1TL9A

High resolution crystal structure of calpain i protease core in complex with leupeptin
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
321
structure length
321
Chain Sequence
NAIKYLGQDYENLRARCLQNGVLFQDDAFPPVSHSLGFKELGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNETILHRVVPYGQSFQEGYAGIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHSAQGNEFWSALLEKAYAKVNGSYEALSGGCTSEAFEDFTGGVTEWYDLQKAPSDLYQIILKALERGSLLGCSINISDIRDLEAITFKNLVRGHAYSVTDAKQVTYQGQRVNLIRMRNPWGEVEWKGPWSDNSYEWNKVDPYEREQLRVKMEDGEFWMSFRDFIREFTKLEICNL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Calpain 1, large [catalytic] subunit
publication title Crystal Structures of Calpain-E64 and -Leupeptin Inhibitor Complexes Reveal Mobile Loops Gating the Active Site
pubmed doi rcsb
source organism Rattus norvegicus
molecule tags Hydrolase/hydrolase inhibitor
total genus 96
structure length 321
sequence length 321
ec nomenclature ec 3.4.22.52: Calpain-1.
pdb deposition date 2004-06-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00648 Peptidase_C2 Calpain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1tl9A02
1GLOA 2DCCA 1YALA 4Q8HA 3OVZA 4FJCA 1Y08A 3ZUAA 3HWNA 3BCNA 4N4ZA 3BOWA 4AXLA 1VJVA 3B79A 1MHWA 1CS8A 1THEA 1AYUA 1F2BA 4N79A 2G7YA 1JQPA 3KW9A 2DCDA 1GCBA 4OEMA 2AS8A 2F7DA 3LXSA 1SP4B 3PBHA 3RVVA 4FK5A 1AIMA 3TNXA 3BPFA 1Q6KA 3IV2A 2R9OA 3HD3A 1QMYA 3P5VA 4YYUA 3HHIA 2PNSA 3WXFA 5JH3A 4QRXA 2FT2A 2BDZA 4YYRA 1NLJA 1F2AA 3BWKA 3H6SA 2DC8A 2F1GA 3MTNA 4MSXA 3H8BA 2G8JA 3BPMA 4PI3A 1MEGA 4CDCB 4DMXA 3KWZA 1KHPA 5K16A 2FRAA 2AYNA 2E00A 1NQCA 1STFE 3IMAA 1EWMA 1U5IA 2AIMA 1KHQA 2P0RA 1PPDA 2FQ9A 2Y5BA 2ACTA 3HHAA 4YV8A 5F02A 4PADA 1ZIVA 3CBKA 2R6NA 1MS6A 2XU3A 2AYOA 1A6RA 4FIPA 5CHVA 4BPVA 3KSEA 3OVXA 1AECA 4YVAA 4CZWA 1HUCB 2VHSA 2XU5A 1GECE 2JQFR 2DC7A 2DZZA 1BGOA 4N8WA 3N4CA 3K24A 2P7UA 3P5WA 4MZSA 3S3RA 4DMYA 1M6DA 2O6XA 3OF9A 4BSQA 4BS6A 3IEJA 1Y4HA 3NHEA 4YYWA 1U9WA 3V6CA 2CB5A 5CVNB 4G54A 2YJ2A 2HXZA 3I3TA 3MHSA 1VSNA 1AU3A 1NL6A 1U9XA 2B1MA 2DJFB 3DF0A 2AU1A 2DC9A 1PXVA 4HWYA 5FPWA 3CH2X 1FH0A 3CBJA 2PBHA 4CDDB 3N3KA 1XKGA 3S3QA 1O0EA 2FTDA 2AVWA 2VHFA 2NQIA 1X9YA 2P86A 1EWOA 2E01A 1ICFA 3N3GA 2OULA 2AUXA 4YYQA 4X6JA 1KFXL 1QOLA 2YJBA 1F29A 3WXGA 2YJ9A 3MORA 1BY8A 1ME4A 4PP1A 3RVXA 4W5CA 3M99A 4KLBA 3E1ZB 1CPJA 3H89A 1EWPA 1S4VA 2NQAA 1AU2A 2OZ2A 3LFYA 4PP2E 1GMYA 3CH3X 1MEMA 2PREA 1KFUL 2NQGA 3ERVA 3KX1A 1U9VA 5J94A 2FYEA 3IUTA 2HH5A 3OISA 4CDFB 3C9EA 2R9MA 3USVA 4XR7A 2XU4A 5PADA 1YK7A 4Q8GA 1IWDA 4QRVA 1CTEA 3QT4A 3MHHA 2AUZA 1PPPA 