2YJCA

Cathepsin l with a nitrile inhibitor
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
220
structure length
219
Chain Sequence
APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTSDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords CATHEPSIN L1
publication title Halogen Bonding at the Active Sites of Human Cathepsin L and Mek1 Kinase: Efficient Interactions in Different Environments.
pubmed doi rcsb
source organism Homo sapiens
total genus 74
structure length 219
sequence length 220
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2011-05-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2yjcA00
4CZWA 4QRXA 1NB3A 1F29A 2DC6A 3O0UA 1GCBA 1KHPA 1VJVA 2E01A 2DC7A 2BDLA 5K16A 4QBBA 2FRAA 2VHFA 2R9CA 4DMYA 1QMYA 3KWBX 3ZUAA 2FQ9A 3I06A 2JQFR 3IMAA 3S3RA 5JA7A 1ZIVA 3TNXA 1YT7A 3HD3A 1JQPA 3BC3A 1TL9A 1ITOA 1U5IA 2PNSA 1KFUL 4YYUA 4BPVA 5PADA 2R9FA 1VSNA 1ZCMA 3E1ZB 1CB5A 1DF0A 3K24A 3N3KA 2IPPB 1A6RA 2G8EA 5FPWA 1CTEA 2G6DA 7PCKA 2FRQA 4K7CA 4G54A 5EF4A 1YK7A 2P0RA 2E02A 2GHUA 4YYSA 1ME3A 1AU2A 2FT2A 4N8WA 3CBKA 4PI3A 4ZUXU 4DMXA 2ATOA 1PE6A 4XUIA 2Y5BA 2P86A 3BOWA 2WBFX 2R9OA 3OF8A 1F2AA 4YV8A 2P7UA 3PW3A 3B79A 5CVOB 1YVBA 1AYVA 3PBHA 3V6CA 4KLBA 4N79A 1BQIA 2DC8A 5CHVA 1X9YA 4I05A 2H7JA 4OEMA 1NQCA 4P6GA 2HD5A 3OVZA 1QXPA 1Q6KA 3KFQA 3WXFA 2AVWA 1EWOA 1YALA 1K3BB 1IWDA 1M6DA 4CDFB 3USVA 3DF0A 1TU6A 2PREA 3D6SA 3M99A 2FYEA 3QT4A 3BWKA 1EWPA 2F1GA 4Q8GA 2Y6EA 3KW9A 1PPPA 8PCHA 1MS6A 4PADA 3F75A 1PBHA 1CS8A 1AECA 1U9QX 3OF9A 1BGOA 3O1GA 2AUZA 1AYUA 3MORA 1PPDA 2BDZA 2NQAA 4AXLA 4W5BA 4I04A 2FTDA 1POPA 5F02A 4N4ZA 4CDCB 3BCNA 3OVXA 4FIPA 3I3TA 1CJLA 3AI8A 1CQDA 1MEGA 2AYNA 4BSQA 1ME4A 3HWNA 2G8JA 1AU3A 4QRGA 3C9EA 3IUTA 2R9MA 4I07A 3H8BA 1NLJA 2VHSA 4YYQA 2YJ8A 5JH3A 3IHPA 1NL6A 2O6XA 3N3GA 4AXMA 1BY8A 2NQIA 1AU0A 2HH5A 2DJFB 2IBIA 1BP4A 3KX1A 3MHSA 3RVVA 1U9XA 3N4CA 5A24A 4OELA 2HHNA 2NQDB 3H8CA 1GECE 1CVZA 1CSBB 2YJ2A 2DZYA 2XU3A 2XU4A 1SP4B 2OULA 3CH3X 1THEA 2OP3A 6PADA 3H7DA 3IEJA 3K9MA 4WA6A 1KHQA 4YYRA 1PXVA 5EGWA 4PP1A 1S4VA 4CDEB 1F2CA 4HWYA 1MIRA 4QRVA 1Y4HA 2JQGR 4RY2A 1EWLA 1AU4A 2FUDA 3GCBA 3H6SA 1KFXL 1XKGA 4Q8HA 4XR7A 3CH2X 3P5VA 3IOQA 1GLOA 3MHHA 4X6JA 1DEUA 2R9NA 1AYWA 1MEMA 1PADA 3P5XA 1NB5A 2NQGA 2B1MA 4CDDB 2HXZA 4MSXA 3F5VA 1ICFA 2AU1A 1SNKA 1KXRA 1U9WA 1PPNA 1GMYA 2DCDA 2YJ9A 2DCAA 1EWMA 2AYOA 4YVAA 3BPMA 1FH0A 1STFE 3MTNA 4X6HA 3RVWA 2C0YA 2FO5A 4FJCA 1CPJA 2B1NA 2XU1A 4X6IA 3QJ3A 2G7YA 1QDQA 3OISA 4P6EA 3RVXA 1Y08A 3NHEA 3KSEA 