1KXRA

Crystal structure of calcium-bound protease core of calpain i
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
320
structure length
320
Chain Sequence
NAIKYLGQDYENLRARCLQNGVLFQDDAFPPVSHSLGFKELGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDSWLLAAIASLTLNETILHRVVPYGQSFQEGYAGIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHSAQGNEFWSALLEKAYAKVNGSYEALSGGCTSEAFEDFTGGVTEWYDLQKAPSDLYQIILKALERGSLLGCSINISDIRDLEAITFKNLVRGHAYSVTDAKQVTYQGQRVNLIRMRNPWGEVEWKGPWSDNSYEWNKVDPYEREQLRVKMEDGEFWMSFRDFIREFTKLEICN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords thiol protease DOMAINS I AND II
publication title A Ca(2+) switch aligns the active site of calpain.
pubmed doi rcsb
source organism Rattus norvegicus
molecule tags Hydrolase
total genus 96
structure length 320
sequence length 320
chains with identical sequence B
ec nomenclature ec 3.4.22.52: Calpain-1.
pdb deposition date 2002-02-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00648 Peptidase_C2 Calpain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1kxrA02
1XKGA 2R6NA 2DCDA 4P6GA 4FK5A 2G8JA 3BPFA 3H8CA 2JQGR 4MZSA 3OISA 2PNSA 9PAPA 3LFYA 2YJCA 1VJVA 1PPOA 2G8EA 1GECE 2H7JA 4XUIA 4YYSA 4FIPA 3H8BA 2VHFA 3MHHA 2CIOA 5CVNB 1CS8A 4I05A 1U9QX 2AUXA 2YJ9A 4CDCB 1F2BA 4YYRA 1NB3A 3C9EA 4N4ZA 1CJLA 3OVXA 2XU1A 2NQAA 2YJ8A 4HWYA 3WXFA 2B1MA 3CBJA 2FT2A 3IHPA 3N3KA 1NL6A 1MEGA 2JQFR 1NLJA 2AIMA 4YV8A 3TNXA 1YT7A 4AXLA 3HD3A 3CH3X 3OF9A 2XU4A 1M6DA 1ZCMA 2G6DA 1IWDA 3OF8A 1X9YA 3KWBX 3CBKA 1YALA 2AUZA 2GFOA 4DMYA 3KSEA 3PBHA 4W4UA 3BWKA 3V6CA 6PADA 3KX1A 1CSBB 1AU0A 2GHUA 1MDWA 4QH6A 2OZ2A 2FRQA 1AYWA 1CTEA 4BPVA 2FRAA 1PPNA 3USVA 4MZOA 3K8UA 1F2AA 3K24A 3QT4A 1QOLA 4I07A 3S3QA 5CVOB 2DZZA 2NQDB 1F2CA 1AU4A 1U9WA 2AYNA 1TLOA 4PI3A 2F1GA 2G7YA 3D6SA 1PADA 3N3GA 1AIMA 1HUCB 2AS8A 2DCAA 1U9VA 1MS6A 1Y08A 4AXMA 5JH3A 3P5XA 1KHPA 5CHTA 3AI8A 1EWLA 1AU2A 1BY8A 1GCBA 3RVVA 1PPDA 3OVZA 2AYOA 3KW9A 3QJ3A 4N79A 1CVZA 4K7CA 3IMAA 3E1ZB 3PW3A 5F02A 2YJ2A 1ICFA 2R9CA 3KWZA 2HH5A 2FUDA 3DF0A 2R9OA 1PPPA 1BGOA 2F7DA 3P5VA 1PBHA 2DZYA 2BDLA 1EF7A 1YK7A 3MORA 3BPMA 1ME4A 3H7DA 1MHWA 2O6XA 3IEJA 4P6EA 2Y6EA 2R9MA 4PP2E 1S4VA 3U8EA 1AYUA 2NQIA 3CH2X 2DC6A 4Q8GA 3V6EA 4CZWA 4Q8HA 1DF0A 1PE6A 1BP4A 3B79A 3N4CA 1Q6KA 1AYVA 2PADA 2DC7A 1KHQA 4OEMA 1DEUA 2E00A 2HHNA 1CV8A 2AU1A 1CQDA 4QBBA 4BS5A 1Y4HA 3RVWA 3P5UA 1O0EA 2R9FA 5EGWA 4CDDB 4DMXA 3NHEA 1EWMA 3S3RA 1ZIVA 1QXPA 1QDQA 3KFQA 1MIRA 2FQ9A 2DCCA 4W5CA 1POPA 4X6HA 2PBHA 3HHAA 4ZUXU 3IOQA 1EWOA 2Y5BA 3F75A 4YYQA 2B1NA 2FYEA 