1PIPA

Crystal structure of papain-succinyl-gln-val-val-ala-ala-p-nitroanilide complex at 1.7 angstroms resolution: noncovalent binding mode of a common sequence of endogenous thiol protease inhibitors
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
212
structure length
212
Chain Sequence
IPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNQYSEQELLDCDRRSYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKTDGVRQVQPYNQGALLYSIANQPVSVVLQAAGKDFQLYRGGIFVGPCGNKVDHAVAAVGYGPNYILIKNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPVKN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of papain-succinyl-Gln-Val-Val-Ala-Ala-p-nitroanilide complex at 1.7-A resolution: noncovalent binding mode of a common sequence of endogenous thiol protease inhibitors.
pubmed doi rcsb
molecule keywords PAPAIN
molecule tags Hydrolase/hydrolase inhibitor
source organism Carica papaya
total genus 66
structure length 212
sequence length 212
ec nomenclature ec 3.4.22.2: Papain.
pdb deposition date 1992-10-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1pipA00
7PCKA 2DCCA 5JH3A 3I3TA 2Y6EA 4G54A 2CB5A 1HUCB 2CIOA 5FPWA 1ITOA 3F5VA 4PP1A 1BQIA 1AYVA 1PE6A 3MORA 1MHWA 2PBHA 2ARYA 2FQ9A 1PPNA 4MSXA 1VSNA 5PADA 3ERVA 4YYUA 2NQGA 2OP3A 1NB3A 2YJ8A 1IWDA 4CDDB 4QRXA 3HWNA 2C0YA 4I07A 1EF7A 3CH3X 4N4ZA 2ACTA 2VHSA 2VHFA 3H8CA 3GCBA 3P5VA 3F75A 4AXLA 2DC6A 3H6SA 2FRQA 3HHAA 1DF0A 1AYWA 1CV8A 4WA6A 3C9EA 2FRAA 1ME4A 1PPOA 2AVWA 2BDLA 1BGOA 2AIMA 4P6EA 2GFOA 2PADA 3MHSA 3BPFA 1GMYA 2DCAA 2AYOA 2XU5A 2R9CA 1CVZA 4PADA 3IHPA 2P0RA 1DEUA 2FUDA 2DJGB 2AYNA 5CVOB 1AIMA 1BY8A 2AUXA 3B79A 2Y5BA 4CDCB 3LXSA 2JQFR 2R9FA 1QXPA 3KW9A 3IOQA 1VJVA 6PADA 3N3GA 1MEMA 4BS5A 1X9YA 1ICFA 2YJBA 4XR7A 5J94A 4N79A 4YVAA 3P5WA 1ZIVA 8PCHA 1KFUL 1U5IA 1Y4HA 2H7JA 4X6HA 2HHNA 4W5CA 2IBIA 1Y08A 2E01A 3RVXA 4PP2E 4BQVA 4QRVA 9PAPA 3PW3A 4X6JA 1AECA 1U9VA 1TU6A 2YJCA 3N4CA 3CBJA 2FO5A 3LFYA 1YK7A 2OZ2A 2DJFB 1QDQA 3USVA 2NQAA 4FK5A 1GCBA 1F2AA 2JQGR 5EGWA 4BPVA 4AXMA 4FJCA 3K9MA 3IEJA 2P86A 3PNRA 1CB5A 3DF0A 3K24A 1GECE 4FIPA 3WXEA 3H7DA 4BSQA 2G8JA 3CH2X 3TNXA 3RVVA 3BCNA 1Q6KA 1GLOA 2G7YA 2AUZA 3S3QA 2WBFX 1EWLA 2F1GA 1TLOA 4BS6A 2P7UA 2AS8A 2XU1A 1KXRA 5CHVA 2YJ2A 1KHQA 2DZYA 2R6NA 1YT7A 1POPA 1CTEA 4YYRA 5CHTA 3QT4A 2R9NA 3E1ZB 3PBHA 4RY2A 4PI3A 3OF8A 5JA7A 3OISA 3KWZA 1F29A 2FT2A 3ZUAA 4DMXA 2NQIA 1KFXL 5A24A 1YALA 1MS6A 4P6GA 1JQPA 3QSDA 2G8EA 4DMYA 3I06A 2IPPB 3PDFA 1PADA 4YYWA 2YJ9A 5CVMA 5K16A 4YYVA 1PIPA 3KX1A 2G6DA 4CDFB 1QOLA 4HWYA 3V6EA 1S4VA 4KLBA 1PBHA 3MHHA 