1KXRA

Crystal structure of calcium-bound protease core of calpain i
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
320
structure length
320
Chain Sequence
NAIKYLGQDYENLRARCLQNGVLFQDDAFPPVSHSLGFKELGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDSWLLAAIASLTLNETILHRVVPYGQSFQEGYAGIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHSAQGNEFWSALLEKAYAKVNGSYEALSGGCTSEAFEDFTGGVTEWYDLQKAPSDLYQIILKALERGSLLGCSINISDIRDLEAITFKNLVRGHAYSVTDAKQVTYQGQRVNLIRMRNPWGEVEWKGPWSDNSYEWNKVDPYEREQLRVKMEDGEFWMSFRDFIREFTKLEICN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Ca(2+) switch aligns the active site of calpain.
pubmed doi rcsb
molecule keywords thiol protease DOMAINS I AND II
molecule tags Hydrolase
source organism Rattus norvegicus
total genus 96
structure length 320
sequence length 320
chains with identical sequence B
ec nomenclature ec 3.4.22.52: Calpain-1.
pdb deposition date 2002-02-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00648 Peptidase_C2 Calpain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1kxrA02
3H7DA 3PDFA 1CS8A 1Q6KA 4N8WA 1M6DA 1KFXL 2CB5A 3BOWA 3PW3A 3P5XA 3KKUA 1U9XA 2OP3A 1AU0A 3H6SA 1ICFA 4MSXA 1MS6A 2F7DA 2G6DA 1BP4A 2WBFX 4PP1A 4OELA 4P6GA 3OVXA 3IUTA 2R9CA 2NQIA 3HHIA 4QRXA 3D6SA 4N79A 1F2AA 4W5BA 4AXLA 2ATOA 4YV8A 2DCCA 3I3TA 4CDEB 1NLJA 2DC8A 3O1GA 2FQ9A 2AVWA 4Q8GA 1STFE 1SNKA 4FJCA 1EWMA 2ARYA 3N4CA 2R9FA 1GCBA 3HWNA 1BQIA 3CH3X 1YVBA 2DZZA 2YJ9A 6PADA 2B1NA 5F02A 1KHQA 3F75A 3RVVA 4MZOA 3V6CA 2GFOA 3F5VA 3KWBX 2HD5A 4AXMA 1PIPA 1NB5A 1CPJA 2Y5BA 3N3KA 4YYRA 3IHPA 1KHPA 4X6JA 1QOLA 1EWPA 3CH2X 2E00A 1ITOA 3RVWA 2AU1A 2DC9A 4PP2E 1NB3A 4N4ZA 3OVZA 7PCKA 2FT2A 3LFYA 1TL9A 3I06A 5FPWA 2JQGR 1TU6A 1AECA 4YYUA 1K3BB 1CVZA 5A24A 9PAPA 3IOQA 4I04A 4KLBA 1KXRA 4CDDB 2G8EA 2PADA 2FRQA 2C0YA 4BQVA 3HD3A 3BWKA 1TLOA 2VHFA 1QMYA 3B79A 4DMYA 1MHWA 1PCIA 4PADA 1CSBB 2DJGB 3H8BA 3OISA 3AI8A 2YJ8A 3S3RA 2GHUA 1BY8A 2H7JA 1IWDA 5JA7A 1VJVA 2R9NA 2AYOA 1F2BA 1KFUL 1PPDA 4QRVA 1YK8A 3BC3A 1GLOA 2BDLA 1NPZA 4ZUXU 2B1MA 1U9WA 1CQDA 1FH0A 3C9EA 1PBHA 2XU4A 1XKGA 1ME3A 2E01A 2HH5A 1F29A 2NQDB 1F2CA 1ATKA 1CV8A 2DJFB 2CIOA 2FUDA 3CBJA 3OF8A 1CB5A 1THEA 2FRAA 1EWLA 2R9OA 5PADA 1O0EA 4YYQA 4BPVA 3H89A 2R6NA 3WXGA 3MHSA 2DCBA 2PBHA 4QH6A 1DEUA 1VSNA 3P5VA 4YYWA 2P7UA 3GCBA 2FO5A 3IMAA 1MDWA 4BS5A 4WA6A 1NL6A 1CTEA 5CVNB 2O6XA 3P5WA 1AYVA 3K24A 1AIMA 1YT7A 2E02A 1NQCA 3P5UA 1ME4A 1QXPA 4RY2A 1X9YA 1POPA 3MTNA 2R9MA 3IV2A 1AYUA 1Y4HA 1U5IA 1EF7A 4YYSA 3BCNA 1PPPA 1U9QX 1JQPA 2NQAA 5EGWA 4CDFB 4X6IA 3BPMA 