3LFYA 3HHAA 1U9VA 1O0EA 2PADA 2CB5A 2YJBA 3PDFA 1MHWA 3KKUA 4FK5A 1PPOA 1YK8A 1EF7A 5J94A 4BQVA 3KWZA 5CVNB 2AS8A 2YJCA 1ATKA 3LXSA 3ERVA 2E03A 3HHIA 3P5WA 3H89A 2ARYA 4QH6A 3CBJA 4BS5A 1TLOA 3P5UA 2DCBA 3U8EA 1HUCB 1QOLA 2OZ2A 2AIMA 1MDWA 2GFOA 4MZSA 4MZOA 1PIPA 2CIOA 1PCIA 4YYVA 9PAPA 3IV2A 2AUXA 4BS6A 4W4UA 4YYWA 5CHTA 2XU5A 2ACTA 2R6NA 3WXEA 1CV8A 2E00A 3WXGA 4W5CA 3BPFA 2DZZA 3K8UA 2PBHA 1F2BA 1AIMA 2DCCA 2DC9A 4PP2E 3PNRA 3QSDA 1NPZA 3S3QA 3V6EA 2DJGB 2F7DA 5CVMA
chains in the Genus database with same CATH superfamily
4CZWA 4QRXA 1NB3A 4RNAA 4RKXA 1F29A 2DC6A 3O0UA 1GCBA 1KHPA 4IP3A 1VJVA 2E01A 2DC7A 2BDLA 5K16A 4QBBA 2FRAA 2VHFA 2BU3A 2R9CA 4DMYA 1QMYA 3KWBX 5EZSA 3ZUAA 2FQ9A 3I06A 2JQFR 3IMAA 4ZTBA 3S3RA 5JA7A 4HXDB 1ZIVA 3TNXA 1YT7A 4IUMA 3HD3A 1JQPA 3BC3A 1TL9A 1ITOA 1U5IA 2PNSA 1KFUL 4YYUA 4BPVA 5PADA 2DOSA 2R9FA 1VSNA 1ZCMA 3E1ZB 1UKFA 1CB5A 1DF0A 4BOQA 3K24A 4RF0A 3N3KA 2IPPB 1A6RA 2G8EA 4XZXA 5FPWA 2JRIA 1CTEA 2G6DA 7PCKA 2FRQA 4K7CA 4G54A 5EF4A 1YK7A 2P0RA 2E02A 2GHUA 4YYSA 1ME3A 1AU2A 2FT2A 4N8WA 3CBKA 4PI3A 4ZUXU 4DMXA 2ATOA 1PE6A 4XUIA 3PRMA 3W31A 2Y5BA 2P86A 3BOWA 2WBFX 2R9OA 3OF8A 4D8BA 1F2AA 4YV8A 2P7UA 3PW3A 3B79A 5JZEA 5CVOB 5EZQA 1YVBA 1AYVA 4R3DA 3PBHA 3V6CA 4P16A 3O65A 4KLBA 4N79A 2JTCA 1BQIA 2DC8A 5CHVA 1X9YA 4I05A 2H7JA 4OEMA 4BOZA 1NQCA 4P6GA 2HD5A 3PHWA 3BB7A 3OVZA 1QXPA 4PT5A 1Q6KA 3KFQA 3WXFA 2AVWA 4WURA 1EWOA 1YALA 1K3BB 1IWDA 1M6DA 1PVJA 4CDFB 3USVA 3MTVA 4OVZA 3ZNHA 3DF0A 5E6JA 1TU6A 2PREA 3D6SA 4A5UA 3M99A 2FYEA 3PRPA 2FE8A 3QT4A 3BWKA 1EWPA 2F1GA 4Q8GA 3MP2A 2Y6EA 2UZJA 4BOSA 3KW9A 1PPPA 8PCHA 1MS6A 4PADA 2Z84A 3TMPA 3F75A 3OQCA 1PBHA 1CS8A 1AECA 4REZA 4GUAA 1U9QX 3OF9A 1BGOA 3O1GA 2AUZA 1AYUA 3MORA 1PPDA 3IFUA 2BDZA 2NQAA 2J7QC 4AXLA 4W5BA 4I04A 2FTDA 4OW0A 1POPA 5F02A 4N4ZA 4CDCB 3BCNA 3OVXA 4FIPA 3I3TA 3W30A 1CJLA 3AI8A 1CQDA 1MEGA 2AYNA 4BSQA 1ME4A 3HWNA 2G8JA 1AU3A 4QRGA 2AGAA 3C9EA 3IUTA 2R9MA 1NLJA 3H8BA 4I07A 2VHSA 4YYQA 2YJ8A 5JH3A 4D8IA 3IHPA 1NL6A 2O6XA 3N3GA 4AXMA 1BY8A 2NQIA 1AU0A 2BTWA 2HH5A 3PT2A 2DJFB 2IBIA 1BP4A 3KX1A 3MHSA 3PHXA 3RVVA 1U9XA 3N4CA 5A24A 4OELA 1DKIA 2HHNA 2NQDB 3H8CA 1GECE 1CVZA 3MJ5A 1CSBB 2YJ2A 2DZYA 2XU3A 2XU4A 1SP4B 2OULA 3CH3X 1THEA 2OP3A 6PADA 3H7DA 3IEJA 3K9MA 4WA6A 1KHQA 4YYRA 1PXVA 3B21A 5EGWA 4PP1A 3TRKA 1S4VA 4CDEB 1F2CA 4HWYA 1MIRA 4QRVA 2J7QA 1Y4HA 2JQGR 4MI7A 4RY2A 3RNVA 1EWLA 4RF1A 1AU4A 2FUDA 3BY4A 3GCBA 3H6SA 1KFXL 1XKGA 4Q8HA 4XR7A 3CH2X 3P5VA 3IOQA 1GLOA 3MHHA 4X6JA 1DEUA 2R9NA 4OVZB 