1TL9A

High resolution crystal structure of calpain i protease core in complex with leupeptin
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
321
structure length
321
Chain Sequence
b'NAIKYLGQDYENLRARCLQNGVLFQDDAFPPVSHSLGFKELGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNETILHRVVPYGQSFQEGYAGIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHSAQGNEFWSALLEKAYAKVNGSYEALSGGCTSEAFEDFTGGVTEWYDLQKAPSDLYQIILKALERGSLLGCSINISDIRDLEAITFKNLVRGHAYSVTDAKQVTYQGQRVNLIRMRNPWGEVEWKGPWSDNSYEWNKVDPYEREQLRVKMEDGEFWMSFRDFIREFTKLEICNL'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Calpain 1, large [catalytic] subunit
publication title Crystal Structures of Calpain-E64 and -Leupeptin Inhibitor Complexes Reveal Mobile Loops Gating the Active Site
pubmed doi rcsb
source organism Rattus norvegicus
molecule tags Hydrolase/hydrolase inhibitor
total genus 96
structure length 321
sequence length 321
ec nomenclature ec 3.4.22.52: Calpain-1.
pdb deposition date 2004-06-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00648 Peptidase_C2 Calpain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1tl9A02
3TNXA 1EWOA 2P0RA 3V6CA 4KLBA 1MIRA 2B1MA 4MZSA 2OZ2A 2CB5A 1CSBB 3H7DA 3OISA 4QRGA 2DCCA 1POPA 3PDFA 3O0UA 2DJGB 1CTEA 3HWNA 3IOQA 1EWPA 2NQAA 4PI3A 1AU4A 2Y5BA 3H6SA 4Q8HA 1VJVA 5K16A 1F2BA 1KHPA 1F2CA 1EWMA 3KSEA 2R9MA 2F1GA 2O6XA 3DF0A 4RY2A 3U8EA 1PCIA 1YT7A 2G7YA 2HHNA 4OEMA 1CB5A 3M99A 2YJ9A 3BPMA 3BOWA 4YYSA 1X9YA 3GCBA 3V6EA 1JQPA 4N79A 2XU3A 1PPDA 1KHQA 3O1GA 3CBJA 4N8WA 4YYQA 1VSNA 1Q6KA 3KFQA 2GFOA 3BPFA 2JQFR 3OF8A 2AUZA 3BC3A 3WXGA 2WBFX 1HUCB 3PW3A 2XU4A 3QJ3A 5CVOB 2DJFB 4YYVA 2AYNA 4QBBA 1KFXL 1S4VA 3K8UA 1PADA 2E00A 3AI8A 2YJCA 2AYOA 5PADA 2YJ8A 1M6DA 3NHEA 1QMYA 3C9EA 3BCNA 5CHVA 4P6EA 3HHAA 2G8JA 5CVNB 1ITOA 3KX1A 3B79A 1STFE 2ARYA 1NB5A 1F29A 2AUXA 1CPJA 1A6RA 1ATKA 2DZYA 1MEMA 1PPNA 3HD3A 1ICFA 4MZOA 2B1NA 3LXSA 2CIOA 3N3KA 1GCBA 3MHSA 1PPPA 1AU3A 2DZZA 2P86A 3K24A 2DC6A 4W4UA 2Y6EA 1BQIA 2FO5A 4HWYA 3USVA 1QDQA 2FRQA 2FUDA 1AU0A 2R9FA 2AS8A 4Q8GA 4N4ZA 2E01A 3LFYA 1CS8A 3BWKA 1YALA 3P5UA 4YVAA 4X6JA 3WXFA 1ME3A 4PP2E 3I06A 1NPZA 3I3TA 4YV8A 2ATOA 4W5BA 2G8EA 2VHSA 4BQVA 1O0EA 1PE6A 3QT4A 2XU1A 8PCHA 1AYUA 2NQIA 4AXLA 2HD5A 3K9MA 4BSQA 3MHHA 1TLOA 1CV8A 3RVWA 2FQ9A 3H8CA 1NL6A 5J94A 2PREA 3CH2X 4X6HA 2IPPB 1NB3A 2AIMA 1PPOA 1U9XA 3CBKA 2R9OA 1GMYA 1AIMA 4AXMA 2DC8A 2C0YA 3S3QA 1K3BB 2HXZA 4QRVA 2FRAA 2PBHA 3IHPA 2PADA 3P5WA 5A24A 2NQDB 3PNRA 2BDZA 1QOLA 4BS5A 4DMXA 1NQCA 1U9WA 1PXVA 2IBIA 1TU6A 2H7JA 5EF4A 1GECE 1AYVA 