2YJCA

Cathepsin l with a nitrile inhibitor
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
220
structure length
219
Chain Sequence
APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTSDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Halogen Bonding at the Active Sites of Human Cathepsin L and Mek1 Kinase: Efficient Interactions in Different Environments.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase
molecule keywords CATHEPSIN L1
total genus 74
structure length 219
sequence length 220
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2011-05-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2yjcA00
3LFYA 4N8WA 3N3GA 5A24A 2YJ2A 1YT7A 1MS6A 3P5WA 2DCAA 2G8JA 1IWDA 1HUCB 2BDLA 2HD5A 5CHTA 2VHFA 3OF9A 4BQVA 1EF7A 1KXRA 4P6EA 4YYVA 1Y4HA 5F02A 4YYUA 2HXZA 1NPZA 1O0EA 4CDCB 2ATOA 1PPPA 1KFXL 2FQ9A 2PNSA 1CB5A 3ERVA 1POPA 5J94A 3TNXA 4AXMA 1AIMA 3BPFA 4FJCA 3IMAA 4I05A 3D6SA 1U9XA 3F5VA 3CBKA 1ME4A 1PIPA 4AXLA 3N4CA 4G54A 2DZYA 1U9WA 3GCBA 1STFE 2H7JA 1NB3A 1M6DA 1THEA 1SP4B 1TU6A 1CV8A 1AU3A 2O6XA 2OULA 1GCBA 1PPOA 1AU0A 4CDEB 3KWBX 3IOQA 3IUTA 3OISA 2FO5A 1CSBB 3WXFA 3PW3A 2NQAA 3MORA 2XU3A 3RVVA 4MZSA 3OVZA 2FUDA 1AU4A 1MDWA 3M99A 1AYWA 1AECA 3BPMA 3I3TA 3C9EA 1QMYA 3H8CA 3HWNA 2DC6A 1PPDA 3CH2X 1TL9A 5CHVA 5EGWA 3HHAA 2AUXA 3IHPA 1ME3A 5CVOB 4CZWA 1PXVA 2E03A 1BQIA 3S3RA 7PCKA 4I04A 2IPPB 2Y5BA 1AYUA 1PE6A 3KWZA 3AI8A 4YYSA 4W5BA 3E1ZB 2P7UA 2R9CA 3IEJA 4PI3A 4X6IA 3H8BA 2XU4A 4CDDB 1A6RA 3K9MA 1GECE 3BOWA 1U9QX 1PCIA 2DZZA 3QSDA 1EWPA 2R9NA 1KFUL 2ACTA 1YALA 3OF8A 1U5IA 2FRAA 2PADA 3DF0A 4PP1A 2PREA 1FH0A 2NQDB 2P0RA 5FPWA 4W5CA 1QOLA 3H89A 2C0YA 2GHUA 1ZCMA 2DJFB 4KLBA 1AYVA 1DF0A 2Y6EA 1JQPA 1Y08A 3O0UA 2DJGB 3PNRA 1SNKA 2HH5A 4DMXA 4OEMA 9PAPA 3P5VA 4MZOA 2NQGA 2G7YA 2BDZA 4QRVA 3QT4A 3NHEA 3CBJA 1BGOA 4WA6A 2AIMA 2AVWA 2YJ8A 1MIRA 2FT2A 4N79A 5CVMA 4BSQA 1AU2A 3PDFA 1F2AA 2R6NA 2GFOA 1TLOA 2R9FA 2CIOA 1S4VA 1CQDA 4ZUXU 4YYRA 4DMYA 4K7CA 3P5UA 1VSNA 2XU1A 5PADA 4BS5A 4Q8HA 2OZ2A 4XUIA 3HD3A 1MEGA 5JH3A 1EWLA 3KKUA 1F2CA 3H6SA 3S3QA 1EWMA 2DC9A 6PADA 1U9VA 2JQGR 4QRXA 2B1MA 4P6GA 2P86A 1X9YA 1PPNA 2YJCA 3B79A 1XKGA 2E00A 5K16A 3F75A 3MHSA 1BY8A 1MHWA 1NB5A 1CJLA 1Q6KA 1ZIVA 1ATKA 1ITOA 3WXEA 2AS8A 4YV8A 3K24A 3OVXA 1CTEA 4FIPA 3QJ3A 2YJBA 5JA7A 4N4ZA 1NLJA 2E01A 2XU5A 3MTNA 3H7DA 3ZUAA 4PADA 2R9OA 1F29A 4X6JA 4Q8GA 1K3BB 1YVBA 2FRQA 3KSEA 1GLOA 2DCCA 2G6DA 5CVNB 1MEMA 2YJ9A 1PBHA 3PBHA 4XR7A 1F2BA 3I06A 3CH3X 2JQFR 1VJVA 2HHNA 2DCBA 4BPVA 