 2DZYA 1THEA 1QOLA 4BQVA 4ZUXU 3CH2X 3OF9A 2XU3A 1CS8A 2CB5A 2AUZA 2DCDA 8PCHA 1U9WA 2F7DA 2NQGA 3RVWA 1ATKA 3KWZA 3KX1A 2YJ2A 5JH3A 3LTWA 4RY2A 1MS6A 4K7CA 2E01A 2O6XA 2IBIA 2R9MA 2FRQA 1KFUL 2XU4A 1DF0A 3I06A 1CV8A 3IOQA 2YJBA 1A6RA 2GFOA 4I07A 3OVXA 1F2BA 1CPJA 3K24A 1EWPA 4AXMA 2BSZA 3IHPA 2G6DA 1U5IA 1PBHA 3E1ZB 4CDFB 2ACTA 1NB5A 5JA7A 4MZOA 3HHIA 3N4CA 3AI8A 4CDDB 3IMAA 4W5CA 4DMXA 3HWNA 1NB3A 1PPNA 2FT2A 4I05A 4P6EA 2PREA 2AU1A 4YYWA 1K3BB 3D6SA 1QMYA 4C5PA 1GLOA 1HUCB 3ERVA 2VFBA 1KHPA 2YJ8A 3CH3X 1U9QX 5F02A 4QRGA 2NQIA 1BQIA 2AIMA 1QXPA 1YALA 3MORA 2HXZA 3V6EA 2DCAA 1AECA 4PP2E 2FYEA 1NPZA 2R9NA 2PBHA 2XU1A 2ARYA 4WA6A 4GUZA 1ZCMA 4P6GA 2DJGB 4NV7A 2IPPB 3HHAA 1GECE 1PPOA 2Y5BA 2AS8A 1EWLA 3PW3A 2YJ9A 1XKGA 1MEMA 3IV2A 2VHSA 1POPA 1VJVA 1AYVA 3IEJA 1EF7A 1MEGA 1GX3A 5J94A 5CHVA 2AYOA 1U9VA 1AU3A 2R9CA 4X6HA 1S4VA 2BDLA 3QSDA 2DZZA 2P86A 4MZSA 1TU6A 4DMYA 3P5VA 4W5BA 2ATOA 1ITOA 2XU5A 5PADA 4G54A 4QH6A 1KXRA 2R9OA 2WBFX 3CBKA 3LFYA 3BPFA 3MHSA 3KW9A 1O0EA 3WXEA 3RVVA 1CQDA 4QRXA 5EGWA 4CDCB 2FUDA 2C0YA 2YJCA 4YYRA 2G8JA 2DC9A 1YK7A 2DCCA 2GHUA 1PE6A 2Y6EA 3F5VA 4OEMA 5CVNB 2JQGR 1YVBA 3OVZA 4YYVA 3K8UA 3MHHA 2H7JA 1MHWA 2FO5A 3KWBX 1Y08A 3M99A 2E02A 4PADA 4X6JA 3PBHA 2OZ2A 1W5RA 3QT4A 3H8BA 3KSEA 5CVOB 1ZIVA 3KFQA 1KFXL 4X6IA 1AYWA 2FRAA 3P5WA 4FK5A 1ME3A 3DF0A 1BP4A 1CVZA 3LXSA 4N79A 3RVXA 3U8EA 1STFE 3N3KA 2P7UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FIP A;  4OEL A;  3C9E A;  3O0U A;  2R6N A;  1VSN A;  4BS6 A;  1SNK A;  1X9Y A;  1DEU A;  2HD5 A;  3H7D A;  3MTN A;  1PIP A;  4BSQ A;  1BGO A;  3I3T A;  4CDE B;  3H8C A;  5EF4 A;  3BCN A;  1AU4 A;  3P5U A;  1MIR A;  1AU0 A;  2E00 A;  2BDZ A;  5FPW A;  2G7Y A;  4YYQ A;  2B1M A;  1SP4 B;  6PAD A;  1AU2 A;  3BC3 A;  4BS5 A;  4HWY A;  3P5X A;  1Q6K A;  1BY8 A;  4YYU A;  3H89 A;  4N8W A;  1F2C A;  1Y4H A;  1FH0 A;  1MDW A;  2G8E A;  2CIO A;  1U9X A;  3S3Q A;  1NL6 A;  3WXF A;  4Q8G A;  5K16 A;  1KHQ A;  1CTE A;  2AVW A;  1F2A A;  3ZUA A;  3CBJ A;  1YT7 A;  2DJF B;  1TL9 A;  3PDF A;  3GCB A;  2FQ9 A;  3USV A;  4AXL A;  3N3G A;  4BPV A;  3NHE A;  3BPM A;  1QDQ A;  1PXV A;  3B79 A;  4XR7 A;  3WXG A;  