3GCBA 7PCKA 2R9NA 4XR7A 3ERVA 3KKUA 1KFXL 2IPPB 4YVAA 3O1GA 1ITOA 5CHVA 2PREA 2FTDA 1A6RA 2IBIA 3PNRA 2NQGA 1SNKA 2VHSA 1BQIA 2BDZA 2CB5A 2DJFB 4CDFB 3WXGA 3K9MA 3ZUAA 1GMYA 1TU6A 1THEA 2DC8A 1YVBA 2DJGB 3HHIA 2HXZA 4YYWA 4BS6A 4N8WA 1EWPA 2E03A 2P7UA 2OULA 1CPJA 2OP3A 1KFUL 4X6IA 3RVXA 5JA7A 1MEMA 3F5VA 2E02A 8PCHA 5K16A 4MSXA 5EF4A 3LXSA 1ATKA 2XU5A 1GLOA 1YK8A 2P0RA 2E01A 1NQCA 3I06A 1F29A 4BQVA 1U9XA 1NPZA 4OELA 2P86A 2YJBA 4CDEB 2C0YA 1PCIA 3HWNA 2ATOA 2DC9A 4I04A 1PIPA 4YYUA 5PADA 1AU3A 5A24A 1U5IA 3O0UA 3PDFA 4FJCA 4G54A 1SP4B 3MTNA 4W5BA 1ME3A 3P5WA 4YYVA 2FO5A 3QSDA 3BOWA 2ACTA 4WA6A 1NB5A 4QRVA 1AECA 4X6JA 3MHSA 4PP1A 3BC3A 4QRXA 1VSNA 3IV2A 4QRGA 1JQPA 5J94A 3IUTA 1TL9A 1CB5A 3BCNA 1STFE 1PXVA 3M99A 3H6SA 3WXEA 2DCBA 3I3TA 2ARYA 1K3BB 1FH0A 1KXRA 4PADA 2HD5A 3H89A 5CVMA 5FPWA 2XU3A 1QMYA 2WBFX 4RY2A 4BSQA 4KLBA 2AVWA
chains in the Genus database with same CATH superfamily
1XKGA 2R6NA 2DCDA 4P6GA 3ZNHA 4FK5A 2G8JA 3BPFA 3H8CA 2JQGR 4MZSA 3OISA 2PNSA 9PAPA 3LFYA 2YJCA 3PRPA 1VJVA 3TMPA 1PPOA 4RNAA 2G8EA 1GECE 2H7JA 4XUIA 4YYSA 4FIPA 3H8BA 2VHFA 3IFUA 3MHHA 2CIOA 3MJ5A 5CVNB 1CS8A 4I05A 1U9QX 2AUXA 2JTCA 2YJ9A 4CDCB 1F2BA 4YYRA 3PRMA 1NB3A 3C9EA 4R3DA 4N4ZA 1CJLA 3OVXA 2XU1A 2NQAA 2YJ8A 4HWYA 3WXFA 2B1MA 3CBJA 2FT2A 3IHPA 3N3KA 1NL6A 1MEGA 2JQFR 1NLJA 2AIMA 4YV8A 3TNXA 3MTVA 1YT7A 4AXLA 3HD3A 3CH3X 3OF9A 1DKIA 2XU4A 1M6DA 1ZCMA 2G6DA 1IWDA 3OF8A 1X9YA 3KWBX 3CBKA 1YALA 2AUZA 2GFOA 4DMYA 4IP3A 3KSEA 3PBHA 4W4UA 3BWKA 3B21A 3V6CA 6PADA 3KX1A 1CSBB 1AU0A 2GHUA 4XZXA 1MDWA 4QH6A 2OZ2A 2FRQA 1AYWA 1CTEA 5EZQA 4BPVA 3PHWA 2FRAA 1PPNA 3USVA 4MZOA 3K8UA 1F2AA 3K24A 3QT4A 1QOLA 2BTWA 4I07A 3S3QA 2DOSA 2DZZA 5CVOB 1UKFA 2NQDB 1F2CA 1AU4A 1U9WA 2AYNA 1TLOA 4PI3A 2F1GA 2G7YA 3D6SA 1PADA 3N3GA 1AIMA 1HUCB 3PHUA 4IUMA 2AS8A 2DCAA 1U9VA 1MS6A 1Y08A 4AXMA 5JH3A 3P5XA 2J7QA 1KHPA 5CHTA 3AI8A 1EWLA 3O65A 1AU2A 1BY8A 1GCBA 3RVVA 1PPDA 3OVZA 2AYOA 3KW9A 3QJ3A 4OVZA 4N79A 1CVZA 4K7CA 3IMAA 3E1ZB 3PW3A 5F02A 5JZEA 2YJ2A 1ICFA 2R9CA 3KWZA 4P16A 2HH5A 2FUDA 3DF0A 4A5UA 2R9OA 1PVJA 1PPPA 1BGOA 2F7DA 3P5VA 1PBHA 2DZYA 2Z84A 2BDLA 1EF7A 1YK7A 3MORA 3BPMA 1ME4A 3W30A 3H7DA 1MHWA 2O6XA 3IEJA 4P6EA 2Y6EA 3C0RA 2R9MA 4PP2E 1S4VA 2J7QC 3U8EA 1AYUA 2NQIA 3CH2X 4RF1A 2DC6A 4Q8GA 3V6EA 4CZWA 4Q8HA 1DF0A 1PE6A 1BP4A 4RKXA 3B79A 3N4CA 1Q6KA 1AYVA 2PADA 5EZSA 2DC7A 4D8IA 1KHQA 4OEMA 4WURA 1DEUA 2E00A 2HHNA 1CV8A 2AU1A 1CQDA 4QBBA 4BS5A 1Y4HA 5KO3A 3RVWA 3P5UA 1O0EA 3PSEA 2R9FA 3W31A 5EGWA 4CDDB 4DMXA 3NHEA 1EWMA 3S3RA 2AGAA 1ZIVA 1QXPA 1QDQA 3KFQA 3BY4A 