4YYSA 2FTDA 2DCDA 1PCIA 1CPJA 1THEA 3CBKA 1STFE 4MZOA 1AU2A 1ATKA 1AYUA 4YYQA 3RVWA 3HHIA 1O0EA 4Q8HA 2HH5A 2DC7A 2B1MA 4ZUXU 2O6XA 5CVNB 4CDEB 4XUIA 2DC9A 1CSBB 1U9QX 4OEMA 1F2BA 1U9XA 1EWMA 1NPZA 2R9MA 1CJLA 2XU3A 3H89A 3NHEA 3O1GA 3KSEA 3K8UA 3BWKA 1FH0A 1CQDA 1CS8A 3AI8A 1XKGA 3P5XA 3BOWA 2NQDB 2OULA 1KHPA 3V6CA 1MDWA 4QRGA 4W4UA 1ME3A 1EWPA 1MEGA 2HD5A 2DC8A 3IUTA 3BPMA 3OVXA 2BDZA 1EWOA 3OVZA 1NL6A 1PPPA 4W5BA 3U8EA 4QH6A 1SP4B 3IV2A 2HXZA 3BC3A 3KFQA 4MZSA 4QBBA 4X6IA 1YVBA 1PXVA 4CZWA 2GHUA 3KKUA 1PPDA 3M99A 2E02A 1TL9A 1A6RA 3S3RA 2DZZA 4K7CA 4I05A 3N3KA 2XU4A 4N8WA 2E00A 1AU4A 3IMAA 1U9WA 1AU0A 3QJ3A 4OELA 1YK8A 2PNSA 2PREA 3MTNA 3WXFA 3WXGA 2ATOA 1SNKA 3OF9A 3D6SA 2E03A 2AU1A 3HD3A 1K3BB 2FYEA 1F2CA 1QMYA 4I04A 1AU3A 2DCBA 2B1NA 1BP4A 1NLJA 5F02A 3KWBX 2R9OA 1NQCA 3H8BA 1MIRA 4Q8GA 2F7DA 1NB5A 3P5UA 1M6DA 1ZCMA 4YV8A 5EF4A 3O0UA
chains in the Genus database with same CATH superfamily
7PCKA 2DCCA 5JH3A 3I3TA 2Y6EA 3B21A 4G54A 2CB5A 1HUCB 2CIOA 5FPWA 1ITOA 3F5VA 4PP1A 1BQIA 1AYVA 5EZQA 1PE6A 2BTWA 3MORA 1MHWA 2PBHA 2ARYA 2FQ9A 1PPNA 4MSXA 4D8BA 1VSNA 5PADA 1PVJA 3ERVA 4YYUA 2NQGA 2OP3A 1NB3A 3O65A 2YJ8A 1IWDA 4CDDB 4QRXA 4ZTBA 3HWNA 2C0YA 4I07A 2Z84A 1EF7A 3CH3X 4N4ZA 2ACTA 2VHSA 2VHFA 3H8CA 3GCBA 3P5VA 4BOPA 3F75A 4AXLA 2DC6A 3H6SA 3BBAA 2FRQA 3HHAA 1DF0A 5JZEA 1AYWA 1CV8A 4WA6A 2UZJA 3C9EA 2FRAA 1ME4A 1PPOA 2J7QC 2AVWA 4RNAA 2BDLA 1YZBA 1BGOA 3C0RA 2AIMA 4P6EA 4D8EA 2GFOA 4GUAA 2PADA 3MHSA 3BPFA 1GMYA 2DCAA 2AYOA 2XU5A 2R9CA 1CVZA 4PADA 3IHPA 2P0RA 1DEUA 2FUDA 2DJGB 2AYNA 5CVOB 1AIMA 2JRIA 4BOUA 1BY8A 2AUXA 4RF1A 3B79A 2Y5BA 4CDCB 3LXSA 2JQFR 2R9FA 1QXPA 3KW9A 3IOQA 1VJVA 3PRMA 6PADA 3N3GA 1MEMA 4BS5A 1X9YA 1ICFA 2YJBA 4XR7A 5J94A 4N79A 3TMPA 4YVAA 3P5WA 1ZIVA 8PCHA 1KFUL 1U5IA 1Y4HA 2H7JA 4X6HA 3E9SA 2HHNA 4W5CA 2IBIA 1Y08A 2E01A 3RVXA 4PP2E 4BQVA 4QRVA 9PAPA 3PW3A 4X6JA 1AECA 1U9VA 1TU6A 2YJCA 3N4CA 3CBJA 2FO5A 3LFYA 1YK7A 2OZ2A 4A5UA 2DJFB 1QDQA 3USVA 2NQAA 4OVZB 4FK5A 1GCBA 1F2AA 2JQGR 5EGWA 2JTCA 4BPVA 1DKIA 4AXMA 4FJCA 3K9MA 3IEJA 2P86A 3PNRA 4WURA 1CB5A 3DF0A 3K24A 5E6JA 1GECE 2BTWB 4FIPA 3TRKA 3WXEA 3H7DA 4BSQA 2G8JA 3CH2X 3TNXA 3RVVA 3BCNA 1Q6KA 4BOSA 1GLOA 2G7YA 2AUZA 3S3QA 4MM3B 2WBFX 3BB7A 4MI7A 1EWLA 2F1GA 1TLOA 4BS6A 3PHWA 2P7UA 2AS8A 2XU1A 1KXRA 5CHVA 2YJ2A 1KHQA 2DZYA 2FE8A 2R6NA 1YT7A 1POPA 1CTEA 2J7QA 4YYRA 5CHTA 3QT4A 2R9NA 3E1ZB 3PBHA 4RY2A 4PI3A 3OF8A 5JA7A 2DOSA 3OISA 3KWZA 1F29A 4PT5A 2FT2A 3ZUAA 4DMXA 2NQIA 4IP3A 3W30A 1KFXL 5A24A 1YALA 1MS6A 4P6GA 1JQPA 3QSDA 4RKXA 2G8EA 4DMYA 3I06A 2IPPB 