1CPJA 1ICFA 3U8EA 2DC7A 3MHHA 2CB5A 1GMYA 3RVWA 2AYOA 2OP3A 3KW9A 3BWKA 4W4UA 4MSXA 2B1NA 4PP2E 8PCHA 3USVA 1CS8A 4QBBA 1KHQA 3RVXA 2F1GA 3BC3A 4X6HA 3WXGA 2FTDA 4QH6A 2NQIA 1NL6A 4RY2A 4YVAA 2PBHA 4FK5A 4CDFB 4I07A 3IV2A 3P5XA 2E02A 3LXSA 2AUZA 4BS6A 1YK7A 3BCNA 4HWYA 3K8UA 2F7DA 4OELA 1QXPA 1PADA 1NQCA 2R9MA 2FYEA 1KHPA 2ARYA 3KFQA 2IBIA 1DEUA 4YYQA 3O1GA 1EWOA 2WBFX 5EF4A 3HHIA 1BP4A 1QDQA 1YK8A 3V6EA 4QRGA 3V6CA 2G8EA 3N3KA 2DCDA 2DC8A 4YYWA 2AYNA 2AU1A 2VHSA 1CVZA 3KX1A
chains in the Genus database with same CATH superfamily
3LFYA 4N8WA 3N3GA 5A24A 2YJ2A 1YT7A 1MS6A 3P5WA 2DCAA 2G8JA 1IWDA 5EZSA 4RF1A 1HUCB 2BDLA 2HD5A 5CHTA 5EZQA 4D8IA 4BOPA 2VHFA 3OF9A 4BQVA 1EF7A 1KXRA 2BTWA 4P6EA 3PSEA 4YYVA 1Y4HA 5F02A 3TMPA 4YYUA 2HXZA 1NPZA 1O0EA 4CDCB 2ATOA 1PPPA 2BTWB 1KFXL 2FQ9A 2PNSA 1CB5A 3ERVA 1POPA 5J94A 2JRIA 3MJ5A 3TNXA 4AXMA 1AIMA 3BPFA 4FJCA 3IMAA 4I05A 3D6SA 1U9XA 3F5VA 4M0WA 3CBKA 1ME4A 1PIPA 4AXLA 4MI7A 3N4CA 4BOUA 4G54A 2DZYA 1U9WA 3GCBA 1STFE 2H7JA 1NB3A 1M6DA 1THEA 1SP4B 2UZJA 1TU6A 1CV8A 1AU3A 2O6XA 2OULA 1GCBA 1PPOA 1AU0A 4MM3B 4CDEB 3KWBX 3IOQA 3IUTA 3OISA 2FO5A 1CSBB 3MP2A 3WXFA 4WURA 3PW3A 2NQAA 2Z84A 3MORA 2XU3A 3RVVA 4MZSA 3W30A 3OVZA 2FUDA 1AU4A 1MDWA 3M99A 1AYWA 2J7QC 1AECA 3BPMA 3I3TA 3C9EA 3PT2A 1QMYA 3H8CA 5JZEA 3HWNA 2DC6A 1PPDA 3CH2X 1TL9A 5CHVA 5EGWA 3HHAA 2AUXA 2FE8A 3IHPA 1ME3A 5CVOB 4CZWA 1PXVA 2E03A 1BQIA 3S3RA 7PCKA 4I04A 2IPPB 4A5UA 2Y5BA 1AYUA 1PE6A 3BB7A 3KWZA 3AI8A 4YYSA 4W5BA 3RNVA 3E1ZB 2P7UA 4P16A 2R9CA 3IEJA 4PI3A 4BOZA 4X6IA 3H8BA 2XU4A 4OW0A 1A6RA 3K9MA 4CDDB 1GECE 3BOWA 1U9QX 4RKXA 3BY4A 1PCIA 2DZZA 3PHWA 3QSDA 1EWPA 2R9NA 1KFUL 2ACTA 1YALA 3OF8A 1U5IA 2FRAA 2PADA 3DF0A 4PP1A 2PREA 1FH0A 2NQDB 2P0RA 5FPWA 4W5CA 1QOLA 3H89A 2C0YA 2DOSA 1ZCMA 2GHUA 2DJFB 4KLBA 4IP3A 1AYVA 1DF0A 2Y6EA 1JQPA 1Y08A 1DKIA 4RF0A 3O0UA 2DJGB 3PNRA 1SNKA 2HH5A 4DMXA 4OEMA 9PAPA 3P5VA 4MZOA 2NQGA 2G7YA 2BU3A 2BDZA 3C0RA 4QRVA 3QT4A 3NHEA 3CBJA 1BGOA 4R3DA 4WA6A 2AIMA 2AVWA 2YJ8A 1MIRA 2FT2A 4N79A 4BOQA 5CVMA 4BSQA 3IFUA 3B21A 1AU2A 3PDFA 3PRPA 1F2AA 2R6NA 2GFOA 3OQCA 1TLOA 2R9FA 3PRMA 2CIOA 1S4VA 1CQDA 3ZNHA 4ZUXU 2J7QA 4YYRA 4DMYA 2JTCA 4K7CA 3P5UA 1VSNA 2XU1A 5PADA 4BS5A 4Q8HA 2OZ2A 4XUIA 3HD3A 1MEGA 5JH3A 1EWLA 3KKUA 1F2CA 3H6SA 3S3QA 1EWMA 2DC9A 6PADA 1U9VA 2JQGR 4QRXA 2B1MA 5KO3A 4P6GA 2P86A 1X9YA 1PPNA 2YJCA 3B79A 1XKGA 2E00A 1UKFA 5K16A 3F75A 3MHSA 1BY8A 1MHWA 1NB5A 1CJLA 1Q6KA 1ZIVA 4OVZB 1ATKA 1ITOA 3W31A 3WXEA 2AS8A 5E6JA 4YV8A 4PT5A 4REZA 3K24A 