2YJCA

Cathepsin l with a nitrile inhibitor
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
220
structure length
219
Chain Sequence
b'APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTSDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords CATHEPSIN L1
publication title Halogen Bonding at the Active Sites of Human Cathepsin L and Mek1 Kinase: Efficient Interactions in Different Environments.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase
total genus 74
structure length 219
sequence length 220
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2011-05-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2yjcA00
1MEGA 4DMXA 2FRAA 4G54A 1YK8A 2VHSA 2H7JA 2FTDA 4PP1A 2F7DA 3MTNA 2YJ2A 3KWZA 3BOWA 5JH3A 2R9NA 2ACTA 1EWPA 3I3TA 2FUDA 2R9CA 3PBHA 1GMYA 3P5VA 4PI3A 2ATOA 2G6DA 2R6NA 4HWYA 1F2CA 5JA7A 4ZUXU 2BDLA 3HWNA 4X6JA 2GHUA 3S3QA 1TU6A 4BPVA 3CBKA 2P7UA 2O6XA 4I04A 3BCNA 4FK5A 3D6SA 2PBHA 3PNRA 4DMYA 1U5IA 1VSNA 5EF4A 3KKUA 1PBHA 1EWOA 1PE6A 3WXGA 2R9MA 2PNSA 1QXPA 5J94A 4Q8GA 4QRVA 5PADA 1PIPA 1CPJA 3LFYA 2DC8A 4BS5A 2AU1A 2OP3A 3S3RA 3OISA 1QDQA 1NLJA 3RVVA 3BPMA 1GLOA 5CHVA 4X6HA 2HD5A 3BPFA 3NHEA 5A24A 1BQIA 1XKGA 1Q6KA 1Y4HA 1CB5A 4I05A 2HHNA 2NQGA 1BGOA 3BWKA 2CIOA 3QJ3A 3ERVA 1GECE 1VJVA 3H8CA 3KW9A 1O0EA 2Y6EA 3C9EA 3V6CA 1EWMA 4I07A 1PPDA 2FQ9A 6PADA 3OVXA 3IOQA 1THEA 1PPNA 1A6RA 4QRGA 2CB5A 2DC7A 4N4ZA 4OELA 1KHPA 3IV2A 1CTEA 2OZ2A 1K3BB 1PXVA 2YJ9A 3ZUAA 4OEMA 4RY2A 3K9MA 3AI8A 1ME4A 3HD3A 3P5WA 4KLBA 1NL6A 4YYRA 4K7CA 3GCBA 1STFE 3MHSA 1YK7A 1AU4A 4P6EA 2DZZA 1HUCB 2AVWA 1DF0A 1MHWA 3OF9A 3PDFA 1GCBA 2AYNA 1ZCMA 4CDEB 1KXRA 5EGWA 2R9FA 1F2AA 1SNKA 3N3KA 3E1ZB 1MIRA 2XU5A 2PREA 2DCBA 2Y5BA 4W4UA 1AECA 1YVBA 3KSEA 1BY8A 4MZOA 2R9OA 2WBFX 4PADA 2YJ8A 1CSBB 2VHFA 2XU1A 1F2BA 1ATKA 2GFOA 3K24A 1AYVA 3IHPA 4CZWA 2AUXA 1CQDA 2DC9A 1ZIVA 5CVOB 4P6GA 3U8EA 1U9QX 4W5CA 4YYQA 2DJGB 1IWDA 1CVZA 1PADA 3MORA 3H7DA 4X6IA 4AXLA 1ITOA 1POPA 3TNXA 3IUTA 1BP4A 3HHAA 3F75A 1MS6A 2E01A 4MSXA 4CDFB 2DCCA 2AS8A 1NB5A 3KX1A 4QBBA 2IPPB 2OULA 2G8EA 2XU4A 2F1GA 4FJCA 4W5BA 2FO5A 3CH2X 2NQDB 3H6SA 1JQPA 2B1NA 3V6EA 2ARYA 4QRXA 4YVAA 2FYEA 1S4VA 4XR7A 2BDZA 3QT4A 3O0UA 1X9YA 3OVZA 1YT7A 1AU0A 2E02A 3K8UA 4CDCB 2HXZA 1ME3A 2DZYA 4YYUA 2B1MA 2DCAA 1AYWA 4YYWA 1NQCA 1U9XA 2C0YA 1Y08A 4YYVA 4XUIA 2HH5A 7PCKA 1AYUA 4Q8HA 3N4CA 1CV8A 1U9VA 2FRQA 2DJFB 1KFXL 3H8BA 5CHTA 3M99A 1YALA 3IEJA 5CVMA 4BQVA 2NQAA 1DEUA 4AXMA 5CVNB 3DF0A 2DCDA 3QSDA 4N8WA 8PCHA 2E00A 2NQIA 1CJLA 