3KKUA

Cruzain in complex with a non-covalent ligand
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
215
structure length
214
Chain Sequence
APAAVDWRARGAVTAVKDQGQCGSCWAFSAIGNVECQWFLAGHPLTNLSEQMLVSCDKTDSGCSGGLMNNAFEWIVQENNGAVYTDSYPYASGEGISPPCTTSGHTVGATITGHVELPQDEAQIAAWLAVNGPVAVAVDASSWMTYTGGVMTSCVSEQLDHGVLLVGYNDSAAVPYWIIKNSWTTQWGEEGYIRIAKGSNQCLVKEEASSAVVG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Complementarity between a docking and a high-throughput screen in discovering new cruzain inhibitors.
pubmed doi rcsb
molecule tags Hydrolase
source organism Trypanosoma cruzi
molecule keywords Cruzipain
total genus 70
structure length 214
sequence length 215
ec nomenclature ec 3.4.22.51: Cruzipain.
pdb deposition date 2009-11-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 3kkuA00
2OULA 1Q6KA 3ERVA 3H7DA 3IEJA 3K8UA 3QSDA 1TL9A 4AXMA 2PNSA 2AU1A 3BC3A 2E03A 2DJGB 2HHNA 3MHHA 2B1NA 2G7YA 1MEMA 2ACTA 2E00A 2DCCA 2HD5A 4N8WA 3S3QA 3IV2A 1MEGA 1U5IA 1Y08A 2FQ9A 5EF4A 5F02A 4BS6A 3QJ3A 5K16A 3V6EA 4CZWA 1MDWA 2R9FA 2DC7A 4CDFB 3IHPA 3P5XA 7PCKA 5EGWA 4N79A 3AI8A 4OELA 3PW3A 1U9XA 3PDFA 2Y6EA 1QMYA 3LXSA 1MHWA 4MZSA 5PADA 2YJ8A 3K9MA 4CDDB 4X6JA 2G6DA 1POPA 1BQIA 1SNKA 2XU1A 1GLOA 4N4ZA 3OF8A 3CBJA 1CPJA 1YVBA 1GMYA 3F5VA 2FT2A 1PPNA 2FYEA 9PAPA 1STFE 3WXFA 4KLBA 1CVZA 1TU6A 2FRQA 3MTNA 2VHSA 3N4CA 3DF0A 1AYWA 2CIOA 1NB3A 8PCHA 1ZIVA 4XUIA 2PREA 1QXPA 1PPPA 5A24A 2O6XA 1CJLA 2F1GA 1ME3A 3B79A 1KHQA 1AU0A 2R9OA 3HD3A 3CH3X 2C0YA 3IUTA 4W5CA 1ME4A 5CVMA 1QOLA 3NHEA 5J94A 1AIMA 2IBIA 1AYVA 3CH2X 5CVNB 1QDQA 2DZZA 2WBFX 3KFQA 4DMXA 2GFOA 1KFXL 2AYOA 2P0RA 2BDZA 1YT7A 2G8EA 2PADA 2JQFR 3OISA 1Y4HA 3I06A 2DCAA 3N3GA 3P5VA 4CDCB 1U9WA 1PBHA 1PPDA 1GECE 1AU2A 3O0UA 2F7DA 4QRGA 4ZUXU 4FJCA 1YK8A 4QRXA 1CB5A 4YVAA 2BDLA 3C9EA 1NQCA 3PNRA 2JQGR 2FO5A 2R9MA 1BY8A 4X6IA 1K3BB 4G54A 1DF0A 2OP3A 4MSXA 2P7UA 3WXEA 1PPOA 2YJCA 2H7JA 1U9QX 2YJ2A 1PXVA 4HWYA 4MZOA 2XU4A 1VJVA 1SP4B 4Q8GA 2R9NA 1PIPA 2FRAA 4WA6A 3KWBX 1THEA 2NQIA 2P86A 1X9YA 2B1MA 4PADA 1KFUL 2AUXA 2YJBA 2DCBA 1VSNA 3H8CA 3ZUAA 4W5BA 3GCBA 1ATKA 1EWOA 4QH6A 1CV8A 3CBKA 3KKUA 1PE6A 3KX1A 4XR7A 3IOQA 4BPVA 2AUZA 2AYNA 2NQAA 1HUCB 1ZCMA 5CHVA 3USVA 1CTEA 2OZ2A 3K24A 5CHTA 2NQGA 3I3TA 2FUDA 4CDEB 2DZYA 5FPWA 3OVZA 3F75A 3LFYA 3O1GA 3WXGA 3BOWA 4PI3A 3IMAA 4PP2E 2G8JA 2XU5A 3TNXA 1PCIA 2DC8A 3N3KA 4OEMA 3RVWA 1AECA 1AU4A 1F29A 3D6SA 1F2AA 2CB5A 1AU3A 4RY2A 3HWNA 4YYVA 2DCDA 4YYQA 3BCNA 4YYRA 4BQVA 4I04A 3KWZA 1BGOA 1EWLA 1ICFA 4K7CA 1EWMA 2Y5BA 