3OVXA 1CTEA 3PHUA 3BBAA 4FIPA 4GUAA 4XZXA 3QJ3A 2YJBA 5JA7A 4N4ZA 1NLJA 4IUMA 2E01A 2XU5A 4ZTBA 3MTNA 3H7DA 3ZUAA 4PADA 2R9OA 1F29A 4X6JA 4D8EA 4Q8GA 1K3BB 1YVBA 2FRQA 3KSEA 1GLOA 2DCCA 2G6DA 5CVNB 4D8BA 1MEMA 2YJ9A 1PBHA 3PBHA 4XR7A 1F2BA 3I06A 3CH3X 2JQFR 1VJVA 2HHNA 2DCBA 4RNAA 4BPVA 1CPJA 1ICFA 3U8EA 2DC7A 3MHHA 2CB5A 1GMYA 3RVWA 2AYOA 2OP3A 3KW9A 3BWKA 4W4UA 4MSXA 2B1NA 4PP2E 8PCHA 3O65A 3USVA 1CS8A 4QBBA 1KHQA 3RVXA 2F1GA 3BC3A 4X6HA 3WXGA 2FTDA 4QH6A 2NQIA 3E9SA 1NL6A 4RY2A 4YVAA 2PBHA 4FK5A 4CDFB 4OVZA 4HXDB 4I07A 3IV2A 3P5XA 3TRKA 2E02A 3LXSA 2AUZA 4BS6A 1YK7A 3BCNA 4HWYA 3K8UA 2F7DA 4OELA 1QXPA 1PADA 1PVJA 1NQCA 2R9MA 2FYEA 1KHPA 2ARYA 3KFQA 2IBIA 1DEUA 4YYQA 3O1GA 1EWOA 2WBFX 5EF4A 3HHIA 3PHXA 1BP4A 1QDQA 1YK8A 3V6EA 4QRGA 4BOSA 1YZBA 3V6CA 2G8EA 3MTVA 2AGAA 3N3KA 2DCDA 2DC8A 4YYWA 2AYNA 2AU1A 2VHSA 2HWKA 1CVZA 3KX1A
chains in the Genus database with same CATH topology
3LFYA 4N8WA 3N3GA 5A24A 2YJ2A 1YT7A 1MS6A 3P5WA 2DCAA 2G8JA 4BGFA 1IWDA 1HUCB 2BDLA 2HD5A 5CHTA 2VHFA 3OF9A 4BQVA 1EF7A 1KXRA 4P6EA 4YYVA 1Y4HA 5F02A 4YYUA 2HXZA 1NPZA 1O0EA 4CDCB 2ATOA 1PPPA 1KFXL 2VFBA 2FQ9A 2PNSA 1CB5A 3ERVA 1POPA 5J94A 3TNXA 4AXMA 1AIMA 3BPFA 4FJCA 3IMAA 4I05A 3D6SA 1U9XA 3F5VA 3CBKA 1ME4A 1PIPA 4AXLA 3N4CA 4G54A 2DZYA 1U9WA 3GCBA 1STFE 2H7JA 1NB3A 1M6DA 1THEA 1E2TA 1SP4B 1TU6A 1CV8A 1AU3A 2O6XA 2OULA 1GCBA 1PPOA 1AU0A 4B55A 4CDEB 3KWBX 3IOQA 3IUTA 3OISA 2FO5A 1CSBB 3WXFA 3PW3A 2NQAA 3MORA 2XU3A 3RVVA 4MZSA 3OVZA 2FUDA 1AU4A 1MDWA 3M99A 1W5RA 1AYWA 1AECA 3BPMA 3I3TA 3C9EA 2BSZA 1QMYA 3H8CA 3HWNA 2DC6A 1PPDA 3CH2X 1TL9A 5CHVA 5EGWA 3HHAA 2AUXA 3IHPA 1ME3A 5CVOB 1GX3A 4CZWA 1PXVA 2E03A 1BQIA 3S3RA 7PCKA 4I04A 2IPPB 2Y5BA 1AYUA 1PE6A 3KWZA 3AI8A 4YYSA 4W5BA 3E1ZB 2P7UA 2R9CA 3IEJA 4PI3A 4X6IA 3H8BA 2XU4A 4CDDB 1A6RA 3K9MA 1GECE 3BOWA 1U9QX 1PCIA 2DZZA 2VFCA 3QSDA 1EWPA 2R9NA 1KFUL 2ACTA 1YALA 3OF8A 1U5IA 2FRAA 2PADA 3DF0A 4PP1A 2PREA 1FH0A 2NQDB 2P0RA 5FPWA 3LTWA 4W5CA 1QOLA 3H89A 2C0YA 2GHUA 1ZCMA 2DJFB 4KLBA 1AYVA 1DF0A 1W6FA 2Y6EA 1JQPA 1Y08A 3O0UA 2DJGB 3PNRA 1SNKA 2HH5A 4DMXA 4OEMA 9PAPA 3P5VA 4MZOA 2NQGA 2G7YA 2BDZA 4QRVA 3QT4A 3NHEA 3CBJA 1BGOA 4WA6A 2AIMA 2AVWA 2YJ8A 1MIRA 2FT2A 4N79A 5CVMA 4BSQA 4NV8A 1AU2A 3PDFA 1F2AA 2R6NA 2GFOA 1TLOA 2R9FA 2CIOA 1S4VA 1CQDA 4ZUXU 4YYRA 4DMYA 4K7CA 3P5UA 1VSNA 2XU1A 5PADA 4BS5A 4Q8HA 2OZ2A 4XUIA 3HD3A 1MEGA 5JH3A 1EWLA 3KKUA 1F2CA 3H6SA 3S3QA 1EWMA 2DC9A 6PADA 1U9VA 2JQGR 4QRXA 2B1MA 4P6GA 2P86A 1X9YA 1PPNA 2YJCA 3B79A 1XKGA 2E00A 5K16A 