3N3GA 3KWZA 2R9CA 1DF0A 2AVWA 1U5IA 4OELA 3OVZA 1EF7A 4CZWA 4FIPA 3RVVA 9PAPA 5JA7A 2FTDA 4XR7A 2DCDA 2FT2A 5CVMA 1AYWA 3PBHA 4X6IA 3IEJA 3KKUA 1BGOA 1FH0A 4QH6A 1ZCMA 2JQGR 3E1ZB 1SNKA 3OVXA 1XKGA 1CQDA 1Y4HA 3H89A 1CJLA 2E02A 4DMYA 4I05A 2OP3A 4PP1A 1YK8A 2FYEA 1MHWA 4K7CA 2YJBA 1NLJA 3IV2A 3OF9A 1THEA 1KXRA 1YK7A 2ACTA 4XUIA 2G6DA 1ZIVA 6PADA 2F7DA 1EWLA 4ZUXU 5F02A 5CHTA 3ZUAA 4YYUA 1QXPA 4BS6A 1DEUA 5EGWA 2HH5A 1PIPA 1KFUL 1CVZA 1MEGA 2AU1A 4PADA 4I04A 3QSDA 1AU2A 2R9NA 2XU5A 4QRXA 2R6NA 3D6SA 4P6GA 4G54A 2NQGA 2VHFA 1GLOA 3KW9A 3IMAA 4CDDB 1AECA 3KWBX 1PBHA 7PCKA 3ERVA 1IWDA 3MORA 1MDWA 1ME4A 2P7UA 2DC7A 4CDEB 2PNSA 3WXEA 4FJCA 3P5VA 4CDCB 3F75A 3N4CA 3H8BA 4YYRA 2GHUA 4W5CA 3HHIA 1YVBA 3CH3X 4WA6A 3MTNA 2E03A 2OULA 1MS6A 5JH3A 4FK5A 3RVXA 4CDFB 4I07A 3F5VA 1SP4B 1BY8A 3IUTA 4BPVA 2DCAA 1F2AA 1TL9A 4MSXA 1U9VA 3P5XA 1BP4A 2YJ2A 5FPWA 2DCBA 4YYWA 1Y08A 2BDLA 2DC9A 1U9QX 3S3RA
chains in the Genus database with same CATH superfamily
3TNXA 1EWOA 2P0RA 3V6CA 4XZXA 4MM3B 4KLBA 1MIRA 2B1MA 4MZSA 2OZ2A 2CB5A 1CSBB 5JZEA 3H7DA 3OISA 4P16A 4QRGA 2DCCA 1POPA 3PDFA 3O0UA 2DJGB 1CTEA 3HWNA 2J7QC 3IOQA 1EWPA 2NQAA 4PI3A 1AU4A 2Y5BA 3H6SA 4Q8HA 1VJVA 3B21A 5K16A 1F2BA 1KHPA 3W30A 1F2CA 1EWMA 3KSEA 2R9MA 2F1GA 2O6XA 3RNVA 3DF0A 4RY2A 3U8EA 1PCIA 1YT7A 2G7YA 2HHNA 4OEMA 1CB5A 3M99A 2YJ9A 3BPMA 2UZJA 3BOWA 4YYSA 1X9YA 3GCBA 4RKXA 2BU3A 3V6EA 3IFUA 1JQPA 4N79A 2XU3A 1PPDA 1KHQA 3O1GA 3CBJA 4N8WA 4YYQA 1VSNA 3PRPA 1Q6KA 3KFQA 2GFOA 3BPFA 2JQFR 3OF8A 2J7QA 2AUZA 3BC3A 3PSEA 3WXGA 2WBFX 1HUCB 3PW3A 2XU4A 3QJ3A 5CVOB 2DJFB 4YYVA 2AYNA 4BOQA 4REZA 4QBBA 1KFXL 5KO3A 1S4VA 3K8UA 4D8EA 1PADA 2E00A 3AI8A 4RF1A 4IP3A 2YJCA 2AYOA 5PADA 2YJ8A 1M6DA 3NHEA 1QMYA 3C9EA 3BCNA 5CHVA 4P6EA 3BBAA 3HHAA 2G8JA 5CVNB 1ITOA 3KX1A 3B79A 1STFE 4BOSA 2ARYA 1NB5A 1F29A 2AUXA 2FE8A 1CPJA 1A6RA 1ATKA 2DZYA 1MEMA 1PPNA 3HD3A 1ICFA 4MZOA 3MJ5A 2B1NA 3W31A 3LXSA 2CIOA 3N3KA 4OW0A 1GCBA 3MHSA 1PPPA 3TRKA 1AU3A 2DZZA 2P86A 3K24A 1PVJA 2DC6A 4W4UA 2Y6EA 1BQIA 2FO5A 4HWYA 2JTCA 3USVA 1QDQA 2FRQA 2FUDA 1AU0A 2R9FA 2AS8A 4Q8GA 4N4ZA 2E01A 2HWKA 3LFYA 1CS8A 3BWKA 1YALA 3BB7A 3P5UA 4YVAA 4X6JA 3WXFA 1ME3A 4PP2E 3I06A 3ZNHA 4PT5A 1NPZA 3I3TA 4YV8A 2ATOA 4W5BA 2G8EA 2VHSA 4BQVA 1O0EA 1PE6A 3QT4A 2XU1A 8PCHA 1AYUA 2NQIA 4AXLA 2HD5A 3K9MA 4BSQA 3MHHA 1TLOA 1CV8A 3RVWA 2FQ9A 3H8CA 1NL6A 5J94A 2PREA 3CH2X 4X6HA 2IPPB 1NB3A 2AIMA 1PPOA 1U9XA 3CBKA 2R9OA 1GMYA 1AIMA 4AXMA 2DC8A 2C0YA 3S3QA 1K3BB 2HXZA 4QRVA 3TMPA 2FRAA 2PBHA 3IHPA 5EZQA 2PADA 3P5WA 5A24A 2NQDB 3PNRA 2BDZA 1QOLA 4RNAA 4BS5A 