1MIRA 2FQ9A 2DCCA 4W5CA 1POPA 4X6HA 2PBHA 3HHAA 4ZUXU 3IOQA 2BU3A 1EWOA 2Y5BA 3F75A 4YYQA 4GUAA 3BBAA 2B1NA 2FYEA 3GCBA 4BOSA 7PCKA 3E9SA 2R9NA 4XR7A 3ERVA 3KKUA 1KFXL 2IPPB 4YVAA 1YZBA 3O1GA 1ITOA 5CHVA 2PREA 2FTDA 1A6RA 2IBIA 3PNRA 2NQGA 1SNKA 2VHSA 1BQIA 4BOZA 2BDZA 2CB5A 2DJFB 4CDFB 3WXGA 4ZTBA 3K9MA 3ZUAA 4BOQA 1GMYA 1TU6A 1THEA 2BTWB 2DC8A 1YVBA 4RF0A 2DJGB 4HXDB 3HHIA 2HXZA 4YYWA 4BS6A 3MP2A 2JRIA 4N8WA 4BOPA 1EWPA 2E03A 3TRKA 2P7UA 2OULA 1CPJA 2OP3A 4OW0A 1KFUL 4X6IA 3RVXA 4M0WA 5JA7A 1MEMA 3F5VA 4D8BA 2E02A 8PCHA 5K16A 4MSXA 5EF4A 3LXSA 1ATKA 4OVZB 3BB7A 2XU5A 1GLOA 1YK8A 2P0RA 2E01A 1NQCA 3I06A 1F29A 3PHXA 4BQVA 4PT5A 1U9XA 1NPZA 4OELA 2P86A 2YJBA 4CDEB 2C0YA 1PCIA 3HWNA 4MM3B 2ATOA 2DC9A 4I04A 1PIPA 4YYUA 5PADA 1AU3A 2UZJA 3OQCA 5A24A 1U5IA 3O0UA 3PDFA 4FJCA 4G54A 1SP4B 3MTNA 4REZA 1ME3A 4W5BA 3P5WA 4YYVA 2FO5A 3QSDA 3BOWA 2ACTA 4WA6A 1NB5A 4QRVA 1AECA 4X6JA 3MHSA 3BC3A 4PP1A 4QRXA 1VSNA 3IV2A 4QRGA 3PT2A 1JQPA 3RNVA 5J94A 3IUTA 1TL9A 1CB5A 3BCNA 5E6JA 1STFE 4D8EA 1PXVA 3M99A 3H6SA 3WXEA 2FE8A 2DCBA 3I3TA 2ARYA 1K3BB 1FH0A 1KXRA 4PADA 2HD5A 3H89A 5CVMA 5FPWA 2XU3A 4BOUA 1QMYA 2WBFX 4RY2A 4BSQA 4KLBA 2AVWA 4MI7A 2HWKA
chains in the Genus database with same CATH topology
1XKGA 2R6NA 2DCDA 4P6GA 4FK5A 2G8JA 3BPFA 3H8CA 2JQGR 4MZSA 3OISA 2PNSA 9PAPA 3LFYA 2YJCA 1VJVA 1PPOA 2G8EA 1GECE 2H7JA 2VFBA 4XUIA 2VFCA 4YYSA 4FIPA 3H8BA 2VHFA 3MHHA 2CIOA 5CVNB 1CS8A 4I05A 1U9QX 2AUXA 2YJ9A 4CDCB 1F2BA 4YYRA 1NB3A 3C9EA 4N4ZA 1CJLA 3OVXA 2XU1A 2NQAA 1E2TA 2YJ8A 4HWYA 3WXFA 2B1MA 3CBJA 2FT2A 3IHPA 3N3KA 1NL6A 1MEGA 2JQFR 1NLJA 2AIMA 4YV8A 3TNXA 1YT7A 4AXLA 3HD3A 3CH3X 3OF9A 2XU4A 1M6DA 1ZCMA 2G6DA 1IWDA 3OF8A 1X9YA 3KWBX 3CBKA 1YALA 2AUZA 2GFOA 4DMYA 3KSEA 2BSZA 3PBHA 4W4UA 3BWKA 3V6CA 6PADA 3KX1A 1CSBB 1AU0A 2GHUA 1MDWA 4QH6A 2OZ2A 2FRQA 1AYWA 1CTEA 4BPVA 2FRAA 1PPNA 3USVA 4MZOA 3K8UA 1F2AA 3K24A 3QT4A 1QOLA 4I07A 3S3QA 5CVOB 2DZZA 2NQDB 1F2CA 1AU4A 1U9WA 2AYNA 1TLOA 4PI3A 2F1GA 2G7YA 3D6SA 1PADA 3N3GA 1AIMA 1HUCB 2AS8A 2DCAA 1U9VA 1MS6A 1Y08A 4AXMA 5JH3A 3P5XA 1KHPA 5CHTA 3AI8A 1EWLA 1AU2A 1BY8A 4B55A 1GCBA 3RVVA 1PPDA 3OVZA 2AYOA 3KW9A 3QJ3A 4N79A 1CVZA 4K7CA 3IMAA 3E1ZB 3PW3A 5F02A 2YJ2A 1ICFA 2R9CA 3KWZA 2HH5A 2FUDA 3DF0A 4BGFA 2R9OA 1PPPA 1BGOA 2F7DA 3P5VA 1PBHA 2DZYA 2BDLA 1EF7A 1YK7A 3MORA 3BPMA 1ME4A 3H7DA 1MHWA 2O6XA 3IEJA 4P6EA 2Y6EA 2R9MA 4PP2E 1S4VA 3U8EA 1AYUA 2NQIA 3CH2X 2DC6A 4Q8GA 3V6EA 4C5PA 4CZWA 4Q8HA 1DF0A 1PE6A 1BP4A 1GX3A 3B79A 3N4CA 1Q6KA 1AYVA 2PADA 2DC7A 1KHQA 4OEMA 1DEUA 2E00A 2HHNA 1CV8A 2AU1A 1CQDA 