1U9WA

Crystal structure of the cysteine protease human cathepsin k in complex with the covalent inhibitor nvp-abi491
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
216
structure length
216
Chain Sequence
RAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Novel purine nitrile derived inhibitors of the cysteine protease cathepsin K
pubmed doi rcsb
molecule keywords Cathepsin K
molecule tags Hydrolase
source organism Homo sapiens
total genus 61
structure length 216
sequence length 216
ec nomenclature ec 3.4.22.38: Cathepsin K.
pdb deposition date 2004-08-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1u9wA00
2OZ2A 1YALA 2NQDB 1KXRA 2DJGB 2ACTA 1ME4A 2C0YA 2AVWA 1HUCB 4X6HA 1CTEA 1NLJA 4W5BA 5A24A 3CBJA 3KWBX 4N8WA 2FQ9A 4P6GA 3IOQA 1Q6KA 1U9QX 3OISA 2DC6A 3TNXA 2YJBA 1AU4A 5CHTA 3ERVA 1CPJA 1EWPA 2DZYA 1NPZA 1TU6A 2P7UA 1KFXL 4AXMA 2YJ2A 4QRXA 3PDFA 1NB5A 3LXSA 9PAPA 3RVWA 1PPPA 2CIOA 4MZSA 1AIMA 5F02A 3M99A 3HHAA 3USVA 2OP3A 3P5VA 3BWKA 1NQCA 3K9MA 3H8BA 1YK7A 1VSNA 4YYVA 1ICFA 3KSEA 1QMYA 3CH3X 3MHSA 2R9OA 1POPA 2DC9A 1MEGA 5FPWA 3V6CA 2NQGA 1F2BA 5J94A 4QBBA 3HD3A 1MS6A 1GMYA 1O0EA 2GFOA 4BS6A 2O6XA 4WA6A 5CVOB 2ATOA 2BDZA 3V6EA 1BY8A 2DCAA 1CJLA 3WXGA 3IHPA 2NQIA 4HWYA 1GLOA 4PI3A 1PCIA 2HXZA 2G8JA 2Y6EA 2F7DA 3BPMA 3IUTA 3H8CA 2YJ8A 2PNSA 4QH6A 4BSQA 2DCDA 3QJ3A 4N79A 1AU2A 4XUIA 2PREA 2VHSA 2PBHA 4ZUXU 1MIRA 3U8EA 2R9MA 1PPDA 1U9XA 2JQFR 1M6DA 1YK8A 1ZCMA 2P86A 4FK5A 1CSBB 4I07A 2AYOA 5K16A 3IV2A 1EWLA 4CZWA 3I3TA 5JA7A 4YV8A 8PCHA 1S4VA 2FYEA 4OELA 1QDQA 2F1GA 4PADA 6PADA 1PXVA 7PCKA 4N4ZA 2E03A 1GCBA 2XU5A 3F75A 1AU3A 3E1ZB 4X6JA 4RY2A 1EWOA 1ZIVA 4Q8HA 4OEMA 2E02A 3DF0A 3BCNA 3PNRA 2YJCA 3AI8A 2GHUA 4G54A 2G8EA 3QT4A 1YVBA 4YYRA 4CDDB 4W5CA 2DJFB 1Y08A 4QRVA 1PIPA 2FO5A 1AU0A 1SNKA 3P5UA 1STFE 2WBFX 3OVXA 3LFYA 2B1NA 3OF9A 4DMYA 2R6NA 3QSDA 4BQVA 2G6DA 3RVVA 1CV8A 1IWDA 3IEJA 4I04A 1F29A 5CVNB 2FRAA 2AU1A 5JH3A 5PADA 4BPVA 1AYUA 2DC8A 2XU4A 1AYWA 3BOWA 1NL6A 2JQGR 4CDEB 1F2AA 2ARYA 3KW9A 2AIMA 2AS8A 3IMAA 2FRQA 3ZUAA 1PBHA 2Y5BA 4YYQA 2OULA 3N4CA 1PPOA 2VHFA 4DMXA 1MDWA 1CQDA 1MEMA 2HHNA 3KFQA 3MORA 4XR7A 4BS5A 1QOLA 1VJVA 4YYUA 3WXEA 4P6EA 4CDCB 1Y4HA 2IPPB 2E00A 1ME3A 1NB3A 1BP4A 2E01A 4FIPA 1AECA 3GCBA 3PBHA 2CB5A 2R9FA 3O1GA 2G7YA 1ITOA 1SP4B 3H89A 1MHWA 1CVZA 2FTDA 1GECE 3P5WA 2IBIA 1FH0A 2P0RA 1KFUL 1F2CA 3B79A 3C9EA 3BC3A 1EF7A 4PP1A 2DZZA 4QRGA 3CBKA 3N3KA 2AYNA 3WXFA 4FJCA 3D6SA 3S3QA 5CHVA 1PE6A 1U9WA 1BQIA 3MTNA 3KX1A 1A6RA 1K3BB 4YVAA 