4DMXA 3O65A 1NQCA 2Z84A 1U9WA 1PXVA 2IBIA 1TU6A 4D8IA 2H7JA 4M0WA 1GECE 5EF4A 1AYVA 3N3GA 3KWZA 2R9CA 1DF0A 2AVWA 1U5IA 1DKIA 4OELA 3OVZA 3MP2A 1EF7A 2BTWA 4BOPA 4HXDB 4CZWA 3E9SA 4FIPA 2DOSA 3RVVA 9PAPA 5JA7A 4MI7A 4D8BA 2FTDA 4XR7A 2DCDA 2FT2A 5CVMA 2JRIA 1AYWA 3PBHA 4X6IA 3IEJA 3OQCA 3KKUA 1BGOA 1FH0A 4QH6A 1ZCMA 2JQGR 3E1ZB 1SNKA 4OVZA 3PHWA 3OVXA 4GUAA 1XKGA 1CQDA 1Y4HA 3H89A 1CJLA 2E02A 4DMYA 4I05A 2OP3A 4PP1A 1YK8A 2FYEA 1MHWA 4K7CA 3PHUA 2YJBA 1NLJA 3IV2A 3OF9A 1THEA 1KXRA 1YK7A 2ACTA 3BY4A 4XUIA 2G6DA 1ZIVA 6PADA 2F7DA 4WURA 1EWLA 4A5UA 1UKFA 4ZUXU 5F02A 2AGAA 3PHXA 5CHTA 3ZUAA 4YYUA 1QXPA 4BS6A 5E6JA 4IUMA 1DEUA 5EGWA 2HH5A 3PRMA 1PIPA 1KFUL 1CVZA 1MEGA 2AU1A 4PADA 4I04A 3QSDA 1AU2A 2R9NA 2XU5A 4QRXA 2R6NA 3D6SA 4P6GA 4G54A 3MTVA 2NQGA 2VHFA 1GLOA 3PT2A 1YZBA 3KW9A 3IMAA 4CDDB 1AECA 4BOZA 3KWBX 1PBHA 7PCKA 3ERVA 1IWDA 2BTWB 3MORA 1MDWA 1ME4A 2P7UA 2DC7A 4CDEB 2PNSA 3WXEA 4R3DA 4FJCA 3P5VA 4CDCB 3F75A 4BOUA 3N4CA 3H8BA 4YYRA 2GHUA 4W5CA 3HHIA 1YVBA 3CH3X 4WA6A 3MTNA 2E03A 4RF0A 5EZSA 2OULA 4ZTBA 1MS6A 5JH3A 4FK5A 3C0RA 3RVXA 4CDFB 4I07A 3F5VA 1SP4B 1BY8A 3IUTA 4OVZB 4BPVA 2DCAA 1F2AA 1TL9A 4MSXA 1U9VA 3P5XA 1BP4A 2YJ2A 5FPWA 2DCBA 4YYWA 1Y08A 2BDLA 2DC9A 1U9QX 3S3RA
chains in the Genus database with same CATH topology
3TNXA 1EWOA 2P0RA 3V6CA 1W6FA 4KLBA 1MIRA 2B1MA 4MZSA 2OZ2A 2CB5A 1CSBB 3H7DA 1W4TA 3OISA 4QRGA 2DCCA 1POPA 3PDFA 3O0UA 2DJGB 1CTEA 3HWNA 3IOQA 1EWPA 2NQAA 4PI3A 1AU4A 2Y5BA 3H6SA 4Q8HA 1VJVA 5K16A 1F2BA 1KHPA 1F2CA 1EWMA 3KSEA 2R9MA 2F1GA 2O6XA 3DF0A 4RY2A 3U8EA 1PCIA 1YT7A 2G7YA 2HHNA 4OEMA 1CB5A 3M99A 2YJ9A 3BPMA 4NV7A 3BOWA 4YYSA 1X9YA 3GCBA 3V6EA 2VFCA 1JQPA 4N79A 2XU3A 4GUZA 1PPDA 1KHQA 3O1GA 3CBJA 4N8WA 4YYQA 1VSNA 1Q6KA 3KFQA 2GFOA 3BPFA 2JQFR 3OF8A 2AUZA 3BC3A 3WXGA 2WBFX 1HUCB 3PW3A 2XU4A 3QJ3A 5CVOB 2DJFB 4YYVA 2AYNA 4QBBA 1KFXL 1S4VA 1E2TA 3K8UA 1PADA 2E00A 3AI8A 2YJCA 2AYOA 5PADA 2YJ8A 1M6DA 3NHEA 1QMYA 3C9EA 3BCNA 5CHVA 4P6EA 3HHAA 2G8JA 5CVNB 1ITOA 3KX1A 3B79A 1STFE 2ARYA 1NB5A 1F29A 2AUXA 1CPJA 1A6RA 1ATKA 2DZYA 1MEMA 1PPNA 3HD3A 1ICFA 4MZOA 2B1NA 3LXSA 2CIOA 3N3KA 1GCBA 3MHSA 1PPPA 1AU3A 2DZZA 2P86A 3K24A 2DC6A 4W4UA 2Y6EA 1BQIA 2FO5A 4HWYA 3USVA 1QDQA 2FRQA 2FUDA 1AU0A 2R9FA 2AS8A 4Q8GA 4N4ZA 2E01A 3LFYA 1CS8A 3BWKA 1YALA 3P5UA 4YVAA 4X6JA 3WXFA 1ME3A 4PP2E 3I06A 1NPZA 3I3TA 4YV8A 2ATOA 4W5BA 2G8EA 2VHSA 4BQVA 1O0EA 1PE6A 3QT4A 2XU1A 8PCHA 1AYUA 2NQIA 4AXLA 2HD5A 3K9MA 4BSQA 3MHHA 1TLOA 1CV8A 3RVWA 3LTWA 2FQ9A 3H8CA 1NL6A 5J94A 2PREA 3CH2X 4X6HA 2IPPB 1NB3A 2AIMA 1PPOA 1U9XA 3CBKA 2R9OA 