4QBBA 4BS5A 3D9WA 1Y4HA 3RVWA 3P5UA 1O0EA 2R9FA 5EGWA 4CDDB 4DMXA 3NHEA 1EWMA 3S3RA 1ZIVA 1QXPA 1QDQA 1W6FA 3KFQA 1MIRA 2FQ9A 2DCCA 4W5CA 1POPA 4X6HA 2PBHA 3HHAA 4ZUXU 3IOQA 1EWOA 2Y5BA 3F75A 4YYQA 2B1NA 2FYEA 3GCBA 7PCKA 2R9NA 4XR7A 3ERVA 3LTWA 3KKUA 1KFXL 2IPPB 4YVAA 3O1GA 1ITOA 5CHVA 2PREA 2FTDA 1A6RA 2IBIA 3PNRA 2NQGA 1SNKA 2VHSA 1BQIA 2BDZA 2CB5A 2DJFB 4CDFB 3WXGA 3K9MA 3ZUAA 1GMYA 1TU6A 1THEA 2DC8A 1YVBA 2DJGB 3HHIA 2HXZA 4YYWA 4BS6A 4N8WA 1W5RA 1EWPA 2E03A 2P7UA 2OULA 1CPJA 2OP3A 1KFUL 4X6IA 3RVXA 4NV8A 5JA7A 1MEMA 3F5VA 2E02A 8PCHA 5K16A 4MSXA 5EF4A 3LXSA 1ATKA 2XU5A 1GLOA 1YK8A 2P0RA 2E01A 1NQCA 3I06A 1F29A 4BQVA 1U9XA 1NPZA 4OELA 2P86A 2YJBA 4CDEB 2C0YA 1PCIA 3HWNA 2ATOA 2DC9A 4I04A 1PIPA 4YYUA 5PADA 1AU3A 5A24A 1U5IA 3O0UA 3PDFA 4FJCA 4G54A 1SP4B 3MTNA 4W5BA 1ME3A 3P5WA 4YYVA 2FO5A 3QSDA 4GUZA 3BOWA 2ACTA 4WA6A 1NB5A 4QRVA 1AECA 4X6JA 3MHSA 3BC3A 4PP1A 4QRXA 1VSNA 3IV2A 4QRGA 1JQPA 5J94A 3IUTA 1TL9A 1CB5A 3BCNA 1W4TA 1STFE 1PXVA 3M99A 3H6SA 3WXEA 4NV7A 2DCBA 3I3TA 2ARYA 1K3BB 1FH0A 1KXRA 4PADA 2HD5A 3H89A 5CVMA 5FPWA 2XU3A 1QMYA 2WBFX 4RY2A 4BSQA 4KLBA 2AVWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1XKG A;  2R6N A;  2DCD A;  4P6G A;  4FK5 A;  2G8J A;  3BPF A;  3H8C A;  2JQG R;  4MZS A;  3OIS A;  2PNS A;  9PAP A;  3LFY A;  2YJC A;  1VJV A;  1PPO A;  2G8E A;  1GEC E;  2H7J A;  4XUI A;  4YYS A;  4FIP A;  3H8B A;  2VHF A;  3MHH A;  2CIO A;  5CVN B;  1CS8 A;  4I05 A;  1U9Q X;  2AUX A;  2YJ9 A;  4CDC B;  1F2B A;  4YYR A;  1NB3 A;  3C9E A;  4N4Z A;  1CJL A;  3OVX A;  2XU1 A;  2NQA A;  2YJ8 A;  4HWY A;  3WXF A;  2B1M A;  3CBJ A;  2FT2 A;  3IHP A;  3N3K A;  1NL6 A;  1MEG A;  2JQF R;  1NLJ A;  2AIM A;  4YV8 A;  3TNX A;  1YT7 A;  4AXL A;  3HD3 A;  3CH3 X;  3OF9 A;  2XU4 A;  1M6D A;  1ZCM A;  2G6D A;  1IWD A;  3OF8 A;  1X9Y A;  3KWB X;  3CBK A;  1YAL A;  2AUZ A;  2GFO A;  4DMY A;  3KSE A;  3PBH A;  4W4U A;  3BWK A;  3V6C A;  6PAD A;  3KX1 A;  1CSB B;  1AU0 A;  2GHU A;  1MDW A;  4QH6 A;  2OZ2 A;  2FRQ A;  1AYW A;  1CTE A;  4BPV A;  2FRA A;  1PPN A;  3USV A;  4MZO A;  3K8U A;  1F2A A;  3K24 A;  3QT4 A;  1QOL A;  4I07 A;  3S3Q A;  5CVO B;  2DZZ A;  2NQD B;  1F2C A;  1AU4 A;  1U9W A;  2AYN A;  1TLO A;  4PI3 A;  2F1G A;  2G7Y A;  3D6S A;  1PAD A;  3N3G A;  1AIM A;  1HUC B;  2AS8 A;  2DCA A;  1U9V A;  1MS6 A;  1Y08 A;  4AXM A;  5JH3 A;  3P5X A;  1KHP A;  5CHT A;  3AI8 A;  1EWL A;  1AU2 A;  1BY8 A;  1GCB A;  3RVV A;  1PPD A;  3OVZ A;  2AYO A;  3KW9 A;  3QJ3 A;  4N79 A;  1CVZ A;  4K7C A;  3IMA A;  3E1Z B;  3PW3 A;  5F02 A;  