1KXRA

Crystal structure of calcium-bound protease core of calpain i
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
320
structure length
320
Chain Sequence
b'NAIKYLGQDYENLRARCLQNGVLFQDDAFPPVSHSLGFKELGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDSWLLAAIASLTLNETILHRVVPYGQSFQEGYAGIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHSAQGNEFWSALLEKAYAKVNGSYEALSGGCTSEAFEDFTGGVTEWYDLQKAPSDLYQIILKALERGSLLGCSINISDIRDLEAITFKNLVRGHAYSVTDAKQVTYQGQRVNLIRMRNPWGEVEWKGPWSDNSYEWNKVDPYEREQLRVKMEDGEFWMSFRDFIREFTKLEICN'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords thiol protease DOMAINS I AND II
publication title A Ca(2+) switch aligns the active site of calpain.
pubmed doi rcsb
source organism Rattus norvegicus
molecule tags Hydrolase
total genus 96
structure length 320
sequence length 320
chains with identical sequence B
ec nomenclature ec 3.4.22.52: Calpain-1.
pdb deposition date 2002-02-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00648 Peptidase_C2 Calpain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1kxrA02
1MHWA 3K9MA 4P6EA 3BWKA 4YVAA 1U9QX 3KFQA 3I3TA 2F1GA 4YYSA 4I07A 1AU0A 8PCHA 2XU3A 1ZIVA 1A6RA 1AU4A 3WXEA 2AUZA 2FYEA 4Q8HA 4G54A 1STFE 2YJ2A 4BS6A 1TL9A 4K7CA 4HWYA 4CDEB 3P5XA 4MSXA 1ZCMA 3OISA 2R9CA 2AVWA 3MORA 1SP4B 3KWZA 2XU1A 3E1ZB 3AI8A 1CTEA 3I06A 3KX1A 5PADA 1CQDA 2FUDA 1FH0A 1QDQA 2VHFA 3CBJA 3H6SA 1QMYA 4W5BA 4W5CA 3F5VA 4FIPA 1PCIA 2DZYA 1U9XA 3KWBX 2IPPB 2DZZA 4YYQA 2YJ9A 1NB3A 4XUIA 2PADA 3IUTA 3OF9A 1BGOA 1PPDA 4XR7A 3KSEA 3IEJA 4YYUA 3BCNA 1U5IA 3IOQA 3N3GA 2VHSA 4W4UA 1PPPA 2Y5BA 4OELA 3U8EA 3LXSA 3QJ3A 1AECA 1EWOA 1DEUA 1ME4A 1MEMA 1U9WA 2DCBA 1PPOA 3F75A 4X6JA 3RVWA 5J94A 2FO5A 3DF0A 3IMAA 4YYWA 2DC6A 1MS6A 3O1GA 2IBIA 1BP4A 2CB5A 4X6HA 1CB5A 1QXPA 1AIMA 1AU2A 1AYWA 2G7YA 1M6DA 2O6XA 3ZUAA 5JH3A 2DC7A 3BOWA 3N4CA 1GLOA 2F7DA 3MTNA 2PNSA 4QRXA 4QH6A 1AYUA 3NHEA 1NB5A 3V6CA 1KHQA 3OVXA 3HHAA 1JQPA 2G6DA 2YJ8A 1MIRA 2JQGR 4RY2A 2DJGB 4ZUXU 4OEMA 3QSDA 1EWLA 5CHVA 4PI3A 2R9FA 1X9YA 5F02A 2FRQA 3BPMA 1MDWA 1GECE 2PBHA 3H89A 4DMXA 2AU1A 3RVVA 1F29A 1XKGA 2ARYA 4BSQA 4YYRA 1PIPA 3H8BA 5FPWA 2DCCA 2Y6EA 1QOLA 1AYVA 2CIOA 2G8JA 4FK5A 2NQGA 7PCKA 1PADA 1CS8A 2DJFB 4BS5A 5EGWA 3USVA 1ATKA 3IV2A 4QRVA 3D6SA 1EF7A 2FT2A 3V6EA 1PPNA 2WBFX 1Y4HA 1EWMA 1KFUL 3P5WA 1TU6A 3OF8A 3CH2X 3S3QA 3ERVA 1Q6KA 2G8EA 5A24A 2HXZA 2FQ9A 2E00A 1CVZA 3K8UA 1ITOA 2AS8A 2C0YA 1VJVA 2DC9A 1VSNA 3HHIA 1AU3A 3IHPA 4PADA 2B1NA 4MZOA 2OP3A 1HUCB 2FRAA 3CBKA 1YVBA 3N3KA 3PDFA 3MHHA 3KW9A 3S3RA 1YALA 2E01A 2PREA 