1GMYA 1AIMA 2VFBA 4AXMA 2DC8A 2C0YA 3S3QA 1K3BB 2HXZA 4QRVA 4NV8A 2FRAA 2PBHA 4B55A 3IHPA 2PADA 3P5WA 5A24A 2NQDB 3PNRA 2BDZA 1QOLA 4BS5A 4DMXA 1NQCA 1U9WA 1PXVA 2IBIA 1TU6A 2H7JA 5EF4A 1GECE 1AYVA 3N3GA 3KWZA 2R9CA 1DF0A 2AVWA 1U5IA 4OELA 3OVZA 1EF7A 1GX3A 4CZWA 4FIPA 4BGFA 3RVVA 9PAPA 5JA7A 2FTDA 4XR7A 2DCDA 2FT2A 5CVMA 1AYWA 3PBHA 4X6IA 3IEJA 3KKUA 1BGOA 1FH0A 4QH6A 1ZCMA 2JQGR 3E1ZB 1SNKA 3OVXA 1XKGA 1CQDA 1Y4HA 3H89A 1CJLA 2E02A 4DMYA 4I05A 2OP3A 4PP1A 1YK8A 2FYEA 1MHWA 4K7CA 2YJBA 1NLJA 3IV2A 3OF9A 1THEA 1KXRA 1YK7A 2ACTA 4XUIA 2G6DA 1ZIVA 6PADA 2F7DA 1EWLA 4ZUXU 5F02A 5CHTA 3ZUAA 4YYUA 1QXPA 4BS6A 1DEUA 5EGWA 2HH5A 3D9WA 1PIPA 1KFUL 1CVZA 1MEGA 2AU1A 4PADA 4I04A 3QSDA 1AU2A 2R9NA 2XU5A 4QRXA 2R6NA 3D6SA 4P6GA 4G54A 2NQGA 2VHFA 1GLOA 3KW9A 3IMAA 4CDDB 1AECA 3KWBX 2BSZA 1PBHA 7PCKA 3ERVA 1IWDA 3MORA 1MDWA 1ME4A 2P7UA 2DC7A 4CDEB 2PNSA 3WXEA 4FJCA 3P5VA 4CDCB 3F75A 3N4CA 3H8BA 4YYRA 2GHUA 4W5CA 3HHIA 1YVBA 3CH3X 4WA6A 3MTNA 2E03A 4C5PA 2OULA 1MS6A 5JH3A 4FK5A 3RVXA 4CDFB 4I07A 3F5VA 1SP4B 1BY8A 3IUTA 4BPVA 2DCAA 1F2AA 1W5RA 1TL9A 4MSXA 1U9VA 3P5XA 1BP4A 2YJ2A 5FPWA 2DCBA 4YYWA 1Y08A 2BDLA 2DC9A 1U9QX 3S3RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TNX A;  1EWO A;  2P0R A;  3V6C A;  4KLB A;  1MIR A;  2B1M A;  4MZS A;  2OZ2 A;  2CB5 A;  1CSB B;  3H7D A;  3OIS A;  4QRG A;  2DCC A;  1POP A;  3PDF A;  3O0U A;  2DJG B;  1CTE A;  3HWN A;  3IOQ A;  1EWP A;  2NQA A;  4PI3 A;  1AU4 A;  2Y5B A;  3H6S A;  4Q8H A;  1VJV A;  5K16 A;  1F2B A;  1KHP A;  1F2C A;  1EWM A;  3KSE A;  2R9M A;  2F1G A;  2O6X A;  3DF0 A;  4RY2 A;  3U8E A;  1PCI A;  1YT7 A;  2G7Y A;  2HHN A;  4OEM A;  1CB5 A;  3M99 A;  2YJ9 A;  3BPM A;  3BOW A;  4YYS A;  1X9Y A;  3GCB A;  3V6E A;  1JQP A;  4N79 A;  2XU3 A;  1PPD A;  1KHQ A;  3O1G A;  3CBJ A;  4N8W A;  4YYQ A;  1VSN A;  1Q6K A;  3KFQ A;  2GFO A;  3BPF A;  2JQF R;  3OF8 A;  2AUZ A;  3BC3 A;  3WXG A;  2WBF X;  1HUC B;  3PW3 A;  2XU4 A;  3QJ3 A;  5CVO B;  2DJF B;  4YYV A;  2AYN A;  4QBB A;  1KFX L;  1S4V A;  3K8U A;  1PAD A;  2E00 A;  3AI8 A;  2YJC A;  2AYO A;  5PAD A;  2YJ8 A;  1M6D A;  3NHE A;  1QMY A;  3C9E A;  3BCN A;  5CHV A;  4P6E A;  3HHA A;  2G8J A;  5CVN B;  1ITO A;  3KX1 A;  3B79 A;  1STF E;  2ARY A;  1NB5 A;  1F29 A;  2AUX A;  1CPJ A;  1A6R A;  1ATK A;  2DZY A;  1MEM A;  1PPN A;  3HD3 A;  1ICF A;  4MZO A;  2B1N A;  3LXS A;  2CIO A;  3N3K A;  1GCB A;  3MHS A;  1PPP A;  1AU3 A;  2DZZ A;  2P86 A;  3K24 A;  2DC6 A;  4W4U A;  2Y6E A;  1BQI A;  2FO5 A;  4HWY A;  3USV A;  1QDQ A;  2FRQ A;  2FUD A;  1AU0 A;  2R9F