3OIS A;  9PAP A;  1PPD A;  2AUX A;  2F1G A;  1ICF A;  5CVM A;  1CJL A;  3O1G A;  1TLO A;  2FTD A;  2DCB A;  1EWM A;  1CSB B;  4QRV A;  4I04 A;  1F29 A;  3TNX A;  1AYU A;  4YVA A;  1PAD A;  4MSX A;  4Q8H A;  4PP1 A;  3BOW A;  2DC6 A;  3V6C A;  4KLB A;  1YK8 A;  2OP3 A;  1EWO A;  1AIM A;  3IUT A;  3S3R A;  2NQD B;  1NQC A;  2AYN A;  3PNR A;  2JQF R;  3F75 A;  1PCI A;  2PNS A;  4YV8 A;  4PI3 A;  2B1N A;  2HHN A;  3QJ3 A;  3HD3 A;  2E03 A;  1CB5 A;  2OUL A;  2HH5 A;  1PPP A;  4YYS A;  4XUI A;  4W4U A;  3OF8 A;  1NLJ A;  1ME4 A;  1JQP A;  2VHF A;  1GMY A;  1M6D A;  5CHT A;  4QBB A;  1GCB A;  2R9F A;  7PCK A;  3KKU A;  3BWK A;  5A24 A;  4N4Z A;  2DC7 A;  4CZW A;  2PAD A;  3H6S A;  2NQA A;  3K9M A;  4FJC A;  2DC8 A;  1IWD A;  2P0R A;  2DZY A;  1THE A;  1QOL A;  4BQV A;  4ZUX U;  3CH2 X;  3OF9 A;  2XU3 A;  1CS8 A;  2CB5 A;  2AUZ A;  2DCD A;  8PCH A;  1U9W A;  2F7D A;  2NQG A;  3RVW A;  1ATK A;  3KWZ A;  3KX1 A;  2YJ2 A;  5JH3 A;  4RY2 A;  1MS6 A;  4K7C A;  2E01 A;  2O6X A;  2IBI A;  2R9M A;  2FRQ A;  1KFU L;  2XU4 A;  1DF0 A;  3I06 A;  1CV8 A;  3IOQ A;  2YJB A;  1A6R A;  2GFO A;  4I07 A;  3OVX A;  1F2B A;  1CPJ A;  3K24 A;  1EWP A;  4AXM A;  3IHP A;  2G6D A;  1U5I A;  1PBH A;  3E1Z B;  4CDF B;  2ACT A;  1NB5 A;  5JA7 A;  4MZO A;  3HHI A;  3N4C A;  3AI8 A;  4CDD B;  3IMA A;  4W5C A;  4DMX A;  3HWN A;  1NB3 A;  1PPN A;  2FT2 A;  4I05 A;  4P6E A;  2PRE A;  2AU1 A;  4YYW A;  1K3B B;  3D6S A;  1QMY A;  1GLO A;  1HUC B;  3ERV A;  1KHP A;  2YJ8 A;  3CH3 X;  1U9Q X;  5F02 A;  4QRG A;  2NQI A;  1BQI A;  2AIM A;  1QXP A;  1YAL A;  3MOR A;  2HXZ A;  3V6E A;  2DCA A;  1AEC A;  4PP2 E;  2FYE A;  1NPZ A;  2R9N A;  2PBH A;  2XU1 A;  2ARY A;  4WA6 A;  1ZCM A;  4P6G A;  2DJG B;  2IPP B;  3HHA A;  1GEC E;  1PPO A;  2Y5B A;  2AS8 A;  1EWL A;  3PW3 A;  2YJ9 A;  1XKG A;  1MEM A;  3IV2 A;  2VHS A;  1POP A;  1VJV A;  1AYV A;  3IEJ A;  1EF7 A;  1MEG A;  5J94 A;  5CHV A;  2AYO A;  1U9V A;  1AU3 A;  2R9C A;  4X6H A;  1S4V A;  2BDL A;  3QSD A;  2DZZ A;  2P86 A;  4MZS A;  1TU6 A;  4DMY A;  3P5V A;  4W5B A;  2ATO A;  1ITO A;  2XU5 A;  5PAD A;  4G54 A;  4QH6 A;  1KXR A;  2R9O A;  2WBF X;  3CBK A;  3LFY