2NQAA 1PXVA 3HWNA 1YK8A 2OZ2A 2DCDA 3CH3X 2E03A 2R9NA 5JA7A 1NPZA 2P86A 1NQCA 4QBBA 1Y08A 2R6NA 1SNKA 1KFXL 1PE6A 3H7DA 4N4ZA 4YYVA 2P0RA 1CSBB 3B79A 1NL6A 5EF4A 1NLJA 2XU5A 4KLBA 3PBHA 5CHTA 1GCBA 1U9VA 1IWDA 1TLOA 1CV8A 3RVXA 1O0EA 1F2CA 2BDLA 3K24A 1YK7A 3PNRA 2DC8A 3H8CA 1MEGA 3PW3A 2HHNA 1EWPA 1CPJA 4CDFB 4YV8A 2ACTA 2E02A 1F2BA 1KXRA 1KHPA 2HH5A 1CJLA 4CZWA 4FJCA 3WXFA 1F2AA 2NQDB 2H7JA 3HD3A 4AXLA 4I05A 1BY8A 3TNXA 2R9OA 4BQVA 2FTDA 6PADA 1PBHA 2ATOA 3P5UA 3MHSA 1BQIA 2XU4A 4WA6A 1POPA 4AXMA 2OULA 2P7UA 5CVNB 5CVOB 3BPFA 4MZSA 1YT7A 1K3BB 2JQFR 9PAPA 1THEA 4Q8GA 2GFOA 4X6IA 1GMYA 3O0UA 2B1MA 4BPVA 3C9EA 2R9MA 3KKUA 3WXGA 2GHUA 3GCBA 2BDZA 1DF0A 2HD5A 4QRGA 1ICFA 4I04A 4N79A 4PP2E 5CVMA 4CDDB 2DCAA 2AYOA 3P5VA 4P6GA 3OVZA 2AIMA 2AYNA 4CDCB 2YJCA 3QT4A 4PP1A 2AUXA 4N8WA 2NQIA 3M99A 3LFYA 1S4VA 1ME3A 5K16A 4DMYA 2YJBA 3BC3A
chains in the Genus database with same CATH superfamily
1MHWA 3K9MA 4P6EA 3BWKA 4YVAA 1U9QX 3KFQA 3I3TA 2J7QC 4BOSA 2F1GA 4YYSA 4I07A 1AU0A 8PCHA 2XU3A 1ZIVA 1A6RA 1AU4A 3WXEA 2AUZA 2FYEA 4BOPA 2JTCA 4Q8HA 4G54A 1STFE 4OW0A 2YJ2A 4BS6A 1TL9A 4K7CA 4RKXA 4A5UA 4HWYA 4CDEB 2Z84A 3P5XA 4MSXA 1ZCMA 3OISA 2R9CA 2AVWA 3MORA 1SP4B 3KWZA 2XU1A 3E1ZB 3AI8A 1CTEA 3I06A 3KX1A 5PADA 1CQDA 2FUDA 1FH0A 1QDQA 2VHFA 3CBJA 3H6SA 1QMYA 4W5BA 4W5CA 3F5VA 4FIPA 1PCIA 4RF1A 2DZYA 4OVZA 1U9XA 3KWBX 2IPPB 2DZZA 2UZJA 4YYQA 5E6JA 2YJ9A 1NB3A 4XUIA 2PADA 3O65A 3IUTA 3OF9A 1BGOA 1PPDA 4XR7A 3KSEA 1UKFA 3IEJA 4YYUA 3BCNA 3PHUA 1U5IA 3IOQA 3N3GA 2VHSA 4W4UA 2HWKA 1PPPA 2Y5BA 4OELA 3U8EA 3LXSA 1AECA 1EWOA 3QJ3A 1DEUA 1ME4A 1MEMA 1U9WA 4IP3A 2DCBA 4BOUA 1PPOA 3F75A 4X6JA 3RVWA 2FE8A 5J94A 2FO5A 3DF0A 3IMAA 4YYWA 2DC6A 1MS6A 3O1GA 2IBIA 4MM3B 2BU3A 1BP4A 2CB5A 3BBAA 4X6HA 1CB5A 1PVJA 1QXPA 1AIMA 1AU2A 1AYWA 2G7YA 4REZA 1M6DA 2O6XA 3ZUAA 5JH3A 2DC7A 3BOWA 3N4CA 1GLOA 3TRKA 3PT2A 2F7DA 4HXDB 3MTNA 2PNSA 2JRIA 4QRXA 4QH6A 1AYUA 3NHEA 3PHXA 1NB5A 3V6CA 1KHQA 3OVXA 3HHAA 1JQPA 2G6DA 3C0RA 2YJ8A 1MIRA 2JQGR 4RY2A 2DJGB 4ZUXU 4OEMA 3QSDA 4ZTBA 1EWLA 3BY4A 5CHVA 4PI3A 2R9FA 1X9YA 5F02A 2FRQA 3BPMA 1MDWA 1GECE 2PBHA 2DOSA 3H89A 4DMXA 2AU1A 3RVVA 1F29A 1XKGA 2ARYA 4BSQA 4YYRA 1PIPA 3H8BA 4D8EA 5FPWA 3B21A 2DCCA 2Y6EA 3IFUA 1QOLA 1AYVA 2CIOA 2G8JA 4FK5A 5JZEA 2NQGA 7PCKA 1PADA 3W31A 1CS8A 2DJFB 4BS5A 5EGWA 3USVA 4RF0A 1ATKA 3IV2A 4QRVA 3D6SA 1EF7A 2FT2A 3V6EA 5KO3A 4P16A 1PPNA 2WBFX 1Y4HA 1EWMA 4OVZB 1KFUL 3P5WA 1TU6A 3OF8A 3CH2X 3S3QA 3ERVA 5EZQA 2BTWA 1Q6KA 2G8EA 4WURA 3PRMA 5A24A 1DKIA 2HXZA 4BOZA 2FQ9A 2E00A 1CVZA 3K8UA 1ITOA 4RNAA 