2AYOA 3WXEA 3HHIA 3F5VA 5FPWA 3USVA 1M6DA 3CH3X 4YYSA 1PPPA 3MHHA 5F02A 3O1GA 1SP4B 4MZSA 4BS6A 1MDWA 1QMYA 2AUZA 2G7YA 1PCIA 2PADA 2IBIA 1TLOA 1ICFA 4QH6A 2JQFR 3I06A 3PW3A 1AU3A 4WA6A 2YJBA 3LXSA 4N79A 4YV8A 1U9WA 3CBJA 1NB3A 2E03A 3P5XA 2JQGR 3N3GA 1NPZA 4CDDB 4BSQA 1KFUL 2G8JA 1AIMA 3RVXA 5K16A 1KHQA 1EWLA 2P0RA 1AU2A 1EF7A 1F29A 1MEMA 3WXFA 4FIPA 3BC3A 3IMAA 3H89A 3KWBX 1TL9A 1PPOA 2FT2A 1QOLA 2DC6A 3P5UA 9PAPA 2P86A 4PP2E 3RVWA 3KFQA 2AIMA 3OF8A 2XU3A 2YJCA 3B79A 1FH0A 1CS8A
chains in the Genus database with same CATH superfamily
1MEGA 4DMXA 2FRAA 4G54A 3PHWA 1YK8A 2VHSA 2H7JA 2FTDA 4MI7A 4PP1A 4REZA 2F7DA 3MTNA 2YJ2A 3KWZA 3BOWA 5JH3A 2R9NA 2ACTA 1EWPA 3I3TA 2FUDA 2R9CA 3PBHA 1GMYA 4OVZB 3P5VA 4PI3A 2ATOA 2G6DA 2R6NA 4HWYA 1F2CA 5JA7A 4ZUXU 2BDLA 4IP3A 2JRIA 3HWNA 4X6JA 2GHUA 3S3QA 1TU6A 4BPVA 3CBKA 2P7UA 2O6XA 5EZQA 4I04A 3BCNA 4FK5A 3W31A 3D6SA 2BU3A 2PBHA 3PNRA 4DMYA 1U5IA 1VSNA 5EF4A 3KKUA 1PBHA 1EWOA 1PE6A 3WXGA 3RNVA 2R9MA 2PNSA 1QXPA 5J94A 4Q8GA 4QRVA 5PADA 4BOPA 1PIPA 3BB7A 1CPJA 3LFYA 2DC8A 4BS5A 2AU1A 2OP3A 3S3RA 3OISA 1QDQA 5E6JA 1NLJA 3RVVA 3BPMA 1GLOA 5CHVA 4X6HA 2HD5A 4IUMA 3BPFA 4BOSA 3NHEA 5A24A 1BQIA 4M0WA 1XKGA 1Q6KA 1Y4HA 1CB5A 4I05A 2HHNA 2NQGA 1BGOA 2UZJA 5EZSA 1UKFA 3BWKA 2CIOA 3QJ3A 3ERVA 3TRKA 3C0RA 1GECE 1VJVA 2J7QA 3H8CA 3KW9A 1O0EA 2Y6EA 3PHUA 3C9EA 2DOSA 3V6CA 1EWMA 4I07A 1PPDA 2FQ9A 6PADA 3OVXA 3IOQA 1THEA 1PPNA 1A6RA 4QRGA 2CB5A 2DC7A 4N4ZA 4OELA 4PT5A 1KHPA 3B21A 1PVJA 3IV2A 1CTEA 2OZ2A 1K3BB 1PXVA 2YJ9A 3ZUAA 4OEMA 4RY2A 3E9SA 3K9MA 3AI8A 4BOZA 1ME4A 3W30A 3HD3A 3P5WA 4KLBA 1NL6A 4YYRA 4BOUA 4K7CA 3GCBA 1STFE 3MHSA 1YK7A 1AU4A 4RF0A 4P6EA 4WURA 2DZZA 1HUCB 2AVWA 1DF0A 3MTVA 1MHWA 2BTWA 3OF9A 3PDFA 4GUAA 1GCBA 2AYNA 1ZCMA 4CDEB 1KXRA 5EGWA 2R9FA 1F2AA 1SNKA 3N3KA 3E1ZB 1MIRA 2XU5A 5KO3A 2PREA 2DCBA 1YZBA 2Y5BA 4W4UA 1AECA 1YVBA 3KSEA 1BY8A 4P16A 4MZOA 2R9OA 2WBFX 4PADA 3TMPA 2YJ8A 1CSBB 2VHFA 2XU1A 1F2BA 1ATKA 2GFOA 5JZEA 3K24A 4RNAA 1AYVA 3IHPA 4CZWA 2AUXA 2Z84A 1CQDA 2DC9A 1ZIVA 5CVOB 4P6GA 3U8EA 1U9QX 4W5CA 4YYQA 3MJ5A 2DJGB 1IWDA 1CVZA 1PADA 4A5UA 2BTWB 3MORA 3H7DA 4X6IA 4AXLA 1ITOA 1POPA 3TNXA 3IUTA 1BP4A 3HHAA 3F75A 1MS6A 2E01A 4MSXA 4CDFB 2DCCA 2AS8A 4OW0A 1NB5A 4OVZA 3KX1A 4QBBA 2IPPB 2OULA 2G8EA 3ZNHA 2XU4A 2F1GA 4FJCA 4W5BA 2FO5A 3CH2X 2NQDB 3H6SA 1JQPA 2B1NA 3V6EA 3O65A 2ARYA 4QRXA 4YVAA 2FYEA 1S4VA 4XR7A 2J7QC 4RKXA 2HWKA 2BDZA 3QT4A 3O0UA 1X9YA 3OVZA 1YT7A 1AU0A 2E02A 3K8UA 4CDCB 2HXZA 1ME3A 2DZYA 4HXDB 4YYUA 3MP2A 2B1MA 2DCAA 