A;  3BPF A;  3MHS A;  3KW9 A;  1O0E A;  3WXE A;  3RVV A;  1CQD A;  4QRX A;  5EGW A;  4CDC B;  2FUD A;  2C0Y A;  2YJC A;  4YYR A;  2G8J A;  2DC9 A;  1YK7 A;  2DCC A;  2GHU A;  1PE6 A;  2Y6E A;  3F5V A;  4OEM A;  5CVN B;  2JQG R;  1YVB A;  3OVZ A;  4YYV A;  3K8U A;  3MHH A;  2H7J A;  1MHW A;  2FO5 A;  3KWB X;  1Y08 A;  3M99 A;  2E02 A;  4PAD A;  4X6J A;  3PBH A;  2OZ2 A;  3QT4 A;  3H8B A;  3KSE A;  5CVO B;  1ZIV A;  3KFQ A;  1KFX L;  4X6I A;  1AYW A;  2FRA A;  3P5W A;  4FK5 A;  1ME3 A;  3DF0 A;  1BP4 A;  1CVZ A;  3LXS A;  4N79 A;  3RVX A;  3U8E A;  1STF E;  3N3K A;  2P7U A; 
#chains in the Genus database with same CATH topology
 4FIP A;  4OEL A;  3C9E A;  3O0U A;  2R6N A;  1VSN A;  4BS6 A;  1SNK A;  1X9Y A;  1DEU A;  2HD5 A;  3H7D A;  3MTN A;  1PIP A;  4BSQ A;  5E6J A;  1BGO A;  3I3T A;  2UZJ A;  4CDE B;  3H8C A;  3MJ5 A;  5EF4 A;  3BCN A;  1AU4 A;  3P5U A;  1MIR A;  1AU0 A;  2E00 A;  2BDZ A;  5FPW A;  2G7Y A;  4YYQ A;  4WUR A;  2B1M A;  3PRP A;  1SP4 B;  3PT2 A;  6PAD A;  1AU2 A;  3BC3 A;  4M0W A;  4BS5 A;  4HWY A;  3P5X A;  1Q6K A;  1BY8 A;  4YYU A;  3H89 A;  4N8W A;  5KO3 A;  1F2C A;  1Y4H A;  1FH0 A;  1MDW A;  2G8E A;  2CIO A;  3BBA A;  4OW0 A;  4PT5 A;  4RF0 A;  1U9X A;  3S3Q A;  2DOS A;  1NL6 A;  3WXF A;  4Q8G A;  4XZX A;  5K16 A;  1KHQ A;  1CTE A;  2AVW A;  1F2A A;  3ZUA A;  3CBJ A;  4ZTB A;  4R3D A;  1YT7 A;  2DJF B;  1TL9 A;  3PDF A;  3GCB A;  2FQ9 A;  3USV A;  4AXL A;  3N3G A;  4BPV A;  3NHE A;  3BPM A;  1QDQ A;  1PXV A;  3B79 A;  4XR7 A;  5EZQ A;  2JRI A;  3WXG A;  3OIS A;  9PAP A;  4A5U A;  1PPD A;  2AUX A;  2F1G A;  1ICF A;  5CVM A;  3W31 A;  1CJL A;  3O1G A;  1TLO A;  2FTD A;  2DCB A;  1EWM A;  3E9S A;  1CSB B;  4QRV A;  4I04 A;  3C0R A;  1F29 A;  3TNX A;  1AYU A;  4YVA A;  1PAD A;  4RF1 A;  4MSX A;  4Q8H A;  4PP1 A;  3BOW A;  2DC6 A;  3V6C A;  4KLB A;  1YK8 A;  2OP3 A;  1EWO A;  1AIM A;  3IUT A;  3S3R A;  2NQD B;  1NQC A;  2AYN A;  3PNR A;  2JQF R;  2Z84 A;  4D8E A;  3F75 A;  1PCI A;  2PNS A;  4YV8 A;  4PI3 A;  2B1N A;  2HHN A;  3QJ3 A;  3HD3 A;  2E03 A;  1CB5 A;  2OUL A;  2HH5 A;  1PPP A;  4YYS A;  4XUI A;  4W4U A;  3OF8 A;  1NLJ A;  1ME4 A;  1JQP