3F75A 3MHSA 1BY8A 1MHWA 1NB5A 1CJLA 1Q6KA 1ZIVA 1ATKA 1ITOA 3WXEA 2AS8A 4YV8A 3K24A 3OVXA 1CTEA 4FIPA 3QJ3A 2YJBA 5JA7A 4N4ZA 1NLJA 2E01A 2XU5A 3MTNA 3H7DA 3ZUAA 4PADA 2R9OA 1F29A 4X6JA 4GUZA 4Q8GA 1K3BB 1YVBA 2FRQA 3KSEA 1GLOA 2DCCA 2G6DA 5CVNB 1MEMA 2YJ9A 1PBHA 3PBHA 4XR7A 1F2BA 3I06A 3CH3X 2JQFR 1VJVA 2HHNA 2DCBA 4BPVA 4C5PA 1CPJA 1ICFA 3U8EA 2DC7A 3MHHA 2CB5A 1GMYA 3RVWA 2AYOA 2OP3A 3KW9A 3BWKA 4W4UA 4MSXA 2B1NA 4PP2E 8PCHA 3USVA 1CS8A 4QBBA 1KHQA 3RVXA 2F1GA 3BC3A 1W4TA 4X6HA 3WXGA 2FTDA 4QH6A 2NQIA 1NL6A 4RY2A 4YVAA 2PBHA 4FK5A 4CDFB 4I07A 3IV2A 3P5XA 2E02A 3LXSA 2AUZA 4BS6A 1YK7A 3BCNA 4HWYA 3K8UA 2F7DA 4OELA 1QXPA 1PADA 1NQCA 2R9MA 2FYEA 1KHPA 2ARYA 3KFQA 2IBIA 1DEUA 4YYQA 4NV7A 3O1GA 1EWOA 2WBFX 5EF4A 3HHIA 1BP4A 1QDQA 1YK8A 3D9WA 3V6EA 4QRGA 3V6CA 2G8EA 3N3KA 2DCDA 2DC8A 4YYWA 2AYNA 2AU1A 2VHSA 1CVZA 3KX1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LFY A;  4N8W A;  3N3G A;  5A24 A;  2YJ2 A;  1YT7 A;  1MS6 A;  3P5W A;  2DCA A;  2G8J A;  1IWD A;  1HUC B;  2BDL A;  2HD5 A;  5CHT A;  2VHF A;  3OF9 A;  4BQV A;  1EF7 A;  1KXR A;  4P6E A;  4YYV A;  1Y4H A;  5F02 A;  4YYU A;  2HXZ A;  1NPZ A;  1O0E A;  4CDC B;  2ATO A;  1PPP A;  1KFX L;  2FQ9 A;  2PNS A;  1CB5 A;  3ERV A;  1POP A;  5J94 A;  3TNX A;  4AXM A;  1AIM A;  3BPF A;  4FJC A;  3IMA A;  4I05 A;  3D6S A;  1U9X A;  3F5V A;  3CBK A;  1ME4 A;  1PIP A;  4AXL A;  3N4C A;  4G54 A;  2DZY A;  1U9W A;  3GCB A;  1STF E;  2H7J A;  1NB3 A;  1M6D A;  1THE A;  1SP4 B;  1TU6 A;  1CV8 A;  1AU3 A;  2O6X A;  2OUL A;  1GCB A;  1PPO A;  1AU0 A;  4CDE B;  3KWB X;  3IOQ A;  3IUT A;  3OIS A;  2FO5 A;  1CSB B;  3WXF A;  3PW3 A;  2NQA A;  3MOR A;  2XU3 A;  3RVV A;  4MZS A;  3OVZ A;  2FUD A;  1AU4 A;  1MDW A;  3M99 A;  1AYW A;  1AEC A;  3BPM A;  3I3T A;  3C9E A;  1QMY A;  3H8C A;  3HWN A;  2DC6 A;  1PPD A;  3CH2 X;  1TL9 A;  5CHV A;  5EGW A;  3HHA A;  2AUX A;  3IHP A;  1ME3 A;  5CVO B;  4CZW A;  1PXV A;  2E03 A;  1BQI A;  3S3R A;  7PCK A;  4I04 A;  2IPP B;  2Y5B A;  1AYU A;  1PE6 A;  3KWZ A;  3AI8 A;  4YYS A;  4W5B A;  3E1Z B;  2P7U A;  2R9C A;  3IEJ A;  4PI3 A;  4X6I A;  3H8B A;  2XU4 A;  4CDD B;  1A6R A;  3K9M A;  1GEC E;  3BOW A;  1U9Q X;  1PCI A;  2DZZ A;  3QSD A;  1EWP A;  2R9N A;  1KFU L;  2ACT A;  1YAL A;  3OF8 A;  1U5I A;  2FRA A;  2PAD A;  3DF0 A;  4PP1 A;  2PRE A;  1FH0 A;  2NQD B;  2P0R A;  5FPW A;  4W5C A;  1QOL A;  3H89 A;  2C0Y A;  2GHU A;  1ZCM A;  2DJF B;  4KLB A;  1AYV A;  1DF0 A;  2Y6E A;  1JQP A;  1Y08 A;  3O0U A;  