2AS8A 2C0YA 1VJVA 2DC9A 1VSNA 3HHIA 1AU3A 3IHPA 4PADA 2B1NA 4GUAA 4MZOA 3MJ5A 2OP3A 1HUCB 2FRAA 3CBKA 1YVBA 3N3KA 3PDFA 3MHHA 3KW9A 3S3RA 4BOQA 1YALA 2E01A 2PREA 2NQAA 1PXVA 3HWNA 1YK8A 2OZ2A 2DCDA 4D8BA 3CH3X 2E03A 2R9NA 5JA7A 1NPZA 2P86A 1NQCA 4QBBA 1Y08A 2R6NA 3W30A 1SNKA 1KFXL 1PE6A 3H7DA 4N4ZA 4YYVA 3E9SA 2P0RA 1CSBB 3B79A 1NL6A 5EF4A 1NLJA 2AGAA 2XU5A 4KLBA 4XZXA 3PBHA 5CHTA 1GCBA 1U9VA 1IWDA 1TLOA 3OQCA 1CV8A 3RVXA 1O0EA 4MI7A 3MTVA 1F2CA 2BDLA 3K24A 1YK7A 3PNRA 2DC8A 3H8CA 1MEGA 3PW3A 2HHNA 1EWPA 3TMPA 1CPJA 4CDFB 4YV8A 3ZNHA 2ACTA 2E02A 1F2BA 1KXRA 1KHPA 3PHWA 2HH5A 1CJLA 4CZWA 4FJCA 3WXFA 1F2AA 2NQDB 2H7JA 3HD3A 4AXLA 4I05A 1BY8A 3TNXA 2R9OA 4BQVA 2BTWB 2FTDA 6PADA 1PBHA 2ATOA 3P5UA 4R3DA 3MHSA 1BQIA 2XU4A 1YZBA 4WA6A 1POPA 4AXMA 2OULA 2P7UA 5CVNB 3MP2A 5CVOB 3BPFA 4MZSA 1YT7A 1K3BB 2JQFR 9PAPA 1THEA 4Q8GA 2GFOA 4M0WA 4X6IA 1GMYA 3O0UA 2B1MA 4BPVA 3C9EA 2R9MA 3KKUA 3WXGA 2GHUA 3GCBA 2BDZA 1DF0A 2HD5A 4QRGA 1ICFA 4I04A 4N79A 4PP2E 5CVMA 3PRPA 4CDDB 4PT5A 2DCAA 2AYOA 3P5VA 4P6GA 3OVZA 2AIMA 2AYNA 4CDCB 2YJCA 3QT4A 4D8IA 4PP1A 5EZSA 3RNVA 2AUXA 4N8WA 2NQIA 2J7QA 3BB7A 3M99A 3LFYA 1S4VA 1ME3A 3PSEA 5K16A 4IUMA 4DMYA 2YJBA 3BC3A
chains in the Genus database with same CATH topology
1MHWA 3K9MA 2BSZA 4P6EA 4BGFA 3BWKA 4YVAA 1U9QX 3KFQA 3I3TA 2F1GA 4YYSA 4I07A 1AU0A 8PCHA 2XU3A 1ZIVA 1A6RA 1AU4A 3WXEA 2AUZA 2FYEA 4Q8HA 4G54A 1STFE 2YJ2A 4C5PA 4BS6A 1TL9A 4K7CA 4HWYA 4CDEB 3P5XA 4MSXA 1ZCMA 3OISA 2R9CA 2AVWA 3MORA 1SP4B 3KWZA 2XU1A 3E1ZB 3AI8A 1CTEA 3I06A 3KX1A 5PADA 1CQDA 2FUDA 1FH0A 1QDQA 2VHFA 3CBJA 3H6SA 1QMYA 4W5BA 4W5CA 3F5VA 4NV8A 4FIPA 1PCIA 2DZYA 1U9XA 4GUZA 3KWBX 2IPPB 2DZZA 4YYQA 2YJ9A 1NB3A 4XUIA 2PADA 3IUTA 3OF9A 1BGOA 1PPDA 4XR7A 3KSEA 3IEJA 4YYUA 3BCNA 1U5IA 3IOQA 3N3GA 2VHSA 4W4UA 1PPPA 2Y5BA 4OELA 3U8EA 3LXSA 3QJ3A 1AECA 1EWOA 1DEUA 1ME4A 1MEMA 1U9WA 2DCBA 1W6FA 1PPOA 3F75A 4X6JA 3RVWA 5J94A 2FO5A 3DF0A 3IMAA 4YYWA 2DC6A 1MS6A 3O1GA 2IBIA 1BP4A 2CB5A 4X6HA 1CB5A 1QXPA 1AIMA 1AU2A 1AYWA 2G7YA 1M6DA 2O6XA 3ZUAA 5JH3A 2DC7A 3BOWA 3N4CA 1GLOA 3D9WA 2F7DA 3MTNA 2PNSA 4QRXA 4QH6A 1AYUA 3NHEA 1NB5A 3V6CA 1KHQA 3OVXA 3HHAA 1JQPA 2G6DA 2YJ8A 1MIRA 2JQGR 4RY2A 2DJGB 4ZUXU 4OEMA 3QSDA 1EWLA 5CHVA 4PI3A 2R9FA 1X9YA 5F02A 2FRQA 3BPMA 1MDWA 1GECE 2PBHA 3H89A 4DMXA 2AU1A 3RVVA 1F29A 1XKGA 2ARYA 4BSQA 4YYRA 1PIPA 3H8BA 5FPWA 2DCCA 2Y6EA 3LTWA 1QOLA 1AYVA 2CIOA 2G8JA 4FK5A 2NQGA 7PCKA 1PADA 1CS8A 2DJFB 4BS5A 5EGWA 3USVA 1ATKA 3IV2A 4QRVA 3D6SA 1EF7A 2FT2A 3V6EA 1PPNA 2WBFX 1Y4HA 1EWMA 1KFUL 3P5WA 4NV7A 1TU6A 3OF8A 3CH2X 3S3QA 