1YK7A 5J94A 4CDCB 1AYWA 2P0RA 2DCDA 2AUZA 2YJ2A 2PNSA 2HXZA 2DZYA 1ZCMA 5JH3A 2DC7A 3H8CA 4I07A 2PREA 2JQFR 1PADA 4QBBA 4MZSA 5K16A 3USVA 5CHVA 1MEMA 3CBKA 3BPFA 1PPNA 2AS8A 2BDZA 2DC6A 2FYEA 4QRGA 2F1GA 4OEMA 2G8JA 1GECE 1S4VA 3DF0A 5CVOB 3OF9A 1SP4B 3RVXA 2YJCA 2AUXA 4K7CA 8PCHA 3E1ZB 4P6EA 3HHAA 3PNRA 4FIPA 1U9VA 1PXVA 2AIMA 2IPPB 2IBIA 3S3QA 1CJLA 2XU1A 3O0UA 2VHSA 1PE6A 1A6RA 1QDQA 1DF0A 5EF4A 1AU2A 2E03A 3KW9A 1AU4A 3U8EA 3WXFA 1GMYA 1ZIVA 3QJ3A 3ERVA 2OULA 1BGOA 3V6EA 2OZ2A 4W4UA 2AYNA 1HUCB 1Y08A 1EWOA 4BS6A 2YJBA 2G7YA 3K9MA 3KX1A 1AU3A 3QT4A 3KSEA 4DMXA 2Y6EA 4HWYA 3WXEA 2HHNA 4G54A 4Q8HA 2NQGA 3M99A 3KWZA 3KFQA 2FTDA 5CVMA 3TNXA 4XUIA 4X6HA 3QSDA 2P86A 3LXSA 1MIRA 4BSQA 4CZWA 2ACTA 3ZUAA 2XU3A 3PBHA 4FK5A 4YVAA 3IEJA 4XR7A 3K8UA 1MEGA 4YYVA 4PI3A 3NHEA 2DCAA 2XU5A 4I05A 3N3GA 5CHTA 3MORA 4W5CA 1YALA 1PPOA 3MHHA
chains in the Genus database with same CATH superfamily
3H7DA 3PDFA 1CS8A 1Q6KA 4N8WA 1M6DA 3TRKA 1KFXL 2CB5A 4OVZA 3BOWA 4PT5A 3PW3A 3P5XA 3KKUA 1U9XA 2OP3A 3PHUA 1AU0A 3H6SA 1ICFA 4MSXA 1MS6A 4GUAA 2F7DA 3BB7A 2G6DA 1BP4A 2WBFX 4PP1A 4OELA 4P6GA 3OVXA 3IUTA 5JZEA 3ZNHA 2R9CA 2NQIA 4RKXA 3HHIA 3OQCA 2AGAA 4QRXA 3D6SA 4N79A 1F2AA 4W5BA 4AXLA 2ATOA 4YV8A 2DCCA 3I3TA 4CDEB 1NLJA 2DC8A 3O1GA 2FQ9A 2AVWA 4Q8GA 4OVZB 1STFE 1SNKA 4FJCA 1EWMA 2ARYA 3N4CA 2R9FA 1GCBA 2Z84A 3HWNA 1BQIA 3CH3X 2JTCA 1YVBA 2DZZA 2YJ9A 6PADA 2B1NA 5F02A 1KHQA 3F75A 3RVVA 4MZOA 3V6CA 2BU3A 2GFOA 3F5VA 3KWBX 2HD5A 4RF1A 4AXMA 1PIPA 1NB5A 1CPJA 2Y5BA 3N3KA 4YYRA 3IHPA 1KHPA 4X6JA 1QOLA 2DOSA 3PRMA 1EWPA 4R3DA 3O65A 3CH2X 2E00A 4MM3B 3PSEA 3E9SA 1ITOA 3RVWA 2AU1A 2FE8A 2DC9A 4PP2E 1NB3A 4N4ZA 3OVZA 7PCKA 2FT2A 3LFYA 1TL9A 3I06A 5FPWA 2JQGR 1TU6A 1AECA 3MJ5A 4YYUA 1K3BB 1CVZA 4D8IA 5A24A 9PAPA 4MI7A 3IOQA 4I04A 4KLBA 1KXRA 4CDDB 2G8EA 2PADA 2FRQA 2C0YA 4BQVA 3HD3A 3BWKA 1TLOA 2VHFA 1QMYA 3B79A 3PRPA 4DMYA 1MHWA 1PCIA 4HXDB 4PADA 1CSBB 2DJGB 3H8BA 3OISA 3AI8A 2YJ8A 3S3RA 2GHUA 1BY8A 2H7JA 1IWDA 4BOSA 3B21A 5JA7A 1VJVA 2R9NA 2AYOA 1F2BA 5EZQA 1KFUL 1PPDA 4QRVA 1YK8A 3BC3A 3W31A 1GLOA 2BDLA 1NPZA 4ZUXU 2B1MA 1U9WA 1CQDA 1FH0A 3C9EA 1PBHA 2XU4A 1XKGA 1ME3A 2E01A 2HH5A 1F29A 3MP2A 5E6JA 1YZBA 2NQDB 1F2CA 1ATKA 1CV8A 2DJFB 2CIOA 2FUDA 3CBJA 3OF8A 1CB5A 1THEA 2BTWA 2FRAA 1EWLA 2R9OA 4REZA 5PADA 2UZJA 1O0EA 4YYQA 4BPVA 3H89A 2R6NA 3WXGA 2J7QC 3MHSA 2DCBA 2PBHA 4QH6A 1DEUA 2J7QA 1VSNA 3P5VA 4YYWA 3RNVA 2P7UA 3GCBA 3PT2A 2FO5A 4XZXA 3IMAA 1MDWA 4BS5A 4WA6A 1NL6A 1CTEA 5CVNB 2O6XA 2JRIA 3P5WA 1AYVA 2BTWB 3K24A 5EZSA 1AIMA 1YT7A 2E02A 1NQCA 3P5UA 1ME4A 