1NB3A 4X6IA 1K3BB 3OF8A 4YYVA 1TU6A 4P6EA 4P6GA 1AU0A 3H7DA 3D6SA 4X6HA 2HHNA 2GFOA 4W5BA 1CB5A 3PNRA 4I04A 2GHUA 2R9CA 1YK8A 2ATOA 2G6DA 2CIOA 3KFQA 1NPZA 3I06A 4QBBA 4WA6A 4W4UA 1U9QX 3P5UA 1CJLA 3KKUA 2HD5A 2R9FA 2E02A 5A24A 2PADA 2YJ8A 2G8EA 3O0UA 2B1NA 2YJCA 2R9NA 1TL9A 1MIRA 2E03A 1YT7A 1BQIA 3IOQA 1CQDA 3QSDA 4XUIA 2NQDB 1ME3A 3PW3A 9PAPA 2OP3A 2DCAA 2ARYA 1PBHA 1SNKA 3AI8A 3RVWA 1AYVA 2DCBA 1TLOA 3IHPA 2DZYA 2FRQA 2IPPB 1PPOA 5EF4A 3K9MA 4OELA 1F2CA 2C0YA 4YYSA 2WBFX 3KWBX 3BC3A 3PDFA 2Y6EA 3V6EA 1ATKA 3GCBA 2FO5A 1NB5A 4I07A 1PIPA 1PPNA 2DC6A 1BP4A 1CSBB 1POPA 1YVBA 5JA7A 3H8CA 1EF7A 1EWLA 4I05A 1PCIA 2DJGB 1KXRA 3WXEA 1PE6A 4BS5A 1AYWA 3P5XA 4QRGA 2XU1A 1AU4A 1DF0A 1PADA 1MDWA 3F75A 4RY2A 3QJ3A 5CVMA 3U8EA 2BDLA 5EGWA 3F5VA 6PADA 8PCHA 3K8UA 2H7JA 2IBIA 1CV8A 1ZCMA 1QDQA 1DEUA 4K7CA 4MZOA 5CHTA 1ITOA 2JQGR 1CVZA 4BQVA 4AXMA 5CVOB 2FUDA 4QH6A 4ZUXU 7PCKA 4CDEB 3O1GA 1QXPA
chains in the Genus database with same CATH superfamily
1GLOA 3PRPA 2DCCA 1YALA 4Q8HA 3OVZA 4FJCA 1Y08A 3ZUAA 3HWNA 3BCNA 4N4ZA 3BOWA 4AXLA 1VJVA 3B79A 1MHWA 1CS8A 1THEA 1AYUA 4IUMA 4D8IA 1F2BA 4N79A 2G7YA 1UKFA 1JQPA 3KW9A 2DCDA 1GCBA 4OEMA 2AS8A 2F7DA 3LXSA 1SP4B 3PBHA 4BOQA 3RVVA 4FK5A 1AIMA 3TNXA 3BPFA 1Q6KA 3IV2A 2R9OA 3HD3A 1QMYA 3P5VA 4YYUA 3HHIA 2HWKA 2PNSA 3WXFA 5JH3A 4QRXA 2FT2A 4HXDB 3B21A 2BDZA 4YYRA 1NLJA 1F2AA 3BWKA 3H6SA 2JRIA 2DC8A 2F1GA 4R3DA 3MTNA 4MSXA 3H8BA 2G8JA 3BPMA 4PI3A 1MEGA 4CDCB 4DMXA 3KWZA 1KHPA 5K16A 2FRAA 2AYNA 2E00A 1NQCA 1STFE 3IMAA 1EWMA 2BU3A 1U5IA 2AIMA 1KHQA 2P0RA 1PPDA 2FQ9A 2Y5BA 4RF0A 2ACTA 3HHAA 4YV8A 5F02A 4PADA 1ZIVA 3CBKA 2R6NA 1MS6A 2XU3A 2AYOA 1A6RA 4FIPA 5CHVA 4BPVA 3KSEA 3OVXA 3PRMA 4OVZB 1AECA 4YVAA 3PT2A 4CZWA 1PVJA 5EZQA 1HUCB 2VHSA 2XU5A 1GECE 3TRKA 2JQFR 2DC7A 2DZZA 1BGOA 3BB7A 3N4CA 4N8WA 3K24A 2P7UA 3P5WA 4MZSA 3S3RA 4DMYA 2FE8A 2JTCA 1M6DA 4M0WA 2O6XA 3OF9A 3IFUA 3PHUA 3PHWA 3W31A 4BSQA 4BS6A 3MTVA 2UZJA 3IEJA 1Y4HA 3NHEA 4YYWA 3W30A 1U9WA 3V6CA 2CB5A 5CVNB 4G54A 2YJ2A 2HXZA 3I3TA 3MHSA 4BOUA 1VSNA 1AU3A 1NL6A 1U9XA 2B1MA 4ZTBA 2DJFB 3DF0A 2AU1A 4BOSA 2DC9A 1PXVA 4HWYA 5FPWA 3CH2X 1FH0A 3CBJA 2J7QC 2PBHA 4CDDB 3N3KA 1XKGA 2Z84A 3S3QA 1O0EA 2FTDA 2AVWA 3C0RA 2VHFA 2NQIA 1X9YA 2P86A 1EWOA 2E01A 1ICFA 3N3GA 4MM3B 3TMPA 2OULA 2AUXA 3MP2A 4YYQA 4X6JA 1KFXL 4XZXA 1QOLA 2YJBA 1F29A 3WXGA 2YJ9A 3MORA 1BY8A 1ME4A 4PP1A 3RVXA 4W5CA 3M99A 4KLBA 3E1ZB 1CPJA 3H89A 1EWPA 1S4VA 2NQAA 1AU2A 2OZ2A 3ZNHA 3LFYA 4PP2E 1GMYA 3CH3X 1MEMA 3O65A 2PREA 1KFUL 2NQGA 3ERVA 3KX1A 1U9VA 5J94A 2FYEA 3IUTA 2HH5A 4RNAA 3OISA 4CDFB 