2HXZA 3OF9A 3MHSA 2YJ9A 3H6SA 5JH3A 4PP1A 3BWKA 4QBBA 1MIRA 2AIMA 5CVOB 1EF7A 2AVWA 1DEUA 3KSEA 1NL6A 3RVVA 2AS8A 4FK5A 1CS8A 3E1ZB 1O0EA 1NPZA 2FTDA 1AYUA 3PBHA 4BS5A 1KHPA 1KXRA 4YYUA 1XKGA 3P5WA 1YK7A 4I07A 2PBHA 3OVXA 1U9VA 2DC6A 3MORA 4FIPA 3V6CA 1A6RA 4W4UA 2XU3A 2R9CA 1IWDA 4I05A 3P5UA 2GHUA 1EWPA 2VHFA 1FH0A 4DMYA 3BPMA 1TLOA 3H89A 2ARYA 2DC9A 1NLJA 1NB5A 2R6NA 1JQPA 3M99A 3QT4A 2NQDB 1CSBB 4P6GA 1F2CA 3RVXA 4YV8A 2E01A 3KW9A 2E02A 5JA7A 4Q8HA 3H8BA 1PADA 3HHIA 4BSQA 4QRVA 1MS6A 2ATOA 1M6DA 3S3RA 1YALA 4X6HA 2IPPB 4P6EA 1ITOA 1CQDA 1GCBA 3HHAA 6PADA 4YYSA 1F2BA 2DJFB 3U8EA 4AXLA 2HH5A 1BP4A 3BPFA 4YYWA 1S4VA
chains in the Genus database with same CATH superfamily
2OULA 1Q6KA 2DOSA 2JTCA 3OQCA 3W30A 3ERVA 3H7DA 3RNVA 3IEJA 3K8UA 3QSDA 1TL9A 4AXMA 3W31A 2PNSA 2AU1A 3BC3A 2E03A 2DJGB 2HHNA 3MHHA 2B1NA 3MP2A 2G7YA 1MEMA 2ACTA 5KO3A 2E00A 2DCCA 2HD5A 4N8WA 3S3QA 3IV2A 4BOSA 1MEGA 1U5IA 1Y08A 2FQ9A 5EF4A 5F02A 4BS6A 3QJ3A 5K16A 3E9SA 3V6EA 4CZWA 1MDWA 2R9FA 2DC7A 4CDFB 3IHPA 3P5XA 7PCKA 5EGWA 4N79A 3AI8A 4OELA 3PW3A 1U9XA 3PDFA 2Y6EA 1QMYA 3LXSA 4PT5A 1MHWA 4D8BA 4MZSA 5PADA 2YJ8A 3K9MA 4CDDB 4X6JA 2G6DA 1POPA 1BQIA 1SNKA 2XU1A 1GLOA 4N4ZA 3OF8A 3CBJA 1CPJA 1YVBA 1GMYA 3F5VA 2FT2A 1PPNA 2FYEA 9PAPA 1STFE 3WXFA 4KLBA 1CVZA 1TU6A 2FRQA 3MTNA 2VHSA 3N4CA 3DF0A 1UKFA 1AYWA 2CIOA 1NB3A 8PCHA 4MI7A 1ZIVA 4XUIA 2PREA 1QXPA 1PPPA 5A24A 2O6XA 4HXDB 1CJLA 2F1GA 1ME3A 3B79A 4GUAA 1KHQA 1AU0A 2R9OA 3HD3A 3CH3X 2C0YA 3IUTA 4W5CA 1ME4A 5CVMA 1QOLA 3NHEA 5J94A 2Z84A 1AIMA 5JZEA 2IBIA 2HWKA 1AYVA 3CH2X 5CVNB 1QDQA 2DZZA 5EZSA 2WBFX 3KFQA 4DMXA 2GFOA 3BBAA 1KFXL 2AYOA 2P0RA 2BDZA 1YT7A 2G8EA 2PADA 4IUMA 2JQFR 3OISA 1Y4HA 3I06A 4REZA 2DCAA 3N3GA 3P5VA 4CDCB 1U9WA 1PBHA 4ZTBA 3TMPA 1PPDA 1GECE 1AU2A 3O0UA 2F7DA 4QRGA 4ZUXU 4FJCA 1PVJA 1YK8A 4QRXA 1CB5A 2UZJA 2AGAA 4YVAA 2BDLA 3C9EA 1NQCA 3PNRA 2JQGR 2FO5A 2R9MA 1BY8A 4X6IA 1K3BB 4G54A 3PHWA 1DF0A 2OP3A 4MSXA 2P7UA 3WXEA 1PPOA 2YJCA 2H7JA 1U9QX 2YJ2A 1PXVA 4HWYA 4MZOA 2XU4A 1VJVA 1SP4B 4BOUA 4P16A 4Q8GA 4RKXA 2R9NA 4M0WA 1PIPA 2FRAA 4WA6A 3KWBX 1THEA 2NQIA 2P86A 1X9YA 2B1MA 4PADA 3TRKA 1KFUL 2AUXA 1YZBA 2YJBA 2DCBA 1VSNA 3H8CA 3ZUAA 4W5BA 3GCBA 4RF0A 1ATKA 1EWOA 4QH6A 1CV8A 3CBKA 3KKUA 1PE6A 3KX1A 4XR7A 3IOQA 4BPVA 3C0RA 2AUZA 2AYNA 2NQAA 1HUCB 1ZCMA 5CHVA 3USVA 4D8IA 1CTEA 2OZ2A 3K24A 5CHTA 2NQGA 3PSEA 3I3TA 2FUDA 4CDEB 2DZYA 4BOZA 1DKIA 5FPWA 3OVZA 3F75A 3LFYA 3O1GA 3WXGA 3BOWA 4PI3A 3IMAA 4PP2E 2G8JA 2XU5A 3TNXA 1PCIA 2DC8A 3N3KA 4BOQA 4OEMA 3RVWA 1AECA 1AU4A 