1TL9A

High resolution crystal structure of calpain i protease core in complex with leupeptin
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
321
structure length
321
Chain Sequence
NAIKYLGQDYENLRARCLQNGVLFQDDAFPPVSHSLGFKELGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNETILHRVVPYGQSFQEGYAGIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHSAQGNEFWSALLEKAYAKVNGSYEALSGGCTSEAFEDFTGGVTEWYDLQKAPSDLYQIILKALERGSLLGCSINISDIRDLEAITFKNLVRGHAYSVTDAKQVTYQGQRVNLIRMRNPWGEVEWKGPWSDNSYEWNKVDPYEREQLRVKMEDGEFWMSFRDFIREFTKLEICNL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures of Calpain-E64 and -Leupeptin Inhibitor Complexes Reveal Mobile Loops Gating the Active Site
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Rattus norvegicus
molecule keywords Calpain 1, large [catalytic] subunit
total genus 96
structure length 321
sequence length 321
ec nomenclature ec 3.4.22.52: Calpain-1.
pdb deposition date 2004-06-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00648 Peptidase_C2 Calpain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1tl9A02
1KHQA 4PI3A 4Q8HA 5CHTA 3F75A 1F29A 3KSEA 3USVA 2F7DA 1ZCMA 1QOLA 2OULA 1PADA 2H7JA 2FYEA 3KFQA 4N79A 4CDEB 3N3KA 3QT4A 2FRQA 3OVZA 2DC7A 3OISA 4FJCA 4XUIA 2FT2A 1ITOA 3BCNA 4CDFB 3V6CA 1CV8A 2AIMA 1CB5A 4QBBA 3MORA 1MEGA 1GCBA 1TU6A 2DCDA 2E01A 4QRVA 1U9XA 4ZUXU 3N3GA 3ERVA 1STFE 1DEUA 1BY8A 6PADA 2XU5A 2NQDB 4DMYA 2AYOA 1GMYA 4FK5A 2DJFB 2GHUA 4MZSA 5CHVA 2DC9A 3I3TA 3H6SA 3HHAA 1IWDA 3P5XA 3BWKA 1CTEA 3BPMA 5J94A 2HXZA 2NQGA 3KWBX 2B1NA 3O0UA 1VSNA 3N4CA 1ATKA 2AUZA 1MS6A 2HD5A 4PP1A 1CSBB 5CVNB 3I06A 1SP4B 2NQIA 2CIOA 3S3RA 1NB5A 1U9WA 1U5IA 4PADA 3HWNA 3HHIA 3CH3X 1MHWA 2PADA 1F2AA 4AXLA 1AYWA 4YV8A 3IV2A 1BQIA 1FH0A 4K7CA 1MDWA 3IOQA 1NLJA 3U8EA 2E03A 1EWPA 2E02A 3OF9A 1KXRA 2DZZA 1PE6A 4BQVA 1PPPA 4BPVA 1AECA 1MEMA 1PPNA 1EWMA 1AIMA 1SNKA 2DCBA 3IMAA 2PBHA 1NPZA 1M6DA 1KFUL 3PW3A 2XU3A 4MSXA 5K16A 3RVVA 1YVBA 4N8WA 2P7UA 3H7DA 2DC6A 2VHSA 2B1MA 2C0YA 2YJ9A 1MIRA 3M99A 5CVOB 1AU0A 4AXMA 2DZYA 2XU4A 3P5UA 1F2BA 1YK8A 2DCCA 4KLBA 2G6DA 1AYVA 1TLOA 3HD3A 4OELA 3D6SA 3OVXA 1PPOA 2ACTA 1POPA 1AYUA 2R6NA 3WXGA 2R9MA 4X6HA 1QDQA 4PP2E 1NQCA 2YJ2A 1PPDA 4WA6A 1VJVA 2IBIA 4HWYA 3K24A 1NL6A 4CDDB 4YYRA 1BGOA 5PADA 1A6RA 3P5VA 4G54A 4YYSA 2XU1A 3ZUAA 1BP4A 3IEJA 3TNXA 3WXEA 3OF8A 4P6EA 2PNSA 2FTDA 4YYWA 8PCHA 1JQPA 1CPJA 3V6EA 3RVXA 2OP3A 1ME4A 1O0EA 3P5WA 5JH3A 1EWOA 2FO5A 2AVWA 2ARYA 2YJBA 1CJLA 2AYNA 5F02A 4W5BA 3MHHA 4I05A 3GCBA 4YYUA 2WBFX 2O6XA 3PBHA 2G8EA 3BC3A 2P86A 