A;  4BOQ A;  3MTV A;  2VHF A;  3OQC A;  1GMY A;  3O65 A;  1M6D A;  5CHT A;  2J7Q A;  4QBB A;  1GCB A;  2R9F A;  7PCK A;  3KKU A;  3BWK A;  5A24 A;  4N4Z A;  2DC7 A;  4D8I A;  4CZW A;  2PAD A;  3H6S A;  2NQA A;  3K9M A;  4FJC A;  2DC8 A;  3MP2 A;  1IWD A;  2P0R A;  4GUA A;  2DZY A;  1THE A;  1QOL A;  4BQV A;  3PHU A;  4ZUX U;  4OVZ A;  3CH2 X;  3OF9 A;  2XU3 A;  1CS8 A;  2CB5 A;  2AUZ A;  2DCD A;  8PCH A;  2BTW A;  1U9W A;  2F7D A;  2NQG A;  3RVW A;  1ATK A;  3KWZ A;  3KX1 A;  3TMP A;  2YJ2 A;  5JH3 A;  3W30 A;  3TRK A;  4RY2 A;  1MS6 A;  4K7C A;  2E01 A;  2O6X A;  2IBI A;  2R9M A;  2FRQ A;  1KFU L;  2XU4 A;  1DF0 A;  3I06 A;  1CV8 A;  3IOQ A;  2YJB A;  1A6R A;  2GFO A;  2BU3 A;  4I07 A;  3OVX A;  1F2B A;  1CPJ A;  4MM3 B;  3K24 A;  1EWP A;  4AXM A;  4IP3 A;  1UKF A;  3IHP A;  4P16 A;  3PHX A;  2G6D A;  1U5I A;  1PBH A;  4REZ A;  3E1Z B;  4CDF B;  2ACT A;  4BOS A;  1NB5 A;  5JA7 A;  4MZO A;  3HHI A;  5JZE A;  3N4C A;  3AI8 A;  4RKX A;  4CDD B;  3IMA A;  4W5C A;  4DMX A;  3HWN A;  1NB3 A;  1PPN A;  2FT2 A;  4I05 A;  4P6E A;  2PRE A;  2AU1 A;  4YYW A;  1K3B B;  3D6S A;  1QMY A;  1GLO A;  1HUC B;  3ERV A;  1KHP A;  2YJ8 A;  3CH3 X;  1U9Q X;  5F02 A;  4QRG A;  2NQI A;  1BQI A;  2AIM A;  1QXP A;  1YAL A;  3MOR A;  2HXZ A;  3V6E A;  4D8B A;  3BB7 A;  2DCA A;  1AEC A;  3B21 A;  4PP2 E;  5EZS A;  2FYE A;  1NPZ A;  2R9N A;  1PVJ A;  2PBH A;  2XU1 A;  2ARY A;  4WA6 A;  3PRM A;  1ZCM A;  4P6G A;  2DJG B;  2IPP B;  3HHA A;  1GEC E;  4OVZ B;  1PPO A;  2Y5B A;  2AS8 A;  1EWL A;  3PW3 A;  2BTW B;  2YJ9 A;  1XKG A;  1MEM A;  4HXD B;  3PSE A;  3IV2 A;  2AGA A;  2VHS A;  1POP A;  1VJV A;  4BOP A;  1AYV A;  3IEJ A;  1EF7 A;  1MEG A;  4IUM A;  5J94 A;  5CHV A;  2AYO A;  1U9V A;  1YZB A;  1AU3 A;  2R9C A;  4X6H A;  1S4V A;  2BDL A;  3QSD A;  2DZZ A;  2P86 A;  4MZS A;  1TU6 A;  4DMY A;  3ZNH A;  3P5V A;  4W5B A;  2ATO A;  1ITO A;  2XU5 A;  5PAD A;  4G54 A;  4QH6 A;  1DKI A;  1KXR A;  3RNV A;  2R9O A;  4BOZ A;  2WBF X;  3CBK A;  3LFY A;  3BPF A;  3MHS A;  3KW9 A;  1O0E A;  3WXE A;  3RVV A;  4MI7 A;  1CQD A;  4QRX A;  5EGW A;  4CDC B;  2FUD A;  2HWK A;  2C0Y A;  2YJC A;  3BY4 A;  3PHW A;  