3C9EA 4OW0A 2R9MA 3USVA 4P16A 2J7QA 3MJ5A 4XR7A 2XU4A 4PT5A 5PADA 1YK7A 4Q8GA 1IWDA 4QRVA 1CTEA 1DKIA 3QT4A 3MHHA 2AUZA 1PPPA 1NB3A 4X6IA 1K3BB 2BTWA 3OF8A 4YYVA 1TU6A 4P6EA 4P6GA 5KO3A 1AU0A 3H7DA 3D6SA 4X6HA 2HHNA 3OQCA 2GFOA 4W5BA 5E6JA 1CB5A 3PNRA 4I04A 2GHUA 2R9CA 4D8EA 1YK8A 2ATOA 2G6DA 2CIOA 3KFQA 1NPZA 3I06A 4QBBA 4WA6A 4W4UA 1U9QX 3P5UA 1CJLA 3KKUA 1YZBA 2HD5A 2R9FA 2E02A 5A24A 4GUAA 2PADA 2YJ8A 2G8EA 3O0UA 2B1NA 2YJCA 2R9NA 5EZSA 1TL9A 1MIRA 2E03A 1YT7A 1BQIA 3IOQA 1CQDA 3QSDA 4XUIA 2NQDB 1ME3A 3PW3A 9PAPA 2OP3A 2DCAA 2ARYA 1PBHA 1SNKA 3AI8A 3RVWA 1AYVA 5JZEA 2DCBA 1TLOA 3IHPA 2DZYA 2FRQA 2IPPB 1PPOA 5EF4A 3K9MA 4OELA 1F2CA 2C0YA 4YYSA 2WBFX 3KWBX 4IP3A 3BC3A 3PDFA 2Y6EA 4RF1A 3V6EA 1ATKA 3GCBA 2FO5A 1NB5A 4I07A 4REZA 1PIPA 1PPNA 2DC6A 4D8BA 3E9SA 1BP4A 3BY4A 1CSBB 1POPA 1YVBA 5JA7A 3H8CA 1EF7A 1EWLA 4I05A 1PCIA 2DJGB 1KXRA 3WXEA 3PHXA 1PE6A 4BS5A 1AYWA 3P5XA 4MI7A 4QRGA 2XU1A 3PSEA 1AU4A 1DF0A 1PADA 1MDWA 4BOZA 3F75A 4RY2A 3BBAA 3QJ3A 5CVMA 3U8EA 2BDLA 3RNVA 5EGWA 3F5VA 2AGAA 6PADA 8PCHA 3K8UA 2DOSA 2H7JA 2IBIA 4OVZA 1CV8A 1ZCMA 1QDQA 4BOPA 1DEUA 4K7CA 4MZOA 5CHTA 1ITOA 2JQGR 1CVZA 4BQVA 2BTWB 4AXMA 5CVOB 2FUDA 4RKXA 4QH6A 4A5UA 4WURA 4ZUXU 7PCKA 4CDEB 3O1GA 1QXPA
chains in the Genus database with same CATH topology
1GLOA 4GUZA 2DCCA 1YALA 4Q8HA 3OVZA 4FJCA 1Y08A 3ZUAA 3HWNA 3BCNA 4N4ZA 3BOWA 4AXLA 1VJVA 3B79A 1MHWA 1CS8A 1THEA 1AYUA 1W5RA 1F2BA 4N79A 2G7YA 1JQPA 3KW9A 2DCDA 1GCBA 4OEMA 2AS8A 2F7DA 3LXSA 1SP4B 3PBHA 3RVVA 4FK5A 1AIMA 3TNXA 3BPFA 1Q6KA 3IV2A 2R9OA 3HD3A 1QMYA 4NV7A 3P5VA 4YYUA 3HHIA 2PNSA 3WXFA 5JH3A 4QRXA 2FT2A 2BDZA 4YYRA 1NLJA 1F2AA 3BWKA 3H6SA 2DC8A 2F1GA 3MTNA 4MSXA 3H8BA 2G8JA 3BPMA 4PI3A 1MEGA 4CDCB 4DMXA 3KWZA 1KHPA 5K16A 2FRAA 2AYNA 2E00A 1NQCA 1STFE 3IMAA 1EWMA 1U5IA 2AIMA 1KHQA 2P0RA 1PPDA 2FQ9A 2Y5BA 2ACTA 3HHAA 4YV8A 5F02A 4PADA 2VFBA 1ZIVA 3CBKA 2R6NA 1MS6A 2XU3A 2AYOA 1A6RA 4FIPA 5CHVA 4BPVA 3KSEA 3OVXA 1AECA 4YVAA 4CZWA 1HUCB 2VHSA 2XU5A 1GECE 2JQFR 2DC7A 2DZZA 1BGOA 4N8WA 3N4CA 3K24A 2P7UA 3P5WA 4MZSA 3S3RA 4DMYA 1M6DA 2O6XA 3OF9A 4BSQA 4BS6A 3IEJA 1Y4HA 3NHEA 4YYWA 1U9WA 3V6CA 2CB5A 5CVNB 4G54A 2YJ2A 2HXZA 3I3TA 3MHSA 1VSNA 1AU3A 1NL6A 1U9XA 2B1MA 1W6FA 2DJFB 3DF0A 2AU1A 2DC9A 1PXVA 4HWYA 5FPWA 3CH2X 1FH0A 3CBJA 2PBHA 4CDDB 3N3KA 1XKGA 3S3QA 1O0EA 2FTDA 2AVWA 2VHFA 2NQIA 1X9YA 2P86A 1EWOA 2E01A 1ICFA 3N3GA 2OULA 2AUXA 4YYQA 4X6JA 1KFXL 4BGFA 1QOLA 2YJBA 1F29A 3WXGA 2YJ9A 3MORA 1BY8A 1ME4A 4PP1A 3RVXA 4W5CA 3M99A 4KLBA 3LTWA 3E1ZB 1CPJA 3H89A 1EWPA 1S4VA 2NQAA 1AU2A 2OZ2A 3LFYA 4PP2E 1GMYA 