1AU4A 3K9MA 2R9CA 7PCKA 1PBHA 3BPFA 4OEMA 1CS8A 4YVAA 1PIPA 1U9VA 4BS6A 3QSDA 5JA7A 2P0RA 1ME3A 3KKUA 1U9QX 4MZOA 3LXSA 4YYVA 1KHPA 1KFXL 1QXPA 1YALA 3AI8A 1GECE 1HUCB 3CH2X 9PAPA 3QJ3A 1AU2A 2JQGR 3NHEA 3PDFA 2ATOA 5FPWA 3B79A 3CBKA 1Y4HA 2FRAA 2HH5A 2Y6EA 1TL9A 3WXFA 4Q8GA 3LFYA 4FIPA 4N4ZA 3IUTA 2VHFA 4X6IA 1CQDA 3KWZA 4BS5A 2F1GA 3DF0A 3CBJA 4BSQA 2FUDA 4W5CA 3MHSA 3E1ZB 3O1GA 1QMYA 1DF0A 4W4UA 1YK7A 3F5VA 2YJ8A 1PCIA 3H8CA 3MTNA 4QRXA 1Y08A 1XKGA 3C9EA 1EWLA 3K8UA 4RY2A 3S3QA 1PXVA 2Y5BA 2R9OA 5EF4A 2PREA 3H8BA 2AU1A 4I04A 1THEA 3IHPA 2NQAA 1Q6KA 4CZWA 4YYQA 2R9FA 4P6GA 2JQFR 2DJGB 2G8JA 5A24A 2E00A 1ICFA 4QH6A 2R9NA 4QRGA 1S4VA 4I07A 3H89A 3RVWA 3BOWA 3KW9A 4XR7A 5EGWA 2DC8A 2GFOA 2AUXA 2IPPB 2DCAA 2G7YA 2FQ9A 2AS8A 5CVMA 2HHNA 1GLOA 2BDZA 1K3BB 1X9YA 3PNRA 1NB3A 2BDLA 1AU3A 4DMXA 2CB5A 2YJCA 4X6JA 4CDCB 1F2CA 1YT7A 1CVZA 3KX1A 2OZ2A 1EF7A 1ZIVA
chains in the Genus database with same CATH superfamily
2JRIA 3PRPA 1KHQA 4PI3A 4Q8HA 1YZBA 5CHTA 3F75A 1F29A 3KSEA 3USVA 2F7DA 1ZCMA 1QOLA 2OULA 1PADA 2H7JA 2FYEA 4MI7A 3KFQA 4N79A 4CDEB 3N3KA 5JZEA 3QT4A 2FRQA 3OVZA 2DC7A 3OISA 4FJCA 2BTWB 4XUIA 2FT2A 1ITOA 3BCNA 4CDFB 3V6CA 3C0RA 1CV8A 2AIMA 4XZXA 3RNVA 1CB5A 4QBBA 4IP3A 3W31A 3MORA 1MEGA 1GCBA 1TU6A 2DCDA 2E01A 4QRVA 1U9XA 4ZUXU 3N3GA 3ERVA 1STFE 1DEUA 3IFUA 1BY8A 3PT2A 6PADA 2XU5A 2NQDB 4DMYA 2AYOA 1GMYA 2AGAA 4FK5A 2DJFB 2GHUA 4MZSA 5CHVA 2DC9A 3I3TA 3H6SA 2HWKA 3HHAA 1IWDA 3P5XA 3BWKA 1CTEA 3BPMA 5J94A 2HXZA 2NQGA 3KWBX 2B1NA 1UKFA 3O0UA 1VSNA 3N4CA 1ATKA 2AUZA 1MS6A 2BTWA 2HD5A 4RNAA 4PP1A 1CSBB 5CVNB 3I06A 1SP4B 4A5UA 2NQIA 4IUMA 2CIOA 3S3RA 1NB5A 1U9WA 1U5IA 4PADA 3HWNA 3HHIA 5KO3A 4BOZA 3CH3X 1MHWA 2PADA 1F2AA 4AXLA 1AYWA 4YV8A 3IV2A 1BQIA 1FH0A 4K7CA 1MDWA 3IOQA 1NLJA 4D8IA 4HXDB 3U8EA 2E03A 1EWPA 2E02A 3OF9A 1KXRA 2DZZA 1PE6A 4BOQA 4BQVA 1PPPA 4BPVA 1AECA 1MEMA 1PPNA 1EWMA 3B21A 1AIMA 1SNKA 2DCBA 3IMAA 2PBHA 1NPZA 1M6DA 1KFUL 3PW3A 2XU3A 4MSXA 5K16A 3RVVA 1YVBA 2Z84A 4N8WA 3BY4A 2P7UA 3H7DA 2J7QA 2DC6A 2VHSA 3W30A 2B1MA 4R3DA 2C0YA 2YJ9A 3TMPA 1MIRA 3M99A 5CVOB 1AU0A 4BOPA 4AXMA 2DZYA 4OVZB 2XU4A 3P5UA 4RF1A 1F2BA 1YK8A 2DCCA 4KLBA 2G6DA 1AYVA 1TLOA 3HD3A 4OELA 3D6SA 3OVXA 1PPOA 2ACTA 1POPA 1AYUA 4WURA 2UZJA 3PRMA 2R6NA 3WXGA 2R9MA 4X6HA 1QDQA 4PP2E 3PSEA 5EZQA 1NQCA 2YJ2A 1PPDA 2JTCA 1VJVA 4WA6A 1DKIA 2IBIA 5EZSA 4HWYA 3K24A 1NL6A 4CDDB 4YYRA 1BGOA 5PADA 1A6RA 3P5VA 4G54A 4YYSA 2XU1A 3ZUAA 1BP4A 3IEJA 3TNXA 3WXEA 3OF8A 4P6EA 2PNSA 4OVZA 2FTDA 4YYWA 8PCHA 1JQPA 1CPJA 3V6EA 1PVJA 4REZA 3RVXA 2OP3A 1ME4A 1O0EA 3P5WA 5JH3A 