4YYR A;  2G8J A;  2DC9 A;  1YK7 A;  2DCC A;  2GHU A;  1PE6 A;  2Y6E A;  3F5V A;  4OEM A;  5CVN B;  4BOU A;  2JQG R;  1YVB A;  3OVZ A;  4RNA A;  4YYV A;  3K8U A;  3MHH A;  2H7J A;  1MHW A;  2FO5 A;  3KWB X;  1Y08 A;  3M99 A;  2E02 A;  4PAD A;  4X6J A;  3PBH A;  2J7Q C;  2OZ2 A;  3IFU A;  3QT4 A;  3H8B A;  3KSE A;  5CVO B;  1ZIV A;  2JTC A;  2FE8 A;  3KFQ A;  1KFX L;  4X6I A;  1AYW A;  2FRA A;  3P5W A;  4FK5 A;  1ME3 A;  3DF0 A;  1BP4 A;  1CVZ A;  3LXS A;  4N79 A;  3RVX A;  3U8E A;  1STF E;  3N3K A;  2P7U A; 
#chains in the Genus database with same CATH homology
 4FIP A;  4OEL A;  3C9E A;  3O0U A;  2R6N A;  1VSN A;  4BS6 A;  1SNK A;  1X9Y A;  1DEU A;  2HD5 A;  3H7D A;  3MTN A;  1PIP A;  4BSQ A;  1BGO A;  3I3T A;  4CDE B;  3H8C A;  5EF4 A;  3BCN A;  1AU4 A;  3P5U A;  1MIR A;  1AU0 A;  2E00 A;  2BDZ A;  5FPW A;  2G7Y A;  4YYQ A;  2B1M A;  1SP4 B;  6PAD A;  1AU2 A;  3BC3 A;  4BS5 A;  4HWY A;  3P5X A;  1Q6K A;  1BY8 A;  4YYU A;  3H89 A;  4N8W A;  1F2C A;  1Y4H A;  1FH0 A;  1MDW A;  2G8E A;  2CIO A;  1U9X A;  3S3Q A;  1NL6 A;  3WXF A;  4Q8G A;  5K16 A;  1KHQ A;  1CTE A;  2AVW A;  1F2A A;  3ZUA A;  3CBJ A;  1YT7 A;  2DJF B;  1TL9 A;  3PDF A;  3GCB A;  2FQ9 A;  3USV A;  4AXL A;  3N3G A;  4BPV A;  3D9W A;  4NV8 A;  3NHE A;  3BPM A;  1QDQ A;  1PXV A;  3B79 A;  4XR7 A;  3WXG A;  3OIS A;  9PAP A;  1PPD A;  2AUX A;  2F1G A;  1ICF A;  5CVM A;  1CJL A;  3O1G A;  1TLO A;  2VFC A;  2FTD A;  2DCB A;  1EWM A;  1CSB B;  4QRV A;  4I04 A;  1F29 A;  3TNX A;  1AYU A;  4YVA A;  1PAD A;  4MSX A;  4Q8H A;  4PP1 A;  3BOW A;  2DC6 A;  3V6C A;  4KLB A;  1YK8 A;  2OP3 A;  1EWO A;  1AIM A;  3IUT A;  3S3R A;  2NQD B;  1NQC A;  2AYN A;  3PNR A;  2JQF R;  3F75 A;  1PCI A;  2PNS A;  4YV8 A;  4PI3 A;  2B1N A;  2HHN A;  3QJ3 A;  3HD3 A;  2E03 A;  4B55 A;  1CB5 A;  2OUL A;  4BGF A;  2HH5 A;  1PPP A;  1W4T A;  4YYS A;  4XUI A;  1W6F A;  4W4U A;  3OF8 A;  1NLJ A;  1ME4 A;  1JQP A;  2VHF A;  1GMY A;  1M6D A;  5CHT A;  4QBB A;  1GCB A;  2R9F A;  7PCK A;  3KKU A;  3BWK A;  5A24 A;  4N4Z A;  1E2T A;  2DC7 A;  4CZW A;  2PAD A;  3H6S A;  2NQA A;  3K9M A;  4FJC A;  2DC8 A;  1IWD A;  2P0R A;  2DZY A;  1THE A;  