1AYWA 4YYWA 1NQCA 1U9XA 2C0YA 1Y08A 4YYVA 4XUIA 2HH5A 7PCKA 1AYUA 1DKIA 4XZXA 4Q8HA 3N4CA 1CV8A 1U9VA 2FRQA 4D8EA 2DJFB 1KFXL 2FE8A 3IFUA 3H8BA 5CHTA 3M99A 3PRPA 1YALA 3IEJA 5CVMA 4BQVA 2NQAA 1DEUA 4MM3B 4AXMA 5CVNB 4BOQA 3DF0A 2DCDA 3QSDA 4N8WA 8PCHA 2E00A 2NQIA 1CJLA 2AYOA 3BY4A 3WXEA 3HHIA 3F5VA 3PSEA 5FPWA 3USVA 4D8IA 1M6DA 3CH3X 4YYSA 1PPPA 3MHHA 5F02A 3O1GA 1SP4B 4MZSA 3PHXA 1MDWA 1QMYA 2AUZA 4BS6A 2G7YA 1PCIA 2PADA 2IBIA 1TLOA 1ICFA 4QH6A 2JQFR 3I06A 4RF1A 3PRMA 3PW3A 1AU3A 4WA6A 2YJBA 2JTCA 3LXSA 4N79A 4YV8A 1U9WA 3CBJA 2AGAA 1NB3A 2E03A 3BBAA 3P5XA 2JQGR 3N3GA 1NPZA 4CDDB 4BSQA 1KFUL 2G8JA 1AIMA 3RVXA 5K16A 1KHQA 1EWLA 2P0RA 1AU2A 1EF7A 1F29A 1MEMA 3WXFA 4FIPA 3BC3A 3IMAA 3PT2A 3H89A 3KWBX 3OQCA 1TL9A 1PPOA 2FT2A 1QOLA 2DC6A 4ZTBA 3P5UA 9PAPA 2P86A 4PP2E 3RVWA 3KFQA 2AIMA 4D8BA 3OF8A 2XU3A 2YJCA 3B79A 1FH0A 1CS8A 4R3DA
chains in the Genus database with same CATH topology
1MEGA 4DMXA 2FRAA 4G54A 1YK8A 2VHSA 2H7JA 2FTDA 4NV7A 4PP1A 2F7DA 3MTNA 2YJ2A 3KWZA 3BOWA 5JH3A 2R9NA 2ACTA 1EWPA 3I3TA 2FUDA 2R9CA 3PBHA 1GMYA 3P5VA 4PI3A 2ATOA 2G6DA 2R6NA 4HWYA 1F2CA 5JA7A 4ZUXU 2BDLA 3HWNA 4X6JA 2GHUA 3S3QA 1TU6A 4BPVA 3CBKA 2P7UA 3D9WA 2O6XA 4I04A 3BCNA 4FK5A 3D6SA 2PBHA 3PNRA 4DMYA 1U5IA 1VSNA 5EF4A 3KKUA 1PBHA 1EWOA 1PE6A 3WXGA 2R9MA 2PNSA 1QXPA 5J94A 4Q8GA 4QRVA 5PADA 1PIPA 1CPJA 3LFYA 2DC8A 4BS5A 2AU1A 2OP3A 3S3RA 3OISA 1QDQA 1NLJA 3RVVA 3BPMA 1GLOA 5CHVA 4X6HA 2HD5A 3BPFA 3NHEA 5A24A 1BQIA 1XKGA 1Q6KA 1Y4HA 1CB5A 4I05A 2HHNA 2NQGA 1BGOA 3BWKA 2CIOA 3QJ3A 3ERVA 1GECE 1VJVA 3H8CA 3KW9A 1O0EA 2Y6EA 3C9EA 3V6CA 1EWMA 4I07A 1PPDA 2FQ9A 6PADA 3OVXA 3IOQA 1THEA 1PPNA 1A6RA 4QRGA 2CB5A 2DC7A 4N4ZA 4OELA 1KHPA 3IV2A 1CTEA 2OZ2A 1K3BB 1PXVA 2YJ9A 3ZUAA 4OEMA 4C5PA 4RY2A 3K9MA 3AI8A 1ME4A 3HD3A 3P5WA 4KLBA 1NL6A 4YYRA 4K7CA 1W6FA 3GCBA 1STFE 3MHSA 1YK7A 1AU4A 4P6EA 2DZZA 1HUCB 2AVWA 1DF0A 1MHWA 3OF9A 3PDFA 1GCBA 2AYNA 1ZCMA 4CDEB 1KXRA 5EGWA 2R9FA 1F2AA 1SNKA 3N3KA 3E1ZB 1MIRA 2XU5A 2PREA 2DCBA 2Y5BA 4W4UA 1AECA 1YVBA 3KSEA 1BY8A 4MZOA 2R9OA 2WBFX 4PADA 2YJ8A 1CSBB 2VHFA 2XU1A 1F2BA 1ATKA 2GFOA 3K24A 1AYVA 3IHPA 4CZWA 2AUXA 1W4TA 1CQDA 2DC9A 1ZIVA 5CVOB 4P6GA 3U8EA 1U9QX 4W5CA 4YYQA 2DJGB 1IWDA 1CVZA 1PADA 3MORA 3H7DA 4X6IA 4AXLA 1ITOA 1POPA 3TNXA 3IUTA 1BP4A 3HHAA 3F75A 1MS6A 2E01A 4MSXA 4CDFB 2DCCA 2AS8A 1NB5A 3KX1A 4BGFA 4B55A 4QBBA 2IPPB 2OULA 2G8EA 4GUZA 2XU4A 2F1GA 4FJCA 4W5BA 2FO5A 4NV8A 3CH2X 2NQDB 3H6SA 1JQPA 2B1NA 3V6EA 2ARYA 4QRXA 2VFBA 4YVAA 2FYEA 1S4VA 4XR7A 2BDZA 3QT4A 