1EWOA 2FO5A 2AVWA 2ARYA 2YJBA 1CJLA 2AYNA 5F02A 4W5BA 3MHHA 4I05A 3GCBA 4YYUA 2WBFX 4P16A 2O6XA 3PBHA 2G8EA 3BC3A 2P86A 1AU4A 3K9MA 2R9CA 7PCKA 1PBHA 3BPFA 4OEMA 1CS8A 2DOSA 4YVAA 3MTVA 1PIPA 1U9VA 4BS6A 3QSDA 5JA7A 2P0RA 1ME3A 3KKUA 1U9QX 4MZOA 3LXSA 4YYVA 1KHPA 1KFXL 1QXPA 4GUAA 1YALA 3AI8A 1GECE 1HUCB 3PHUA 3CH2X 9PAPA 3QJ3A 1AU2A 2JQGR 3NHEA 3PDFA 2ATOA 5FPWA 3B79A 3PHXA 3MJ5A 3CBKA 1Y4HA 4RF0A 5E6JA 2FRAA 2HH5A 2Y6EA 1TL9A 3TRKA 3WXFA 4Q8GA 3LFYA 4FIPA 4N4ZA 3IUTA 2VHFA 4X6IA 1CQDA 3KWZA 4BS5A 2F1GA 3DF0A 3CBJA 4BSQA 4D8BA 2FUDA 3BBAA 4W5CA 3MHSA 3PHWA 3E1ZB 3O1GA 1QMYA 1DF0A 4W4UA 1YK7A 3F5VA 2YJ8A 1PCIA 3H8CA 3MTNA 4QRXA 1Y08A 1XKGA 3C9EA 1EWLA 3K8UA 4RY2A 3BB7A 3S3QA 1PXVA 2FE8A 2Y5BA 2R9OA 4M0WA 5EF4A 2PREA 3H8BA 4OW0A 2AU1A 4I04A 1THEA 3IHPA 4BOSA 2J7QC 2NQAA 1Q6KA 4CZWA 4YYQA 3ZNHA 2R9FA 4P6GA 2JQFR 4MM3B 2DJGB 4PT5A 2G8JA 4ZTBA 5A24A 2E00A 1ICFA 4QH6A 2R9NA 4D8EA 4QRGA 1S4VA 4I07A 3H89A 3RVWA 3BOWA 3KW9A 4XR7A 3MP2A 5EGWA 2DC8A 2GFOA 2AUXA 2IPPB 2DCAA 2G7YA 2FQ9A 2AS8A 5CVMA 2BU3A 2HHNA 1GLOA 2BDZA 1K3BB 1X9YA 3PNRA 1NB3A 4BOUA 2BDLA 3E9SA 1AU3A 4DMXA 4RKXA 2CB5A 3O65A 3OQCA 2YJCA 4X6JA 4CDCB 1F2CA 1YT7A 1CVZA 3KX1A 2OZ2A 1EF7A 1ZIVA
chains in the Genus database with same CATH topology
1KHQA 4PI3A 4Q8HA 5CHTA 3F75A 1F29A 3KSEA 3USVA 2F7DA 1ZCMA 1QOLA 2OULA 1PADA 2H7JA 2FYEA 3KFQA 4N79A 4CDEB 3N3KA 3QT4A 2FRQA 3OVZA 2DC7A 3OISA 4FJCA 4XUIA 2FT2A 1ITOA 3BCNA 4CDFB 3V6CA 1CV8A 2AIMA 1CB5A 4QBBA 3MORA 1MEGA 1GCBA 1TU6A 2DCDA 2E01A 4QRVA 1U9XA 4ZUXU 3N3GA 3ERVA 1STFE 1DEUA 1BY8A 6PADA 2XU5A 2NQDB 4DMYA 2AYOA 1GMYA 4FK5A 2DJFB 2GHUA 4MZSA 5CHVA 1E2TA 2DC9A 3I3TA 3H6SA 3HHAA 1IWDA 3P5XA 3BWKA 3D9WA 1CTEA 3BPMA 5J94A 2HXZA 2NQGA 3KWBX 2B1NA 3O0UA 1W4TA 1W5RA 1VSNA 3N4CA 1ATKA 2AUZA 1MS6A 2HD5A 4PP1A 1CSBB 4BGFA 5CVNB 3I06A 1SP4B 2NQIA 2CIOA 3S3RA 1NB5A 1U9WA 1U5IA 4PADA 3HWNA 3HHIA 3CH3X 1MHWA 2PADA 1F2AA 4AXLA 1AYWA 4YV8A 3IV2A 1BQIA 1FH0A 4K7CA 1MDWA 3IOQA 1NLJA 3U8EA 2E03A 1EWPA 2E02A 3OF9A 1KXRA 2DZZA 1PE6A 4BQVA 1PPPA 4BPVA 1AECA 1MEMA 1PPNA 1EWMA 1AIMA 1SNKA 2DCBA 3IMAA 2PBHA 1NPZA 1M6DA 1KFUL 3PW3A 2XU3A 4MSXA 5K16A 3RVVA 1YVBA 4N8WA 2P7UA 3H7DA 2DC6A 2VHSA 2B1MA 2C0YA 2YJ9A 2BSZA 1MIRA 3M99A 5CVOB 1AU0A 4AXMA 2DZYA 4B55A 2XU4A 3P5UA 1F2BA 1YK8A 2DCCA 4KLBA 2G6DA 1AYVA 1TLOA 4C5PA 3HD3A 4OELA 3D6SA 3OVXA 1PPOA 2ACTA 1POPA 1AYUA 2R6NA 3WXGA 2R9MA 4X6HA 1QDQA 4PP2E 1NQCA 2YJ2A 1PPDA 4WA6A 1VJVA 2IBIA 4HWYA 3K24A 1NL6A 4CDDB 4YYRA 1BGOA 5PADA 1A6RA 3P5VA 4G54A 4YYSA 2XU1A 3ZUAA 1BP4A 3IEJA 3TNXA 3WXEA 3OF8A 4P6EA 2PNSA 