2J7QA 1F29A 3D6SA 1F2AA 2CB5A 1AU3A 4RY2A 3HWNA 4RF1A 4YYVA 2DCDA 4YYQA 3BCNA 4YYRA 4BQVA 4I04A 3KWZA 3PHUA 1BGOA 1EWLA 3ZNHA 1ICFA 4K7CA 1EWMA 2Y5BA 2FE8A 2HXZA 3OF9A 3MHSA 2YJ9A 3H6SA 4XZXA 5JH3A 4PP1A 3BWKA 4QBBA 3IFUA 1MIRA 2AIMA 4BOPA 5CVOB 1EF7A 2AVWA 1DEUA 3KSEA 3BY4A 1NL6A 3RVVA 2AS8A 4FK5A 1CS8A 3E1ZB 1O0EA 5E6JA 1NPZA 2FTDA 1AYUA 3PBHA 4BS5A 1KHPA 1KXRA 4YYUA 1XKGA 3PHXA 3PRMA 2BTWA 3P5WA 1YK7A 4I07A 2PBHA 4R3DA 3OVXA 1U9VA 2DC6A 3MORA 4FIPA 3V6CA 1A6RA 4W4UA 2XU3A 2R9CA 3B21A 1IWDA 3PT2A 2BTWB 4I05A 3P5UA 2GHUA 1EWPA 2VHFA 1FH0A 4DMYA 3BPMA 3MTVA 1TLOA 3H89A 2ARYA 3PRPA 2J7QC 2DC9A 1NLJA 4MM3B 1NB5A 2R6NA 1JQPA 3M99A 2BU3A 3QT4A 4OW0A 2NQDB 4OVZA 5EZQA 3O65A 1CSBB 4P6GA 1F2CA 3RVXA 4YV8A 3MJ5A 2E01A 3KW9A 2E02A 5JA7A 4OVZB 4A5UA 2JRIA 4IP3A 4Q8HA 3H8BA 1PADA 3HHIA 4BSQA 4D8EA 4QRVA 1MS6A 2ATOA 3BB7A 1M6DA 3S3RA 1YALA 4WURA 4X6HA 2IPPB 4P6EA 1ITOA 1CQDA 1GCBA 3HHAA 6PADA 4YYSA 1F2BA 2DJFB 3U8EA 4RNAA 4AXLA 2HH5A 1BP4A 3BPFA 4YYWA 1S4VA
chains in the Genus database with same CATH topology
2OULA 1Q6KA 4B55A 3ERVA 3H7DA 3IEJA 3K8UA 3QSDA 3LTWA 1TL9A 4AXMA 2PNSA 2AU1A 3BC3A 2E03A 2DJGB 2HHNA 3MHHA 2B1NA 4NV7A 2G7YA 1MEMA 2ACTA 2E00A 2DCCA 2VFBA 2HD5A 4N8WA 3S3QA 3IV2A 1MEGA 1U5IA 1Y08A 2FQ9A 5EF4A 5F02A 4BS6A 3QJ3A 5K16A 3V6EA 4CZWA 1MDWA 1W6FA 2R9FA 2DC7A 4CDFB 3IHPA 3P5XA 7PCKA 5EGWA 4N79A 3AI8A 4OELA 3PW3A 1U9XA 3PDFA 2Y6EA 1QMYA 3LXSA 1MHWA 4MZSA 5PADA 2YJ8A 3K9MA 4CDDB 4X6JA 2G6DA 1POPA 1BQIA 1SNKA 2XU1A 1GLOA 4N4ZA 3OF8A 3CBJA 1CPJA 1YVBA 1GMYA 3F5VA 2FT2A 1PPNA 2FYEA 9PAPA 1STFE 3WXFA 4KLBA 1CVZA 1TU6A 2FRQA 3MTNA 2VHSA 3N4CA 3DF0A 1AYWA 2CIOA 1NB3A 8PCHA 1ZIVA 4XUIA 2PREA 1QXPA 1PPPA 4NV8A 5A24A 2O6XA 1CJLA 2F1GA 1ME3A 3B79A 1KHQA 1AU0A 2R9OA 3HD3A 3CH3X 2C0YA 3IUTA 4W5CA 1ME4A 5CVMA 1QOLA 3NHEA 5J94A 2BSZA 1AIMA 2IBIA 1AYVA 3CH2X 5CVNB 1QDQA 2DZZA 2WBFX 3KFQA 4DMXA 2GFOA 1KFXL 2AYOA 2P0RA 2BDZA 1YT7A 2G8EA 2PADA 2JQFR 3OISA 1Y4HA 3I06A 2DCAA 3N3GA 3P5VA 4CDCB 1U9WA 1PBHA 1PPDA 1GECE 1AU2A 3O0UA 2F7DA 4QRGA 4ZUXU 4FJCA 1YK8A 1E2TA 4QRXA 1CB5A 4YVAA 2BDLA 3C9EA 1NQCA 1W4TA 3PNRA 2JQGR 2FO5A 2R9MA 1BY8A 4X6IA 1K3BB 4G54A 1DF0A 2OP3A 4MSXA 2P7UA 3WXEA 1PPOA 2YJCA 2H7JA 1U9QX 2YJ2A 1PXVA 4HWYA 4MZOA 2XU4A 1VJVA 1SP4B 4Q8GA 2R9NA 1PIPA 2FRAA 4WA6A 3KWBX 1THEA 2NQIA 2P86A 1X9YA 2B1MA 4PADA 1KFUL 2AUXA 2YJBA 2DCBA 1VSNA 3H8CA 3ZUAA 4W5BA 3GCBA 1ATKA 1EWOA 4QH6A 1CV8A 3CBKA 3KKUA 1PE6A 3KX1A 4XR7A 3IOQA 4BPVA 2AUZA 2AYNA 2NQAA 1HUCB 1ZCMA 5CHVA 3USVA 1CTEA 2OZ2A 3K24A 5CHTA 2NQGA 3I3TA 