3CH3X 1MEMA 2PREA 1KFUL 2NQGA 3ERVA 3KX1A 1U9VA 5J94A 2FYEA 3IUTA 2HH5A 3OISA 4CDFB 4NV8A 3C9EA 2R9MA 3USVA 4XR7A 2XU4A 5PADA 1YK7A 4Q8GA 1IWDA 4QRVA 1CTEA 3QT4A 3MHHA 2AUZA 1PPPA 1NB3A 4X6IA 1K3BB 3OF8A 4YYVA 1TU6A 4P6EA 4P6GA 1AU0A 3H7DA 3D6SA 4X6HA 2HHNA 2GFOA 4W5BA 2BSZA 1CB5A 3PNRA 4I04A 2GHUA 2R9CA 1YK8A 2ATOA 2G6DA 2CIOA 3KFQA 1NPZA 3I06A 4QBBA 1GX3A 4WA6A 4W4UA 1U9QX 3P5UA 1CJLA 3KKUA 2HD5A 2R9FA 2E02A 5A24A 2PADA 2YJ8A 2G8EA 3O0UA 2B1NA 2YJCA 2R9NA 1TL9A 1MIRA 2E03A 1YT7A 1BQIA 3IOQA 1CQDA 3QSDA 4XUIA 2NQDB 1ME3A 3PW3A 9PAPA 2OP3A 2DCAA 2ARYA 1PBHA 1SNKA 3AI8A 2VFCA 3RVWA 1AYVA 2DCBA 1TLOA 4C5PA 3IHPA 2DZYA 2FRQA 2IPPB 1PPOA 5EF4A 3K9MA 4OELA 1F2CA 2C0YA 4YYSA 2WBFX 3KWBX 3BC3A 3PDFA 2Y6EA 3V6EA 1ATKA 3GCBA 2FO5A 1NB5A 4I07A 1PIPA 1PPNA 2DC6A 1BP4A 1CSBB 1POPA 1YVBA 5JA7A 3H8CA 1EF7A 1EWLA 4I05A 1PCIA 1W4TA 2DJGB 1KXRA 3WXEA 1PE6A 4BS5A 1AYWA 3P5XA 4QRGA 2XU1A 1AU4A 1DF0A 1PADA 1MDWA 1E2TA 3F75A 3D9WA 4RY2A 3QJ3A 5CVMA 3U8EA 2BDLA 5EGWA 3F5VA 6PADA 8PCHA 3K8UA 2H7JA 2IBIA 1CV8A 1ZCMA 1QDQA 1DEUA 4K7CA 4MZOA 5CHTA 1ITOA 2JQGR 1CVZA 4BQVA 4AXMA 5CVOB 2FUDA 4QH6A 4ZUXU 4B55A 7PCKA 4CDEB 3O1GA 1QXPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GLO A;  2DCC A;  1YAL A;  4Q8H A;  3OVZ A;  4FJC A;  1Y08 A;  3ZUA A;  3HWN A;  3BCN A;  4N4Z A;  3BOW A;  4AXL A;  1VJV A;  3B79 A;  1MHW A;  1CS8 A;  1THE A;  1AYU A;  1F2B A;  4N79 A;  2G7Y A;  1JQP A;  3KW9 A;  2DCD A;  1GCB A;  4OEM A;  2AS8 A;  2F7D A;  3LXS A;  1SP4 B;  3PBH A;  3RVV A;  4FK5 A;  1AIM A;  3TNX A;  3BPF A;  1Q6K A;  3IV2 A;  2R9O A;  3HD3 A;  1QMY A;  3P5V A;  4YYU A;  3HHI A;  2PNS A;  3WXF A;  5JH3 A;  4QRX A;  2FT2 A;  2BDZ A;  4YYR A;  1NLJ A;  1F2A A;  3BWK A;  3H6S A;  2DC8 A;  2F1G A;  3MTN A;  4MSX A;  3H8B A;  2G8J A;  3BPM A;  4PI3 A;  1MEG A;  4CDC B;  4DMX A;  3KWZ A;  1KHP A;  5K16 A;  2FRA A;  2AYN A;  2E00 A;  1NQC A;  1STF E;  3IMA A;  1EWM A;  1U5I A;  2AIM A;  1KHQ A;  2P0R A;  1PPD A;  2FQ9 A;  2Y5B A;  2ACT A;  3HHA A;  4YV8 A;  5F02 A;  4PAD A;  1ZIV A;  3CBK A;  2R6N A;  1MS6 A;  2XU3 A;  2AYO A;  1A6R A;  4FIP A;  5CHV A;  4BPV A;  3KSE A;  3OVX A;  1AEC A;  4YVA A;  4CZW A;  1HUC B;  2VHS A;  2XU5 A;  1GEC E;  2JQF R;  2DC7 A;  2DZZ A;  1BGO A;  4N8W A;  3N4C A;  3K24 A;  2P7U A;  3P5W A;  4MZS A;  3S3R A;  4DMY A;  1M6D A;  2O6X A;  3OF9 A;  4BSQ A;  4BS6 A;  3IEJ A;  1Y4H A;  3NHE A;  4YYW A;  1U9W A;  3V6C A;  2CB5 A;  5CVN B;  4G54 A;  2YJ2 A;  2HXZ A;  3I3T A;  3MHS A;  1VSN A;  1AU3 A;  1NL6 A;  1U9X A;  2B1M A;  2DJF B;  3DF0 