2FTDA 4YYWA 8PCHA 1JQPA 1CPJA 3V6EA 3RVXA 2OP3A 1GX3A 1ME4A 1O0EA 3P5WA 5JH3A 1EWOA 2FO5A 2AVWA 2ARYA 2YJBA 1CJLA 2AYNA 2VFBA 5F02A 4W5BA 3MHHA 2VFCA 4I05A 3GCBA 4YYUA 2WBFX 2O6XA 3PBHA 2G8EA 3BC3A 2P86A 1AU4A 3K9MA 2R9CA 7PCKA 1PBHA 3BPFA 4OEMA 1CS8A 4YVAA 1PIPA 1U9VA 4BS6A 3QSDA 5JA7A 2P0RA 1ME3A 3KKUA 1U9QX 4MZOA 3LXSA 4YYVA 1KHPA 1KFXL 1QXPA 1YALA 3AI8A 1GECE 1HUCB 3CH2X 9PAPA 3QJ3A 1AU2A 2JQGR 3NHEA 3PDFA 2ATOA 5FPWA 3B79A 3CBKA 1Y4HA 2FRAA 2HH5A 2Y6EA 1TL9A 3WXFA 4Q8GA 3LFYA 4FIPA 4N4ZA 3IUTA 2VHFA 4X6IA 1CQDA 3KWZA 4BS5A 2F1GA 4NV7A 3DF0A 3CBJA 4BSQA 2FUDA 4W5CA 3MHSA 3E1ZB 3O1GA 1QMYA 1DF0A 4W4UA 3LTWA 1YK7A 3F5VA 2YJ8A 1PCIA 3H8CA 3MTNA 4QRXA 1Y08A 1XKGA 3C9EA 1EWLA 3K8UA 4RY2A 3S3QA 1PXVA 2Y5BA 2R9OA 5EF4A 2PREA 3H8BA 2AU1A 4I04A 1THEA 3IHPA 2NQAA 1Q6KA 4CZWA 4YYQA 2R9FA 4P6GA 2JQFR 2DJGB 2G8JA 5A24A 2E00A 1ICFA 4QH6A 2R9NA 4QRGA 1S4VA 4I07A 3H89A 3RVWA 3BOWA 3KW9A 4XR7A 5EGWA 2DC8A 2GFOA 2AUXA 2IPPB 2DCAA 2G7YA 2FQ9A 2AS8A 5CVMA 2HHNA 1GLOA 2BDZA 1K3BB 1X9YA 3PNRA 1NB3A 2BDLA 4NV8A 1AU3A 4DMXA 2CB5A 4GUZA 2YJCA 4X6JA 4CDCB 1F2CA 1YT7A 1W6FA 1CVZA 3KX1A 2OZ2A 1EF7A 1ZIVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KHQ A;  4PI3 A;  4Q8H A;  5CHT A;  3F75 A;  1F29 A;  3KSE A;  3USV A;  2F7D A;  1ZCM A;  1QOL A;  2OUL A;  1PAD A;  2H7J A;  2FYE A;  3KFQ A;  4N79 A;  4CDE B;  3N3K A;  3QT4 A;  2FRQ A;  3OVZ A;  2DC7 A;  3OIS A;  4FJC A;  4XUI A;  2FT2 A;  1ITO A;  3BCN A;  4CDF B;  3V6C A;  1CV8 A;  2AIM A;  1CB5 A;  4QBB A;  3MOR A;  1MEG A;  1GCB A;  1TU6 A;  2DCD A;  2E01 A;  4QRV A;  1U9X A;  4ZUX U;  3N3G A;  3ERV A;  1STF E;  1DEU A;  1BY8 A;  6PAD A;  2XU5 A;  2NQD B;  4DMY A;  2AYO A;  1GMY A;  4FK5 A;  2DJF B;  2GHU A;  4MZS A;  5CHV A;  2DC9 A;  3I3T A;  3H6S A;  3HHA A;  1IWD A;  3P5X A;  3BWK A;  1CTE A;  3BPM A;  5J94 A;  2HXZ A;  2NQG A;  3KWB X;  2B1N A;  3O0U A;  1VSN A;  3N4C A;  1ATK A;  2AUZ A;  1MS6 A;  2HD5 A;  4PP1 A;  1CSB B;  5CVN B;  3I06 A;  1SP4 B;  2NQI A;  2CIO A;  3S3R A;  1NB5 A;  1U9W A;  1U5I A;  4PAD A;  3HWN A;  3HHI A;  3CH3 X;  1MHW A;  2PAD A;  1F2A A;  4AXL A;  1AYW A;  4YV8 A;  3IV2 A;  1BQI A;  1FH0 A;  4K7C A;  1MDW A;  3IOQ A;  1NLJ A;  3U8E A;  2E03 A;  1EWP A;  2E02 A;  3OF9 A;  1KXR A;  2DZZ A;  1PE6 A;  4BQV A;  1PPP A;  4BPV A;  1AEC A;  1MEM A;  1PPN A;  1EWM A;  1AIM A;  1SNK A;  2DCB A;  3IMA A;  2PBH A;  1NPZ A;  1M6D A;  1KFU L;  3PW3 A;  2XU3 A;  4MSX A;  5K16 A;  3RVV A;  1YVB A;  4N8W A;  2P7U A;  3H7D A;  2DC6 A;  2VHS A;  2B1M A;  2C0Y A;  2YJ9 A;  1MIR