3ERVA 1Q6KA 2G8EA 1W4TA 5A24A 2HXZA 2FQ9A 2E00A 1CVZA 3K8UA 1ITOA 4B55A 2AS8A 2C0YA 1VJVA 2DC9A 1VSNA 3HHIA 1AU3A 3IHPA 4PADA 2B1NA 4MZOA 2OP3A 1HUCB 2FRAA 3CBKA 1YVBA 3N3KA 3PDFA 3MHHA 3KW9A 3S3RA 1YALA 2E01A 2PREA 2NQAA 1PXVA 3HWNA 1YK8A 2OZ2A 2DCDA 3CH3X 2E03A 2R9NA 5JA7A 1NPZA 2P86A 1NQCA 4QBBA 1Y08A 2R6NA 1SNKA 1KFXL 1PE6A 3H7DA 4N4ZA 4YYVA 2P0RA 1CSBB 1W5RA 3B79A 1NL6A 5EF4A 2VFBA 1NLJA 2XU5A 4KLBA 3PBHA 5CHTA 1GCBA 1U9VA 1IWDA 1TLOA 1CV8A 3RVXA 1O0EA 1F2CA 2BDLA 3K24A 1GX3A 1YK7A 3PNRA 2DC8A 3H8CA 1MEGA 3PW3A 2HHNA 1EWPA 1CPJA 4CDFB 4YV8A 2ACTA 2E02A 1F2BA 1KXRA 1KHPA 2HH5A 1CJLA 4CZWA 4FJCA 3WXFA 1F2AA 2NQDB 2H7JA 3HD3A 2VFCA 4AXLA 4I05A 1BY8A 3TNXA 2R9OA 4BQVA 2FTDA 6PADA 1PBHA 2ATOA 3P5UA 3MHSA 1BQIA 2XU4A 4WA6A 1POPA 1E2TA 4AXMA 2OULA 2P7UA 5CVNB 5CVOB 3BPFA 4MZSA 1YT7A 1K3BB 2JQFR 9PAPA 1THEA 4Q8GA 2GFOA 4X6IA 1GMYA 3O0UA 2B1MA 4BPVA 3C9EA 2R9MA 3KKUA 3WXGA 2GHUA 3GCBA 2BDZA 1DF0A 2HD5A 4QRGA 1ICFA 4I04A 4N79A 4PP2E 5CVMA 4CDDB 2DCAA 2AYOA 3P5VA 4P6GA 3OVZA 2AIMA 2AYNA 4CDCB 2YJCA 3QT4A 4PP1A 2AUXA 4N8WA 2NQIA 3M99A 3LFYA 1S4VA 1ME3A 5K16A 4DMYA 2YJBA 3BC3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1MHW A;  3K9M A;  4P6E A;  3BWK A;  4YVA A;  1U9Q X;  3KFQ A;  3I3T A;  2F1G A;  4YYS A;  4I07 A;  1AU0 A;  8PCH A;  2XU3 A;  1ZIV A;  1A6R A;  1AU4 A;  3WXE A;  2AUZ A;  2FYE A;  4Q8H A;  4G54 A;  1STF E;  2YJ2 A;  4BS6 A;  1TL9 A;  4K7C A;  4HWY A;  4CDE B;  3P5X A;  4MSX A;  1ZCM A;  3OIS A;  2R9C A;  2AVW A;  3MOR A;  1SP4 B;  3KWZ A;  2XU1 A;  3E1Z B;  3AI8 A;  1CTE A;  3I06 A;  3KX1 A;  5PAD A;  1CQD A;  2FUD A;  1FH0 A;  1QDQ A;  2VHF A;  3CBJ A;  3H6S A;  1QMY A;  4W5B A;  4W5C A;  3F5V A;  4FIP A;  1PCI A;  2DZY A;  1U9X A;  3KWB X;  2IPP B;  2DZZ A;  4YYQ A;  2YJ9 A;  1NB3 A;  4XUI A;  2PAD A;  3IUT A;  3OF9 A;  1BGO A;  1PPD A;  4XR7 A;  3KSE A;  3IEJ A;  4YYU A;  3BCN A;  1U5I A;  3IOQ A;  3N3G A;  2VHS A;  4W4U A;  1PPP A;  2Y5B A;  4OEL A;  3U8E A;  3LXS A;  3QJ3 A;  1AEC A;  1EWO A;  1DEU A;  1ME4 A;  1MEM A;  1U9W A;  2DCB A;  1PPO A;  3F75 A;  4X6J A;  3RVW A;  5J94 A;  2FO5 A;  3DF0 A;  3IMA A;  4YYW A;  2DC6 A;  1MS6 A;  3O1G A;  2IBI A;  1BP4 A;  2CB5 A;  4X6H A;  1CB5 A;  1QXP A;  1AIM A;  1AU2 A;  1AYW A;  2G7Y A;  1M6D A;  2O6X A;  3ZUA A;  5JH3 A;  2DC7 A;  3BOW A;  3N4C A;  1GLO A;  2F7D A;  3MTN A;  2PNS A;  4QRX A;  4QH6 A;  1AYU A;  3NHE A;  1NB5 A;  3V6C A;  1KHQ A;  3OVX A;  3HHA A;  1JQP A;  2G6D A;  2YJ8 A;  1MIR A;  2JQG R;  4RY2 A;  2DJG B;  4ZUX U;  4OEM A;  3QSD A;  1EWL