1E2TA 3O0UA 1X9YA 3OVZA 1YT7A 1AU0A 2E02A 3K8UA 4CDCB 2HXZA 1ME3A 2DZYA 4YYUA 2B1MA 2DCAA 1AYWA 4YYWA 1NQCA 1U9XA 2C0YA 1Y08A 4YYVA 4XUIA 2HH5A 7PCKA 1AYUA 4Q8HA 3N4CA 1CV8A 1U9VA 2FRQA 2DJFB 1GX3A 1KFXL 3H8BA 5CHTA 3M99A 1YALA 3IEJA 5CVMA 4BQVA 2NQAA 1DEUA 4AXMA 5CVNB 3DF0A 2DCDA 3QSDA 4N8WA 8PCHA 2E00A 2NQIA 1CJLA 2BSZA 2AYOA 3WXEA 3HHIA 3F5VA 5FPWA 3USVA 1M6DA 3CH3X 4YYSA 1PPPA 3MHHA 5F02A 3O1GA 1SP4B 4MZSA 4BS6A 1MDWA 1QMYA 2AUZA 2G7YA 1PCIA 2PADA 2IBIA 1TLOA 1ICFA 4QH6A 2JQFR 3I06A 3PW3A 1AU3A 4WA6A 2YJBA 3LXSA 4N79A 4YV8A 1U9WA 3CBJA 1NB3A 2E03A 3P5XA 2JQGR 3N3GA 1NPZA 4CDDB 4BSQA 1KFUL 2G8JA 1AIMA 3RVXA 5K16A 1KHQA 1EWLA 2VFCA 2P0RA 1AU2A 1EF7A 1F29A 1MEMA 3WXFA 1W5RA 4FIPA 3BC3A 3IMAA 3H89A 3KWBX 1TL9A 1PPOA 2FT2A 1QOLA 2DC6A 3P5UA 9PAPA 2P86A 4PP2E 3RVWA 3KFQA 2AIMA 3OF8A 3LTWA 2XU3A 2YJCA 3B79A 1FH0A 1CS8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1MEG A;  4DMX A;  2FRA A;  4G54 A;  1YK8 A;  2VHS A;  2H7J A;  2FTD A;  4PP1 A;  2F7D A;  3MTN A;  2YJ2 A;  3KWZ A;  3BOW A;  5JH3 A;  2R9N A;  2ACT A;  1EWP A;  3I3T A;  2FUD A;  2R9C A;  3PBH A;  1GMY A;  3P5V A;  4PI3 A;  2ATO A;  2G6D A;  2R6N A;  4HWY A;  1F2C A;  5JA7 A;  4ZUX U;  2BDL A;  3HWN A;  4X6J A;  2GHU A;  3S3Q A;  1TU6 A;  4BPV A;  3CBK A;  2P7U A;  2O6X A;  4I04 A;  3BCN A;  4FK5 A;  3D6S A;  2PBH A;  3PNR A;  4DMY A;  1U5I A;  1VSN A;  5EF4 A;  3KKU A;  1PBH A;  1EWO A;  1PE6 A;  3WXG A;  2R9M A;  2PNS A;  1QXP A;  5J94 A;  4Q8G A;  4QRV A;  5PAD A;  1PIP A;  1CPJ A;  3LFY A;  2DC8 A;  4BS5 A;  2AU1 A;  2OP3 A;  3S3R A;  3OIS A;  1QDQ A;  1NLJ A;  3RVV A;  3BPM A;  1GLO A;  5CHV A;  4X6H A;  2HD5 A;  3BPF A;  3NHE A;  5A24 A;  1BQI A;  1XKG A;  1Q6K A;  1Y4H A;  1CB5 A;  4I05 A;  2HHN A;  2NQG A;  1BGO A;  3BWK A;  2CIO A;  3QJ3 A;  3ERV A;  1GEC E;  1VJV A;  3H8C A;  3KW9 A;  1O0E A;  2Y6E A;  3C9E A;  3V6C A;  1EWM A;  4I07 A;  1PPD A;  2FQ9 A;  6PAD A;  3OVX A;  3IOQ A;  1THE A;  1PPN A;  1A6R A;  4QRG A;  2CB5 A;  2DC7 A;  4N4Z A;  4OEL A;  1KHP A;  3IV2 A;  1CTE A;  2OZ2 A;  1K3B B;  1PXV A;  2YJ9 A;  3ZUA A;  4OEM A;  4RY2 A;  3K9M A;  3AI8 A;  1ME4 A;  3HD3 A;  3P5W A;  4KLB A;  1NL6 A;  4YYR A;  4K7C A;  3GCB A;  1STF E;  3MHS A;  1YK7 A;  1AU4 A;  4P6E A;  2DZZ A;  1HUC B;  2AVW A;  1DF0 A;  1MHW A;  3OF9 A;  3PDF A;  1GCB A;  2AYN A;  1ZCM A;  4CDE B;  1KXR A;  5EGW A;  2R9F A;  1F2A A;  1SNK A;  3N3K A;  3E1Z B;  1MIR A;  2XU5 A;  2PRE A;  2DCB A;  2Y5B A;  4W4U A;  1AEC A;  1YVB