A;  3M99 A;  5CVO B;  1AU0 A;  4AXM A;  2DZY A;  2XU4 A;  3P5U A;  1F2B A;  1YK8 A;  2DCC A;  4KLB A;  2G6D A;  1AYV A;  1TLO A;  3HD3 A;  4OEL A;  3D6S A;  3OVX A;  1PPO A;  2ACT A;  1POP A;  1AYU A;  2R6N A;  3WXG A;  2R9M A;  4X6H A;  1QDQ A;  4PP2 E;  1NQC A;  2YJ2 A;  1PPD A;  4WA6 A;  1VJV A;  2IBI A;  4HWY A;  3K24 A;  1NL6 A;  4CDD B;  4YYR A;  1BGO A;  5PAD A;  1A6R A;  3P5V A;  4G54 A;  4YYS A;  2XU1 A;  3ZUA A;  1BP4 A;  3IEJ A;  3TNX A;  3WXE A;  3OF8 A;  4P6E A;  2PNS A;  2FTD A;  4YYW A;  8PCH A;  1JQP A;  1CPJ A;  3V6E A;  3RVX A;  2OP3 A;  1ME4 A;  1O0E A;  3P5W A;  5JH3 A;  1EWO A;  2FO5 A;  2AVW A;  2ARY A;  2YJB A;  1CJL A;  2AYN A;  5F02 A;  4W5B A;  3MHH A;  4I05 A;  3GCB A;  4YYU A;  2WBF X;  2O6X A;  3PBH A;  2G8E A;  3BC3 A;  2P86 A;  1AU4 A;  3K9M A;  2R9C A;  7PCK A;  1PBH A;  3BPF A;  4OEM A;  1CS8 A;  4YVA A;  1PIP A;  1U9V A;  4BS6 A;  3QSD A;  5JA7 A;  2P0R A;  1ME3 A;  3KKU A;  1U9Q X;  4MZO A;  3LXS A;  4YYV A;  1KHP A;  1KFX L;  1QXP A;  1YAL A;  3AI8 A;  1GEC E;  1HUC B;  3CH2 X;  9PAP A;  3QJ3 A;  1AU2 A;  2JQG R;  3NHE A;  3PDF A;  2ATO A;  5FPW A;  3B79 A;  3CBK A;  1Y4H A;  2FRA A;  2HH5 A;  2Y6E A;  1TL9 A;  3WXF A;  4Q8G A;  3LFY A;  4FIP A;  4N4Z A;  3IUT A;  2VHF A;  4X6I A;  1CQD A;  3KWZ A;  4BS5 A;  2F1G A;  3DF0 A;  3CBJ A;  4BSQ A;  2FUD A;  4W5C A;  3MHS A;  3E1Z B;  3O1G A;  1QMY A;  1DF0 A;  4W4U A;  1YK7 A;  3F5V A;  2YJ8 A;  1PCI A;  3H8C A;  3MTN A;  4QRX A;  1Y08 A;  1XKG A;  3C9E A;  1EWL A;  3K8U A;  4RY2 A;  3S3Q A;  1PXV A;  2Y5B A;  2R9O A;  5EF4 A;  2PRE A;  3H8B A;  2AU1 A;  4I04 A;  1THE A;  3IHP A;  2NQA A;  1Q6K A;  4CZW A;  4YYQ A;  2R9F A;  4P6G A;  2JQF R;  2DJG B;  2G8J A;  5A24 A;  2E00 A;  1ICF A;  4QH6 A;  2R9N A;  4QRG A;  1S4V A;  4I07 A;  3H89 A;  3RVW A;  3BOW A;  3KW9 A;  4XR7 A;  5EGW A;  2DC8 A;  2GFO A;  2AUX A;  2IPP B;  2DCA A;  2G7Y A;  2FQ9 A;  2AS8 A;  5CVM A;  2HHN A;  1GLO A;  2BDZ A;  1K3B B;  1X9Y A;  3PNR A;  1NB3 A;  2BDL A;  1AU3 A;  4DMX A;  2CB5 A;  2YJC A;  4X6J A;  4CDC B;  1F2C A;  1YT7 A;  1CVZ A;  3KX1 A;  2OZ2 A;  1EF7 A;  1ZIV A; 
#chains in the Genus database with same CATH topology