2AUXA 3KWZA 4CDFB 3CH2X 4YYWA 2AUZA 2YJ9A 2BDLA 3S3RA 2XU3A 2PADA 3OF8A 3BPFA 3K8UA 5EF4A 4I05A 2FT2A 3P5XA 1PADA 2NQAA 3F5VA 4YYSA 1KHQA 5EGWA 1U5IA 4KLBA 1BGOA 3N3GA 1TLOA 1AYVA 3OVZA 4MSXA 1THEA 3I06A 2DC7A 1CB5A 4AXLA 2HH5A 4Q8GA 4PP2E 3MHHA 1X9YA 2HD5A 1TL9A 2H7JA 5CVMA 1DEUA 1JQPA 1PPNA 2DCBA 1QXPA 2DCCA 1CS8A 3RVXA 1KHPA 4W4UA 1XKGA 1ATKA 2XU1A 2B1MA 4X6IA 3O0UA 1EWMA 1U9VA 3PW3A 3H6SA 1DF0A 4K7CA 3HWNA 3K24A 2R9NA 2FUDA 4MZOA 1YT7A 3H7DA 3NHEA 2R9CA 3KKUA 3HHIA
chains in the Genus database with same CATH superfamily
3MJ5A 2OZ2A 1YALA 2DOSA 2NQDB 5EZQA 1KXRA 2DJGB 4PT5A 2ACTA 1ME4A 2C0YA 2AVWA 1HUCB 4X6HA 1CTEA 3W31A 1NLJA 4W5BA 5A24A 3CBJA 3KWBX 4N8WA 2FQ9A 4P6GA 3IOQA 1Q6KA 1U9QX 3OISA 2DC6A 3TNXA 2YJBA 1AU4A 4GUAA 5CHTA 3ERVA 1CPJA 5E6JA 1EWPA 2DZYA 4A5UA 4P16A 4IP3A 3PHWA 1NPZA 1TU6A 2P7UA 1KFXL 4AXMA 3W30A 2YJ2A 4QRXA 4WURA 3IFUA 3PHXA 4RKXA 3PDFA 1NB5A 3LXSA 9PAPA 3RVWA 1PPPA 2CIOA 4MZSA 1AIMA 3BY4A 4BOPA 5F02A 3M99A 3HHAA 3USVA 2OP3A 3TRKA 3P5VA 3BWKA 1NQCA 3K9MA 3H8BA 1YK7A 1VSNA 4YYVA 1UKFA 1ICFA 3KSEA 1QMYA 3CH3X 3MHSA 2R9OA 1POPA 2DC9A 1PVJA 1MEGA 5FPWA 3V6CA 2NQGA 1F2BA 5J94A 4QBBA 3HD3A 2J7QC 1MS6A 1GMYA 1O0EA 2FE8A 2GFOA 4BS6A 2O6XA 4WA6A 5CVOB 2ATOA 2BDZA 3V6EA 1BY8A 3BB7A 2DCAA 1CJLA 3WXGA 3IHPA 2NQIA 4HWYA 4D8BA 1GLOA 4PI3A 1PCIA 2HXZA 2G8JA 4RF0A 3RNVA 2Y6EA 3PHUA 2F7DA 2BTWA 3BPMA 2AGAA 3IUTA 3H8CA 2YJ8A 2HWKA 2PNSA 4QH6A 4BSQA 2DCDA 3QJ3A 4D8EA 4N79A 1AU2A 4XUIA 2PREA 2VHSA 3PRMA 2PBHA 4ZUXU 1MIRA 3U8EA 2R9MA 1PPDA 1U9XA 2JQFR 1M6DA 1YK8A 1ZCMA 2P86A 4FK5A 4XZXA 1CSBB 4I07A 2AYOA 3PRPA 5K16A 3IV2A 1DKIA 2BU3A 4IUMA 1EWLA 2BTWB 4CZWA 3I3TA 5JA7A 4YV8A 8PCHA 1S4VA 2FYEA 4OELA 1QDQA 2F1GA 4PADA 6PADA 1PXVA 7PCKA 4OVZA 4R3DA 4D8IA 4N4ZA 2E03A 1GCBA 2XU5A 3F75A 1AU3A 3E1ZB 4HXDB 4X6JA 4RY2A 1EWOA 1ZIVA 4Q8HA 3OQCA 4OEMA 2E02A 3DF0A 3BCNA 3PNRA 2YJCA 3AI8A 4RF1A 5EZSA 2GHUA 4G54A 2G8EA 3QT4A 1YVBA 4YYRA 4CDDB 4W5CA 2DJFB 1Y08A 4QRVA 4BOZA 1PIPA 2FO5A 1AU0A 1SNKA 3P5UA 1STFE 2WBFX 3C0RA 3OVXA 4OVZB 3LFYA 2B1NA 3OF9A 4DMYA 2R6NA 3QSDA 4BQVA 2G6DA 3RVVA 4ZTBA 1CV8A 1IWDA 3IEJA 4I04A 1F29A 5CVNB 2FRAA 2AU1A 5JH3A 5PADA 4BPVA 1AYUA 2DC8A 2XU4A 3MTVA 1AYWA 3BOWA 1NL6A 2JQGR 2Z84A 4CDEB 1F2AA 2ARYA 3KW9A 2AIMA 2AS8A 3IMAA 2FRQA 3ZUAA 1PBHA 2Y5BA 4YYQA 2OULA 3N4CA 2JRIA 1PPOA 2VHFA 4DMXA 1MDWA 4M0WA 1CQDA 1MEMA 2JTCA 2HHNA 4MI7A 3KFQA 3MORA 4XR7A 2J7QA 4BS5A 1QOLA 2UZJA 1VJVA 4YYUA 3WXEA 4P6EA 4CDCB 1Y4HA 2IPPB 2E00A 1ME3A 1NB3A 1BP4A 2E01A 4FIPA 1AECA 3GCBA 