2FUDA 4CDEB 2DZYA 5FPWA 3OVZA 3F75A 4BGFA 3LFYA 3O1GA 3WXGA 3BOWA 4PI3A 3IMAA 4PP2E 2G8JA 2XU5A 3TNXA 1PCIA 2DC8A 3N3KA 3D9WA 4OEMA 3RVWA 1AECA 1AU4A 1F29A 3D6SA 1F2AA 2CB5A 1AU3A 4RY2A 3HWNA 4YYVA 4C5PA 2DCDA 4YYQA 3BCNA 4YYRA 4BQVA 4I04A 3KWZA 1BGOA 1EWLA 1ICFA 4K7CA 1EWMA 2Y5BA 2HXZA 3OF9A 3MHSA 2YJ9A 3H6SA 5JH3A 4PP1A 3BWKA 4QBBA 1MIRA 2AIMA 5CVOB 1EF7A 2AVWA 1DEUA 3KSEA 1NL6A 3RVVA 2AS8A 4FK5A 1CS8A 3E1ZB 1O0EA 1NPZA 2FTDA 1AYUA 3PBHA 4BS5A 1KHPA 2VFCA 1KXRA 4YYUA 1XKGA 3P5WA 1YK7A 4I07A 2PBHA 3OVXA 1U9VA 2DC6A 3MORA 4FIPA 3V6CA 1A6RA 4W4UA 2XU3A 2R9CA 1IWDA 4I05A 3P5UA 2GHUA 1EWPA 2VHFA 1FH0A 4DMYA 3BPMA 1TLOA 3H89A 2ARYA 2DC9A 1NLJA 1NB5A 2R6NA 1JQPA 3M99A 3QT4A 2NQDB 1CSBB 4P6GA 1F2CA 3RVXA 4YV8A 2E01A 3KW9A 2E02A 5JA7A 4Q8HA 3H8BA 1PADA 3HHIA 4BSQA 4QRVA 1MS6A 2ATOA 1M6DA 3S3RA 1YALA 4X6HA 2IPPB 4P6EA 1ITOA 1CQDA 1GCBA 3HHAA 6PADA 1W5RA 4YYSA 1F2BA 2DJFB 3U8EA 4AXLA 2HH5A 4GUZA 1BP4A 3BPFA 1GX3A 4YYWA 1S4VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OUL A;  1Q6K A;  3ERV A;  3H7D A;  3IEJ A;  3K8U A;  3QSD A;  1TL9 A;  4AXM A;  2PNS A;  2AU1 A;  3BC3 A;  2E03 A;  2DJG B;  2HHN A;  3MHH A;  2B1N A;  2G7Y A;  1MEM A;  2ACT A;  2E00 A;  2DCC A;  2HD5 A;  4N8W A;  3S3Q A;  3IV2 A;  1MEG A;  1U5I A;  1Y08 A;  2FQ9 A;  5EF4 A;  5F02 A;  4BS6 A;  3QJ3 A;  5K16 A;  3V6E A;  4CZW A;  1MDW A;  2R9F A;  2DC7 A;  4CDF B;  3IHP A;  3P5X A;  7PCK A;  5EGW A;  4N79 A;  3AI8 A;  4OEL A;  3PW3 A;  1U9X A;  3PDF A;  2Y6E A;  1QMY A;  3LXS A;  1MHW A;  4MZS A;  5PAD A;  2YJ8 A;  3K9M A;  4CDD B;  4X6J A;  2G6D A;  1POP A;  1BQI A;  1SNK A;  2XU1 A;  1GLO A;  4N4Z A;  3OF8 A;  3CBJ A;  1CPJ A;  1YVB A;  1GMY A;  3F5V A;  2FT2 A;  1PPN A;  2FYE A;  9PAP A;  1STF E;  3WXF A;  4KLB A;  1CVZ A;  1TU6 A;  2FRQ A;  3MTN A;  2VHS A;  3N4C A;  3DF0 A;  1AYW A;  2CIO A;  1NB3 A;  8PCH A;  1ZIV A;  4XUI A;  2PRE A;  1QXP A;  1PPP A;  5A24 A;  2O6X A;  1CJL A;  2F1G A;  1ME3 A;  3B79 A;  1KHQ A;  1AU0 A;  2R9O A;  3HD3 A;  3CH3 X;  2C0Y A;  3IUT A;  4W5C A;  1ME4 A;  5CVM A;  1QOL A;  3NHE A;  5J94 A;  1AIM A;  2IBI A;  1AYV A;  3CH2 X;  5CVN B;  1QDQ A;  2DZZ A;  2WBF X;  3KFQ A;  4DMX A;  2GFO A;  1KFX L;  2AYO A;  2P0R A;  2BDZ A;  1YT7 A;  2G8E A;  2PAD A;  2JQF R;  3OIS A;  1Y4H A;  3I06 A;  2DCA A;  3N3G A;  3P5V A;  4CDC B;  1U9W A;  1PBH A;  1PPD A;  1GEC E;  1AU2 A;  3O0U A;  2F7D A;  4QRG A;  4ZUX U;  4FJC A;  1YK8 A;  4QRX A;  1CB5 A;  4YVA A;  2BDL A;  3C9E A;  1NQC A;  3PNR A;  2JQG R;  2FO5 