1QXPA 4RY2A 4BOQA 1X9YA 1POPA 3MTNA 2R9MA 3IV2A 1AYUA 3MTVA 1Y4HA 1U5IA 1EF7A 4YYSA 3BCNA 1PPPA 1U9QX 3C0RA 1JQPA 3PHXA 2NQAA 4IUMA 5EGWA 4CDFB 4X6IA 3BPMA 1YK7A 3IFUA 5J94A 4CDCB 1AYWA 2P0RA 2DCDA 2AUZA 2YJ2A 2PNSA 2HXZA 4BOPA 1DKIA 2DZYA 1ZCMA 5JH3A 2DC7A 3H8CA 4I07A 2PREA 2JQFR 1PADA 4QBBA 4MZSA 5K16A 4WURA 3USVA 5CHVA 1MEMA 3CBKA 3BPFA 1PPNA 2AS8A 2BDZA 3PHWA 4RF0A 2DC6A 3BY4A 2FYEA 4QRGA 2F1GA 4OEMA 2G8JA 4P16A 1GECE 1S4VA 3DF0A 5CVOB 3OF9A 1SP4B 3RVXA 2YJCA 2AUXA 4K7CA 8PCHA 3E1ZB 4P6EA 3HHAA 3PNRA 4FIPA 4RNAA 4D8BA 1U9VA 1PXVA 2AIMA 2IPPB 2IBIA 3S3QA 1CJLA 2XU1A 3O0UA 4A5UA 2VHSA 1PE6A 1A6RA 1QDQA 1DF0A 5EF4A 1AU2A 2E03A 3KW9A 1AU4A 3U8EA 3WXFA 1GMYA 1ZIVA 3QJ3A 3ERVA 3TMPA 2OULA 1BGOA 3V6EA 2OZ2A 4W4UA 2AYNA 1HUCB 1Y08A 1EWOA 4BS6A 2YJBA 4IP3A 2G7YA 3K9MA 3KX1A 1AU3A 3QT4A 3KSEA 4DMXA 1UKFA 2Y6EA 4HWYA 3WXEA 2HHNA 3BBAA 3W30A 4BOUA 4G54A 4Q8HA 4M0WA 2NQGA 3M99A 3KWZA 3KFQA 2FTDA 5CVMA 3TNXA 4XUIA 4ZTBA 2HWKA 4X6HA 3QSDA 4BOZA 2P86A 3LXSA 1MIRA 4BSQA 4CZWA 2ACTA 3ZUAA 4D8EA 2XU3A 3PBHA 4FK5A 4YVAA 5KO3A 3IEJA 4XR7A 3K8UA 1MEGA 4YYVA 4PI3A 3NHEA 2DCAA 1PVJA 2XU5A 4I05A 3N3GA 5CHTA 3MORA 4OW0A 4W5CA 1YALA 1PPOA 3MHHA
chains in the Genus database with same CATH topology
3H7DA 3PDFA 1CS8A 1Q6KA 4N8WA 1M6DA 1KFXL 2CB5A 3BOWA 3PW3A 3P5XA 3KKUA 1U9XA 2OP3A 1AU0A 3H6SA 1ICFA 4MSXA 1MS6A 2F7DA 2G6DA 1BP4A 2WBFX 4PP1A 4OELA 4P6GA 3OVXA 3IUTA 2R9CA 2NQIA 1E2TA 3HHIA 4QRXA 3D6SA 4N79A 1F2AA 4W5BA 4AXLA 2ATOA 4YV8A 2DCCA 3I3TA 4CDEB 1NLJA 2DC8A 3O1GA 2FQ9A 2AVWA 4Q8GA 1STFE 1SNKA 4FJCA 1EWMA 2ARYA 3N4CA 2R9FA 1GCBA 3HWNA 1BQIA 3CH3X 1YVBA 2DZZA 2YJ9A 6PADA 2B1NA 5F02A 1KHQA 3F75A 3RVVA 4MZOA 3V6CA 2GFOA 3F5VA 3KWBX 2HD5A 4AXMA 1PIPA 1NB5A 1CPJA 2Y5BA 3N3KA 4YYRA 3IHPA 1KHPA 4X6JA 1QOLA 1EWPA 1W4TA 3CH2X 1GX3A 2E00A 1ITOA 3RVWA 2AU1A 4NV8A 2DC9A 3LTWA 4PP2E 1NB3A 4N4ZA 3OVZA 7PCKA 2FT2A 3LFYA 1TL9A 3I06A 5FPWA 2JQGR 1TU6A 1AECA 4YYUA 1K3BB 1CVZA 5A24A 9PAPA 3IOQA 4I04A 4KLBA 1KXRA 4CDDB 2G8EA 2PADA 2FRQA 2C0YA 4BQVA 3HD3A 3BWKA 1TLOA 2VHFA 4GUZA 1QMYA 3B79A 4DMYA 1MHWA 1PCIA 4PADA 1CSBB 2DJGB 3H8BA 3OISA 3AI8A 2YJ8A 3S3RA 2GHUA 1BY8A 2H7JA 1IWDA 5JA7A 1VJVA 2R9NA 2AYOA 1F2BA 1KFUL 1PPDA 4QRVA 1YK8A 3BC3A 1GLOA 2BDLA 1NPZA 4ZUXU 2B1MA 1U9WA 1CQDA 1FH0A 3C9EA 1PBHA 2XU4A 1XKGA 1ME3A 2E01A 2HH5A 1F29A 2NQDB 1F2CA 4NV7A 1ATKA 1CV8A 2DJFB 2CIOA 2FUDA 3CBJA 3OF8A 1CB5A 1THEA 2FRAA 1EWLA 2R9OA 5PADA 1O0EA 4YYQA 4BPVA 3H89A 2R6NA 3WXGA 3MHSA 2DCBA 2PBHA 4QH6A 1DEUA 1VSNA 3P5VA 4YYWA 2P7UA 3GCBA 2FO5A 3IMAA 1MDWA 4BS5A 4WA6A 1NL6A 1CTEA 