A;  2AU1 A;  2DC9 A;  1PXV A;  4HWY A;  5FPW A;  3CH2 X;  1FH0 A;  3CBJ A;  2PBH A;  4CDD B;  3N3K A;  1XKG A;  3S3Q A;  1O0E A;  2FTD A;  2AVW A;  2VHF A;  2NQI A;  1X9Y A;  2P86 A;  1EWO A;  2E01 A;  1ICF A;  3N3G A;  2OUL A;  2AUX A;  4YYQ A;  4X6J A;  1KFX L;  1QOL A;  2YJB A;  1F29 A;  3WXG A;  2YJ9 A;  3MOR A;  1BY8 A;  1ME4 A;  4PP1 A;  3RVX A;  4W5C A;  3M99 A;  4KLB A;  3E1Z B;  1CPJ A;  3H89 A;  1EWP A;  1S4V A;  2NQA A;  1AU2 A;  2OZ2 A;  3LFY A;  4PP2 E;  1GMY A;  3CH3 X;  1MEM A;  2PRE A;  1KFU L;  2NQG A;  3ERV A;  3KX1 A;  1U9V A;  5J94 A;  2FYE A;  3IUT A;  2HH5 A;  3OIS A;  4CDF B;  3C9E A;  2R9M A;  3USV A;  4XR7 A;  2XU4 A;  5PAD A;  1YK7 A;  4Q8G A;  1IWD A;  4QRV A;  1CTE A;  3QT4 A;  3MHH A;  2AUZ A;  1PPP A;  1NB3 A;  4X6I A;  1K3B B;  3OF8 A;  4YYV A;  1TU6 A;  4P6E A;  4P6G A;  1AU0 A;  3H7D A;  3D6S A;  4X6H A;  2HHN A;  2GFO A;  4W5B A;  1CB5 A;  3PNR A;  4I04 A;  2GHU A;  2R9C A;  1YK8 A;  2ATO A;  2G6D A;  2CIO A;  3KFQ A;  1NPZ A;  3I06 A;  4QBB A;  4WA6 A;  4W4U A;  1U9Q X;  3P5U A;  1CJL A;  3KKU A;  2HD5 A;  2R9F A;  2E02 A;  5A24 A;  2PAD A;  2YJ8 A;  2G8E A;  3O0U A;  2B1N A;  2YJC A;  2R9N A;  1TL9 A;  1MIR A;  2E03 A;  1YT7 A;  1BQI A;  3IOQ A;  1CQD A;  3QSD A;  4XUI A;  2NQD B;  1ME3 A;  3PW3 A;  9PAP A;  2OP3 A;  2DCA A;  2ARY A;  1PBH A;  1SNK A;  3AI8 A;  3RVW A;  1AYV A;  2DCB A;  1TLO A;  3IHP A;  2DZY A;  2FRQ A;  2IPP B;  1PPO A;  5EF4 A;  3K9M A;  4OEL A;  1F2C A;  2C0Y A;  4YYS A;  2WBF X;  3KWB X;  3BC3 A;  3PDF A;  2Y6E A;  3V6E A;  1ATK A;  3GCB A;  2FO5 A;  1NB5 A;  4I07 A;  1PIP A;  1PPN A;  2DC6 A;  1BP4 A;  1CSB B;  1POP A;  1YVB A;  5JA7 A;  3H8C A;  1EF7 A;  1EWL A;  4I05 A;  1PCI A;  2DJG B;  1KXR A;  3WXE A;  1PE6 A;  4BS5 A;  1AYW A;  3P5X A;  4QRG A;  2XU1 A;  1AU4 A;  1DF0 A;  1PAD A;  1MDW A;  3F75 A;  4RY2 A;  3QJ3 A;  5CVM A;  3U8E A;  2BDL A;  5EGW A;  3F5V A;  6PAD A;  8PCH A;  3K8U A;  2H7J A;  2IBI A;  1CV8 A;  1ZCM A;  1QDQ A;  1DEU A;  4K7C A;  4MZO A;  5CHT A;  1ITO A;  2JQG R;  1CVZ A;  4BQV A;  4AXM A;  5CVO B;  2FUD A;  4QH6 A;  4ZUX U;  7PCK A;  4CDE B;  3O1G A;  1QXP A; 
#chains in the Genus database with same CATH topology