3PDFA 1PADA 4YYWA 2YJ9A 5CVMA 5K16A 5KO3A 4YYVA 3RNVA 1PIPA 3KX1A 2G6DA 4CDFB 1QOLA 4HWYA 3V6EA 1S4VA 4KLBA 1PBHA 3MHHA 4YYSA 2FTDA 2DCDA 1PCIA 1CPJA 1THEA 4D8IA 3CBKA 1STFE 4OVZA 4MZOA 1AU2A 3MP2A 3OQCA 1ATKA 1AYUA 4YYQA 3RVWA 3HHIA 1O0EA 4Q8HA 5EZSA 2HH5A 2DC7A 3PHUA 2B1MA 4ZUXU 2O6XA 5CVNB 4M0WA 4CDEB 4XUIA 2DC9A 3IFUA 1CSBB 1U9QX 4BOQA 4OEMA 1F2BA 4OW0A 1U9XA 1EWMA 1NPZA 2R9MA 1CJLA 3W31A 2XU3A 3H89A 3NHEA 3O1GA 3KSEA 3K8UA 3BWKA 1FH0A 1CQDA 1CS8A 3AI8A 1XKGA 3P5XA 3BOWA 2NQDB 2OULA 1KHPA 3MTVA 3V6CA 4XZXA 3ZNHA 1MDWA 4QRGA 4W4UA 1ME3A 1EWPA 1MEGA 2HD5A 2DC8A 4REZA 3IUTA 2HWKA 3BPMA 3OVXA 2BDZA 1EWOA 3OVZA 1NL6A 1PPPA 4P16A 4HXDB 4W5BA 3U8EA 4QH6A 1SP4B 3IV2A 2HXZA 3BC3A 3KFQA 4MZSA 4QBBA 4X6IA 1YVBA 3BY4A 1PXVA 3PRPA 4CZWA 2GHUA 3PT2A 3KKUA 1PPDA 3M99A 2E02A 1TL9A 1A6RA 4IUMA 3S3RA 4R3DA 2DZZA 4K7CA 4I05A 3N3KA 3PHXA 2XU4A 4N8WA 2E00A 1AU4A 4BOZA 3IMAA 1U9WA 1AU0A 3QJ3A 4OELA 1YK8A 2PNSA 2PREA 3MTNA 3WXFA 3WXGA 2ATOA 1SNKA 3OF9A 3D6SA 2E03A 2AU1A 2BU3A 1K3BB 3HD3A 3PSEA 2FYEA 1F2CA 1QMYA 4I04A 1AU3A 2DCBA 2B1NA 1BP4A 1NLJA 5F02A 3KWBX 2R9OA 1UKFA 1NQCA 3H8BA 1MIRA 4Q8GA 2AGAA 4RF0A 2F7DA 1NB5A 3P5UA 1M6DA 1ZCMA 4YV8A 5EF4A 3MJ5A 3O0UA
chains in the Genus database with same CATH topology
7PCKA 2DCCA 5JH3A 3I3TA 2Y6EA 4C5PA 4G54A 2CB5A 1HUCB 2CIOA 5FPWA 1ITOA 3F5VA 4PP1A 1BQIA 1AYVA 1PE6A 3MORA 1MHWA 2PBHA 2ARYA 2FQ9A 1PPNA 4MSXA 4GUZA 1VSNA 5PADA 3ERVA 4YYUA 2NQGA 2OP3A 1NB3A 2YJ8A 1IWDA 4CDDB 4QRXA 3HWNA 2C0YA 4I07A 1EF7A 3CH3X 4N4ZA 2ACTA 2VHSA 2VHFA 3H8CA 3GCBA 3P5VA 3F75A 4AXLA 2DC6A 3H6SA 2FRQA 3HHAA 1DF0A 1AYWA 1CV8A 4WA6A 3C9EA 2FRAA 1ME4A 1PPOA 2AVWA 2BDLA 1BGOA 2AIMA 4P6EA 2GFOA 2PADA 3MHSA 3BPFA 1GMYA 1W4TA 2DCAA 2AYOA 2XU5A 2R9CA 1CVZA 4PADA 3D9WA 3IHPA 2P0RA 1DEUA 2FUDA 2DJGB 2AYNA 5CVOB 1AIMA 1BY8A 2AUXA 3B79A 2Y5BA 4CDCB 3LXSA 2JQFR 2R9FA 1QXPA 3KW9A 3LTWA 3IOQA 1VJVA 6PADA 3N3GA 1MEMA 4BS5A 1X9YA 1ICFA 2YJBA 4XR7A 5J94A 4N79A 4YVAA 3P5WA 1ZIVA 8PCHA 1KFUL 1U5IA 1Y4HA 2H7JA 4X6HA 2HHNA 4W5CA 2IBIA 1Y08A 2E01A 3RVXA 1W5RA 4PP2E 4BQVA 4QRVA 9PAPA 3PW3A 4X6JA 1AECA 1U9VA 1TU6A 2YJCA 3N4CA 3CBJA 2FO5A 3LFYA 1YK7A 2OZ2A 2DJFB 1QDQA 3USVA 2NQAA 4FK5A 1GCBA 1F2AA 2JQGR 5EGWA 4BPVA 4AXMA 4FJCA 3K9MA 3IEJA 2P86A 3PNRA 1CB5A 3DF0A 3K24A 1GECE 4FIPA 3WXEA 3H7DA 4BSQA 2G8JA 3CH2X 3TNXA 3RVVA 3BCNA 1Q6KA 1GLOA 2G7YA 2AUZA 3S3QA 2WBFX 1EWLA 2F1GA 1TLOA 4BS6A 2P7UA 2AS8A 2XU1A 1KXRA 5CHVA 2YJ2A 1KHQA 2DZYA 2R6NA 1YT7A 1POPA 1CTEA 4YYRA 5CHTA 3QT4A 2R9NA 3E1ZB 3PBHA 4RY2A 4PI3A 3OF8A 5JA7A 3OISA 4NV7A 3KWZA 1F29A 2FT2A 3ZUAA 