3PBHA 2CB5A 2R9FA 3O1GA 2G7YA 1ITOA 1SP4B 3H89A 1MHWA 3E9SA 1CVZA 2FTDA 1GECE 3P5WA 2IBIA 1FH0A 2P0RA 1KFUL 1F2CA 3B79A 3C9EA 3BC3A 1EF7A 4PP1A 2DZZA 4QRGA 3CBKA 3N3KA 2AYNA 3PSEA 3WXFA 4FJCA 3D6SA 3S3QA 5CHVA 1PE6A 4REZA 1U9WA 1BQIA 3MTNA 3KX1A 1A6RA 1K3BB 4YVAA 2AUXA 3KWZA 4CDFB 3CH2X 4YYWA 2AUZA 2YJ9A 2BDLA 3S3RA 2XU3A 2PADA 3B21A 3OF8A 3BPFA 3K8UA 5EF4A 4I05A 2FT2A 3P5XA 3MP2A 1PADA 2NQAA 4OW0A 5KO3A 3F5VA 4YYSA 1KHQA 5EGWA 3O65A 1U5IA 4KLBA 1BGOA 3N3GA 1TLOA 4BOUA 4MM3B 1AYVA 4BOSA 3OVZA 4MSXA 1THEA 3PT2A 3I06A 4BOQA 2DC7A 1CB5A 4AXLA 2HH5A 4Q8GA 4PP2E 3MHHA 1X9YA 2HD5A 1TL9A 2H7JA 5CVMA 4RNAA 1DEUA 1JQPA 1PPNA 2DCBA 1YZBA 1QXPA 3BBAA 2DCCA 1CS8A 3RVXA 1KHPA 4W4UA 1XKGA 1ATKA 3ZNHA 2XU1A 2B1MA 4X6IA 3O0UA 1EWMA 1U9VA 5JZEA 3PW3A 3H6SA 1DF0A 4K7CA 3HWNA 3K24A 2R9NA 2FUDA 4MZOA 1YT7A 3H7DA 3NHEA 2R9CA 3KKUA 3HHIA 3TMPA
chains in the Genus database with same CATH topology
2OZ2A 1YALA 2NQDB 1KXRA 2DJGB 2ACTA 1ME4A 2C0YA 2AVWA 1HUCB 4X6HA 1CTEA 1NLJA 4W5BA 5A24A 3CBJA 3KWBX 4N8WA 2FQ9A 4P6GA 3IOQA 1Q6KA 1U9QX 3OISA 2DC6A 3TNXA 2YJBA 1AU4A 5CHTA 3ERVA 1CPJA 1EWPA 2DZYA 1NPZA 1TU6A 2P7UA 1KFXL 4AXMA 2YJ2A 4QRXA 3PDFA 1NB5A 3LXSA 9PAPA 3RVWA 1PPPA 2CIOA 4MZSA 1AIMA 5F02A 3M99A 3HHAA 3USVA 3D9WA 2OP3A 3P5VA 3BWKA 1NQCA 3K9MA 3H8BA 1YK7A 1VSNA 4YYVA 1ICFA 3KSEA 1QMYA 3CH3X 3MHSA 4NV8A 2R9OA 1POPA 2DC9A 1MEGA 5FPWA 3V6CA 2NQGA 1F2BA 5J94A 4QBBA 3HD3A 1MS6A 1GMYA 1O0EA 2GFOA 4BS6A 2O6XA 4WA6A 5CVOB 2ATOA 2BDZA 3V6EA 2BSZA 1BY8A 1E2TA 2DCAA 1CJLA 3WXGA 3IHPA 2NQIA 4HWYA 1GLOA 4PI3A 1PCIA 2HXZA 2G8JA 2Y6EA 2F7DA 3BPMA 3IUTA 3H8CA 2YJ8A 2PNSA 4QH6A 1W4TA 4BSQA 2DCDA 3QJ3A 4N79A 1AU2A 4XUIA 2PREA 2VHSA 2PBHA 4ZUXU 1MIRA 3U8EA 2R9MA 1PPDA 1U9XA 2JQFR 1M6DA 1YK8A 1ZCMA 2P86A 4FK5A 1CSBB 1W5RA 4I07A 2AYOA 5K16A 3IV2A 1EWLA 4CZWA 3I3TA 5JA7A 4YV8A 8PCHA 1S4VA 2FYEA 4OELA 1QDQA 2F1GA 4PADA 6PADA 1PXVA 7PCKA 4N4ZA 2E03A 1GCBA 2XU5A 3F75A 1AU3A 3E1ZB 4X6JA 4RY2A 1EWOA 1ZIVA 4Q8HA 4OEMA 2E02A 3DF0A 3BCNA 3PNRA 2YJCA 3AI8A 2GHUA 4G54A 2G8EA 3QT4A 1YVBA 4YYRA 4CDDB 4W5CA 2DJFB 1Y08A 2VFBA 4QRVA 1PIPA 2FO5A 1AU0A 1SNKA 3P5UA 1STFE 2WBFX 3OVXA 3LFYA 2B1NA 3OF9A 4DMYA 2R6NA 3QSDA 4BQVA 2G6DA 3RVVA 1CV8A 1IWDA 3IEJA 4I04A 1F29A 5CVNB 2FRAA 2AU1A 5JH3A 2VFCA 5PADA 1AYUA 2DC8A 2XU4A 4BPVA 1AYWA 3BOWA 1NL6A 2JQGR 4CDEB 1F2AA 2ARYA 3KW9A 2AIMA 2AS8A 3IMAA 2FRQA 3ZUAA 1PBHA 2Y5BA 4YYQA 2OULA 3N4CA 1PPOA 2VHFA 4DMXA 1MDWA 1CQDA 1MEMA 2HHNA 3KFQA 3MORA 4XR7A 4BS5A 1QOLA 1VJVA 4YYUA 3WXEA 4P6EA 4CDCB 1Y4HA 