 1GLO A;  3PRP A;  2DCC A;  1YAL A;  4Q8H A;  3OVZ A;  4FJC A;  1Y08 A;  3ZUA A;  3HWN A;  3BCN A;  4N4Z A;  3BOW A;  4AXL A;  1VJV A;  3B79 A;  1MHW A;  1CS8 A;  1THE A;  1AYU A;  4IUM A;  4D8I A;  1F2B A;  4N79 A;  2G7Y A;  1UKF A;  1JQP A;  3KW9 A;  2DCD A;  1GCB A;  4OEM A;  2AS8 A;  2F7D A;  3LXS A;  1SP4 B;  3PBH A;  4BOQ A;  3RVV A;  4FK5 A;  1AIM A;  3TNX A;  3BPF A;  1Q6K A;  3IV2 A;  2R9O A;  3HD3 A;  1QMY A;  3P5V A;  4YYU A;  3HHI A;  2HWK A;  2PNS A;  3WXF A;  5JH3 A;  4QRX A;  2FT2 A;  4HXD B;  3B21 A;  2BDZ A;  4YYR A;  1NLJ A;  1F2A A;  3BWK A;  3H6S A;  2JRI A;  2DC8 A;  2F1G A;  4R3D A;  3MTN A;  4MSX A;  3H8B A;  2G8J A;  3BPM A;  4PI3 A;  1MEG A;  4CDC B;  4DMX A;  3KWZ A;  1KHP A;  5K16 A;  2FRA A;  2AYN A;  2E00 A;  1NQC A;  1STF E;  3IMA A;  1EWM A;  2BU3 A;  1U5I A;  2AIM A;  1KHQ A;  2P0R A;  1PPD A;  2FQ9 A;  2Y5B A;  4RF0 A;  2ACT A;  3HHA A;  4YV8 A;  5F02 A;  4PAD A;  1ZIV A;  3CBK A;  2R6N A;  1MS6 A;  2XU3 A;  2AYO A;  1A6R A;  4FIP A;  5CHV A;  4BPV A;  3KSE A;  3OVX A;  3PRM A;  4OVZ B;  1AEC A;  4YVA A;  3PT2 A;  4CZW A;  1PVJ A;  5EZQ A;  1HUC B;  2VHS A;  2XU5 A;  1GEC E;  3TRK A;  2JQF R;  2DC7 A;  2DZZ A;  1BGO A;  3BB7 A;  3N4C A;  4N8W A;  3K24 A;  2P7U A;  3P5W A;  4MZS A;  3S3R A;  4DMY A;  2FE8 A;  2JTC A;  1M6D A;  4M0W A;  2O6X A;  3OF9 A;  3IFU A;  3PHU A;  3PHW A;  3W31 A;  4BSQ A;  4BS6 A;  3MTV A;  2UZJ A;  3IEJ A;  1Y4H A;  3NHE A;  4YYW A;  3W30 A;  1U9W A;  3V6C A;  2CB5 A;  5CVN B;  4G54 A;  2YJ2 A;  2HXZ A;  3I3T A;  3MHS A;  4BOU A;  1VSN A;  1AU3 A;  1NL6 A;  1U9X A;  2B1M A;  4ZTB A;  2DJF B;  3DF0 A;  2AU1 A;  4BOS A;  2DC9 A;  1PXV A;  4HWY A;  5FPW A;  3CH2 X;  1FH0 A;  3CBJ A;  2J7Q C;  2PBH A;  4CDD B;  3N3K A;  1XKG A;  2Z84 A;  3S3Q A;  1O0E A;  2FTD A;  2AVW A;  3C0R A;  2VHF A;  2NQI A;  1X9Y A;  2P86 A;  1EWO A;  2E01 A;  1ICF A;  3N3G A;  4MM3 B;  3TMP A;  2OUL A;  2AUX A;  3MP2 A;  4YYQ A;  4X6J A;  1KFX L;  4XZX A;  1QOL A;  2YJB A;  1F29 A;  3WXG A;  2YJ9 A;  3MOR A;  1BY8 A;  1ME4 A;  4PP1 A;  3RVX A;  4W5C A;  3M99 A;  4KLB A;  3E1Z B;  1CPJ A;  3H89 A;  1EWP A;  1S4V A;  2NQA A;  1AU2 A;  2OZ2 A;  3ZNH A;  3LFY A;  4PP2 E;  1GMY A;  3CH3 X;  1MEM A;  3O65 A;  2PRE A;  1KFU L;  2NQG A;  3ERV A;  3KX1 A;  1U9V A;  5J94 A;  2FYE A;  3IUT A;  2HH5 A;  4RNA A;  3OIS A;  4CDF B;  3C9E A;  4OW0 A;  2R9M A;  3USV A;  4P16 A;  2J7Q A;  3MJ5 A;  4XR7 A;  2XU4 A;  4PT5 A;  5PAD A;  1YK7 A;  4Q8G A;  1IWD A;  4QRV A;  1CTE A;  1DKI A;  3QT4 A;  3MHH A;  2AUZ A;  1PPP A;  1NB3 A;  4X6I A;  1K3B B;  2BTW A;  3OF8 A;  4YYV A;  1TU6 A;  4P6E A;  4P6G A;  5KO3 A;  1AU0 A;  3H7D A;  3D6S A;  4X6H A;  2HHN A;  3OQC A;  2GFO A;  4W5B A;  5E6J A;  1CB5 A;  3PNR A;  4I04 A;  2GHU A;  2R9C A;  4D8E A;  1YK8 A;  2ATO A;  2G6D A;  2CIO A;  3KFQ A;  1NPZ A;  3I06 A;  4QBB A;  4WA6 A;  4W4U A;  1U9Q X;  3P5U A;  1CJL