4DMXA 2NQIA 1KFXL 5A24A 1YALA 1MS6A 4P6GA 1JQPA 3QSDA 2G8EA 4DMYA 3I06A 2IPPB 3PDFA 1PADA 4YYWA 2YJ9A 5CVMA 5K16A 4YYVA 4BGFA 1PIPA 3KX1A 2G6DA 4CDFB 1QOLA 4HWYA 3V6EA 1S4VA 4KLBA 1PBHA 3MHHA 4YYSA 2FTDA 2DCDA 1PCIA 1CPJA 1THEA 3CBKA 1STFE 4MZOA 1AU2A 1ATKA 1AYUA 4YYQA 3RVWA 3HHIA 1W6FA 1O0EA 4Q8HA 2HH5A 2DC7A 2B1MA 4ZUXU 2O6XA 1GX3A 5CVNB 4CDEB 4XUIA 2DC9A 1CSBB 1U9QX 4OEMA 1F2BA 1U9XA 1EWMA 1NPZA 2R9MA 1CJLA 2XU3A 3H89A 3NHEA 3O1GA 3KSEA 3K8UA 3BWKA 1FH0A 1CQDA 1CS8A 3AI8A 1XKGA 3P5XA 3BOWA 2NQDB 2OULA 1KHPA 3V6CA 1MDWA 4QRGA 4W4UA 1ME3A 1EWPA 1MEGA 2HD5A 2DC8A 3IUTA 3BPMA 3OVXA 2BDZA 1E2TA 1EWOA 3OVZA 1NL6A 1PPPA 2VFCA 4W5BA 3U8EA 4QH6A 4B55A 1SP4B 3IV2A 2HXZA 3BC3A 3KFQA 4MZSA 4QBBA 4X6IA 1YVBA 1PXVA 4CZWA 2GHUA 3KKUA 1PPDA 3M99A 2E02A 1TL9A 1A6RA 3S3RA 2DZZA 4K7CA 4I05A 3N3KA 2XU4A 4N8WA 2E00A 1AU4A 3IMAA 1U9WA 1AU0A 3QJ3A 4OELA 1YK8A 2PNSA 2PREA 3MTNA 3WXFA 3WXGA 2ATOA 1SNKA 3OF9A 3D6SA 2E03A 2AU1A 3HD3A 1K3BB 2VFBA 2FYEA 1F2CA 1QMYA 4I04A 1AU3A 2DCBA 2BSZA 2B1NA 1BP4A 1NLJA 4NV8A 5F02A 3KWBX 2R9OA 1NQCA 3H8BA 1MIRA 4Q8GA 2F7DA 1NB5A 3P5UA 1M6DA 1ZCMA 4YV8A 5EF4A 3O0UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 7PCK A;  2DCC A;  5JH3 A;  3I3T A;  2Y6E A;  4G54 A;  2CB5 A;  1HUC B;  2CIO A;  5FPW A;  1ITO A;  3F5V A;  4PP1 A;  1BQI A;  1AYV A;  1PE6 A;  3MOR A;  1MHW A;  2PBH A;  2ARY A;  2FQ9 A;  1PPN A;  4MSX A;  1VSN A;  5PAD A;  3ERV A;  4YYU A;  2NQG A;  2OP3 A;  1NB3 A;  2YJ8 A;  1IWD A;  4CDD B;  4QRX A;  3HWN A;  2C0Y A;  4I07 A;  1EF7 A;  3CH3 X;  4N4Z A;  2ACT A;  2VHS A;  2VHF A;  3H8C A;  3GCB A;  3P5V A;  3F75 A;  4AXL A;  2DC6 A;  3H6S A;  2FRQ A;  3HHA A;  1DF0 A;  1AYW A;  1CV8 A;  4WA6 A;  3C9E A;  2FRA A;  1ME4 A;  1PPO A;  2AVW A;  2BDL A;  1BGO A;  2AIM A;  4P6E A;  2GFO A;  2PAD A;  3MHS A;  3BPF A;  1GMY A;  2DCA A;  2AYO A;  2XU5 A;  2R9C A;  1CVZ A;  4PAD A;  3IHP A;  2P0R A;  1DEU A;  2FUD A;  2DJG B;  2AYN A;  5CVO B;  1AIM A;  1BY8 A;  2AUX A;  3B79 A;  2Y5B A;  4CDC B;  3LXS A;  2JQF R;  2R9F A;  1QXP A;  3KW9 A;  3IOQ A;  1VJV A;  6PAD A;  3N3G A;  1MEM A;  4BS5 A;  1X9Y A;  1ICF A;  2YJB A;  4XR7 A;  5J94 A;  4N79 A;  4YVA A;  3P5W A;  1ZIV A;  8PCH A;  1KFU L;  1U5I A;  1Y4H A;  2H7J A;  4X6H A;  2HHN A;  4W5C A;  2IBI A;  1Y08 A;  2E01 A;  3RVX A;  4PP2 E;  4BQV A;  4QRV A;  9PAP A;  3PW3 A;  4X6J A;  1AEC A;  1U9V A;  1TU6 A;  2YJC A;  3N4C A;  3CBJ A;  2FO5 A;  3LFY A;  1YK7 A;  2OZ2 A;  2DJF B;  1QDQ A;  3USV A;  2NQA A;  4FK5 A;  1GCB A;  1F2A A;  2JQG R;  5EGW A;  4BPV A;  