1AYWA 1MEMA 1PADA 3P5XA 1NB5A 2NQGA 2B1MA 4CDDB 2HXZA 4MSXA 3F5VA 1ICFA 2AU1A 1SNKA 4MM3B 1KXRA 1U9WA 1PPNA 1GMYA 2DCDA 2YJ9A 2DCAA 1EWMA 2AYOA 4YVAA 5KO3A 3BPMA 1FH0A 1STFE 3MTNA 4X6HA 3RVWA 2C0YA 2FO5A 4FJCA 1YZBA 1CPJA 2B1NA 2XU1A 4X6IA 3QJ3A 2G7YA 1QDQA 3OISA 4P6EA 3RVXA 1Y08A 3NHEA 4BOPA 3KSEA 3LFYA 3HHAA 1U9VA 1O0EA 2PADA 2CB5A 3PDFA 2HWKA 2YJBA 1MHWA 3KKUA 4FK5A 1PPOA 1YK8A 1EF7A 5J94A 4BQVA 3KWZA 5CVNB 2AS8A 2YJCA 1ATKA 3LXSA 3E9SA 3ERVA 2E03A 3HHIA 3P5WA 3H89A 2ARYA 4QH6A 3CBJA 3C0RA 4BS5A 4BOUA 1TLOA 3P5UA 2DCBA 3U8EA 1HUCB 1QOLA 2OZ2A 2AIMA 4M0WA 1MDWA 2GFOA 4MZSA 4MZOA 1PIPA 2CIOA 3BBAA 1PCIA 2BTWB 4YYVA 9PAPA 3PHUA 3IV2A 2AUXA 4BS6A 4W4UA 4YYWA 5CHTA 2XU5A 2ACTA 2R6NA 3WXEA 1CV8A 2E00A 3WXGA 4W5CA 3BPFA 2DZZA 3K8UA 2PBHA 1F2BA 1AIMA 2DCCA 2DC9A 3QSDA 3PNRA 4PP2E 1NPZA 4D8EA 3PSEA 3S3QA 3V6EA 2DJGB 2F7DA 5CVMA
chains in the Genus database with same CATH topology
4CZWA 4QRXA 1NB3A 1F29A 2DC6A 3O0UA 1GCBA 1KHPA 1VJVA 2E01A 2DC7A 2BDLA 5K16A 4QBBA 2FRAA 2BSZA 2VHFA 2R9CA 4DMYA 1QMYA 3KWBX 3ZUAA 2FQ9A 3I06A 2JQFR 3IMAA 3S3RA 5JA7A 1ZIVA 3TNXA 1GX3A 1YT7A 3HD3A 1JQPA 3BC3A 1TL9A 1ITOA 1U5IA 2PNSA 1KFUL 4YYUA 4BPVA 5PADA 2R9FA 1VSNA 1ZCMA 3E1ZB 1CB5A 1DF0A 3K24A 3N3KA 2IPPB 1A6RA 2G8EA 4BGFA 5FPWA 1CTEA 2G6DA 7PCKA 2FRQA 4K7CA 4G54A 5EF4A 1YK7A 2P0RA 2E02A 2GHUA 4YYSA 1ME3A 1AU2A 2FT2A 4N8WA 3CBKA 4PI3A 4ZUXU 4DMXA 2ATOA 1PE6A 4XUIA 2Y5BA 2P86A 3BOWA 2WBFX 2R9OA 3OF8A 1F2AA 4YV8A 2P7UA 3PW3A 3B79A 5CVOB 1YVBA 1AYVA 3PBHA 3V6CA 4KLBA 4N79A 1BQIA 2DC8A 5CHVA 1X9YA 4I05A 2H7JA 4OEMA 1NQCA 4P6GA 2HD5A 3OVZA 1QXPA 1Q6KA 3KFQA 3WXFA 2AVWA 1EWOA 1YALA 1K3BB 1IWDA 1M6DA 4CDFB 3USVA 3DF0A 1TU6A 2PREA 3D6SA 3M99A 2FYEA 3QT4A 3BWKA 1EWPA 2F1GA 4Q8GA 2Y6EA 3KW9A 1PPPA 8PCHA 1MS6A 4PADA 3F75A 1PBHA 1CS8A 1AECA 1U9QX 3OF9A 1BGOA 3O1GA 2AUZA 1AYUA 3MORA 1PPDA 2BDZA 2NQAA 4AXLA 4W5BA 4I04A 2FTDA 1POPA 5F02A 4N4ZA 4CDCB 4FIPA 3BCNA 3OVXA 3I3TA 1CJLA 3AI8A 1CQDA 1MEGA 2AYNA 4BSQA 1ME4A 3HWNA 2G8JA 2VFBA 1AU3A 4QRGA 3C9EA 3IUTA 2R9MA 4I07A 3H8BA 1NLJA 2VHSA 4YYQA 2YJ8A 5JH3A 3IHPA 1W5RA 4B55A 1NL6A 2O6XA 3N3GA 4AXMA 1BY8A 2NQIA 1AU0A 2HH5A 2DJFB 2IBIA 1BP4A 3KX1A 3MHSA 3RVVA 1U9XA 3N4CA 5A24A 4OELA 2HHNA 2NQDB 3H8CA 1GECE 1CVZA 1CSBB 2YJ2A 2VFCA 2DZYA 2XU3A 2XU4A 1SP4B 2OULA 3CH3X 1THEA 2OP3A 6PADA 3H7DA 3IEJA 3K9MA 4WA6A 1KHQA 4YYRA 1PXVA 5EGWA 4PP1A 1W4TA 3D9WA 1S4VA 4CDEB 1F2CA 4HWYA 1MIRA 4QRVA 1E2TA 1Y4HA 2JQGR 4RY2A 1EWLA 1AU4A 2FUDA 3GCBA 3H6SA 1KFXL 1XKGA 4Q8HA 4XR7A 3CH2X 3P5VA 