A;  3KSE A;  1BY8 A;  4MZO A;  2R9O A;  2WBF X;  4PAD A;  2YJ8 A;  1CSB B;  2VHF A;  2XU1 A;  1F2B A;  1ATK A;  2GFO A;  3K24 A;  1AYV A;  3IHP A;  4CZW A;  2AUX A;  1CQD A;  2DC9 A;  1ZIV A;  5CVO B;  4P6G A;  3U8E A;  1U9Q X;  4W5C A;  4YYQ A;  2DJG B;  1IWD A;  1CVZ A;  1PAD A;  3MOR A;  3H7D A;  4X6I A;  4AXL A;  1ITO A;  1POP A;  3TNX A;  3IUT A;  1BP4 A;  3HHA A;  3F75 A;  1MS6 A;  2E01 A;  4MSX A;  4CDF B;  2DCC A;  2AS8 A;  1NB5 A;  3KX1 A;  4QBB A;  2IPP B;  2OUL A;  2G8E A;  2XU4 A;  2F1G A;  4FJC A;  4W5B A;  2FO5 A;  3CH2 X;  2NQD B;  3H6S A;  1JQP A;  2B1N A;  3V6E A;  2ARY A;  4QRX A;  4YVA A;  2FYE A;  1S4V A;  4XR7 A;  2BDZ A;  3QT4 A;  3O0U A;  1X9Y A;  3OVZ A;  1YT7 A;  1AU0 A;  2E02 A;  3K8U A;  4CDC B;  2HXZ A;  1ME3 A;  2DZY A;  4YYU A;  2B1M A;  2DCA A;  1AYW A;  4YYW A;  1NQC A;  1U9X A;  2C0Y A;  1Y08 A;  4YYV A;  4XUI A;  2HH5 A;  7PCK A;  1AYU A;  4Q8H A;  3N4C A;  1CV8 A;  1U9V A;  2FRQ A;  2DJF B;  1KFX L;  3H8B A;  5CHT A;  3M99 A;  1YAL A;  3IEJ A;  5CVM A;  4BQV A;  2NQA A;  1DEU A;  4AXM A;  5CVN B;  3DF0 A;  2DCD A;  3QSD A;  4N8W A;  8PCH A;  2E00 A;  2NQI A;  1CJL A;  2AYO A;  3WXE A;  3HHI A;  3F5V A;  5FPW A;  3USV A;  1M6D A;  3CH3 X;  4YYS A;  1PPP A;  3MHH A;  5F02 A;  3O1G A;  1SP4 B;  4MZS A;  4BS6 A;  1MDW A;  1QMY A;  2AUZ A;  2G7Y A;  1PCI A;  2PAD A;  2IBI A;  1TLO A;  1ICF A;  4QH6 A;  2JQF R;  3I06 A;  3PW3 A;  1AU3 A;  4WA6 A;  2YJB A;  3LXS A;  4N79 A;  4YV8 A;  1U9W A;  3CBJ A;  1NB3 A;  2E03 A;  3P5X A;  2JQG R;  3N3G A;  1NPZ A;  4CDD B;  4BSQ A;  1KFU L;  2G8J A;  1AIM A;  3RVX A;  5K16 A;  1KHQ A;  1EWL A;  2P0R A;  1AU2 A;  1EF7 A;  1F29 A;  1MEM A;  3WXF A;  4FIP A;  3BC3 A;  3IMA A;  3H89 A;  3KWB X;  1TL9 A;  1PPO A;  2FT2 A;  1QOL A;  2DC6 A;  3P5U A;  9PAP A;  2P86 A;  4PP2 E;  3RVW A;  3KFQ A;  2AIM A;  3OF8 A;  2XU3 A;  2YJC A;  3B79 A;  1FH0 A;  1CS8 A; 
#chains in the Genus database with same CATH topology
 1MEG A;  4DMX A;  2FRA A;  4G54 A;  3PHW A;  1YK8 A;  2VHS A;  2H7J A;  2FTD A;  4MI7 A;  4PP1 A;  4REZ A;  2F7D A;  3MTN A;  2YJ2 A;  3KWZ A;  3BOW A;  5JH3 A;  2R9N A;  2ACT A;  1EWP A;  3I3T A;  2FUD A;  2R9C A;  3PBH A;  1GMY A;  4OVZ B;  3P5V A;  4PI3 A;  2ATO A;  2G6D A;  2R6N A;  4HWY A;  1F2C A;  5JA7 A;  4ZUX U;  2BDL A;  4IP3 A;  2JRI A;  3HWN A;  4X6J A;  2GHU A;  3S3Q A;  1TU6 A;  4BPV A;  3CBK A;  2P7U A;  2O6X A;  5EZQ A;  4I04 A;  3BCN A;  4FK5 A;  3W31 A;  3D6S A;  2BU3 A;  2PBH A;  3PNR A;  