A;  3KKU A;  1YZB A;  2HD5 A;  2R9F A;  2E02 A;  5A24 A;  4GUA A;  2PAD A;  2YJ8 A;  2G8E A;  3O0U A;  2B1N A;  2YJC A;  2R9N A;  5EZS A;  1TL9 A;  1MIR A;  2E03 A;  1YT7 A;  1BQI A;  3IOQ A;  1CQD A;  3QSD A;  4XUI A;  2NQD B;  1ME3 A;  3PW3 A;  9PAP A;  2OP3 A;  2DCA A;  2ARY A;  1PBH A;  1SNK A;  3AI8 A;  3RVW A;  1AYV A;  5JZE A;  2DCB A;  1TLO A;  3IHP A;  2DZY A;  2FRQ A;  2IPP B;  1PPO A;  5EF4 A;  3K9M A;  4OEL A;  1F2C A;  2C0Y A;  4YYS A;  2WBF X;  3KWB X;  4IP3 A;  3BC3 A;  3PDF A;  2Y6E A;  4RF1 A;  3V6E A;  1ATK A;  3GCB A;  2FO5 A;  1NB5 A;  4I07 A;  4REZ A;  1PIP A;  1PPN A;  2DC6 A;  4D8B A;  3E9S A;  1BP4 A;  3BY4 A;  1CSB B;  1POP A;  1YVB A;  5JA7 A;  3H8C A;  1EF7 A;  1EWL A;  4I05 A;  1PCI A;  2DJG B;  1KXR A;  3WXE A;  3PHX A;  1PE6 A;  4BS5 A;  1AYW A;  3P5X A;  4MI7 A;  4QRG A;  2XU1 A;  3PSE A;  1AU4 A;  1DF0 A;  1PAD A;  1MDW A;  4BOZ A;  3F75 A;  4RY2 A;  3BBA A;  3QJ3 A;  5CVM A;  3U8E A;  2BDL A;  3RNV A;  5EGW A;  3F5V A;  2AGA A;  6PAD A;  8PCH A;  3K8U A;  2DOS A;  2H7J A;  2IBI A;  4OVZ A;  1CV8 A;  1ZCM A;  1QDQ A;  4BOP A;  1DEU A;  4K7C A;  4MZO A;  5CHT A;  1ITO A;  2JQG R;  1CVZ A;  4BQV A;  2BTW B;  4AXM A;  5CVO B;  2FUD A;  4RKX A;  4QH6 A;  4A5U A;  4WUR A;  4ZUX U;  7PCK A;  4CDE B;  3O1G A;  1QXP A; 
#chains in the Genus database with same CATH homology
 1GLO A;  4GUZ A;  2DCC A;  1YAL A;  4Q8H A;  3OVZ A;  4FJC A;  1Y08 A;  3ZUA A;  3HWN A;  3BCN A;  4N4Z A;  3BOW A;  4AXL A;  1VJV A;  3B79 A;  1MHW A;  1CS8 A;  1THE A;  1AYU A;  1W5R A;  1F2B A;  4N79 A;  2G7Y A;  1JQP A;  3KW9 A;  2DCD A;  1GCB A;  4OEM A;  2AS8 A;  2F7D A;  3LXS A;  1SP4 B;  3PBH A;  3RVV A;  4FK5 A;  1AIM A;  3TNX A;  3BPF A;  1Q6K A;  3IV2 A;  2R9O A;  3HD3 A;  1QMY A;  4NV7 A;  3P5V A;  4YYU A;  3HHI A;  2PNS A;  3WXF A;  5JH3 A;  4QRX A;  2FT2 A;  2BDZ A;  4YYR A;  1NLJ A;  1F2A A;  3BWK A;  3H6S A;  2DC8 A;  2F1G A;  3MTN A;  4MSX A;  3H8B A;  2G8J A;  3BPM A;  4PI3 A;  1MEG A;  4CDC B;  4DMX A;  3KWZ A;  1KHP A;  5K16 A;  2FRA A;  2AYN A;  2E00 A;  1NQC A;  1STF E;  3IMA A;  1EWM A;  1U5I A;  2AIM A;  1KHQ A;  2P0R A;  1PPD A;  2FQ9 A;  2Y5B A;  2ACT A;  3HHA A;  4YV8 A;  5F02 A;  4PAD A;  2VFB A;  1ZIV A;  3CBK A;  2R6N A;  1MS6 A;  2XU3 A;  2AYO A;  1A6R A;  4FIP A;  5CHV A;  4BPV A;  3KSE A;  3OVX A;  1AEC A;  4YVA A;  4CZW A;  1HUC B;  2VHS A;  2XU5 A;  1GEC E;  2JQF R;  2DC7 A;  2DZZ A;  1BGO A;  4N8W A;  3N4C A;  3K24 A;  2P7U A;  3P5W A;  4MZS A;  3S3R A;  4DMY A;  1M6D A;  2O6X A;  3OF9 A;  4BSQ A;  