A;  2R9M A;  1BY8 A;  4X6I A;  1K3B B;  4G54 A;  1DF0 A;  2OP3 A;  4MSX A;  2P7U A;  3WXE A;  1PPO A;  2YJC A;  2H7J A;  1U9Q X;  2YJ2 A;  1PXV A;  4HWY A;  4MZO A;  2XU4 A;  1VJV A;  1SP4 B;  4Q8G A;  2R9N A;  1PIP A;  2FRA A;  4WA6 A;  3KWB X;  1THE A;  2NQI A;  2P86 A;  1X9Y A;  2B1M A;  4PAD A;  1KFU L;  2AUX A;  2YJB A;  2DCB A;  1VSN A;  3H8C A;  3ZUA A;  4W5B A;  3GCB A;  1ATK A;  1EWO A;  4QH6 A;  1CV8 A;  3CBK A;  3KKU A;  1PE6 A;  3KX1 A;  4XR7 A;  3IOQ A;  4BPV A;  2AUZ A;  2AYN A;  2NQA A;  1HUC B;  1ZCM A;  5CHV A;  3USV A;  1CTE A;  2OZ2 A;  3K24 A;  5CHT A;  2NQG A;  3I3T A;  2FUD A;  4CDE B;  2DZY A;  5FPW A;  3OVZ A;  3F75 A;  3LFY A;  3O1G A;  3WXG A;  3BOW A;  4PI3 A;  3IMA A;  4PP2 E;  2G8J A;  2XU5 A;  3TNX A;  1PCI A;  2DC8 A;  3N3K A;  4OEM A;  3RVW A;  1AEC A;  1AU4 A;  1F29 A;  3D6S A;  1F2A A;  2CB5 A;  1AU3 A;  4RY2 A;  3HWN A;  4YYV A;  2DCD A;  4YYQ A;  3BCN A;  4YYR A;  4BQV A;  4I04 A;  3KWZ A;  1BGO A;  1EWL A;  1ICF A;  4K7C A;  1EWM A;  2Y5B A;  2HXZ A;  3OF9 A;  3MHS A;  2YJ9 A;  3H6S A;  5JH3 A;  4PP1 A;  3BWK A;  4QBB A;  1MIR A;  2AIM A;  5CVO B;  1EF7 A;  2AVW A;  1DEU A;  3KSE A;  1NL6 A;  3RVV A;  2AS8 A;  4FK5 A;  1CS8 A;  3E1Z B;  1O0E A;  1NPZ A;  2FTD A;  1AYU A;  3PBH A;  4BS5 A;  1KHP A;  1KXR A;  4YYU A;  1XKG A;  3P5W A;  1YK7 A;  4I07 A;  2PBH A;  3OVX A;  1U9V A;  2DC6 A;  3MOR A;  4FIP A;  3V6C A;  1A6R A;  4W4U A;  2XU3 A;  2R9C A;  1IWD A;  4I05 A;  3P5U A;  2GHU A;  1EWP A;  2VHF A;  1FH0 A;  4DMY A;  3BPM A;  1TLO A;  3H89 A;  2ARY A;  2DC9 A;  1NLJ A;  1NB5 A;  2R6N A;  1JQP A;  3M99 A;  3QT4 A;  2NQD B;  1CSB B;  4P6G A;  1F2C A;  3RVX A;  4YV8 A;  2E01 A;  3KW9 A;  2E02 A;  5JA7 A;  4Q8H A;  3H8B A;  1PAD A;  3HHI A;  4BSQ A;  4QRV A;  1MS6 A;  2ATO A;  1M6D A;  3S3R A;  1YAL A;  4X6H A;  2IPP B;  4P6E A;  1ITO A;  1CQD A;  1GCB A;  3HHA A;  6PAD A;  4YYS A;  1F2B A;  2DJF B;  3U8E A;  4AXL A;  2HH5 A;  1BP4 A;  3BPF A;  4YYW A;  1S4V A; 
#chains in the Genus database with same CATH topology
 2OUL A;  1Q6K A;  2DOS A;  2JTC A;  3OQC A;  3W30 A;  3ERV A;  3H7D A;  3RNV A;  3IEJ A;  3K8U A;  3QSD A;  1TL9 A;  4AXM A;  3W31 A;  2PNS A;  2AU1 A;  3BC3 A;  2E03 A;  2DJG B;  2HHN A;  3MHH A;  2B1N A;  3MP2 A;  2G7Y A;  1MEM A;  2ACT A;  5KO3 A;  2E00 A;  2DCC A;  2HD5 A;  4N8W A;  3S3Q A;  3IV2 A;  4BOS A;  1MEG A;  1U5I A;  1Y08 A;  2FQ9 A;  5EF4 A;  5F02 A;  4BS6 A;  3QJ3 A;  5K16 A;  3E9S A;  3V6E A;  4CZW A;  1MDW A;  2R9F A;  2DC7 A;  