5CVNB 2O6XA 3P5WA 1AYVA 3K24A 1AIMA 1YT7A 2E02A 1NQCA 3P5UA 1ME4A 1QXPA 4RY2A 4BGFA 1X9YA 1POPA 3MTNA 2R9MA 3IV2A 1AYUA 1Y4HA 1U5IA 1EF7A 4YYSA 3BCNA 1PPPA 1U9QX 1JQPA 2NQAA 5EGWA 4CDFB 4X6IA 3BPMA 1YK7A 5J94A 4CDCB 1AYWA 2P0RA 2DCDA 2AUZA 2YJ2A 2PNSA 2HXZA 2DZYA 1ZCMA 5JH3A 2DC7A 3H8CA 4I07A 2PREA 2JQFR 1PADA 4QBBA 4MZSA 5K16A 3USVA 5CHVA 1MEMA 3CBKA 3BPFA 1PPNA 2AS8A 2BDZA 2BSZA 2DC6A 2FYEA 4QRGA 2F1GA 4OEMA 4B55A 2G8JA 1GECE 1S4VA 3DF0A 5CVOB 3OF9A 1SP4B 3RVXA 2YJCA 2AUXA 4K7CA 8PCHA 3E1ZB 4P6EA 3HHAA 3PNRA 4FIPA 1U9VA 1PXVA 2AIMA 2IPPB 2IBIA 3S3QA 1CJLA 2XU1A 3O0UA 2VHSA 1PE6A 1A6RA 1QDQA 1DF0A 3D9WA 5EF4A 1AU2A 2E03A 3KW9A 1AU4A 1W6FA 3U8EA 3WXFA 1GMYA 1ZIVA 3QJ3A 3ERVA 2OULA 1BGOA 3V6EA 4C5PA 2OZ2A 4W4UA 2AYNA 1W5RA 1HUCB 1Y08A 1EWOA 4BS6A 2YJBA 2G7YA 3K9MA 3KX1A 1AU3A 3QT4A 3KSEA 4DMXA 2VFBA 2VFCA 2Y6EA 4HWYA 3WXEA 2HHNA 4G54A 4Q8HA 2NQGA 3M99A 3KWZA 3KFQA 2FTDA 5CVMA 3TNXA 4XUIA 4X6HA 3QSDA 2P86A 3LXSA 1MIRA 4BSQA 4CZWA 2ACTA 3ZUAA 2XU3A 3PBHA 4FK5A 4YVAA 3IEJA 4XR7A 3K8UA 1MEGA 4YYVA 4PI3A 3NHEA 2DCAA 2XU5A 4I05A 3N3GA 5CHTA 3MORA 4W5CA 1YALA 1PPOA 3MHHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3H7D A;  3PDF A;  1CS8 A;  1Q6K A;  4N8W A;  1M6D A;  1KFX L;  2CB5 A;  3BOW A;  3PW3 A;  3P5X A;  3KKU A;  1U9X A;  2OP3 A;  1AU0 A;  3H6S A;  1ICF A;  4MSX A;  1MS6 A;  2F7D A;  2G6D A;  1BP4 A;  2WBF X;  4PP1 A;  4OEL A;  4P6G A;  3OVX A;  3IUT A;  2R9C A;  2NQI A;  3HHI A;  4QRX A;  3D6S A;  4N79 A;  1F2A A;  4W5B A;  4AXL A;  2ATO A;  4YV8 A;  2DCC A;  3I3T A;  4CDE B;  1NLJ A;  2DC8 A;  3O1G A;  2FQ9 A;  2AVW A;  4Q8G A;  1STF E;  1SNK A;  4FJC A;  1EWM A;  2ARY A;  3N4C A;  2R9F A;  1GCB A;  3HWN A;  1BQI A;  3CH3 X;  1YVB A;  2DZZ A;  2YJ9 A;  6PAD A;  2B1N A;  5F02 A;  1KHQ A;  3F75 A;  3RVV A;  4MZO A;  3V6C A;  2GFO A;  3F5V A;  3KWB X;  2HD5 A;  4AXM A;  1PIP A;  1NB5 A;  1CPJ A;  2Y5B A;  3N3K A;  4YYR A;  3IHP A;  1KHP A;  4X6J A;  1QOL A;  1EWP A;  3CH2 X;  2E00 A;  1ITO A;  3RVW A;  2AU1 A;  2DC9 A;  4PP2 E;  1NB3 A;  4N4Z A;  3OVZ A;  7PCK A;  2FT2 A;  3LFY A;  1TL9 A;  3I06 A;  5FPW A;  2JQG R;  1TU6 A;  1AEC A;  4YYU A;  1K3B B;  1CVZ A;  5A24 A;  9PAP A;  3IOQ A;  4I04 A;  4KLB A;  1KXR A;  4CDD B;  2G8E A;  2PAD A;  2FRQ A;  2C0Y A;  4BQV A;  3HD3 A;  3BWK A;  1TLO A;  2VHF A;  1QMY A;  3B79 A;  4DMY A;  1MHW A;  1PCI A;  4PAD A;  1CSB B;  2DJG B;  3H8B A;  3OIS A;  3AI8 A;  2YJ8 A;  3S3R A;  2GHU A;  1BY8 A;  2H7J A;  1IWD A;  5JA7 A;  1VJV A;  2R9N A;  2AYO A;  1F2B A;  1KFU L;  1PPD A;  4QRV