4AXM A;  4FJC A;  3K9M A;  3IEJ A;  2P86 A;  3PNR A;  1CB5 A;  3DF0 A;  3K24 A;  1GEC E;  4FIP A;  3WXE A;  3H7D A;  4BSQ A;  2G8J A;  3CH2 X;  3TNX A;  3RVV A;  3BCN A;  1Q6K A;  1GLO A;  2G7Y A;  2AUZ A;  3S3Q A;  2WBF X;  1EWL A;  2F1G A;  1TLO A;  4BS6 A;  2P7U A;  2AS8 A;  2XU1 A;  1KXR A;  5CHV A;  2YJ2 A;  1KHQ A;  2DZY A;  2R6N A;  1YT7 A;  1POP A;  1CTE A;  4YYR A;  5CHT A;  3QT4 A;  2R9N A;  3E1Z B;  3PBH A;  4RY2 A;  4PI3 A;  3OF8 A;  5JA7 A;  3OIS A;  3KWZ A;  1F29 A;  2FT2 A;  3ZUA A;  4DMX A;  2NQI A;  1KFX L;  5A24 A;  1YAL A;  1MS6 A;  4P6G A;  1JQP A;  3QSD A;  2G8E A;  4DMY A;  3I06 A;  2IPP B;  3PDF A;  1PAD A;  4YYW A;  2YJ9 A;  5CVM A;  5K16 A;  4YYV A;  1PIP A;  3KX1 A;  2G6D A;  4CDF B;  1QOL A;  4HWY A;  3V6E A;  1S4V A;  4KLB A;  1PBH A;  3MHH A;  4YYS A;  2FTD A;  2DCD A;  1PCI A;  1CPJ A;  1THE A;  3CBK A;  1STF E;  4MZO A;  1AU2 A;  1ATK A;  1AYU A;  4YYQ A;  3RVW A;  3HHI A;  1O0E A;  4Q8H A;  2HH5 A;  2DC7 A;  2B1M A;  4ZUX U;  2O6X A;  5CVN B;  4CDE B;  4XUI A;  2DC9 A;  1CSB B;  1U9Q X;  4OEM A;  1F2B A;  1U9X A;  1EWM A;  1NPZ A;  2R9M A;  1CJL A;  2XU3 A;  3H89 A;  3NHE A;  3O1G A;  3KSE A;  3K8U A;  3BWK A;  1FH0 A;  1CQD A;  1CS8 A;  3AI8 A;  1XKG A;  3P5X A;  3BOW A;  2NQD B;  2OUL A;  1KHP A;  3V6C A;  1MDW A;  4QRG A;  4W4U A;  1ME3 A;  1EWP A;  1MEG A;  2HD5 A;  2DC8 A;  3IUT A;  3BPM A;  3OVX A;  2BDZ A;  1EWO A;  3OVZ A;  1NL6 A;  1PPP A;  4W5B A;  3U8E A;  4QH6 A;  1SP4 B;  3IV2 A;  2HXZ A;  3BC3 A;  3KFQ A;  4MZS A;  4QBB A;  4X6I A;  1YVB A;  1PXV A;  4CZW A;  2GHU A;  3KKU A;  1PPD A;  3M99 A;  2E02 A;  1TL9 A;  1A6R A;  3S3R A;  2DZZ A;  4K7C A;  4I05 A;  3N3K A;  2XU4 A;  4N8W A;  2E00 A;  1AU4 A;  3IMA A;  1U9W A;  1AU0 A;  3QJ3 A;  4OEL A;  1YK8 A;  2PNS A;  2PRE A;  3MTN A;  3WXF A;  3WXG A;  2ATO A;  1SNK A;  3OF9 A;  3D6S A;  2E03 A;  2AU1 A;  3HD3 A;  1K3B B;  2FYE A;  1F2C A;  1QMY A;  4I04 A;  1AU3 A;  2DCB A;  2B1N A;  1BP4 A;  1NLJ A;  5F02 A;  3KWB X;  2R9O A;  1NQC A;  3H8B A;  1MIR A;  4Q8G A;  2F7D A;  1NB5 A;  3P5U A;  1M6D A;  1ZCM A;  4YV8 A;  5EF4 A;  3O0U A; 
#chains in the Genus database with same CATH topology