4DMY A;  1U5I A;  1VSN A;  5EF4 A;  3KKU A;  1PBH A;  1EWO A;  1PE6 A;  3WXG A;  3RNV A;  2R9M A;  2PNS A;  1QXP A;  5J94 A;  4Q8G A;  4QRV A;  5PAD A;  4BOP A;  1PIP A;  3BB7 A;  1CPJ A;  3LFY A;  2DC8 A;  4BS5 A;  2AU1 A;  2OP3 A;  3S3R A;  3OIS A;  1QDQ A;  5E6J A;  1NLJ A;  3RVV A;  3BPM A;  1GLO A;  5CHV A;  4X6H A;  2HD5 A;  4IUM A;  3BPF A;  4BOS A;  3NHE A;  5A24 A;  1BQI A;  4M0W A;  1XKG A;  1Q6K A;  1Y4H A;  1CB5 A;  4I05 A;  2HHN A;  2NQG A;  1BGO A;  2UZJ A;  5EZS A;  1UKF A;  3BWK A;  2CIO A;  3QJ3 A;  3ERV A;  3TRK A;  3C0R A;  1GEC E;  1VJV A;  2J7Q A;  3H8C A;  3KW9 A;  1O0E A;  2Y6E A;  3PHU A;  3C9E A;  2DOS A;  3V6C A;  1EWM A;  4I07 A;  1PPD A;  2FQ9 A;  6PAD A;  3OVX A;  3IOQ A;  1THE A;  1PPN A;  1A6R A;  4QRG A;  2CB5 A;  2DC7 A;  4N4Z A;  4OEL A;  4PT5 A;  1KHP A;  3B21 A;  1PVJ A;  3IV2 A;  1CTE A;  2OZ2 A;  1K3B B;  1PXV A;  2YJ9 A;  3ZUA A;  4OEM A;  4RY2 A;  3E9S A;  3K9M A;  3AI8 A;  4BOZ A;  1ME4 A;  3W30 A;  3HD3 A;  3P5W A;  4KLB A;  1NL6 A;  4YYR A;  4BOU A;  4K7C A;  3GCB A;  1STF E;  3MHS A;  1YK7 A;  1AU4 A;  4RF0 A;  4P6E A;  4WUR A;  2DZZ A;  1HUC B;  2AVW A;  1DF0 A;  3MTV A;  1MHW A;  2BTW A;  3OF9 A;  3PDF A;  4GUA A;  1GCB A;  2AYN A;  1ZCM A;  4CDE B;  1KXR A;  5EGW A;  2R9F A;  1F2A A;  1SNK A;  3N3K A;  3E1Z B;  1MIR A;  2XU5 A;  5KO3 A;  2PRE A;  2DCB A;  1YZB A;  2Y5B A;  4W4U A;  1AEC A;  1YVB A;  3KSE A;  1BY8 A;  4P16 A;  4MZO A;  2R9O A;  2WBF X;  4PAD A;  3TMP A;  2YJ8 A;  1CSB B;  2VHF A;  2XU1 A;  1F2B A;  1ATK A;  2GFO A;  5JZE A;  3K24 A;  4RNA A;  1AYV A;  3IHP A;  4CZW A;  2AUX A;  2Z84 A;  1CQD A;  2DC9 A;  1ZIV A;  5CVO B;  4P6G A;  3U8E A;  1U9Q X;  4W5C A;  4YYQ A;  3MJ5 A;  2DJG B;  1IWD A;  1CVZ A;  1PAD A;  4A5U A;  2BTW B;  3MOR A;  3H7D A;  4X6I A;  4AXL A;  1ITO A;  1POP A;  3TNX A;  3IUT A;  1BP4 A;  3HHA A;  3F75 A;  1MS6 A;  2E01 A;  4MSX A;  4CDF B;  2DCC A;  2AS8 A;  4OW0 A;  1NB5 A;  4OVZ A;  3KX1 A;  4QBB A;  2IPP B;  2OUL A;  2G8E A;  3ZNH A;  2XU4 A;  2F1G A;  4FJC A;  4W5B A;  2FO5 A;  3CH2 X;  2NQD B;  3H6S A;  1JQP A;  2B1N A;  3V6E A;  3O65 A;  2ARY A;  4QRX A;  4YVA A;  2FYE A;  1S4V A;  4XR7 A;  2J7Q C;  4RKX A;  2HWK A;  2BDZ A;  3QT4 A;  3O0U A;  1X9Y A;  3OVZ A;  1YT7 A;  1AU0 A;  2E02 A;  3K8U A;  4CDC B;  2HXZ A;  1ME3 A;  2DZY A;  4HXD B;  4YYU A;  3MP2 A;  2B1M A;  2DCA A;  1AYW A;  4YYW A;  1NQC A;  1U9X A;  2C0Y A;  1Y08 A;  4YYV A;  4XUI A;  2HH5 A;  7PCK A;  1AYU A;  1DKI A;  4XZX