1QOL A;  4BQV A;  4ZUX U;  3CH2 X;  3OF9 A;  2XU3 A;  1CS8 A;  2CB5 A;  2AUZ A;  2DCD A;  8PCH A;  1U9W A;  2F7D A;  2NQG A;  3RVW A;  1ATK A;  3KWZ A;  3KX1 A;  2YJ2 A;  5JH3 A;  3LTW A;  4RY2 A;  1MS6 A;  4K7C A;  2E01 A;  2O6X A;  2IBI A;  2R9M A;  2FRQ A;  1KFU L;  2XU4 A;  1DF0 A;  3I06 A;  1CV8 A;  3IOQ A;  2YJB A;  1A6R A;  2GFO A;  4I07 A;  3OVX A;  1F2B A;  1CPJ A;  3K24 A;  1EWP A;  4AXM A;  2BSZ A;  3IHP A;  2G6D A;  1U5I A;  1PBH A;  3E1Z B;  4CDF B;  2ACT A;  1NB5 A;  5JA7 A;  4MZO A;  3HHI A;  3N4C A;  3AI8 A;  4CDD B;  3IMA A;  4W5C A;  4DMX A;  3HWN A;  1NB3 A;  1PPN A;  2FT2 A;  4I05 A;  4P6E A;  2PRE A;  2AU1 A;  4YYW A;  1K3B B;  3D6S A;  1QMY A;  4C5P A;  1GLO A;  1HUC B;  3ERV A;  2VFB A;  1KHP A;  2YJ8 A;  3CH3 X;  1U9Q X;  5F02 A;  4QRG A;  2NQI A;  1BQI A;  2AIM A;  1QXP A;  1YAL A;  3MOR A;  2HXZ A;  3V6E A;  2DCA A;  1AEC A;  4PP2 E;  2FYE A;  1NPZ A;  2R9N A;  2PBH A;  2XU1 A;  2ARY A;  4WA6 A;  4GUZ A;  1ZCM A;  4P6G A;  2DJG B;  4NV7 A;  2IPP B;  3HHA A;  1GEC E;  1PPO A;  2Y5B A;  2AS8 A;  1EWL A;  3PW3 A;  2YJ9 A;  1XKG A;  1MEM A;  3IV2 A;  2VHS A;  1POP A;  1VJV A;  1AYV A;  3IEJ A;  1EF7 A;  1MEG A;  1GX3 A;  5J94 A;  5CHV A;  2AYO A;  1U9V A;  1AU3 A;  2R9C A;  4X6H A;  1S4V A;  2BDL A;  3QSD A;  2DZZ A;  2P86 A;  4MZS A;  1TU6 A;  4DMY A;  3P5V A;  4W5B A;  2ATO A;  1ITO A;  2XU5 A;  5PAD A;  4G54 A;  4QH6 A;  1KXR A;  2R9O A;  2WBF X;  3CBK A;  3LFY A;  3BPF A;  3MHS A;  3KW9 A;  1O0E A;  3WXE A;  3RVV A;  1CQD A;  4QRX A;  5EGW A;  4CDC B;  2FUD A;  2C0Y A;  2YJC A;  4YYR A;  2G8J A;  2DC9 A;  1YK7 A;  2DCC A;  2GHU A;  1PE6 A;  2Y6E A;  3F5V A;  4OEM A;  5CVN B;  2JQG R;  1YVB A;  3OVZ A;  4YYV A;  3K8U A;  3MHH A;  2H7J A;  1MHW A;  2FO5 A;  3KWB X;  1Y08 A;  3M99 A;  2E02 A;  4PAD A;  4X6J A;  3PBH A;  2OZ2 A;  1W5R A;  3QT4 A;  3H8B A;  3KSE A;  5CVO B;  1ZIV A;  3KFQ A;  1KFX L;  4X6I A;  1AYW A;  2FRA A;  3P5W A;  4FK5 A;  1ME3 A;  3DF0 A;  1BP4 A;  1CVZ A;  3LXS A;  4N79 A;  3RVX A;  3U8E A;  1STF E;  3N3K A;  2P7U A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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