 7PCK A;  2DCC A;  5JH3 A;  3I3T A;  2Y6E A;  3B21 A;  4G54 A;  2CB5 A;  1HUC B;  2CIO A;  5FPW A;  1ITO A;  3F5V A;  4PP1 A;  1BQI A;  1AYV A;  5EZQ A;  1PE6 A;  2BTW A;  3MOR A;  1MHW A;  2PBH A;  2ARY A;  2FQ9 A;  1PPN A;  4MSX A;  4D8B A;  1VSN A;  5PAD A;  1PVJ A;  3ERV A;  4YYU A;  2NQG A;  2OP3 A;  1NB3 A;  3O65 A;  2YJ8 A;  1IWD A;  4CDD B;  4QRX A;  4ZTB A;  3HWN A;  2C0Y A;  4I07 A;  2Z84 A;  1EF7 A;  3CH3 X;  4N4Z A;  2ACT A;  2VHS A;  2VHF A;  3H8C A;  3GCB A;  3P5V A;  4BOP A;  3F75 A;  4AXL A;  2DC6 A;  3H6S A;  3BBA A;  2FRQ A;  3HHA A;  1DF0 A;  5JZE A;  1AYW A;  1CV8 A;  4WA6 A;  2UZJ A;  3C9E A;  2FRA A;  1ME4 A;  1PPO A;  2J7Q C;  2AVW A;  4RNA A;  2BDL A;  1YZB A;  1BGO A;  3C0R A;  2AIM A;  4P6E A;  4D8E A;  2GFO A;  4GUA A;  2PAD A;  3MHS A;  3BPF A;  1GMY A;  2DCA A;  2AYO A;  2XU5 A;  2R9C A;  1CVZ A;  4PAD A;  3IHP A;  2P0R A;  1DEU A;  2FUD A;  2DJG B;  2AYN A;  5CVO B;  1AIM A;  2JRI A;  4BOU A;  1BY8 A;  2AUX A;  4RF1 A;  3B79 A;  2Y5B A;  4CDC B;  3LXS A;  2JQF R;  2R9F A;  1QXP A;  3KW9 A;  3IOQ A;  1VJV A;  3PRM A;  6PAD A;  3N3G A;  1MEM A;  4BS5 A;  1X9Y A;  1ICF A;  2YJB A;  4XR7 A;  5J94 A;  4N79 A;  3TMP A;  4YVA A;  3P5W A;  1ZIV A;  8PCH A;  1KFU L;  1U5I A;  1Y4H A;  2H7J A;  4X6H A;  3E9S A;  2HHN A;  4W5C A;  2IBI A;  1Y08 A;  2E01 A;  3RVX A;  4PP2 E;  4BQV A;  4QRV A;  9PAP A;  3PW3 A;  4X6J A;  1AEC A;  1U9V A;  1TU6 A;  2YJC A;  3N4C A;  3CBJ A;  2FO5 A;  3LFY A;  1YK7 A;  2OZ2 A;  4A5U A;  2DJF B;  1QDQ A;  3USV A;  2NQA A;  4OVZ B;  4FK5 A;  1GCB A;  1F2A A;  2JQG R;  5EGW A;  2JTC A;  4BPV A;  1DKI A;  4AXM A;  4FJC A;  3K9M A;  3IEJ A;  2P86 A;  3PNR A;  4WUR A;  1CB5 A;  3DF0 A;  3K24 A;  5E6J A;  1GEC E;  2BTW B;  4FIP A;  3TRK A;  3WXE A;  3H7D A;  4BSQ A;  2G8J A;  3CH2 X;  3TNX A;  3RVV A;  3BCN A;  1Q6K A;  4BOS A;  1GLO A;  2G7Y A;  2AUZ A;  3S3Q A;  4MM3 B;  2WBF X;  3BB7 A;  4MI7 A;  1EWL A;  2F1G A;  1TLO A;  4BS6 A;  3PHW A;  2P7U A;  2AS8 A;  2XU1 A;  1KXR A;  5CHV A;  2YJ2 A;  1KHQ A;  2DZY A;  2FE8 A;  2R6N A;  1YT7 A;  1POP A;  1CTE A;  2J7Q A;  4YYR A;  5CHT A;  3QT4 A;  2R9N A;  3E1Z B;  3PBH A;  4RY2 A;  4PI3 A;  3OF8 A;  5JA7 A;  2DOS A;  3OIS A;  3KWZ A;  1F29 A;  4PT5 A;  2FT2 A;  3ZUA A;  4DMX A;  2NQI A;  4IP3 A;  3W30 A;  1KFX L;  5A24 A;  1YAL A;  1MS6 A;  4P6G A;  1JQP A;  3QSD A;  4RKX A;  2G8E A;  4DMY A;  3I06 A;  2IPP B;  3PDF A;  1PAD A;  4YYW A;  2YJ9 A;  5CVM A;  5K16 A;  5KO3 A;  4YYV A;  3RNV A;  1PIP A;  3KX1 A;  2G6D A;  4CDF B;  1QOL A;  4HWY A;  3V6E A;  1S4V A;  4KLB A;  1PBH A;  3MHH A;  4YYS A;  2FTD A;  2DCD A;  1PCI A;  1CPJ A;  1THE A;  4D8I A;  3CBK A;  1STF E;  4OVZ A;  4MZO A;  1AU2 A;  3MP2 A;  3OQC A;  1ATK A;  1AYU A;  4YYQ A;  3RVW A;  3HHI A;  1O0E A;  4Q8H A;  5EZS A;  2HH5 A;  2DC7 A;  3PHU A;  2B1M A;  4ZUX U;  2O6X A;  5CVN B;  4M0W A;  4CDE B;  4XUI A;  2DC9 A;  3IFU