A;  2AS8 A;  4Q8G A;  4N4Z A;  2E01 A;  3LFY A;  1CS8 A;  3BWK A;  1YAL A;  3P5U A;  4YVA A;  4X6J A;  3WXF A;  1ME3 A;  4PP2 E;  3I06 A;  1NPZ A;  3I3T A;  4YV8 A;  2ATO A;  4W5B A;  2G8E A;  2VHS A;  4BQV A;  1O0E A;  1PE6 A;  3QT4 A;  2XU1 A;  8PCH A;  1AYU A;  2NQI A;  4AXL A;  2HD5 A;  3K9M A;  4BSQ A;  3MHH A;  1TLO A;  1CV8 A;  3RVW A;  2FQ9 A;  3H8C A;  1NL6 A;  5J94 A;  2PRE A;  3CH2 X;  4X6H A;  2IPP B;  1NB3 A;  2AIM A;  1PPO A;  1U9X A;  3CBK A;  2R9O A;  1GMY A;  1AIM A;  4AXM A;  2DC8 A;  2C0Y A;  3S3Q A;  1K3B B;  2HXZ A;  4QRV A;  2FRA A;  2PBH A;  3IHP A;  2PAD A;  3P5W A;  5A24 A;  2NQD B;  3PNR A;  2BDZ A;  1QOL A;  4BS5 A;  4DMX A;  1NQC A;  1U9W A;  1PXV A;  2IBI A;  1TU6 A;  2H7J A;  5EF4 A;  1GEC E;  1AYV A;  3N3G A;  3KWZ A;  2R9C A;  1DF0 A;  2AVW A;  1U5I A;  4OEL A;  3OVZ A;  1EF7 A;  4CZW A;  4FIP A;  3RVV A;  9PAP A;  5JA7 A;  2FTD A;  4XR7 A;  2DCD A;  2FT2 A;  5CVM A;  1AYW A;  3PBH A;  4X6I A;  3IEJ A;  3KKU A;  1BGO A;  1FH0 A;  4QH6 A;  1ZCM A;  2JQG R;  3E1Z B;  1SNK A;  3OVX A;  1XKG A;  1CQD A;  1Y4H A;  3H89 A;  1CJL A;  2E02 A;  4DMY A;  4I05 A;  2OP3 A;  4PP1 A;  1YK8 A;  2FYE A;  1MHW A;  4K7C A;  2YJB A;  1NLJ A;  3IV2 A;  3OF9 A;  1THE A;  1KXR A;  1YK7 A;  2ACT A;  4XUI A;  2G6D A;  1ZIV A;  6PAD A;  2F7D A;  1EWL A;  4ZUX U;  5F02 A;  5CHT A;  3ZUA A;  4YYU A;  1QXP A;  4BS6 A;  1DEU A;  5EGW A;  2HH5 A;  1PIP A;  1KFU L;  1CVZ A;  1MEG A;  2AU1 A;  4PAD A;  4I04 A;  3QSD A;  1AU2 A;  2R9N A;  2XU5 A;  4QRX A;  2R6N A;  3D6S A;  4P6G A;  4G54 A;  2NQG A;  2VHF A;  1GLO A;  3KW9 A;  3IMA A;  4CDD B;  1AEC A;  3KWB X;  1PBH A;  7PCK A;  3ERV A;  1IWD A;  3MOR A;  1MDW A;  1ME4 A;  2P7U A;  2DC7 A;  4CDE B;  2PNS A;  3WXE A;  4FJC A;  3P5V A;  4CDC B;  3F75 A;  3N4C A;  3H8B A;  4YYR A;  2GHU A;  4W5C A;  3HHI A;  1YVB A;  3CH3 X;  4WA6 A;  3MTN A;  2E03 A;  2OUL A;  1MS6 A;  5JH3 A;  4FK5 A;  3RVX A;  4CDF B;  4I07 A;  3F5V A;  1SP4 B;  1BY8 A;  3IUT A;  4BPV A;  2DCA A;  1F2A A;  1TL9 A;  4MSX A;  1U9V A;  3P5X A;  1BP4 A;  2YJ2 A;  5FPW A;  2DCB A;  4YYW A;  1Y08 A;  2BDL A;  2DC9 A;  1U9Q X;  3S3R A; 
#chains in the Genus database with same CATH topology