2DJG B;  3PNR A;  1SNK A;  2HH5 A;  4DMX A;  4OEM A;  9PAP A;  3P5V A;  4MZO A;  2NQG A;  2G7Y A;  2BDZ A;  4QRV A;  3QT4 A;  3NHE A;  3CBJ A;  1BGO A;  4WA6 A;  2AIM A;  2AVW A;  2YJ8 A;  1MIR A;  2FT2 A;  4N79 A;  5CVM A;  4BSQ A;  1AU2 A;  3PDF A;  1F2A A;  2R6N A;  2GFO A;  1TLO A;  2R9F A;  2CIO A;  1S4V A;  1CQD A;  4ZUX U;  4YYR A;  4DMY A;  4K7C A;  3P5U A;  1VSN A;  2XU1 A;  5PAD A;  4BS5 A;  4Q8H A;  2OZ2 A;  4XUI A;  3HD3 A;  1MEG A;  5JH3 A;  1EWL A;  3KKU A;  1F2C A;  3H6S A;  3S3Q A;  1EWM A;  2DC9 A;  6PAD A;  1U9V A;  2JQG R;  4QRX A;  2B1M A;  4P6G A;  2P86 A;  1X9Y A;  1PPN A;  2YJC A;  3B79 A;  1XKG A;  2E00 A;  5K16 A;  3F75 A;  3MHS A;  1BY8 A;  1MHW A;  1NB5 A;  1CJL A;  1Q6K A;  1ZIV A;  1ATK A;  1ITO A;  3WXE A;  2AS8 A;  4YV8 A;  3K24 A;  3OVX A;  1CTE A;  4FIP A;  3QJ3 A;  2YJB A;  5JA7 A;  4N4Z A;  1NLJ A;  2E01 A;  2XU5 A;  3MTN A;  3H7D A;  3ZUA A;  4PAD A;  2R9O A;  1F29 A;  4X6J A;  4Q8G A;  1K3B B;  1YVB A;  2FRQ A;  3KSE A;  1GLO A;  2DCC A;  2G6D A;  5CVN B;  1MEM A;  2YJ9 A;  1PBH A;  3PBH A;  4XR7 A;  1F2B A;  3I06 A;  3CH3 X;  2JQF R;  1VJV A;  2HHN A;  2DCB A;  4BPV A;  1CPJ A;  1ICF A;  3U8E A;  2DC7 A;  3MHH A;  2CB5 A;  1GMY A;  3RVW A;  2AYO A;  2OP3 A;  3KW9 A;  3BWK A;  4W4U A;  4MSX A;  2B1N A;  4PP2 E;  8PCH A;  3USV A;  1CS8 A;  4QBB A;  1KHQ A;  3RVX A;  2F1G A;  3BC3 A;  4X6H A;  3WXG A;  2FTD A;  4QH6 A;  2NQI A;  1NL6 A;  4RY2 A;  4YVA A;  2PBH A;  4FK5 A;  4CDF B;  4I07 A;  3IV2 A;  3P5X A;  2E02 A;  3LXS A;  2AUZ A;  4BS6 A;  1YK7 A;  3BCN A;  4HWY A;  3K8U A;  2F7D A;  4OEL A;  1QXP A;  1PAD A;  1NQC A;  2R9M A;  2FYE A;  1KHP A;  2ARY A;  3KFQ A;  2IBI A;  1DEU A;  4YYQ A;  3O1G A;  1EWO A;  2WBF X;  5EF4 A;  3HHI A;  1BP4 A;  1QDQ A;  1YK8 A;  3V6E A;  4QRG A;  3V6C A;  2G8E A;  3N3K A;  2DCD A;  2DC8 A;  4YYW A;  2AYN A;  2AU1 A;  2VHS A;  1CVZ A;  3KX1 A; 
#chains in the Genus database with same CATH topology
 3LFY A;  4N8W A;  3N3G A;  5A24 A;  2YJ2 A;  1YT7 A;  1MS6 A;  3P5W A;  2DCA A;  2G8J A;  1IWD A;  5EZS A;  4RF1 A;  1HUC B;  2BDL A;  2HD5 A;  5CHT A;  5EZQ A;  4D8I A;  4BOP A;  2VHF A;  3OF9 A;  4BQV A;  1EF7 A;  1KXR A;  2BTW A;  4P6E A;  3PSE A;  4YYV A;  1Y4H A;  5F02 A;  3TMP A;  4YYU A;  2HXZ A;  1NPZ A;  1O0E A;  4CDC B;  2ATO A;  1PPP A;  2BTW B;  1KFX L;  2FQ9 A;  2PNS A;  1CB5 A;  3ERV A;  1POP A;  5J94 A;  2JRI A;  3MJ5 A;  3TNX A;  4AXM A;  1AIM A;  3BPF A;  4FJC A;  3IMA A;  4I05 A;  3D6S A;  