2IPPB 2E00A 1ME3A 1NB3A 1BP4A 2E01A 4FIPA 4B55A 1AECA 3GCBA 3PBHA 2CB5A 3LTWA 2R9FA 3O1GA 2G7YA 1ITOA 1SP4B 3H89A 1MHWA 1CVZA 2FTDA 1GECE 3P5WA 2IBIA 1FH0A 2P0RA 1KFUL 1F2CA 3B79A 3C9EA 3BC3A 1EF7A 4PP1A 4GUZA 2DZZA 4QRGA 3CBKA 3N3KA 2AYNA 3WXFA 4FJCA 3D6SA 3S3QA 5CHVA 1PE6A 1U9WA 1BQIA 3MTNA 3KX1A 1A6RA 1K3BB 4YVAA 2AUXA 3KWZA 4CDFB 3CH2X 4YYWA 2AUZA 2YJ9A 2BDLA 3S3RA 2XU3A 2PADA 3OF8A 3BPFA 3K8UA 5EF4A 4I05A 2FT2A 3P5XA 1PADA 2NQAA 3F5VA 4YYSA 1KHQA 4C5PA 5EGWA 1U5IA 4KLBA 1BGOA 3N3GA 1TLOA 4NV7A 1AYVA 3OVZA 4BGFA 4MSXA 1THEA 3I06A 2DC7A 1CB5A 4AXLA 2HH5A 4Q8GA 4PP2E 3MHHA 1GX3A 1X9YA 2HD5A 1TL9A 2H7JA 5CVMA 1DEUA 1JQPA 1PPNA 2DCBA 1QXPA 2DCCA 1CS8A 3RVXA 1KHPA 4W4UA 1XKGA 1ATKA 2XU1A 2B1MA 4X6IA 3O0UA 1EWMA 1U9VA 3PW3A 3H6SA 1DF0A 4K7CA 3HWNA 3K24A 1W6FA 2R9NA 2FUDA 4MZOA 1YT7A 3H7DA 3NHEA 2R9CA 3KKUA 3HHIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OZ2 A;  1YAL A;  2NQD B;  1KXR A;  2DJG B;  2ACT A;  1ME4 A;  2C0Y A;  2AVW A;  1HUC B;  4X6H A;  1CTE A;  1NLJ A;  4W5B A;  5A24 A;  3CBJ A;  3KWB X;  4N8W A;  2FQ9 A;  4P6G A;  3IOQ A;  1Q6K A;  1U9Q X;  3OIS A;  2DC6 A;  3TNX A;  2YJB A;  1AU4 A;  5CHT A;  3ERV A;  1CPJ A;  1EWP A;  2DZY A;  1NPZ A;  1TU6 A;  2P7U A;  1KFX L;  4AXM A;  2YJ2 A;  4QRX A;  3PDF A;  1NB5 A;  3LXS A;  9PAP A;  3RVW A;  1PPP A;  2CIO A;  4MZS A;  1AIM A;  5F02 A;  3M99 A;  3HHA A;  3USV A;  2OP3 A;  3P5V A;  3BWK A;  1NQC A;  3K9M A;  3H8B A;  1YK7 A;  1VSN A;  4YYV A;  1ICF A;  3KSE A;  1QMY A;  3CH3 X;  3MHS A;  2R9O A;  1POP A;  2DC9 A;  1MEG A;  5FPW A;  3V6C A;  2NQG A;  1F2B A;  5J94 A;  4QBB A;  3HD3 A;  1MS6 A;  1GMY A;  1O0E A;  2GFO A;  4BS6 A;  2O6X A;  4WA6 A;  5CVO B;  2ATO A;  2BDZ A;  3V6E A;  1BY8 A;  2DCA A;  1CJL A;  3WXG A;  3IHP A;  2NQI A;  4HWY A;  1GLO A;  4PI3 A;  1PCI A;  2HXZ A;  2G8J A;  2Y6E A;  2F7D A;  3BPM A;  3IUT A;  3H8C A;  2YJ8 A;  2PNS A;  4QH6 A;  4BSQ A;  2DCD A;  3QJ3 A;  4N79 A;  1AU2 A;  4XUI A;  2PRE A;  2VHS A;  2PBH A;  4ZUX U;  1MIR A;  3U8E A;  2R9M A;  1PPD A;  1U9X A;  2JQF R;  1M6D A;  1YK8 A;  1ZCM A;  2P86 A;  4FK5 A;  1CSB B;  4I07 A;  2AYO A;  5K16 A;  3IV2 A;  1EWL A;  4CZW A;  3I3T A;  5JA7 A;  4YV8 A;  8PCH A;  1S4V A;  2FYE A;  4OEL A;  1QDQ A;  2F1G A;  4PAD A;  6PAD A;  1PXV A;  7PCK A;  4N4Z A;  2E03 A;  1GCB A;  2XU5 A;  3F75 A;  1AU3 A;  3E1Z B;  4X6J A;  4RY2 A;  1EWO A;  1ZIV A;  4Q8H A;  4OEM A;  2E02 A;  3DF0 A;  3BCN A;  3PNR A;  2YJC A;  3AI8 A;  2GHU A;  4G54 A;  2G8E