A;  4Q8H A;  3N4C A;  1CV8 A;  1U9V A;  2FRQ A;  4D8E A;  2DJF B;  1KFX L;  2FE8 A;  3IFU A;  3H8B A;  5CHT A;  3M99 A;  3PRP A;  1YAL A;  3IEJ A;  5CVM A;  4BQV A;  2NQA A;  1DEU A;  4MM3 B;  4AXM A;  5CVN B;  4BOQ A;  3DF0 A;  2DCD A;  3QSD A;  4N8W A;  8PCH A;  2E00 A;  2NQI A;  1CJL A;  2AYO A;  3BY4 A;  3WXE A;  3HHI A;  3F5V A;  3PSE A;  5FPW A;  3USV A;  4D8I A;  1M6D A;  3CH3 X;  4YYS A;  1PPP A;  3MHH A;  5F02 A;  3O1G A;  1SP4 B;  4MZS A;  3PHX A;  1MDW A;  1QMY A;  2AUZ A;  4BS6 A;  2G7Y A;  1PCI A;  2PAD A;  2IBI A;  1TLO A;  1ICF A;  4QH6 A;  2JQF R;  3I06 A;  4RF1 A;  3PRM A;  3PW3 A;  1AU3 A;  4WA6 A;  2YJB A;  2JTC A;  3LXS A;  4N79 A;  4YV8 A;  1U9W A;  3CBJ A;  2AGA A;  1NB3 A;  2E03 A;  3BBA A;  3P5X A;  2JQG R;  3N3G A;  1NPZ A;  4CDD B;  4BSQ A;  1KFU L;  2G8J A;  1AIM A;  3RVX A;  5K16 A;  1KHQ A;  1EWL A;  2P0R A;  1AU2 A;  1EF7 A;  1F29 A;  1MEM A;  3WXF A;  4FIP A;  3BC3 A;  3IMA A;  3PT2 A;  3H89 A;  3KWB X;  3OQC A;  1TL9 A;  1PPO A;  2FT2 A;  1QOL A;  2DC6 A;  4ZTB A;  3P5U A;  9PAP A;  2P86 A;  4PP2 E;  3RVW A;  3KFQ A;  2AIM A;  4D8B A;  3OF8 A;  2XU3 A;  2YJC A;  3B79 A;  1FH0 A;  1CS8 A;  4R3D A; 
#chains in the Genus database with same CATH homology
 1MEG A;  4DMX A;  2FRA A;  4G54 A;  1YK8 A;  2VHS A;  2H7J A;  2FTD A;  4NV7 A;  4PP1 A;  2F7D A;  3MTN A;  2YJ2 A;  3KWZ A;  3BOW A;  5JH3 A;  2R9N A;  2ACT A;  1EWP A;  3I3T A;  2FUD A;  2R9C A;  3PBH A;  1GMY A;  3P5V A;  4PI3 A;  2ATO A;  2G6D A;  2R6N A;  4HWY A;  1F2C A;  5JA7 A;  4ZUX U;  2BDL A;  3HWN A;  4X6J A;  2GHU A;  3S3Q A;  1TU6 A;  4BPV A;  3CBK A;  2P7U A;  3D9W A;  2O6X A;  4I04 A;  3BCN A;  4FK5 A;  3D6S A;  2PBH A;  3PNR A;  4DMY A;  1U5I A;  1VSN A;  5EF4 A;  3KKU A;  1PBH A;  1EWO A;  1PE6 A;  3WXG A;  2R9M A;  2PNS A;  1QXP A;  5J94 A;  4Q8G A;  4QRV A;  5PAD A;  1PIP A;  1CPJ A;  3LFY A;  2DC8 A;  4BS5 A;  2AU1 A;  2OP3 A;  3S3R A;  3OIS A;  1QDQ A;  1NLJ A;  3RVV A;  3BPM A;  1GLO A;  5CHV A;  4X6H A;  2HD5 A;  3BPF A;  3NHE A;  5A24 A;  1BQI A;  1XKG A;  1Q6K A;  1Y4H A;  1CB5 A;  4I05 A;  2HHN A;  2NQG A;  1BGO A;  3BWK A;  2CIO A;  3QJ3 A;  3ERV A;  1GEC E;  1VJV A;  3H8C A;  3KW9 A;  1O0E A;  2Y6E A;  3C9E A;  3V6C A;  1EWM A;  4I07 A;  1PPD A;  2FQ9 A;  6PAD A;  3OVX A;  3IOQ A;  1THE A;  1PPN A;  1A6R A;  4QRG A;  2CB5 A;  2DC7 A;  4N4Z A;  4OEL A;  1KHP A;  3IV2 A;  1CTE A;  2OZ2 A;  1K3B B;  1PXV A;  2YJ9 A;  3ZUA A;  4OEM A;  4C5P A;  4RY2 A;  3K9M A;  3AI8 