4CDF B;  3IHP A;  3P5X A;  7PCK A;  5EGW A;  4N79 A;  3AI8 A;  4OEL A;  3PW3 A;  1U9X A;  3PDF A;  2Y6E A;  1QMY A;  3LXS A;  4PT5 A;  1MHW A;  4D8B A;  4MZS A;  5PAD A;  2YJ8 A;  3K9M A;  4CDD B;  4X6J A;  2G6D A;  1POP A;  1BQI A;  1SNK A;  2XU1 A;  1GLO A;  4N4Z A;  3OF8 A;  3CBJ A;  1CPJ A;  1YVB A;  1GMY A;  3F5V A;  2FT2 A;  1PPN A;  2FYE A;  9PAP A;  1STF E;  3WXF A;  4KLB A;  1CVZ A;  1TU6 A;  2FRQ A;  3MTN A;  2VHS A;  3N4C A;  3DF0 A;  1UKF A;  1AYW A;  2CIO A;  1NB3 A;  8PCH A;  4MI7 A;  1ZIV A;  4XUI A;  2PRE A;  1QXP A;  1PPP A;  5A24 A;  2O6X A;  4HXD B;  1CJL A;  2F1G A;  1ME3 A;  3B79 A;  4GUA A;  1KHQ A;  1AU0 A;  2R9O A;  3HD3 A;  3CH3 X;  2C0Y A;  3IUT A;  4W5C A;  1ME4 A;  5CVM A;  1QOL A;  3NHE A;  5J94 A;  2Z84 A;  1AIM A;  5JZE A;  2IBI A;  2HWK A;  1AYV A;  3CH2 X;  5CVN B;  1QDQ A;  2DZZ A;  5EZS A;  2WBF X;  3KFQ A;  4DMX A;  2GFO A;  3BBA A;  1KFX L;  2AYO A;  2P0R A;  2BDZ A;  1YT7 A;  2G8E A;  2PAD A;  4IUM A;  2JQF R;  3OIS A;  1Y4H A;  3I06 A;  4REZ A;  2DCA A;  3N3G A;  3P5V A;  4CDC B;  1U9W A;  1PBH A;  4ZTB A;  3TMP A;  1PPD A;  1GEC E;  1AU2 A;  3O0U A;  2F7D A;  4QRG A;  4ZUX U;  4FJC A;  1PVJ A;  1YK8 A;  4QRX A;  1CB5 A;  2UZJ A;  2AGA A;  4YVA A;  2BDL A;  3C9E A;  1NQC A;  3PNR A;  2JQG R;  2FO5 A;  2R9M A;  1BY8 A;  4X6I A;  1K3B B;  4G54 A;  3PHW A;  1DF0 A;  2OP3 A;  4MSX A;  2P7U A;  3WXE A;  1PPO A;  2YJC A;  2H7J A;  1U9Q X;  2YJ2 A;  1PXV A;  4HWY A;  4MZO A;  2XU4 A;  1VJV A;  1SP4 B;  4BOU A;  4P16 A;  4Q8G A;  4RKX A;  2R9N A;  4M0W A;  1PIP A;  2FRA A;  4WA6 A;  3KWB X;  1THE A;  2NQI A;  2P86 A;  1X9Y A;  2B1M A;  4PAD A;  3TRK A;  1KFU L;  2AUX A;  1YZB A;  2YJB A;  2DCB A;  1VSN A;  3H8C A;  3ZUA A;  4W5B A;  3GCB A;  4RF0 A;  1ATK A;  1EWO A;  4QH6 A;  1CV8 A;  3CBK A;  3KKU A;  1PE6 A;  3KX1 A;  4XR7 A;  3IOQ A;  4BPV A;  3C0R A;  2AUZ A;  2AYN A;  2NQA A;  1HUC B;  1ZCM A;  5CHV A;  3USV A;  4D8I A;  1CTE A;  2OZ2 A;  3K24 A;  5CHT A;  2NQG A;  3PSE A;  3I3T A;  2FUD A;  4CDE B;  2DZY A;  4BOZ A;  1DKI A;  5FPW A;  3OVZ A;  3F75 A;  3LFY A;  3O1G A;  3WXG A;  3BOW A;  4PI3 A;  3IMA A;  4PP2 E;  2G8J A;  2XU5 A;  3TNX A;  1PCI A;  2DC8 A;  3N3K A;  4BOQ A;  4OEM A;  3RVW A;  1AEC A;  1AU4 A;  2J7Q A;  1F29 A;  3D6S A;  1F2A A;  2CB5 A;  1AU3 A;  4RY2 A;  3HWN A;  4RF1 A;  4YYV A;  2DCD A;  4YYQ A;  3BCN A;  4YYR A;  4BQV A;  4I04 A;  3KWZ A;  3PHU A;  1BGO A;  1EWL A;  3ZNH A;  1ICF A;  4K7C A;  1EWM A;  2Y5B A;  2FE8 A;  2HXZ A;  3OF9 A;  