2YJ2 A;  1ICF A;  2R9C A;  3KWZ A;  2HH5 A;  2FUD A;  3DF0 A;  2R9O A;  1PPP A;  1BGO A;  2F7D A;  3P5V A;  1PBH A;  2DZY A;  2BDL A;  1EF7 A;  1YK7 A;  3MOR A;  3BPM A;  1ME4 A;  3H7D A;  1MHW A;  2O6X A;  3IEJ A;  4P6E A;  2Y6E A;  2R9M A;  4PP2 E;  1S4V A;  3U8E A;  1AYU A;  2NQI A;  3CH2 X;  2DC6 A;  4Q8G A;  3V6E A;  4CZW A;  4Q8H A;  1DF0 A;  1PE6 A;  1BP4 A;  3B79 A;  3N4C A;  1Q6K A;  1AYV A;  2PAD A;  2DC7 A;  1KHQ A;  4OEM A;  1DEU A;  2E00 A;  2HHN A;  1CV8 A;  2AU1 A;  1CQD A;  4QBB A;  4BS5 A;  1Y4H A;  3RVW A;  3P5U A;  1O0E A;  2R9F A;  5EGW A;  4CDD B;  4DMX A;  3NHE A;  1EWM A;  3S3R A;  1ZIV A;  1QXP A;  1QDQ A;  3KFQ A;  1MIR A;  2FQ9 A;  2DCC A;  4W5C A;  1POP A;  4X6H A;  2PBH A;  3HHA A;  4ZUX U;  3IOQ A;  1EWO A;  2Y5B A;  3F75 A;  4YYQ A;  2B1N A;  2FYE A;  3GCB A;  7PCK A;  2R9N A;  4XR7 A;  3ERV A;  3KKU A;  1KFX L;  2IPP B;  4YVA A;  3O1G A;  1ITO A;  5CHV A;  2PRE A;  2FTD A;  1A6R A;  2IBI A;  3PNR A;  2NQG A;  1SNK A;  2VHS A;  1BQI A;  2BDZ A;  2CB5 A;  2DJF B;  4CDF B;  3WXG A;  3K9M A;  3ZUA A;  1GMY A;  1TU6 A;  1THE A;  2DC8 A;  1YVB A;  2DJG B;  3HHI A;  2HXZ A;  4YYW A;  4BS6 A;  4N8W A;  1EWP A;  2E03 A;  2P7U A;  2OUL A;  1CPJ A;  2OP3 A;  1KFU L;  4X6I A;  3RVX A;  5JA7 A;  1MEM A;  3F5V A;  2E02 A;  8PCH A;  5K16 A;  4MSX A;  5EF4 A;  3LXS A;  1ATK A;  2XU5 A;  1GLO A;  1YK8 A;  2P0R A;  2E01 A;  1NQC A;  3I06 A;  1F29 A;  4BQV A;  1U9X A;  1NPZ A;  4OEL A;  2P86 A;  2YJB A;  4CDE B;  2C0Y A;  1PCI A;  3HWN A;  2ATO A;  2DC9 A;  4I04 A;  1PIP A;  4YYU A;  5PAD A;  1AU3 A;  5A24 A;  1U5I A;  3O0U A;  3PDF A;  4FJC A;  4G54 A;  1SP4 B;  3MTN A;  4W5B A;  1ME3 A;  3P5W A;  4YYV A;  2FO5 A;  3QSD A;  3BOW A;  2ACT A;  4WA6 A;  1NB5 A;  4QRV A;  1AEC A;  4X6J A;  3MHS A;  4PP1 A;  3BC3 A;  4QRX A;  1VSN A;  3IV2 A;  4QRG A;  1JQP A;  5J94 A;  3IUT A;  1TL9 A;  1CB5 A;  3BCN A;  1STF E;  1PXV A;  3M99 A;  3H6S A;  3WXE A;  2DCB A;  3I3T A;  2ARY A;  1K3B B;  1FH0 A;  1KXR A;  4PAD A;  2HD5 A;  3H89 A;  5CVM A;  5FPW A;  2XU3 A;  1QMY A;  2WBF X;  4RY2 A;  4BSQ A;  4KLB A;  2AVW A; 
#chains in the Genus database with same CATH topology
 1XKG A;  2R6N A;  2DCD A;  4P6G A;  3ZNH A;  4FK5 A;  2G8J A;  3BPF A;  3H8C A;  2JQG R;  4MZS A;  3OIS A;  2PNS A;  9PAP A;  3LFY A;  2YJC A;  3PRP A;  1VJV A;  3TMP A;  1PPO A;  4RNA A;  2G8E A;  1GEC E;  2H7J A;  4XUI A;  4YYS A;  4FIP A;  3H8B A;  2VHF A;  3IFU A;  3MHH A;  2CIO A;  3MJ5 A;  5CVN B;  1CS8 A;  4I05 A;  1U9Q X;  2AUX A;  2JTC A;  2YJ9 A;  4CDC B;  1F2B A;  4YYR A;  3PRM A;  1NB3 A;  3C9E A;  4R3D A;  4N4Z A;  1CJL A;  3OVX A;  2XU1 A;  2NQA A;  2YJ8 A;  4HWY A;  3WXF A;  2B1M A;  3CBJ A;  2FT2 A;  3IHP A;  3N3K A;  1NL6 A;  1MEG A;  2JQF R;  1NLJ A;  2AIM A;  4YV8 A;  3TNX A;  3MTV A;  1YT7 A;  4AXL A;  3HD3 A;  3CH3 X;  3OF9 A;  1DKI A;  2XU4 A;  1M6D A;  1ZCM A;  2G6D A;  1IWD A;  3OF8 A;  1X9Y A;  3KWB X;  3CBK A;  1YAL A;  2AUZ A;  2GFO A;  4DMY A;  4IP3 A;  3KSE A;  3PBH A;  4W4U A;  3BWK A;  3B21 A;  3V6C A;  6PAD A;  3KX1 A;  1CSB B;  1AU0 A;  2GHU A;  4XZX A;  1MDW A;  4QH6 A;  2OZ2 A;  2FRQ A;  1AYW A;  1CTE A;  5EZQ A;  4BPV A;  3PHW A;  2FRA A;  1PPN A;  3USV A;  4MZO A;  3K8U A;  1F2A A;  3K24 A;  3QT4 A;  1QOL A;  2BTW A;  4I07 A;  3S3Q A;  2DOS A;  2DZZ A;  5CVO B;  1UKF A;  2NQD B;  1F2C A;  1AU4 A;  1U9W A;  2AYN A;  1TLO A;  4PI3 A;  2F1G A;  2G7Y A;  3D6S A;  1PAD A;  3N3G A;  1AIM A;  1HUC B;  3PHU A;  4IUM A;  2AS8 A;  2DCA A;  1U9V A;  1MS6 A;  1Y08 A;  4AXM A;  5JH3 A;  3P5X A;  2J7Q A;  1KHP A;  5CHT A;  3AI8 A;  1EWL A;  3O65 A;  1AU2 A;  1BY8 A;  1GCB A;  3RVV A;  1PPD A;  3OVZ A;  2AYO A;  3KW9 A;  3QJ3 A;  4OVZ A;  4N79 A;  1CVZ A;  4K7C A;  3IMA A;  3E1Z B;  3PW3 A;  5F02 A;  5JZE A;  2YJ2 A;  1ICF A;  2R9C A;  3KWZ A;  4P16 A;  2HH5 A;  2FUD A;  3DF0 A;  4A5U A;  2R9O A;  1PVJ A;  1PPP A;  1BGO A;  2F7D A;  3P5V A;  1PBH A;  2DZY A;  2Z84 A;  2BDL A;  1EF7 A;  1YK7 A;  3MOR A;  3BPM A;  1ME4 A;  3W30 A;  3H7D A;  1MHW A;  2O6X A;  3IEJ A;  4P6E A;  2Y6E A;  3C0R A;  2R9M A;  4PP2 E;  1S4V A;  2J7Q C;  3U8E A;  1AYU A;  2NQI A;  3CH2 X;  4RF1 A;  2DC6 A;  4Q8G A;  3V6E A;  4CZW A;  4Q8H A;  1DF0 A;  1PE6 A;  1BP4 A;  4RKX A;  3B79 A;  3N4C A;  1Q6K A;  1AYV A;  2PAD A;  5EZS A;  2DC7 A;  4D8I A;  1KHQ A;  4OEM A;  4WUR A;  1DEU A;  2E00 A;  2HHN A;  1CV8 A;  2AU1 A;  1CQD A;  4QBB A;  4BS5 A;  1Y4H A;  5KO3 A;  3RVW A;  3P5U A;  1O0E A;  3PSE A;  2R9F A;  3W31 A;  5EGW A;  4CDD B;  4DMX A;  3NHE A;  1EWM A;  3S3R A;  2AGA A;  1ZIV A;  1QXP A;  1QDQ A;  3KFQ A;  3BY4 A;  1MIR A;  2FQ9 A;  2DCC A;  4W5C A;  1POP A;  4X6H A;  2PBH A;  3HHA A;  4ZUX U;  3IOQ A;  2BU3 A;  1EWO A;  2Y5B A;  3F75 A;  4YYQ A;  4GUA A;  3BBA A;  2B1N A;  2FYE A;  3GCB A;  4BOS A;  7PCK A;  3E9S A;  2R9N A;  4XR7 A;  3ERV A;  3KKU A;  1KFX L;  2IPP B;  4YVA A;  1YZB A;  3O1G A;  1ITO A;  5CHV A;  2PRE A;  2FTD A;  1A6R A;  2IBI A;  3PNR A;  2NQG A;  1SNK A;  2VHS A;  1BQI A;  4BOZ A;  2BDZ A;  2CB5 A;  2DJF B;  4CDF B;  3WXG A;  4ZTB A;  3K9M A;  3ZUA A;  