4BS6 A;  3IEJ A;  1Y4H A;  3NHE A;  4YYW A;  1U9W A;  3V6C A;  2CB5 A;  5CVN B;  4G54 A;  2YJ2 A;  2HXZ A;  3I3T A;  3MHS A;  1VSN A;  1AU3 A;  1NL6 A;  1U9X A;  2B1M A;  1W6F A;  2DJF B;  3DF0 A;  2AU1 A;  2DC9 A;  1PXV A;  4HWY A;  5FPW A;  3CH2 X;  1FH0 A;  3CBJ A;  2PBH A;  4CDD B;  3N3K A;  1XKG A;  3S3Q A;  1O0E A;  2FTD A;  2AVW A;  2VHF A;  2NQI A;  1X9Y A;  2P86 A;  1EWO A;  2E01 A;  1ICF A;  3N3G A;  2OUL A;  2AUX A;  4YYQ A;  4X6J A;  1KFX L;  4BGF A;  1QOL A;  2YJB A;  1F29 A;  3WXG A;  2YJ9 A;  3MOR A;  1BY8 A;  1ME4 A;  4PP1 A;  3RVX A;  4W5C A;  3M99 A;  4KLB A;  3LTW A;  3E1Z B;  1CPJ A;  3H89 A;  1EWP A;  1S4V A;  2NQA A;  1AU2 A;  2OZ2 A;  3LFY A;  4PP2 E;  1GMY A;  3CH3 X;  1MEM A;  2PRE A;  1KFU L;  2NQG A;  3ERV A;  3KX1 A;  1U9V A;  5J94 A;  2FYE A;  3IUT A;  2HH5 A;  3OIS A;  4CDF B;  4NV8 A;  3C9E A;  2R9M A;  3USV A;  4XR7 A;  2XU4 A;  5PAD A;  1YK7 A;  4Q8G A;  1IWD A;  4QRV A;  1CTE A;  3QT4 A;  3MHH A;  2AUZ A;  1PPP A;  1NB3 A;  4X6I A;  1K3B B;  3OF8 A;  4YYV A;  1TU6 A;  4P6E A;  4P6G A;  1AU0 A;  3H7D A;  3D6S A;  4X6H A;  2HHN A;  2GFO A;  4W5B A;  2BSZ A;  1CB5 A;  3PNR A;  4I04 A;  2GHU A;  2R9C A;  1YK8 A;  2ATO A;  2G6D A;  2CIO A;  3KFQ A;  1NPZ A;  3I06 A;  4QBB A;  1GX3 A;  4WA6 A;  4W4U A;  1U9Q X;  3P5U A;  1CJL A;  3KKU A;  2HD5 A;  2R9F A;  2E02 A;  5A24 A;  2PAD A;  2YJ8 A;  2G8E A;  3O0U A;  2B1N A;  2YJC A;  2R9N A;  1TL9 A;  1MIR A;  2E03 A;  1YT7 A;  1BQI A;  3IOQ A;  1CQD A;  3QSD A;  4XUI A;  2NQD B;  1ME3 A;  3PW3 A;  9PAP A;  2OP3 A;  2DCA A;  2ARY A;  1PBH A;  1SNK A;  3AI8 A;  2VFC A;  3RVW A;  1AYV A;  2DCB A;  1TLO A;  4C5P A;  3IHP A;  2DZY A;  2FRQ A;  2IPP B;  1PPO A;  5EF4 A;  3K9M A;  4OEL A;  1F2C A;  2C0Y A;  4YYS A;  2WBF X;  3KWB X;  3BC3 A;  3PDF A;  2Y6E A;  3V6E A;  1ATK A;  3GCB A;  2FO5 A;  1NB5 A;  4I07 A;  1PIP A;  1PPN A;  2DC6 A;  1BP4 A;  1CSB B;  1POP A;  1YVB A;  5JA7 A;  3H8C A;  1EF7 A;  1EWL A;  4I05 A;  1PCI A;  1W4T A;  2DJG B;  1KXR A;  3WXE A;  1PE6 A;  4BS5 A;  1AYW A;  3P5X A;  4QRG A;  2XU1 A;  1AU4 A;  1DF0 A;  1PAD A;  1MDW A;  1E2T A;  3F75 A;  3D9W A;  4RY2 A;  3QJ3 A;  5CVM A;  3U8E A;  2BDL A;  5EGW A;  3F5V A;  6PAD A;  8PCH A;  3K8U A;  2H7J A;  2IBI A;  1CV8 A;  1ZCM A;  1QDQ A;  1DEU A;  4K7C A;  4MZO A;  5CHT A;  1ITO A;  2JQG R;  1CVZ A;  4BQV A;  4AXM A;  5CVO B;  2FUD A;  4QH6 A;  4ZUX U;  4B55 A;  7PCK A;  4CDE B;  3O1G A;  1QXP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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