1U9X A;  3F5V A;  4M0W A;  3CBK A;  1ME4 A;  1PIP A;  4AXL A;  4MI7 A;  3N4C A;  4BOU A;  4G54 A;  2DZY A;  1U9W A;  3GCB A;  1STF E;  2H7J A;  1NB3 A;  1M6D A;  1THE A;  1SP4 B;  2UZJ A;  1TU6 A;  1CV8 A;  1AU3 A;  2O6X A;  2OUL A;  1GCB A;  1PPO A;  1AU0 A;  4MM3 B;  4CDE B;  3KWB X;  3IOQ A;  3IUT A;  3OIS A;  2FO5 A;  1CSB B;  3MP2 A;  3WXF A;  4WUR A;  3PW3 A;  2NQA A;  2Z84 A;  3MOR A;  2XU3 A;  3RVV A;  4MZS A;  3W30 A;  3OVZ A;  2FUD A;  1AU4 A;  1MDW A;  3M99 A;  1AYW A;  2J7Q C;  1AEC A;  3BPM A;  3I3T A;  3C9E A;  3PT2 A;  1QMY A;  3H8C A;  5JZE A;  3HWN A;  2DC6 A;  1PPD A;  3CH2 X;  1TL9 A;  5CHV A;  5EGW A;  3HHA A;  2AUX A;  2FE8 A;  3IHP A;  1ME3 A;  5CVO B;  4CZW A;  1PXV A;  2E03 A;  1BQI A;  3S3R A;  7PCK A;  4I04 A;  2IPP B;  4A5U A;  2Y5B A;  1AYU A;  1PE6 A;  3BB7 A;  3KWZ A;  3AI8 A;  4YYS A;  4W5B A;  3RNV A;  3E1Z B;  2P7U A;  4P16 A;  2R9C A;  3IEJ A;  4PI3 A;  4BOZ A;  4X6I A;  3H8B A;  2XU4 A;  4OW0 A;  1A6R A;  3K9M A;  4CDD B;  1GEC E;  3BOW A;  1U9Q X;  4RKX A;  3BY4 A;  1PCI A;  2DZZ A;  3PHW A;  3QSD A;  1EWP A;  2R9N A;  1KFU L;  2ACT A;  1YAL A;  3OF8 A;  1U5I A;  2FRA A;  2PAD A;  3DF0 A;  4PP1 A;  2PRE A;  1FH0 A;  2NQD B;  2P0R A;  5FPW A;  4W5C A;  1QOL A;  3H89 A;  2C0Y A;  2DOS A;  1ZCM A;  2GHU A;  2DJF B;  4KLB A;  4IP3 A;  1AYV A;  1DF0 A;  2Y6E A;  1JQP A;  1Y08 A;  1DKI A;  4RF0 A;  3O0U A;  2DJG B;  3PNR A;  1SNK A;  2HH5 A;  4DMX A;  4OEM A;  9PAP A;  3P5V A;  4MZO A;  2NQG A;  2G7Y A;  2BU3 A;  2BDZ A;  3C0R A;  4QRV A;  3QT4 A;  3NHE A;  3CBJ A;  1BGO A;  4R3D A;  4WA6 A;  2AIM A;  2AVW A;  2YJ8 A;  1MIR A;  2FT2 A;  4N79 A;  4BOQ A;  5CVM A;  4BSQ A;  3IFU A;  3B21 A;  1AU2 A;  3PDF A;  3PRP A;  1F2A A;  2R6N A;  2GFO A;  3OQC A;  1TLO A;  2R9F A;  3PRM A;  2CIO A;  1S4V A;  1CQD A;  3ZNH A;  4ZUX U;  2J7Q A;  4YYR A;  4DMY A;  2JTC A;  4K7C A;  3P5U A;  1VSN A;  2XU1 A;  5PAD A;  4BS5 A;  4Q8H A;  2OZ2 A;  4XUI A;  3HD3 A;  1MEG A;  5JH3 A;  1EWL A;  3KKU A;  1F2C A;  3H6S A;  3S3Q A;  1EWM A;  2DC9 A;  6PAD A;  1U9V A;  2JQG R;  4QRX A;  2B1M A;  5KO3 A;  4P6G A;  2P86 A;  1X9Y A;  1PPN A;  2YJC A;  3B79 A;  1XKG A;  2E00 A;  1UKF A;  5K16 A;  3F75 A;  3MHS A;  1BY8 A;  1MHW A;  1NB5 A;  1CJL A;  1Q6K A;  1ZIV A;  4OVZ B;  1ATK A;  1ITO A;  3W31 A;  3WXE A;  2AS8 A;  5E6J A;  4YV8 A;  4PT5 A;  4REZ A;  3K24 A;  3OVX A;  1CTE A;  3PHU A;  3BBA A;  4FIP A;  4GUA A;  4XZX A;  3QJ3 A;  2YJB A;  5JA7 A;  4N4Z A;  1NLJ A;  4IUM