4BOQ A;  1GMY A;  1TU6 A;  1THE A;  2BTW B;  2DC8 A;  1YVB A;  4RF0 A;  2DJG B;  4HXD B;  3HHI A;  2HXZ A;  4YYW A;  4BS6 A;  3MP2 A;  2JRI A;  4N8W A;  4BOP A;  1EWP A;  2E03 A;  3TRK A;  2P7U A;  2OUL A;  1CPJ A;  2OP3 A;  4OW0 A;  1KFU L;  4X6I A;  3RVX A;  4M0W A;  5JA7 A;  1MEM A;  3F5V A;  4D8B A;  2E02 A;  8PCH A;  5K16 A;  4MSX A;  5EF4 A;  3LXS A;  1ATK A;  4OVZ B;  3BB7 A;  2XU5 A;  1GLO A;  1YK8 A;  2P0R A;  2E01 A;  1NQC A;  3I06 A;  1F29 A;  3PHX A;  4BQV A;  4PT5 A;  1U9X A;  1NPZ A;  4OEL A;  2P86 A;  2YJB A;  4CDE B;  2C0Y A;  1PCI A;  3HWN A;  4MM3 B;  2ATO A;  2DC9 A;  4I04 A;  1PIP A;  4YYU A;  5PAD A;  1AU3 A;  2UZJ A;  3OQC A;  5A24 A;  1U5I A;  3O0U A;  3PDF A;  4FJC A;  4G54 A;  1SP4 B;  3MTN A;  4REZ A;  1ME3 A;  4W5B A;  3P5W A;  4YYV A;  2FO5 A;  3QSD A;  3BOW A;  2ACT A;  4WA6 A;  1NB5 A;  4QRV A;  1AEC A;  4X6J A;  3MHS A;  3BC3 A;  4PP1 A;  4QRX A;  1VSN A;  3IV2 A;  4QRG A;  3PT2 A;  1JQP A;  3RNV A;  5J94 A;  3IUT A;  1TL9 A;  1CB5 A;  3BCN A;  5E6J A;  1STF E;  4D8E A;  1PXV A;  3M99 A;  3H6S A;  3WXE A;  2FE8 A;  2DCB A;  3I3T A;  2ARY A;  1K3B B;  1FH0 A;  1KXR A;  4PAD A;  2HD5 A;  3H89 A;  5CVM A;  5FPW A;  2XU3 A;  4BOU A;  1QMY A;  2WBF X;  4RY2 A;  4BSQ A;  4KLB A;  2AVW A;  4MI7 A;  2HWK A; 
#chains in the Genus database with same CATH homology
 1XKG A;  2R6N A;  2DCD A;  4P6G A;  4FK5 A;  2G8J A;  3BPF A;  3H8C A;  2JQG R;  4MZS A;  3OIS A;  2PNS A;  9PAP A;  3LFY A;  2YJC A;  1VJV A;  1PPO A;  2G8E A;  1GEC E;  2H7J A;  2VFB A;  4XUI A;  2VFC A;  4YYS A;  4FIP A;  3H8B A;  2VHF A;  3MHH A;  2CIO A;  5CVN B;  1CS8 A;  4I05 A;  1U9Q X;  2AUX A;  2YJ9 A;  4CDC B;  1F2B A;  4YYR A;  1NB3 A;  3C9E A;  4N4Z A;  1CJL A;  3OVX A;  2XU1 A;  2NQA A;  1E2T A;  2YJ8 A;  4HWY A;  3WXF A;  2B1M A;  3CBJ A;  2FT2 A;  3IHP A;  3N3K A;  1NL6 A;  1MEG A;  2JQF R;  1NLJ A;  2AIM A;  4YV8 A;  3TNX A;  1YT7 A;  4AXL A;  3HD3 A;  3CH3 X;  3OF9 A;  2XU4 A;  1M6D A;  1ZCM A;  2G6D A;  1IWD A;  3OF8 A;  1X9Y A;  3KWB X;  3CBK A;  1YAL A;  2AUZ A;  2GFO A;  4DMY A;  3KSE A;  2BSZ A;  3PBH A;  4W4U A;  3BWK A;  3V6C A;  6PAD A;  3KX1 A;  1CSB B;  1AU0 A;  2GHU A;  1MDW A;  4QH6 A;  2OZ2 A;  2FRQ A;  1AYW A;  1CTE A;  4BPV A;  2FRA A;  1PPN A;  3USV A;  4MZO A;  3K8U A;  1F2A A;  3K24 A;  3QT4 A;  1QOL A;  4I07 A;  3S3Q A;  5CVO B;  2DZZ A;  2NQD B;  1F2C A;  1AU4 A;  1U9W A;  2AYN A;  1TLO A;  4PI3 A;  2F1G A;  2G7Y A;  3D6S A;  1PAD A;  3N3G A;  1AIM A;  1HUC B;  2AS8 A;  2DCA A;  1U9V A;  1MS6 A;  1Y08 A;  