A;  3QT4 A;  1YVB A;  4YYR A;  4CDD B;  4W5C A;  2DJF B;  1Y08 A;  4QRV A;  1PIP A;  2FO5 A;  1AU0 A;  1SNK A;  3P5U A;  1STF E;  2WBF X;  3OVX A;  3LFY A;  2B1N A;  3OF9 A;  4DMY A;  2R6N A;  3QSD A;  4BQV A;  2G6D A;  3RVV A;  1CV8 A;  1IWD A;  3IEJ A;  4I04 A;  1F29 A;  5CVN B;  2FRA A;  2AU1 A;  5JH3 A;  5PAD A;  4BPV A;  1AYU A;  2DC8 A;  2XU4 A;  1AYW A;  3BOW A;  1NL6 A;  2JQG R;  4CDE B;  1F2A A;  2ARY A;  3KW9 A;  2AIM A;  2AS8 A;  3IMA A;  2FRQ A;  3ZUA A;  1PBH A;  2Y5B A;  4YYQ A;  2OUL A;  3N4C A;  1PPO A;  2VHF A;  4DMX A;  1MDW A;  1CQD A;  1MEM A;  2HHN A;  3KFQ A;  3MOR A;  4XR7 A;  4BS5 A;  1QOL A;  1VJV A;  4YYU A;  3WXE A;  4P6E A;  4CDC B;  1Y4H A;  2IPP B;  2E00 A;  1ME3 A;  1NB3 A;  1BP4 A;  2E01 A;  4FIP A;  1AEC A;  3GCB A;  3PBH A;  2CB5 A;  2R9F A;  3O1G A;  2G7Y A;  1ITO A;  1SP4 B;  3H89 A;  1MHW A;  1CVZ A;  2FTD A;  1GEC E;  3P5W A;  2IBI A;  1FH0 A;  2P0R A;  1KFU L;  1F2C A;  3B79 A;  3C9E A;  3BC3 A;  1EF7 A;  4PP1 A;  2DZZ A;  4QRG A;  3CBK A;  3N3K A;  2AYN A;  3WXF A;  4FJC A;  3D6S A;  3S3Q A;  5CHV A;  1PE6 A;  1U9W A;  1BQI A;  3MTN A;  3KX1 A;  1A6R A;  1K3B B;  4YVA A;  2AUX A;  3KWZ A;  4CDF B;  3CH2 X;  4YYW A;  2AUZ A;  2YJ9 A;  2BDL A;  3S3R A;  2XU3 A;  2PAD A;  3OF8 A;  3BPF A;  3K8U A;  5EF4 A;  4I05 A;  2FT2 A;  3P5X A;  1PAD A;  2NQA A;  3F5V A;  4YYS A;  1KHQ A;  5EGW A;  1U5I A;  4KLB A;  1BGO A;  3N3G A;  1TLO A;  1AYV A;  3OVZ A;  4MSX A;  1THE A;  3I06 A;  2DC7 A;  1CB5 A;  4AXL A;  2HH5 A;  4Q8G A;  4PP2 E;  3MHH A;  1X9Y A;  2HD5 A;  1TL9 A;  2H7J A;  5CVM A;  1DEU A;  1JQP A;  1PPN A;  2DCB A;  1QXP A;  2DCC A;  1CS8 A;  3RVX A;  1KHP A;  4W4U A;  1XKG A;  1ATK A;  2XU1 A;  2B1M A;  4X6I A;  3O0U A;  1EWM A;  1U9V A;  3PW3 A;  3H6S A;  1DF0 A;  4K7C A;  3HWN A;  3K24 A;  2R9N A;  2FUD A;  4MZO A;  1YT7 A;  3H7D A;  3NHE A;  2R9C A;  3KKU A;  3HHI A; 
#chains in the Genus database with same CATH topology
 3MJ5 A;  2OZ2 A;  1YAL A;  2DOS A;  2NQD B;  5EZQ A;  1KXR A;  2DJG B;  4PT5 A;  2ACT A;  1ME4 A;  2C0Y A;  2AVW A;  1HUC B;  4X6H A;  1CTE A;  3W31 A;  1NLJ A;  4W5B A;  5A24 A;  3CBJ A;  3KWB X;  4N8W A;  2FQ9 A;  4P6G A;  3IOQ A;  1Q6K A;  1U9Q X;  3OIS A;  2DC6 A;  3TNX A;  2YJB A;  1AU4 A;  4GUA A;  5CHT A;  3ERV A;  1CPJ A;  5E6J A;  1EWP A;  2DZY A;  4A5U A;  4P16 A;  4IP3 A;  3PHW A;  1NPZ A;  1TU6 A;  2P7U A;  1KFX L;  4AXM A;  3W30 A;  2YJ2 A;  4QRX A;  4WUR A;  3IFU A;  3PHX A;  4RKX A;  3PDF A;  1NB5 