3IOQA 1GLOA 3MHHA 4X6JA 1DEUA 2R9NA 1AYWA 1MEMA 1PADA 3P5XA 1NB5A 2NQGA 2B1MA 3LTWA 4CDDB 2HXZA 4MSXA 3F5VA 1ICFA 2AU1A 1SNKA 1KXRA 1U9WA 1PPNA 1GMYA 2DCDA 2YJ9A 2DCAA 1EWMA 2AYOA 4YVAA 3BPMA 1FH0A 1STFE 3MTNA 4X6HA 3RVWA 2C0YA 2FO5A 4FJCA 1CPJA 2B1NA 2XU1A 4X6IA 3QJ3A 2G7YA 1QDQA 3OISA 4P6EA 3RVXA 1Y08A 3NHEA 3KSEA 3LFYA 3HHAA 1U9VA 1O0EA 2PADA 2CB5A 2YJBA 3PDFA 1MHWA 3KKUA 4FK5A 1PPOA 1YK8A 1EF7A 4C5PA 5J94A 4BQVA 3KWZA 5CVNB 2AS8A 2YJCA 1ATKA 3LXSA 3ERVA 2E03A 1W6FA 3HHIA 3P5WA 3H89A 2ARYA 4QH6A 3CBJA 4BS5A 1TLOA 3P5UA 2DCBA 3U8EA 1HUCB 1QOLA 2OZ2A 2AIMA 1MDWA 2GFOA 4MZSA 4MZOA 1PIPA 2CIOA 1PCIA 4YYVA 9PAPA 3IV2A 2AUXA 4BS6A 4NV7A 4W4UA 4YYWA 5CHTA 2XU5A 2ACTA 2R6NA 3WXEA 1CV8A 2E00A 3WXGA 4W5CA 3BPFA 2DZZA 3K8UA 2PBHA 1F2BA 1AIMA 4GUZA 2DCCA 2DC9A 3QSDA 3PNRA 4NV8A 4PP2E 1NPZA 3S3QA 3V6EA 2DJGB 2F7DA 5CVMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4CZW A;  4QRX A;  1NB3 A;  1F29 A;  2DC6 A;  3O0U A;  1GCB A;  1KHP A;  1VJV A;  2E01 A;  2DC7 A;  2BDL A;  5K16 A;  4QBB A;  2FRA A;  2VHF A;  2R9C A;  4DMY A;  1QMY A;  3KWB X;  3ZUA A;  2FQ9 A;  3I06 A;  2JQF R;  3IMA A;  3S3R A;  5JA7 A;  1ZIV A;  3TNX A;  1YT7 A;  3HD3 A;  1JQP A;  3BC3 A;  1TL9 A;  1ITO A;  1U5I A;  2PNS A;  1KFU L;  4YYU A;  4BPV A;  5PAD A;  2R9F A;  1VSN A;  1ZCM A;  3E1Z B;  1CB5 A;  1DF0 A;  3K24 A;  3N3K A;  2IPP B;  1A6R A;  2G8E A;  5FPW A;  1CTE A;  2G6D A;  7PCK A;  2FRQ A;  4K7C A;  4G54 A;  5EF4 A;  1YK7 A;  2P0R A;  2E02 A;  2GHU A;  4YYS A;  1ME3 A;  1AU2 A;  2FT2 A;  4N8W A;  3CBK A;  4PI3 A;  4ZUX U;  4DMX A;  2ATO A;  1PE6 A;  4XUI A;  2Y5B A;  2P86 A;  3BOW A;  2WBF X;  2R9O A;  3OF8 A;  1F2A A;  4YV8 A;  2P7U A;  3PW3 A;  3B79 A;  5CVO B;  1YVB A;  1AYV A;  3PBH A;  3V6C A;  4KLB A;  4N79 A;  1BQI A;  2DC8 A;  5CHV A;  1X9Y A;  4I05 A;  2H7J A;  4OEM A;  1NQC A;  4P6G A;  2HD5 A;  3OVZ A;  1QXP A;  1Q6K A;  3KFQ A;  3WXF A;  2AVW A;  1EWO A;  1YAL A;  1K3B B;  1IWD A;  1M6D A;  4CDF B;  3USV A;  3DF0 A;  1TU6 A;  2PRE A;  3D6S A;  3M99 A;  2FYE A;  3QT4 A;  3BWK A;  1EWP A;  2F1G A;  4Q8G A;  2Y6E A;  3KW9 A;  1PPP A;  8PCH A;  1MS6 A;  4PAD A;  3F75 A;  1PBH A;  1CS8 A;  1AEC A;  1U9Q X;  3OF9 A;  1BGO A;  3O1G A;  2AUZ A;  1AYU A;  3MOR A;  1PPD A;  2BDZ A;  2NQA A;  4AXL A;  4W5B A;  4I04 A;  2FTD A;  1POP A;  5F02 A;  4N4Z A;  4CDC B;  3BCN A;  3OVX A;  4FIP A;  3I3T A;  1CJL A;  3AI8 A;  1CQD A;  1MEG A;  2AYN A;  4BSQ A;  1ME4 A;  3HWN A;  2G8J A;  1AU3 A;  4QRG A;  