A;  2E01 A;  2XU5 A;  4ZTB A;  3MTN A;  3H7D A;  3ZUA A;  4PAD A;  2R9O A;  1F29 A;  4X6J A;  4D8E A;  4Q8G A;  1K3B B;  1YVB A;  2FRQ A;  3KSE A;  1GLO A;  2DCC A;  2G6D A;  5CVN B;  4D8B A;  1MEM A;  2YJ9 A;  1PBH A;  3PBH A;  4XR7 A;  1F2B A;  3I06 A;  3CH3 X;  2JQF R;  1VJV A;  2HHN A;  2DCB A;  4RNA A;  4BPV A;  1CPJ A;  1ICF A;  3U8E A;  2DC7 A;  3MHH A;  2CB5 A;  1GMY A;  3RVW A;  2AYO A;  2OP3 A;  3KW9 A;  3BWK A;  4W4U A;  4MSX A;  2B1N A;  4PP2 E;  8PCH A;  3O65 A;  3USV A;  1CS8 A;  4QBB A;  1KHQ A;  3RVX A;  2F1G A;  3BC3 A;  4X6H A;  3WXG A;  2FTD A;  4QH6 A;  2NQI A;  3E9S A;  1NL6 A;  4RY2 A;  4YVA A;  2PBH A;  4FK5 A;  4CDF B;  4OVZ A;  4HXD B;  4I07 A;  3IV2 A;  3P5X A;  3TRK A;  2E02 A;  3LXS A;  2AUZ A;  4BS6 A;  1YK7 A;  3BCN A;  4HWY A;  3K8U A;  2F7D A;  4OEL A;  1QXP A;  1PAD A;  1PVJ A;  1NQC A;  2R9M A;  2FYE A;  1KHP A;  2ARY A;  3KFQ A;  2IBI A;  1DEU A;  4YYQ A;  3O1G A;  1EWO A;  2WBF X;  5EF4 A;  3HHI A;  3PHX A;  1BP4 A;  1QDQ A;  1YK8 A;  3V6E A;  4QRG A;  4BOS A;  1YZB A;  3V6C A;  2G8E A;  3MTV A;  2AGA A;  3N3K A;  2DCD A;  2DC8 A;  4YYW A;  2AYN A;  2AU1 A;  2VHS A;  2HWK A;  1CVZ A;  3KX1 A; 
#chains in the Genus database with same CATH homology
 3LFY A;  4N8W A;  3N3G A;  5A24 A;  2YJ2 A;  1YT7 A;  1MS6 A;  3P5W A;  2DCA A;  2G8J A;  4BGF A;  1IWD A;  1HUC B;  2BDL A;  2HD5 A;  5CHT A;  2VHF A;  3OF9 A;  4BQV A;  1EF7 A;  1KXR A;  4P6E A;  4YYV A;  1Y4H A;  5F02 A;  4YYU A;  2HXZ A;  1NPZ A;  1O0E A;  4CDC B;  2ATO A;  1PPP A;  1KFX L;  2VFB A;  2FQ9 A;  2PNS A;  1CB5 A;  3ERV A;  1POP A;  5J94 A;  3TNX A;  4AXM A;  1AIM A;  3BPF A;  4FJC A;  3IMA A;  4I05 A;  3D6S A;  1U9X A;  3F5V A;  3CBK A;  1ME4 A;  1PIP A;  4AXL A;  3N4C A;  4G54 A;  2DZY A;  1U9W A;  3GCB A;  1STF E;  2H7J A;  1NB3 A;  1M6D A;  1THE A;  1E2T A;  1SP4 B;  1TU6 A;  1CV8 A;  1AU3 A;  2O6X A;  2OUL A;  1GCB A;  1PPO A;  1AU0 A;  4B55 A;  4CDE B;  3KWB X;  3IOQ A;  3IUT A;  3OIS A;  2FO5 A;  1CSB B;  3WXF A;  3PW3 A;  2NQA A;  3MOR A;  2XU3 A;  3RVV A;  4MZS A;  3OVZ A;  2FUD A;  1AU4 A;  1MDW A;  3M99 A;  1W5R A;  1AYW A;  1AEC A;  3BPM A;  3I3T A;  3C9E A;  2BSZ A;  1QMY A;  3H8C A;  3HWN A;  2DC6 A;  1PPD A;  3CH2 X;  1TL9 A;  5CHV A;  5EGW A;  3HHA A;  2AUX A;  3IHP A;  1ME3 A;  5CVO B;  1GX3 A;  4CZW A;  1PXV A;  2E03 A;  1BQI A;  3S3R A;  7PCK A;  4I04 A;  2IPP B;  2Y5B A;  1AYU A;  1PE6 A;  3KWZ A;  3AI8 A;  4YYS A;  4W5B A;  3E1Z B;  2P7U A;  2R9C A;  3IEJ A;  