A;  3LXS A;  9PAP A;  3RVW A;  1PPP A;  2CIO A;  4MZS A;  1AIM A;  3BY4 A;  4BOP A;  5F02 A;  3M99 A;  3HHA A;  3USV A;  2OP3 A;  3TRK A;  3P5V A;  3BWK A;  1NQC A;  3K9M A;  3H8B A;  1YK7 A;  1VSN A;  4YYV A;  1UKF A;  1ICF A;  3KSE A;  1QMY A;  3CH3 X;  3MHS A;  2R9O A;  1POP A;  2DC9 A;  1PVJ A;  1MEG A;  5FPW A;  3V6C A;  2NQG A;  1F2B A;  5J94 A;  4QBB A;  3HD3 A;  2J7Q C;  1MS6 A;  1GMY A;  1O0E A;  2FE8 A;  2GFO A;  4BS6 A;  2O6X A;  4WA6 A;  5CVO B;  2ATO A;  2BDZ A;  3V6E A;  1BY8 A;  3BB7 A;  2DCA A;  1CJL A;  3WXG A;  3IHP A;  2NQI A;  4HWY A;  4D8B A;  1GLO A;  4PI3 A;  1PCI A;  2HXZ A;  2G8J A;  4RF0 A;  3RNV A;  2Y6E A;  3PHU A;  2F7D A;  2BTW A;  3BPM A;  2AGA A;  3IUT A;  3H8C A;  2YJ8 A;  2HWK A;  2PNS A;  4QH6 A;  4BSQ A;  2DCD A;  3QJ3 A;  4D8E A;  4N79 A;  1AU2 A;  4XUI A;  2PRE A;  2VHS A;  3PRM A;  2PBH A;  4ZUX U;  1MIR A;  3U8E A;  2R9M A;  1PPD A;  1U9X A;  2JQF R;  1M6D A;  1YK8 A;  1ZCM A;  2P86 A;  4FK5 A;  4XZX A;  1CSB B;  4I07 A;  2AYO A;  3PRP A;  5K16 A;  3IV2 A;  1DKI A;  2BU3 A;  4IUM A;  1EWL A;  2BTW B;  4CZW A;  3I3T A;  5JA7 A;  4YV8 A;  8PCH A;  1S4V A;  2FYE A;  4OEL A;  1QDQ A;  2F1G A;  4PAD A;  6PAD A;  1PXV A;  7PCK A;  4OVZ A;  4R3D A;  4D8I A;  4N4Z A;  2E03 A;  1GCB A;  2XU5 A;  3F75 A;  1AU3 A;  3E1Z B;  4HXD B;  4X6J A;  4RY2 A;  1EWO A;  1ZIV A;  4Q8H A;  3OQC A;  4OEM A;  2E02 A;  3DF0 A;  3BCN A;  3PNR A;  2YJC A;  3AI8 A;  4RF1 A;  5EZS A;  2GHU A;  4G54 A;  2G8E A;  3QT4 A;  1YVB A;  4YYR A;  4CDD B;  4W5C A;  2DJF B;  1Y08 A;  4QRV A;  4BOZ A;  1PIP A;  2FO5 A;  1AU0 A;  1SNK A;  3P5U A;  1STF E;  2WBF X;  3C0R A;  3OVX A;  4OVZ B;  3LFY A;  2B1N A;  3OF9 A;  4DMY A;  2R6N A;  3QSD A;  4BQV A;  2G6D A;  3RVV A;  4ZTB A;  1CV8 A;  1IWD A;  3IEJ A;  4I04 A;  1F29 A;  5CVN B;  2FRA A;  2AU1 A;  5JH3 A;  5PAD A;  4BPV A;  1AYU A;  2DC8 A;  2XU4 A;  3MTV A;  1AYW A;  3BOW A;  1NL6 A;  2JQG R;  2Z84 A;  4CDE B;  1F2A A;  2ARY A;  3KW9 A;  2AIM A;  2AS8 A;  3IMA A;  2FRQ A;  3ZUA A;  1PBH A;  2Y5B A;  4YYQ A;  2OUL A;  3N4C A;  2JRI A;  1PPO A;  2VHF A;  4DMX A;  1MDW A;  4M0W A;  1CQD A;  1MEM A;  2JTC A;  2HHN A;  4MI7 A;  3KFQ A;  3MOR A;  4XR7 A;  2J7Q A;  4BS5 A;  1QOL A;  2UZJ A;  1VJV A;  4YYU A;  3WXE A;  4P6E A;  4CDC B;  1Y4H A;  2IPP B;  2E00 A;  1ME3 A;  1NB3 A;  1BP4 A;  2E01 A;  4FIP A;  1AEC A;  3GCB A;  3PBH A;  2CB5 A;  2R9F A;  3O1G A;  2G7Y A;  1ITO A;  1SP4 B;  3H89 A;  1MHW A;  3E9S A;  1CVZ A;  2FTD