 3TNX A;  1EWO A;  2P0R A;  3V6C A;  4XZX A;  4MM3 B;  4KLB A;  1MIR A;  2B1M A;  4MZS A;  2OZ2 A;  2CB5 A;  1CSB B;  5JZE A;  3H7D A;  3OIS A;  4P16 A;  4QRG A;  2DCC A;  1POP A;  3PDF A;  3O0U A;  2DJG B;  1CTE A;  3HWN A;  2J7Q C;  3IOQ A;  1EWP A;  2NQA A;  4PI3 A;  1AU4 A;  2Y5B A;  3H6S A;  4Q8H A;  1VJV A;  3B21 A;  5K16 A;  1F2B A;  1KHP A;  3W30 A;  1F2C A;  1EWM A;  3KSE A;  2R9M A;  2F1G A;  2O6X A;  3RNV A;  3DF0 A;  4RY2 A;  3U8E A;  1PCI A;  1YT7 A;  2G7Y A;  2HHN A;  4OEM A;  1CB5 A;  3M99 A;  2YJ9 A;  3BPM A;  2UZJ A;  3BOW A;  4YYS A;  1X9Y A;  3GCB A;  4RKX A;  2BU3 A;  3V6E A;  3IFU A;  1JQP A;  4N79 A;  2XU3 A;  1PPD A;  1KHQ A;  3O1G A;  3CBJ A;  4N8W A;  4YYQ A;  1VSN A;  3PRP A;  1Q6K A;  3KFQ A;  2GFO A;  3BPF A;  2JQF R;  3OF8 A;  2J7Q A;  2AUZ A;  3BC3 A;  3PSE A;  3WXG A;  2WBF X;  1HUC B;  3PW3 A;  2XU4 A;  3QJ3 A;  5CVO B;  2DJF B;  4YYV A;  2AYN A;  4BOQ A;  4REZ A;  4QBB A;  1KFX L;  5KO3 A;  1S4V A;  3K8U A;  4D8E A;  1PAD A;  2E00 A;  3AI8 A;  4RF1 A;  4IP3 A;  2YJC A;  2AYO A;  5PAD A;  2YJ8 A;  1M6D A;  3NHE A;  1QMY A;  3C9E A;  3BCN A;  5CHV A;  4P6E A;  3BBA A;  3HHA A;  2G8J A;  5CVN B;  1ITO A;  3KX1 A;  3B79 A;  1STF E;  4BOS A;  2ARY A;  1NB5 A;  1F29 A;  2AUX A;  2FE8 A;  1CPJ A;  1A6R A;  1ATK A;  2DZY A;  1MEM A;  1PPN A;  3HD3 A;  1ICF A;  4MZO A;  3MJ5 A;  2B1N A;  3W31 A;  3LXS A;  2CIO A;  3N3K A;  4OW0 A;  1GCB A;  3MHS A;  1PPP A;  3TRK A;  1AU3 A;  2DZZ A;  2P86 A;  3K24 A;  1PVJ A;  2DC6 A;  4W4U A;  2Y6E A;  1BQI A;  2FO5 A;  4HWY A;  2JTC A;  3USV A;  1QDQ A;  2FRQ A;  2FUD A;  1AU0 A;  2R9F A;  2AS8 A;  4Q8G A;  4N4Z A;  2E01 A;  2HWK A;  3LFY A;  1CS8 A;  3BWK A;  1YAL A;  3BB7 A;  3P5U A;  4YVA A;  4X6J A;  3WXF A;  1ME3 A;  4PP2 E;  3I06 A;  3ZNH A;  4PT5 A;  1NPZ A;  3I3T A;  4YV8 A;  2ATO A;  4W5B A;  2G8E A;  2VHS A;  4BQV A;  1O0E A;  1PE6 A;  3QT4 A;  2XU1 A;  8PCH A;  1AYU A;  2NQI A;  4AXL A;  2HD5 A;  3K9M A;  4BSQ A;  3MHH A;  1TLO A;  1CV8 A;  3RVW A;  2FQ9 A;  3H8C A;  1NL6 A;  5J94 A;  2PRE A;  3CH2 X;  4X6H A;  2IPP B;  1NB3 A;  2AIM A;  1PPO A;  1U9X A;  3CBK A;  2R9O A;  1GMY A;  1AIM A;  4AXM A;  2DC8 A;  2C0Y A;  3S3Q A;  1K3B B;  2HXZ A;  4QRV A;  3TMP A;  2FRA A;  2PBH A;  3IHP A;  5EZQ A;  2PAD A;  3P5W A;  5A24 A;  2NQD B;  3PNR A;  2BDZ A;  1QOL A;  4RNA A;  4BS5 A;  4DMX A;  3O65 A;  1NQC A;  2Z84 A;  1U9W A;  1PXV A;  2IBI A;  1TU6 A;  4D8I A;  2H7J A;  4M0W A;  1GEC E;  5EF4 A;  1AYV A;  3N3G A;  3KWZ A;  2R9C A;  1DF0 A;  2AVW A;  1U5I A;  1DKI A;  4OEL A;  3OVZ A;  3MP2 A;  1EF7 A;  2BTW A;  4BOP A;  4HXD B;  4CZW A;  3E9S A;  4FIP A;  2DOS A;  3RVV A;  9PAP A;  5JA7 A;  4MI7 A;  4D8B A;  2FTD A;  4XR7 A;  2DCD A;  2FT2 A;  5CVM A;  2JRI A;  1AYW A;  3PBH A;  4X6I A;  3IEJ A;  3OQC A;  3KKU A;  1BGO A;  1FH0 A;  4QH6 A;  1ZCM A;  2JQG R;  3E1Z B;  1SNK A;  4OVZ A;  3PHW A;  3OVX