4AXM A;  5JH3 A;  3P5X A;  1KHP A;  5CHT A;  3AI8 A;  1EWL A;  1AU2 A;  1BY8 A;  4B55 A;  1GCB A;  3RVV A;  1PPD A;  3OVZ A;  2AYO A;  3KW9 A;  3QJ3 A;  4N79 A;  1CVZ A;  4K7C A;  3IMA A;  3E1Z B;  3PW3 A;  5F02 A;  2YJ2 A;  1ICF A;  2R9C A;  3KWZ A;  2HH5 A;  2FUD A;  3DF0 A;  4BGF A;  2R9O A;  1PPP A;  1BGO A;  2F7D A;  3P5V A;  1PBH A;  2DZY A;  2BDL A;  1EF7 A;  1YK7 A;  3MOR A;  3BPM A;  1ME4 A;  3H7D A;  1MHW A;  2O6X A;  3IEJ A;  4P6E A;  2Y6E A;  2R9M A;  4PP2 E;  1S4V A;  3U8E A;  1AYU A;  2NQI A;  3CH2 X;  2DC6 A;  4Q8G A;  3V6E A;  4C5P A;  4CZW A;  4Q8H A;  1DF0 A;  1PE6 A;  1BP4 A;  1GX3 A;  3B79 A;  3N4C A;  1Q6K A;  1AYV A;  2PAD A;  2DC7 A;  1KHQ A;  4OEM A;  1DEU A;  2E00 A;  2HHN A;  1CV8 A;  2AU1 A;  1CQD A;  4QBB A;  4BS5 A;  3D9W A;  1Y4H A;  3RVW A;  3P5U A;  1O0E A;  2R9F A;  5EGW A;  4CDD B;  4DMX A;  3NHE A;  1EWM A;  3S3R A;  1ZIV A;  1QXP A;  1QDQ A;  1W6F A;  3KFQ A;  1MIR A;  2FQ9 A;  2DCC A;  4W5C A;  1POP A;  4X6H A;  2PBH A;  3HHA A;  4ZUX U;  3IOQ A;  1EWO A;  2Y5B A;  3F75 A;  4YYQ A;  2B1N A;  2FYE A;  3GCB A;  7PCK A;  2R9N A;  4XR7 A;  3ERV A;  3LTW A;  3KKU A;  1KFX L;  2IPP B;  4YVA A;  3O1G A;  1ITO A;  5CHV A;  2PRE A;  2FTD A;  1A6R A;  2IBI A;  3PNR A;  2NQG A;  1SNK A;  2VHS A;  1BQI A;  2BDZ A;  2CB5 A;  2DJF B;  4CDF B;  3WXG A;  3K9M A;  3ZUA A;  1GMY A;  1TU6 A;  1THE A;  2DC8 A;  1YVB A;  2DJG B;  3HHI A;  2HXZ A;  4YYW A;  4BS6 A;  4N8W A;  1W5R A;  1EWP A;  2E03 A;  2P7U A;  2OUL A;  1CPJ A;  2OP3 A;  1KFU L;  4X6I A;  3RVX A;  4NV8 A;  5JA7 A;  1MEM A;  3F5V A;  2E02 A;  8PCH A;  5K16 A;  4MSX A;  5EF4 A;  3LXS A;  1ATK A;  2XU5 A;  1GLO A;  1YK8 A;  2P0R A;  2E01 A;  1NQC A;  3I06 A;  1F29 A;  4BQV A;  1U9X A;  1NPZ A;  4OEL A;  2P86 A;  2YJB A;  4CDE B;  2C0Y A;  1PCI A;  3HWN A;  2ATO A;  2DC9 A;  4I04 A;  1PIP A;  4YYU A;  5PAD A;  1AU3 A;  5A24 A;  1U5I A;  3O0U A;  3PDF A;  4FJC A;  4G54 A;  1SP4 B;  3MTN A;  4W5B A;  1ME3 A;  3P5W A;  4YYV A;  2FO5 A;  3QSD A;  4GUZ A;  3BOW A;  2ACT A;  4WA6 A;  1NB5 A;  4QRV A;  1AEC A;  4X6J A;  3MHS A;  3BC3 A;  4PP1 A;  4QRX A;  1VSN A;  3IV2 A;  4QRG A;  1JQP A;  5J94 A;  3IUT A;  1TL9 A;  1CB5 A;  3BCN A;  1W4T A;  1STF E;  1PXV A;  3M99 A;  3H6S A;  3WXE A;  4NV7 A;  2DCB A;  3I3T A;  2ARY A;  1K3B B;  1FH0 A;  1KXR A;  4PAD A;  2HD5 A;  3H89 A;  5CVM A;  5FPW A;  2XU3 A;  1QMY A;  2WBF X;  4RY2 A;  4BSQ A;  4KLB A;  2AVW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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