A;  1GEC E;  3P5W A;  2IBI A;  1FH0 A;  2P0R A;  1KFU L;  1F2C A;  3B79 A;  3C9E A;  3BC3 A;  1EF7 A;  4PP1 A;  2DZZ A;  4QRG A;  3CBK A;  3N3K A;  2AYN A;  3PSE A;  3WXF A;  4FJC A;  3D6S A;  3S3Q A;  5CHV A;  1PE6 A;  4REZ A;  1U9W A;  1BQI A;  3MTN A;  3KX1 A;  1A6R A;  1K3B B;  4YVA A;  2AUX A;  3KWZ A;  4CDF B;  3CH2 X;  4YYW A;  2AUZ A;  2YJ9 A;  2BDL A;  3S3R A;  2XU3 A;  2PAD A;  3B21 A;  3OF8 A;  3BPF A;  3K8U A;  5EF4 A;  4I05 A;  2FT2 A;  3P5X A;  3MP2 A;  1PAD A;  2NQA A;  4OW0 A;  5KO3 A;  3F5V A;  4YYS A;  1KHQ A;  5EGW A;  3O65 A;  1U5I A;  4KLB A;  1BGO A;  3N3G A;  1TLO A;  4BOU A;  4MM3 B;  1AYV A;  4BOS A;  3OVZ A;  4MSX A;  1THE A;  3PT2 A;  3I06 A;  4BOQ A;  2DC7 A;  1CB5 A;  4AXL A;  2HH5 A;  4Q8G A;  4PP2 E;  3MHH A;  1X9Y A;  2HD5 A;  1TL9 A;  2H7J A;  5CVM A;  4RNA A;  1DEU A;  1JQP A;  1PPN A;  2DCB A;  1YZB A;  1QXP A;  3BBA A;  2DCC A;  1CS8 A;  3RVX A;  1KHP A;  4W4U A;  1XKG A;  1ATK A;  3ZNH A;  2XU1 A;  2B1M A;  4X6I A;  3O0U A;  1EWM A;  1U9V A;  5JZE A;  3PW3 A;  3H6S A;  1DF0 A;  4K7C A;  3HWN A;  3K24 A;  2R9N A;  2FUD A;  4MZO A;  1YT7 A;  3H7D A;  3NHE A;  2R9C A;  3KKU A;  3HHI A;  3TMP A; 
#chains in the Genus database with same CATH homology
 2OZ2 A;  1YAL A;  2NQD B;  1KXR A;  2DJG B;  2ACT A;  1ME4 A;  2C0Y A;  2AVW A;  1HUC B;  4X6H A;  1CTE A;  1NLJ A;  4W5B A;  5A24 A;  3CBJ A;  3KWB X;  4N8W A;  2FQ9 A;  4P6G A;  3IOQ A;  1Q6K A;  1U9Q X;  3OIS A;  2DC6 A;  3TNX A;  2YJB A;  1AU4 A;  5CHT A;  3ERV A;  1CPJ A;  1EWP A;  2DZY A;  1NPZ A;  1TU6 A;  2P7U A;  1KFX L;  4AXM A;  2YJ2 A;  4QRX A;  3PDF A;  1NB5 A;  3LXS A;  9PAP A;  3RVW A;  1PPP A;  2CIO A;  4MZS A;  1AIM A;  5F02 A;  3M99 A;  3HHA A;  3USV A;  3D9W A;  2OP3 A;  3P5V A;  3BWK A;  1NQC A;  3K9M A;  3H8B A;  1YK7 A;  1VSN A;  4YYV A;  1ICF A;  3KSE A;  1QMY A;  3CH3 X;  3MHS A;  4NV8 A;  2R9O A;  1POP A;  2DC9 A;  1MEG A;  5FPW A;  3V6C A;  2NQG A;  1F2B A;  5J94 A;  4QBB A;  3HD3 A;  1MS6 A;  1GMY A;  1O0E A;  2GFO A;  4BS6 A;  2O6X A;  4WA6 A;  5CVO B;  2ATO A;  2BDZ A;  3V6E A;  2BSZ A;  1BY8 A;  1E2T A;  2DCA A;  1CJL A;  3WXG A;  3IHP A;  2NQI A;  4HWY A;  1GLO A;  4PI3 A;  1PCI A;  2HXZ A;  2G8J A;  2Y6E A;  2F7D A;  3BPM A;  3IUT A;  3H8C A;  2YJ8 A;  2PNS A;  4QH6 A;  1W4T A;  4BSQ A;  2DCD A;  3QJ3 A;  4N79 A;  1AU2 A;  4XUI A;  2PRE A;  2VHS A;  2PBH A;  4ZUX U;  1MIR A;  3U8E A;  2R9M A;  1PPD A;  1U9X A;  2JQF R;  1M6D A;  1YK8 A;  1ZCM A;  2P86 A;  4FK5 A;  