A;  5CHV A;  4PI3 A;  2R9F A;  1X9Y A;  5F02 A;  2FRQ A;  3BPM A;  1MDW A;  1GEC E;  2PBH A;  3H89 A;  4DMX A;  2AU1 A;  3RVV A;  1F29 A;  1XKG A;  2ARY A;  4BSQ A;  4YYR A;  1PIP A;  3H8B A;  5FPW A;  2DCC A;  2Y6E A;  1QOL A;  1AYV A;  2CIO A;  2G8J A;  4FK5 A;  2NQG A;  7PCK A;  1PAD A;  1CS8 A;  2DJF B;  4BS5 A;  5EGW A;  3USV A;  1ATK A;  3IV2 A;  4QRV A;  3D6S A;  1EF7 A;  2FT2 A;  3V6E A;  1PPN A;  2WBF X;  1Y4H A;  1EWM A;  1KFU L;  3P5W A;  1TU6 A;  3OF8 A;  3CH2 X;  3S3Q A;  3ERV A;  1Q6K A;  2G8E A;  5A24 A;  2HXZ A;  2FQ9 A;  2E00 A;  1CVZ A;  3K8U A;  1ITO A;  2AS8 A;  2C0Y A;  1VJV A;  2DC9 A;  1VSN A;  3HHI A;  1AU3 A;  3IHP A;  4PAD A;  2B1N A;  4MZO A;  2OP3 A;  1HUC B;  2FRA A;  3CBK A;  1YVB A;  3N3K A;  3PDF A;  3MHH A;  3KW9 A;  3S3R A;  1YAL A;  2E01 A;  2PRE A;  2NQA A;  1PXV A;  3HWN A;  1YK8 A;  2OZ2 A;  2DCD A;  3CH3 X;  2E03 A;  2R9N A;  5JA7 A;  1NPZ A;  2P86 A;  1NQC A;  4QBB A;  1Y08 A;  2R6N A;  1SNK A;  1KFX L;  1PE6 A;  3H7D A;  4N4Z A;  4YYV A;  2P0R A;  1CSB B;  3B79 A;  1NL6 A;  5EF4 A;  1NLJ A;  2XU5 A;  4KLB A;  3PBH A;  5CHT A;  1GCB A;  1U9V A;  1IWD A;  1TLO A;  1CV8 A;  3RVX A;  1O0E A;  1F2C A;  2BDL A;  3K24 A;  1YK7 A;  3PNR A;  2DC8 A;  3H8C A;  1MEG A;  3PW3 A;  2HHN A;  1EWP A;  1CPJ A;  4CDF B;  4YV8 A;  2ACT A;  2E02 A;  1F2B A;  1KXR A;  1KHP A;  2HH5 A;  1CJL A;  4CZW A;  4FJC A;  3WXF A;  1F2A A;  2NQD B;  2H7J A;  3HD3 A;  4AXL A;  4I05 A;  1BY8 A;  3TNX A;  2R9O A;  4BQV A;  2FTD A;  6PAD A;  1PBH A;  2ATO A;  3P5U A;  3MHS A;  1BQI A;  2XU4 A;  4WA6 A;  1POP A;  4AXM A;  2OUL A;  2P7U A;  5CVN B;  5CVO B;  3BPF A;  4MZS A;  1YT7 A;  1K3B B;  2JQF R;  9PAP A;  1THE A;  4Q8G A;  2GFO A;  4X6I A;  1GMY A;  3O0U A;  2B1M A;  4BPV A;  3C9E A;  2R9M A;  3KKU A;  3WXG A;  2GHU A;  3GCB A;  2BDZ A;  1DF0 A;  2HD5 A;  4QRG A;  1ICF A;  4I04 A;  4N79 A;  4PP2 E;  5CVM A;  4CDD B;  2DCA A;  2AYO A;  3P5V A;  4P6G A;  3OVZ A;  2AIM A;  2AYN A;  4CDC B;  2YJC A;  3QT4 A;  4PP1 A;  2AUX A;  4N8W A;  2NQI A;  3M99 A;  3LFY A;  1S4V A;  1ME3 A;  5K16 A;  4DMY A;  2YJB A;  3BC3 A; 
#chains in the Genus database with same CATH topology