A;  1YK8 A;  3BC3 A;  1GLO A;  2BDL A;  1NPZ A;  4ZUX U;  2B1M A;  1U9W A;  1CQD A;  1FH0 A;  3C9E A;  1PBH A;  2XU4 A;  1XKG A;  1ME3 A;  2E01 A;  2HH5 A;  1F29 A;  2NQD B;  1F2C A;  1ATK A;  1CV8 A;  2DJF B;  2CIO A;  2FUD A;  3CBJ A;  3OF8 A;  1CB5 A;  1THE A;  2FRA A;  1EWL A;  2R9O A;  5PAD A;  1O0E A;  4YYQ A;  4BPV A;  3H89 A;  2R6N A;  3WXG A;  3MHS A;  2DCB A;  2PBH A;  4QH6 A;  1DEU A;  1VSN A;  3P5V A;  4YYW A;  2P7U A;  3GCB A;  2FO5 A;  3IMA A;  1MDW A;  4BS5 A;  4WA6 A;  1NL6 A;  1CTE A;  5CVN B;  2O6X A;  3P5W A;  1AYV A;  3K24 A;  1AIM A;  1YT7 A;  2E02 A;  1NQC A;  3P5U A;  1ME4 A;  1QXP A;  4RY2 A;  1X9Y A;  1POP A;  3MTN A;  2R9M A;  3IV2 A;  1AYU A;  1Y4H A;  1U5I A;  1EF7 A;  4YYS A;  3BCN A;  1PPP A;  1U9Q X;  1JQP A;  2NQA A;  5EGW A;  4CDF B;  4X6I A;  3BPM A;  1YK7 A;  5J94 A;  4CDC B;  1AYW A;  2P0R A;  2DCD A;  2AUZ A;  2YJ2 A;  2PNS A;  2HXZ A;  2DZY A;  1ZCM A;  5JH3 A;  2DC7 A;  3H8C A;  4I07 A;  2PRE A;  2JQF R;  1PAD A;  4QBB A;  4MZS A;  5K16 A;  3USV A;  5CHV A;  1MEM A;  3CBK A;  3BPF A;  1PPN A;  2AS8 A;  2BDZ A;  2DC6 A;  2FYE A;  4QRG A;  2F1G A;  4OEM A;  2G8J A;  1GEC E;  1S4V A;  3DF0 A;  5CVO B;  3OF9 A;  1SP4 B;  3RVX A;  2YJC A;  2AUX A;  4K7C A;  8PCH A;  3E1Z B;  4P6E A;  3HHA A;  3PNR A;  4FIP A;  1U9V A;  1PXV A;  2AIM A;  2IPP B;  2IBI A;  3S3Q A;  1CJL A;  2XU1 A;  3O0U A;  2VHS A;  1PE6 A;  1A6R A;  1QDQ A;  1DF0 A;  5EF4 A;  1AU2 A;  2E03 A;  3KW9 A;  1AU4 A;  3U8E A;  3WXF A;  1GMY A;  1ZIV A;  3QJ3 A;  3ERV A;  2OUL A;  1BGO A;  3V6E A;  2OZ2 A;  4W4U A;  2AYN A;  1HUC B;  1Y08 A;  1EWO A;  4BS6 A;  2YJB A;  2G7Y A;  3K9M A;  3KX1 A;  1AU3 A;  3QT4 A;  3KSE A;  4DMX A;  2Y6E A;  4HWY A;  3WXE A;  2HHN A;  4G54 A;  4Q8H A;  2NQG A;  3M99 A;  3KWZ A;  3KFQ A;  2FTD A;  5CVM A;  3TNX A;  4XUI A;  4X6H A;  3QSD A;  2P86 A;  3LXS A;  1MIR A;  4BSQ A;  4CZW A;  2ACT A;  3ZUA A;  2XU3 A;  3PBH A;  4FK5 A;  4YVA A;  3IEJ A;  4XR7 A;  3K8U A;  1MEG A;  4YYV A;  4PI3 A;  3NHE A;  2DCA A;  2XU5 A;  4I05 A;  3N3G A;  5CHT A;  3MOR A;  4W5C A;  1YAL A;  1PPO A;  3MHH A; 
#chains in the Genus database with same CATH topology