3C9E A;  3IUT A;  2R9M A;  4I07 A;  3H8B A;  1NLJ A;  2VHS A;  4YYQ A;  2YJ8 A;  5JH3 A;  3IHP A;  1NL6 A;  2O6X A;  3N3G A;  4AXM A;  1BY8 A;  2NQI A;  1AU0 A;  2HH5 A;  2DJF B;  2IBI A;  1BP4 A;  3KX1 A;  3MHS A;  3RVV A;  1U9X A;  3N4C A;  5A24 A;  4OEL A;  2HHN A;  2NQD B;  3H8C A;  1GEC E;  1CVZ A;  1CSB B;  2YJ2 A;  2DZY A;  2XU3 A;  2XU4 A;  1SP4 B;  2OUL A;  3CH3 X;  1THE A;  2OP3 A;  6PAD A;  3H7D A;  3IEJ A;  3K9M A;  4WA6 A;  1KHQ A;  4YYR A;  1PXV A;  5EGW A;  4PP1 A;  1S4V A;  4CDE B;  1F2C A;  4HWY A;  1MIR A;  4QRV A;  1Y4H A;  2JQG R;  4RY2 A;  1EWL A;  1AU4 A;  2FUD A;  3GCB A;  3H6S A;  1KFX L;  1XKG A;  4Q8H A;  4XR7 A;  3CH2 X;  3P5V A;  3IOQ A;  1GLO A;  3MHH A;  4X6J A;  1DEU A;  2R9N A;  1AYW A;  1MEM A;  1PAD A;  3P5X A;  1NB5 A;  2NQG A;  2B1M A;  4CDD B;  2HXZ A;  4MSX A;  3F5V A;  1ICF A;  2AU1 A;  1SNK A;  1KXR A;  1U9W A;  1PPN A;  1GMY A;  2DCD A;  2YJ9 A;  2DCA A;  1EWM A;  2AYO A;  4YVA A;  3BPM A;  1FH0 A;  1STF E;  3MTN A;  4X6H A;  3RVW A;  2C0Y A;  2FO5 A;  4FJC A;  1CPJ A;  2B1N A;  2XU1 A;  4X6I A;  3QJ3 A;  2G7Y A;  1QDQ A;  3OIS A;  4P6E A;  3RVX A;  1Y08 A;  3NHE A;  3KSE A;  3LFY A;  3HHA A;  1U9V A;  1O0E A;  2PAD A;  2CB5 A;  2YJB A;  3PDF A;  1MHW A;  3KKU A;  4FK5 A;  1PPO A;  1YK8 A;  1EF7 A;  5J94 A;  4BQV A;  3KWZ A;  5CVN B;  2AS8 A;  2YJC A;  1ATK A;  3LXS A;  3ERV A;  2E03 A;  3HHI A;  3P5W A;  3H89 A;  2ARY A;  4QH6 A;  3CBJ A;  4BS5 A;  1TLO A;  3P5U A;  2DCB A;  3U8E A;  1HUC B;  1QOL A;  2OZ2 A;  2AIM A;  1MDW A;  2GFO A;  4MZS A;  4MZO A;  1PIP A;  2CIO A;  1PCI A;  4YYV A;  9PAP A;  3IV2 A;  2AUX A;  4BS6 A;  4W4U A;  4YYW A;  5CHT A;  2XU5 A;  2ACT A;  2R6N A;  3WXE A;  1CV8 A;  2E00 A;  3WXG A;  4W5C A;  3BPF A;  2DZZ A;  3K8U A;  2PBH A;  1F2B A;  1AIM A;  2DCC A;  2DC9 A;  4PP2 E;  3PNR A;  3QSD A;  1NPZ A;  3S3Q A;  3V6E A;  2DJG B;  2F7D A;  5CVM A; 
#chains in the Genus database with same CATH topology
 4CZW A;  4QRX A;  1NB3 A;  4RNA A;  4RKX A;  1F29 A;  2DC6 A;  3O0U A;  1GCB A;  1KHP A;  4IP3 A;  1VJV A;  2E01 A;  2DC7 A;  2BDL A;  5K16 A;  4QBB A;  2FRA A;  2VHF A;  2BU3 A;  2R9C A;  4DMY A;  1QMY A;  3KWB X;  5EZS A;  3ZUA A;  2FQ9 A;  3I06 A;  2JQF R;  3IMA A;  4ZTB A;  3S3R A;  5JA7 A;  4HXD B;  1ZIV A;  3TNX A;  1YT7 A;  4IUM A;  3HD3 A;  1JQP A;  3BC3 A;  1TL9 A;  1ITO A;  1U5I A;  2PNS A;  1KFU L;  4YYU A;  4BPV A;  5PAD A;  2DOS A;  2R9F A;  1VSN A;  1ZCM A;  3E1Z B;  1UKF A;  1CB5 A;  1DF0 A;  4BOQ A;  3K24 A;  4RF0 A;  3N3K A;  2IPP B;  1A6R A;  2G8E A;  4XZX A;  5FPW A;  2JRI A;  1CTE A;  2G6D A;  7PCK A;  2FRQ A;  4K7C A;  4G54 A;  5EF4 A;  1YK7 A;  2P0R A;  2E02 A;  2GHU A;  4YYS A;  1ME3 A;  1AU2 A;  2FT2 A;  4N8W A;  3CBK A;  4PI3 A;  4ZUX U;  4DMX A;  2ATO A;  1PE6 A;  4XUI A;  3PRM A;  3W31 A;  2Y5B A;  2P86 A;  3BOW A;  2WBF X;  2R9O A;  3OF8 A;  4D8B A;  1F2A A;  4YV8 A;  2P7U A;  3PW3 A;  3B79 A;  5JZE A;  5CVO B;  5EZQ A;  1YVB A;  1AYV A;  4R3D A;  3PBH A;  3V6C A;  4P16 A;  3O65 A;  4KLB A;  4N79 A;  2JTC A;  1BQI A;  2DC8 A;  5CHV A;  1X9Y A;  4I05 A;  2H7J A;  4OEM A;  4BOZ A;  1NQC A;  4P6G A;  2HD5 A;  3PHW A;  3BB7 A;  3OVZ A;  1QXP A;  4PT5 A;  1Q6K A;  3KFQ A;  3WXF A;  2AVW A;  4WUR A;  1EWO A;  1YAL A;  1K3B B;  1IWD A;  1M6D A;  1PVJ A;  4CDF B;  3USV A;  3MTV A;  4OVZ A;  3ZNH A;  3DF0 A;  5E6J A;  1TU6 A;  2PRE A;  3D6S A;  4A5U A;  3M99 A;  2FYE A;  3PRP A;  2FE8 A;  3QT4 A;  3BWK A;  1EWP A;  2F1G A;  4Q8G A;  3MP2 A;  2Y6E A;  2UZJ A;  4BOS A;  3KW9 A;  1PPP A;  8PCH A;  1MS6 A;  4PAD A;  2Z84 A;  3TMP A;  3F75 A;  3OQC A;  1PBH A;  1CS8 A;  1AEC A;  4REZ A;  4GUA A;  1U9Q X;  3OF9 A;  1BGO A;  3O1G A;  2AUZ A;  1AYU A;  3MOR A;  1PPD A;  3IFU A;  2BDZ A;  2NQA A;  2J7Q C;  4AXL A;  4W5B A;  4I04 A;  2FTD A;  4OW0 A;  1POP A;  5F02 A;  4N4Z A;  4CDC B;  3BCN A;  3OVX A;  4FIP A;  3I3T A;  3W30 A;  1CJL A;  3AI8 A;  1CQD A;  1MEG A;  2AYN A;  4BSQ A;  1ME4 A;  3HWN A;  2G8J A;  1AU3 A;  4QRG A;  2AGA A;  3C9E A;  3IUT A;  2R9M A;  1NLJ A;  3H8B A;  4I07 A;  2VHS A;  4YYQ A;  2YJ8 A;  5JH3 A;  4D8I A;  3IHP A;  1NL6 A;  2O6X A;  3N3G A;  4AXM A;  1BY8 A;  2NQI A;  1AU0 A;  2BTW A;  2HH5 A;  3PT2 A;  2DJF B;  2IBI A;  1BP4 A;  3KX1 A;  3MHS A;  3PHX A;  3RVV A;  1U9X A;  3N4C A;  5A24 A;  4OEL A;  1DKI A;  2HHN A;  2NQD B;  3H8C A;  1GEC E;  1CVZ A;  3MJ5 A;  1CSB B;  2YJ2 A;  2DZY A;  2XU3 A;  2XU4 A;  1SP4 B;  2OUL A;  3CH3 X;  1THE A;  2OP3 A;  6PAD A;  3H7D A;  3IEJ A;  3K9M A;  4WA6 A;  1KHQ A;  4YYR A;  1PXV A;  3B21 A;  5EGW A;  4PP1 A;  3TRK A;  1S4V A;  4CDE B;  1F2C A;  4HWY A;  1MIR A;  4QRV A;  2J7Q A;  1Y4H A;  2JQG R;  4MI7 A;  4RY2 A;  3RNV A;  1EWL A;  4RF1 A;  1AU4 A;  2FUD A;  3BY4 A;  3GCB A;  3H6S A;  1KFX L;  1XKG A;  4Q8H A;  4XR7 A;  3CH2 X;  3P5V A;  3IOQ A;  1GLO A;  3MHH A;  4X6J A;  1DEU A;  2R9N A;  4OVZ B;  1AYW A;  1MEM A;  1PAD A;  3P5X A;  1NB5 A;  2NQG A;  2B1M A;  4CDD B;  2HXZ A;  4MSX A;  3F5V A;  1ICF