 1MHW A;  3K9M A;  4P6E A;  3BWK A;  4YVA A;  1U9Q X;  3KFQ A;  3I3T A;  2J7Q C;  4BOS A;  2F1G A;  4YYS A;  4I07 A;  1AU0 A;  8PCH A;  2XU3 A;  1ZIV A;  1A6R A;  1AU4 A;  3WXE A;  2AUZ A;  2FYE A;  4BOP A;  2JTC A;  4Q8H A;  4G54 A;  1STF E;  4OW0 A;  2YJ2 A;  4BS6 A;  1TL9 A;  4K7C A;  4RKX A;  4A5U A;  4HWY A;  4CDE B;  2Z84 A;  3P5X A;  4MSX A;  1ZCM A;  3OIS A;  2R9C A;  2AVW A;  3MOR A;  1SP4 B;  3KWZ A;  2XU1 A;  3E1Z B;  3AI8 A;  1CTE A;  3I06 A;  3KX1 A;  5PAD A;  1CQD A;  2FUD A;  1FH0 A;  1QDQ A;  2VHF A;  3CBJ A;  3H6S A;  1QMY A;  4W5B A;  4W5C A;  3F5V A;  4FIP A;  1PCI A;  4RF1 A;  2DZY A;  4OVZ A;  1U9X A;  3KWB X;  2IPP B;  2DZZ A;  2UZJ A;  4YYQ A;  5E6J A;  2YJ9 A;  1NB3 A;  4XUI A;  2PAD A;  3O65 A;  3IUT A;  3OF9 A;  1BGO A;  1PPD A;  4XR7 A;  3KSE A;  1UKF A;  3IEJ A;  4YYU A;  3BCN A;  3PHU A;  1U5I A;  3IOQ A;  3N3G A;  2VHS A;  4W4U A;  2HWK A;  1PPP A;  2Y5B A;  4OEL A;  3U8E A;  3LXS A;  1AEC A;  1EWO A;  3QJ3 A;  1DEU A;  1ME4 A;  1MEM A;  1U9W A;  4IP3 A;  2DCB A;  4BOU A;  1PPO A;  3F75 A;  4X6J A;  3RVW A;  2FE8 A;  5J94 A;  2FO5 A;  3DF0 A;  3IMA A;  4YYW A;  2DC6 A;  1MS6 A;  3O1G A;  2IBI A;  4MM3 B;  2BU3 A;  1BP4 A;  2CB5 A;  3BBA A;  4X6H A;  1CB5 A;  1PVJ A;  1QXP A;  1AIM A;  1AU2 A;  1AYW A;  2G7Y A;  4REZ A;  1M6D A;  2O6X A;  3ZUA A;  5JH3 A;  2DC7 A;  3BOW A;  3N4C A;  1GLO A;  3TRK A;  3PT2 A;  2F7D A;  4HXD B;  3MTN A;  2PNS A;  2JRI A;  4QRX A;  4QH6 A;  1AYU A;  3NHE A;  3PHX A;  1NB5 A;  3V6C A;  1KHQ A;  3OVX A;  3HHA A;  1JQP A;  2G6D A;  3C0R A;  2YJ8 A;  1MIR A;  2JQG R;  4RY2 A;  2DJG B;  4ZUX U;  4OEM A;  3QSD A;  4ZTB A;  1EWL A;  3BY4 A;  5CHV A;  4PI3 A;  2R9F A;  1X9Y A;  5F02 A;  2FRQ A;  3BPM A;  1MDW A;  1GEC E;  2PBH A;  2DOS A;  3H89 A;  4DMX A;  2AU1 A;  3RVV A;  1F29 A;  1XKG A;  2ARY A;  4BSQ A;  4YYR A;  1PIP A;  3H8B A;  4D8E A;  5FPW A;  3B21 A;  2DCC A;  2Y6E A;  3IFU A;  1QOL A;  1AYV A;  2CIO A;  2G8J A;  4FK5 A;  5JZE A;  2NQG A;  7PCK A;  1PAD A;  3W31 A;  1CS8 A;  2DJF B;  4BS5 A;  5EGW A;  3USV A;  4RF0 A;  1ATK A;  3IV2 A;  4QRV A;  3D6S A;  1EF7 A;  2FT2 A;  3V6E A;  5KO3 A;  4P16 A;  1PPN A;  2WBF X;  1Y4H A;  1EWM A;  4OVZ B;  1KFU L;  3P5W A;  1TU6 A;  3OF8 A;  3CH2 X;  3S3Q A;  3ERV A;  5EZQ A;  2BTW A;  1Q6K A;  2G8E A;  4WUR A;  3PRM A;  5A24 A;  1DKI A;  2HXZ A;  4BOZ A;  2FQ9 A;  2E00 A;  1CVZ A;  3K8U A;  1ITO A;  4RNA A;  2AS8 A;  2C0Y A;  1VJV A;  2DC9 A;  1VSN A;  3HHI A;  1AU3 A;  3IHP A;  4PAD A;  2B1N A;  4GUA A;  4MZO A;  3MJ5 A;  2OP3 A;  1HUC B;  2FRA A;  3CBK A;  1YVB A;  3N3K A;  3PDF A;  3MHH A;  3KW9 A;  3S3R A;  4BOQ A;  1YAL A;  2E01 A;  2PRE A;  2NQA A;  1PXV A;  3HWN A;  1YK8 A;  2OZ2 A;  2DCD A;  4D8B A;  3CH3 X;  2E03 A;  2R9N A;  5JA7 A;  1NPZ A;  2P86 A;  1NQC A;  4QBB A;  1Y08 A;  2R6N A;  3W30 A;  1SNK A;  1KFX L;  1PE6 A;  3H7D A;  4N4Z A;  4YYV A;  3E9S A;  2P0R A;  