 2JRI A;  3PRP A;  1KHQ A;  4PI3 A;  4Q8H A;  1YZB A;  5CHT A;  3F75 A;  1F29 A;  3KSE A;  3USV A;  2F7D A;  1ZCM A;  1QOL A;  2OUL A;  1PAD A;  2H7J A;  2FYE A;  4MI7 A;  3KFQ A;  4N79 A;  4CDE B;  3N3K A;  5JZE A;  3QT4 A;  2FRQ A;  3OVZ A;  2DC7 A;  3OIS A;  4FJC A;  2BTW B;  4XUI A;  2FT2 A;  1ITO A;  3BCN A;  4CDF B;  3V6C A;  3C0R A;  1CV8 A;  2AIM A;  4XZX A;  3RNV A;  1CB5 A;  4QBB A;  4IP3 A;  3W31 A;  3MOR A;  1MEG A;  1GCB A;  1TU6 A;  2DCD A;  2E01 A;  4QRV A;  1U9X A;  4ZUX U;  3N3G A;  3ERV A;  1STF E;  1DEU A;  3IFU A;  1BY8 A;  3PT2 A;  6PAD A;  2XU5 A;  2NQD B;  4DMY A;  2AYO A;  1GMY A;  2AGA A;  4FK5 A;  2DJF B;  2GHU A;  4MZS A;  5CHV A;  2DC9 A;  3I3T A;  3H6S A;  2HWK A;  3HHA A;  1IWD A;  3P5X A;  3BWK A;  1CTE A;  3BPM A;  5J94 A;  2HXZ A;  2NQG A;  3KWB X;  2B1N A;  1UKF A;  3O0U A;  1VSN A;  3N4C A;  1ATK A;  2AUZ A;  1MS6 A;  2BTW A;  2HD5 A;  4RNA A;  4PP1 A;  1CSB B;  5CVN B;  3I06 A;  1SP4 B;  4A5U A;  2NQI A;  4IUM A;  2CIO A;  3S3R A;  1NB5 A;  1U9W A;  1U5I A;  4PAD A;  3HWN A;  3HHI A;  5KO3 A;  4BOZ A;  3CH3 X;  1MHW A;  2PAD A;  1F2A A;  4AXL A;  1AYW A;  4YV8 A;  3IV2 A;  1BQI A;  1FH0 A;  4K7C A;  1MDW A;  3IOQ A;  1NLJ A;  4D8I A;  4HXD B;  3U8E A;  2E03 A;  1EWP A;  2E02 A;  3OF9 A;  1KXR A;  2DZZ A;  1PE6 A;  4BOQ A;  4BQV A;  1PPP A;  4BPV A;  1AEC A;  1MEM A;  1PPN A;  1EWM A;  3B21 A;  1AIM A;  1SNK A;  2DCB A;  3IMA A;  2PBH A;  1NPZ A;  1M6D A;  1KFU L;  3PW3 A;  2XU3 A;  4MSX A;  5K16 A;  3RVV A;  1YVB A;  2Z84 A;  4N8W A;  3BY4 A;  2P7U A;  3H7D A;  2J7Q A;  2DC6 A;  2VHS A;  3W30 A;  2B1M A;  4R3D A;  2C0Y A;  2YJ9 A;  3TMP A;  1MIR A;  3M99 A;  5CVO B;  1AU0 A;  4BOP A;  4AXM A;  2DZY A;  4OVZ B;  2XU4 A;  3P5U A;  4RF1 A;  1F2B A;  1YK8 A;  2DCC A;  4KLB A;  2G6D A;  1AYV A;  1TLO A;  3HD3 A;  4OEL A;  3D6S A;  3OVX A;  1PPO A;  2ACT A;  1POP A;  1AYU A;  4WUR A;  2UZJ A;  3PRM A;  2R6N A;  3WXG A;  2R9M A;  4X6H A;  1QDQ A;  4PP2 E;  3PSE A;  5EZQ A;  1NQC A;  2YJ2 A;  1PPD A;  2JTC A;  1VJV A;  4WA6 A;  1DKI A;  2IBI A;  5EZS A;  4HWY A;  3K24 A;  1NL6 A;  4CDD B;  4YYR A;  1BGO A;  5PAD A;  1A6R A;  3P5V A;  4G54 A;  4YYS A;  2XU1 A;  3ZUA A;  1BP4 A;  3IEJ A;  3TNX A;  3WXE A;  3OF8 A;  4P6E A;  2PNS A;  4OVZ A;  2FTD A;  4YYW A;  8PCH A;  1JQP A;  1CPJ A;  3V6E A;  1PVJ A;  4REZ A;  3RVX A;  2OP3 A;  1ME4 A;  1O0E A;  3P5W A;  5JH3 A;  1EWO A;  2FO5 A;  2AVW A;  2ARY A;  2YJB A;  1CJL A;  2AYN A;  5F02 A;  4W5B A;  3MHH A;  4I05 A;  3GCB A;  4YYU A;  2WBF X;  4P16 A;  2O6X A;  3PBH A;  2G8E A;  3BC3 A;  2P86 A;  1AU4 A;  3K9M A;  2R9C A;  7PCK A;  1PBH A;  3BPF A;  4OEM A;  1CS8 A;  2DOS A;  4YVA A;  3MTV A;  1PIP A;  1U9V A;  4BS6 A;  3QSD A;  5JA7 A;  2P0R A;  1ME3 A;  3KKU A;  1U9Q X;  4MZO A;  3LXS A;  4YYV A;  1KHP A;  1KFX L;  1QXP A;  4GUA A;  1YAL A;  3AI8 A;  1GEC E;  1HUC B;  3PHU A;  3CH2 X;  9PAP A;  3QJ3 