A;  1ME4 A;  3HD3 A;  3P5W A;  4KLB A;  1NL6 A;  4YYR A;  4K7C A;  1W6F A;  3GCB A;  1STF E;  3MHS A;  1YK7 A;  1AU4 A;  4P6E A;  2DZZ A;  1HUC B;  2AVW A;  1DF0 A;  1MHW A;  3OF9 A;  3PDF A;  1GCB A;  2AYN A;  1ZCM A;  4CDE B;  1KXR A;  5EGW A;  2R9F A;  1F2A A;  1SNK A;  3N3K A;  3E1Z B;  1MIR A;  2XU5 A;  2PRE A;  2DCB A;  2Y5B A;  4W4U A;  1AEC A;  1YVB A;  3KSE A;  1BY8 A;  4MZO A;  2R9O A;  2WBF X;  4PAD A;  2YJ8 A;  1CSB B;  2VHF A;  2XU1 A;  1F2B A;  1ATK A;  2GFO A;  3K24 A;  1AYV A;  3IHP A;  4CZW A;  2AUX A;  1W4T A;  1CQD A;  2DC9 A;  1ZIV A;  5CVO B;  4P6G A;  3U8E A;  1U9Q X;  4W5C A;  4YYQ A;  2DJG B;  1IWD A;  1CVZ A;  1PAD A;  3MOR A;  3H7D A;  4X6I A;  4AXL A;  1ITO A;  1POP A;  3TNX A;  3IUT A;  1BP4 A;  3HHA A;  3F75 A;  1MS6 A;  2E01 A;  4MSX A;  4CDF B;  2DCC A;  2AS8 A;  1NB5 A;  3KX1 A;  4BGF A;  4B55 A;  4QBB A;  2IPP B;  2OUL A;  2G8E A;  4GUZ A;  2XU4 A;  2F1G A;  4FJC A;  4W5B A;  2FO5 A;  4NV8 A;  3CH2 X;  2NQD B;  3H6S A;  1JQP A;  2B1N A;  3V6E A;  2ARY A;  4QRX A;  2VFB A;  4YVA A;  2FYE A;  1S4V A;  4XR7 A;  2BDZ A;  3QT4 A;  1E2T A;  3O0U A;  1X9Y A;  3OVZ A;  1YT7 A;  1AU0 A;  2E02 A;  3K8U A;  4CDC B;  2HXZ A;  1ME3 A;  2DZY A;  4YYU A;  2B1M A;  2DCA A;  1AYW A;  4YYW A;  1NQC A;  1U9X A;  2C0Y A;  1Y08 A;  4YYV A;  4XUI A;  2HH5 A;  7PCK A;  1AYU A;  4Q8H A;  3N4C A;  1CV8 A;  1U9V A;  2FRQ A;  2DJF B;  1GX3 A;  1KFX L;  3H8B A;  5CHT A;  3M99 A;  1YAL A;  3IEJ A;  5CVM A;  4BQV A;  2NQA A;  1DEU A;  4AXM A;  5CVN B;  3DF0 A;  2DCD A;  3QSD A;  4N8W A;  8PCH A;  2E00 A;  2NQI A;  1CJL A;  2BSZ A;  2AYO A;  3WXE A;  3HHI A;  3F5V A;  5FPW A;  3USV A;  1M6D A;  3CH3 X;  4YYS A;  1PPP A;  3MHH A;  5F02 A;  3O1G A;  1SP4 B;  4MZS A;  4BS6 A;  1MDW A;  1QMY A;  2AUZ A;  2G7Y A;  1PCI A;  2PAD A;  2IBI A;  1TLO A;  1ICF A;  4QH6 A;  2JQF R;  3I06 A;  3PW3 A;  1AU3 A;  4WA6 A;  2YJB A;  3LXS A;  4N79 A;  4YV8 A;  1U9W A;  3CBJ A;  1NB3 A;  2E03 A;  3P5X A;  2JQG R;  3N3G A;  1NPZ A;  4CDD B;  4BSQ A;  1KFU L;  2G8J A;  1AIM A;  3RVX A;  5K16 A;  1KHQ A;  1EWL A;  2VFC A;  2P0R A;  1AU2 A;  1EF7 A;  1F29 A;  1MEM A;  3WXF A;  1W5R A;  4FIP A;  3BC3 A;  3IMA A;  3H89 A;  3KWB X;  1TL9 A;  1PPO A;  2FT2 A;  1QOL A;  2DC6 A;  3P5U A;  9PAP A;  2P86 A;  4PP2 E;  3RVW A;  3KFQ A;  2AIM A;  3OF8 A;  3LTW A;  2XU3 A;  2YJC A;  3B79 A;  1FH0 A;  1CS8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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