A;  1CSB B;  1U9Q X;  4BOQ A;  4OEM A;  1F2B A;  4OW0 A;  1U9X A;  1EWM A;  1NPZ A;  2R9M A;  1CJL A;  3W31 A;  2XU3 A;  3H89 A;  3NHE A;  3O1G A;  3KSE A;  3K8U A;  3BWK A;  1FH0 A;  1CQD A;  1CS8 A;  3AI8 A;  1XKG A;  3P5X A;  3BOW A;  2NQD B;  2OUL A;  1KHP A;  3MTV A;  3V6C A;  4XZX A;  3ZNH A;  1MDW A;  4QRG A;  4W4U A;  1ME3 A;  1EWP A;  1MEG A;  2HD5 A;  2DC8 A;  4REZ A;  3IUT A;  2HWK A;  3BPM A;  3OVX A;  2BDZ A;  1EWO A;  3OVZ A;  1NL6 A;  1PPP A;  4P16 A;  4HXD B;  4W5B A;  3U8E A;  4QH6 A;  1SP4 B;  3IV2 A;  2HXZ A;  3BC3 A;  3KFQ A;  4MZS A;  4QBB A;  4X6I A;  1YVB A;  3BY4 A;  1PXV A;  3PRP A;  4CZW A;  2GHU A;  3PT2 A;  3KKU A;  1PPD A;  3M99 A;  2E02 A;  1TL9 A;  1A6R A;  4IUM A;  3S3R A;  4R3D A;  2DZZ A;  4K7C A;  4I05 A;  3N3K A;  3PHX A;  2XU4 A;  4N8W A;  2E00 A;  1AU4 A;  4BOZ A;  3IMA A;  1U9W A;  1AU0 A;  3QJ3 A;  4OEL A;  1YK8 A;  2PNS A;  2PRE A;  3MTN A;  3WXF A;  3WXG A;  2ATO A;  1SNK A;  3OF9 A;  3D6S A;  2E03 A;  2AU1 A;  2BU3 A;  1K3B B;  3HD3 A;  3PSE A;  2FYE A;  1F2C A;  1QMY A;  4I04 A;  1AU3 A;  2DCB A;  2B1N A;  1BP4 A;  1NLJ A;  5F02 A;  3KWB X;  2R9O A;  1UKF A;  1NQC A;  3H8B A;  1MIR A;  4Q8G A;  2AGA A;  4RF0 A;  2F7D A;  1NB5 A;  3P5U A;  1M6D A;  1ZCM A;  4YV8 A;  5EF4 A;  3MJ5 A;  3O0U A; 
#chains in the Genus database with same CATH homology
 7PCK A;  2DCC A;  5JH3 A;  3I3T A;  2Y6E A;  4C5P A;  4G54 A;  2CB5 A;  1HUC B;  2CIO A;  5FPW A;  1ITO A;  3F5V A;  4PP1 A;  1BQI A;  1AYV A;  1PE6 A;  3MOR A;  1MHW A;  2PBH A;  2ARY A;  2FQ9 A;  1PPN A;  4MSX A;  4GUZ A;  1VSN A;  5PAD A;  3ERV A;  4YYU A;  2NQG A;  2OP3 A;  1NB3 A;  2YJ8 A;  1IWD A;  4CDD B;  4QRX A;  3HWN A;  2C0Y A;  4I07 A;  1EF7 A;  3CH3 X;  4N4Z A;  2ACT A;  2VHS A;  2VHF A;  3H8C A;  3GCB A;  3P5V A;  3F75 A;  4AXL A;  2DC6 A;  3H6S A;  2FRQ A;  3HHA A;  1DF0 A;  1AYW A;  1CV8 A;  4WA6 A;  3C9E A;  2FRA A;  1ME4 A;  1PPO A;  2AVW A;  2BDL A;  1BGO A;  2AIM A;  4P6E A;  2GFO A;  2PAD A;  3MHS A;  3BPF A;  1GMY A;  1W4T A;  2DCA A;  2AYO A;  2XU5 A;  2R9C A;  1CVZ A;  4PAD A;  3D9W A;  3IHP A;  2P0R A;  1DEU A;  2FUD A;  2DJG B;  2AYN A;  5CVO B;  1AIM A;  1BY8 A;  2AUX A;  3B79 A;  2Y5B A;  4CDC B;  3LXS A;  2JQF R;  2R9F A;  1QXP A;  3KW9 A;  3LTW A;  3IOQ A;  1VJV A;  6PAD A;  3N3G A;  1MEM A;  4BS5 A;  1X9Y A;  1ICF A;  2YJB A;  4XR7 A;  5J94 A;  4N79 A;  4YVA A;  3P5W A;  1ZIV A;  8PCH A;  1KFU L;  1U5I A;  1Y4H A;  2H7J A;  4X6H A;  2HHN A;  4W5C A;  2IBI A;  1Y08 A;  2E01 A;  3RVX A;  1W5R A;  4PP2 E;  4BQV A;  