4PI3 A;  4X6I A;  3H8B A;  2XU4 A;  4CDD B;  1A6R A;  3K9M A;  1GEC E;  3BOW A;  1U9Q X;  1PCI A;  2DZZ A;  2VFC A;  3QSD A;  1EWP A;  2R9N A;  1KFU L;  2ACT A;  1YAL A;  3OF8 A;  1U5I A;  2FRA A;  2PAD A;  3DF0 A;  4PP1 A;  2PRE A;  1FH0 A;  2NQD B;  2P0R A;  5FPW A;  3LTW A;  4W5C A;  1QOL A;  3H89 A;  2C0Y A;  2GHU A;  1ZCM A;  2DJF B;  4KLB A;  1AYV A;  1DF0 A;  1W6F A;  2Y6E A;  1JQP A;  1Y08 A;  3O0U A;  2DJG B;  3PNR A;  1SNK A;  2HH5 A;  4DMX A;  4OEM A;  9PAP A;  3P5V A;  4MZO A;  2NQG A;  2G7Y A;  2BDZ A;  4QRV A;  3QT4 A;  3NHE A;  3CBJ A;  1BGO A;  4WA6 A;  2AIM A;  2AVW A;  2YJ8 A;  1MIR A;  2FT2 A;  4N79 A;  5CVM A;  4BSQ A;  4NV8 A;  1AU2 A;  3PDF A;  1F2A A;  2R6N A;  2GFO A;  1TLO A;  2R9F A;  2CIO A;  1S4V A;  1CQD A;  4ZUX U;  4YYR A;  4DMY A;  4K7C A;  3P5U A;  1VSN A;  2XU1 A;  5PAD A;  4BS5 A;  4Q8H A;  2OZ2 A;  4XUI A;  3HD3 A;  1MEG A;  5JH3 A;  1EWL A;  3KKU A;  1F2C A;  3H6S A;  3S3Q A;  1EWM A;  2DC9 A;  6PAD A;  1U9V A;  2JQG R;  4QRX A;  2B1M A;  4P6G A;  2P86 A;  1X9Y A;  1PPN A;  2YJC A;  3B79 A;  1XKG A;  2E00 A;  5K16 A;  3F75 A;  3MHS A;  1BY8 A;  1MHW A;  1NB5 A;  1CJL A;  1Q6K A;  1ZIV A;  1ATK A;  1ITO A;  3WXE A;  2AS8 A;  4YV8 A;  3K24 A;  3OVX A;  1CTE A;  4FIP A;  3QJ3 A;  2YJB A;  5JA7 A;  4N4Z A;  1NLJ A;  2E01 A;  2XU5 A;  3MTN A;  3H7D A;  3ZUA A;  4PAD A;  2R9O A;  1F29 A;  4X6J A;  4GUZ A;  4Q8G A;  1K3B B;  1YVB A;  2FRQ A;  3KSE A;  1GLO A;  2DCC A;  2G6D A;  5CVN B;  1MEM A;  2YJ9 A;  1PBH A;  3PBH A;  4XR7 A;  1F2B A;  3I06 A;  3CH3 X;  2JQF R;  1VJV A;  2HHN A;  2DCB A;  4BPV A;  4C5P A;  1CPJ A;  1ICF A;  3U8E A;  2DC7 A;  3MHH A;  2CB5 A;  1GMY A;  3RVW A;  2AYO A;  2OP3 A;  3KW9 A;  3BWK A;  4W4U A;  4MSX A;  2B1N A;  4PP2 E;  8PCH A;  3USV A;  1CS8 A;  4QBB A;  1KHQ A;  3RVX A;  2F1G A;  3BC3 A;  1W4T A;  4X6H A;  3WXG A;  2FTD A;  4QH6 A;  2NQI A;  1NL6 A;  4RY2 A;  4YVA A;  2PBH A;  4FK5 A;  4CDF B;  4I07 A;  3IV2 A;  3P5X A;  2E02 A;  3LXS A;  2AUZ A;  4BS6 A;  1YK7 A;  3BCN A;  4HWY A;  3K8U A;  2F7D A;  4OEL A;  1QXP A;  1PAD A;  1NQC A;  2R9M A;  2FYE A;  1KHP A;  2ARY A;  3KFQ A;  2IBI A;  1DEU A;  4YYQ A;  4NV7 A;  3O1G A;  1EWO A;  2WBF X;  5EF4 A;  3HHI A;  1BP4 A;  1QDQ A;  1YK8 A;  3D9W A;  3V6E A;  4QRG A;  3V6C A;  2G8E A;  3N3K A;  2DCD A;  2DC8 A;  4YYW A;  2AYN A;  2AU1 A;  2VHS A;  1CVZ A;  3KX1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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