A;  2AU1 A;  1SNK A;  4MM3 B;  1KXR A;  1U9W A;  1PPN A;  1GMY A;  2DCD A;  2YJ9 A;  2DCA A;  1EWM A;  2AYO A;  4YVA A;  5KO3 A;  3BPM A;  1FH0 A;  1STF E;  3MTN A;  4X6H A;  3RVW A;  2C0Y A;  2FO5 A;  4FJC A;  1YZB A;  1CPJ A;  2B1N A;  2XU1 A;  4X6I A;  3QJ3 A;  2G7Y A;  1QDQ A;  3OIS A;  4P6E A;  3RVX A;  1Y08 A;  3NHE A;  4BOP A;  3KSE A;  3LFY A;  3HHA A;  1U9V A;  1O0E A;  2PAD A;  2CB5 A;  3PDF A;  2HWK A;  2YJB A;  1MHW A;  3KKU A;  4FK5 A;  1PPO A;  1YK8 A;  1EF7 A;  5J94 A;  4BQV A;  3KWZ A;  5CVN B;  2AS8 A;  2YJC A;  1ATK A;  3LXS A;  3E9S A;  3ERV A;  2E03 A;  3HHI A;  3P5W A;  3H89 A;  2ARY A;  4QH6 A;  3CBJ A;  3C0R A;  4BS5 A;  4BOU A;  1TLO A;  3P5U A;  2DCB A;  3U8E A;  1HUC B;  1QOL A;  2OZ2 A;  2AIM A;  4M0W A;  1MDW A;  2GFO A;  4MZS A;  4MZO A;  1PIP A;  2CIO A;  3BBA A;  1PCI A;  2BTW B;  4YYV A;  9PAP A;  3PHU A;  3IV2 A;  2AUX A;  4BS6 A;  4W4U A;  4YYW A;  5CHT A;  2XU5 A;  2ACT A;  2R6N A;  3WXE A;  1CV8 A;  2E00 A;  3WXG A;  4W5C A;  3BPF A;  2DZZ A;  3K8U A;  2PBH A;  1F2B A;  1AIM A;  2DCC A;  2DC9 A;  3QSD A;  3PNR A;  4PP2 E;  1NPZ A;  4D8E A;  3PSE A;  3S3Q A;  3V6E A;  2DJG B;  2F7D A;  5CVM A; 
#chains in the Genus database with same CATH homology
 4CZW A;  4QRX A;  1NB3 A;  1F29 A;  2DC6 A;  3O0U A;  1GCB A;  1KHP A;  1VJV A;  2E01 A;  2DC7 A;  2BDL A;  5K16 A;  4QBB A;  2FRA A;  2BSZ A;  2VHF A;  2R9C A;  4DMY A;  1QMY A;  3KWB X;  3ZUA A;  2FQ9 A;  3I06 A;  2JQF R;  3IMA A;  3S3R A;  5JA7 A;  1ZIV A;  3TNX A;  1GX3 A;  1YT7 A;  3HD3 A;  1JQP A;  3BC3 A;  1TL9 A;  1ITO A;  1U5I A;  2PNS A;  1KFU L;  4YYU A;  4BPV A;  5PAD A;  2R9F A;  1VSN A;  1ZCM A;  3E1Z B;  1CB5 A;  1DF0 A;  3K24 A;  3N3K A;  2IPP B;  1A6R A;  2G8E A;  4BGF A;  5FPW A;  1CTE A;  2G6D A;  7PCK A;  2FRQ A;  4K7C A;  4G54 A;  5EF4 A;  1YK7 A;  2P0R A;  2E02 A;  2GHU A;  4YYS A;  1ME3 A;  1AU2 A;  2FT2 A;  4N8W A;  3CBK A;  4PI3 A;  4ZUX U;  4DMX A;  2ATO A;  1PE6 A;  4XUI A;  2Y5B A;  2P86 A;  3BOW A;  2WBF X;  2R9O A;  3OF8 A;  1F2A A;  4YV8 A;  2P7U A;  3PW3 A;  3B79 A;  5CVO B;  1YVB A;  1AYV A;  3PBH A;  3V6C A;  4KLB A;  4N79 A;  1BQI A;  2DC8 A;  5CHV A;  1X9Y A;  4I05 A;  2H7J A;  4OEM A;  1NQC A;  4P6G A;  2HD5 A;  3OVZ A;  1QXP A;  1Q6K A;  3KFQ A;  3WXF A;  2AVW A;  1EWO A;  1YAL A;  1K3B B;  1IWD A;  1M6D A;  4CDF B;  3USV A;  3DF0 A;  1TU6 A;  2PRE A;  3D6S A;  3M99 A;  2FYE A;  3QT4 A;  3BWK A;  1EWP A;  2F1G A;  4Q8G A;  2Y6E A;  3KW9 A;  1PPP A;  8PCH A;  