3MHS A;  2YJ9 A;  3H6S A;  4XZX A;  5JH3 A;  4PP1 A;  3BWK A;  4QBB A;  3IFU A;  1MIR A;  2AIM A;  4BOP A;  5CVO B;  1EF7 A;  2AVW A;  1DEU A;  3KSE A;  3BY4 A;  1NL6 A;  3RVV A;  2AS8 A;  4FK5 A;  1CS8 A;  3E1Z B;  1O0E A;  5E6J A;  1NPZ A;  2FTD A;  1AYU A;  3PBH A;  4BS5 A;  1KHP A;  1KXR A;  4YYU A;  1XKG A;  3PHX A;  3PRM A;  2BTW A;  3P5W A;  1YK7 A;  4I07 A;  2PBH A;  4R3D A;  3OVX A;  1U9V A;  2DC6 A;  3MOR A;  4FIP A;  3V6C A;  1A6R A;  4W4U A;  2XU3 A;  2R9C A;  3B21 A;  1IWD A;  3PT2 A;  2BTW B;  4I05 A;  3P5U A;  2GHU A;  1EWP A;  2VHF A;  1FH0 A;  4DMY A;  3BPM A;  3MTV A;  1TLO A;  3H89 A;  2ARY A;  3PRP A;  2J7Q C;  2DC9 A;  1NLJ A;  4MM3 B;  1NB5 A;  2R6N A;  1JQP A;  3M99 A;  2BU3 A;  3QT4 A;  4OW0 A;  2NQD B;  4OVZ A;  5EZQ A;  3O65 A;  1CSB B;  4P6G A;  1F2C A;  3RVX A;  4YV8 A;  3MJ5 A;  2E01 A;  3KW9 A;  2E02 A;  5JA7 A;  4OVZ B;  4A5U A;  2JRI A;  4IP3 A;  4Q8H A;  3H8B A;  1PAD A;  3HHI A;  4BSQ A;  4D8E A;  4QRV A;  1MS6 A;  2ATO A;  3BB7 A;  1M6D A;  3S3R A;  1YAL A;  4WUR A;  4X6H A;  2IPP B;  4P6E A;  1ITO A;  1CQD A;  1GCB A;  3HHA A;  6PAD A;  4YYS A;  1F2B A;  2DJF B;  3U8E A;  4RNA A;  4AXL A;  2HH5 A;  1BP4 A;  3BPF A;  4YYW A;  1S4V A; 
#chains in the Genus database with same CATH homology
 2OUL A;  1Q6K A;  4B55 A;  3ERV A;  3H7D A;  3IEJ A;  3K8U A;  3QSD A;  3LTW A;  1TL9 A;  4AXM A;  2PNS A;  2AU1 A;  3BC3 A;  2E03 A;  2DJG B;  2HHN A;  3MHH A;  2B1N A;  4NV7 A;  2G7Y A;  1MEM A;  2ACT A;  2E00 A;  2DCC A;  2VFB A;  2HD5 A;  4N8W A;  3S3Q A;  3IV2 A;  1MEG A;  1U5I A;  1Y08 A;  2FQ9 A;  5EF4 A;  5F02 A;  4BS6 A;  3QJ3 A;  5K16 A;  3V6E A;  4CZW A;  1MDW A;  1W6F A;  2R9F A;  2DC7 A;  4CDF B;  3IHP A;  3P5X A;  7PCK A;  5EGW A;  4N79 A;  3AI8 A;  4OEL A;  3PW3 A;  1U9X A;  3PDF A;  2Y6E A;  1QMY A;  3LXS A;  1MHW A;  4MZS A;  5PAD A;  2YJ8 A;  3K9M A;  4CDD B;  4X6J A;  2G6D A;  1POP A;  1BQI A;  1SNK A;  2XU1 A;  1GLO A;  4N4Z A;  3OF8 A;  3CBJ A;  1CPJ A;  1YVB A;  1GMY A;  3F5V A;  2FT2 A;  1PPN A;  2FYE A;  9PAP A;  1STF E;  3WXF A;  4KLB A;  1CVZ A;  1TU6 A;  2FRQ A;  3MTN A;  2VHS A;  3N4C A;  3DF0 A;  1AYW A;  2CIO A;  1NB3 A;  8PCH A;  1ZIV A;  4XUI A;  2PRE A;  1QXP A;  1PPP A;  4NV8 A;  5A24 A;  2O6X A;  1CJL A;  2F1G A;  1ME3 A;  3B79 A;  1KHQ A;  1AU0 A;  2R9O A;  3HD3 A;  3CH3 X;  2C0Y A;  3IUT A;  4W5C A;  1ME4 A;  5CVM A;  1QOL A;  3NHE A;  5J94 A;  2BSZ A;  1AIM A;  2IBI A;  1AYV A;  3CH2 X;  5CVN B;  1QDQ A;  2DZZ A;  2WBF X;  3KFQ A;  4DMX