1CSB B;  1W5R A;  4I07 A;  2AYO A;  5K16 A;  3IV2 A;  1EWL A;  4CZW A;  3I3T A;  5JA7 A;  4YV8 A;  8PCH A;  1S4V A;  2FYE A;  4OEL A;  1QDQ A;  2F1G A;  4PAD A;  6PAD A;  1PXV A;  7PCK A;  4N4Z A;  2E03 A;  1GCB A;  2XU5 A;  3F75 A;  1AU3 A;  3E1Z B;  4X6J A;  4RY2 A;  1EWO A;  1ZIV A;  4Q8H A;  4OEM A;  2E02 A;  3DF0 A;  3BCN A;  3PNR A;  2YJC A;  3AI8 A;  2GHU A;  4G54 A;  2G8E A;  3QT4 A;  1YVB A;  4YYR A;  4CDD B;  4W5C A;  2DJF B;  1Y08 A;  2VFB A;  4QRV A;  1PIP A;  2FO5 A;  1AU0 A;  1SNK A;  3P5U A;  1STF E;  2WBF X;  3OVX A;  3LFY A;  2B1N A;  3OF9 A;  4DMY A;  2R6N A;  3QSD A;  4BQV A;  2G6D A;  3RVV A;  1CV8 A;  1IWD A;  3IEJ A;  4I04 A;  1F29 A;  5CVN B;  2FRA A;  2AU1 A;  5JH3 A;  2VFC A;  5PAD A;  1AYU A;  2DC8 A;  2XU4 A;  4BPV A;  1AYW A;  3BOW A;  1NL6 A;  2JQG R;  4CDE B;  1F2A A;  2ARY A;  3KW9 A;  2AIM A;  2AS8 A;  3IMA A;  2FRQ A;  3ZUA A;  1PBH A;  2Y5B A;  4YYQ A;  2OUL A;  3N4C A;  1PPO A;  2VHF A;  4DMX A;  1MDW A;  1CQD A;  1MEM A;  2HHN A;  3KFQ A;  3MOR A;  4XR7 A;  4BS5 A;  1QOL A;  1VJV A;  4YYU A;  3WXE A;  4P6E A;  4CDC B;  1Y4H A;  2IPP B;  2E00 A;  1ME3 A;  1NB3 A;  1BP4 A;  2E01 A;  4FIP A;  4B55 A;  1AEC A;  3GCB A;  3PBH A;  2CB5 A;  3LTW A;  2R9F A;  3O1G A;  2G7Y A;  1ITO A;  1SP4 B;  3H89 A;  1MHW A;  1CVZ A;  2FTD A;  1GEC E;  3P5W A;  2IBI A;  1FH0 A;  2P0R A;  1KFU L;  1F2C A;  3B79 A;  3C9E A;  3BC3 A;  1EF7 A;  4PP1 A;  4GUZ A;  2DZZ A;  4QRG A;  3CBK A;  3N3K A;  2AYN A;  3WXF A;  4FJC A;  3D6S A;  3S3Q A;  5CHV A;  1PE6 A;  1U9W A;  1BQI A;  3MTN A;  3KX1 A;  1A6R A;  1K3B B;  4YVA A;  2AUX A;  3KWZ A;  4CDF B;  3CH2 X;  4YYW A;  2AUZ A;  2YJ9 A;  2BDL A;  3S3R A;  2XU3 A;  2PAD A;  3OF8 A;  3BPF A;  3K8U A;  5EF4 A;  4I05 A;  2FT2 A;  3P5X A;  1PAD A;  2NQA A;  3F5V A;  4YYS A;  1KHQ A;  4C5P A;  5EGW A;  1U5I A;  4KLB A;  1BGO A;  3N3G A;  1TLO A;  4NV7 A;  1AYV A;  3OVZ A;  4BGF A;  4MSX A;  1THE A;  3I06 A;  2DC7 A;  1CB5 A;  4AXL A;  2HH5 A;  4Q8G A;  4PP2 E;  3MHH A;  1GX3 A;  1X9Y A;  2HD5 A;  1TL9 A;  2H7J A;  5CVM A;  1DEU A;  1JQP A;  1PPN A;  2DCB A;  1QXP A;  2DCC A;  1CS8 A;  3RVX A;  1KHP A;  4W4U A;  1XKG A;  1ATK A;  2XU1 A;  2B1M A;  4X6I A;  3O0U A;  1EWM A;  1U9V A;  3PW3 A;  3H6S A;  1DF0 A;  4K7C A;  3HWN A;  3K24 A;  1W6F A;  2R9N A;  2FUD A;  4MZO A;  1YT7 A;  3H7D A;  3NHE A;  2R9C A;  3KKU A;  3HHI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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