1MS6 A;  4PAD A;  3F75 A;  1PBH A;  1CS8 A;  1AEC A;  1U9Q X;  3OF9 A;  1BGO A;  3O1G A;  2AUZ A;  1AYU A;  3MOR A;  1PPD A;  2BDZ A;  2NQA A;  4AXL A;  4W5B A;  4I04 A;  2FTD A;  1POP A;  5F02 A;  4N4Z A;  4CDC B;  4FIP A;  3BCN A;  3OVX A;  3I3T A;  1CJL A;  3AI8 A;  1CQD A;  1MEG A;  2AYN A;  4BSQ A;  1ME4 A;  3HWN A;  2G8J A;  2VFB A;  1AU3 A;  4QRG A;  3C9E A;  3IUT A;  2R9M A;  4I07 A;  3H8B A;  1NLJ A;  2VHS A;  4YYQ A;  2YJ8 A;  5JH3 A;  3IHP A;  1W5R A;  4B55 A;  1NL6 A;  2O6X A;  3N3G A;  4AXM A;  1BY8 A;  2NQI A;  1AU0 A;  2HH5 A;  2DJF B;  2IBI A;  1BP4 A;  3KX1 A;  3MHS A;  3RVV A;  1U9X A;  3N4C A;  5A24 A;  4OEL A;  2HHN A;  2NQD B;  3H8C A;  1GEC E;  1CVZ A;  1CSB B;  2YJ2 A;  2VFC A;  2DZY A;  2XU3 A;  2XU4 A;  1SP4 B;  2OUL A;  3CH3 X;  1THE A;  2OP3 A;  6PAD A;  3H7D A;  3IEJ A;  3K9M A;  4WA6 A;  1KHQ A;  4YYR A;  1PXV A;  5EGW A;  4PP1 A;  1W4T A;  3D9W A;  1S4V A;  4CDE B;  1F2C A;  4HWY A;  1MIR A;  4QRV A;  1E2T A;  1Y4H A;  2JQG R;  4RY2 A;  1EWL A;  1AU4 A;  2FUD A;  3GCB A;  3H6S A;  1KFX L;  1XKG A;  4Q8H A;  4XR7 A;  3CH2 X;  3P5V A;  3IOQ A;  1GLO A;  3MHH A;  4X6J A;  1DEU A;  2R9N A;  1AYW A;  1MEM A;  1PAD A;  3P5X A;  1NB5 A;  2NQG A;  2B1M A;  3LTW A;  4CDD B;  2HXZ A;  4MSX A;  3F5V A;  1ICF A;  2AU1 A;  1SNK A;  1KXR A;  1U9W A;  1PPN A;  1GMY A;  2DCD A;  2YJ9 A;  2DCA A;  1EWM A;  2AYO A;  4YVA A;  3BPM A;  1FH0 A;  1STF E;  3MTN A;  4X6H A;  3RVW A;  2C0Y A;  2FO5 A;  4FJC A;  1CPJ A;  2B1N A;  2XU1 A;  4X6I A;  3QJ3 A;  2G7Y A;  1QDQ A;  3OIS A;  4P6E A;  3RVX A;  1Y08 A;  3NHE A;  3KSE A;  3LFY A;  3HHA A;  1U9V A;  1O0E A;  2PAD A;  2CB5 A;  2YJB A;  3PDF A;  1MHW A;  3KKU A;  4FK5 A;  1PPO A;  1YK8 A;  1EF7 A;  4C5P A;  5J94 A;  4BQV A;  3KWZ A;  5CVN B;  2AS8 A;  2YJC A;  1ATK A;  3LXS A;  3ERV A;  2E03 A;  1W6F A;  3HHI A;  3P5W A;  3H89 A;  2ARY A;  4QH6 A;  3CBJ A;  4BS5 A;  1TLO A;  3P5U A;  2DCB A;  3U8E A;  1HUC B;  1QOL A;  2OZ2 A;  2AIM A;  1MDW A;  2GFO A;  4MZS A;  4MZO A;  1PIP A;  2CIO A;  1PCI A;  4YYV A;  9PAP A;  3IV2 A;  2AUX A;  4BS6 A;  4NV7 A;  4W4U A;  4YYW A;  5CHT A;  2XU5 A;  2ACT A;  2R6N A;  3WXE A;  1CV8 A;  2E00 A;  3WXG A;  4W5C A;  3BPF A;  2DZZ A;  3K8U A;  2PBH A;  1F2B A;  1AIM A;  4GUZ A;  2DCC A;  2DC9 A;  3QSD A;  3PNR A;  4NV8 A;  4PP2 E;  1NPZ A;  3S3Q A;  3V6E A;  2DJG B;  2F7D A;  5CVM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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