4QRV A;  9PAP A;  3PW3 A;  4X6J A;  1AEC A;  1U9V A;  1TU6 A;  2YJC A;  3N4C A;  3CBJ A;  2FO5 A;  3LFY A;  1YK7 A;  2OZ2 A;  2DJF B;  1QDQ A;  3USV A;  2NQA A;  4FK5 A;  1GCB A;  1F2A A;  2JQG R;  5EGW A;  4BPV A;  4AXM A;  4FJC A;  3K9M A;  3IEJ A;  2P86 A;  3PNR A;  1CB5 A;  3DF0 A;  3K24 A;  1GEC E;  4FIP A;  3WXE A;  3H7D A;  4BSQ A;  2G8J A;  3CH2 X;  3TNX A;  3RVV A;  3BCN A;  1Q6K A;  1GLO A;  2G7Y A;  2AUZ A;  3S3Q A;  2WBF X;  1EWL A;  2F1G A;  1TLO A;  4BS6 A;  2P7U A;  2AS8 A;  2XU1 A;  1KXR A;  5CHV A;  2YJ2 A;  1KHQ A;  2DZY A;  2R6N A;  1YT7 A;  1POP A;  1CTE A;  4YYR A;  5CHT A;  3QT4 A;  2R9N A;  3E1Z B;  3PBH A;  4RY2 A;  4PI3 A;  3OF8 A;  5JA7 A;  3OIS A;  4NV7 A;  3KWZ A;  1F29 A;  2FT2 A;  3ZUA A;  4DMX A;  2NQI A;  1KFX L;  5A24 A;  1YAL A;  1MS6 A;  4P6G A;  1JQP A;  3QSD A;  2G8E A;  4DMY A;  3I06 A;  2IPP B;  3PDF A;  1PAD A;  4YYW A;  2YJ9 A;  5CVM A;  5K16 A;  4YYV A;  4BGF A;  1PIP A;  3KX1 A;  2G6D A;  4CDF B;  1QOL A;  4HWY A;  3V6E A;  1S4V A;  4KLB A;  1PBH A;  3MHH A;  4YYS A;  2FTD A;  2DCD A;  1PCI A;  1CPJ A;  1THE A;  3CBK A;  1STF E;  4MZO A;  1AU2 A;  1ATK A;  1AYU A;  4YYQ A;  3RVW A;  3HHI A;  1W6F A;  1O0E A;  4Q8H A;  2HH5 A;  2DC7 A;  2B1M A;  4ZUX U;  2O6X A;  1GX3 A;  5CVN B;  4CDE B;  4XUI A;  2DC9 A;  1CSB B;  1U9Q X;  4OEM A;  1F2B A;  1U9X A;  1EWM A;  1NPZ A;  2R9M A;  1CJL A;  2XU3 A;  3H89 A;  3NHE A;  3O1G A;  3KSE A;  3K8U A;  3BWK A;  1FH0 A;  1CQD A;  1CS8 A;  3AI8 A;  1XKG A;  3P5X A;  3BOW A;  2NQD B;  2OUL A;  1KHP A;  3V6C A;  1MDW A;  4QRG A;  4W4U A;  1ME3 A;  1EWP A;  1MEG A;  2HD5 A;  2DC8 A;  3IUT A;  3BPM A;  3OVX A;  2BDZ A;  1E2T A;  1EWO A;  3OVZ A;  1NL6 A;  1PPP A;  2VFC A;  4W5B A;  3U8E A;  4QH6 A;  4B55 A;  1SP4 B;  3IV2 A;  2HXZ A;  3BC3 A;  3KFQ A;  4MZS A;  4QBB A;  4X6I A;  1YVB A;  1PXV A;  4CZW A;  2GHU A;  3KKU A;  1PPD A;  3M99 A;  2E02 A;  1TL9 A;  1A6R A;  3S3R A;  2DZZ A;  4K7C A;  4I05 A;  3N3K A;  2XU4 A;  4N8W A;  2E00 A;  1AU4 A;  3IMA A;  1U9W A;  1AU0 A;  3QJ3 A;  4OEL A;  1YK8 A;  2PNS A;  2PRE A;  3MTN A;  3WXF A;  3WXG A;  2ATO A;  1SNK A;  3OF9 A;  3D6S A;  2E03 A;  2AU1 A;  3HD3 A;  1K3B B;  2VFB A;  2FYE A;  1F2C A;  1QMY A;  4I04 A;  1AU3 A;  2DCB A;  2BSZ A;  2B1N A;  1BP4 A;  1NLJ A;  4NV8 A;  5F02 A;  3KWB X;  2R9O A;  1NQC A;  3H8B A;  1MIR A;  4Q8G A;  2F7D A;  1NB5 A;  3P5U A;  1M6D A;  1ZCM A;  4YV8 A;  5EF4 A;  3O0U A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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