1CSB B;  3B79 A;  1NL6 A;  5EF4 A;  1NLJ A;  2AGA A;  2XU5 A;  4KLB A;  4XZX A;  3PBH A;  5CHT A;  1GCB A;  1U9V A;  1IWD A;  1TLO A;  3OQC A;  1CV8 A;  3RVX A;  1O0E A;  4MI7 A;  3MTV A;  1F2C A;  2BDL A;  3K24 A;  1YK7 A;  3PNR A;  2DC8 A;  3H8C A;  1MEG A;  3PW3 A;  2HHN A;  1EWP A;  3TMP A;  1CPJ A;  4CDF B;  4YV8 A;  3ZNH A;  2ACT A;  2E02 A;  1F2B A;  1KXR A;  1KHP A;  3PHW A;  2HH5 A;  1CJL A;  4CZW A;  4FJC A;  3WXF A;  1F2A A;  2NQD B;  2H7J A;  3HD3 A;  4AXL A;  4I05 A;  1BY8 A;  3TNX A;  2R9O A;  4BQV A;  2BTW B;  2FTD A;  6PAD A;  1PBH A;  2ATO A;  3P5U A;  4R3D A;  3MHS A;  1BQI A;  2XU4 A;  1YZB A;  4WA6 A;  1POP A;  4AXM A;  2OUL A;  2P7U A;  5CVN B;  3MP2 A;  5CVO B;  3BPF A;  4MZS A;  1YT7 A;  1K3B B;  2JQF R;  9PAP A;  1THE A;  4Q8G A;  2GFO A;  4M0W A;  4X6I A;  1GMY A;  3O0U A;  2B1M A;  4BPV A;  3C9E A;  2R9M A;  3KKU A;  3WXG A;  2GHU A;  3GCB A;  2BDZ A;  1DF0 A;  2HD5 A;  4QRG A;  1ICF A;  4I04 A;  4N79 A;  4PP2 E;  5CVM A;  3PRP A;  4CDD B;  4PT5 A;  2DCA A;  2AYO A;  3P5V A;  4P6G A;  3OVZ A;  2AIM A;  2AYN A;  4CDC B;  2YJC A;  3QT4 A;  4D8I A;  4PP1 A;  5EZS A;  3RNV A;  2AUX A;  4N8W A;  2NQI A;  2J7Q A;  3BB7 A;  3M99 A;  3LFY A;  1S4V A;  1ME3 A;  3PSE A;  5K16 A;  4IUM A;  4DMY A;  2YJB A;  3BC3 A; 
#chains in the Genus database with same CATH homology
 1MHW A;  3K9M A;  2BSZ A;  4P6E A;  4BGF A;  3BWK A;  4YVA A;  1U9Q X;  3KFQ A;  3I3T A;  2F1G A;  4YYS A;  4I07 A;  1AU0 A;  8PCH A;  2XU3 A;  1ZIV A;  1A6R A;  1AU4 A;  3WXE A;  2AUZ A;  2FYE A;  4Q8H A;  4G54 A;  1STF E;  2YJ2 A;  4C5P A;  4BS6 A;  1TL9 A;  4K7C A;  4HWY A;  4CDE B;  3P5X A;  4MSX A;  1ZCM A;  3OIS A;  2R9C A;  2AVW A;  3MOR A;  1SP4 B;  3KWZ A;  2XU1 A;  3E1Z B;  3AI8 A;  1CTE A;  3I06 A;  3KX1 A;  5PAD A;  1CQD A;  2FUD A;  1FH0 A;  1QDQ A;  2VHF A;  3CBJ A;  3H6S A;  1QMY A;  4W5B A;  4W5C A;  3F5V A;  4NV8 A;  4FIP A;  1PCI A;  2DZY A;  1U9X A;  4GUZ A;  3KWB X;  2IPP B;  2DZZ A;  4YYQ A;  2YJ9 A;  1NB3 A;  4XUI A;  2PAD A;  3IUT A;  3OF9 A;  1BGO A;  1PPD A;  4XR7 A;  3KSE A;  3IEJ A;  4YYU A;  3BCN A;  1U5I A;  3IOQ A;  3N3G A;  2VHS A;  4W4U A;  1PPP A;  2Y5B A;  4OEL A;  3U8E A;  3LXS A;  3QJ3 A;  1AEC A;  1EWO A;  1DEU A;  1ME4 A;  1MEM A;  1U9W A;  2DCB A;  1W6F A;  1PPO A;  3F75 A;  4X6J A;  3RVW A;  5J94 A;  2FO5 A;  3DF0 A;  3IMA A;  4YYW A;  2DC6 A;  1MS6 A;  3O1G A;  2IBI A;  1BP4 A;  2CB5 A;  4X6H A;  1CB5 A;  1QXP A;  1AIM A;  1AU2 A;  1AYW A;  2G7Y A;  1M6D A;  2O6X A;  3ZUA A;  5JH3 A;  2DC7 A;  3BOW A;  