A;  2GFO A;  1KFX L;  2AYO A;  2P0R A;  2BDZ A;  1YT7 A;  2G8E A;  2PAD A;  2JQF R;  3OIS A;  1Y4H A;  3I06 A;  2DCA A;  3N3G A;  3P5V A;  4CDC B;  1U9W A;  1PBH A;  1PPD A;  1GEC E;  1AU2 A;  3O0U A;  2F7D A;  4QRG A;  4ZUX U;  4FJC A;  1YK8 A;  1E2T A;  4QRX A;  1CB5 A;  4YVA A;  2BDL A;  3C9E A;  1NQC A;  1W4T A;  3PNR A;  2JQG R;  2FO5 A;  2R9M A;  1BY8 A;  4X6I A;  1K3B B;  4G54 A;  1DF0 A;  2OP3 A;  4MSX A;  2P7U A;  3WXE A;  1PPO A;  2YJC A;  2H7J A;  1U9Q X;  2YJ2 A;  1PXV A;  4HWY A;  4MZO A;  2XU4 A;  1VJV A;  1SP4 B;  4Q8G A;  2R9N A;  1PIP A;  2FRA A;  4WA6 A;  3KWB X;  1THE A;  2NQI A;  2P86 A;  1X9Y A;  2B1M A;  4PAD A;  1KFU L;  2AUX A;  2YJB A;  2DCB A;  1VSN A;  3H8C A;  3ZUA A;  4W5B A;  3GCB A;  1ATK A;  1EWO A;  4QH6 A;  1CV8 A;  3CBK A;  3KKU A;  1PE6 A;  3KX1 A;  4XR7 A;  3IOQ A;  4BPV A;  2AUZ A;  2AYN A;  2NQA A;  1HUC B;  1ZCM A;  5CHV A;  3USV A;  1CTE A;  2OZ2 A;  3K24 A;  5CHT A;  2NQG A;  3I3T A;  2FUD A;  4CDE B;  2DZY A;  5FPW A;  3OVZ A;  3F75 A;  4BGF A;  3LFY A;  3O1G A;  3WXG A;  3BOW A;  4PI3 A;  3IMA A;  4PP2 E;  2G8J A;  2XU5 A;  3TNX A;  1PCI A;  2DC8 A;  3N3K A;  3D9W A;  4OEM A;  3RVW A;  1AEC A;  1AU4 A;  1F29 A;  3D6S A;  1F2A A;  2CB5 A;  1AU3 A;  4RY2 A;  3HWN A;  4YYV A;  4C5P A;  2DCD A;  4YYQ A;  3BCN A;  4YYR A;  4BQV A;  4I04 A;  3KWZ A;  1BGO A;  1EWL A;  1ICF A;  4K7C A;  1EWM A;  2Y5B A;  2HXZ A;  3OF9 A;  3MHS A;  2YJ9 A;  3H6S A;  5JH3 A;  4PP1 A;  3BWK A;  4QBB A;  1MIR A;  2AIM A;  5CVO B;  1EF7 A;  2AVW A;  1DEU A;  3KSE A;  1NL6 A;  3RVV A;  2AS8 A;  4FK5 A;  1CS8 A;  3E1Z B;  1O0E A;  1NPZ A;  2FTD A;  1AYU A;  3PBH A;  4BS5 A;  1KHP A;  2VFC A;  1KXR A;  4YYU A;  1XKG A;  3P5W A;  1YK7 A;  4I07 A;  2PBH A;  3OVX A;  1U9V A;  2DC6 A;  3MOR A;  4FIP A;  3V6C A;  1A6R A;  4W4U A;  2XU3 A;  2R9C A;  1IWD A;  4I05 A;  3P5U A;  2GHU A;  1EWP A;  2VHF A;  1FH0 A;  4DMY A;  3BPM A;  1TLO A;  3H89 A;  2ARY A;  2DC9 A;  1NLJ A;  1NB5 A;  2R6N A;  1JQP A;  3M99 A;  3QT4 A;  2NQD B;  1CSB B;  4P6G A;  1F2C A;  3RVX A;  4YV8 A;  2E01 A;  3KW9 A;  2E02 A;  5JA7 A;  4Q8H A;  3H8B A;  1PAD A;  3HHI A;  4BSQ A;  4QRV A;  1MS6 A;  2ATO A;  1M6D A;  3S3R A;  1YAL A;  4X6H A;  2IPP B;  4P6E A;  1ITO A;  1CQD A;  1GCB A;  3HHA A;  6PAD A;  1W5R A;  4YYS A;  1F2B A;  2DJF B;  3U8E A;  4AXL A;  2HH5 A;  4GUZ A;  1BP4 A;  3BPF A;  1GX3 A;  4YYW A;  1S4V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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