A;  1AU2 A;  2JQG R;  3NHE A;  3PDF A;  2ATO A;  5FPW A;  3B79 A;  3PHX A;  3MJ5 A;  3CBK A;  1Y4H A;  4RF0 A;  5E6J A;  2FRA A;  2HH5 A;  2Y6E A;  1TL9 A;  3TRK A;  3WXF A;  4Q8G A;  3LFY A;  4FIP A;  4N4Z A;  3IUT A;  2VHF A;  4X6I A;  1CQD A;  3KWZ A;  4BS5 A;  2F1G A;  3DF0 A;  3CBJ A;  4BSQ A;  4D8B A;  2FUD A;  3BBA A;  4W5C A;  3MHS A;  3PHW A;  3E1Z B;  3O1G A;  1QMY A;  1DF0 A;  4W4U A;  1YK7 A;  3F5V A;  2YJ8 A;  1PCI A;  3H8C A;  3MTN A;  4QRX A;  1Y08 A;  1XKG A;  3C9E A;  1EWL A;  3K8U A;  4RY2 A;  3BB7 A;  3S3Q A;  1PXV A;  2FE8 A;  2Y5B A;  2R9O A;  4M0W A;  5EF4 A;  2PRE A;  3H8B A;  4OW0 A;  2AU1 A;  4I04 A;  1THE A;  3IHP A;  4BOS A;  2J7Q C;  2NQA A;  1Q6K A;  4CZW A;  4YYQ A;  3ZNH A;  2R9F A;  4P6G A;  2JQF R;  4MM3 B;  2DJG B;  4PT5 A;  2G8J A;  4ZTB A;  5A24 A;  2E00 A;  1ICF A;  4QH6 A;  2R9N A;  4D8E A;  4QRG A;  1S4V A;  4I07 A;  3H89 A;  3RVW A;  3BOW A;  3KW9 A;  4XR7 A;  3MP2 A;  5EGW A;  2DC8 A;  2GFO A;  2AUX A;  2IPP B;  2DCA A;  2G7Y A;  2FQ9 A;  2AS8 A;  5CVM A;  2BU3 A;  2HHN A;  1GLO A;  2BDZ A;  1K3B B;  1X9Y A;  3PNR A;  1NB3 A;  4BOU A;  2BDL A;  3E9S A;  1AU3 A;  4DMX A;  4RKX A;  2CB5 A;  3O65 A;  3OQC A;  2YJC A;  4X6J A;  4CDC B;  1F2C A;  1YT7 A;  1CVZ A;  3KX1 A;  2OZ2 A;  1EF7 A;  1ZIV A; 
#chains in the Genus database with same CATH homology
 1KHQ A;  4PI3 A;  4Q8H A;  5CHT A;  3F75 A;  1F29 A;  3KSE A;  3USV A;  2F7D A;  1ZCM A;  1QOL A;  2OUL A;  1PAD A;  2H7J A;  2FYE A;  3KFQ A;  4N79 A;  4CDE B;  3N3K A;  3QT4 A;  2FRQ A;  3OVZ A;  2DC7 A;  3OIS A;  4FJC A;  4XUI A;  2FT2 A;  1ITO A;  3BCN A;  4CDF B;  3V6C A;  1CV8 A;  2AIM A;  1CB5 A;  4QBB A;  3MOR A;  1MEG A;  1GCB A;  1TU6 A;  2DCD A;  2E01 A;  4QRV A;  1U9X A;  4ZUX U;  3N3G A;  3ERV A;  1STF E;  1DEU A;  1BY8 A;  6PAD A;  2XU5 A;  2NQD B;  4DMY A;  2AYO A;  1GMY A;  4FK5 A;  2DJF B;  2GHU A;  4MZS A;  5CHV A;  1E2T A;  2DC9 A;  3I3T A;  3H6S A;  3HHA A;  1IWD A;  3P5X A;  3BWK A;  3D9W A;  1CTE A;  3BPM A;  5J94 A;  2HXZ A;  2NQG A;  3KWB X;  2B1N A;  3O0U A;  1W4T A;  1W5R A;  1VSN A;  3N4C A;  1ATK A;  2AUZ A;  1MS6 A;  2HD5 A;  4PP1 A;  1CSB B;  4BGF A;  5CVN B;  3I06 A;  1SP4 B;  2NQI A;  2CIO A;  3S3R A;  1NB5 A;  1U9W A;  1U5I A;  4PAD A;  3HWN A;  3HHI A;  3CH3 X;  1MHW A;  2PAD A;  1F2A A;  4AXL A;  1AYW A;  4YV8 A;  3IV2 A;  1BQI A;  1FH0 A;  4K7C A;  1MDW A;  3IOQ A;  1NLJ A;  3U8E A;  2E03 A;  1EWP A;  2E02 A;  3OF9 A;  1KXR A;  2DZZ A;  1PE6 A;  4BQV A;  1PPP A;  4BPV A;  1AEC A;  1MEM A;  1PPN A;  1EWM