 3H7D A;  3PDF A;  1CS8 A;  1Q6K A;  4N8W A;  1M6D A;  3TRK A;  1KFX L;  2CB5 A;  4OVZ A;  3BOW A;  4PT5 A;  3PW3 A;  3P5X A;  3KKU A;  1U9X A;  2OP3 A;  3PHU A;  1AU0 A;  3H6S A;  1ICF A;  4MSX A;  1MS6 A;  4GUA A;  2F7D A;  3BB7 A;  2G6D A;  1BP4 A;  2WBF X;  4PP1 A;  4OEL A;  4P6G A;  3OVX A;  3IUT A;  5JZE A;  3ZNH A;  2R9C A;  2NQI A;  4RKX A;  3HHI A;  3OQC A;  2AGA A;  4QRX A;  3D6S A;  4N79 A;  1F2A A;  4W5B A;  4AXL A;  2ATO A;  4YV8 A;  2DCC A;  3I3T A;  4CDE B;  1NLJ A;  2DC8 A;  3O1G A;  2FQ9 A;  2AVW A;  4Q8G A;  4OVZ B;  1STF E;  1SNK A;  4FJC A;  1EWM A;  2ARY A;  3N4C A;  2R9F A;  1GCB A;  2Z84 A;  3HWN A;  1BQI A;  3CH3 X;  2JTC A;  1YVB A;  2DZZ A;  2YJ9 A;  6PAD A;  2B1N A;  5F02 A;  1KHQ A;  3F75 A;  3RVV A;  4MZO A;  3V6C A;  2BU3 A;  2GFO A;  3F5V A;  3KWB X;  2HD5 A;  4RF1 A;  4AXM A;  1PIP A;  1NB5 A;  1CPJ A;  2Y5B A;  3N3K A;  4YYR A;  3IHP A;  1KHP A;  4X6J A;  1QOL A;  2DOS A;  3PRM A;  1EWP A;  4R3D A;  3O65 A;  3CH2 X;  2E00 A;  4MM3 B;  3PSE A;  3E9S A;  1ITO A;  3RVW A;  2AU1 A;  2FE8 A;  2DC9 A;  4PP2 E;  1NB3 A;  4N4Z A;  3OVZ A;  7PCK A;  2FT2 A;  3LFY A;  1TL9 A;  3I06 A;  5FPW A;  2JQG R;  1TU6 A;  1AEC A;  3MJ5 A;  4YYU A;  1K3B B;  1CVZ A;  4D8I A;  5A24 A;  9PAP A;  4MI7 A;  3IOQ A;  4I04 A;  4KLB A;  1KXR A;  4CDD B;  2G8E A;  2PAD A;  2FRQ A;  2C0Y A;  4BQV A;  3HD3 A;  3BWK A;  1TLO A;  2VHF A;  1QMY A;  3B79 A;  3PRP A;  4DMY A;  1MHW A;  1PCI A;  4HXD B;  4PAD A;  1CSB B;  2DJG B;  3H8B A;  3OIS A;  3AI8 A;  2YJ8 A;  3S3R A;  2GHU A;  1BY8 A;  2H7J A;  1IWD A;  4BOS A;  3B21 A;  5JA7 A;  1VJV A;  2R9N A;  2AYO A;  1F2B A;  5EZQ A;  1KFU L;  1PPD A;  4QRV A;  1YK8 A;  3BC3 A;  3W31 A;  1GLO A;  2BDL A;  1NPZ A;  4ZUX U;  2B1M A;  1U9W A;  1CQD A;  1FH0 A;  3C9E A;  1PBH A;  2XU4 A;  1XKG A;  1ME3 A;  2E01 A;  2HH5 A;  1F29 A;  3MP2 A;  5E6J A;  1YZB A;  2NQD B;  1F2C A;  1ATK A;  1CV8 A;  2DJF B;  2CIO A;  2FUD A;  3CBJ A;  3OF8 A;  1CB5 A;  1THE A;  2BTW A;  2FRA A;  1EWL A;  2R9O A;  4REZ A;  5PAD A;  2UZJ A;  1O0E A;  4YYQ A;  4BPV A;  3H89 A;  2R6N A;  3WXG A;  2J7Q C;  3MHS A;  2DCB A;  2PBH A;  4QH6 A;  1DEU A;  2J7Q A;  1VSN A;  3P5V A;  4YYW A;  3RNV A;  2P7U A;  3GCB A;  3PT2 A;  2FO5 A;  4XZX A;  3IMA A;  1MDW A;  4BS5 A;  4WA6 A;  1NL6 A;  1CTE A;  5CVN B;  2O6X A;  2JRI A;  3P5W A;  1AYV A;  2BTW B;  3K24 A;  5EZS A;  1AIM A;  1YT7 A;  2E02 A;  1NQC A;  3P5U A;  1ME4 A;  1QXP A;  4RY2 A;  4BOQ A;  1X9Y A;  1POP A;  3MTN A;  2R9M A;  3IV2 A;  1AYU A;  3MTV A;  1Y4H A;  1U5I A;  1EF7 A;  4YYS A;  3BCN A;  1PPP A;  1U9Q X;  3C0R A;  1JQP A;  3PHX A;  2NQA A;  4IUM A;  5EGW A;  4CDF B;  4X6I A;  3BPM A;  1YK7 A;  3IFU A;  5J94 A;  4CDC B;  1AYW A;  2P0R A;  2DCD A;  2AUZ A;  2YJ2 A;  2PNS A;  2HXZ A;  4BOP A;  1DKI A;  2DZY A;  1ZCM A;  5JH3 A;  2DC7 A;  3H8C A;  4I07 A;  2PRE A;  2JQF R;  1PAD A;  4QBB A;  4MZS A;  5K16 A;  