A;  4GUA A;  1XKG A;  1CQD A;  1Y4H A;  3H89 A;  1CJL A;  2E02 A;  4DMY A;  4I05 A;  2OP3 A;  4PP1 A;  1YK8 A;  2FYE A;  1MHW A;  4K7C A;  3PHU A;  2YJB A;  1NLJ A;  3IV2 A;  3OF9 A;  1THE A;  1KXR A;  1YK7 A;  2ACT A;  3BY4 A;  4XUI A;  2G6D A;  1ZIV A;  6PAD A;  2F7D A;  4WUR A;  1EWL A;  4A5U A;  1UKF A;  4ZUX U;  5F02 A;  2AGA A;  3PHX A;  5CHT A;  3ZUA A;  4YYU A;  1QXP A;  4BS6 A;  5E6J A;  4IUM A;  1DEU A;  5EGW A;  2HH5 A;  3PRM A;  1PIP A;  1KFU L;  1CVZ A;  1MEG A;  2AU1 A;  4PAD A;  4I04 A;  3QSD A;  1AU2 A;  2R9N A;  2XU5 A;  4QRX A;  2R6N A;  3D6S A;  4P6G A;  4G54 A;  3MTV A;  2NQG A;  2VHF A;  1GLO A;  3PT2 A;  1YZB A;  3KW9 A;  3IMA A;  4CDD B;  1AEC A;  4BOZ A;  3KWB X;  1PBH A;  7PCK A;  3ERV A;  1IWD A;  2BTW B;  3MOR A;  1MDW A;  1ME4 A;  2P7U A;  2DC7 A;  4CDE B;  2PNS A;  3WXE A;  4R3D A;  4FJC A;  3P5V A;  4CDC B;  3F75 A;  4BOU A;  3N4C A;  3H8B A;  4YYR A;  2GHU A;  4W5C A;  3HHI A;  1YVB A;  3CH3 X;  4WA6 A;  3MTN A;  2E03 A;  4RF0 A;  5EZS A;  2OUL A;  4ZTB A;  1MS6 A;  5JH3 A;  4FK5 A;  3C0R A;  3RVX A;  4CDF B;  4I07 A;  3F5V A;  1SP4 B;  1BY8 A;  3IUT A;  4OVZ B;  4BPV A;  2DCA A;  1F2A A;  1TL9 A;  4MSX A;  1U9V A;  3P5X A;  1BP4 A;  2YJ2 A;  5FPW A;  2DCB A;  4YYW A;  1Y08 A;  2BDL A;  2DC9 A;  1U9Q X;  3S3R A; 
#chains in the Genus database with same CATH homology
 3TNX A;  1EWO A;  2P0R A;  3V6C A;  1W6F A;  4KLB A;  1MIR A;  2B1M A;  4MZS A;  2OZ2 A;  2CB5 A;  1CSB B;  3H7D A;  1W4T A;  3OIS A;  4QRG A;  2DCC A;  1POP A;  3PDF A;  3O0U A;  2DJG B;  1CTE A;  3HWN A;  3IOQ A;  1EWP A;  2NQA A;  4PI3 A;  1AU4 A;  2Y5B A;  3H6S A;  4Q8H A;  1VJV A;  5K16 A;  1F2B A;  1KHP A;  1F2C A;  1EWM A;  3KSE A;  2R9M A;  2F1G A;  2O6X A;  3DF0 A;  4RY2 A;  3U8E A;  1PCI A;  1YT7 A;  2G7Y A;  2HHN A;  4OEM A;  1CB5 A;  3M99 A;  2YJ9 A;  3BPM A;  4NV7 A;  3BOW A;  4YYS A;  1X9Y A;  3GCB A;  3V6E A;  2VFC A;  1JQP A;  4N79 A;  2XU3 A;  4GUZ A;  1PPD A;  1KHQ A;  3O1G A;  3CBJ A;  4N8W A;  4YYQ A;  1VSN A;  1Q6K A;  3KFQ A;  2GFO A;  3BPF A;  2JQF R;  3OF8 A;  2AUZ A;  3BC3 A;  3WXG A;  2WBF X;  1HUC B;  3PW3 A;  2XU4 A;  3QJ3 A;  5CVO B;  2DJF B;  4YYV A;  2AYN A;  4QBB A;  1KFX L;  1S4V A;  1E2T A;  3K8U A;  1PAD A;  2E00 A;  3AI8 A;  2YJC A;  2AYO A;  5PAD A;  2YJ8 A;  1M6D A;  3NHE A;  1QMY A;  3C9E A;  3BCN A;  5CHV A;  4P6E A;  3HHA A;  2G8J A;  5CVN B;  1ITO A;  3KX1 A;  3B79 A;  1STF E;  2ARY A;  1NB5 A;  1F29 A;  2AUX A;  1CPJ A;  1A6R A;  1ATK A;  2DZY A;  1MEM A;  1PPN A;  3HD3 A;  1ICF A;  4MZO A;  