3N4C A;  1GLO A;  3D9W A;  2F7D A;  3MTN A;  2PNS A;  4QRX A;  4QH6 A;  1AYU A;  3NHE A;  1NB5 A;  3V6C A;  1KHQ A;  3OVX A;  3HHA A;  1JQP A;  2G6D A;  2YJ8 A;  1MIR A;  2JQG R;  4RY2 A;  2DJG B;  4ZUX U;  4OEM A;  3QSD A;  1EWL A;  5CHV A;  4PI3 A;  2R9F A;  1X9Y A;  5F02 A;  2FRQ A;  3BPM A;  1MDW A;  1GEC E;  2PBH A;  3H89 A;  4DMX A;  2AU1 A;  3RVV A;  1F29 A;  1XKG A;  2ARY A;  4BSQ A;  4YYR A;  1PIP A;  3H8B A;  5FPW A;  2DCC A;  2Y6E A;  3LTW A;  1QOL A;  1AYV A;  2CIO A;  2G8J A;  4FK5 A;  2NQG A;  7PCK A;  1PAD A;  1CS8 A;  2DJF B;  4BS5 A;  5EGW A;  3USV A;  1ATK A;  3IV2 A;  4QRV A;  3D6S A;  1EF7 A;  2FT2 A;  3V6E A;  1PPN A;  2WBF X;  1Y4H A;  1EWM A;  1KFU L;  3P5W A;  4NV7 A;  1TU6 A;  3OF8 A;  3CH2 X;  3S3Q A;  3ERV A;  1Q6K A;  2G8E A;  1W4T A;  5A24 A;  2HXZ A;  2FQ9 A;  2E00 A;  1CVZ A;  3K8U A;  1ITO A;  4B55 A;  2AS8 A;  2C0Y A;  1VJV A;  2DC9 A;  1VSN A;  3HHI A;  1AU3 A;  3IHP A;  4PAD A;  2B1N A;  4MZO A;  2OP3 A;  1HUC B;  2FRA A;  3CBK A;  1YVB A;  3N3K A;  3PDF A;  3MHH A;  3KW9 A;  3S3R A;  1YAL A;  2E01 A;  2PRE A;  2NQA A;  1PXV A;  3HWN A;  1YK8 A;  2OZ2 A;  2DCD A;  3CH3 X;  2E03 A;  2R9N A;  5JA7 A;  1NPZ A;  2P86 A;  1NQC A;  4QBB A;  1Y08 A;  2R6N A;  1SNK A;  1KFX L;  1PE6 A;  3H7D A;  4N4Z A;  4YYV A;  2P0R A;  1CSB B;  1W5R A;  3B79 A;  1NL6 A;  5EF4 A;  2VFB A;  1NLJ A;  2XU5 A;  4KLB A;  3PBH A;  5CHT A;  1GCB A;  1U9V A;  1IWD A;  1TLO A;  1CV8 A;  3RVX A;  1O0E A;  1F2C A;  2BDL A;  3K24 A;  1GX3 A;  1YK7 A;  3PNR A;  2DC8 A;  3H8C A;  1MEG A;  3PW3 A;  2HHN A;  1EWP A;  1CPJ A;  4CDF B;  4YV8 A;  2ACT A;  2E02 A;  1F2B A;  1KXR A;  1KHP A;  2HH5 A;  1CJL A;  4CZW A;  4FJC A;  3WXF A;  1F2A A;  2NQD B;  2H7J A;  3HD3 A;  2VFC A;  4AXL A;  4I05 A;  1BY8 A;  3TNX A;  2R9O A;  4BQV A;  2FTD A;  6PAD A;  1PBH A;  2ATO A;  3P5U A;  3MHS A;  1BQI A;  2XU4 A;  4WA6 A;  1POP A;  1E2T A;  4AXM A;  2OUL A;  2P7U A;  5CVN B;  5CVO B;  3BPF A;  4MZS A;  1YT7 A;  1K3B B;  2JQF R;  9PAP A;  1THE A;  4Q8G A;  2GFO A;  4X6I A;  1GMY A;  3O0U A;  2B1M A;  4BPV A;  3C9E A;  2R9M A;  3KKU A;  3WXG A;  2GHU A;  3GCB A;  2BDZ A;  1DF0 A;  2HD5 A;  4QRG A;  1ICF A;  4I04 A;  4N79 A;  4PP2 E;  5CVM A;  4CDD B;  2DCA A;  2AYO A;  3P5V A;  4P6G A;  3OVZ A;  2AIM A;  2AYN A;  4CDC B;  2YJC A;  3QT4 A;  4PP1 A;  2AUX A;  4N8W A;  2NQI A;  3M99 A;  3LFY A;  1S4V A;  1ME3 A;  5K16 A;  4DMY A;  2YJB A;  3BC3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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