4WUR A;  3USV A;  5CHV A;  1MEM A;  3CBK A;  3BPF A;  1PPN A;  2AS8 A;  2BDZ A;  3PHW A;  4RF0 A;  2DC6 A;  3BY4 A;  2FYE A;  4QRG A;  2F1G A;  4OEM A;  2G8J A;  4P16 A;  1GEC E;  1S4V A;  3DF0 A;  5CVO B;  3OF9 A;  1SP4 B;  3RVX A;  2YJC A;  2AUX A;  4K7C A;  8PCH A;  3E1Z B;  4P6E A;  3HHA A;  3PNR A;  4FIP A;  4RNA A;  4D8B A;  1U9V A;  1PXV A;  2AIM A;  2IPP B;  2IBI A;  3S3Q A;  1CJL A;  2XU1 A;  3O0U A;  4A5U A;  2VHS A;  1PE6 A;  1A6R A;  1QDQ A;  1DF0 A;  5EF4 A;  1AU2 A;  2E03 A;  3KW9 A;  1AU4 A;  3U8E A;  3WXF A;  1GMY A;  1ZIV A;  3QJ3 A;  3ERV A;  3TMP A;  2OUL A;  1BGO A;  3V6E A;  2OZ2 A;  4W4U A;  2AYN A;  1HUC B;  1Y08 A;  1EWO A;  4BS6 A;  2YJB A;  4IP3 A;  2G7Y A;  3K9M A;  3KX1 A;  1AU3 A;  3QT4 A;  3KSE A;  4DMX A;  1UKF A;  2Y6E A;  4HWY A;  3WXE A;  2HHN A;  3BBA A;  3W30 A;  4BOU A;  4G54 A;  4Q8H A;  4M0W A;  2NQG A;  3M99 A;  3KWZ A;  3KFQ A;  2FTD A;  5CVM A;  3TNX A;  4XUI A;  4ZTB A;  2HWK A;  4X6H A;  3QSD A;  4BOZ A;  2P86 A;  3LXS A;  1MIR A;  4BSQ A;  4CZW A;  2ACT A;  3ZUA A;  4D8E A;  2XU3 A;  3PBH A;  4FK5 A;  4YVA A;  5KO3 A;  3IEJ A;  4XR7 A;  3K8U A;  1MEG A;  4YYV A;  4PI3 A;  3NHE A;  2DCA A;  1PVJ A;  2XU5 A;  4I05 A;  3N3G A;  5CHT A;  3MOR A;  4OW0 A;  4W5C A;  1YAL A;  1PPO A;  3MHH A; 
#chains in the Genus database with same CATH homology
 3H7D A;  3PDF A;  1CS8 A;  1Q6K A;  4N8W A;  1M6D A;  1KFX L;  2CB5 A;  3BOW A;  3PW3 A;  3P5X A;  3KKU A;  1U9X A;  2OP3 A;  1AU0 A;  3H6S A;  1ICF A;  4MSX A;  1MS6 A;  2F7D A;  2G6D A;  1BP4 A;  2WBF X;  4PP1 A;  4OEL A;  4P6G A;  3OVX A;  3IUT A;  2R9C A;  2NQI A;  1E2T A;  3HHI A;  4QRX A;  3D6S A;  4N79 A;  1F2A A;  4W5B A;  4AXL A;  2ATO A;  4YV8 A;  2DCC A;  3I3T A;  4CDE B;  1NLJ A;  2DC8 A;  3O1G A;  2FQ9 A;  2AVW A;  4Q8G A;  1STF E;  1SNK A;  4FJC A;  1EWM A;  2ARY A;  3N4C A;  2R9F A;  1GCB A;  3HWN A;  1BQI A;  3CH3 X;  1YVB A;  2DZZ A;  2YJ9 A;  6PAD A;  2B1N A;  5F02 A;  1KHQ A;  3F75 A;  3RVV A;  4MZO A;  3V6C A;  2GFO A;  3F5V A;  3KWB X;  2HD5 A;  4AXM A;  1PIP A;  1NB5 A;  1CPJ A;  2Y5B A;  3N3K A;  4YYR A;  3IHP A;  1KHP A;  4X6J A;  1QOL A;  1EWP A;  1W4T A;  3CH2 X;  1GX3 A;  2E00 A;  1ITO A;  3RVW A;  2AU1 A;  4NV8 A;  2DC9 A;  3LTW A;  4PP2 E;  1NB3 A;  4N4Z A;  3OVZ A;  7PCK A;  2FT2 A;  3LFY A;  1TL9 A;  3I06 A;  5FPW A;  2JQG R;  1TU6 A;  1AEC A;  4YYU A;  1K3B B;  1CVZ A;  5A24 A;  9PAP A;  3IOQ A;  4I04 A;  4KLB A;  1KXR A;  4CDD B;  2G8E A;  2PAD A;  2FRQ A;  2C0Y A;  4BQV A;  3HD3 A;  3BWK A;  1TLO A;  2VHF A;  