A;  1AIM A;  1SNK A;  2DCB A;  3IMA A;  2PBH A;  1NPZ A;  1M6D A;  1KFU L;  3PW3 A;  2XU3 A;  4MSX A;  5K16 A;  3RVV A;  1YVB A;  4N8W A;  2P7U A;  3H7D A;  2DC6 A;  2VHS A;  2B1M A;  2C0Y A;  2YJ9 A;  2BSZ A;  1MIR A;  3M99 A;  5CVO B;  1AU0 A;  4AXM A;  2DZY A;  4B55 A;  2XU4 A;  3P5U A;  1F2B A;  1YK8 A;  2DCC A;  4KLB A;  2G6D A;  1AYV A;  1TLO A;  4C5P A;  3HD3 A;  4OEL A;  3D6S A;  3OVX A;  1PPO A;  2ACT A;  1POP A;  1AYU A;  2R6N A;  3WXG A;  2R9M A;  4X6H A;  1QDQ A;  4PP2 E;  1NQC A;  2YJ2 A;  1PPD A;  4WA6 A;  1VJV A;  2IBI A;  4HWY A;  3K24 A;  1NL6 A;  4CDD B;  4YYR A;  1BGO A;  5PAD A;  1A6R A;  3P5V A;  4G54 A;  4YYS A;  2XU1 A;  3ZUA A;  1BP4 A;  3IEJ A;  3TNX A;  3WXE A;  3OF8 A;  4P6E A;  2PNS A;  2FTD A;  4YYW A;  8PCH A;  1JQP A;  1CPJ A;  3V6E A;  3RVX A;  2OP3 A;  1GX3 A;  1ME4 A;  1O0E A;  3P5W A;  5JH3 A;  1EWO A;  2FO5 A;  2AVW A;  2ARY A;  2YJB A;  1CJL A;  2AYN A;  2VFB A;  5F02 A;  4W5B A;  3MHH A;  2VFC A;  4I05 A;  3GCB A;  4YYU A;  2WBF X;  2O6X A;  3PBH A;  2G8E A;  3BC3 A;  2P86 A;  1AU4 A;  3K9M A;  2R9C A;  7PCK A;  1PBH A;  3BPF A;  4OEM A;  1CS8 A;  4YVA A;  1PIP A;  1U9V A;  4BS6 A;  3QSD A;  5JA7 A;  2P0R A;  1ME3 A;  3KKU A;  1U9Q X;  4MZO A;  3LXS A;  4YYV A;  1KHP A;  1KFX L;  1QXP A;  1YAL A;  3AI8 A;  1GEC E;  1HUC B;  3CH2 X;  9PAP A;  3QJ3 A;  1AU2 A;  2JQG R;  3NHE A;  3PDF A;  2ATO A;  5FPW A;  3B79 A;  3CBK A;  1Y4H A;  2FRA A;  2HH5 A;  2Y6E A;  1TL9 A;  3WXF A;  4Q8G A;  3LFY A;  4FIP A;  4N4Z A;  3IUT A;  2VHF A;  4X6I A;  1CQD A;  3KWZ A;  4BS5 A;  2F1G A;  4NV7 A;  3DF0 A;  3CBJ A;  4BSQ A;  2FUD A;  4W5C A;  3MHS A;  3E1Z B;  3O1G A;  1QMY A;  1DF0 A;  4W4U A;  3LTW A;  1YK7 A;  3F5V A;  2YJ8 A;  1PCI A;  3H8C A;  3MTN A;  4QRX A;  1Y08 A;  1XKG A;  3C9E A;  1EWL A;  3K8U A;  4RY2 A;  3S3Q A;  1PXV A;  2Y5B A;  2R9O A;  5EF4 A;  2PRE A;  3H8B A;  2AU1 A;  4I04 A;  1THE A;  3IHP A;  2NQA A;  1Q6K A;  4CZW A;  4YYQ A;  2R9F A;  4P6G A;  2JQF R;  2DJG B;  2G8J A;  5A24 A;  2E00 A;  1ICF A;  4QH6 A;  2R9N A;  4QRG A;  1S4V A;  4I07 A;  3H89 A;  3RVW A;  3BOW A;  3KW9 A;  4XR7 A;  5EGW A;  2DC8 A;  2GFO A;  2AUX A;  2IPP B;  2DCA A;  2G7Y A;  2FQ9 A;  2AS8 A;  5CVM A;  2HHN A;  1GLO A;  2BDZ A;  1K3B B;  1X9Y A;  3PNR A;  1NB3 A;  2BDL A;  4NV8 A;  1AU3 A;  4DMX A;  2CB5 A;  4GUZ A;  2YJC A;  4X6J A;  4CDC B;  1F2C A;  1YT7 A;  1W6F A;  1CVZ A;  3KX1 A;  2OZ2 A;  1EF7 A;  1ZIV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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