2B1N A;  3LXS A;  2CIO A;  3N3K A;  1GCB A;  3MHS A;  1PPP A;  1AU3 A;  2DZZ A;  2P86 A;  3K24 A;  2DC6 A;  4W4U A;  2Y6E A;  1BQI A;  2FO5 A;  4HWY A;  3USV A;  1QDQ A;  2FRQ A;  2FUD A;  1AU0 A;  2R9F A;  2AS8 A;  4Q8G A;  4N4Z A;  2E01 A;  3LFY A;  1CS8 A;  3BWK A;  1YAL A;  3P5U A;  4YVA A;  4X6J A;  3WXF A;  1ME3 A;  4PP2 E;  3I06 A;  1NPZ A;  3I3T A;  4YV8 A;  2ATO A;  4W5B A;  2G8E A;  2VHS A;  4BQV A;  1O0E A;  1PE6 A;  3QT4 A;  2XU1 A;  8PCH A;  1AYU A;  2NQI A;  4AXL A;  2HD5 A;  3K9M A;  4BSQ A;  3MHH A;  1TLO A;  1CV8 A;  3RVW A;  3LTW A;  2FQ9 A;  3H8C A;  1NL6 A;  5J94 A;  2PRE A;  3CH2 X;  4X6H A;  2IPP B;  1NB3 A;  2AIM A;  1PPO A;  1U9X A;  3CBK A;  2R9O A;  1GMY A;  1AIM A;  2VFB A;  4AXM A;  2DC8 A;  2C0Y A;  3S3Q A;  1K3B B;  2HXZ A;  4QRV A;  4NV8 A;  2FRA A;  2PBH A;  4B55 A;  3IHP A;  2PAD A;  3P5W A;  5A24 A;  2NQD B;  3PNR A;  2BDZ A;  1QOL A;  4BS5 A;  4DMX A;  1NQC A;  1U9W A;  1PXV A;  2IBI A;  1TU6 A;  2H7J A;  5EF4 A;  1GEC E;  1AYV A;  3N3G A;  3KWZ A;  2R9C A;  1DF0 A;  2AVW A;  1U5I A;  4OEL A;  3OVZ A;  1EF7 A;  1GX3 A;  4CZW A;  4FIP A;  4BGF A;  3RVV A;  9PAP A;  5JA7 A;  2FTD A;  4XR7 A;  2DCD A;  2FT2 A;  5CVM A;  1AYW A;  3PBH A;  4X6I A;  3IEJ A;  3KKU A;  1BGO A;  1FH0 A;  4QH6 A;  1ZCM A;  2JQG R;  3E1Z B;  1SNK A;  3OVX A;  1XKG A;  1CQD A;  1Y4H A;  3H89 A;  1CJL A;  2E02 A;  4DMY A;  4I05 A;  2OP3 A;  4PP1 A;  1YK8 A;  2FYE A;  1MHW A;  4K7C A;  2YJB A;  1NLJ A;  3IV2 A;  3OF9 A;  1THE A;  1KXR A;  1YK7 A;  2ACT A;  4XUI A;  2G6D A;  1ZIV A;  6PAD A;  2F7D A;  1EWL A;  4ZUX U;  5F02 A;  5CHT A;  3ZUA A;  4YYU A;  1QXP A;  4BS6 A;  1DEU A;  5EGW A;  2HH5 A;  3D9W A;  1PIP A;  1KFU L;  1CVZ A;  1MEG A;  2AU1 A;  4PAD A;  4I04 A;  3QSD A;  1AU2 A;  2R9N A;  2XU5 A;  4QRX A;  2R6N A;  3D6S A;  4P6G A;  4G54 A;  2NQG A;  2VHF A;  1GLO A;  3KW9 A;  3IMA A;  4CDD B;  1AEC A;  3KWB X;  2BSZ A;  1PBH A;  7PCK A;  3ERV A;  1IWD A;  3MOR A;  1MDW A;  1ME4 A;  2P7U A;  2DC7 A;  4CDE B;  2PNS A;  3WXE A;  4FJC A;  3P5V A;  4CDC B;  3F75 A;  3N4C A;  3H8B A;  4YYR A;  2GHU A;  4W5C A;  3HHI A;  1YVB A;  3CH3 X;  4WA6 A;  3MTN A;  2E03 A;  4C5P A;  2OUL A;  1MS6 A;  5JH3 A;  4FK5 A;  3RVX A;  4CDF B;  4I07 A;  3F5V A;  1SP4 B;  1BY8 A;  3IUT A;  4BPV A;  2DCA A;  1F2A A;  1W5R A;  1TL9 A;  4MSX A;  1U9V A;  3P5X A;  1BP4 A;  2YJ2 A;  5FPW A;  2DCB A;  4YYW A;  1Y08 A;  2BDL A;  2DC9 A;  1U9Q X;  3S3R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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