4GUZ A;  1QMY A;  3B79 A;  4DMY A;  1MHW A;  1PCI A;  4PAD A;  1CSB B;  2DJG B;  3H8B A;  3OIS A;  3AI8 A;  2YJ8 A;  3S3R A;  2GHU A;  1BY8 A;  2H7J A;  1IWD A;  5JA7 A;  1VJV A;  2R9N A;  2AYO A;  1F2B A;  1KFU L;  1PPD A;  4QRV A;  1YK8 A;  3BC3 A;  1GLO A;  2BDL A;  1NPZ A;  4ZUX U;  2B1M A;  1U9W A;  1CQD A;  1FH0 A;  3C9E A;  1PBH A;  2XU4 A;  1XKG A;  1ME3 A;  2E01 A;  2HH5 A;  1F29 A;  2NQD B;  1F2C A;  4NV7 A;  1ATK A;  1CV8 A;  2DJF B;  2CIO A;  2FUD A;  3CBJ A;  3OF8 A;  1CB5 A;  1THE A;  2FRA A;  1EWL A;  2R9O A;  5PAD A;  1O0E A;  4YYQ A;  4BPV A;  3H89 A;  2R6N A;  3WXG A;  3MHS A;  2DCB A;  2PBH A;  4QH6 A;  1DEU A;  1VSN A;  3P5V A;  4YYW A;  2P7U A;  3GCB A;  2FO5 A;  3IMA A;  1MDW A;  4BS5 A;  4WA6 A;  1NL6 A;  1CTE A;  5CVN B;  2O6X A;  3P5W A;  1AYV A;  3K24 A;  1AIM A;  1YT7 A;  2E02 A;  1NQC A;  3P5U A;  1ME4 A;  1QXP A;  4RY2 A;  4BGF A;  1X9Y A;  1POP A;  3MTN A;  2R9M A;  3IV2 A;  1AYU A;  1Y4H A;  1U5I A;  1EF7 A;  4YYS A;  3BCN A;  1PPP A;  1U9Q X;  1JQP A;  2NQA A;  5EGW A;  4CDF B;  4X6I A;  3BPM A;  1YK7 A;  5J94 A;  4CDC B;  1AYW A;  2P0R A;  2DCD A;  2AUZ A;  2YJ2 A;  2PNS A;  2HXZ A;  2DZY A;  1ZCM A;  5JH3 A;  2DC7 A;  3H8C A;  4I07 A;  2PRE A;  2JQF R;  1PAD A;  4QBB A;  4MZS A;  5K16 A;  3USV A;  5CHV A;  1MEM A;  3CBK A;  3BPF A;  1PPN A;  2AS8 A;  2BDZ A;  2BSZ A;  2DC6 A;  2FYE A;  4QRG A;  2F1G A;  4OEM A;  4B55 A;  2G8J A;  1GEC E;  1S4V A;  3DF0 A;  5CVO B;  3OF9 A;  1SP4 B;  3RVX A;  2YJC A;  2AUX A;  4K7C A;  8PCH A;  3E1Z B;  4P6E A;  3HHA A;  3PNR A;  4FIP A;  1U9V A;  1PXV A;  2AIM A;  2IPP B;  2IBI A;  3S3Q A;  1CJL A;  2XU1 A;  3O0U A;  2VHS A;  1PE6 A;  1A6R A;  1QDQ A;  1DF0 A;  3D9W A;  5EF4 A;  1AU2 A;  2E03 A;  3KW9 A;  1AU4 A;  1W6F A;  3U8E A;  3WXF A;  1GMY A;  1ZIV A;  3QJ3 A;  3ERV A;  2OUL A;  1BGO A;  3V6E A;  4C5P A;  2OZ2 A;  4W4U A;  2AYN A;  1W5R A;  1HUC B;  1Y08 A;  1EWO A;  4BS6 A;  2YJB A;  2G7Y A;  3K9M A;  3KX1 A;  1AU3 A;  3QT4 A;  3KSE A;  4DMX A;  2VFB A;  2VFC A;  2Y6E A;  4HWY A;  3WXE A;  2HHN A;  4G54 A;  4Q8H A;  2NQG A;  3M99 A;  3KWZ A;  3KFQ A;  2FTD A;  5CVM A;  3TNX A;  4XUI A;  4X6H A;  3QSD A;  2P86 A;  3LXS A;  1MIR A;  4BSQ A;  4CZW A;  2ACT A;  3ZUA A;  2XU3 A;  3PBH A;  4FK5 A;  4YVA A;  3IEJ A;  4XR7 A;  3K8U A;  1MEG A;  4YYV A;  4PI3 A;  3NHE A;  2DCA A;  2XU5 A;  4I05 A;  3N3G A;  5CHT A;  3MOR A;  4W5C A;  1YAL A;  1PPO A;  3MHH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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